Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5DSFZ)

Drug Name
Rifampicin Drug Info
Synonyms
Rifadin; Rifadine; Rifagen; Rifaldazin; Rifaldazine; Rifaldin; Rifamor; Rifampicin; Rifampicin SV; Rifampicina; Rifampicina [INN-Spanish]; Rifampicine [French]; Rifampicinum; Rifampicinum [INN-Latin]; Rifamycin AMP; Rifaprodin; Rifcin; Rifinah; Rifobac; Rifoldin; Rifoldine; Riforal; Rimactan; Rimactane; Rimactazid; Rimactizid; Rimazid; Sinerdol; Tubocin; Archidyn; Arficin; Arzide; Benemicin; Dione 21-acetate; Doloresum; Eremfat; Fenampicin; L-5103 Lepetit; rifampin; 13292-46-1; Abrifam; Ba 41166/E; R/AMP; Rifa; Rifam
Indication
Disease Entry ICD 11 Status REF
Non-insulin dependent diabetes 5A11 Approved [1]
Pulmonary tuberculosis 1B10.Z Approved [2]
Cross-matching ID
PubChem CID
135398735
ChEBI ID
CHEBI:27470
CAS Number
CAS 13292-46-1
TTD Drug ID
DM5DSFZ
INTEDE Drug ID
DR1420

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [16]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [17]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [18]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [19]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [20]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [21]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [22]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [23]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [17]
Verapamil DMA7PEW Angina pectoris BA40 Approved [6]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [73]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [75]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [76]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [77]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [78]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [79]
Capsaicin DMGMF6V Back pain ME84.Z Approved [80]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [81]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [24]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [25]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [26]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [27]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [28]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [29]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [22]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [30]
Verapamil DMA7PEW Angina pectoris BA40 Approved [31]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [32]
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [98]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [98]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [98]
Capsaicin DMGMF6V Back pain ME84.Z Approved [83]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [99]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [96]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [100]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [101]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [102]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [97]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [33]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [34]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [35]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [20]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [6]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [36]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [37]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [38]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [39]
Propranolol DM79NTF Angina pectoris BA40 Approved [40]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [86]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [87]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [88]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [89]
Oxatomide DM1F42Z Hay fever CA08.00 Approved [90]
Cinacalcet DMCX0K3 Hyperparathyroidism 5A51 Approved [91]
Capsaicin DMGMF6V Back pain ME84.Z Approved [83]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [77]
Quinidine DMLPICK N. A. N. A. Approved [92]
Buprenorphine DMPRI8G Opioid dependence 6C43.2Z Approved [93]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [41]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [42]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [43]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [44]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [45]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [30]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Estrone DM5T6US Acne vulgaris ED80 Approved [47]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [48]
Ethanol DMDRQZU Chronic pain MG30 Approved [49]
Fomepizole DM6VOWQ Athylene glycol or methanol poisoning NE61 Approved [112]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [113]
Theophylline DMRJFN9 Bronchitis CA20 Approved [97]
Ethanol DMDRQZU Chronic pain MG30 Approved [114]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [116]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [97]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [118]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [50]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [52]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [46]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [53]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [46]
Verapamil DMA7PEW Angina pectoris BA40 Approved [54]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [55]
Estrone DM5T6US Acne vulgaris ED80 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [57]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [82]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [77]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [76]
Capsaicin DMGMF6V Back pain ME84.Z Approved [83]
Zafirlukast DMHNQOG Asthma CA23 Approved [84]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [77]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [85]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [76]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [77]
⏷ Show the Full List of 20 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [58]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [59]
Estrone DM5T6US Acne vulgaris ED80 Approved [52]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [60]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [61]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [62]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [63]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [64]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [65]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [95]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [103]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [104]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [105]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [106]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [107]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [108]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [109]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [110]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [111]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [66]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [50]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [67]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [68]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [46]
Verapamil DMA7PEW Angina pectoris BA40 Approved [69]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [57]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [71]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [94]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [76]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [95]
Capsaicin DMGMF6V Back pain ME84.Z Approved [83]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [77]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [96]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [77]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [94]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [97]
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Drug(s) Affected By Liver carboxylesterase 1 (CES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [119]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [121]
Selenium DM25CGV N. A. N. A. Approved [122]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [125]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [126]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [127]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [128]
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Drug(s) Affected By ATP-binding cassette sub-family C member 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lopinavir DMITQS0 Human immunodeficiency virus infection 1C62 Approved [129]
Sulfinpyrazone DMEV954 Gout FA25 Approved [130]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [131]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [134]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [135]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [136]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [137]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alcohol dehydrogenase 1C (ADH1C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [114]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [141]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [143]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [145]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [146]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [147]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [148]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [149]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [150]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Ethacrynic acid DM60QMR Edema MG29 Approved [152]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [153]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [154]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [155]
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Drug(s) Affected By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [156]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [157]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [156]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [157]
Sulfinpyrazone DMEV954 Gout FA25 Approved [158]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [156]
Zafirlukast DMHNQOG Asthma CA23 Approved [156]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [156]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [159]
Dabrafenib DMX6OE3 Melanoma 2C30 Approved [160]
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Drug(s) Affected By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [73]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [74]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [79]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [79]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [161]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [162]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [163]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [164]
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Drug(s) Affected By ATP-binding cassette sub-family G member 1 (ABCG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [165]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [168]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [168]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
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Drug(s) Affected By Glucocorticoid receptor (NR3C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [171]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Selenium DM25CGV N. A. N. A. Approved [122]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [174]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [178]
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Drug(s) Affected By Cytochrome P450 3A7 (CYP3A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [162]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [180]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [181]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [111]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [183]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [184]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
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Drug(s) Affected By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [185]
Methoxsalen DME8FZ9 Cutaneous T-cell lymphoma 2B01 Approved [186]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [187]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [19]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [189]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [190]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [191]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [192]
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Drug(s) Affected By Cytochrome P450 7A1 (CYP7A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [193]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [196]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [197]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [196]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [200]
