Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMMG2TO)

Drug Name
D-glucose Drug Info
Synonyms
D-Glucopyranose; Glucopyranose; D-Glc; D-Glcp; Glucodin; Meritose; Clintose L; Roferose ST; CPC hydrate; Clearsweet 95; 2280-44-6; Staleydex 95M; CHEBI:4167; Glucopyranoside; D-Glucopyranoside; Glc; (3R,4S,5S,6R)-6-(hydroxymethyl)oxane-2,3,4,5-tetrol; Glucopyranose, D-; DSSTox_CID_2910; Glucose solution; D-Glucopyranose, anhydrous; glc-ring; D-glucose-ring; Cartose Cerelose; Staleydex 130; Glucose 40; EINECS 218-914-5; Meritose 200; Glc-OH
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
5793
ChEBI ID
CHEMBL1222250
CAS Number
CAS 2280-44-6
TTD Drug ID
DMMG2TO
VARIDT Drug ID
DR00165
INTEDE Drug ID
DR2081

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Transported By Glucose transporter type 1, erythrocyte/brain (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
dehydroascorbic acid DMKYQO4 Discovery agent N.A. Investigative [20]
Arsenite DMBCO4Q Discovery agent N.A. Investigative [21]
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [22]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [23]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [24]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [25]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [26]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
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Drug(s) Affected By 60 kDa heat shock protein, mitochondrial (HSPD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [31]
Etretinate DM2CZFA Keratosis ED56 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [34]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [40]
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Drug(s) Affected By Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [42]
Fructose DM43AN2 Vomiting MD90 Approved [43]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [44]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [45]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Ketotifen DM74XKS Allergic conjunctivitis 9A60.02 Approved [46]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [47]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [47]
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Drug(s) Affected By Oxidized low-density lipoprotein receptor 1 (OLR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [49]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [50]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [52]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [53]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [54]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [49]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [49]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [55]
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Drug(s) Affected By Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [58]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [59]
Methotrexate DM2TEOL Anterior urethra cancer Approved [60]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [61]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
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Drug(s) Affected By SPARC (SPARC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [68]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [69]
Ethanol DMDRQZU Chronic pain MG30 Approved [72]
Folic Acid DMEMBJC Colorectal carcinoma Approved [73]
Paclitaxel DMLB81S Breast carcinoma Approved [74]
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Drug(s) Affected By Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [76]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
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Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [81]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [82]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [83]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [84]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [85]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [86]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [87]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [88]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [89]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [87]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [90]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [91]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Gefitinib DM15F0X Colon adenocarcinoma Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [95]
Methotrexate DM2TEOL Anterior urethra cancer Approved [96]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [97]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [98]
Quercetin DM3NC4M Obesity 5B81 Approved [99]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Selenium DM25CGV N. A. N. A. Approved [101]
Methotrexate DM2TEOL Anterior urethra cancer Approved [102]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [103]
Epinephrine DM3KJBC Acute asthma CA23 Approved [104]
Quercetin DM3NC4M Obesity 5B81 Approved [105]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [76]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [107]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
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Drug(s) Affected By Small ribosomal subunit protein uS2 (RPSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [110]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [111]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [113]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [114]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [115]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
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Drug(s) Affected By Proteasome subunit alpha type-1 (PSMA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [117]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Benzatropine DMF7EXL Parkinsonian disorder Approved [25]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [118]
NVP-AUY922 DMTYXQF Multiple myeloma 2A83 Phase 2 [119]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [120]
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Drug(s) Affected By Aldehyde dehydrogenase X, mitochondrial (ALDH1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
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Drug(s) Affected By Alpha-soluble NSF attachment protein (NAPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [126]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [127]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [128]
[3H]methyltrienolone DMTSGOW Discovery agent N.A. Investigative [129]
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Drug(s) Affected By Protein SEC13 homolog (SEC13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [133]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [124]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [134]
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Drug(s) Affected By Actin, cytoplasmic 1 (ACTB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [124]
Etretinate DM2CZFA Keratosis ED56 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [135]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [136]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [136]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [137]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [138]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [139]
Etidronic acid DM1XHYJ Bone Paget disease Approved [136]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [136]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [136]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [140]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [141]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [142]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [143]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [144]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [145]
Cepharanthine DM9Y5JB N. A. N. A. Approved [146]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [147]
Clozapine DMFC71L Schizophrenia 6A20 Approved [148]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [149]
Trifluoperazine DMKBYWI Anxiety Approved [150]
Olanzapine DMPFN6Y Bipolar depression Approved [148]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Prednisone DM2HG4X Acute asthma CA23 Approved [152]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [154]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [155]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [156]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [157]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [158]
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Drug(s) Affected By NAD-dependent protein deacetylase sirtuin-3, mitochondrial (SIRT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [159]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [37]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [161]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [160]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [162]
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Drug(s) Affected By Transient receptor potential cation channel subfamily M member 7 (TRPM7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [163]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Magnesium DMU4ORS Ischemic stroke 8B11.5Z Approved [164]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [127]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [165]
methyl p-hydroxybenzoate DMO58UW Discovery agent N.A. Investigative [166]
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Drug(s) Affected By Hemoglobin subunit alpha (HBA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [167]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Folic Acid DMEMBJC Colorectal carcinoma Approved [169]
Flucloxacillin DMNUWST Bacterial infection 1A00-1C4Z Approved [170]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [171]
Orlistat DMRJSP8 Obesity 5B81 Approved [172]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [173]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
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Drug(s) Affected By Band 3 anion transport protein (SLC4A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
Adefovir DMM278X N. A. N. A. Approved [175]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [176]
CHLORIDE DM1TJXA Solid tumour/cancer 2A00-2F9Z Phase 3 [177]
AMG 386 DMQJXL4 Breast cancer 2C60-2C65 Phase 3 [178]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
Selenious acid DMB7GPA N. A. N. A. Investigative [180]
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Drug(s) Affected By Calpain-1 catalytic subunit (CAPN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [181]
Selenium DM25CGV N. A. N. A. Approved [124]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [182]
