Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMM3950)

Drug Name
Sodium chloride Drug Info
Synonyms
sodium chloride; 7647-14-5; Halite; Salt; Table salt; Saline; Rock salt; Common salt; Dendritis; Purex; Sodium chloric; Top flake; Sodium chloride (NaCl); Hyposaline; Flexivial; Gingivyl; Iodized salt; Slow Sodium; Sea salt; SS salt; Sodium monochloride; Natriumchlorid; Hypersal; Adsorbanac; Trisodium trichloride; White crystal; NaCl; HG blending; Salt (ingredient); sodiumchloride; Colyte; Sodium chloride (Na4Cl4); Caswell No 754; Extra Fine 325 Salt; Extra Fine 200 Salt; Sodium chloride brine, purified; Arm-A-Vial; CCRIS 982; sterling
Indication
Disease Entry ICD 11 Status REF
Skin burns ME65.0 Approved [1]
Cross-matching ID
PubChem CID
5234
ChEBI ID
CHEBI:26710
CAS Number
CAS 7647-14-5
TTD Drug ID
DMM3950
VARIDT Drug ID
DR01173

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DOT
Drug Status:
Approved Drug(s)
Discontinued Drug(s)
Clinical Trial Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Adrenergic receptor Alpha-2 (ADRA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [2]
Meperidine DMX4GND Pain MG30-MG3Z Approved [9]
Lofexidine DM1WXA6 Heroin and opiate withdrawal 6C43 Approved [10]
Guanfacine extended release DMB1CZ8 Attention deficit hyperactivity disorder 6A05.Z Approved [11]
Dexmedetomidine DM93L4X Irritability MB24 Approved [12]
Yohimbine DMJCP1Y Erectile dysfunction HA01.1 Approved [13]
Guanabenz DM5QWEL High blood pressure BA00 Approved [14]
Tizanidine DMR2IQ4 Spasm MB47.3 Approved [15]
Oxymetazoline DM8ZXT6 Arrhythmia BC9Z Approved [16]
Brimonidine DMQLT4N Ocular hypertension 9C61.01 Approved [17]
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Drug(s) Transported By Organic cation transporter 3 (SLC22A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Angina pectoris BA40 Approved [18]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [19]
Metformin DM89QE1 Colorectal carcinoma Approved [20]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [18]
Entecavir DM7VTQO Hepatitis B virus infection 1E51.0 Approved [21]
Epinephrine DM3KJBC Acute asthma CA23 Approved [19]
Norepinephrine DMOUC09 Alopecia ED70 Approved [19]
Amphetamine DMSZQAK Attention deficit hyperactivity disorder 6A05.Z Approved [22]
Acetylcholine DMDF79Z Cataract 9B10 Approved [23]
Etilefrine DM67PWD Cardiovascular disease BA00-BE2Z Withdrawn from market [24]
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Drug(s) Transported By Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 (SLC12A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Potassium Chloride DMMTAJC Hypokalemia 5C77 Approved [25]
Drug(s) Transported By Basolateral Na-K-Cl symporter (SLC12A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Potassium Chloride DMMTAJC Hypokalemia 5C77 Approved [3]
Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [26]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Verapamil DMA7PEW Angina pectoris BA40 Approved [28]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [29]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [28]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Methotrexate DM2TEOL Anterior urethra cancer Approved [32]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [34]
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Drug(s) Affected By Collagen alpha-1(I) chain (COL1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [36]
Diazepam DM08E9O Alcohol withdrawal Approved [37]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [38]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [39]
Methotrexate DM2TEOL Anterior urethra cancer Approved [40]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [41]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [42]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [43]
Quercetin DM3NC4M Obesity 5B81 Approved [44]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [45]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [47]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [48]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [49]
Paclitaxel DMLB81S Breast carcinoma Approved [50]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [51]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [52]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [53]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [54]
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Drug(s) Affected By 72 kDa type IV collagenase (MMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Selenium DM25CGV N. A. N. A. Approved [56]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [57]
Quercetin DM3NC4M Obesity 5B81 Approved [58]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [59]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [60]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [61]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [62]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [63]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [64]
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Drug(s) Affected By Platelet-derived growth factor receptor beta (PDGFRB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [66]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [61]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [67]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Folic Acid DMEMBJC Colorectal carcinoma Approved [71]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [72]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [73]
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Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [74]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [75]
Gefitinib DM15F0X Colon adenocarcinoma Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [78]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [79]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [80]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [81]
Quercetin DM3NC4M Obesity 5B81 Approved [82]
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Drug(s) Affected By Platelet-derived growth factor receptor alpha (PDGFRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [83]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Panobinostat DM58WKG Chronic graft versus host disease Approved [85]
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [86]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Folic Acid DMEMBJC Colorectal carcinoma Approved [89]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [91]
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Drug(s) Affected By Protein kinase C alpha type (PRKCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [92]
Quercetin DM3NC4M Obesity 5B81 Approved [93]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Panobinostat DM58WKG Chronic graft versus host disease Approved [85]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [96]
Leflunomide DMR8ONJ Arthritis FA20 Approved [97]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [98]
Capsaicin DMGMF6V Back pain ME84.Z Approved [99]
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Drug(s) Affected By Tyrosine-protein phosphatase non-receptor type 6 (PTPN6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [65]
Selenium DM25CGV N. A. N. A. Approved [100]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Bortezomib DMNO38U Leukemia Approved [104]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [105]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [106]
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Drug(s) Affected By Caspase-2 (CASP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Methotrexate DM2TEOL Anterior urethra cancer Approved [109]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [111]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [112]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [113]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [114]
Leflunomide DMR8ONJ Arthritis FA20 Approved [97]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [115]
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Drug(s) Affected By Cytosolic phospholipase A2 (PLA2G4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [59]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [116]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Panobinostat DM58WKG Chronic graft versus host disease Approved [85]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Capsaicin DMGMF6V Back pain ME84.Z Approved [118]
Budesonide DMJIBAW Allergic rhinitis CA08.0 Approved [119]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [120]
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Drug(s) Affected By CCAAT/enhancer-binding protein alpha (CEBPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [121]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [125]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [126]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [114]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [103]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [126]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [127]
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Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [129]
Selenium DM25CGV N. A. N. A. Approved [100]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [130]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [131]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [132]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [135]
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Drug(s) Affected By Focal adhesion kinase 1 (PTK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [136]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [138]
Quercetin DM3NC4M Obesity 5B81 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [140]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [141]
Testosterone DM7HUNW Hot flushes GA30 Approved [142]
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [143]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
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Drug(s) Affected By Forkhead box protein O1 (FOXO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [144]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [145]
