Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMZ0Q1G)

Drug Name
Permethrin Drug Info
Synonyms
Ambush; PerFoam; Transpermethrin; Acticin Cream; Elimite Cream; Nix Cream Rinse; Transpermethrin [ISO];FMC 35171; NRDC 146; NRDC 148; PS758_SUPELCO; Permethrin (isomers); Permethrin (isomers) solution; Permethrine,c&t; Trans-(+-)-Permethrin; [3-(phenyloxy)phenyl]methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; (+)-CIS-PERMETHRIN; (+)-trans-Permethrin; (+-)-cis-Fmc 33297; (+-)-cis-Permethrin; (+-)-trans-Permethrin; (3-Phenoxyphenyl)methyl (+-)-cis,trans-3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate; (3-phenoxyphenyl)methyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropane-1-carboxylate; 1RS,cis-Permethrin; 1RS-trans-Permethrin; 3-Phenoxybenzyle (1RS)-cis, trans-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropane carboxylate; 3-phenoxybenzyl 3-(2,2-dichloroethenyl)-2,2-dimethylcyclopropanecarboxylate
Indication
Disease Entry ICD 11 Status REF
Pediculus capitis infestation 1G00.0 Approved [1]
Pediculus humanus corporis infestation Approved [1]
Pthirus pubis infestation Approved [1]
Sarcoptes scabiei infection 1G04 Approved [2]
Therapeutic Class
Insecticides
Cross-matching ID
PubChem CID
40326
ChEBI ID
CHEBI:34911
CAS Number
CAS 52645-53-1
TTD Drug ID
DMZ0Q1G
INTEDE Drug ID
DR1262
ACDINA Drug ID
D01337

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Preclinical Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Sodium channel unspecific (NaC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [7]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [8]
Zonisamide DM0DTF7 Alcohol dependence 6C40.2 Approved [9]
Eslicarbazepine DMZREFQ Seizure disorder 8A6Z Approved [10]
LIDOFLAZINE DMV23GL Angina pectoris BA40 Approved [11]
LOMERIZINE DME0TC8 Migraine 8A80 Approved [12]
Levobupivacaine DM783CH Anaesthesia 9A78.6 Approved [13]
Tetrodotoxin DMWMPRG Bacterial infection 1A00-1C4Z Approved [14]
Rufinamide DMWE60C Epilepsy 8A60-8A68 Approved [15]
Butacaine DM584TM Pain MG30-MG3Z Approved [16]
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Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [17]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [18]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [19]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [20]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [21]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [22]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [23]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [24]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [18]
Verapamil DMA7PEW Angina pectoris BA40 Approved [25]
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [36]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [39]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [40]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [41]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [42]
Capsaicin DMGMF6V Back pain ME84.Z Approved [43]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [44]
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Drug(s) Metabolized By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [26]
Verapamil DMA7PEW Angina pectoris BA40 Approved [27]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [28]
Estrone DM5T6US Acne vulgaris ED80 Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [30]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [31]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [32]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [33]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [34]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [35]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [45]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [46]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [47]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [48]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [49]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [50]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [51]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [52]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [53]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [54]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [55]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [55]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [58]
Etidronic acid DM1XHYJ Bone Paget disease Approved [55]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [55]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [55]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [59]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [60]
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Drug(s) Affected By Adenylate kinase isoenzyme 1 (AK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [61]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [61]
Anastrozole DMNP60F Breast cancer 2C60-2C65 Approved [61]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [61]
Selenium DM25CGV N. A. N. A. Approved [62]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Benzatropine DMF7EXL Parkinsonian disorder Approved [65]
Clozapine DMFC71L Schizophrenia 6A20 Approved [65]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [67]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [68]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [69]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [70]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [71]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [72]
Ethacrynic acid DM60QMR Edema MG29 Approved [73]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [74]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [75]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [76]
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Drug(s) Affected By Cytochrome P450 2A6 (CYP2A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [77]
Methoxsalen DME8FZ9 Cutaneous T-cell lymphoma 2B01 Approved [78]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [80]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [20]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [83]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [84]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [85]
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Drug(s) Affected By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [36]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [42]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [42]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [86]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [87]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [88]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [91]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [92]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [92]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [92]
Capsaicin DMGMF6V Back pain ME84.Z Approved [93]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [94]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [95]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [96]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [97]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [98]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [61]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 3 (NR1I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [59]
Quercetin DM3NC4M Obesity 5B81 Approved [99]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [100]
Artemether DM48QOT Malaria 1F40-1F45 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [103]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [104]
Estrone DM5T6US Acne vulgaris ED80 Approved [105]
Leflunomide DMR8ONJ Arthritis FA20 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
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Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [107]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [107]
Gefitinib DM15F0X Colon adenocarcinoma Approved [108]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [61]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [109]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [110]
Methotrexate DM2TEOL Anterior urethra cancer Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [114]
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Drug(s) Affected By Shootin-1 (SHTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [120]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
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Drug(s) Affected By Protein shisa-3 homolog (SHISA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ethanol DMDRQZU Chronic pain MG30 Approved [124]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
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Drug(s) Affected By Transmembrane protein 72 (TMEM72)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Arsenic DMTL2Y1 N. A. N. A. Approved [130]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Drug(s) Affected By Colipase-like protein 1 (CLPSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Regulator of G-protein signaling protein-like (RGSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Transmembrane protein 247 (TMEM247)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Drug(s) Affected By Oocyte-expressed protein homolog (OOEP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Calpain-8 (CAPN8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
