Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMSC4A7)

Drug Name
Indomethacin Drug Info
Synonyms
Aconip; Amuno; Arthrexin; Artracin; Artrinovo; Artrivia; Bonidin; Bonidon; Catlep; Confortid; Dolcidium; Dolovin; Durametacin; Elmetacin; Hicin; IMN; Idomethine; Imbrilon; Inacid; Indacin; Indameth; Indmethacine; Indocid; Indocin; Indomecol; Indomed; Indomee; Indometacin; Indometacina; Indometacine; Indometacinum; Indometacyna; Indomethacine; Indomethacinum; Indomethancin; Indomethazine; Indomethegan; Indomethine; Indometicina; Indomo; Indomod; Indoptic; Indoptol; Indorektal; Indoxen; Inflazon; Infrocin; Lausit; Liometacen; Metacen; Metartril; Methazine; Metindol; Mezolin; Miametan; Mikametan; Mobilan; Novomethacin; Reumacide; Sadoreum; Tannex; Vonum; Bonidon Gel; DESMETHYL INDOMETHACIN; Dolcidium PL;Flexin continus; Indocid Pda; Indocid Sr; Indocin Sr; Indolar SR; Indometacyna [Polish]; Indometicina [Spanish]; Inteban sp; Rhemacin LA; Rheumacin LA; I 7378; IN1454; Indomet 140; Aconip (TN); Apo-Indomethacin; Chibro-amuno; Chrono-indicid; Chrono-indocid; Indo-Lemmon; Indo-Spray; Indo-phlogont; Indo-rectolmin; Indo-tablinen; Indocid (TN); Indocid (pharmaceutical); Indocin (TN); Indocin I.V; Indometacina [INN-Spanish]; Indometacine [INN-French]; Indometacinum [INN-Latin]; Indomethacin (USP); Indomethacin [USAN:BAN]; Novo-Methacin; Indochron E-R (TN); Indocin I.V.; Indocin-SR (TN); Indometacin (JP15/INN); Indomethacin & MAP-30; Indomethacin, Indochron E-R, Indocin-SR, Indocid, Indocin, Indomethacin
Indication
Disease Entry ICD 11 Status REF
Bursitis Approved [1]
Gout FA25 Approved [1]
Osteoarthritis FA00-FA05 Approved [1]
Patent ductus arteriosus Approved [1]
Rheumatic disorder Approved [1]
Rheumatoid arthritis FA20 Approved [2]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 1/2 [3]
Synovitis Investigative [1]
Therapeutic Class
Antiinflammatory Agents
Cross-matching ID
PubChem CID
3715
ChEBI ID
CHEMBL6
CAS Number
CAS 53-86-1
TTD Drug ID
DMSC4A7
VARIDT Drug ID
DR00267
INTEDE Drug ID
DR0875
ACDINA Drug ID
D00329

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Prostaglandin G/H synthase 2 (COX-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [15]
Naproxen DMZ5RGV Bursitis Approved [16]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [17]
Celecoxib DM6LOQU Dysmenorrhea GA34.3 Approved [18]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [19]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [20]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [21]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [22]
Aminosalicylic Acid DMENSL5 Crohn disease DD70 Approved [4]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [23]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [24]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [25]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Folic Acid DMEMBJC Colorectal carcinoma Approved [27]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [26]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [26]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [28]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [26]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [29]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [30]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 1A1 (UGT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [31]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [32]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [33]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [34]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [35]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [36]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [37]
Metronidazole DMTIVEN Abscess Approved [38]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [39]
Ethanol DMDRQZU Chronic pain MG30 Approved [40]
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Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [42]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [43]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [44]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [45]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [44]
Verapamil DMA7PEW Angina pectoris BA40 Approved [46]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [47]
Estrone DM5T6US Acne vulgaris ED80 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [50]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [52]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [44]
Verapamil DMA7PEW Angina pectoris BA40 Approved [53]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [54]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [49]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [55]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [56]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 2B7 (UGT2B7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [57]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [58]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [6]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [60]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [61]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [62]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [63]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [64]
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Drug(s) Metabolized By UDP-glucuronosyltransferase 1A9 (UGT1A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [65]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [66]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [6]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [68]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [6]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [6]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [69]
Nateglinide DMLK2QH Diabetic complication 5A2Y Approved [6]
Haloperidol DM96SE0 Delirium Approved [6]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Gefitinib DM15F0X Colon adenocarcinoma Approved [71]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [74]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [76]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [77]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 1A (TNFRSF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [81]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [87]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [88]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [89]
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Drug(s) Affected By Solute carrier family 22 member 2 (SLC22A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [90]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [91]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [91]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [92]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [93]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [92]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [94]
Trospium chloride DM32XZT Discovery agent N.A. Approved [95]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [96]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
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Drug(s) Affected By Solute carrier family 22 member 1 (SLC22A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [96]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [90]
Trospium chloride DM32XZT Discovery agent N.A. Approved [95]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [98]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [93]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [101]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [94]
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Drug(s) Affected By Solute carrier family 22 member 6 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [102]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [103]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [94]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [94]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [104]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [94]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [105]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [94]
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Drug(s) Affected By Organic anion transporter 7 (SLC22A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [94]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [107]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [108]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [94]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [99]
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Drug(s) Affected By Solute carrier family 22 member 11 (SLC22A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [94]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [111]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [94]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [112]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [94]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [113]
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Drug(s) Affected By Solute carrier family 22 member 7 (SLC22A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [107]
Paclitaxel DMLB81S Breast carcinoma Approved [114]
Allopurinol DMLPAOB Gout FA25 Approved [114]
Bumetanide DMRV7H0 Congestive heart failure BD10 Approved [114]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [114]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [114]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [114]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [92]
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Drug(s) Affected By Aldo-keto reductase family 1 member C4 (AKR1C4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [115]
Diazepam DM08E9O Alcohol withdrawal Approved [116]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Benzbromarone DMC3YUA Gout FA25 Approved [117]
