General Information of Drug (ID: DMYLOVR)

Drug Name
Aciclovir Drug Info
Synonyms
acyclovir; Acycloguanosine; 59277-89-3; Zovirax; Vipral; Virorax; Wellcome-248U; 9-[(2-Hydroxyethoxy)methyl]guanine; Aciclovirum; Zovir; Aciclovirum [Latin]; Sitavig; Aciclovier; Zyclir; 9-HYROXYETHOXYMETHYLGUANINE; Aciclovirum [INN-Latin]; 2-Amino-9-((2-hydroxyethoxy)methyl)-1H-purin-6(9H)-one; W-248-U; 9-(2-Hydroxyethoxy)methylguanine; Acyclovir-side chain-2-3H; ACYCLOVIR SODIUM; 9-((2-Hydroxyethoxy)methyl)guanine; Acicloftal; Cargosil; BW-248U; UNII-X4HES1O11F; DRG-0008; NSC 645011; CHEBI:2453; CCRIS 1953; Iontophoretic acyclovir
Indication
Disease Entry ICD 11 Status REF
Genital herpes 1A94 Approved [1]
Herpes simplex encephalitis Approved [2]
Herpes simplex infection 1F00 Approved [3]
Herpes simplex labialis 1F00.01 Approved [4]
Varicella 1E90 Approved [5]
Virus infection 1A24-1D9Z Approved [6]
Herpes simplex virus infection 1F00 Phase 3 [7]
Therapeutic Class
Antiviral Agents
Cross-matching ID
PubChem CID
135398513
ChEBI ID
CHEBI:2453
CAS Number
CAS 59277-89-3
TTD Drug ID
DMYLOVR
VARIDT Drug ID
DR00325
ACDINA Drug ID
D00013

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [21]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [22]
Valaciclovir DMHKS94 Genital herpes 1A94 Approved [23]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [8]
Valganciclovir DMS2IUH Virus infection 1A24-1D9Z Approved [24]
Penciclovir DMOUMDV Herpes simplex labialis 1F00.01 Approved [25]
Famciclovir DMJHLSD Meniere disease AB31.0 Approved [26]
Valacyclovir Hydrochloride DM5I1CE Herpes simplex virus infection 1F00 Approved [8]
Foscavir DM9KJLZ Cytomegalovirus retinitis 9B72.00 Approved [24]
Netivudine DMTKRY1 Virus infection 1A24-1D9Z Phase 3 [27]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Folic Acid DMEMBJC Colorectal carcinoma Approved [30]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [31]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [32]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [33]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [35]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [37]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [38]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
Folic Acid DMEMBJC Colorectal carcinoma Approved [40]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [43]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [44]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [45]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [46]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [47]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [48]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [49]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [13]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [50]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [51]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [52]
Entecavir DM7VTQO Hepatitis B virus infection 1E51.0 Approved [53]
Theophylline DMRJFN9 Bronchitis CA20 Approved [50]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [54]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Metformin DM89QE1 Colorectal carcinoma Approved [55]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [14]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [14]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [56]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [14]
Topotecan DMP6G8T Central nervous system neoplasm Approved [14]
Cephalexin DMD5JU8 Acute otitis media AB00 Approved [57]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [58]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [59]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [60]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [61]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [62]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [63]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [64]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [65]
Verapamil DMA7PEW Angina pectoris BA40 Approved [66]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [67]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [68]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [69]
Propranolol DM79NTF Angina pectoris BA40 Approved [70]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [71]
Methotrexate DM2TEOL Anterior urethra cancer Approved [72]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [49]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [13]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [13]
Cefazolin DMPDYFR Bacteremia 1A73 Approved [73]
Olmesartan medoxomil DMWBHRY High blood pressure BA00 Approved [74]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [75]
FLUORESCEIN DMQTFAO Ocular disease 1F00.1Z Approved [76]
Tenofovir DM1IS6U Chronic hepatitis B virus infection Approved [77]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [78]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [49]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [13]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [79]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [80]
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [81]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [82]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [83]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [84]
Cilostazol DMZMSCT Intermittent claudication BD40.00 Approved [85]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Metformin DM89QE1 Colorectal carcinoma Approved [14]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [14]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [14]
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [14]
Topotecan DMP6G8T Central nervous system neoplasm Approved [14]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [58]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [59]
Estrone sulfate DMVBIZL Atrophic vaginitis GA30.2 Approved [14]
N-methylpyridinium DMVUKEW N. A. N. A. Preclinical [14]
[14C]TEA DM6SFYH Discovery agent N.A. Investigative [14]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [10]
Levacecarnine hci DMJBOCR Cognitive impairment 6D71 Approved [86]
Glycine DMIOZ29 Allergic rhinitis CA08.0 Approved [87]
L-glutamine DM69G8X Short bowel syndrome KB89.1 Approved [88]
Valaciclovir DMHKS94 Genital herpes 1A94 Approved [89]
Valganciclovir DMS2IUH Virus infection 1A24-1D9Z Approved [90]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [91]
D-Serine DM3YH4I N. A. N. A. Phase 4 [92]
L-threonine DMFHTBX Discovery agent N.A. Investigative [92]
⏷ Show the Full List of 9 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [93]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [93]
Gefitinib DM15F0X Colon adenocarcinoma Approved [94]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [95]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [96]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [97]
Methotrexate DM2TEOL Anterior urethra cancer Approved [98]
Quercetin DM3NC4M Obesity 5B81 Approved [99]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [100]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Tryptophan DMIBH7M Depression 6A70-6A7Z Approved [102]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [103]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [105]
Testosterone enanthate DMB6871 N. A. N. A. Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [107]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [108]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [109]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Clozapine DMFC71L Schizophrenia 6A20 Approved [114]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [115]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [117]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [118]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [119]
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Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [18]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [18]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Gefitinib DM15F0X Colon adenocarcinoma Approved [128]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [18]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [130]
Selenium DM25CGV N. A. N. A. Approved [131]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [132]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [133]
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Drug(s) Affected By Antileukoproteinase (SLPI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [18]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [134]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [18]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [18]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [18]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [18]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [18]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [18]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [135]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [136]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [137]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [138]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [139]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [129]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [140]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [18]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [141]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [142]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [143]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [144]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [145]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [146]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [149]
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Drug(s) Affected By Interleukin-24 (IL24)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [18]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [127]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [18]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [18]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [150]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [152]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [18]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [20]
Quercetin DM3NC4M Obesity 5B81 Approved [153]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [20]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [20]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [154]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [20]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [20]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [20]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [155]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [156]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [18]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [157]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [18]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [158]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [159]
Quercetin DM3NC4M Obesity 5B81 Approved [153]
Fluoxetine DM3PD2C Bipolar depression Approved [160]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [18]
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Drug(s) Affected By Myelin basic protein (MBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [125]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [161]
Testosterone DM7HUNW Hot flushes GA30 Approved [162]
Leflunomide DMR8ONJ Arthritis FA20 Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [164]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [165]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Clozapine DMFC71L Schizophrenia 6A20 Approved [167]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [168]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Herpes simplex virus DNA polymerase UL30 (HSV UL30) TTIU7X1 DPOL_HHV11 Modulator [8]
Varicella-zoster virus DNA polymerase (VZV ORF28) TTHPJTK DPOL_VZVD Modulator [9]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Alanine/serine/cysteine/threonine transporter 2 (SLC1A5) DTW7AE3 AAAT_HUMAN Substrate [10]
Organic anion transporter 2 (SLC22A7) DT0OC1Q S22A7_HUMAN Substrate [11]
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [12]
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [13]
Multidrug and toxin extrusion protein 2 (SLC47A2) DT3TX4H S47A2_HUMAN Substrate [14]
Multidrug and toxin extrusion protein 1 (SLC47A1) DTZGT0P S47A1_HUMAN Substrate [14]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [15]
Organic anion transporter 1 (SLC22A6) DTQ23VB S22A6_HUMAN Substrate [13]
Organic anion transporter 3 (SLC22A8) DTVP67E S22A8_HUMAN Substrate [16]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3-hydroxyanthranilate 3,4-dioxygenase (HAAO) OTK9Y6SG 3HAO_HUMAN Gene/Protein Processing [17]
Antileukoproteinase (SLPI) OTUNFUU8 SLPI_HUMAN Gene/Protein Processing [18]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Regulation of Drug Effects [19]
Cystine/glutamate transporter (SLC7A11) OTKJ6PXW XCT_HUMAN Gene/Protein Processing [18]
Indoleamine 2,3-dioxygenase 1 (IDO1) OT91DBN7 I23O1_HUMAN Gene/Protein Processing [17]
Interleukin-1 alpha (IL1A) OTPSGILV IL1A_HUMAN Gene/Protein Processing [18]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Gene/Protein Processing [18]
Interleukin-24 (IL24) OT4VUWH1 IL24_HUMAN Gene/Protein Processing [18]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Gene/Protein Processing [18]
Major histocompatibility complex class I-related gene protein (MR1) OTZU3XX7 HMR1_HUMAN Gene/Protein Processing [20]

