Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGOURX)

Drug Name
USNIC ACID Drug Info
Synonyms
usnic acid; 125-46-2; Usniacin; Usno; Usninsaeure [German]; (+-)-Uanic acid; usnic-acid; Usinic acid; L-Usnic acid; NSC 8517; CCRIS 5518; HSDB 7170; NSC5890; 1,3(2H,9bH)-Dibenzofurandione, 2,6-diacetyl-7,9-dihydroxy-8,9b-dimethyl-; C18H16O7; EINECS 204-740-7; BRN 1299865; 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyl-1,3(2H,9bH)-dibenzofurandione; AI3-50457; CHEBI:2264; NSC8517; NSC5889; 2,6-Diacetyl-7,9-dihydroxy-8,9b-dimethyldibenzo[b,d]furan-1,3(2H,9bh)-dione
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5646
ChEBI ID
CHEBI:2264
CAS Number
CAS 125-46-2
TTD Drug ID
DMGOURX

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting PTPN1 messenger RNA (PTPN1 mRNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [6]
TRYPAN BLUE DM4NTMO Ophthalmic surgery injury PK97 Approved [7]
URSOLIC ACID DM4SOAW Metabolic syndrome x 5C50-5D2Z Phase 2 [8]
ISIS 113715 DMUPD4G Type-2 diabetes 5A11 Phase 2 [9]
ISIS-PTP1Brx DMJGVXT Type-2 diabetes 5A11 Phase 2 [10]
ERTIPROTAFIB DMJXEV7 Type-2 diabetes 5A11 Terminated [11]
Acetate Ion DMD08RH Discovery agent N.A. Investigative [12]
B-Octylglucoside DMMO75G Discovery agent N.A. Investigative [12]
2-Methyl-2,4-Pentanediol DMD45CU Discovery agent N.A. Investigative [12]
Double Oxidized Cysteine DM6TU84 Discovery agent N.A. Investigative [12]
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Drug(s) Affected By C-C motif chemokine 21 (CCL21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [13]
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Dihydroxyacetone DMM1LG2 Sunburn EJ40 Approved [16]
Arsenic DMTL2Y1 N. A. N. A. Approved [17]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [18]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [19]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [20]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [21]
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Drug(s) Affected By Granulocyte-macrophage colony-stimulating factor (CSF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [23]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [24]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [25]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [26]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [27]
Testosterone DM7HUNW Hot flushes GA30 Approved [28]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [29]
Acetylcholine DMDF79Z Cataract 9B10 Approved [30]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [31]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [32]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [33]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [34]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [35]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [36]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [24]
Ethacrynic acid DM60QMR Edema MG29 Approved [37]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [38]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [39]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [40]
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Drug(s) Affected By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fomepizole DM6VOWQ Athylene glycol or methanol poisoning NE61 Approved [41]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [42]
Theophylline DMRJFN9 Bronchitis CA20 Approved [43]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [44]
Ethanol DMDRQZU Chronic pain MG30 Approved [45]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [46]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [47]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [43]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [48]
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Drug(s) Affected By Cyclin-C (CCNC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [49]
Testosterone DM7HUNW Hot flushes GA30 Approved [28]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [50]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [51]
Dihydroxyacetone DMM1LG2 Sunburn EJ40 Approved [16]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [52]
Arsenic DMTL2Y1 N. A. N. A. Approved [53]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [54]
Inecalcitol oral DMU5SZP Acute myeloid leukaemia 2A60 Phase 2 [55]
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Drug(s) Affected By Serine/threonine-protein kinase Chk1 (CHEK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
Methotrexate DM2TEOL Anterior urethra cancer Approved [58]
Quercetin DM3NC4M Obesity 5B81 Approved [59]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [63]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [64]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [65]
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Drug(s) Affected By Glutathione reductase, mitochondrial (GSR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [66]
Ketoprofen DMRKXPT Bursitis Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [67]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [69]
Quercetin DM3NC4M Obesity 5B81 Approved [70]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [71]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [72]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [73]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [74]
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Drug(s) Affected By Glutathione S-transferase A1 (GSTA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [75]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [76]
Thiotepa DMIZKOP Breast cancer 2C60-2C65 Approved [77]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [78]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [79]
Ethacrynic acid DM60QMR Edema MG29 Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [81]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [82]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [83]
Methotrexate DM2TEOL Anterior urethra cancer Approved [84]
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Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [85]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Selenium DM25CGV N. A. N. A. Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [87]
Methotrexate DM2TEOL Anterior urethra cancer Approved [88]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [89]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [90]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [93]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [94]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [95]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [97]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [98]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [99]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [100]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [102]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [103]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [104]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [105]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [106]
Gefitinib DM15F0X Colon adenocarcinoma Approved [107]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [109]
Selenium DM25CGV N. A. N. A. Approved [110]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [111]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [112]
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Drug(s) Affected By Cyclin-dependent kinase 2 (CDK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [113]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [114]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [115]
Selenium DM25CGV N. A. N. A. Approved [49]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [116]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [117]
Methotrexate DM2TEOL Anterior urethra cancer Approved [118]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [89]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
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Drug(s) Affected By G1/S-specific cyclin-D3 (CCND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Gefitinib DM15F0X Colon adenocarcinoma Approved [107]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [119]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [120]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [122]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [123]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [124]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [125]
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Drug(s) Affected By Glutamate--cysteine ligase catalytic subunit (GCLC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [95]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [127]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [69]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [129]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [130]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [131]
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Drug(s) Affected By Cyclin-dependent kinase 6 (CDK6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [86]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [132]
Gefitinib DM15F0X Colon adenocarcinoma Approved [133]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [134]
Methotrexate DM2TEOL Anterior urethra cancer Approved [84]
Quercetin DM3NC4M Obesity 5B81 Approved [59]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [119]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
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Drug(s) Affected By Serine/threonine-protein kinase Chk2 (CHEK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [136]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [63]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [138]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [139]
Testosterone DM7HUNW Hot flushes GA30 Approved [140]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Capsaicin DMGMF6V Back pain ME84.Z Approved [141]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [142]
Methotrexate DM2TEOL Anterior urethra cancer Approved [14]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [143]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [144]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [145]
Paclitaxel DMLB81S Breast carcinoma Approved [146]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [147]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [148]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [149]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [132]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Gefitinib DM15F0X Colon adenocarcinoma Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [153]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [154]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [116]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [154]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [155]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [156]
Methotrexate DM2TEOL Anterior urethra cancer Approved [157]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [158]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [159]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [160]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [161]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Verapamil DMA7PEW Angina pectoris BA40 Approved [162]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [163]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [164]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [105]