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Drug(s) Affected By 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [201]
Calcidiol DMN4CV5 Hypophosphatemia Approved [202]
Calcipotriol DM03CP7 Psoriasis EA90 Approved [203]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [207]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
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Drug(s) Affected By Glutathione S-transferase A1 (GSTA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [210]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [211]
Thiotepa DMIZKOP Breast cancer 2C60-2C65 Approved [212]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [213]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Ethacrynic acid DM60QMR Edema MG29 Approved [215]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [216]
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [217]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
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Drug(s) Affected By Cocaine esterase (CES2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [218]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [219]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [220]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Testosterone enanthate DMB6871 N. A. N. A. Approved [221]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [128]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sterol 26-hydroxylase, mitochondrial (CYP27A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [223]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [224]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [225]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [226]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [227]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 5 (ABCC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [228]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [229]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [230]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [231]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [232]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [234]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Epoxide hydrolase 1 (EPHX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [237]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [238]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [241]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [242]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [243]
Verapamil DMA7PEW Angina pectoris BA40 Approved [244]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [245]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [246]
Selenium DM25CGV N. A. N. A. Approved [247]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [248]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [249]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2F1 (CYP2F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [251]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [252]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [181]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [253]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Cytochrome P450 2C18 (CYP2C18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [157]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [157]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [255]
Lansoprazole DMXYLQ3 Gastric ulcer DA60 Approved [256]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [257]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [259]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2A13 (CYP2A13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [253]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [260]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
HELENALIN DMMCI4H N. A. N. A. Terminated [261]
Acenaphthenol DMT3QYZ N. A. N. A. Investigative [262]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [263]
BRN-3548355 DM4KXT0 N. A. N. A. Investigative [263]
Chrysin DM7V2LG Discovery agent N.A. Investigative [264]
9-phenanthrol DMJFBQ1 Discovery agent N.A. Investigative [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutathione S-transferase P (GSTP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Busulfan DMXYJ9C Chronic myelogenous leukaemia 2A20.0 Approved [266]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [268]
Chlorambucil DMRKE63 Chronic lymphocytic leukaemia 2A82.0 Approved [268]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [269]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [270]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [271]
Selenium DM25CGV N. A. N. A. Approved [122]
Etretinate DM2CZFA Keratosis ED56 Approved [272]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [273]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aryl hydrocarbon receptor (AHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [274]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [275]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [276]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [277]
Quercetin DM3NC4M Obesity 5B81 Approved [278]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [279]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [281]
Herbimycin A DM6YWBF Solid tumour/cancer 2A00-2F9Z Approved [282]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 1 group I member 3 (NR1I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [283]
Quercetin DM3NC4M Obesity 5B81 Approved [284]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [285]
Artemether DM48QOT Malaria 1F40-1F45 Approved [286]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [287]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Estrone DM5T6US Acne vulgaris ED80 Approved [288]
Leflunomide DMR8ONJ Arthritis FA20 Approved [289]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [288]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-aminolevulinate synthase, non-specific, mitochondrial (ALAS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [290]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [292]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [293]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [190]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 120B (TMEM120B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [296]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [299]
Milchsaure DM462BT Pruritus EC90 Investigative [300]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Uncharacterized protein C4orf51 (C4ORF51)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Ankyrin repeat domain-containing protein 65 (ANKRD65)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [176]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [302]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Transcription factor EC (TFEC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [303]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [303]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [303]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [303]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [304]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [258]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [305]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Obscurin-like protein 1 (OBSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [122]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [307]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [308]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PC4 and SFRS1-interacting protein (PSIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Selenium DM25CGV N. A. N. A. Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [310]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SUN domain-containing protein 1 (SUN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Quercetin DM3NC4M Obesity 5B81 Approved [312]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin beta-like protein 1 (ITGBL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [317]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [318]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [319]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [318]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [225]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [321]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [322]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [323]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tissue-type plasminogen activator (PLAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [324]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [325]
Etretinate DM2CZFA Keratosis ED56 Approved [326]
Prednisone DM2HG4X Acute asthma CA23 Approved [327]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [328]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [329]
Fructose DM43AN2 Vomiting MD90 Approved [330]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carbonic anhydrase 1 (CA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [331]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [332]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [333]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [334]
Candesartan DMRK8OT Chronic heart failure BD1Z Approved [331]
Indomethacin DMSC4A7 Bursitis Approved [335]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Phenylephrine DMZHUO5 Allergic rhinitis CA08.0 Approved [337]
GUAIACOL DMN4E7T N. A. N. A. Phase 3 [333]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coagulation factor XIII B chain (F13B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ethanol DMDRQZU Chronic pain MG30 Approved [339]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [341]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myocardial zonula adherens protein (MYZAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [122]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [319]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [343]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [344]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [319]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [345]
Drug(s) Affected By Spectrin beta chain, erythrocytic (SPTB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [346]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [122]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin-6 (MYH6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [348]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [349]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [350]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [349]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [351]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [349]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ETS domain-containing protein Elk-1 (ELK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [352]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [271]
Quercetin DM3NC4M Obesity 5B81 Approved [353]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [354]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Testosterone enanthate DMB6871 N. A. N. A. Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [356]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [357]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Galactoside alpha-(1,2)-fucosyltransferase 1 (FUT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [358]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [359]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [173]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
Testosterone undecanoate DMZO10Y Hypogonadism 5A61.0 Approved [360]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear transcription factor Y subunit alpha (NFYA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [361]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [362]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [363]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paired box protein Pax-7 (PAX7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [366]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [367]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [365]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [365]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [367]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenosine receptor A2a (ADORA2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [368]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [369]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [370]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [369]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [369]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leukocyte tyrosine kinase receptor (LTK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Arsenic DMTL2Y1 N. A. N. A. Approved [371]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Pyruvate kinase PKLR (PKLR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [372]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [145]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [304]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Corticotropin-releasing factor receptor 1 (CRHR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [271]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [373]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [373]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [374]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Nitric oxide synthase, inducible (NOS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Indomethacin DMSC4A7 Bursitis Approved [375]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [376]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [377]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [378]