References

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4 Interventions for prevention of herpes simplex labialis (cold sores on the lips). Cochrane Database Syst Rev. 2015 Aug 7;2015(8):CD010095.
5 Neonatal varicella. Arch Dis Child. 2023 Oct 31:archdischild-2022-324820.
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10 Amino Acid Transporter ATB0,+ as a delivery system for drugs and prodrugs. Curr Drug Targets Immune Endocr Metabol Disord. 2005 Dec;5(4):357-64.
11 Organic anion transporter 2 (SLC22A7) is a facilitative transporter of cGMP. Mol Pharmacol. 2008 Apr;73(4):1151-8.
12 Gene expression in the human intestine and correlation with oral valacyclovir pharmacokinetic parameters. J Pharmacol Exp Ther. 2003 Aug;306(2):778-86.
13 Human organic anion transporters and human organic cation transporters mediate renal antiviral transport. J Pharmacol Exp Ther. 2002 Mar;300(3):918-24.
14 Substrate specificity of MATE1 and MATE2-K, human multidrug and toxin extrusions/H(+)-organic cation antiporters. Biochem Pharmacol. 2007 Jul 15;74(2):359-71.
15 Acyclovir is a substrate for the human breast cancer resistance protein (BCRP/ABCG2): implications for renal tubular transport and acyclovir-induced nephrotoxicity. Can J Physiol Pharmacol. 2011 Sep;89(9):675-80.
16 Expression of organic anion transporter 2 in the human kidney and its potential role in the tubular secretion of guanine-containing antiviral drugs. Drug Metab Dispos. 2012 Mar;40(3):617-24.
17 Mechanisms by which acyclovir reduces the oxidative neurotoxicity and biosynthesis of quinolinic acid. Life Sci. 2007 Feb 13;80(10):918-25.
18 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
19 Acyclovir is a substrate for the human breast cancer resistance protein (BCRP/ABCG2): implications for renal tubular transport and acyclovir-induced nephrotoxicity. Can J Physiol Pharmacol. 2011 Sep;89(9):675-80. doi: 10.1139/y11-045. Epub 2011 Aug 22.
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