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Nitrazepam DMEGIQ6 Epilepsy 8A60-8A68 Approved [116]
Flunitrazepam DMGR5Z3 Insomnia 7A00-7A0Z Approved [116]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [118]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [119]
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Drug(s) Affected By Aldo-keto reductase family 1 member C2 (AKR1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [120]
Diazepam DM08E9O Alcohol withdrawal Approved [116]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [122]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [120]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [123]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [120]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
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Drug(s) Affected By Aldo-keto reductase family 1 member C1 (AKR1C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [126]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [120]
Diazepam DM08E9O Alcohol withdrawal Approved [116]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [127]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [120]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [128]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [129]
Ethacrynic acid DM60QMR Edema MG29 Approved [127]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [120]
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Drug(s) Affected By Diamine acetyltransferase 1 (SAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Selenium DM25CGV N. A. N. A. Approved [131]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [132]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [136]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [136]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
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Drug(s) Affected By Importin-5 (IPO5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [139]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
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Drug(s) Affected By Transcription factor E2F3 (E2F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [144]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [85]
Menthol DMG2KW7 Back pain ME84.Z Approved [147]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
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Drug(s) Affected By AT-rich interactive domain-containing protein 1A (ARID1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [152]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [153]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [154]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [149]
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Drug(s) Affected By Class E basic helix-loop-helix protein 40 (BHLHE40)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [155]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [156]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
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Drug(s) Affected By Chromodomain-helicase-DNA-binding protein 1 (CHD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [161]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [131]
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Drug(s) Affected By E3 ubiquitin-protein ligase Praja-2 (PJA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [164]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [166]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
Milchsaure DM462BT Pruritus EC90 Investigative [167]
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Drug(s) Affected By Phospholipid-transporting ATPase IC (ATP8B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [169]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [171]
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Drug(s) Affected By Zinc finger protein SNAI2 (SNAI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [172]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [173]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
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Drug(s) Affected By NUAK family SNF1-like kinase 1 (NUAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [177]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [177]
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Drug(s) Affected By cAMP-responsive element-binding protein-like 2 (CREBL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [178]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [140]
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Drug(s) Affected By Thiamine transporter 1 (SLC19A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [107]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [181]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [182]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily A member 2 (DNAJA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [184]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [185]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [184]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [186]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [187]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [171]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Frizzled-7 (FZD7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [189]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [184]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Suppressor of cytokine signaling 5 (SOCS5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Bortezomib DMNO38U Leukemia Approved [191]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [182]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
AMEP DMFELMQ Melanoma 2C30 Phase 1 [192]
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Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [197]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutaminase kidney isoform, mitochondrial (GLS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [199]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [200]
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Drug(s) Affected By Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Bortezomib DMNO38U Leukemia Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen activator inhibitor 1 (SERPINE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [203]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [205]
Methotrexate DM2TEOL Anterior urethra cancer Approved [206]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [207]
Quercetin DM3NC4M Obesity 5B81 Approved [208]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [210]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [213]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [214]
Fructose DM43AN2 Vomiting MD90 Approved [215]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [216]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [217]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [218]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [219]
Methotrexate DM2TEOL Anterior urethra cancer Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Lyn (LYN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [224]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [225]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [226]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [227]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [217]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [228]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [229]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [230]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [231]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein RO60 (RO60)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Selenium DM25CGV N. A. N. A. Approved [131]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [177]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor JunB (JUNB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [217]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [233]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [234]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein SON (SON)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [236]
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [177]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By COUP transcription factor 2 (NR2F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [237]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanylate-binding protein 1 (GBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [239]
Selenium DM25CGV N. A. N. A. Approved [131]
Methotrexate DM2TEOL Anterior urethra cancer Approved [240]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [240]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor SOX-18 (SOX18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [158]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [242]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [242]
Arsenic DMTL2Y1 N. A. N. A. Approved [243]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [109]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 receptor subunit beta (IL6ST)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [246]
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [247]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [89]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [89]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [70]
Gefitinib DM15F0X Colon adenocarcinoma Approved [248]
Prednisone DM2HG4X Acute asthma CA23 Approved [249]
Methotrexate DM2TEOL Anterior urethra cancer Approved [250]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [251]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [252]
Quercetin DM3NC4M Obesity 5B81 Approved [253]