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Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [165]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [166]
Selenium DM25CGV N. A. N. A. Approved [110]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [167]
Etretinate DM2CZFA Keratosis ED56 Approved [168]
Methotrexate DM2TEOL Anterior urethra cancer Approved [169]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [170]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [171]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [173]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [174]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Selenium DM25CGV N. A. N. A. Approved [110]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [177]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [178]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [179]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [180]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [182]
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Drug(s) Affected By Ribosomal protein S6 kinase beta-1 (RPS6KB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [183]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [184]
Gefitinib DM15F0X Colon adenocarcinoma Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [187]
Quercetin DM3NC4M Obesity 5B81 Approved [188]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [190]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [193]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [194]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [195]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [164]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [196]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [197]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [198]
Gefitinib DM15F0X Colon adenocarcinoma Approved [199]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [200]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [201]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [202]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [194]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [203]
Paclitaxel DMLB81S Breast carcinoma Approved [204]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [205]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [193]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [164]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [196]
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Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [207]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [208]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [174]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [175]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [209]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [57]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [210]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [211]
Methotrexate DM2TEOL Anterior urethra cancer Approved [212]
Quercetin DM3NC4M Obesity 5B81 Approved [213]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [214]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [215]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [216]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [145]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [217]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [218]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [219]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [220]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [221]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [222]
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Drug(s) Affected By Caspase-4 (CASP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [223]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [83]
Quercetin DM3NC4M Obesity 5B81 Approved [224]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [225]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [226]
Testosterone DM7HUNW Hot flushes GA30 Approved [28]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [227]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [228]
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Drug(s) Affected By Caspase-7 (CASP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [229]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [174]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [230]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [231]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [232]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [232]
Methotrexate DM2TEOL Anterior urethra cancer Approved [88]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [233]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [234]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [172]
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Drug(s) Affected By DNA-dependent protein kinase catalytic subunit (PRKDC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [235]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [236]
Quercetin DM3NC4M Obesity 5B81 Approved [237]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [190]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [73]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [238]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [125]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [227]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [239]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [158]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [222]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [150]
Verapamil DMA7PEW Angina pectoris BA40 Approved [162]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [240]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [241]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Meloxicam DM2AR7L Arthritis FA20 Approved [242]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [116]
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Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [164]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [240]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [243]
Methotrexate DM2TEOL Anterior urethra cancer Approved [118]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [244]
Quercetin DM3NC4M Obesity 5B81 Approved [237]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [245]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [240]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [246]
Ethacrynic acid DM60QMR Edema MG29 Approved [247]
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Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [248]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [249]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [250]
Etretinate DM2CZFA Keratosis ED56 Approved [251]
Quercetin DM3NC4M Obesity 5B81 Approved [237]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [253]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [73]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [254]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [255]
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Drug(s) Affected By Sequestosome-1 (SQSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [256]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [184]
Gefitinib DM15F0X Colon adenocarcinoma Approved [257]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [259]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [177]
Methotrexate DM2TEOL Anterior urethra cancer Approved [88]
Quercetin DM3NC4M Obesity 5B81 Approved [213]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [260]
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Drug(s) Affected By Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [261]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [111]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [262]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [263]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [264]
Testosterone DM7HUNW Hot flushes GA30 Approved [265]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [266]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [267]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [268]
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Drug(s) Affected By Stromal interaction molecule 1 (STIM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [269]
Ethanol DMDRQZU Chronic pain MG30 Approved [270]
Benzatropine DMF7EXL Parkinsonian disorder Approved [271]
Clozapine DMFC71L Schizophrenia 6A20 Approved [271]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [46]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [20]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [272]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [21]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [273]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [274]
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Drug(s) Affected By kinase isozyme 1, mitochondrial (PDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [213]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [62]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [93]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [213]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [275]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [93]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [239]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [269]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [276]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [277]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium release-activated calcium channel protein 1 (ORAI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Testosterone DM7HUNW Hot flushes GA30 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [15]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [239]
Ethanol DMDRQZU Chronic pain MG30 Approved [270]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [278]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [46]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [279]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [280]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [21]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
PTPN1 messenger RNA (PTPN1 mRNA) TTELIN2 PTN1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [2]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [2]
C-C motif chemokine 21 (CCL21) OT7DOXEM CCL21_HUMAN Gene/Protein Processing [3]
Calcium release-activated calcium channel protein 1 (ORAI1) OT2VE9UU CRCM1_HUMAN Gene/Protein Processing [4]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [2]
Caspase-4 (CASP4) OTVQTV1L CASP4_HUMAN Protein Interaction/Cellular Processes [4]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Gene/Protein Processing [5]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [2]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Gene/Protein Processing [4]
Cyclin-C (CCNC) OTMVK4K4 CCNC_HUMAN Gene/Protein Processing [3]

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