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Drug(s) Affected By Alpha-2-macroglobulin-like protein 1 (A2ML1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By Small integral membrane protein 22 (SMIM22)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Drug(s) Affected By Sulfotransferase 1C2 (SULT1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [145]
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Drug(s) Affected By Nck-associated protein 5 (NCKAP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
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Drug(s) Affected By Transmembrane gamma-carboxyglutamic acid protein 1 (PRRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [151]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 11 (TNFSF11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Methotrexate DM2TEOL Anterior urethra cancer Approved [154]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [155]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [156]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [158]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
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Drug(s) Affected By Serine/threonine-protein phosphatase with EF-hands 1 (PPEF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [162]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
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Drug(s) Affected By Group 10 secretory phospholipase A2 (PLA2G10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [89]
Rutin DMEHRAJ Discovery agent N.A. Investigative [165]
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Drug(s) Affected By Regulator of G-protein signaling 5 (RGS5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [166]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [168]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [142]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [169]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
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Drug(s) Affected By Maltase-glucoamylase (MGAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [121]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [171]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [173]
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Drug(s) Affected By Beta-1,3-galactosyltransferase 2 (B3GALT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Lead acetate DML0GZ2 Discovery agent N.A. Investigative [174]
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Drug(s) Affected By Carbohydrate sulfotransferase 1 (CHST1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [175]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Ibrolipim DMOPWSX Hyperlipidaemia 5C80 Phase 2 [176]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kallikrein-8 (KLK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Potassium Chloride DMMTAJC Hypokalemia 5C77 Approved [178]
Arsenic DMTL2Y1 N. A. N. A. Approved [175]
Magnesium DMU4ORS Ischemic stroke 8B11.5Z Approved [178]
Magnesium Sulfate DMVEK07 Acute pain MG31 Approved [178]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [120]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tudor domain-containing protein 6 (TDRD6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [89]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 9 (ABCC9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [182]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [61]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding motif protein, X-linked-like-2 (RBMXL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Ret finger protein-like 2 (RFPL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Gap junction beta-3 protein (GJB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [183]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Sulfotransferase 1C4 (SULT1C4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [140]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [185]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Olfactory receptor 2J2 (OR2J2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Phospholipid-transporting ATPase VB (ATP10B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [187]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Neurofascin (NFASC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Angiopoietin-related protein 1 (ANGPTL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tetraspanin-15 (TSPAN15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [192]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 17 (PPP1R17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [193]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [193]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [194]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Ceruloplasmin (CP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [196]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [197]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [198]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Ampicillin DMHWE7P Acute epiglottitis Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen (PLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [199]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [200]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [201]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [89]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [202]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [204]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [204]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [205]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [204]
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Quercetin DM3NC4M Obesity 5B81 Approved [207]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [204]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [72]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polymeric immunoglobulin receptor (PIGR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Arsenic DMTL2Y1 N. A. N. A. Approved [208]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [209]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [210]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [211]
Gefitinib DM15F0X Colon adenocarcinoma Approved [212]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [213]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [214]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [215]
Quercetin DM3NC4M Obesity 5B81 Approved [216]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [217]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [213]
Estrone DM5T6US Acne vulgaris ED80 Approved [218]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [219]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [220]
Haloperidol DM96SE0 Delirium Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [221]
Selenium DM25CGV N. A. N. A. Approved [222]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [223]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [224]
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [225]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Trefoil factor 1 (TFF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [226]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [228]
Quercetin DM3NC4M Obesity 5B81 Approved [229]
Estrone DM5T6US Acne vulgaris ED80 Approved [230]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [231]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [228]
Testosterone DM7HUNW Hot flushes GA30 Approved [232]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Receptor tyrosine-protein kinase erbB-2 (ERBB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trastuzumab DMZQOUX Breast cancer 2C60-2C65 Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [234]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [235]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [236]
Gefitinib DM15F0X Colon adenocarcinoma Approved [237]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [238]
Selenium DM25CGV N. A. N. A. Approved [62]
Methotrexate DM2TEOL Anterior urethra cancer Approved [239]
Quercetin DM3NC4M Obesity 5B81 Approved [240]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon alpha-6 (IFNA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [241]
Drug(s) Affected By Myosin light chain 1/3, skeletal muscle isoform (MYL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Clozapine DMFC71L Schizophrenia 6A20 Approved [65]
Norepinephrine DMOUC09 Alopecia ED70 Approved [242]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Deguelin DMXT7WG Esophageal squamous cell carcinoma 2E60.1 Investigative [194]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Carbonic anhydrase 3 (CA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [243]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [244]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