Fluoxetine DM3PD2C Bipolar depression Approved [254]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [255]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 1A, X-chromosomal (EIF1AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [257]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [184]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein Tob1 (TOB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [259]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [191]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [261]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By UV excision repair protein RAD23 homolog B (RAD23B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Menthol DMG2KW7 Back pain ME84.Z Approved [147]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [161]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [262]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [263]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit e, mitochondrial (ATP5ME)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Selenium DM25CGV N. A. N. A. Approved [131]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [169]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [264]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [265]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ADP-ribosylation factor-like protein 4C (ARL4C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [268]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Folic Acid DMEMBJC Colorectal carcinoma Approved [269]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Bortezomib DMNO38U Leukemia Approved [191]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [270]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein BTG1 (BTG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [271]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [222]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [272]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [273]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [222]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho-related GTP-binding protein RhoB (RHOB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [274]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [274]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [275]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [257]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [276]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [277]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dystonin (DST)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [278]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [279]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Folic Acid DMEMBJC Colorectal carcinoma Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein phosphatase non-receptor type 12 (PTPN12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine-rich splicing factor 6 (SRSF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [281]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Ethanol DMDRQZU Chronic pain MG30 Approved [282]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [283]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [284]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [285]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [287]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [288]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [289]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PRP4 homolog (PRP4K)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [258]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [290]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G/T mismatch-specific thymine DNA glycosylase (TDG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [258]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [185]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [178]
Paclitaxel DMLB81S Breast carcinoma Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein EFR3 homolog A (EFR3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [291]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By AT-rich interactive domain-containing protein 5B (ARID5B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [292]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Folic Acid DMEMBJC Colorectal carcinoma Approved [280]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Arsenic DMTL2Y1 N. A. N. A. Approved [294]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By TSC22 domain family protein 1 (TSC22D1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [296]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [297]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Fluoxetine DM3PD2C Bipolar depression Approved [287]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Estrone DM5T6US Acne vulgaris ED80 Approved [297]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cleavage and polyadenylation specificity factor subunit 6 (CPSF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [184]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [258]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [184]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 6 (DUSP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [298]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [299]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [300]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein D53 (TPD52L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [177]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centrosome and spindle pole-associated protein 1 (CSPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Selenium DM25CGV N. A. N. A. Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [135]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [301]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [131]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein LBH (LBH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [99]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [283]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NHS-like protein 1 (NHSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Putative uncharacterized protein C6orf52 (C6ORF52)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [140]
Drug(s) Affected By PX domain-containing protein 1 (PXDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [304]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [135]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein AEBP2 (AEBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [305]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [306]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [149]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [307]
Hexadecanoic acid DMWUXDZ Discovery agent N.A. Investigative [308]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [309]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
Folic Acid DMEMBJC Colorectal carcinoma Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FMR1-interacting protein NUFIP2 (NUFIP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [310]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [311]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RNF144B (RNF144B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [312]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [182]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuroepithelial cell-transforming gene 1 protein (NET1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amphoterin-induced protein 2 (AMIGO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [240]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [240]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [314]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [240]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [270]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone-arginine methyltransferase METTL23 (METTL23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [310]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [315]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
Milchsaure DM462BT Pruritus EC90 Investigative [167]
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Drug(s) Affected By Protein O-mannosyl-transferase TMTC1 (TMTC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [181]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coiled-coil domain-containing protein 50 (CCDC50)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [273]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Arsenic DMTL2Y1 N. A. N. A. Approved [318]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase HACE1 (HACE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [319]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Ankyrin repeat domain-containing protein 13C (ANKRD13C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [320]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [321]
Milchsaure DM462BT Pruritus EC90 Investigative [167]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [322]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Hemicentin-2 (HMCN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Arsenic DMTL2Y1 N. A. N. A. Approved [323]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [244]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
APR-246 DMNFADH Ovarian cancer 2C73 Phase 2 [324]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [325]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Acrosin-binding protein (ACRBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [327]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
