Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM6T924)

Drug Name

Gabapentin Drug Info

Synonyms

Aclonium; GBN; Gabapen; Gabapentina; Gabapentine; Gabapentinium; Gabapentino; Gabapentinum; Gabapetin; Neurontin; Serada; Vultin; Apotex brand of gabapentin; Aventis brand of gabapentin; Gabapentin GR; Gabapentin Hexal; Gabapentin Stada; Gabapentino [Spanish]; Hexal brand of gabapentin; Novopharm brand of gabapentin; Parke Davis brand of gabapentin; Pfizer brand of gabapentin; Pharmascience brand of gabapentin; Ratiopharm brand of gabapentin; Stadapharm brand of gabapentin; GOE 2450; Go 3450; Apo-Gabapentin; DDS-2003; DM-1796; DM-5689; G-154; Gabapentin (Neurontin); Gabapentin-ratiopharm; Gabapentine [INN-French]; Gabapentino [INN-Spanish]; Gabapentinum [INN-Latin]; Goe-3450; Neurontin (TN); Novo-Gabapentin; PMS-Gabapentin; Warner-Lambert brand of gabapentin; Gabapentin [USAN:INN:BAN]; [1-(AMINOMETHYL)CYCLOHEXYL]ACETIC ACID; Gabapentin (JAN/USAN/INN); 1-(Aminomethyl)-cyclohexaneacetic acid; 1-(Aminomethyl)cyclohexaneacetic acid; 2-[1-(aminomethyl)cyclohexyl]acetic acid

Indication

Disease Entry	ICD 11	Status	REF
Complex partial seizure	8A68.0	Approved	[1]
Postherpetic neuralgia	1E91.5	Approved	[2]
Solid tumour/cancer	2A00-2F9Z	Phase 3	[1]

Therapeutic Class

Analgesics

Cross-matching ID

PubChem CID: 3446
ChEBI ID: CHEBI:42797
CAS Number: CAS 60142-96-3
TTD Drug ID: DM6T924
VARIDT Drug ID: DR00217
ACDINA Drug ID: D00296

Molecule-Related Drug Atlas

Molecule Type:

DTT

DTP

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

Investigative Drug(s)

Patented Agent(s)

