General Information of Drug (ID: DMIFOXE)

Drug Name
1,4-Dithiothreitol Drug Info
Synonyms
Cleland's reagent; Dithiothreitol; 1,4-Dithiothreitol; Dithiotreitol; 1,4-Dimercaptobutane-2,3-diol; dl-Dithiothreitol; rac-Dithiothreitol; Cleland reagent; 7634-42-6; 1,4-disulfanylbutane-2,3-diol; Clelands reagent; Sputolysin; DL-threo-1,4-Dimercapto-2,3-butanediol; 1,4-dimercapto-2,3-butanediol; 3483-12-3; 2,3-Butanediol, 1,4-dimercapto-; Threitol, 1,4-dithio-; 1,4-bis(sulfanyl)butane-2,3-diol; trans-1,4-Dimercaptobutane-2,3-diol; L-1,4-Dithiothreitol; L-Dithiothreitol; CHEBI:18320; 1,4-Bissulfanylbutane-2,3-diol
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
19001
ChEBI ID
CHEBI:18320
CAS Number
CAS 7634-42-6
TTD Drug ID
DMIFOXE

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Preclinical Drug(s)
Investigative Drug(s)
Drug(s) Targeting Rotamase B (PPIB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
L-Proline DMKSTWR Malnutrition 5B50-5B71 Approved [11]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [13]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [14]
Trifluridine DMG2YBD Herpetic keratitis 1F00.10 Approved [15]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [16]
Raltitrexed DMT9K8G Rectal adenocarcinoma 2B92 Approved [17]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [18]
Flucytosine DM13VTW Cryptococcal meningitis Approved [19]
Nolatrexed DMOF0CA Solid tumour/cancer 2A00-2F9Z Phase 3 [20]
Plevitrexed (R)-isomer DMTL39C Gastric adenocarcinoma 2B72 Phase 2 [21]
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Drug(s) Targeting HMG-CoA reductase (HMGCR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [22]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [23]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [24]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [25]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [26]
Fluvastatin DM4MDJY Arteriosclerosis BD40 Approved [23]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [27]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [23]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [28]
Teriflunomide DMQ2FKJ Hyperlipidaemia 5C80 Approved [27]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [30]
Estrone DM5T6US Acne vulgaris ED80 Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [32]
Mestranol DMG3F94 Contraception QA21 Approved [29]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [29]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [33]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [34]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [35]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [36]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [37]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [38]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [41]
Vitamin C DMXJ7O8 Adenocarcinoma 2D40 Approved [37]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [42]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [43]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [44]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [45]
Testosterone DM7HUNW Hot flushes GA30 Approved [48]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Folic Acid DMEMBJC Colorectal carcinoma Approved [45]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [49]
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Drug(s) Affected By Calumenin (CALU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Selenium DM25CGV N. A. N. A. Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [38]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [53]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Benzatropine DMF7EXL Parkinsonian disorder Approved [54]
Clozapine DMFC71L Schizophrenia 6A20 Approved [54]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [55]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [56]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Arsenic DMTL2Y1 N. A. N. A. Approved [57]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [58]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [59]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [60]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [60]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [60]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [60]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [61]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [63]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [65]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [66]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [67]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [68]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [64]
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Drug(s) Affected By Superoxide dismutase (SOD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [69]
Haloperidol DM96SE0 Delirium Approved [70]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [71]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [74]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
Epinephrine DM3KJBC Acute asthma CA23 Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Selenium DM25CGV N. A. N. A. Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [81]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [82]
Epinephrine DM3KJBC Acute asthma CA23 Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [84]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [85]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [86]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [87]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [88]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [89]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [91]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [92]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [93]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [67]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [94]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [95]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Etretinate DM2CZFA Keratosis ED56 Approved [98]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [99]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [100]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [101]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [102]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [103]
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Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [104]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [106]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [107]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [108]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Fructose DM43AN2 Vomiting MD90 Approved [110]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [111]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [105]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [112]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [113]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [114]
Testosterone DM7HUNW Hot flushes GA30 Approved [48]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [116]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [117]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [49]
Hexachlorophene DMLKSE0 Bacterial infection 1A00-1C4Z Approved [3]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [118]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [122]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [123]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [125]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [126]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [127]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [128]