BICARBONATE DMT5E36 Discovery agent N.A. Investigative [245]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Kappa-casein (CSN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Decorin (DCN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [205]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [246]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [247]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [248]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Folic Acid DMEMBJC Colorectal carcinoma Approved [249]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pulmonary surfactant-associated protein B (SFTPB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Terbutaline DMD4381 Asthma CA23 Approved [251]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [251]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [252]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [253]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [252]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [252]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein Hox-B5 (HOXB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [254]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Arsenic DMTL2Y1 N. A. N. A. Approved [255]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [256]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [257]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [244]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Matrilysin (MMP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [239]
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [259]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [260]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [261]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [262]
Clozapine DMFC71L Schizophrenia 6A20 Approved [263]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [264]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon-induced protein with tetratricopeptide repeats 1 (IFIT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [265]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [266]
Testosterone DM7HUNW Hot flushes GA30 Approved [267]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [268]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Androgen receptor (AR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [269]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [269]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [269]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [270]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [271]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [272]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [273]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [274]
Selenium DM25CGV N. A. N. A. Approved [275]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [276]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [277]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [278]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [279]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [280]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Verapamil DMA7PEW Angina pectoris BA40 Approved [281]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [282]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [283]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [284]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Receptor-type tyrosine-protein phosphatase F (PTPRF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [285]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eosinophil peroxidase (EPX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [285]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [287]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [288]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [285]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Butanoic Acid DMTAJP7 Discovery agent N.A. Investigative [289]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Desmoplakin (DSP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [290]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [291]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [292]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (PFKFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [293]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [142]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [294]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [89]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [89]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Integrin beta-6 (ITGB6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [238]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Paclitaxel DMLB81S Breast carcinoma Approved [296]
Bortezomib DMNO38U Leukemia Approved [297]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [298]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [299]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
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Drug(s) Affected By Gastricsin (PGC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [300]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ampicillin DMHWE7P Acute epiglottitis Approved [140]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kit ligand (KITLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [301]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Quercetin DM3NC4M Obesity 5B81 Approved [207]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [302]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [303]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor receptor 2 (FGFR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [304]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [305]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [302]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [306]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [306]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [192]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By B-cell differentiation antigen CD72 (CD72)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Rigosertib DMOSTXF Myelodysplastic syndrome 2A37 Phase 3 [307]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [308]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
Drug(s) Affected By Vitamin K-dependent protein Z (PROZ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [294]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
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Drug(s) Affected By Brain-derived neurotrophic factor (BDNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [309]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [310]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [311]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Bupivacaine DM4PRFC Anaesthesia 9A78.6 Approved [312]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [313]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endothelin receptor type B (EDNRB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [314]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [315]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Ethanol DMDRQZU Chronic pain MG30 Approved [317]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [318]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [319]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [320]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [321]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [322]
Methotrexate DM2TEOL Anterior urethra cancer Approved [323]
Epinephrine DM3KJBC Acute asthma CA23 Approved [324]
Quercetin DM3NC4M Obesity 5B81 Approved [325]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [326]
Fructose DM43AN2 Vomiting MD90 Approved [327]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [320]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [328]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [329]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [330]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [331]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [283]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [332]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [333]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [334]
Gefitinib DM15F0X Colon adenocarcinoma Approved [335]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [336]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [337]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Embryonic growth/differentiation factor 1 (GDF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [338]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [339]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [340]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [339]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
PHENCYCLIDINE DMQBEYX Discovery agent N.A. Investigative [341]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(VIII) chain (COL8A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [294]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [342]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [343]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [330]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [344]
Paclitaxel DMLB81S Breast carcinoma Approved [345]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [346]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [329]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [61]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [347]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [283]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [332]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysine-specific demethylase 5A (KDM5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [348]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Ethanol DMDRQZU Chronic pain MG30 Approved [349]