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Drug(s) Targeting Gamma-aminobutyric acid B receptor (GABBR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gamma Hydroxybutyric Acid	DMGBKVD	Narcolepsy	7A20	Approved	[10]
Baclofen	DM0QV1J	Multiple sclerosis	8A40	Approved	[11]
Progabide	DM671NG	Depression	6A70-6A7Z	Approved	[12]
Arbaclofen placarbil	DMO628K	Fragile X syndrome	LD55	Phase 3	[13]
[3H](R)-(-)-baclofen	DMLRHM5	Multiple sclerosis	8A40	Phase 3	[14]
Arabaclofen	DMZB9RI	Fragile X syndrome	LD55	Phase 3	[15]
GSK683699	DMTW79H	Inflammatory bowel disease	DD72	Phase 2	[16]
SGS742	DM5XYFH	Schizophrenia	6A20	Phase 2	[17]
SSTarbaclofen	DMRGTZ2	Autism spectrum disorder	6A02	Phase 2	[18]
ASP8062	DMR1MIV	Fibromyalgia	MG30.01	Phase 2	[19]
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Drug(s) Transported By Organic cation transporter 2 (SLC22A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dinoprostone	DMTYOPD	Medical abortion	JA00.1Z	Approved	[20]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[21]
Oxaliplatin	DMQNWRD	Adenocarcinoma	2D40	Approved	[22]
Quinine	DMSWYF5	Malaria	1F40-1F45	Approved	[23]
Dopamine	DMPGUCF	Acromegaly	5A60.0	Approved	[24]
Propranolol	DM79NTF	Angina pectoris	BA40	Approved	[25]
Ergotidine	DM78IME	Osteoarthritis	FA00-FA05	Approved	[26]
Metformin	DM89QE1	Colorectal carcinoma		Approved	[27]
Clonidine	DM6RZ9Q	Attention deficit hyperactivity disorder	6A05.Z	Approved	[25]
Ranitidine	DM0GUSX	Gastric ulcer	DA60	Approved	[28]
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Drug(s) Transported By Organic cation/carnitine transporter 1 (SLC22A4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[29]
Quinine	DMSWYF5	Malaria	1F40-1F45	Approved	[29]
Cytarabine	DMZD5QR	Acute lymphoblastic leukaemia	2A85	Approved	[30]
Levacecarnine hci	DMJBOCR	Cognitive impairment	6D71	Approved	[31]
Ipratropium	DMFQ320	Obstructive lung disease	CA22.Z	Approved	[32]
[14C]TEA	DM6SFYH	Discovery agent	N.A.	Investigative	[33]
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Drug(s) Transported By L-type amino acid transporter 1 (SLC7A5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-glutamine	DM69G8X	Short bowel syndrome	KB89.1	Approved	[34]
Levodopa	DMN3E57	Parkinson disease	8A00.0	Approved	[35]
Pregabalin	DMDVP3B	Chronic obstructive pulmonary disease	CA22	Approved	[36]
L-leucine	DMQHN7I	Discovery agent	N.A.	Investigative	[34]
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Drug(s) Affected By D(1A) dopamine receptor (DRD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Haloperidol	DM96SE0	Delirium		Approved	[37]
Flupentixol	DM0DJ9O	Schizophrenia	6A20	Approved	[38]
Pergolide mesylate	DM5GKOV	N. A.	N. A.	Approved	[39]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[37]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[40]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Dopamine	DMPGUCF	Acromegaly	5A60.0	Approved	[42]
Methamphetamine	DMPM4SK	Anxiety		Approved	[43]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[44]
Bardoxolone methyl	DMODA2X	Mixed connective tissue disease	4A43.3	Phase 3	[45]
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Drug(s) Affected By Histamine H1 receptor (HRH1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Desloratadine	DM56YN7	Allergic rhinitis	CA08.0	Approved	[46]
Loratadine	DMF3AN7	Allergy	4A80-4A85	Approved	[46]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[47]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[48]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[49]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[50]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[51]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[52]
Olanzapine	DMPFN6Y	Bipolar depression		Approved	[51]
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Drug(s) Affected By 5-hydroxytryptamine receptor 3A (HTR3A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[53]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[54]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[55]
Metoclopramide	DMFA5MY	Nausea	MD90	Approved	[56]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[57]
Hydromorphone	DMHP21E	Back pain	ME84.Z	Approved	[58]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[59]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[54]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[53]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[60]
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Drug(s) Affected By Muscarinic acetylcholine receptor M1 (CHRM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Pirenzepine	DMP6M1N	Peptic ulcer	DA61	Approved	[61]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[62]
Acetylcholine	DMDF79Z	Cataract	9B10	Approved	[63]
Atropine	DMEN6X7	Organophosphate poisoning	NE6Z	Approved	[64]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[65]
Olanzapine	DMPFN6Y	Bipolar depression		Approved	[51]
Gallamine Triethiodide	DMPO0MS	Stabilize muscle contraction	FB3Z	Approved	[66]
Carbachol	DMX9K8F	Glaucoma/ocular hypertension	9C61	Approved	[63]
Methylscopolamine	DM5VWOB	Peptic ulcer	DA61	Approved	[67]
Dihydrotestosterone	DM3S8XC	Prostate hyperplasia	GA90	Phase 4	[68]
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Drug(s) Affected By 5-hydroxytryptamine receptor 2B (HTR2B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[62]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Mifepristone	DMGZQEF	Cushing disease	5A70	Approved	[69]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[70]
Bortezomib	DMNO38U	Leukemia		Approved	[71]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[72]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[73]
Fenfluramine	DM0762O	Dravet syndrome	8A61.11	Phase 3	[74]
GSK2110183	DMZHB37	leukaemia	2A60-2B33	Phase 2	[75]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[76]
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Drug(s) Affected By Alpha-1A adrenergic receptor (ADRA1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tamsulosin	DM5QF9V	Benign prostatic hyperplasia	GA90	Approved	[77]
SILODOSIN	DMJSBT6	Benign prostatic hyperplasia	GA90	Approved	[78]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[79]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[78]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[80]
Oxymetazoline	DM8ZXT6	Arrhythmia	BC9Z	Approved	[77]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[50]
Quinidine	DMLPICK	N. A.	N. A.	Approved	[79]
Norepinephrine	DMOUC09	Alopecia	ED70	Approved	[81]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[82]
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Drug(s) Affected By 5-hydroxytryptamine receptor 2A (HTR2A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fluphenazine	DMIT8LX	Psychotic disorder	6A20-6A25	Approved	[83]
Paliperidone	DM7NPJS	Psychotic disorder	6A20-6A25	Approved	[84]
Haloperidol	DM96SE0	Delirium		Approved	[84]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Olanzapine	DMPFN6Y	Bipolar depression		Approved	[51]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[86]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[87]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[88]
Ketanserin	DMVLMW6	Hypertension	BA00-BA04	Approved	[89]
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Drug(s) Affected By Glutamine--fructose-6-phosphate aminotransferase 1 (GFPT1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