Piperazinyl methyl quinazolinone derivative 2 DM913KS N. A. N. A. Patented [328]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Mitochondria-eating protein (SPATA18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [199]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [135]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [242]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [242]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pantothenate kinase 1 (PANK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [177]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [99]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rap guanine nucleotide exchange factor 6 (RAPGEF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [131]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuronal cell adhesion molecule (NRCAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [329]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [181]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [330]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor GATA-6 (GATA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [239]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [239]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [331]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [239]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [239]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein TMEPAI (PMEPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [177]
Heroin diacetylmorphine DMDBWHY Neurological disorder 6B60 Approved [332]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arrestin domain-containing protein 3 (ARRDC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [259]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BTB/POZ domain-containing protein KCTD12 (KCTD12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [158]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Ethanol DMDRQZU Chronic pain MG30 Approved [333]
Benzatropine DMF7EXL Parkinsonian disorder Approved [334]
Clozapine DMFC71L Schizophrenia 6A20 Approved [334]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RING finger protein 145 (RNF145)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [171]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [335]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [336]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 237 (TMEM237)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Ethanol DMDRQZU Chronic pain MG30 Approved [282]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Trimethylguanosine synthase (TGS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [310]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [149]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [138]
Forskolin DM6ITNG Solid tumour/cancer 2A00-2F9Z Investigative [337]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [338]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By RNA-binding protein 15 (RBM15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Quercetin DM3NC4M Obesity 5B81 Approved [149]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [339]
Arsenic DMTL2Y1 N. A. N. A. Approved [340]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plakophilin-4 (PKP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [134]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cbp/p300-interacting transactivator 2 (CITED2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [233]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor SOX-7 (SOX7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [341]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [322]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [189]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [138]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [338]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [322]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Death-inducer obliterator 1 (DIDO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [322]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Activity-dependent neuroprotector homeobox protein (ADNP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [342]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [290]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interferon-stimulated 20 kDa exonuclease-like 2 (ISG20L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [271]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [271]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [271]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [271]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [271]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Adenine DMZLHKJ Malnutrition 5B50-5B71 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retroelement silencing factor 1 (RESF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [291]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [290]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DnaJ homolog subfamily C member 4 (DNAJC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Bortezomib DMNO38U Leukemia Approved [191]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [187]
Okadaic acid DM47CO1 Discovery agent N.A. Investigative [343]
L-serine DM6WPIS Pulmonary tuberculosis 1B10.Z Investigative [344]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Muscleblind-like protein 1 (MBNL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Bortezomib DMNO38U Leukemia Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [270]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [345]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sperm protein associated with the nucleus on the X chromosome A (SPANXA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [346]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [178]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [347]
Drug(s) Affected By Sal-like protein 1 (SALL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [303]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein phosphatase 4 regulatory subunit 2 (PPP4R2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [240]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [177]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [240]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [177]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PLK2 (PLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [348]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [181]
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Drug(s) Affected By ]-phosphatase 1, mitochondrial (PDP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [268]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [265]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [349]
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Drug(s) Affected By DNA repair protein REV1 (REV1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [350]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [351]
Urethane DM7NSI0 N. A. N. A. Phase 4 [165]
Guanine DMIWLJE N. A. N. A. Phase 3 [352]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [290]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [338]
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Drug(s) Affected By Translocation protein SEC63 homolog (SEC63)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Haloperidol DM96SE0 Delirium Approved [334]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Benzatropine DMF7EXL Parkinsonian disorder Approved [334]
Clozapine DMFC71L Schizophrenia 6A20 Approved [334]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [131]
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Drug(s) Affected By A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [353]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [278]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [329]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [268]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [181]
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Drug(s) Affected By Tomoregulin-2 (TMEFF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [354]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [291]
Folic Acid DMEMBJC Colorectal carcinoma Approved [355]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [356]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [291]
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Drug(s) Affected By F-box/WD repeat-containing protein 2 (FBXW2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
PHENOL DM1QSM3 N. A. N. A. Phase 2/3 [357]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [131]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
Nickel chloride DMI12Y8 Discovery agent N.A. Investigative [358]
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Drug(s) Affected By Scrapie-responsive protein 1 (SCRG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [135]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [319]
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Drug(s) Affected By Amino acid transporter heavy chain SLC3A2 (SLC3A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [259]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [107]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [287]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [287]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [177]
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Drug(s) Affected By Serine--tRNA ligase, cytoplasmic (SARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Haloperidol DM96SE0 Delirium Approved [334]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [177]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Benzatropine DMF7EXL Parkinsonian disorder Approved [334]
Clozapine DMFC71L Schizophrenia 6A20 Approved [334]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphoserine phosphatase (PSPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
