Details of the Drug-Related molecule(s) Interaction Atlas

adenosine diphosphate Drug Info

Adenosine diphosphate; 58-64-0; ADP; Adenosine 5'-(trihydrogen diphosphate); adenosine pyrophosphate; adenosine 5'-pyrophosphate; ADP (nucleotide); adenosine-diphosphate; 5'-Adenylphosphoric acid; 5'-Adp; Adenosindiphosphorsaeure; Adenosine 5'-pyrophosphoric acid; Adenosine-5'-diphosphat; Adenosine 5'-diphosphoric acid; Adenosine diphosphoric acid; Ado-5'-P-P; UNII-61D2G4IYVH; H3adp; BRN 0067722; CHEBI:16761; EINECS 200-392-5; 61D2G4IYVH; CHEMBL14830

Cross-matching ID

PubChem CID

6022

ChEBI ID

CHEBI:16761

CAS Number

CAS 58-64-0

TTD Drug ID

DMFUHKP

General Information of Drug (ID: DMFUHKP)

Molecule-Related Drug Atlas

Molecule Type:

DTT

DOT

Drug Status:

Investigative Drug(s)

Approved Drug(s)

Clinical Trial Drug(s)

Discontinued Drug(s)

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Drug(s) Targeting P2Y purinoceptor 13 (P2RY13)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2MeSATP	DMUE0W6	Discovery agent	N.A.	Investigative	[4]
PPADS	DMWHN3T	Discovery agent	N.A.	Investigative	[4]
2MeSADP	DMGADQ1	Discovery agent	N.A.	Investigative	[4]
ATPgammaS	DMXHQIN	Discovery agent	N.A.	Investigative	[4]
2MeSAMP	DMBO2DC	Discovery agent	N.A.	Investigative	[4]
MRS2211	DM2G5ZE	Discovery agent	N.A.	Investigative	[12]
[33P]2MeSADP	DM218VZ	Discovery agent	N.A.	Investigative	[4]
MRS2603	DMNGC79	Discovery agent	N.A.	Investigative	[12]
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Drug(s) Targeting P2Y purinoceptor 12 (P2RY12)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Clopidogrel	DMOL54H	Acute coronary syndrome	BA41	Approved	[3]
Prasugrel	DM7MT6E	Acute coronary syndrome	BA41	Approved	[13]
Brilinta	DMBR01X	Acute coronary syndrome	BA41	Approved	[14]
Cangrelor	DM8JRH0	Thrombosis	DB61-GB90	Approved	[15]
INS-50589	DMKZUVC	Cardiovascular disease	BA00-BE2Z	Phase 2	[16]
Elinogrel	DMA4BRV	Myocardial infarction	BA41-BA43	Phase 1	[17]
ARL-67085	DMY5IM2	Thrombosis	DB61-GB90	Phase 1	[18]
2MeSADP	DMGADQ1	Discovery agent	N.A.	Investigative	[19]
2MeSAMP	DMBO2DC	Discovery agent	N.A.	Investigative	[19]
R-138727	DML49FI	Discovery agent	N.A.	Investigative	[20]
Clopidogrel	DMOL54H	Acute coronary syndrome	BA41	Approved	[36]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[37]
ANTHRAQUINONE	DM29I0Y	Discovery agent	N.A.	Investigative	[38]
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Drug(s) Targeting P2Y purinoceptor 1 (P2RY1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
2MeSATP	DMUE0W6	Discovery agent	N.A.	Investigative	[2]
PPADS	DMWHN3T	Discovery agent	N.A.	Investigative	[2]
2MeSADP	DMGADQ1	Discovery agent	N.A.	Investigative	[19]
ATPgammaS	DMXHQIN	Discovery agent	N.A.	Investigative	[21]
2',3'-ddATP	DMOB7P6	Discovery agent	N.A.	Investigative	[21]
[35S]ADPbetaS	DMAYPTO	Discovery agent	N.A.	Investigative	[22]
MRS2298	DMZ6EGA	Discovery agent	N.A.	Investigative	[23]
MRS2500	DMNGTOY	Discovery agent	N.A.	Investigative	[24]
2,2'-pyridylisatogen tosylate	DMOQDBA	Discovery agent	N.A.	Investigative	[25]
PMID23368907C16	DMPHKJI	Discovery agent	N.A.	Investigative	[26]
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Drug(s) Targeting P2Y purinoceptor 6 (P2RY6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
GC021109	DMQBEYV	Alzheimer disease	8A20	Phase 1	[27]
INS 316	DMTHMEI	Lung cancer	2C25.0	Discontinued in Phase 3	[5]
2MeSATP	DMUE0W6	Discovery agent	N.A.	Investigative	[5]
RB 2	DMCEFUW	Discovery agent	N.A.	Investigative	[28]
PSB-0952	DMW19LB	Discovery agent	N.A.	Investigative	[28]
5BrUTP	DMEVRH4	Discovery agent	N.A.	Investigative	[5]
MRS2782	DMZSO4R	Discovery agent	N.A.	Investigative	[29]
MRS2578	DMKMPS6	Discovery agent	N.A.	Investigative	[30]
UDP-beta-S	DMMWHAV	Discovery agent	N.A.	Investigative	[31]
Up3U	DMKQWSB	Discovery agent	N.A.	Investigative	[31]
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Drug(s) Targeting Long transient receptor potential channel 4 (TRPM4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
AMP-PNP	DMTOK1D	Discovery agent	N.A.	Investigative	[1]
PIP2	DMOZV7N	Discovery agent	N.A.	Investigative	[32]
decavanadate	DMLT1N3	Discovery agent	N.A.	Investigative	[33]
BTP2	DMNM63G	Discovery agent	N.A.	Investigative	[34]
9-phenanthrol	DMJFBQ1	Discovery agent	N.A.	Investigative	[35]
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Drug(s) Affected By 5'-nucleotidase (NT5E)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[39]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[40]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[41]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[42]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[43]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[45]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[46]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[47]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[48]
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Drug(s) Affected By Platelet-derived growth factor subunit B (PDGFB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[49]
Ramipril	DM2R68E	Acute heart failure	BD10-BD13	Approved	[50]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[51]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[52]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[53]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[54]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[55]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[53]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[56]
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Drug(s) Affected By Fibrinogen alpha chain (FGA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[7]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[58]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[59]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[60]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[61]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[62]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[63]