Menthol DMG2KW7 Back pain ME84.Z Approved [350]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leiomodin-1 (LMOD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [351]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [352]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [182]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [62]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [353]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (PDHA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Somatostatin receptor type 2 (SSTR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pasireotide DMHM7JS Cushing disease 5A70 Approved [354]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [355]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Edotreotide DMQ08AJ Acromegaly 5A60.0 Phase 2 [356]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID26394986-Compound-22 DM43Z1G N. A. N. A. Patented [357]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [358]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 4 (MAPK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [359]
IRX4204 DM9SCME Breast cancer 2C60-2C65 Phase 1 [360]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [361]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [362]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Cadherin-5 (CDH5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [363]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [364]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [365]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [142]
Ethanol DMDRQZU Chronic pain MG30 Approved [366]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [367]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [368]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cornifin-A (SPRR1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [369]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [370]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [371]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [372]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
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Drug(s) Affected By Thrombospondin-2 (THBS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [373]
Quercetin DM3NC4M Obesity 5B81 Approved [314]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [374]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [197]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [351]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor SOX-18 (SOX18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [302]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [302]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [140]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Indomethacin DMSC4A7 Bursitis Approved [375]
Arsenic DMTL2Y1 N. A. N. A. Approved [376]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor ETV6 (ETV6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [377]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [378]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [379]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [377]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [380]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
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Drug(s) Affected By Glutamate receptor 1 (GRIA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [381]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [382]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [318]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [169]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [383]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [384]
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Drug(s) Affected By Nuclear receptor subfamily 4 group A member 2 (NR4A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [385]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [386]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [387]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [248]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [121]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [358]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [388]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor GATA-4 (GATA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [389]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [390]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [391]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [392]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [386]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [393]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagenase 3 (MMP13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [394]
Clindamycin DM15HL8 Acne vulgaris ED80 Approved [395]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [394]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [396]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [397]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [398]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Doxycycline DM7ICNU Acne vulgaris ED80 Approved [395]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [399]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [268]
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Drug(s) Affected By Type I iodothyronine deiodinase (DIO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [400]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [381]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [401]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [402]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [401]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [403]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [404]
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Drug(s) Affected By High mobility group protein HMGI-C (HMGA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [405]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [358]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [351]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [406]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [379]
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Drug(s) Affected By Chromaffin granule amine transporter (SLC18A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [61]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [407]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
SEROTONIN DMOFCRY Discovery agent N.A. Investigative [408]
Drug(s) Affected By Period circadian protein homolog 3 (PER3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Selenium DM25CGV N. A. N. A. Approved [62]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [169]
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Drug(s) Affected By Junctional adhesion molecule B (JAM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [405]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [409]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [410]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [411]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [407]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
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Drug(s) Affected By Gap junction alpha-9 protein (GJA9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [320]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [243]
Drug(s) Affected By Taste receptor type 2 member 20 (TAS2R20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [412]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Drug(s) Affected By Major intrinsically disordered NOTCH2-binding receptor 1-like (MINAR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Drug(s) Affected By Myelin proteolipid protein (PLP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Ethanol DMDRQZU Chronic pain MG30 Approved [413]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [414]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [411]
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Drug(s) Affected By Fibulin-2 (FBLN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [314]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [415]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [383]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
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Drug(s) Affected By Runt-related transcription factor 1 (RUNX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [247]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [285]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [197]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [197]
Cotinine DMCEZ1B Insecticide N.A. Approved [416]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
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Drug(s) Affected By Myelin transcription factor 1 (MYT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [417]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [418]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [419]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [418]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [419]
Octanal DMTN0OK N. A. N. A. Investigative [420]
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Drug(s) Affected By Sodium-dependent dopamine transporter (SLC6A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [421]