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Drug(s) Affected By Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Methotrexate DM2TEOL Anterior urethra cancer Approved [360]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [361]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [362]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [363]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [222]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitochondrial 10-formyltetrahydrofolate dehydrogenase (ALDH1L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [299]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [364]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [314]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
Mitotane DMU1GX0 Adrenocortical carcinoma 2D11.Z Approved [365]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Lucanthone DMZLBUO Solid tumour/cancer 2A00-2F9Z Approved [366]
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Drug(s) Affected By Spermatogenesis-associated serine-rich protein 1 (SPATS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
Drug(s) Affected By Tribbles homolog 3 (TRIB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [287]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [367]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [287]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [299]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [368]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
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Drug(s) Affected By Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [287]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [369]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [370]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [359]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [364]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [369]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Racecadotril DMFOTZ7 Diarrhea ME05.1 Approved [371]
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Drug(s) Affected By Protein DEPP1 (DEPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [372]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [373]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [228]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [372]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [372]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Fluoxetine DM3PD2C Bipolar depression Approved [372]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [373]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [373]
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Drug(s) Affected By Cell cycle progression protein 1 (CCPG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [374]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ampicillin DMHWE7P Acute epiglottitis Approved [106]
Bortezomib DMNO38U Leukemia Approved [374]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
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Drug(s) Affected By Adenosine receptor A3 (ADORA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [375]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [376]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [377]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [378]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [379]
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Drug(s) Affected By 5'-nucleotidase (NT5E)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Quercetin DM3NC4M Obesity 5B81 Approved [380]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [278]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [99]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
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Drug(s) Affected By Aldo-keto reductase family 1 member C3 (AKR1C3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [120]
Diazepam DM08E9O Alcohol withdrawal Approved [116]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [381]
Desogestrel DM27U4Y Contraception QA21 Approved [381]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [120]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [120]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [382]
Quercetin DM3NC4M Obesity 5B81 Approved [383]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [384]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [385]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [385]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [386]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [384]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [385]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [387]
Gefitinib DM15F0X Colon adenocarcinoma Approved [384]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [388]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [384]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [389]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [390]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [391]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [392]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [393]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [394]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [395]
Gefitinib DM15F0X Colon adenocarcinoma Approved [396]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [397]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [398]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [399]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [390]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [400]
Paclitaxel DMLB81S Breast carcinoma Approved [401]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [402]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [389]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [215]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [392]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [393]
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Drug(s) Affected By Leukocyte cell-derived chemotaxin 1 (CNMD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [403]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [404]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [331]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [135]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [135]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [322]
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Drug(s) Affected By ABC-type organic anion transporter ABCA8 (ABCA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [108]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [99]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [109]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
Taurocholic Acid DM2LZ8F Type-2 diabetes 5A11 Phase 1/2 [405]
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Drug(s) Affected By RAS guanyl-releasing protein 1 (RASGRP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [321]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [378]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [406]
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Drug(s) Affected By C-X-C motif chemokine 14 (CXCL14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [189]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [407]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [408]
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Drug(s) Affected By Collagen alpha-1(II) chain (COL2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [353]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [296]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [189]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [409]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [410]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein Hox-D4 (HOXD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [378]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [291]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [149]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein Hox-D3 (HOXD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [411]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [378]
Arsenic DMTL2Y1 N. A. N. A. Approved [323]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [291]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [291]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [412]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
Rutin DMEHRAJ Discovery agent N.A. Investigative [413]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metalloproteinase inhibitor 3 (TIMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [414]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [415]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [416]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 4 group A member 2 (NR4A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [417]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [418]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [299]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [368]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [419]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [291]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [420]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By LIM/homeobox protein Lhx1 (LHX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
PHENCYCLIDINE DMQBEYX Discovery agent N.A. Investigative [421]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Ras association domain-containing protein 2 (RASSF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [314]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [422]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paired mesoderm homeobox protein 1 (PRRX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [312]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [423]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [12]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [424]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin light chain kinase, smooth muscle (MYLK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [275]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [425]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth/differentiation factor 6 (GDF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Arsenic DMTL2Y1 N. A. N. A. Approved [426]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [410]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