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Drug(s) Affected By Fibrinogen beta chain (FGB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[7]
LY2835219	DM93VBZ	Breast cancer	2C60-2C65	Approved	[64]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[65]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[60]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[61]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[66]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[67]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[68]
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Drug(s) Affected By Fibrinogen gamma chain (FGG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[69]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[41]
LY2835219	DM93VBZ	Breast cancer	2C60-2C65	Approved	[64]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Ursodeoxycholic acid	DMCUT21	Cholelithiasis	DC11	Approved	[70]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[71]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[60]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[72]
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Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[73]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[74]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[75]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[76]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[77]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[78]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[79]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[80]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[81]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[82]
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Drug(s) Affected By Platelet basic protein (PPBP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[83]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[84]
Nortriptyline	DM4KDYJ	Depression	6A70-6A7Z	Approved	[85]
Paroxetine	DM5PVQE	Anxiety disorder	6B00-6B0Z	Approved	[85]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[86]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[87]
Amlodipine	DMBDAZV	Angina pectoris	BA40	Approved	[88]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[89]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[90]
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Drug(s) Affected By Platelet factor 4 (PF4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[83]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[91]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[51]
Fructose	DM43AN2	Vomiting	MD90	Approved	[92]
Nortriptyline	DM4KDYJ	Depression	6A70-6A7Z	Approved	[85]
Paroxetine	DM5PVQE	Anxiety disorder	6B00-6B0Z	Approved	[85]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[93]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[90]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[94]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[95]
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Drug(s) Affected By Thrombospondin-1 (THBS1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[96]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[97]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[51]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[98]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[99]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[100]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[101]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[100]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[102]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[103]
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Drug(s) Affected By P-selectin (SELP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[84]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[104]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[105]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[106]
Amlodipine	DMBDAZV	Angina pectoris	BA40	Approved	[88]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Asasantin	DMCZIHT	Cerebrovascular ischaemia	8B1Z	Approved	[107]
Cimetidine	DMH61ZB	Acid-reflux disorder	DA22	Approved	[108]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[109]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[90]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[110]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[111]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[112]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[113]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[114]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[115]
Secobarbital	DM14RF5	Epilepsy	8A60-8A68	Approved	[116]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[117]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[118]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[119]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[120]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[111]
Carvedilol	DMHTEAO	Chronic heart failure	BD1Z	Approved	[121]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[122]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[123]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[110]
Urokinase	DM0GOUD	Myocardial infarction	BA41-BA43	Approved	[74]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[39]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[113]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[114]
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Drug(s) Affected By CD40 ligand (CD40LG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[124]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[125]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[106]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[126]