Quercetin DM3NC4M Obesity 5B81 Approved [379]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [380]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [381]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histamine H1 receptor (HRH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desloratadine DM56YN7 Allergic rhinitis CA08.0 Approved [78]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [78]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [97]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Clozapine DMFC71L Schizophrenia 6A20 Approved [382]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [383]
Olanzapine DMPFN6Y Bipolar depression Approved [382]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanine nucleotide-binding protein G(olf) subunit alpha (GNAL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Azelaic Acid DMHVL0J Acne vulgaris ED80 Approved [384]
Isoproterenol DMK7MEY Atrioventricular block Approved [384]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [385]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [386]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate receptor 1 (GRIA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [387]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [388]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [296]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [321]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [389]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [365]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [344]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [390]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcriptional regulator ATRX (ATRX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [391]
Selenium DM25CGV N. A. N. A. Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [290]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Testosterone enanthate DMB6871 N. A. N. A. Approved [221]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [392]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Ethanol DMDRQZU Chronic pain MG30 Approved [393]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [356]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein kinase CLK2 (CLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [394]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [395]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
T83193 DMHO29Y Discovery agent N.A. Patented [396]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [397]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [398]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Type I iodothyronine deiodinase (DIO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [399]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [400]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [401]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [400]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [402]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [403]
Oxytetracycline DMOVH1M Actinomycosis Approved [404]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serpin B9 (SERPINB9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [405]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [179]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [126]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neural retina-specific leucine zipper protein (NRL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [251]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [406]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [406]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [407]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [258]
TTNPB DMSABD0 Discovery agent N.A. Investigative [406]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Aquaporin-4 (AQP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [408]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [134]
Guanfacine extended release DMB1CZ8 Attention deficit hyperactivity disorder 6A05.Z Approved [408]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ammonia DMOEVK6 Coronary artery disease BA80 Approved [409]
Olanzapine DMPFN6Y Bipolar depression Approved [410]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [411]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By High mobility group nucleosome-binding domain-containing protein 5 (HMGN5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [413]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [414]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [296]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [415]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [416]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Roflumilast DMPGHY8 Asthma CA23 Approved [418]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine-protein kinase ATM (ATM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [419]
Paromomycin DM1AGXN Amoebiasis 1A36 Approved [420]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [421]
Etretinate DM2CZFA Keratosis ED56 Approved [422]
Quercetin DM3NC4M Obesity 5B81 Approved [423]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [424]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [425]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [426]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [427]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 28 kDa heat- and acid-stable phosphoprotein (PDAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [428]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [429]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [430]
CHOLINE DM5D9YK Insomnia 7A00-7A0Z Investigative [431]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [315]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By PCNA-associated factor (PCLAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [432]
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [433]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [434]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Toll-like receptor 1 (TLR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [307]
Arsenic DMTL2Y1 N. A. N. A. Approved [435]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mediator of RNA polymerase II transcription subunit 1 (MED1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [312]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [437]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [438]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [172]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By INO80 complex subunit D (INO80D)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [439]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [440]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [309]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arylsulfatase J (ARSJ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Arsenic DMTL2Y1 N. A. N. A. Approved [441]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [171]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C9orf153 (C9ORF153)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Milchsaure DM462BT Pruritus EC90 Investigative [300]
Drug(s) Affected By Ras-related GTP-binding protein B (RRAGB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
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Drug(s) Affected By Olfactory receptor 4A47 (OR4A47)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By NADH-cytochrome b5 reductase-like (CYB5RL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Transmembrane protein 88 (TMEM88)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [442]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [443]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [444]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [365]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thrombospondin type-1 domain-containing protein 4 (THSD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [225]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [442]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [445]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [365]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exopolyphosphatase PRUNE1 (PRUNE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [116]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [122]
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Drug(s) Affected By General transcription factor II-I repeat domain-containing protein 2A (GTF2IRD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [309]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [411]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [397]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [365]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [305]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Dynein regulatory complex protein 11 (IQCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [208]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [309]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [446]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kin of IRRE-like protein 3 (KIRREL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [345]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Kelch-like protein 23 (KLHL23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [356]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 145 (TMEM145)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [345]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Ethanolamine-phosphate phospho-lyase (ETNPPL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [365]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [411]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [448]
OXYQUINOLINE DMZVS9Y Discovery agent N.A. Investigative [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable mitochondrial glutathione transporter SLC25A40 (SLC25A40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [356]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [449]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [450]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM200A (FAM200A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Milchsaure DM462BT Pruritus EC90 Investigative [300]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Tsukushi (TSKU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [208]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [451]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Septin-8 (SEPTIN8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [122]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein DLX-4 (DLX4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [452]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [453]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [366]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [296]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Bortezomib DMNO38U Leukemia Approved [356]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [414]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [296]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [416]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [312]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [299]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DDB1- and CUL4-associated factor 5 (DCAF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [430]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [454]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protein TBATA (TBATA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Nucleosome assembly protein 1-like 5 (NAP1L5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 2 (AGAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [305]
Drug(s) Affected By Interleukin-12 receptor subunit beta-2 (IL12RB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [455]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [456]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [457]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [457]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [458]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By RANBP2-like and GRIP domain-containing protein 5/6 (RGPD6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [392]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [459]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [398]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [460]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tripartite motif-containing protein 51 (TRIM51)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Sorbin and SH3 domain-containing protein 1 (SORBS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [312]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Testosterone enanthate DMB6871 N. A. N. A. Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [461]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [304]
