Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMU8L7C)

Drug Name
Mepacrine Drug Info
Synonyms
quinacrine; mepacrine; atabrine; Acrinamine; Acriquine; 83-89-6; Quinactine; Antimalarina; Haffkinine; Akrichin; Italchine; acrichine; Erion; Mepacrinum; Quinacrine hydrochloride; Mepacrine [INN:BAN]; St 439; Mepacrinum [INN-Latin]; Mepacrina [INN-Spanish]; atebrin; Malaricida; Methoquine; Palacrin; Italchin; Pentilen; Palusan; Atebrine; Metochin; Mecryl; Quinacrine, Mepacrine; 3-Chloro-7-methoxy-9-(1-methyl-4-diethylaminobutylamino)acridine; 2-Methoxy-6-chloro-9-diethylaminopentylaminoacridine; HSDB 3253
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
237
ChEBI ID
CHEBI:8711
CAS Number
CAS 83-89-6
TTD Drug ID
DMU8L7C
VARIDT Drug ID
DR01478
INTEDE Drug ID
DR1377

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Phospholipase A2 (PLA2G1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [9]
Miltefosine DMND304 Chronic urticaria Approved [10]
Clocortolone DM9ZMQH Exanthem Approved [11]
Clobetasol DMUXP52 Rosacea ED90.0 Approved [12]
Diflorasone DMI9PRJ Exanthem Approved [13]
AllerB DM78DOT Allergy 4A80-4A85 Phase 2b [14]
URSOLIC ACID DM4SOAW Metabolic syndrome x 5C50-5D2Z Phase 2 [15]
MANOALIDE DMB4A8I Arthritis FA20 Phase 2 [16]
MRX-4 DMQZWYE Allergic rhinitis CA08.0 Phase 2 [17]
MRX-6 DMLVQKF Contact dermatitis EK0Z Phase 2 [18]
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Drug(s) Transported By Breast cancer resistance protein (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [19]
Methotrexate DM2TEOL Anterior urethra cancer Approved [20]
Folic Acid DMEMBJC Colorectal carcinoma Approved [21]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [22]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [23]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [24]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [25]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [24]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [26]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [27]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [29]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [30]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [31]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [32]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [33]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [34]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [35]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [29]
Verapamil DMA7PEW Angina pectoris BA40 Approved [36]
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Drug(s) Metabolized By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [37]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [38]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [40]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [41]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [42]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [44]
Verapamil DMA7PEW Angina pectoris BA40 Approved [45]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [40]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [46]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [47]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [48]
Gefitinib DM15F0X Colon adenocarcinoma Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [50]
Selenium DM25CGV N. A. N. A. Approved [51]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [52]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [53]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [54]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [56]
Methotrexate DM2TEOL Anterior urethra cancer Approved [55]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [58]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [59]
Paclitaxel DMLB81S Breast carcinoma Approved [60]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [62]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [63]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [64]
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Drug(s) Affected By Zinc finger protein GLI1 (GLI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [70]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [71]
Arsenic DMTL2Y1 N. A. N. A. Approved [72]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [73]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [74]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Gefitinib DM15F0X Colon adenocarcinoma Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [78]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [79]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [80]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [79]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [81]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [83]
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Drug(s) Affected By 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [84]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [85]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [86]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [91]
Arsenic DMTL2Y1 N. A. N. A. Approved [92]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [93]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [94]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [95]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [96]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [97]
Gefitinib DM15F0X Colon adenocarcinoma Approved [98]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Selenium DM25CGV N. A. N. A. Approved [101]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [52]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [102]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [103]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [104]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [105]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [106]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [107]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [108]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [109]
Gefitinib DM15F0X Colon adenocarcinoma Approved [110]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [111]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [112]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [113]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [104]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [114]
Paclitaxel DMLB81S Breast carcinoma Approved [115]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [116]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [103]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [117]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [118]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [106]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [107]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [119]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [124]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [125]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [126]
Testosterone DM7HUNW Hot flushes GA30 Approved [127]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [128]
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Drug(s) Affected By Vascular endothelial growth factor receptor 2 (KDR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [129]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [130]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [131]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [132]
Haloperidol DM96SE0 Delirium Approved [84]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
Clozapine DMFC71L Schizophrenia 6A20 Approved [84]
Menthol DMG2KW7 Back pain ME84.Z Approved [135]