Asasantin	DMCZIHT	Cerebrovascular ischaemia	8B1Z	Approved	[107]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[127]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[128]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[129]
Eptifibatide	DMQXTJS	Acute cardiac ischemic events	BA40.Z	Approved	[130]
Candesartan	DMRK8OT	Chronic heart failure	BD1Z	Approved	[127]
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Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[131]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[132]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[133]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[134]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[135]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[136]
Epirubicin	DMPDW6T	Solid tumour/cancer	2A00-2F9Z	Approved	[137]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[138]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[139]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[139]
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Drug(s) Affected By Ephrin type-A receptor 4 (EPHA4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[140]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[9]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[141]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[142]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[140]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[103]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[143]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[57]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Mestranol	DMG3F94	Contraception	QA21	Approved	[140]
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Drug(s) Affected By Tyrosine-protein kinase receptor UFO (AXL)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[144]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[145]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[98]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[145]
Plicamycin	DM7C8YV	Hypercalcaemia	5B91.0	Approved	[146]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[147]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[148]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[148]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[148]
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Drug(s) Affected By Prothrombin (F2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[80]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[51]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[149]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[150]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[151]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[152]
Phytonadione	DM8HDOL	Bleeding disorder	GA20-GA21	Approved	[153]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[57]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[154]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[155]
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Drug(s) Affected By Growth arrest-specific protein 6 (GAS6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[156]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[44]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[157]
Warfarin	DMJYCVW	Atrial fibrillation	BC81.3	Approved	[158]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[159]
Phosphate	DMUXQG7	Constipation	DD91.1	Approved	[156]
Sodium phenylbutyrate	DMXLBCQ	Spinal muscular atrophy	8B61	Approved	[160]
Phenobarbital	DMXZOCG	Cluster headache	8A81.0	Approved	[161]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[162]
Dihydrotestosterone	DM3S8XC	Prostate hyperplasia	GA90	Phase 4	[156]
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Drug(s) Affected By Tyrosine-protein kinase Mer (MERTK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[104]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[163]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[164]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[164]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[165]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[47]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[166]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[61]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[67]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[167]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Long transient receptor potential channel 4 (TRPM4)	TTJ2HKA	TRPM4_HUMAN	Inhibitor (gating inhibitor)	[1]
P2Y purinoceptor 1 (P2RY1)	TTA93TL	P2RY1_HUMAN	Agonist	[2]
P2Y purinoceptor 12 (P2RY12)	TTZ1DT0	P2Y12_HUMAN	Agonist	[3]
P2Y purinoceptor 13 (P2RY13)	TT1FE3L	P2Y13_HUMAN	Agonist	[4]
P2Y purinoceptor 6 (P2RY6)	TTNVSKA	P2RY6_HUMAN	Agonist	[5]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
5'-nucleotidase (NT5E)	OT7J5LT6	5NTD_HUMAN	Gene/Protein Processing	[6]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Protein Interaction/Cellular Processes	[7]
CD40 ligand (CD40LG)	OT75Z6A6	CD40L_HUMAN	Gene/Protein Processing	[8]
Ephrin type-A receptor 4 (EPHA4)	OT3AMK0C	EPHA4_HUMAN	Post-Translational Modifications	[9]
Fibrinogen alpha chain (FGA)	OTMIHY80	FIBA_HUMAN	Protein Interaction/Cellular Processes	[7]
Fibrinogen beta chain (FGB)	OT6RKLI9	FIBB_HUMAN	Protein Interaction/Cellular Processes	[7]
Fibrinogen gamma chain (FGG)	OT5BJSEX	FIBG_HUMAN	Protein Interaction/Cellular Processes	[7]
Growth arrest-specific protein 6 (GAS6)	OTPOPUUE	GAS6_HUMAN	Drug Response	[10]
Mitogen-activated protein kinase 1 (MAPK1)	OTH85PI5	MK01_HUMAN	Post-Translational Modifications	[11]
Mitogen-activated protein kinase 3 (MAPK3)	OTCYKGKO	MK03_HUMAN	Post-Translational Modifications	[11]

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