Arsenic DMTL2Y1 N. A. N. A. Approved [441]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By R-spondin-3 (RSPO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [446]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [448]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein GLIS2 (GLIS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [383]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [462]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [416]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paternally-expressed gene 3 protein (PEG3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [126]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [323]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [302]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [463]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase SIK2 (SIK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [312]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [461]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [312]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Forkhead box protein P1 (FOXP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [461]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5' exonuclease Apollo (DCLRE1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [464]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Arecoline DMFJZK3 Parkinson disease 8A00.0 Phase 1 [465]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [411]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sideroflexin-1 (SFXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [413]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [466]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [466]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [467]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Casein kinase I isoform gamma-1 (CSNK1G1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [433]
Testosterone DM7HUNW Hot flushes GA30 Approved [224]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Synembryn-B (RIC8B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [258]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipase A and acyltransferase 2 (PLAAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [168]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [468]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [448]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Centlein (CNTLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [309]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [407]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [308]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin-related protein 10 (ACTR10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [307]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Drug(s) Affected By Interleukin-37 (IL37)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [469]
Milchsaure DM462BT Pruritus EC90 Investigative [300]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Polycystin-2-like protein 1 (PKD2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [470]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [471]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By ABI gene family member 3 (ABI3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [307]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [341]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [473]
Methyl Mercury Ion DM6YEW4 Discovery agent N.A. Investigative [473]
Drug(s) Affected By Homologous-pairing protein 2 homolog (PSMC3IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [303]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [303]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [383]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By STE20/SPS1-related proline-alanine-rich protein kinase (STK39)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [474]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paired immunoglobulin-like type 2 receptor alpha (PILRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [369]
Prednisolone DMQ8FR2 Acute adrenal insufficiency Approved [369]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [369]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [411]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [446]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrator complex subunit 6 (INTS6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [122]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Testosterone enanthate DMB6871 N. A. N. A. Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cip1-interacting zinc finger protein (CIZ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [307]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [475]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Methotrexate DM2TEOL Anterior urethra cancer Approved [466]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [472]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Multiple inositol polyphosphate phosphatase 1 (MINPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Arsenic DMTL2Y1 N. A. N. A. Approved [476]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein RP/EB family member 3 (MAPRE3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Paclitaxel DMLB81S Breast carcinoma Approved [477]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [344]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RNF6 (RNF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Serum paraoxonase/arylesterase 1 (PON1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [478]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [479]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [480]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [481]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [482]
Quercetin DM3NC4M Obesity 5B81 Approved [483]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [281]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [478]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hexokinase-4 (GCK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [350]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [484]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [485]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Arsenic DMTL2Y1 N. A. N. A. Approved [441]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [296]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [486]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrilin-2 (MATN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [319]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [366]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [487]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Long-chain fatty acid transport protein 2 (SLC27A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [489]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pendrin (SLC26A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epanova DMHEAGL Hypertriglyceridemia 5C80.1 Approved [490]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [491]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
CHLORIDE DM1TJXA Solid tumour/cancer 2A00-2F9Z Phase 3 [492]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
IODIDE DM3FZ6P Discovery agent N.A. Investigative [493]
Formic Acid DMNFZC6 Discovery agent N.A. Investigative [494]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By ABC-type organic anion transporter ABCA8 (ABCA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Indomethacin DMSC4A7 Bursitis Approved [495]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Taurocholic Acid DM2LZ8F Type-2 diabetes 5A11 Phase 1/2 [496]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier organic anion transporter family member 2B1 (SLCO2B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [134]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [168]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [225]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ethanol DMDRQZU Chronic pain MG30 Approved [497]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [168]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 6 (ABCC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzbromarone DMC3YUA Gout FA25 Approved [498]
Verapamil DMA7PEW Angina pectoris BA40 Approved [498]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [499]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [500]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [501]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [231]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [134]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [485]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Folic Acid DMEMBJC Colorectal carcinoma Approved [502]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylcholine translocator ABCB4 (ABCB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [503]
Verapamil DMA7PEW Angina pectoris BA40 Approved [504]
Methysergide DM1EF73 Migraine 8A80 Approved [505]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [505]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [285]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Excitatory amino acid transporter 2 (SLC1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [506]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [237]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Thiamphenicol DMDRKH2 Bacterial infection 1A00-1C4Z Approved [507]
Ampicillin DMHWE7P Acute epiglottitis Approved [506]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [506]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 15 member 1 (SLC15A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [508]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [509]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [510]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [510]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [511]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent betaine transporter (SLC6A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [470]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Sodium chloride DMM3950 Skin burns ME65.0 Approved [512]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent glycine transporter 1 (SLC6A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [270]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [513]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [168]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [168]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [168]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [168]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [168]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [168]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [461]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfate transporter (SLC26A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [432]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [290]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [412]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [173]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amino acid transporter heavy chain SLC3A1 (SLC3A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [514]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [515]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [516]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [516]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [309]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [517]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent phosphate transporter 2 (SLC20A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phosphate DMUXQG7 Constipation DD91.1 Approved [518]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Testosterone DM7HUNW Hot flushes GA30 Approved [224]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [173]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent phosphate transport protein 1 (SLC17A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Sodium-coupled monocarboxylate transporter 2 (SLC5A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [306]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [365]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [389]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [444]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Long-chain fatty acid transport protein 3 (SLC27A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [519]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [461]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [311]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 10 (ABCC10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [137]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [345]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [298]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [520]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Solute carrier family 23 member 3 (SLC23A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Drug(s) Affected By Solute carrier family 25 member 34 (SLC25A34)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [521]
Drug(s) Affected By Calcium/manganese antiporter SLC30A10 (SLC30A10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [489]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [402]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [365]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier organic anion transporter family member 4C1 (SLCO4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [315]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [402]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Monocarboxylate transporter 12 (SLC16A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [231]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [386]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [436]