Orlistat DMRJSP8 Obesity 5B81 Approved [136]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [137]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [138]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [139]
Gefitinib DM15F0X Colon adenocarcinoma Approved [140]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [141]
Etretinate DM2CZFA Keratosis ED56 Approved [142]
Prednisone DM2HG4X Acute asthma CA23 Approved [143]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [80]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [144]
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Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [145]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [146]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [147]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [59]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [148]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [149]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [153]
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Drug(s) Affected By Casein kinase I isoform alpha (CSNK1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [101]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [154]
Leflunomide DMR8ONJ Arthritis FA20 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [156]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [70]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [157]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [158]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [159]
Gefitinib DM15F0X Colon adenocarcinoma Approved [160]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [161]
Selenium DM25CGV N. A. N. A. Approved [101]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [162]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [163]
Quercetin DM3NC4M Obesity 5B81 Approved [164]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [165]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [166]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [167]
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Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [168]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [169]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [170]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [171]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [172]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [78]
Meloxicam DM2AR7L Arthritis FA20 Approved [173]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [174]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [175]
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Drug(s) Affected By Focal adhesion kinase 1 (PTK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [108]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [176]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [181]
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [182]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [134]
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Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [183]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [153]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Verapamil DMA7PEW Angina pectoris BA40 Approved [184]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [185]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [171]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [99]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Meloxicam DM2AR7L Arthritis FA20 Approved [186]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [80]
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Drug(s) Affected By Potassium voltage-gated channel subfamily H member 2 (KCNH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Metoclopramide DMFA5MY Nausea MD90 Approved [187]
Quinidine DMLPICK N. A. N. A. Approved [188]
Verapamil DMA7PEW Angina pectoris BA40 Approved [189]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [190]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [190]
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [191]
Propranolol DM79NTF Angina pectoris BA40 Approved [192]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [193]
Dofetilide DMPN1TW Sinus rhythm disorder BC9Y Approved [194]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [190]
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Drug(s) Affected By Forkhead box protein P3 (FOXP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [195]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [196]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [197]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [198]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [199]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [200]
GSK618334 DMJPXZ4 Drug abuse 6C4G.1Z Phase 1 [201]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [202]
Dorsomorphin DMKYXJW Discovery agent N.A. Investigative [203]
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Drug(s) Affected By F-box/WD repeat-containing protein 1A (BTRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [204]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [205]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [206]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [207]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [206]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [208]
Calphostin C DM9X2D0 N. A. N. A. Terminated [209]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [195]
Milchsaure DM462BT Pruritus EC90 Investigative [210]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [211]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [212]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [213]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [214]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [215]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [216]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [217]
Ethacrynic acid DM60QMR Edema MG29 Approved [218]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [219]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [220]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [221]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [222]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [223]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [224]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [225]
Cepharanthine DM9Y5JB N. A. N. A. Approved [226]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [227]
Clozapine DMFC71L Schizophrenia 6A20 Approved [228]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [229]
Trifluoperazine DMKBYWI Anxiety Approved [230]
Olanzapine DMPFN6Y Bipolar depression Approved [228]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Phospholipase A2 (PLA2G1B) TT9V5JH PA21B_HUMAN Inhibitor [1]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [2]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [3]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [3]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 (PLCG1) OTSBQR6D PLCG1_HUMAN Post-Translational Modifications [4]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [5]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Regulation of Drug Effects [3]
Casein kinase I isoform alpha (CSNK1A1) OTJ6O1IC KC1A_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [6]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Protein Interaction/Cellular Processes [5]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [6]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [7]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [8]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Regulation of Drug Effects [3]

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