Amphetamine DMSZQAK Attention deficit hyperactivity disorder 6A05.Z Approved [422]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [423]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [424]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [425]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 4A11 (CYP4A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [426]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [427]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [427]
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [293]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [428]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [428]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [427]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [427]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [427]
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Drug(s) Affected By Histone-lysine N-methyltransferase 2A (KMT2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [429]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [348]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Ethanol DMDRQZU Chronic pain MG30 Approved [349]
Clozapine DMFC71L Schizophrenia 6A20 Approved [430]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [431]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldehyde oxidase (AOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [189]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [265]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [103]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [351]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Binder of sperm protein homolog 1 (BSPH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Uncharacterized protein C17orf67 (C17ORF67)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Drug(s) Affected By Fatty acid-binding protein 9 (FABP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By Prolyl endopeptidase FAP (FAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [432]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
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Drug(s) Affected By Forkhead box protein I1 (FOXI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [433]
Drug(s) Affected By Interleukin-15 receptor subunit alpha (IL15RA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [434]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
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Drug(s) Affected By Urea transporter 1 (SLC14A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [406]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [89]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [415]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [435]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [436]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [437]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GRB2-associated-binding protein 1 (GAB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [438]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Menthol DMG2KW7 Back pain ME84.Z Approved [350]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [406]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [393]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metabotropic glutamate receptor 2 (GRM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Methamphetamine DMPM4SK Anxiety Approved [439]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [440]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
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Drug(s) Affected By Interleukin-13 receptor subunit alpha-2 (IL13RA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [248]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [318]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [441]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [187]
Arsenic DMTL2Y1 N. A. N. A. Approved [442]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [443]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium channel protein type 9 subunit alpha (SCN9A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [444]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Tetrodotoxin DMWMPRG Bacterial infection 1A00-1C4Z Approved [445]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
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Drug(s) Affected By Protein FAM110C (FAM110C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [446]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
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Drug(s) Affected By Keratin-associated protein 27-1 (KRTAP27-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Solute carrier family 9 member C1 (SLC9C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By IQ domain-containing protein C (IQCC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
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Drug(s) Affected By 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [169]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [411]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
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Drug(s) Affected By Angiomotin (AMOT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ethanol DMDRQZU Chronic pain MG30 Approved [413]
Ampicillin DMHWE7P Acute epiglottitis Approved [140]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
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Drug(s) Affected By Sodium/hydrogen exchanger 9B1 (SLC9B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Cation channel sperm-associated targeting subunit tau (C2CD6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Kita-kyushu lung cancer antigen 1 (CT83)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Uncharacterized protein C1orf141 (C1ORF141)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Ephrin type-A receptor 10 (EPHA10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [448]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [448]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [449]
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Drug(s) Affected By Cyclin-dependent kinase-like 4 (CDKL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Drug(s) Affected By Histone H2B type 2-F (H2BC18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [450]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
GALLICACID DM6Y3A0 Discovery agent N.A. Investigative [451]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Interferon-induced protein with tetratricopeptide repeats 1B (IFIT1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Acyl-CoA-binding domain-containing protein 5 (ACBD5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibronectin type III domain-containing protein 7 (FNDC7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Arylacetamide deacetylase-like 4 (AADACL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Mesenteric estrogen-dependent adipogenesis protein (MEDAG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [169]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Phospholipid phosphatase 4 (PLPP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Triple QxxK/R motif-containing protein (TRIQK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [297]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [452]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FERM and PDZ domain-containing protein 2 (FRMPD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [453]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [454]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [453]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
UNC0379 DMD1E4J Hepatocellular carcinoma 2C12.02 Preclinical [455]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 40 (KRT40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Proline-rich protein 27 (PRR27)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Drug(s) Affected By Choriogonadotropin subunit beta variant 2 (CGB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Forskolin DM6ITNG Solid tumour/cancer 2A00-2F9Z Investigative [456]
norfluoxetine DMKNUP3 Discovery agent N.A. Investigative [456]
Drug(s) Affected By Proactivator polypeptide-like 1 (PSAPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By Fanconi anemia core complex-associated protein 20 (FAAP20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [457]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [458]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [459]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Keratin-associated protein 26-1 (KRTAP26-1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Opsin-5 (OPN5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Transmembrane protein 270 (TMEM270)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [460]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [449]
Drug(s) Affected By Surfactant-associated protein 2 (SFTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Serine protease 55 (PRSS55)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Arylsulfatase K (ARSK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [308]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [461]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [462]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By ALK and LTK ligand 2 (ALKAL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [89]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [463]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Butyrophilin-like protein 3 (BTNL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [464]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By CMRF35-like molecule 9 (CD300LG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Protocadherin-23 (DCHS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Neuropeptide S receptor (NPSR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2 (TPTE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tanespimycin DMNLQHK Breast cancer 2C60-2C65 Phase 2 [465]