bilirubin DMI0V4O Discovery agent N.A. Investigative [522]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [523]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Equilibrative nucleoside transporter 4 (SLC29A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [524]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [514]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [383]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Epinephrine DM3KJBC Acute asthma CA23 Approved [524]
Norepinephrine DMOUC09 Alopecia ED70 Approved [524]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysosomal proton-coupled steroid conjugate and bile acid symporter SLC46A3 (SLC46A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [309]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [345]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [411]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Organic solute transporter subunit alpha (SLC51A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [135]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Organic solute transporter subunit beta (SLC51B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [243]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [135]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [207]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [135]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [525]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Organic anion transporter 7 (SLC22A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [526]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [526]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [526]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [526]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [526]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family F member 1 (ABCF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [222]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [312]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [312]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [258]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [454]
Hexadecanoic acid DMWUXDZ Discovery agent N.A. Investigative [527]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [528]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 12 (SLC2A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [126]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Folic Acid DMEMBJC Colorectal carcinoma Approved [320]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [383]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [517]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [365]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/myo-inositol cotransporter 2 (SLC5A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [386]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [144]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [469]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [305]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Multidrug and toxin extrusion protein 1 (SLC47A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [529]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [530]
Verapamil DMA7PEW Angina pectoris BA40 Approved [531]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [530]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Quinidine DMLPICK N. A. N. A. Approved [530]
Mebendazole DMO14SG Ascariasis 1F62 Approved [532]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 11 (ABCC11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [533]
Methotrexate DM2TEOL Anterior urethra cancer Approved [534]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [534]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [533]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [535]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-coupled neutral amino acid symporter 2 (SLC38A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [536]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Fluoxetine DM3PD2C Bipolar depression Approved [537]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [425]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [425]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Equilibrative nucleoside transporter 1 (SLC29A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [538]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [539]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [540]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Testosterone DM7HUNW Hot flushes GA30 Approved [208]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [365]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family A member 2 (ABCA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [295]
Bortezomib DMNO38U Leukemia Approved [356]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Methotrexate DM2TEOL Anterior urethra cancer Approved [541]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [541]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family G member 8 (ABCG8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [542]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [543]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [544]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial glutamate carrier 1 (SLC25A22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Selenium DM25CGV N. A. N. A. Approved [122]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [449]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [545]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [545]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family B member 6 (ABCB6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [519]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [168]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Paclitaxel DMLB81S Breast carcinoma Approved [137]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent transporter XTRP3 (SLC6A20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [270]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [236]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [545]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [344]
Chlorothiazide DMLHESP Chronic heart failure BD1Z Approved [546]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [386]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier organic anion transporter family member 1B3 (SLCO1B3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [547]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [548]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [549]
Trospium chloride DM32XZT Discovery agent N.A. Approved [550]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [135]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [135]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [338]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [551]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 23 member 2 (SLC23A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [552]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [356]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [362]
Arsenic DMTL2Y1 N. A. N. A. Approved [364]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/hydrogen exchanger 8 (SLC9A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [314]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [297]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Long-chain fatty acid transport protein 5 (SLC27A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [388]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Olanzapine DMPFN6Y Bipolar depression Approved [553]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Berberine DMC5Q8X N. A. N. A. Phase 4 [554]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [555]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [126]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [556]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [342]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [557]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fatty acid synthase (FASN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [543]
Selenium DM25CGV N. A. N. A. Approved [122]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [558]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [560]
Quercetin DM3NC4M Obesity 5B81 Approved [561]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [285]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [562]
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Drug(s) Affected By Solute carrier family 22 member 1 (SLC22A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [563]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [564]
Trospium chloride DM32XZT Discovery agent N.A. Approved [550]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [565]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [566]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [526]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [526]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
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Drug(s) Affected By Transmembrane protease serine 2 (TMPRSS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [567]
Diazepam DM08E9O Alcohol withdrawal Approved [567]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Selenium DM25CGV N. A. N. A. Approved [122]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [567]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [567]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [567]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [567]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [567]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [567]
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Drug(s) Affected By ATP-binding cassette sub-family C member 3 (ABCC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [568]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [569]
Calcipotriol DM03CP7 Psoriasis EA90 Approved [193]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [270]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [230]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Prednisone DM2HG4X Acute asthma CA23 Approved [570]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [571]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [572]
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Drug(s) Affected By CASP8 and FADD-like apoptosis regulator (CFLAR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [452]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [573]
Methotrexate DM2TEOL Anterior urethra cancer Approved [574]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [575]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [576]
Quercetin DM3NC4M Obesity 5B81 Approved [577]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [578]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Ethacrynic acid DM60QMR Edema MG29 Approved [579]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [580]
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Drug(s) Affected By Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [581]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [582]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [583]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Quercetin DM3NC4M Obesity 5B81 Approved [584]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [585]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [586]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [587]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [588]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [588]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [589]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [590]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [591]
Etidronic acid DM1XHYJ Bone Paget disease Approved [588]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [588]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [588]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [283]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [592]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [593]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [594]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [594]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [145]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [593]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [594]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [505]
Gefitinib DM15F0X Colon adenocarcinoma Approved [593]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [595]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [593]