L-glutamine	DM69G8X	Short bowel syndrome	KB89.1	Approved	[7]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[90]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[91]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[92]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[93]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[94]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[50]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[95]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[96]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[97]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[98]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[99]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[100]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[101]
Imiquimod	DM1TMA3	Alopecia areata	ED70.2	Approved	[102]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[103]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[104]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[105]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[48]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[106]
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Drug(s) Affected By Serum paraoxonase/arylesterase 1 (PON1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Primidone	DM0WX6I	Epilepsy	8A60-8A68	Approved	[107]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[108]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[109]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[110]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[111]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[112]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[113]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[114]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[115]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[50]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Flupentixol	DM0DJ9O	Schizophrenia	6A20	Approved	[116]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[117]
Crizotinib	DM4F29C	Non-small-cell lung cancer	2C25.Y	Approved	[118]
Lamotrigine	DM8SXYG	Bipolar disorder	6A60	Approved	[8]
Cepharanthine	DM9Y5JB	N. A.	N. A.	Approved	[119]
Itraconazole	DMCR1MV	Aspergillosis	1F20	Approved	[120]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[121]
Midostaurin	DMI6E0R	Acute myeloid leukaemia	2A60	Approved	[122]
Trifluoperazine	DMKBYWI	Anxiety		Approved	[123]
Olanzapine	DMPFN6Y	Bipolar depression		Approved	[121]
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Drug(s) Affected By Lactoperoxidase (LPO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[9]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[9]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[9]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[124]
Sulfadiazine	DMTW3R8	Rheumatic fever	1B40-1B42	Approved	[9]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[9]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[76]
Glyphosate	DM0AFY7	Malaria	1F40-1F45	Investigative	[9]
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Drug(s) Affected By Sodium-dependent serotonin transporter (SLC6A4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Paroxetine	DM5PVQE	Anxiety disorder	6B00-6B0Z	Approved	[125]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[126]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[127]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[128]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[9]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[129]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[130]
Aripiprazole	DM3NUMH	Bipolar I disorder		Approved	[131]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[132]
Mepyramine	DMB4SFH	Allergic rhinitis	CA08.0	Approved	[133]
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Drug(s) Affected By Serine/threonine-protein kinase mTOR (MTOR)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[134]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[99]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[135]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[136]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[137]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[138]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[9]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[139]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[140]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[141]
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Drug(s) Affected By Glutamate receptor ionotropic, NMDA 1 (GRIN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[9]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[9]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[142]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[94]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[143]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[144]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[145]
Sulfadiazine	DMTW3R8	Rheumatic fever	1B40-1B42	Approved	[9]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[9]
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Drug(s) Affected By Potassium voltage-gated channel subfamily H member 2 (KCNH2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Metoclopramide	DMFA5MY	Nausea	MD90	Approved	[146]
Quinidine	DMLPICK	N. A.	N. A.	Approved	[147]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[148]
Erythromycin	DM4K7GQ	Acne vulgaris	ED80	Approved	[149]
Clarithromycin	DM4M1SG	Acute maxillary sinusitis		Approved	[149]
Disopyramide	DM5SYZP	Long QT syndrome	BC65.0	Approved	[150]
Propranolol	DM79NTF	Angina pectoris	BA40	Approved	[151]
Amiodarone	DMUTEX3	Tachyarrhythmias	BC71	Approved	[152]
Dofetilide	DMPN1TW	Sinus rhythm disorder	BC9Y	Approved	[153]
Flecainide	DMSQDLE	Tachyarrhythmias	BC71	Approved	[149]
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Drug(s) Affected By Voltage-dependent calcium channel subunit alpha-2/delta-2 (CACNA2D2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[154]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[143]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[155]
Mitoxantrone	DMM39BF	Acute myelogenous leukaemia	2A41	Approved	[156]
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[156]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[156]
Carbamazepine	DMZOLBI	Epilepsy	8A60-8A68	Approved	[157]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[76]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[90]
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Drug(s) Affected By SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[127]
Selenium	DM25CGV	N. A.	N. A.	Approved	[158]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[9]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[9]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[159]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[50]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[41]
Melphalan	DMOLNHF	Hematologic disease	3C0Z	Approved	[160]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[161]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[162]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Gamma-aminobutyric acid B receptor (GABBR)	TTDCVZW	GABR1_HUMAN; GABR2_HUMAN	Antagonist	[3]

