Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRJKIV)

Drug Name
Caffeic acid phenethyl ester Drug Info
Synonyms
Caffeic acid phenethyl ester; Phenethyl caffeate; 104594-70-9; CAPE; phenethyl 3-(3,4-dihydroxyphenyl)acrylate; Capeee; Phenylethyl caffeate; 115610-29-2; caffeic acid phenylethyl ester; UNII-G960R9S5SK; 2-phenylethyl caffeate; PHENETHYL CAFFEATE (CAPE); Caffeic acid-phenethyl ester; CHEBI:8062; G960R9S5SK; CHEMBL319244; 100981-80-4; Caffeic acid 2-phenylethyl ester; SWUARLUWKZWEBQ-VQHVLOKHSA-N; 2-phenylethyl 3-(3,4-dihydroxyphenyl)-2-propenoate; Caffeic Acid Phenethyl Ester, Synthetic; 2-Phenylethyl (2e)-3-(3,4-Dihydroxyphenyl
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5281787
ChEBI ID
CHEBI:8062
CAS Number
CAS 115610-29-2
TTD Drug ID
DMRJKIV
INTEDE Drug ID
DR2154

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Nuclear factor NF-kappa-B (NFKB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [9]
Triptolide DMCMDVR Autoimmune diabetes 5A10 Phase 3 [10]
Laquinimod DM3IWS8 Lupus 4A40 Phase 3 [11]
Edasalonexent DMYVBF6 Duchenne dystrophy 8C70 Phase 3 [12]
MD1003 DMVZ57G Multiple sclerosis 8A40 Phase 3 [12]
Vadimezan DMK7CYX Solid tumour/cancer 2A00-2F9Z Phase 2 [13]
CAT 1004 DMQBP7R Duchenne dystrophy 8C70 Phase 2 [14]
Parthenolide DMCQBFT N. A. N. A. Phase 2 [15]
Recoflavone DMCSR8I Inflammatory bowel disease DD72 Phase 2 [16]
CZEN-002 DMUDMHA Fungal infection 1F29-1F2F Phase 2 [17]
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Drug(s) Metabolized By Amylosucrase (AMS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
7,8,4'-trihydroxyisoflavone DM80GFL Discovery agent N.A. Investigative [18]
Drug(s) Affected By Aldo-keto reductase family 1 member B10 (AKR1B10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [19]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [20]
Quercetin DM3NC4M Obesity 5B81 Approved [21]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [22]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [23]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [24]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [25]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [26]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [27]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [28]
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Drug(s) Affected By Aldo-keto reductase family 1 member B1 (AKR1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [21]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [31]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [32]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [34]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [35]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [28]
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Drug(s) Affected By Aldo-keto reductase family 1 member C4 (AKR1C4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [5]
Diazepam DM08E9O Alcohol withdrawal Approved [36]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
Benzbromarone DMC3YUA Gout FA25 Approved [38]
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [38]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Nitrazepam DMEGIQ6 Epilepsy 8A60-8A68 Approved [36]
Flunitrazepam DMGR5Z3 Insomnia 7A00-7A0Z Approved [36]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [39]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [40]
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Drug(s) Affected By Aldo-keto reductase family 1 member C3 (AKR1C3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [41]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [42]
Diazepam DM08E9O Alcohol withdrawal Approved [36]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [43]
Desogestrel DM27U4Y Contraception QA21 Approved [43]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [42]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [42]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [44]
Quercetin DM3NC4M Obesity 5B81 Approved [45]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
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Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [42]
Diazepam DM08E9O Alcohol withdrawal Approved [36]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [48]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [42]
Quercetin DM3NC4M Obesity 5B81 Approved [21]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [49]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [42]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [50]
Testosterone DM7HUNW Hot flushes GA30 Approved [51]
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Drug(s) Affected By Aldo-keto reductase family 1 member C1 (AKR1C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [52]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [42]
Diazepam DM08E9O Alcohol withdrawal Approved [36]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [53]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [42]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [42]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [54]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [55]
Ethacrynic acid DM60QMR Edema MG29 Approved [53]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [42]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [57]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [58]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Selenium DM25CGV N. A. N. A. Approved [60]
Etretinate DM2CZFA Keratosis ED56 Approved [61]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [62]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [54]
Quercetin DM3NC4M Obesity 5B81 Approved [64]
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Drug(s) Affected By Monocyte differentiation antigen CD14 (CD14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [65]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [70]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [71]
Testosterone DM7HUNW Hot flushes GA30 Approved [72]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [73]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [37]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [74]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [76]
Verapamil DMA7PEW Angina pectoris BA40 Approved [77]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [78]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [79]
Selenium DM25CGV N. A. N. A. Approved [80]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [81]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
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Drug(s) Affected By Retinoic acid receptor alpha (RARA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [83]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [84]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [85]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [86]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [86]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethanol DMDRQZU Chronic pain MG30 Approved [89]
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Drug(s) Affected By Integrin alpha-M (ITGAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [93]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [94]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [95]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [96]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [97]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [98]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [99]
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Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [57]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [100]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Selenium DM25CGV N. A. N. A. Approved [60]
Etretinate DM2CZFA Keratosis ED56 Approved [61]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [101]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [102]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [103]