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Drug(s) Affected By Phospholipid-transporting ATPase ABCA1 (ABCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [223]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [165]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Fluoxetine DM3PD2C Bipolar depression Approved [537]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [596]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [597]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [542]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [598]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [599]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 19 (FGF19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [135]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Panobinostat DM58WKG Chronic graft versus host disease Approved [365]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [135]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [222]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [135]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [383]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [600]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [601]
Fructose DM43AN2 Vomiting MD90 Approved [97]
Ketoprofen DMRKXPT Bursitis Approved [97]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [602]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [603]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [604]
Gefitinib DM15F0X Colon adenocarcinoma Approved [605]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [606]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [607]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon gamma (IFNG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [304]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [608]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [609]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [610]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [611]
Quercetin DM3NC4M Obesity 5B81 Approved [612]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [613]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [614]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [555]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [615]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [616]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [616]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Allopurinol DMLPAOB Gout FA25 Approved [617]
Ticlopidine DMO946V Acute coronary syndrome BA41 Approved [618]
Selenium DM25CGV N. A. N. A. Approved [122]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [616]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [142]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apolipoprotein C-III (APOC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [619]
Allopurinol DMLPAOB Gout FA25 Approved [559]
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Drug(s) Affected By Apolipoprotein B-100 (APOB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [620]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [621]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [622]
Bendroflumethiazide DM7EVLC High blood pressure BA00 Approved [623]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [369]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [624]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [519]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [243]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [625]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [245]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [607]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [626]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [627]
Methotrexate DM2TEOL Anterior urethra cancer Approved [369]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein disulfide-isomerase (P4HB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Etretinate DM2CZFA Keratosis ED56 Approved [272]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Quercetin DM3NC4M Obesity 5B81 Approved [628]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [425]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [629]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [630]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [631]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [632]
Cepharanthine DM9Y5JB N. A. N. A. Approved [633]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [634]
Clozapine DMFC71L Schizophrenia 6A20 Approved [635]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [636]
Trifluoperazine DMKBYWI Anxiety Approved [637]
Olanzapine DMPFN6Y Bipolar depression Approved [635]
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Drug(s) Affected By Stromelysin-1 (MMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [97]
Fluvastatin DM4MDJY Arteriosclerosis BD40 Approved [97]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [97]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [97]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [638]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [324]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [639]
Methotrexate DM2TEOL Anterior urethra cancer Approved [640]
Quercetin DM3NC4M Obesity 5B81 Approved [641]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [329]
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Drug(s) Affected By Granzyme B (GZMB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [642]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [643]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [644]
Menthol DMG2KW7 Back pain ME84.Z Approved [645]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [646]
Bortezomib DMNO38U Leukemia Approved [356]
Ethambutol DMR87LC Pulmonary tuberculosis 1B10.Z Approved [647]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [648]
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [97]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [649]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [650]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [651]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [652]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [653]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [97]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [519]
Verapamil DMA7PEW Angina pectoris BA40 Approved [654]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [655]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [603]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [656]
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Drug(s) Affected By Endoplasmic reticulum chaperone BiP (HSPA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [657]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [658]
Etretinate DM2CZFA Keratosis ED56 Approved [272]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [659]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [660]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [661]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [662]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [663]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By POU domain, class 2, transcription factor 1 (POU2F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Ethanol DMDRQZU Chronic pain MG30 Approved [664]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [665]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [666]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [667]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [665]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [666]
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Drug(s) Affected By HLA class I histocompatibility antigen, alpha chain G (HLA-G)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [122]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [616]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [616]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [290]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [616]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [616]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [616]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [616]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [582]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [668]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [271]
Selenium DM25CGV N. A. N. A. Approved [122]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [536]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [585]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [586]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [669]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [394]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Quercetin DM3NC4M Obesity 5B81 Approved [670]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [585]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [671]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [587]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [672]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [673]
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Drug(s) Affected By Alanine aminotransferase 1 (GPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [97]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [674]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [675]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [97]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [97]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [97]
Gefitinib DM15F0X Colon adenocarcinoma Approved [676]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [677]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [676]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [676]
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Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [678]
Folic Acid DMEMBJC Colorectal carcinoma Approved [679]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [680]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [681]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [366]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [136]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [682]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [683]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [683]
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Drug(s) Affected By Interleukin-13 (IL13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [684]
Prednisone DM2HG4X Acute asthma CA23 Approved [685]
Methotrexate DM2TEOL Anterior urethra cancer Approved [686]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [687]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [688]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Budesonide DMJIBAW Allergic rhinitis CA08.0 Approved [689]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [687]
Ethambutol DMR87LC Pulmonary tuberculosis 1B10.Z Approved [647]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [690]
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Drug(s) Affected By Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [691]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [692]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [207]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucose-6-phosphatase catalytic subunit 1 (G6PC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Fluoxetine DM3PD2C Bipolar depression Approved [693]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [207]
Leflunomide DMR8ONJ Arthritis FA20 Approved [289]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [145]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [694]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [242]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [695]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [582]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [668]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [696]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [659]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [697]
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [258]
Gefitinib DM15F0X Colon adenocarcinoma Approved [698]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [699]
Epinephrine DM3KJBC Acute asthma CA23 Approved [700]
Quercetin DM3NC4M Obesity 5B81 Approved [701]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
Fructose DM43AN2 Vomiting MD90 Approved [330]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [702]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [703]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [704]
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Drug(s) Affected By MAP kinase-activated protein kinase 2 (MAPKAPK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [705]
Methotrexate DM2TEOL Anterior urethra cancer Approved [706]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [707]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [233]
Sorbitol DMAN0DE Constipation DD91.1 Approved [705]
Bortezomib DMNO38U Leukemia Approved [356]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [708]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [336]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [709]
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Drug(s) Affected By Cytochrome P450 2J2 (CYP2J2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [710]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [711]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [255]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [710]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [710]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [313]
Gemfibrozil DMD8Q3J Hyperlipidaemia 5C80 Approved [712]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [712]