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Drug Transporter (DTP)

DTP Name	DTP ID	UniProt ID	MOA	REF
L-type amino acid transporter 1 (SLC7A5)	DT48T0N	LAT1_HUMAN	Substrate	[4]
Organic cation/carnitine transporter 1 (SLC22A4)	DT2EG60	S22A4_HUMAN	Substrate	[5]
Organic cation transporter 2 (SLC22A2)	DT9IDPW	S22A2_HUMAN	Substrate	[6]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
5-hydroxytryptamine receptor 2A (HTR2A)	OTWXJX0M	5HT2A_HUMAN	Drug Response	[7]
5-hydroxytryptamine receptor 2B (HTR2B)	OTM1AD9J	5HT2B_HUMAN	Drug Response	[7]
5-hydroxytryptamine receptor 3A (HTR3A)	OTAIV1AK	5HT3A_HUMAN	Drug Response	[7]
Alpha-1A adrenergic receptor (ADRA1A)	OTUIWCL5	ADA1A_HUMAN	Drug Response	[7]
ATP-dependent translocase ABCB1 (ABCB1)	OTEJROBO	MDR1_HUMAN	Gene/Protein Processing	[8]
D(1A) dopamine receptor (DRD1)	OTLZPBT7	DRD1_HUMAN	Drug Response	[7]
Glutamate receptor ionotropic, NMDA 1 (GRIN1)	OTZ5YBO8	NMDZ1_HUMAN	Gene/Protein Processing	[9]
Glutamine--fructose-6-phosphate aminotransferase 1 (GFPT1)	OTQBDO45	GFPT1_HUMAN	Drug Response	[7]
Histamine H1 receptor (HRH1)	OT8F9FV6	HRH1_HUMAN	Drug Response	[7]
Lactoperoxidase (LPO)	OTJ9QKX9	PERL_HUMAN	Gene/Protein Processing	[9]

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