Methotrexate DM2TEOL Anterior urethra cancer Approved [104]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [106]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [107]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [108]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [109]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [110]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [111]
Gefitinib DM15F0X Colon adenocarcinoma Approved [112]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [113]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [114]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [115]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [106]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [116]
Paclitaxel DMLB81S Breast carcinoma Approved [117]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [118]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [119]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [120]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [108]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [109]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [121]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [122]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [124]
Gefitinib DM15F0X Colon adenocarcinoma Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [127]
Selenium DM25CGV N. A. N. A. Approved [128]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [129]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [130]
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Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [131]
Folic Acid DMEMBJC Colorectal carcinoma Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [134]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [135]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [136]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [137]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [138]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [139]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [139]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [140]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [141]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [100]
Gefitinib DM15F0X Colon adenocarcinoma Approved [142]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [143]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Etretinate DM2CZFA Keratosis ED56 Approved [61]
Prednisone DM2HG4X Acute asthma CA23 Approved [144]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [101]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [145]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [146]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [147]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [148]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [150]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [151]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [152]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [153]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [154]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [155]
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Drug(s) Affected By Breast cancer anti-estrogen resistance protein 1 (BCAR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [84]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [32]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [33]
Benzatropine DMF7EXL Parkinsonian disorder Approved [156]
Clozapine DMFC71L Schizophrenia 6A20 Approved [156]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [157]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [158]
Arsenic DMTL2Y1 N. A. N. A. Approved [159]
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Drug(s) Affected By Claudin-2 (CLDN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [160]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [162]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [162]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [164]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [35]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [165]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [166]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [167]
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Drug(s) Affected By Focal adhesion kinase 1 (PTK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [110]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [168]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [54]
Quercetin DM3NC4M Obesity 5B81 Approved [169]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [170]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [171]
Testosterone DM7HUNW Hot flushes GA30 Approved [172]
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [173]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [27]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [174]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [175]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [155]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [160]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [176]
Methotrexate DM2TEOL Anterior urethra cancer Approved [63]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [46]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [177]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [178]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [179]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [175]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [155]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [180]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [181]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [182]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [183]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [184]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [179]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [185]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [186]
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Drug(s) Affected By CCAAT/enhancer-binding protein epsilon (CEBPE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [187]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Leflunomide DMR8ONJ Arthritis FA20 Approved [189]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [158]
Pomalidomide DMTGBAX Plasma cell myeloma 2A83.1 Approved [190]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [191]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [192]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [193]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [194]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Nuclear factor NF-kappa-B (NFKB) TTSXVID NFKB1_HUMAN; NFKB2_HUMAN; TF65_HUMAN; RELB_HUMAN; REL_HUMAN Inhibitor [1]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Dextransucrase 4 (dsrF4) DE1KTC4 GTF4_LEUME Substrate [2]
Dextransucrase 3 (dsrF3) DED68N5 GTF3_LEUME Substrate [2]
Dextransucrase 2 (dsrF2) DE174E0 GTF2_LEUME Substrate [2]
Dextransucrase 1 (dsrF1) DEEPQJ8 GTF1_LEUME Substrate [2]
Amylosucrase (AMS) DEEZYQV Q1J0W0_DEIGD Substrate [3] , [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Aldo-keto reductase family 1 member B1 (AKR1B1) OTRX72TH ALDR_HUMAN Gene/Protein Processing [5]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Gene/Protein Processing [5]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Gene/Protein Processing [5]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Gene/Protein Processing [5]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Gene/Protein Processing [5]
Aldo-keto reductase family 1 member C4 (AKR1C4) OTW2MMOF AK1C4_HUMAN Gene/Protein Processing [5]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Gene/Protein Processing [6]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Gene/Protein Processing [6]
Breast cancer anti-estrogen resistance protein 1 (BCAR1) OTKT2C2N BCAR1_HUMAN Post-Translational Modifications [7]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [8]

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