Details of the Drug-Related molecule(s) Interaction Atlas

Fenthion Drug Info

Baytex; ENT 25,540; Fenthion 4E; Fenthion [BAN]; Fenthion [BSI:ISO]; Fenthion-methyl; Fenthione; Figuron; Lebaycid; Lebayeid; MPP (pesticide); Mercaptophos; Mosquitocide 700; Phenthion; Pro-Spot; Queletox; S 1752; Spotton; Sulfidophos; Talodex; Tiguvon; fenthion; 4-Methylmercapto-3-methylphenyl dimethyl thiophosphate; 55-38-9; B 29493; BAY 29493; Bay-Bassa; Baycid; Bayer 29493; Bayer 9007; Bayer S-1752; BL0L45OVKT; C10H15O3PS2; CCRIS 310; Caswell No. 456F; EINECS 200-231-9; Entex; HSDB 1403; NCI-C08651; OMS 2; UNII-BL0L45OVKT

Cross-matching ID

PubChem CID

3346

ChEBI ID

CHEBI:34761

CAS Number

CAS 55-38-9

TTD Drug ID

DMKEG49

INTEDE Drug ID

DR1945

General Information of Drug (ID: DMKEG49)

Molecule-Related Drug Atlas

Molecule Type:

DME

DOT

Drug Status:

Approved Drug(s)

Clinical Trial Drug(s)

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Drug(s) Metabolized By Cytochrome P450 2A6 (CYP2A6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[7]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[8]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[9]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[10]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[8]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[11]
Metronidazole	DMTIVEN	Abscess		Approved	[12]
Propofol	DMB4OLE	Anaesthesia	9A78.6	Approved	[13]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[14]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[8]
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Drug(s) Affected By Acetylcholinesterase (ACHE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetylcholine	DMDF79Z	Cataract	9B10	Approved	[15]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[16]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[17]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[18]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[19]
L-Glutamic Acid	DM4PUDW	Schizophrenia	6A20	Approved	[17]
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[20]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[21]
Neostigmine	DM6T2J3	Myasthenia gravis	8C6Y	Approved	[22]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[23]
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Drug(s) Affected By Cholinesterase (BCHE)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[24]
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[25]
Galantamine	DMEO794	Alzheimer disease	8A20	Approved	[26]
Rivastigmine	DMG629M	Alzheimer disease	8A20	Approved	[27]
Donepezil	DMIYG7Z	Advanced cancer	2A00-2F9Z	Approved	[28]
Succinylcholine	DM2ET1M	Plasma cell myeloma	2A83.1	Approved	[29]
Ethopropazine	DM0N3L7	Parkinson disease	8A00.0	Approved	[25]
Dimenhydrinate	DM264B3	Meniere disease	AB31.0	Approved	[30]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[31]
Chlorpheniramine	DM5URA2	Allergic rhinitis	CA08.0	Approved	[30]
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Drug(s) Affected By Suppressor of cytokine signaling 3 (SOCS3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[32]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[33]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[18]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[34]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[35]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[36]
Fedratinib	DM4ZBK6	Myelofibrosis	2A20.2	Approved	[37]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[38]
Pyrimethamine	DM5X7VY	Malaria	1F40-1F45	Approved	[37]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[35]
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Drug(s) Affected By Protein phosphatase 1 regulatory subunit 15A (PPP1R15A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[39]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[40]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[41]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[42]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[44]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[45]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[46]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[47]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[48]
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Drug(s) Affected By Protein c-Fos (FOS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[49]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[50]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[51]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[40]
Acebutolol	DM0TI4U	Hypertension	BA00-BA04	Approved	[51]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[52]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[53]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[54]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[55]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[57]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[40]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[52]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[58]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[59]
Selenium	DM25CGV	N. A.	N. A.	Approved	[60]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[61]
Trametinib	DM2JGQ3	Melanoma	2C30	Approved	[62]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[63]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[64]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[65]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[64]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[66]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[67]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[68]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[69]
Floxuridine	DM04LR2	Colorectal cancer	2B91.Z	Approved	[70]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[71]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[72]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[73]
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Drug(s) Affected By Transcription factor Jun (JUN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Mitoxantrone	DMM39BF	Acute myelogenous leukaemia	2A41	Approved	[74]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[75]
Fructose	DM43AN2	Vomiting	MD90	Approved	[28]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[76]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[77]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[40]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[78]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[79]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[80]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[81]
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Drug(s) Affected By Histone H2AX (H2AX)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[82]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[83]
Selenium	DM25CGV	N. A.	N. A.	Approved	[84]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[85]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[86]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[87]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[88]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[89]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[90]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[91]
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Drug(s) Affected By Tumor necrosis factor alpha-induced protein 3 (TNFAIP3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[92]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[93]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[94]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[44]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[95]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[92]
Ethacrynic acid	DM60QMR	Edema	MG29	Approved	[96]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[97]
Trovafloxacin	DM6AN32	Acute gonococcal cervicitis		Approved	[98]
Clonidine	DM6RZ9Q	Attention deficit hyperactivity disorder	6A05.Z	Approved	[92]
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Drug(s) Affected By Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[99]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[100]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[101]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[49]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[47]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[102]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[102]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[103]
Febuxostat	DMDEXQ0	Hyperuricaemia	5C55.Y	Approved	[104]
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Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[39]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[40]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[105]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[106]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[107]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[108]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[109]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[110]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[111]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[112]
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Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[113]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[114]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[115]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[116]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[117]
Glucosamine	DM4ZLFD	Osteoarthritis	FA00-FA05	Approved	[118]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[119]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[120]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[121]
Stavudine	DM6DEK9	Human immunodeficiency virus infection	1C62	Approved	[122]
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Drug(s) Affected By Breast cancer type 1 susceptibility protein (BRCA1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[93]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[123]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[124]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[125]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[126]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[110]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[127]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[44]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[128]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[49]
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Drug(s) Affected By Type I iodothyronine deiodinase (DIO1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[129]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[43]
Rifampicin	DM5DSFZ	Non-insulin dependent diabetes	5A11	Approved	[130]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[131]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[132]
Ergocalciferol	DMHO0AR	Hypoparathyroidism	5A50	Approved	[133]
Alitretinoin	DMME8LH	Kaposi sarcoma	2B57	Approved	[134]
Masoprocol	DMMVNZ0	Prostate cancer	2C82.0	Approved	[133]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[135]
Amiodarone	DMUTEX3	Tachyarrhythmias	BC71	Approved	[136]
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Drug(s) Affected By Estrogen-related receptor gamma (ESRRG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[137]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[49]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[138]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[131]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[139]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[140]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[141]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[142]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[143]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[144]
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Drug(s) Affected By DNA repair protein RAD51 homolog 1 (RAD51)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[145]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[146]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[147]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[148]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[44]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[149]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[102]
Quizartinib	DM8Y4JS	Acute myeloid leukaemia	2A60	Approved	[150]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[102]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[103]
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Drug(s) Affected By E3 ubiquitin-protein ligase RAD18 (RAD18)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[95]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[102]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[102]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[151]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[152]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[153]
Vorinostat	DMWMPD4	Adult acute monocytic leukemia		Approved	[154]
GSK2110183	DMZHB37	leukaemia	2A60-2B33	Phase 2	[155]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[156]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[157]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Eplerenone	DMF0NQR	Heart failure	BD10-BD13	Approved	[158]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[159]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[160]
Voriconazole	DMAOL2S	Aspergillosis	1F20	Approved	[161]
Proguanil	DMBL79I	Malaria	1F40-1F45	Approved	[162]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[162]
Loratadine	DMF3AN7	Allergy	4A80-4A85	Approved	[163]
Nelfinavir mesylate	DMFX6G8	N. A.	N. A.	Approved	[164]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[165]
Axitinib	DMGVH6N	Renal cell carcinoma	2C90	Approved	[166]
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Drug(s) Affected By Cytochrome P450 3A5 (CYP3A5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Eplerenone	DMF0NQR	Heart failure	BD10-BD13	Approved	[158]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[159]
Nelfinavir mesylate	DMFX6G8	N. A.	N. A.	Approved	[164]
Ritonavir	DMU764S	Human immunodeficiency virus infection	1C62	Approved	[164]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[167]
Omeprazole	DM471KJ	Cystic fibrosis	CA25	Approved	[168]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[169]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[131]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[140]
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[170]
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Drug(s) Affected By Cytochrome P450 3A7 (CYP3A7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[36]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[131]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[168]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[171]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[172]
Phenobarbital	DMXZOCG	Cluster headache	8A81.0	Approved	[173]
Carbamazepine	DMZOLBI	Epilepsy	8A60-8A68	Approved	[174]
Prasterone	DM67VKL	Chronic obstructive pulmonary disease	CA22	Approved	[175]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[176]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[177]
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Drug(s) Affected By Flavin-containing monooxygenase 1 (FMO1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[53]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[178]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[179]
Nefazodone	DM4ZS8M	Major depressive disorder	6A70.3	Approved	[180]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[181]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[140]
Dihydroxyacetone	DMM1LG2	Sunburn	EJ40	Approved	[182]
Atazanavir	DMSYRBX	Human immunodeficiency virus infection	1C62	Approved	[180]
Cytarabine	DMZD5QR	Acute lymphoblastic leukaemia	2A85	Approved	[183]
Triclosan	DMZUR4N	Malaria	1F40-1F45	Approved	[184]
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⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
Cytochrome P450 2A6 (CYP2A6)^{Main DME}	DEJVYAZ	CP2A6_HUMAN	Substrate	[1]

