General Information of Drug (ID: DMG8KS9)

Drug Name
Phenanthrene-9,10-dione Drug Info
Synonyms
Phenanthrene-9,10-dione; 9,10-Phenanthrenequinone; 84-11-7; Phenanthrenequinone; 9,10-PHENANTHRENEDIONE; 9,10-Phenanthraquinone; Phenanthraquinone; 9,10-Phenanthroquinone; 9-10 Phenanthrene quinone; UNII-42L7BZ8H74; CCRIS 7615; Phenanthrene, 9,10-dihydro-9,10-dioxo-; HSDB 4489; EINECS 201-515-5; NSC 10446; phenanthrene-9,10-quinone; BRN 0608838; SMR000150826; CHEMBL51931; MLS000881132; MLS000571180; AI3-23739; CHEBI:37454; YYVYAPXYZVYDHN-UHFFFAOYSA-N; 42L7BZ8H74; MFCD00001163; 9,10-dihydrophenanthrene-9,10-dione; AK-96664
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
6763
ChEBI ID
CHEBI:37454
CAS Number
CAS 84-11-7
TTD Drug ID
DMG8KS9
INTEDE Drug ID
DR0026

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [8]
PACTIMIBE DM0NZDT Arteriosclerosis BD40 Phase 2/3 [9]
K-604 DMQVN6P Arteriosclerosis BD40 Phase 2 [10]
Eldacimibe DML7WP0 Hyperlipidaemia 5C80 Phase 2 [11]
GR148672X DM7W6YN Acute lymphoblastic leukaemia 2A85 Clinical trial [12]
Avasimibe DMFG4OM Peripheral vascular disease BD4Z Discontinued in Phase 3 [13]
E-5324 DM562BM Hyperlipidaemia 5C80 Discontinued in Phase 2 [14]
RP-64477 DMTQ3BS Hyperlipidaemia 5C80 Discontinued in Phase 2 [15]
CI-976 DMBO28J Hyperlipidaemia 5C80 Discontinued in Phase 2 [16]
CL-283796 DM7LIDT Hyperlipidaemia 5C80 Discontinued in Phase 2 [17]
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Drug(s) Targeting Cholinesterase (BCHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hexafluronium bromide DMFY307 Spasm MB47.3 Approved [18]
MEPTAZINOL DMPSB8F Pain MG30-MG3Z Approved [19]
Eptastigmine DMTV7ZM Cognitive impairment 6D71 Phase 3 [20]
(-)-Phenserine DMNCY1I Alzheimer disease 8A20 Phase 3 [21]
Plasma derived human butyrylcholinesterase DMF3IBC Neurotoxicity NE61 Phase 1 [22]
Protexia DME1Y9W Alzheimer disease 8A20 Phase 1 [23]
JES-9501 DMYR3IE Alzheimer disease 8A20 Phase 1 [24]
Tetra-hydro-isoquinoline derivative 3 DMCZA45 N. A. N. A. Patented [25]
Tetra-hydro-isoquinoline derivative 1 DML86IO N. A. N. A. Patented [25]
Tetra-hydro-isoquinoline derivative 2 DM5CKVF N. A. N. A. Patented [25]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [26]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [27]
FENOFIBRIC ACID DMGO2MC Cardiovascular disease BA00-BE2Z Approved [28]
PGF2alpha DM4XAU7 Solid tumour/cancer 2A00-2F9Z Clinical trial [29]
VUFB-11502 DM7WFR0 N. A. N. A. Preclinical [30]
BRN-3548355 DM4KXT0 N. A. N. A. Investigative [31]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [32]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [33]
Trastuzumab emtansine DMU1LXS HER2-positive breast cancer 2C60-2C65 Phase 2 [34]
1H-Indole-2,3-dione DMOZ91H Discovery agent N.A. Investigative [35]
Nitrobenzaldehyde DM4UHB5 N. A. N. A. Investigative [32]
ACMC-209cv7 DMQCSFB N. A. N. A. Investigative [32]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [37]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [39]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [40]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [41]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [42]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [43]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [45]
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Drug(s) Affected By Superoxide dismutase (SOD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [46]
Haloperidol DM96SE0 Delirium Approved [47]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [48]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [51]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [52]
Methotrexate DM2TEOL Anterior urethra cancer Approved [53]
Epinephrine DM3KJBC Acute asthma CA23 Approved [54]
Quercetin DM3NC4M Obesity 5B81 Approved [55]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [56]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [57]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [58]
Verapamil DMA7PEW Angina pectoris BA40 Approved [59]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [60]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [62]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [63]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [64]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Selenium DM25CGV N. A. N. A. Approved [67]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [68]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [71]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [72]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [73]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [74]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [75]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [76]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [79]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [80]
Paclitaxel DMLB81S Breast carcinoma Approved [81]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [82]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [83]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [84]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [85]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [86]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [87]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [88]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [89]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [90]
Verapamil DMA7PEW Angina pectoris BA40 Approved [91]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [92]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [94]
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Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [95]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [96]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [97]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [98]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [99]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [100]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [101]
Quercetin DM3NC4M Obesity 5B81 Approved [102]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [103]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [104]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [105]
Diazepam DM08E9O Alcohol withdrawal Approved [106]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [107]
Desogestrel DM27U4Y Contraception QA21 Approved [107]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [105]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [105]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [108]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [111]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [112]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [90]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [92]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [113]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [114]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [115]
Meloxicam DM2AR7L Arthritis FA20 Approved [116]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [117]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [118]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [86]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [119]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [90]
Verapamil DMA7PEW Angina pectoris BA40 Approved [91]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [48]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [113]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [120]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Meloxicam DM2AR7L Arthritis FA20 Approved [122]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [123]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [115]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [126]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [127]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [128]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [129]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [130]
Verapamil DMA7PEW Angina pectoris BA40 Approved [59]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Selenium DM25CGV N. A. N. A. Approved [132]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [133]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [100]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [101]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [134]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [115]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [136]
Methotrexate DM2TEOL Anterior urethra cancer Approved [124]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [137]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [138]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [127]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [139]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [140]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [141]
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Drug(s) Affected By Claudin-5 (CLDN5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [142]