Nitrobenzanthrone DMN6L70 N. A. N. A. Investigative [427]
crotylaldehyde DMTWRQI Discovery agent N.A. Investigative [428]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Rhomboid-related protein 4 (RHBDD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [313]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [306]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [138]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SOSS complex subunit B2 (NABP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ribosomal protein eL39-like 2 (RPL39L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [429]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [97]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [188]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [171]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein Hox-D1 (HOXD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
Ethanol DMDRQZU Chronic pain MG30 Approved [282]
Ampicillin DMHWE7P Acute epiglottitis Approved [106]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [182]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Band 4.1-like protein 4B (EPB41L4B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [131]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [278]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [320]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [135]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Regulator of cell cycle RGCC (RGCC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [268]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ampicillin DMHWE7P Acute epiglottitis Approved [106]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [430]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [189]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein NANOG (NANOG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [431]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [432]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [433]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [434]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [435]
Testosterone DM7HUNW Hot flushes GA30 Approved [436]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [437]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Armadillo repeat-containing X-linked protein 1 (ARMCX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [283]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [142]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [290]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [303]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor erythroid 2-related factor 3 (NFE2L3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [287]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [287]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calpain-6 (CAPN6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [316]
Testosterone enanthate DMB6871 N. A. N. A. Approved [145]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Menthol DMG2KW7 Back pain ME84.Z Approved [147]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [378]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [438]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [439]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stearoyl-CoA desaturase (SCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [440]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [441]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [441]
Methotrexate DM2TEOL Anterior urethra cancer Approved [442]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [312]
Fluoxetine DM3PD2C Bipolar depression Approved [441]
Fructose DM43AN2 Vomiting MD90 Approved [443]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Bupropion DM5PCS7 Depression 6A70-6A7Z Approved [441]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [444]
Gefitinib DM15F0X Colon adenocarcinoma Approved [445]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [446]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Etretinate DM2CZFA Keratosis ED56 Approved [447]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [259]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [448]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [449]
Quercetin DM3NC4M Obesity 5B81 Approved [450]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [451]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 3 (ABCC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [452]
Methotrexate DM2TEOL Anterior urethra cancer Approved [453]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [454]
Calcipotriol DM03CP7 Psoriasis EA90 Approved [455]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [456]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [457]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Prednisone DM2HG4X Acute asthma CA23 Approved [458]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [459]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [460]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [461]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [462]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [463]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [13]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [464]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [465]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 21 (TNFRSF21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [183]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [466]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [170]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family C member 6 (ABCC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzbromarone DMC3YUA Gout FA25 Approved [467]
Verapamil DMA7PEW Angina pectoris BA40 Approved [467]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [468]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [107]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [108]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [469]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCN family member 4 (CCN4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [269]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [362]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [419]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Folic Acid DMEMBJC Colorectal carcinoma Approved [269]
Arsenic DMTL2Y1 N. A. N. A. Approved [470]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [471]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Renin (REN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [472]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [473]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [474]
Reboxetine DM26PRD Depression 6A70-6A7Z Approved [475]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [476]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [477]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [478]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [479]
Epinephrine DM3KJBC Acute asthma CA23 Approved [480]
Chlorthalidone DM4DMBT Edema MG29 Approved [481]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metalloproteinase inhibitor 1 (TIMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [215]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [482]
Verapamil DMA7PEW Angina pectoris BA40 Approved [483]
Selenium DM25CGV N. A. N. A. Approved [414]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [483]
Quercetin DM3NC4M Obesity 5B81 Approved [484]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [485]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [486]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [487]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [457]
Gefitinib DM15F0X Colon adenocarcinoma Approved [488]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [158]
Selenium DM25CGV N. A. N. A. Approved [489]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [490]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [74]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [491]
Methotrexate DM2TEOL Anterior urethra cancer Approved [442]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Natriuretic peptides A (NPPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [492]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [493]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [494]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [495]
Cilazapril DM4V6JA Congestive heart failure BD10 Approved [496]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [497]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [498]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [499]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [500]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Vasopressin-neurophysin 2-copeptin (AVP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [501]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [502]
Oxprenolol DM51OQW Anxiety Approved [503]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [504]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [505]
Luvox DMJKROX Anxiety disorder 6B00-6B0Z Approved [506]
Sodium chloride DMM3950 Skin burns ME65.0 Approved [507]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [502]
Chlorpropamide DMPHZQE Non-insulin dependent diabetes 5A11 Approved [508]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amyloid-beta precursor protein (APP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Selenium DM25CGV N. A. N. A. Approved [131]