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Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Acetylcholinesterase (ACHE)	OT2H8HG6	ACES_HUMAN	Gene/Protein Processing	[2]
Breast cancer type 1 susceptibility protein (BRCA1)	OT5BN6VH	BRCA1_HUMAN	Gene/Protein Processing	[3]
Cellular tumor antigen p53 (TP53)	OTIE1VH3	P53_HUMAN	Gene/Protein Processing	[4]
Cholinesterase (BCHE)	OTOH3WQ9	CHLE_HUMAN	Gene/Protein Processing	[5]
Cytochrome P450 3A4 (CYP3A4)	OTQGYY83	CP3A4_HUMAN	Regulation of Drug Effects	[6]
Cytochrome P450 3A5 (CYP3A5)	OTSXFBXB	CP3A5_HUMAN	Regulation of Drug Effects	[6]
Cytochrome P450 3A7 (CYP3A7)	OTTCDHHM	CP3A7_HUMAN	Regulation of Drug Effects	[6]
DNA repair protein RAD51 homolog 1 (RAD51)	OTNVWGC1	RAD51_HUMAN	Gene/Protein Processing	[3]
DNA repair protein XRCC2	OTJB2PV4	XRCC2_HUMAN	Gene/Protein Processing	[3]
E3 ubiquitin-protein ligase RAD18 (RAD18)	OTQ9PLNT	RAD18_HUMAN	Gene/Protein Processing	[3]

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