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Drug(s) Affected By Microsomal triglyceride transfer protein large subunit (MTTP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [713]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [713]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [714]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [715]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [235]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [650]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [716]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [519]
Verapamil DMA7PEW Angina pectoris BA40 Approved [654]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [452]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [717]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [718]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [271]
Meloxicam DM2AR7L Arthritis FA20 Approved [719]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [720]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [721]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [722]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [723]
Selenium DM25CGV N. A. N. A. Approved [122]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [724]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [725]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [576]
Quercetin DM3NC4M Obesity 5B81 Approved [577]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [151]
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Drug(s) Affected By Sequestosome-1 (SQSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [726]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [727]
Gefitinib DM15F0X Colon adenocarcinoma Approved [728]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [729]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [730]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [536]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [731]
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Drug(s) Affected By Hepatic sodium/bile acid cotransporter (SLC10A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [197]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [732]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [733]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
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Drug(s) Affected By Nuclear receptor subfamily 0 group B member 2 (NR0B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcipotriol DM03CP7 Psoriasis EA90 Approved [193]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [734]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [194]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [734]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [735]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [736]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Fluoxetine DM3PD2C Bipolar depression Approved [734]
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Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [737]
Verapamil DMA7PEW Angina pectoris BA40 Approved [244]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [582]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [738]
Selenium DM25CGV N. A. N. A. Approved [122]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [739]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [740]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [741]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [742]
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Drug(s) Affected By Na(+)/citrate cotransporter (SLC13A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [176]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Testosterone DM7HUNW Hot flushes GA30 Approved [224]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [294]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [743]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [347]
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Drug(s) Affected By Scavenger receptor class B member 1 (SCARB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [744]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [745]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [736]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [599]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [746]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [190]
Ethanol DMDRQZU Chronic pain MG30 Approved [747]
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Drug(s) Affected By V-type proton ATPase 116 kDa subunit a 1 (ATP6V0A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [290]
Leflunomide DMR8ONJ Arthritis FA20 Approved [209]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [239]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [138]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [748]
Urethane DM7NSI0 N. A. N. A. Phase 4 [301]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [290]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [254]
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Drug(s) Affected By Major histocompatibility complex class I-related gene protein (MR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [616]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [616]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [616]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [749]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [616]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [616]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
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Drug(s) Affected By Angiotensin-converting enzyme 2 (ACE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Captopril DM458UM Chronic heart failure BD1Z Approved [750]
Diazepam DM08E9O Alcohol withdrawal Approved [567]
Dantrolene DM1D8XY Hyperthermia MG26 Approved [567]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [567]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [567]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [567]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [567]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [567]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [567]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [567]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [727]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [751]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [752]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [199]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [753]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [754]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [672]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [755]
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Drug(s) Affected By Serine/threonine-protein kinase Sgk2 (SGK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [291]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [343]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
Ampicillin DMHWE7P Acute epiglottitis Approved [176]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [340]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [267]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [204]
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Drug(s) Affected By Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [581]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [582]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [559]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [173]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Quercetin DM3NC4M Obesity 5B81 Approved [756]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [585]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [586]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [587]
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Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [757]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [757]
Gefitinib DM15F0X Colon adenocarcinoma Approved [758]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [97]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [759]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [760]
Methotrexate DM2TEOL Anterior urethra cancer Approved [761]
Quercetin DM3NC4M Obesity 5B81 Approved [762]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [763]
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Drug(s) Affected By Angiopoietin-related protein 3 (ANGPTL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [713]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Allopurinol DMLPAOB Gout FA25 Approved [559]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [713]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [544]
Indomethacin DMSC4A7 Bursitis Approved [559]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
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Drug(s) Affected By Solute carrier family 22 member 7 (SLC22A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [526]
Methotrexate DM2TEOL Anterior urethra cancer Approved [195]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [488]
Paclitaxel DMLB81S Breast carcinoma Approved [764]
Allopurinol DMLPAOB Gout FA25 Approved [764]
Bumetanide DMRV7H0 Congestive heart failure BD10 Approved [764]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [764]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [764]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [764]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [765]
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Drug(s) Affected By Solute carrier organic anion transporter family member 1B1 (SLCO1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Enalapril DMNFUZR Congestive heart failure BD10 Approved [766]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [767]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [145]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [768]
Methotrexate DM2TEOL Anterior urethra cancer Approved [769]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [770]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [771]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [771]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [549]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [772]
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Drug(s) Affected By Arylacetamide deacetylase (AADAC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [316]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [144]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [117]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [140]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [140]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [144]
Rifapentine DMCHV4I Pulmonary tuberculosis 1B10.Z Approved [773]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [774]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [3]
Cytochrome P450 2E1 (CYP2E1) DEVDYN7 CP2E1_HUMAN Substrate [4]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [5]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [6]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [7]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Substrate [8]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [9]
Rifampicin monooxygenase (rox) DE6PKFB ROX_NOCFA Substrate [10]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial (CYP24A1) OTG2T749 CP24A_HUMAN Gene/Protein Processing [11]
28 kDa heat- and acid-stable phosphoprotein (PDAP1) OTJSWMOD HAP28_HUMAN Gene/Protein Processing [12]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D) OT1RWFV0 PDE4D_HUMAN Gene/Protein Processing [12]
5' exonuclease Apollo (DCLRE1B) OT2LFW7A DCR1B_HUMAN Gene/Protein Processing [12]
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS1) OTQY6ZSF HEM1_HUMAN Gene/Protein Processing [13]
ABC-type organic anion transporter ABCA8 (ABCA8) OTCWLX6N ABCA8_HUMAN Gene/Protein Processing [14]
ABI gene family member 3 (ABI3) OTQTDSHP ABI3_HUMAN Gene/Protein Processing [12]
Actin-related protein 10 (ACTR10) OTRF3E58 ARP10_HUMAN Gene/Protein Processing [12]
Adenosine receptor A2a (ADORA2A) OTVRBZ0I AA2AR_HUMAN Gene/Protein Processing [12]
Alanine aminotransferase 1 (GPT) OTOXOA0Q ALAT1_HUMAN Gene/Protein Processing [15]

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586 NGBR is required to ameliorate type 2 diabetes in mice by enhancing insulin sensitivity. J Biol Chem. 2021 Jan-Jun;296:100624. doi: 10.1016/j.jbc.2021.100624. Epub 2021 Apr 2.
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744 Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation. PLoS One. 2012;7(3):e33592. doi: 10.1371/journal.pone.0033592. Epub 2012 Mar 19.
745 Induction of scavenger receptor class B type I is critical for simvastatin enhancement of high-density lipoprotein-induced anti-inflammatory actions in endothelial cells. J Immunol. 2008 Nov 15;181(10):7332-40. doi: 10.4049/jimmunol.181.10.7332.
746 Carotenoid transport is decreased and expression of the lipid transporters SR-BI, NPC1L1, and ABCA1 is downregulated in Caco-2 cells treated with ezetimibe. J Nutr. 2005 Oct;135(10):2305-12. doi: 10.1093/jn/135.10.2305.
747 Prenatal ethanol exposure-induced a low level of foetal blood cholesterol and its mechanism of IGF1-related placental cholesterol transport dysfunction. Toxicology. 2019 Aug 1;424:152237. doi: 10.1016/j.tox.2019.152237. Epub 2019 Jun 18.