Methotrexate DM2TEOL Anterior urethra cancer Approved [442]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [509]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [198]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [510]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [511]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [367]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [512]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein disulfide-isomerase (P4HB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [13]
Etretinate DM2CZFA Keratosis ED56 Approved [513]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [514]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [13]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [85]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [193]
Gefitinib DM15F0X Colon adenocarcinoma Approved [515]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [516]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [517]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [518]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [517]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [519]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [520]
Methotrexate DM2TEOL Anterior urethra cancer Approved [521]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Laminin subunit gamma-1 (LAMC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [522]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [523]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [130]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [258]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [524]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock cognate 71 kDa protein (HSPA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [525]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [236]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Etretinate DM2CZFA Keratosis ED56 Approved [513]
Quercetin DM3NC4M Obesity 5B81 Approved [526]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [281]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [527]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [528]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [529]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [239]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [172]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [530]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [531]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [532]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [533]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [534]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fatty acid-binding protein, adipocyte (FABP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [312]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [535]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [536]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [537]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [312]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [538]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [539]
Capsaicin DMGMF6V Back pain ME84.Z Approved [540]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 15-hydroxyprostaglandin dehydrogenase (HPGD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [442]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [312]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [541]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [9]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [9]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [542]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [13]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [464]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [543]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [211]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [13]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [544]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [545]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [546]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [547]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Gefitinib DM15F0X Colon adenocarcinoma Approved [548]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [549]
Methotrexate DM2TEOL Anterior urethra cancer Approved [550]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [551]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [552]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [236]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [368]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Febuxostat DMDEXQ0 Hyperuricaemia 5C55.Y Approved [553]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein kinase C eta type (PRKCH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [348]
Panobinostat DM58WKG Chronic graft versus host disease Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [143]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [135]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [302]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [320]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenomatous polyposis coli protein (APC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [279]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
Folic Acid DMEMBJC Colorectal carcinoma Approved [554]
Menthol DMG2KW7 Back pain ME84.Z Approved [147]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [159]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D2 (CCND2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Selenium DM25CGV N. A. N. A. Approved [489]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [555]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [556]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [557]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [558]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [216]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [559]
Quercetin DM3NC4M Obesity 5B81 Approved [560]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [561]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [562]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [563]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [564]
Testosterone DM7HUNW Hot flushes GA30 Approved [565]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [566]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Triacetin DM0AEPG Onychomycosis EE12.1 Approved [567]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [568]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [13]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [569]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [570]
Methotrexate DM2TEOL Anterior urethra cancer Approved [133]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [557]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [571]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [218]
Gefitinib DM15F0X Colon adenocarcinoma Approved [445]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Etretinate DM2CZFA Keratosis ED56 Approved [447]
Prednisone DM2HG4X Acute asthma CA23 Approved [249]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [518]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 4 (MAP2K4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [551]
Quercetin DM3NC4M Obesity 5B81 Approved [572]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Menthol DMG2KW7 Back pain ME84.Z Approved [147]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [573]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [574]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [551]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microsomal triglyceride transfer protein large subunit (MTTP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [13]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [575]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [13]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [13]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [575]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [576]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [577]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BH3-interacting domain death agonist (BID)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Selenium DM25CGV N. A. N. A. Approved [578]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [579]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [580]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [581]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [582]
Gefitinib DM15F0X Colon adenocarcinoma Approved [515]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [583]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [584]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [585]
Methotrexate DM2TEOL Anterior urethra cancer Approved [442]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [586]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [587]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [588]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [589]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [589]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [590]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [591]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [589]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [589]
Ethacrynic acid DM60QMR Edema MG29 Approved [589]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [589]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 4A11 (CYP4A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [592]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [593]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [593]
Methotrexate DM2TEOL Anterior urethra cancer Approved [442]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [274]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [274]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [593]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [593]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [593]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [594]