Selenium DM25CGV N. A. N. A. Approved [51]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [121]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [67]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [68]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [129]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [130]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [131]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [132]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [133]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [135]
Gefitinib DM15F0X Colon adenocarcinoma Approved [136]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Selenium DM25CGV N. A. N. A. Approved [51]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [139]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [140]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Gefitinib DM15F0X Colon adenocarcinoma Approved [141]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [142]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [143]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [144]
Quercetin DM3NC4M Obesity 5B81 Approved [145]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [146]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [147]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [148]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [127]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [99]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [149]
Methotrexate DM2TEOL Anterior urethra cancer Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inhibin beta E chain (INHBE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [151]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [152]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [151]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [151]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Fluoxetine DM3PD2C Bipolar depression Approved [151]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [125]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [153]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [151]
Panobinostat DM58WKG Chronic graft versus host disease Approved [154]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Testosterone DM7HUNW Hot flushes GA30 Approved [48]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [38]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [158]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [159]
Ethanol DMDRQZU Chronic pain MG30 Approved [160]
Oxymetholone DMFXUT8 Aplastic anemia 3A70 Approved [161]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [162]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [134]
Selenium DM25CGV N. A. N. A. Approved [51]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [163]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [164]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [165]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [168]
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Drug(s) Affected By Reticulocalbin-2 (RCN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Testosterone DM7HUNW Hot flushes GA30 Approved [169]
Leflunomide DMR8ONJ Arthritis FA20 Approved [170]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [38]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [171]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [34]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [172]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [173]
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Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [29]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Fluoxetine DM3PD2C Bipolar depression Approved [174]
Panobinostat DM58WKG Chronic graft versus host disease Approved [154]
Estrone DM5T6US Acne vulgaris ED80 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [176]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [38]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [48]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [41]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [180]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [181]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [182]
Urethane DM7NSI0 N. A. N. A. Phase 4 [183]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [154]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [176]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [184]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [34]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [58]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [185]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [186]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [187]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [7]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [188]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [34]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [192]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [191]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [193]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [194]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [194]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [195]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [196]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [192]
Lansoprazole DMXYLQ3 Gastric ulcer DA60 Approved [196]
Bezafibrate DMZDCS0 Hypercholesterolaemia 5C80.0 Approved [193]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [61]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [62]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [64]
Quercetin DM3NC4M Obesity 5B81 Approved [197]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [64]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [67]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [68]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [130]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Fructose DM43AN2 Vomiting MD90 Approved [199]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [200]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [201]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [175]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [202]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [203]
Leflunomide DMR8ONJ Arthritis FA20 Approved [170]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Succimer DME81IY Metal intoxication NE60 Approved [204]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [205]
pCMPS DMGIS5Q Discovery agent N.A. Investigative [204]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [31]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [207]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [208]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [34]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [50]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [209]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Candida Thymidylate synthase (Candi TMP1) TTU6BFZ TYSY_CANAL Inhibitor [1]
HMG-CoA reductase (HMGCR) TTPADOQ HMDH_HUMAN Inhibitor [1]
Rotamase B (PPIB) TT6ZFQ4 PPIB_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Gene/Protein Processing [2]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1) OTNAZVKB 3BHS1_HUMAN Gene/Protein Processing [3]
Arsenite methyltransferase (AS3MT) OTNLWD0N AS3MT_HUMAN Post-Translational Modifications [4]
Arylamine N-acetyltransferase 1 (NAT1) OTCCNQ3H ARY1_HUMAN Gene/Protein Processing [5]
Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 (PAPSS1) OTY3TQYA PAPS1_HUMAN Gene/Protein Processing [6]
Calumenin (CALU) OTSYQN71 CALU_HUMAN Gene/Protein Processing [7]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Gene/Protein Processing [8]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Gene/Protein Processing [9]
Cyclin-G2 (CCNG2) OTII38K2 CCNG2_HUMAN Gene/Protein Processing [8]
Delta-aminolevulinic acid dehydratase (ALAD) OTHM9GSH HEM2_HUMAN Gene/Protein Processing [10]

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124 Identification of novel activators of the metal responsive transcription factor (MTF-1) using a gene expression biomarker in a microarray compendium. Metallomics. 2020 Sep 23;12(9):1400-1415. doi: 10.1039/d0mt00071j.
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