Quercetin DM3NC4M Obesity 5B81 Approved [183]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [184]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [185]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [186]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [187]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
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Drug(s) Affected By Copper transport protein ATOX1 (ATOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
CERC-801 DM3SZ7P N. A. N. A. Phase 2 [189]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [124]
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Drug(s) Affected By Dynamin-1-like protein (DNM1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [190]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [192]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [193]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Ethanol DMDRQZU Chronic pain MG30 Approved [194]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [195]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [190]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [196]
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Drug(s) Affected By ATP-dependent RNA helicase DDX3X (DDX3X)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [197]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [198]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [200]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [201]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [202]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Forkhead box protein O3 (FOXO3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [203]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Quercetin DM3NC4M Obesity 5B81 Approved [205]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [206]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [207]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calumenin (CALU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Benzatropine DMF7EXL Parkinsonian disorder Approved [25]
Clozapine DMFC71L Schizophrenia 6A20 Approved [25]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [133]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dynamin-like 120 kDa protein, mitochondrial (OPA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [208]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Selenium DM25CGV N. A. N. A. Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [193]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Ethanol DMDRQZU Chronic pain MG30 Approved [194]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [201]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By TBC1 domain family member 4 (TBC1D4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [210]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [211]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [212]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [213]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nephrin (NPHS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [214]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [215]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [216]
Bezafibrate DMZDCS0 Hypercholesterolaemia 5C80.0 Approved [217]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [219]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
PIRINIXIC ACID DM82Y75 Pulmonary fibrosis CB03.4 Preclinical [217]
Puromycin DMDKLB5 N. A. N. A. Preclinical [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gremlin-1 (GREM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [50]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [223]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [224]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [225]
Quercetin DM3NC4M Obesity 5B81 Approved [226]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [225]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [227]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [228]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [225]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein SNAI1 (SNAI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [229]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [230]
Quercetin DM3NC4M Obesity 5B81 Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [232]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [233]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [234]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [235]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome b (CYTB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [236]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [237]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [198]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Urethane DM7NSI0 N. A. N. A. Phase 4 [238]
Fialuridine DMCIGRB Hepatitis B virus infection 1E51.0 Phase 2 [239]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [240]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [241]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [242]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c oxidase subunit 2 (COX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [243]
Quercetin DM3NC4M Obesity 5B81 Approved [167]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [244]
Clarithromycin DM4M1SG Acute maxillary sinusitis Approved [245]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [246]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [247]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [245]
Menthol DMG2KW7 Back pain ME84.Z Approved [248]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [249]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Complement C1r subcomponent (C1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [211]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [250]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [251]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [252]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metalloproteinase inhibitor 1 (TIMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [253]
Verapamil DMA7PEW Angina pectoris BA40 Approved [254]
Selenium DM25CGV N. A. N. A. Approved [255]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [254]
Quercetin DM3NC4M Obesity 5B81 Approved [256]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [257]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [259]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [260]
Gefitinib DM15F0X Colon adenocarcinoma Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [262]
Selenium DM25CGV N. A. N. A. Approved [263]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [264]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [265]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [266]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [268]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [269]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [270]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [271]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [272]
Prednisone DM2HG4X Acute asthma CA23 Approved [273]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [274]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [275]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcitonin (CALCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [276]
Fructose DM43AN2 Vomiting MD90 Approved [277]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [278]
Folic Acid DMEMBJC Colorectal carcinoma Approved [169]
Nizatidine DMGFV3Z Acid-reflux disorder DA22 Approved [276]
Capsaicin DMGMF6V Back pain ME84.Z Approved [279]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(I) chain (COL1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Diazepam DM08E9O Alcohol withdrawal Approved [282]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [283]
Methotrexate DM2TEOL Anterior urethra cancer Approved [284]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [285]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [286]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [287]
Quercetin DM3NC4M Obesity 5B81 Approved [288]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(III) chain (COL3A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [289]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [290]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [291]
Quercetin DM3NC4M Obesity 5B81 Approved [292]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [293]
Testosterone DM7HUNW Hot flushes GA30 Approved [294]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [175]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [296]
Diazepam DM08E9O Alcohol withdrawal Approved [297]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [298]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [299]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [300]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [301]
Methotrexate DM2TEOL Anterior urethra cancer Approved [302]
Quercetin DM3NC4M Obesity 5B81 Approved [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [304]
Etretinate DM2CZFA Keratosis ED56 Approved [305]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [306]
Methotrexate DM2TEOL Anterior urethra cancer Approved [307]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [308]
Quercetin DM3NC4M Obesity 5B81 Approved [309]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [310]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [311]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [262]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sex hormone-binding globulin (SHBG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [312]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Fructose DM43AN2 Vomiting MD90 Approved [313]
Oxcarbazepine DM5PU6O Epilepsy 8A60-8A68 Approved [314]
Estrone DM5T6US Acne vulgaris ED80 Approved [315]
Testosterone DM7HUNW Hot flushes GA30 Approved [316]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [315]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [315]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock protein beta-1 (HSPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [208]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Selenium DM25CGV N. A. N. A. Approved [124]
Methotrexate DM2TEOL Anterior urethra cancer Approved [317]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [318]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [319]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [320]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome b-245 heavy chain (CYBB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [322]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Ethanol DMDRQZU Chronic pain MG30 Approved [323]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [121]
Dalcetrapib DMKNCVM Acute coronary syndrome BA41 Phase 3 [324]
Anacetrapib DMP2BFG Arteriosclerosis BD40 Phase 3 [324]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [325]