Scriptaid DM9JZ21 Solid tumour/cancer 2A00-2F9Z Preclinical [466]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Thrombospondin type-1 domain-containing protein 4 (THSD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [381]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [406]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [467]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Death domain-containing protein 1 (DTHD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Protein LEKR1 (LEKR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Cilia- and flagella-associated protein 77 (CFAP77)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By Indoleamine 2,3-dioxygenase 2 (IDO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [468]
Drug(s) Affected By Proline-rich protein 23B (PRR23B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By UPF0606 protein KIAA1549L (KIAA1549L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [469]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [120]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [470]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [142]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [470]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid phosphatase-related protein type 4 (PLPPR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Geldanamycin DMS7TC5 Kidney cancer 2C90.0 Discontinued in Phase 2 [143]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By G protein-regulated inducer of neurite outgrowth 1 (GPRIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [471]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [458]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Transient receptor potential cation channel subfamily M member 8 (TRPM8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Menthol DMG2KW7 Back pain ME84.Z Approved [472]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [473]
Capsaicin DMGMF6V Back pain ME84.Z Approved [472]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [294]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PTB-containing, cubilin and LRP1-interacting protein (PID1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [204]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [204]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [204]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [204]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [204]
Amikacin DM5PDRB Bacteremia 1A73 Approved [204]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [204]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [204]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [204]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein RD3 (RD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
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Drug(s) Affected By Putative ATP synthase subunit g 2, mitochondrial (ATP5MGL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [83]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Drug(s) Affected By Chemokine-like protein TAFA-3 (TAFA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
Drug(s) Affected By FYVE, RhoGEF and PH domain-containing protein 2 (FGD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [457]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Arpin (ARPIN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Arsenic DMTL2Y1 N. A. N. A. Approved [175]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Regulator of DNA class I crossover intermediates 1 (REDIC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [453]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Ras-related protein Rab-43 (RAB43)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [474]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
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Drug(s) Affected By Beta-klotho (KLB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [452]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch domain-containing protein 8A (KLHDC8A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [475]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [449]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stabilizer of axonemal microtubules 1 (SAXO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [162]
Drug(s) Affected By Heparan-sulfate 6-O-sulfotransferase 3 (HS6ST3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [476]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
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Drug(s) Affected By Ligand-dependent nuclear receptor corepressor-like protein (LCORL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
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Drug(s) Affected By Polypeptide N-acetylgalactosaminyltransferase 16 (GALNT16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [197]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [197]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [197]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [452]
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Drug(s) Affected By Inactive carboxypeptidase-like protein X2 (CPXM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [434]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Translocating chain-associated membrane protein 1-like 1 (TRAM1L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By IQ domain-containing protein F1 (IQCF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [477]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Drug(s) Affected By UPF0728 protein C10orf53 (C10ORF53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By POU domain, class 5, transcription factor 2 (POU5F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [241]
Drug(s) Affected By Ankyrin repeat domain-containing protein 31 (ANKRD31)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By Choline transporter-like protein 5 (SLC44A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [358]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [478]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hemicentin-2 (HMCN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Indomethacin DMSC4A7 Bursitis Approved [375]
Arsenic DMTL2Y1 N. A. N. A. Approved [464]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
APR-246 DMNFADH Ovarian cancer 2C73 Phase 2 [479]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
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Drug(s) Affected By Transient receptor potential cation channel subfamily V member 3 (TRPV3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Camphor DMWIO46 Acute or chronic pain MG30-MG31 Approved [480]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Manganese DMKT129 N. A. N. A. Investigative [481]
1,4-Naphthoquinone DMTCMH7 Discovery agent N.A. Investigative [482]
1,2-NAPHTHOQUINONE DMYXELH Discovery agent N.A. Investigative [482]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protein DBF4 homolog B (DBF4B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Olfactory receptor 5D18 (OR5D18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [243]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [483]
Drug(s) Affected By Olfactory receptor 1L8 (OR1L8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Drug(s) Affected By Olfactory receptor 10A6 (OR10A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By Fibronectin type 3 and ankyrin repeat domains protein 1 (FANK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase BRSK1 (BRSK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [294]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [257]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [484]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Biogenesis of lysosome-related organelles complex 1 subunit 5 (BLOC1S5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [297]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Drug(s) Affected By Probable glutathione peroxidase 8 (GPX8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Orlistat DMRJSP8 Obesity 5B81 Approved [485]