Guanfacine extended release DMB1CZ8 Attention deficit hyperactivity disorder 6A05.Z Approved [143]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [144]
Glycine DMIOZ29 Allergic rhinitis CA08.0 Approved [145]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [146]
Urethane DM7NSI0 N. A. N. A. Phase 4 [147]
CS-600G DM1PV4Y N. A. N. A. Phase 3 [148]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [149]
LY294002 DMY1AFS Neuroblastoma 2D11.2 Phase 1 [150]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [145]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [151]
Gefitinib DM15F0X Colon adenocarcinoma Approved [152]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [153]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [154]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [155]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [156]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [131]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [157]
Selenium DM25CGV N. A. N. A. Approved [67]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [158]
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Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [159]
Haloperidol DM96SE0 Delirium Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [160]
Selenium DM25CGV N. A. N. A. Approved [161]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [162]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [163]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [165]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [166]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [167]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [58]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [168]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [60]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [169]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [170]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [169]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [171]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [172]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [173]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [175]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [176]
Gefitinib DM15F0X Colon adenocarcinoma Approved [177]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [178]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [179]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [180]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [172]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [181]
Paclitaxel DMLB81S Breast carcinoma Approved [182]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [183]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [171]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [47]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [93]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [174]
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Drug(s) Affected By Nitric oxide synthase 3 (NOS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [185]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [186]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [47]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [188]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [189]
Quercetin DM3NC4M Obesity 5B81 Approved [190]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [191]
Fructose DM43AN2 Vomiting MD90 Approved [192]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [193]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [104]
Indomethacin DMSC4A7 Bursitis Approved [53]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [114]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [196]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [197]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [127]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [198]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [200]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [201]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [80]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [202]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [203]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [204]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [205]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [206]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [207]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [208]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [210]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [211]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [212]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [213]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [214]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [215]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [216]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [105]
Diazepam DM08E9O Alcohol withdrawal Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [218]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [105]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [219]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [105]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [220]
Testosterone DM7HUNW Hot flushes GA30 Approved [221]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [222]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [105]
Diazepam DM08E9O Alcohol withdrawal Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [223]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [105]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [105]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [138]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [224]
Ethacrynic acid DM60QMR Edema MG29 Approved [223]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [105]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [226]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [227]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [228]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [45]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [230]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [45]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [231]
Quercetin DM3NC4M Obesity 5B81 Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [208]
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [230]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [234]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [228]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [233]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [210]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [235]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [236]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [237]
Diazepam DM08E9O Alcohol withdrawal Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [208]
Benzbromarone DMC3YUA Gout FA25 Approved [238]
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [238]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [229]
Nitrazepam DMEGIQ6 Epilepsy 8A60-8A68 Approved [106]
Flunitrazepam DMGR5Z3 Insomnia 7A00-7A0Z Approved [106]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [239]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By L-xylulose reductase (DCXR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [208]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [241]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Ethanol DMDRQZU Chronic pain MG30 Approved [242]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [39]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [233]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [243]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Cholinesterase (BCHE) TTEB0GD CHLE_HUMAN Inhibitor [1]
Liver carboxylesterase (CES1) TTMF541 EST1_HUMAN Inhibitor [1]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
NADPH-dependent carbonyl reductase 1 (CBR1) DE9JFMC CBR1_HUMAN Substrate [2]
Small intestine reductase (AKR1B10) DEP6GT1 AK1BA_HUMAN Substrate [3]
NADPH-dependent carbonyl reductase 3 (CBR3) DEIVKZ8 CBR3_HUMAN Substrate [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [3]
Aflatoxin B1 aldehyde reductase member 2 (AKR7A2) OTGEDDM2 ARK72_HUMAN Biotransformations [4]
Aldo-keto reductase family 1 member B1 (AKR1B1) OTRX72TH ALDR_HUMAN Biotransformations [4]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [3]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Regulation of Drug Effects [5]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Regulation of Drug Effects [5]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Gene/Protein Processing [6]
Aldo-keto reductase family 1 member C4 (AKR1C4) OTW2MMOF AK1C4_HUMAN Biotransformations [7]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [6]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [6]

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114 The effects of quercetin in cultured human RPE cells under oxidative stress and in Ccl2/Cx3cr1 double deficient mice. Exp Eye Res. 2010 Jul;91(1):15-25.
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