Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMRZAQW)

Drug Name
PAF Drug Info
Synonyms
Platelet activating factor; PAF (C16); Platelet-activating factor; 74389-68-7; C16-PAF; 1-O-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; Hag-PC; APRL; Hexadecyl-paf-acether; Platelet-activating factor C16; 1-O-Hexadecyl-platelet-activating factor; PAF C-16; 1-O-Hexadecyl-2-O-acetyl-sn-glyceryl-3-phosphorylcholine; 1-O-Hexadecyl-2-acetyl-sn-glyceryl-3-phosphorylcholine; 1-Hexadecyl-2-acetyl-glycero-3-phosphocholine; C16-PAF acether; 1-Hexadecyl-2-acetyl-sn-glycero-3-phosphocholine; Blood platelet-activating factor; platelet activating factor; [3H]PAF
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
108156
ChEBI ID
CHEBI:44811
CAS Number
CAS 74389-68-7
TTD Drug ID
DMRZAQW

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Platelet-activating factor receptor (PTAFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ticlopidine DMO946V Acute coronary syndrome BA41 Approved [6]
RUPATADINE DMBPN7T N. A. N. A. Phase 4 [7]
ISRAPAFANT DMP61YB Asthma CA23 Phase 3 [8]
CMI-392 DM1NCUY Psoriasis vulgaris EA90 Phase 2 [9]
Lexipafant DMZ2YBE Nerve injury ND56.4 Phase 2 [10]
YM-264 DMAZNVX Sepsis 1G40-1G41 Phase 2 [11]
Dersalazine DMH96JW Inflammatory bowel disease DD72 Phase 2 [12]
60P002 DMHBN8X Dengue 1D20-1D2Z Phase 2 [13]
PegCNTF DMW7VGZ Obesity 5B81 Phase 1 [14]
FOROPAFANT DML1DGP Asthma CA23 Discontinued in Phase 3 [15]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [16]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [17]
Fructose DM43AN2 Vomiting MD90 Approved [18]
Ketoprofen DMRKXPT Bursitis Approved [18]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [19]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [20]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [21]
Gefitinib DM15F0X Colon adenocarcinoma Approved [22]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [23]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
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Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [26]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [26]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Quercetin DM3NC4M Obesity 5B81 Approved [28]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [26]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [29]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [30]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Gefitinib DM15F0X Colon adenocarcinoma Approved [33]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [26]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [35]
Selenium DM25CGV N. A. N. A. Approved [36]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [37]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [38]
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Drug(s) Affected By C-reactive protein (CRP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [18]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [39]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [42]
Acalabrutinib DM7GCVW leukaemia 2A60-2B33 Approved [43]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [44]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [45]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [46]
Testosterone DM7HUNW Hot flushes GA30 Approved [47]
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Drug(s) Affected By Polyunsaturated fatty acid 5-lipoxygenase (ALOX5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [48]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [49]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [50]
Fructose DM43AN2 Vomiting MD90 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [55]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [56]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [57]
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Drug(s) Affected By E-selectin (SELE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [58]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Methotrexate DM2TEOL Anterior urethra cancer Approved [60]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [61]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [63]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [64]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [46]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [65]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [66]
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Drug(s) Affected By Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Quercetin DM3NC4M Obesity 5B81 Approved [67]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [68]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [69]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [67]
Bortezomib DMNO38U Leukemia Approved [70]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [67]
BAICALEIN DM4C7E6 Influenza virus infection 1E30-1E32 Phase 2 [67]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [71]
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Drug(s) Affected By Early growth response protein 1 (EGR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [72]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [73]
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Quercetin DM3NC4M Obesity 5B81 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [29]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [78]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [79]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [80]
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Drug(s) Affected By Prostaglandin G/H synthase 1 (PTGS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [81]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [83]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [29]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [85]
Bupivacaine DM4PRFC Anaesthesia 9A78.6 Approved [86]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [85]
Panobinostat DM58WKG Chronic graft versus host disease Approved [87]
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Drug(s) Affected By Type-1 angiotensin II receptor (AGTR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [89]
Quercetin DM3NC4M Obesity 5B81 Approved [90]
Fructose DM43AN2 Vomiting MD90 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Estriol DMOEM2I Hormone deficiency 5A61.1 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [95]
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Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [96]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [97]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [98]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [99]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [83]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [100]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [101]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [102]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [103]
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Drug(s) Affected By C-C chemokine receptor type 2 (CCR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [74]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [107]
Ethanol DMDRQZU Chronic pain MG30 Approved [108]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [109]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [110]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [111]
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Drug(s) Affected By Collagenase 3 (MMP13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [112]
Clindamycin DM15HL8 Acne vulgaris ED80 Approved [113]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [112]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [114]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [115]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [116]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [92]