Lucanthone DMZLBUO Solid tumour/cancer 2A00-2F9Z Approved [486]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C10orf105 (C10ORF105)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Partitioning defective 3 homolog (PARD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [458]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [315]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Gentamicin DMKINJO Bacteremia 1A73 Approved [315]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein prune homolog 2 (PRUNE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [487]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Connector enhancer of kinase suppressor of ras 2 (CNKSR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [358]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [488]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cationic amino acid transporter 3 (SLC7A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [489]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By CMP-N-acetylneuraminate-poly-alpha-2,8-sialyltransferase (ST8SIA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [410]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rap guanine nucleotide exchange factor 5 (RAPGEF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Paclitaxel DMLB81S Breast carcinoma Approved [490]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [383]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Delta-sarcoglycan (SGCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [143]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Synapsin-2 (SYN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [491]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [116]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [407]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [449]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Gap junction alpha-10 protein (GJA10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Polyadenylate-binding protein 5 (PABPC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [243]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Cysteine and tyrosine-rich protein 1 (CYYR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Ethanol DMDRQZU Chronic pain MG30 Approved [124]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Beta-galactoside alpha-2,6-sialyltransferase 2 (ST6GAL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [169]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Spermatogenesis-associated protein 17 (SPATA17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [406]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [434]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [463]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [362]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coiled-coil domain-containing protein 17 (CCDC17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [468]
Drug(s) Affected By Testis-specific expressed protein 55 (TEX55)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Chloride intracellular channel protein 6 (CLIC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [492]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [492]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [492]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sperm acrosome-associated protein 5 (SPACA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Protocadherin-15 (PCDH15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Chlorothiazide DMLHESP Chronic heart failure BD1Z Approved [493]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [458]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Pannexin-2 (PANX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [115]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Bortezomib DMNO38U Leukemia Approved [297]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [362]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By T-box transcription factor TBX15 (TBX15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [142]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [473]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
GALLICACID DM6Y3A0 Discovery agent N.A. Investigative [451]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM83C (FAM83C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [441]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Leucine-rich repeat-containing protein 1 (LRRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [447]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [120]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FUN14 domain-containing protein 2 (FUNDC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [494]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [495]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Receptor for retinol uptake STRA6 (STRA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [496]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [497]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Complement C1q tumor necrosis factor-related protein 1 (C1QTNF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [362]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Periaxin (PRX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Selenium DM25CGV N. A. N. A. Approved [62]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Iroquois-class homeodomain protein IRX-2 (IRX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [379]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [474]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate receptor-interacting protein 2 (GRIP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Platelet-derived growth factor D (PDGFD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [498]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Very long chain fatty acid elongase 4 (ELOVL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [491]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [499]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Radial spoke head protein 6 homolog A (RSPH6A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Maleic Acid DM4L0R7 Discovery agent N.A. Investigative [500]
Drug(s) Affected By Pseudouridylate synthase PUS7L (PUS7L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [501]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [458]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ubiquitin-like-conjugating enzyme ATG10 (ATG10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [378]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
AT7519 DMCE08M Solid tumour/cancer 2A00-2F9Z Phase 1 [502]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [358]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Cytosolic beta-glucosidase (GBA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [294]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [294]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [89]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [131]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thiamin pyrophosphokinase 1 (TPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [192]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [501]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [411]
Topotecan DMP6G8T Central nervous system neoplasm Approved [120]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [501]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein ABHD16B (ABHD16B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [295]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [295]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Gremlin-2 (GREM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [351]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [121]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By L-2-hydroxyglutarate dehydrogenase, mitochondrial (L2HGDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [494]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [446]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [446]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protocadherin-9 (PCDH9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [352]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent transporter XTRP3 (SLC6A20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [503]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [227]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [504]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [501]
Chlorothiazide DMLHESP Chronic heart failure BD1Z Approved [505]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [136]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrix-remodeling-associated protein 5 (MXRA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Methotrexate DM2TEOL Anterior urethra cancer Approved [265]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [247]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [177]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [441]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disrupted in schizophrenia 1 protein (DISC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [5]
Clozapine DMFC71L Schizophrenia 6A20 Approved [506]
Dextroamphetamine DMMIHVP Attention deficit hyperactivity disorder 6A05.Z Approved [507]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C14orf119 (C14ORF119)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [405]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [192]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
RESORCINOL DMM37C0 Discovery agent N.A. Investigative [403]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Rhomboid-related protein 2 (RHBDL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [166]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [441]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [508]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [120]
Urethane DM7NSI0 N. A. N. A. Phase 4 [170]
OTX-015 DMI8RG1 Acute myeloid leukaemia 2A60 Phase 1/2 [453]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Taste receptor type 2 member 4 (TAS2R4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [412]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [161]
Milchsaure DM462BT Pruritus EC90 Investigative [137]
Drug(s) Affected By Semaphorin-5B (SEMA5B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [125]