Selenium DM25CGV N. A. N. A. Approved [131]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [595]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [552]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [596]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [597]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [598]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tight junction protein ZO-1 (TJP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [599]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [97]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Ethanol DMDRQZU Chronic pain MG30 Approved [600]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [601]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [602]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [603]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Selenium DM25CGV N. A. N. A. Approved [131]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [604]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [605]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [606]
Quercetin DM3NC4M Obesity 5B81 Approved [83]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [607]
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Drug(s) Affected By Acetyl-CoA carboxylase 1 (ACACA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [608]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [560]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [609]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [537]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [610]
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Drug(s) Affected By Transcription factor HES-1 (HES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [611]
Selenium DM25CGV N. A. N. A. Approved [131]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [176]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
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Drug(s) Affected By Bcl-2 homologous antagonist/killer (BAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [612]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [613]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [614]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Levamisole DM5EN79 Parasitic infection 1D0Y-1G2Z Approved [615]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [616]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [617]
Promethazine DM6I5GR Hyperemesis gravidarum Approved [618]
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Drug(s) Affected By Occludin (OCLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [619]
Methotrexate DM2TEOL Anterior urethra cancer Approved [550]
Quercetin DM3NC4M Obesity 5B81 Approved [620]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [621]
Testosterone DM7HUNW Hot flushes GA30 Approved [125]
Thioguanine DM7NKEV Acute lymphocytic leukaemia 2B33.3 Approved [622]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ethanol DMDRQZU Chronic pain MG30 Approved [600]
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Drug(s) Affected By Dehydrogenase/reductase SDR family member 11 (DHRS11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [623]
Quercetin DM3NC4M Obesity 5B81 Approved [623]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [100]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Flufenamic Acid DMC8VNH Dysmenorrhea GA34.3 Approved [623]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [140]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
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Drug(s) Affected By Bcl2-associated agonist of cell death (BAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [624]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [285]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [245]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [625]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [626]
Quercetin DM3NC4M Obesity 5B81 Approved [627]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [628]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [212]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [87]
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Drug(s) Affected By Bcl-2-binding component 3, isoforms 3/4 (BBC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [286]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [259]
Methotrexate DM2TEOL Anterior urethra cancer Approved [360]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [629]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [128]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [363]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [630]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [631]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [632]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Perilipin-2 (PLIN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [633]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [536]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [177]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [634]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [264]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid-transporting ATPase ABCA3 (ABCA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [232]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [107]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [86]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [268]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [327]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [461]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [194]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [13]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [635]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [13]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [464]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [465]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [636]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome b5 (CYB5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [221]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [637]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [181]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock 70 kDa protein 12A (HSPA12A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [163]
Leflunomide DMR8ONJ Arthritis FA20 Approved [137]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [202]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [146]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [223]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [242]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [293]
Arsenic DMTL2Y1 N. A. N. A. Approved [326]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By p21 protein (HRAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [215]
Digoxin DMQCTIH Arrhythmia BC9Z Approved [215]
NVP-LAQ824 DM8JWNA Mood disorder 6A60-6E23 Phase 3 [215]
Drug(s) Affected By Transcriptional activator Myb (MYB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [297]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [78]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [555]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [222]
Estrone DM5T6US Acne vulgaris ED80 Approved [297]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [638]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [639]
Testosterone DM7HUNW Hot flushes GA30 Approved [175]
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Drug(s) Affected By NADH-cytochrome b5 reductase 3 (CYB5R3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [334]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [109]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [110]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [141]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [148]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Prostaglandin G/H synthase 2 (COX-2) TTVKILB PGH2_HUMAN Modulator [4]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [5]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Substrate [6]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [6]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [6]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DEB3CV1 UD2B7_HUMAN Substrate [7]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DE85D2P UD19_HUMAN Substrate [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
14-3-3 protein epsilon OT3WQXNA 1433E_HUMAN Gene/Protein Processing [8]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Gene/Protein Processing [9]
5'-nucleotidase (NT5E) OT7J5LT6 5NTD_HUMAN Gene/Protein Processing [10]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Gene/Protein Processing [11]
ABC-type organic anion transporter ABCA8 (ABCA8) OTCWLX6N ABCA8_HUMAN Gene/Protein Processing [12]
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Gene/Protein Processing [13]
Acrosin-binding protein (ACRBP) OT0MK3L1 ACRBP_HUMAN Gene/Protein Processing [11]
Activity-dependent neuroprotector homeobox protein (ADNP) OTEGICWR ADNP_HUMAN Gene/Protein Processing [11]
Adenomatous polyposis coli protein (APC) OTKV0TIK APC_HUMAN Gene/Protein Processing [14]
Adenosine receptor A3 (ADORA3) OTHO1BLK AA3R_HUMAN Gene/Protein Processing [10]

References

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65 Polymorphic expression of UGT1A9 is associated with variable acetaminophen glucuronidation in neonates: a population pharmacokinetic and pharmacogenetic study. Clin Pharmacokinet. 2018 Oct;57(10):1325-1336.
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67 Pharmacokinetic interaction involving sorafenib and the calcium-channel blocker felodipine in a patient with hepatocellular carcinoma. Invest New Drugs. 2011 Dec;29(6):1511-4.
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