Doxycycline DM7ICNU Acne vulgaris ED80 Approved [113]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [117]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [118]
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Drug(s) Affected By CX3C chemokine receptor 1 (CX3CR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [30]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [121]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [122]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [123]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [124]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [125]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [126]
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Drug(s) Affected By Oxidized low-density lipoprotein receptor 1 (OLR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [127]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [127]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [128]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [129]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [130]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [131]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [127]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [127]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [132]
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Drug(s) Affected By Peroxisome proliferator-activated receptor alpha (PPARA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [136]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [137]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [138]
Testosterone DM7HUNW Hot flushes GA30 Approved [139]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [140]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
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Drug(s) Affected By Metalloproteinase inhibitor 4 (TIMP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [141]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Isoproterenol DMK7MEY Atrioventricular block Approved [142]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [143]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [144]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [145]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [146]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [147]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [148]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [149]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [150]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [151]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [152]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [153]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [35]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [154]
Methotrexate DM2TEOL Anterior urethra cancer Approved [150]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [155]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [156]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [157]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [152]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [158]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [32]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [34]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [159]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [26]
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Drug(s) Affected By Integrin alpha-M (ITGAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [160]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [161]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [163]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [107]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [164]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [165]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [166]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [167]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [168]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [153]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [102]
Gefitinib DM15F0X Colon adenocarcinoma Approved [169]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [24]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [170]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [171]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [173]
Quercetin DM3NC4M Obesity 5B81 Approved [174]
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Drug(s) Affected By L-selectin (SELL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [175]
Meloxicam DM2AR7L Arthritis FA20 Approved [175]
Methotrexate DM2TEOL Anterior urethra cancer Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [161]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [64]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [175]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [176]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [175]
Phenylbutazone DMAYL0T Chronic pain MG30 Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
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Drug(s) Affected By P-selectin (SELP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [30]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [178]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [179]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [54]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [180]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [181]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [182]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [183]
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Drug(s) Affected By Platelet-activating factor acetylhydrolase (PLA2G7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [184]
Panobinostat DM58WKG Chronic graft versus host disease Approved [87]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [185]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [187]
Vitamin B3 DMQVRZH Chronic renal failure GB61.Z Approved [188]
Orlistat DMRJSP8 Obesity 5B81 Approved [187]
Nitrous oxide DMTHWBI Anxiety disorder 6B00-6B0Z Approved [189]
Arsenic DMTL2Y1 N. A. N. A. Approved [190]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [191]
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Drug(s) Affected By Myeloid differentiation primary response protein MyD88 (MYD88)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [192]
Quercetin DM3NC4M Obesity 5B81 Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [161]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [194]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [93]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [186]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [196]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [194]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Platelet-activating factor receptor (PTAFR) TTQL5VC PTAFR_HUMAN Agonist [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
C-C chemokine receptor type 2 (CCR2) OTQ7T10J CCR2_HUMAN Gene/Protein Processing [3]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Protein Interaction/Cellular Processes [4]
C-reactive protein (CRP) OT0RFT8F CRP_HUMAN Gene/Protein Processing [3]
Collagenase 3 (MMP13) OTY8BZIE MMP13_HUMAN Gene/Protein Processing [3]
CX3C chemokine receptor 1 (CX3CR1) OTIM9XT8 CX3C1_HUMAN Gene/Protein Processing [3]
E-selectin (SELE) OT33RZWY LYAM2_HUMAN Gene/Protein Processing [3]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Gene/Protein Processing [3]
Integrin alpha-M (ITGAM) OTAG6HWU ITAM_HUMAN Gene/Protein Processing [5]
Interleukin-1 alpha (IL1A) OTPSGILV IL1A_HUMAN Gene/Protein Processing [3]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Gene/Protein Processing [3]

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