Quercetin DM3NC4M Obesity 5B81 Approved [146]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Panobinostat DM58WKG Chronic graft versus host disease Approved [85]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [147]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [148]
Leflunomide DMR8ONJ Arthritis FA20 Approved [97]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
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Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [149]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [150]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [151]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Gefitinib DM15F0X Colon adenocarcinoma Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [153]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [154]
Selenium DM25CGV N. A. N. A. Approved [100]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [155]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
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Drug(s) Affected By Nuclear factor of activated T-cells 5 (NFAT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [100]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [156]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [122]
Testosterone enanthate DMB6871 N. A. N. A. Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [127]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [158]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [105]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [159]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [160]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [161]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [78]
Prednisone DM2HG4X Acute asthma CA23 Approved [163]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [164]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [165]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
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Drug(s) Affected By Vasopressin-neurophysin 2-copeptin (AVP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [167]
Oxprenolol DM51OQW Anxiety Approved [168]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [170]
Luvox DMJKROX Anxiety disorder 6B00-6B0Z Approved [171]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [167]
Chlorpropamide DMPHZQE Non-insulin dependent diabetes 5A11 Approved [172]
Indomethacin DMSC4A7 Bursitis Approved [173]
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Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [175]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [175]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [176]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [175]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [177]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [128]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [178]
Gefitinib DM15F0X Colon adenocarcinoma Approved [179]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [175]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [181]
Selenium DM25CGV N. A. N. A. Approved [182]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [183]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [184]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [185]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [186]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [187]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [74]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [178]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [181]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [185]
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Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [189]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [189]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [35]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [190]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [191]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [192]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [193]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [194]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [195]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [80]
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Drug(s) Affected By Progesterone receptor (PGR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [196]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [197]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Estrone DM5T6US Acne vulgaris ED80 Approved [199]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [200]
Testosterone DM7HUNW Hot flushes GA30 Approved [201]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [202]
Goserelin DMAT8CG Breast cancer 2C60-2C65 Approved [203]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [204]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
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Drug(s) Affected By Fibroblast growth factor 2 (FGF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [205]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Diazepam DM08E9O Alcohol withdrawal Approved [37]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [206]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [8]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [207]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [208]
Isradipine DMA5XGH Hypertension BA00-BA04 Approved [209]
Valdecoxib DMAY7H4 Osteoarthritis FA00-FA05 Approved [210]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [211]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [212]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [213]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [187]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [214]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [178]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [175]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [215]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [216]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [27]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [217]
Gefitinib DM15F0X Colon adenocarcinoma Approved [218]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [219]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [220]
Etretinate DM2CZFA Keratosis ED56 Approved [221]
Prednisone DM2HG4X Acute asthma CA23 Approved [222]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [223]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [7]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium- and chloride-dependent betaine transporter (SLC6A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [224]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [226]
Leflunomide DMR8ONJ Arthritis FA20 Approved [97]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [105]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [227]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transforming growth factor beta-2 proprotein (TGFB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [228]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [94]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [229]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [230]
Testosterone DM7HUNW Hot flushes GA30 Approved [231]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [232]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [233]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proheparin-binding EGF-like growth factor (HBEGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [234]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [235]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [8]
Quercetin DM3NC4M Obesity 5B81 Approved [122]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [236]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [237]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [238]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [114]
Testosterone DM7HUNW Hot flushes GA30 Approved [231]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuron-specific vesicular protein calcyon (CALY)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [239]
Epinephrine DM3KJBC Acute asthma CA23 Approved [240]
Norepinephrine DMOUC09 Alopecia ED70 Approved [240]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [240]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [241]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Sodium/hydrogen exchanger 9B2 (SLC9B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Panobinostat DM58WKG Chronic graft versus host disease Approved [85]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [105]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [242]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [243]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [244]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [245]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [85]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [85]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor Alpha-2 (ADRA2) TTQ8AFT NOUNIPROTAC Agonist [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Basolateral Na-K-Cl symporter (SLC12A2) DTHKL3Q S12A2_HUMAN Substrate [3]
Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2 (SLC12A1) DTO1UQY S12A1_HUMAN Substrate [4]
Organic cation transporter 3 (SLC22A3) DT6201N S22A3_HUMAN Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [6]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Gene/Protein Processing [6]
Caspase-2 (CASP2) OTUDYSPP CASP2_HUMAN Gene/Protein Processing [6]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [6]
CCAAT/enhancer-binding protein alpha (CEBPA) OTOM9OE4 CEBPA_HUMAN Gene/Protein Processing [6]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [6]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Gene/Protein Processing [6]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Gene/Protein Processing [7]
Cytosolic phospholipase A2 (PLA2G4A) OTE70SOT PA24A_HUMAN Gene/Protein Processing [6]
Fibroblast growth factor 2 (FGF2) OT7YUJ9F FGF2_HUMAN Gene/Protein Processing [8]

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