748 Reproducible chemical-induced changes in gene expression profiles in human hepatoma HepaRG cells under various experimental conditions. Toxicol In Vitro. 2009 Apr;23(3):466-75. doi: 10.1016/j.tiv.2008.12.018. Epub 2008 Dec 30.
749 Genomic profiling uncovers a molecular pattern for toxicological characterization of mutagens and promutagens in vitro. Toxicol Sci. 2011 Jul;122(1):185-97.
750 Polymorphisms of ACE2 gene are associated with essential hypertension and antihypertensive effects of Captopril in women. Clin Pharmacol Ther. 2007 Aug;82(2):187-96. doi: 10.1038/sj.clpt.6100214. Epub 2007 May 2.
751 Repression of Kisspeptin1 weakens hydrogen peroxide-caused injury in HTR8 cells via adjusting PI3K/AKT/mTOR pathway. J Biochem Mol Toxicol. 2020 May;34(5):e22461. doi: 10.1002/jbt.22461. Epub 2020 Feb 11.
752 Low Autophagy (ATG) Gene Expression Is Associated with an Immature AML Blast Cell Phenotype and Can Be Restored during AML Differentiation Therapy. Oxid Med Cell Longev. 2018 Mar 18;2018:1482795. doi: 10.1155/2018/1482795. eCollection 2018.
753 Arsenic trioxide induces autophagic cell death in osteosarcoma cells via the ROS-TFEB signaling pathway. Biochem Biophys Res Commun. 2018 Jan 29;496(1):167-175. doi: 10.1016/j.bbrc.2018.01.018. Epub 2018 Jan 4.
754 TNF enhances trovafloxacin-induced in vitro hepatotoxicity by inhibiting protective autophagy. Toxicol Lett. 2021 May 15;342:73-84. doi: 10.1016/j.toxlet.2021.02.009. Epub 2021 Feb 17.
755 Dihydroceramide accumulation mediates cytotoxic autophagy of cancer cells via autolysosome destabilization. Autophagy. 2016 Nov;12(11):2213-2229. doi: 10.1080/15548627.2016.1213927. Epub 2016 Sep 16.
756 Effect of quercetin on apoptosis of PANC-1 cells. J Korean Surg Soc. 2013 Dec;85(6):249-60. doi: 10.4174/jkss.2013.85.6.249. Epub 2013 Nov 26.
757 Localization of breast cancer resistance protein (Bcrp) in endocrine organs and inhibition of its transport activity by steroid hormones. Cell Tissue Res. 2012 Aug;349(2):551-63. doi: 10.1007/s00441-012-1417-5. Epub 2012 May 13.
758 Pharmacogenetics of ABCG2 and adverse reactions to gefitinib. J Natl Cancer Inst. 2006 Dec 6;98(23):1739-42.
759 ABCG2 polymorphism is associated with the low-density lipoprotein cholesterol response to rosuvastatin. Clin Pharmacol Ther. 2010 May;87(5):558-62.
760 Ciprofloxacin mediates cancer stem cell phenotypes in lung cancer cells through caveolin-1-dependent mechanism. Chem Biol Interact. 2016 Apr 25;250:1-11.
761 Proteomic identification of differentially expressed proteins associated with the multiple drug resistance in methotrexate-resistant human breast cancer cells. Int J Oncol. 2014 Jul;45(1):448-58.
762 Activation of beta-catenin signalling by GSK-3 inhibition increases p-glycoprotein expression in brain endothelial cells. J Neurochem. 2008 Aug;106(4):1855-65. doi: 10.1111/j.1471-4159.2008.05537.x. Epub 2008 Jul 4.
763 Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps. Cancer Biol Ther. 2005 Jul;4(7):747-52.
764 Transport mechanism and substrate specificity of human organic anion transporter 2 (hOat2 [SLC22A7]). J Pharm Pharmacol. 2005 May;57(5):573-8.
765 A species difference in the transport activities of H2 receptor antagonists by rat and human renal organic anion and cation transporters. J Pharmacol Exp Ther. 2005 Oct;315(1):337-45.
766 Effect of organic anion-transporting polypeptide 1B1 (OATP1B1) polymorphism on the single- and multiple-dose pharmacokinetics of enalapril in healthy Chinese adult men. Clin Ther. 2011 May;33(5):655-63. doi: 10.1016/j.clinthera.2011.04.018.
767 Differential interaction of 3-hydroxy-3-methylglutaryl-coa reductase inhibitors with ABCB1, ABCC2, and OATP1B1. Drug Metab Dispos. 2005 Apr;33(4):537-46.
768 Polymorphic organic anion transporting polypeptide 1B1 is a major determinant of repaglinide pharmacokinetics. Clin Pharmacol Ther. 2005 Jun;77(6):468-78. doi: 10.1016/j.clpt.2005.01.018.
769 SLC19A1, SLC46A1 and SLCO1B1 polymorphisms as predictors of methotrexate-related toxicity in Portuguese rheumatoid arthritis patients. Toxicol Sci. 2014 Nov;142(1):196-209. doi: 10.1093/toxsci/kfu162. Epub 2014 Aug 14.
770 SLCO1B1 variants and statin-induced myopathy--a genomewide study. N Engl J Med. 2008 Aug 21;359(8):789-99.
771 Transport of fluorescent chenodeoxycholic acid via the human organic anion transporters OATP1B1 and OATP1B3. J Lipid Res. 2006 Jun;47(6):1196-202.
772 Severe toxicities after irinotecan-based chemotherapy in a patient with lung cancer: a homozygote for the SLCO1B1*15 allele. Ther Drug Monit. 2007 Oct;29(5):666-8. doi: 10.1097/FTD.0b013e3181357364.
773 Human arylacetamide deacetylase is responsible for deacetylation of rifamycins: rifampicin, rifabutin, and rifapentine. Biochem Pharmacol. 2011 Dec 1;82(11):1747-56.
774 Species differences in tissue distribution and enzyme activities of arylacetamide deacetylase in human, rat, and mouse. Drug Metab Dispos. 2012 Apr;40(4):671-9. doi: 10.1124/dmd.111.043067. Epub 2011 Dec 29.