General Information of Drug (ID: DM8M2N3)

Drug Name
GLYCYRRHIZIN Drug Info
Synonyms
Glycyrrhizic acid; glycyrrhizin; Glycyrrhizinic acid; 1405-86-3; Glycyron; Glycyrrhetinic acid glycoside; glyzyrrhizin; 18-beta-Glycyrrhizic acid; Glycyrrizin; Liquorice; UNII-6FO62043WK; Rizinsan K2 A2 (free acid); HSDB 496; EINECS 215-785-7; C42H62O16; Glycyrrhizin [JAN]; NSC 167409; NSC 234419; BRN 0077922; CHEMBL441687; NSC 2800; beta-Glycyrrhizin; CHEBI:15939; 6FO62043WK; DSSTox_RID_82047; DSSTox_CID_27006; DSSTox_GSID_47006; Glycyram; alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-
Indication
Disease Entry ICD 11 Status REF
Influenza virus infection 1E30-1E32 Phase 3 [1]
Cross-matching ID
PubChem CID
14982
ChEBI ID
CHEBI:15939
CAS Number
CAS 1405-86-3
TTD Drug ID
DM8M2N3
VARIDT Drug ID
DR00914
INTEDE Drug ID
DR0786

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Clinical Trial Drug(s)
Approved Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BVT.2733 DM6RUKX Lupus 4A40 Phase 3 [10]
INCB13739 DMLQ3PO Type-2 diabetes 5A11 Phase 2a [11]
URSOLIC ACID DM4SOAW Metabolic syndrome x 5C50-5D2Z Phase 2 [12]
JTT-654 DM50M2R Type-2 diabetes 5A11 Phase 2 [13]
RG-4929 DMT4QRD Metabolic disorder 5C50-5D2Z Phase 2 [13]
BMS-770767 DMTVGY7 Hypercholesterolaemia 5C80.0 Phase 2 [13]
UE-2343 DMIERPK Alzheimer disease 8A20 Phase 2 [14]
AZD-4017 DML9M5S Ocular hypertension 9C61.01 Phase 2 [13]
Xanamem DM580GT Alzheimer disease 8A20 Phase 1/2 [15]
BMS-816336 DM2WMJ7 Lipid metabolism disorder 5C52.Z Phase 1 [16]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Methotrexate DM2TEOL Anterior urethra cancer Approved [18]
Folic Acid DMEMBJC Colorectal carcinoma Approved [19]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [20]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [21]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [22]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [23]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [24]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [25]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [26]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Folic Acid DMEMBJC Colorectal carcinoma Approved [28]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [29]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [30]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [31]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [32]
Morphine DMRMS0L Advanced cancer 2A00-2F9Z Approved [33]
Cefadroxil DMMC345 Bacterial infection 1A00-1C4Z Approved [34]
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [35]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [36]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [41]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [42]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [43]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [44]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [38]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [59]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [60]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [61]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [62]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [63]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [63]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [64]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [65]
Capsaicin DMGMF6V Back pain ME84.Z Approved [66]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [67]
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Drug(s) Metabolized By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [46]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [47]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [48]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [50]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [51]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [52]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [53]
Verapamil DMA7PEW Angina pectoris BA40 Approved [54]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [49]
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Drug(s) Metabolized By Cytochrome P450 3A7 (CYP3A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [55]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [49]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [49]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [56]
Verapamil DMA7PEW Angina pectoris BA40 Approved [57]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [49]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [49]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [49]
Metronidazole DMTIVEN Abscess Approved [58]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [68]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [68]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [69]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [71]
Etidronic acid DM1XHYJ Bone Paget disease Approved [68]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [68]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [68]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [72]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [73]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [74]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [9]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [9]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [75]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [74]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [9]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [76]
Gefitinib DM15F0X Colon adenocarcinoma Approved [74]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [77]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [74]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [79]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [80]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [81]
Leflunomide DMR8ONJ Arthritis FA20 Approved [82]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [85]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [86]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [87]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Renin (REN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [88]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [89]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [90]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [91]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [92]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [93]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [94]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [95]
Epinephrine DM3KJBC Acute asthma CA23 Approved [96]
Chlorthalidone DM4DMBT Edema MG29 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [98]
Methotrexate DM2TEOL Anterior urethra cancer Approved [99]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [102]
Paclitaxel DMLB81S Breast carcinoma Approved [103]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [104]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [106]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [107]
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Drug(s) Affected By Androgen receptor (AR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [108]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [108]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [108]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [109]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [110]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [111]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [7]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [112]
Selenium DM25CGV N. A. N. A. Approved [113]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [114]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [115]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [116]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [117]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [118]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [119]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Verapamil DMA7PEW Angina pectoris BA40 Approved [121]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [122]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [123]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [124]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [125]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [126]