Arsenic DMTL2Y1 N. A. N. A. Approved [509]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [411]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Methyl-CpG-binding domain protein 2 (MBD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [231]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [510]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Folic Acid DMEMBJC Colorectal carcinoma Approved [511]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [512]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [513]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [514]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By LIM/homeobox protein Lhx3 (LHX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [320]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [266]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [297]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [243]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Ephrin type-A receptor 6 (EPHA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [159]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [128]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Adherens junction-associated protein 1 (AJAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [515]
Methamphetamine DMPM4SK Anxiety Approved [516]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [142]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [142]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID27336223-Compound-5 DM6E50A N. A. N. A. Patented [515]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box/LRR-repeat protein 2 (FBXL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [179]
Capsaicin DMGMF6V Back pain ME84.Z Approved [517]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Disintegrin and metalloproteinase domain-containing protein 30 (ADAM30)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Peroxisomal carnitine O-octanoyltransferase (CROT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [518]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [518]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [255]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [371]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gap junction delta-2 protein (GJD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [383]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [519]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Glutamate receptor ionotropic, delta-1 (GRID1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [192]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [227]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Ras-related protein Rab-26 (RAB26)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [247]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [197]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [197]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [197]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [180]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein RP/EB family member 3 (MAPRE3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [381]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Folic Acid DMEMBJC Colorectal carcinoma Approved [148]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [294]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Paclitaxel DMLB81S Breast carcinoma Approved [520]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [184]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Afadin- and alpha-actinin-binding protein (SSX2IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [297]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [521]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [522]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ankyrin repeat domain-containing protein 6 (ANKRD6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [409]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [121]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [122]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [132]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [179]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By RNA-binding motif protein, X-linked 2 (RBMX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [458]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [462]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Sorting and assembly machinery component 50 homolog (SAMM50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [491]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [83]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [64]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [126]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin-like protein 7B (ACTL7B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [90]
Chlorothiazide DMLHESP Chronic heart failure BD1Z Approved [523]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [524]
Drug(s) Affected By Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (HS3ST3B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [297]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [525]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [181]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [118]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [164]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Roundabout homolog 1 (ROBO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [526]
Testosterone DM7HUNW Hot flushes GA30 Approved [133]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [527]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [528]
Arsenic DMTL2Y1 N. A. N. A. Approved [127]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Krueppel-like factor 10 (KLF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [529]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [285]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [146]
Leflunomide DMR8ONJ Arthritis FA20 Approved [150]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [294]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [286]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [298]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Liver carboxylesterase 1 (CES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [530]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [405]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [531]
Selenium DM25CGV N. A. N. A. Approved [62]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [532]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [533]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [534]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [535]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cocaine esterase (CES2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [534]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [536]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [531]
Methotrexate DM2TEOL Anterior urethra cancer Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [140]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [537]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [538]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [89]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [539]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [37]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [540]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [39]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [45]
Capsaicin DMGMF6V Back pain ME84.Z Approved [93]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [40]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [95]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [40]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [540]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [61]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium-binding protein 5 (CABP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [129]
Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [63]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [358]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [66]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [117]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Arsenic DMTL2Y1 N. A. N. A. Approved [541]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [135]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [359]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Sodium channel unspecific (NaC) TTRK8B9 NOUNIPROTAC Blocker [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [4]
Cytochrome P450 2B6 (CYP2B6) DEPKLMQ CP2B6_HUMAN Substrate [4]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase eta-1 (PLCH1) OT6Z1L2E PLCH1_HUMAN Gene/Protein Processing [5]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 (PFKFB1) OTTHX4NB F261_HUMAN Gene/Protein Processing [5]
Actin-like protein 7B (ACTL7B) OTCG3IGE ACL7B_HUMAN Gene/Protein Processing [5]
Acyl-CoA-binding domain-containing protein 5 (ACBD5) OT7L16DY ACBD5_HUMAN Gene/Protein Processing [5]
Adenylate kinase isoenzyme 1 (AK1) OT614AR3 KAD1_HUMAN Gene/Protein Processing [6]
Adherens junction-associated protein 1 (AJAP1) OTAAW121 AJAP1_HUMAN Gene/Protein Processing [5]
Afadin- and alpha-actinin-binding protein (SSX2IP) OTEIZ7N1 ADIP_HUMAN Gene/Protein Processing [5]
Aldehyde oxidase (AOX1) OT2FZP6H AOXA_HUMAN Gene/Protein Processing [5]
ALK and LTK ligand 2 (ALKAL2) OTTLHL64 ALKL2_HUMAN Gene/Protein Processing [5]
Alpha-2-macroglobulin-like protein 1 (A2ML1) OTWNUXIS A2ML1_HUMAN Gene/Protein Processing [5]

References

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