Selenium DM25CGV N. A. N. A. Approved [127]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [128]
Methotrexate DM2TEOL Anterior urethra cancer Approved [129]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [130]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [135]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [136]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [137]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [138]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [142]
Panobinostat DM58WKG Chronic graft versus host disease Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [144]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [145]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [124]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [146]
Gefitinib DM15F0X Colon adenocarcinoma Approved [147]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [148]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [149]
Selenium DM25CGV N. A. N. A. Approved [150]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [151]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [153]
Diazepam DM08E9O Alcohol withdrawal Approved [154]
Quercetin DM3NC4M Obesity 5B81 Approved [155]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [156]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [157]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [158]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [159]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [161]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [154]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [163]
Quercetin DM3NC4M Obesity 5B81 Approved [132]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [164]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [165]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Testosterone DM7HUNW Hot flushes GA30 Approved [167]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [167]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [168]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [169]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [170]
Gefitinib DM15F0X Colon adenocarcinoma Approved [171]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [148]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [172]
Etretinate DM2CZFA Keratosis ED56 Approved [173]
Prednisone DM2HG4X Acute asthma CA23 Approved [174]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [175]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [177]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [178]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [179]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [102]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [180]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [182]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [183]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [184]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [187]
Propranolol DM79NTF Angina pectoris BA40 Approved [188]
Testosterone DM7HUNW Hot flushes GA30 Approved [159]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [190]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [192]
Mebendazole DMO14SG Ascariasis 1F62 Approved [193]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [194]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [195]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [122]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [196]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [197]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [198]
Meloxicam DM2AR7L Arthritis FA20 Approved [199]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [200]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [201]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [202]
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [204]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [205]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [206]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [80]
Testosterone DM7HUNW Hot flushes GA30 Approved [167]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [207]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [167]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein jagged-1 (JAG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [209]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [210]
Leflunomide DMR8ONJ Arthritis FA20 Approved [82]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [211]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [190]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [212]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [115]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [185]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Verapamil DMA7PEW Angina pectoris BA40 Approved [121]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [135]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [196]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [148]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [213]
Meloxicam DM2AR7L Arthritis FA20 Approved [214]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [155]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [215]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [216]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [211]
Testosterone enanthate DMB6871 N. A. N. A. Approved [217]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [161]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [218]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [219]
Ethanol DMDRQZU Chronic pain MG30 Approved [220]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [86]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Selenium DM25CGV N. A. N. A. Approved [150]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
Testosterone DM7HUNW Hot flushes GA30 Approved [159]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [167]
Leflunomide DMR8ONJ Arthritis FA20 Approved [82]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [189]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [223]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [224]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [225]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [226]
Gefitinib DM15F0X Colon adenocarcinoma Approved [227]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [228]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [198]
Selenium DM25CGV N. A. N. A. Approved [150]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [200]
Methotrexate DM2TEOL Anterior urethra cancer Approved [99]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [229]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [185]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [226]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [230]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [231]
Quercetin DM3NC4M Obesity 5B81 Approved [232]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [233]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [234]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [235]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Corticosteroid 11-beta-dehydrogenase 1 (HSD11B1) TTN7BL9 DHI1_HUMAN Inhibitor [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 3 (ABCC3) DTQ3ZHF MRP3_HUMAN Substrate [3]
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [4]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [5]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [5]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [6]
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Protein Interaction/Cellular Processes [7]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [8]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [8]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Gene/Protein Processing [8]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Gene/Protein Processing [9]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [8]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [8]

References

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