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Drug(s) Affected By Protein S100-A8 (S100A8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [326]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [327]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [326]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [328]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [328]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [50]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [246]
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [326]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [326]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen activator inhibitor 1 (SERPINE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [329]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [330]
Methotrexate DM2TEOL Anterior urethra cancer Approved [331]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [332]
Quercetin DM3NC4M Obesity 5B81 Approved [333]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [334]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [335]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [31]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [337]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [338]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [339]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [340]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [227]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [341]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 1 (FGF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [342]
Methotrexate DM2TEOL Anterior urethra cancer Approved [102]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [328]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [328]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [343]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [345]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [328]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [346]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [347]
Fructose DM43AN2 Vomiting MD90 Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [348]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [85]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [349]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [350]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [351]
Methotrexate DM2TEOL Anterior urethra cancer Approved [352]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [353]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [354]
Gefitinib DM15F0X Colon adenocarcinoma Approved [355]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [356]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [265]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [357]
Methotrexate DM2TEOL Anterior urethra cancer Approved [358]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [359]
Quercetin DM3NC4M Obesity 5B81 Approved [360]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A9 (S100A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [326]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [327]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [328]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [328]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [262]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [361]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [246]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [362]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-enolase (ENO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [363]
Etretinate DM2CZFA Keratosis ED56 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [364]
Quercetin DM3NC4M Obesity 5B81 Approved [365]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [366]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [367]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [368]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA excision repair protein ERCC-1 (ERCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [369]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [370]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [371]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [372]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-2(I) chain (COL1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [295]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [373]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-2(IV) chain (COL4A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [49]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [36]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [49]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-enolase (ENO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [375]
Estrone DM5T6US Acne vulgaris ED80 Approved [376]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [377]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [69]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [368]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [368]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [342]
Gefitinib DM15F0X Colon adenocarcinoma Approved [378]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [379]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [380]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [381]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [382]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [381]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [383]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [384]
Methotrexate DM2TEOL Anterior urethra cancer Approved [385]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein GLI2 (GLI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [386]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [387]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [319]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mast/stem cell growth factor receptor Kit (KIT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [388]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [389]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [390]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [391]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [278]
Ethanol DMDRQZU Chronic pain MG30 Approved [392]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [393]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [211]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 2 (SLC2A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [394]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [395]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [396]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [397]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arylamine N-acetyltransferase 2 (NAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [398]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [399]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [400]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [401]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [402]
Quercetin DM3NC4M Obesity 5B81 Approved [403]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [405]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [406]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(VI) chain (COL6A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [328]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [328]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [407]
Paclitaxel DMLB81S Breast carcinoma Approved [74]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [328]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-2(VI) chain (COL6A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [390]
Selenium DM25CGV N. A. N. A. Approved [124]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [407]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [408]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Paclitaxel DMLB81S Breast carcinoma Approved [74]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Creatine kinase B-type (CKB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [328]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [328]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [409]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [410]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [229]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [411]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [412]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [413]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [414]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [415]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c oxidase subunit 4 isoform 1, mitochondrial (COX4I1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [416]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [417]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [418]
Mitotane DMU1GX0 Adrenocortical carcinoma 2D11.Z Approved [419]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [420]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome b-245 light chain (CYBA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [421]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [422]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [423]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [318]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [424]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Gefitinib DM15F0X Colon adenocarcinoma Approved [425]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [426]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [272]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [427]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [428]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [429]
Quercetin DM3NC4M Obesity 5B81 Approved [430]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 5 (CCL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [349]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [431]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [432]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [433]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [434]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [435]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [436]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [437]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plastin-3 (PLS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Haloperidol DM96SE0 Delirium Approved [25]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Clozapine DMFC71L Schizophrenia 6A20 Approved [25]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [438]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [439]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [440]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [441]
Fructose DM43AN2 Vomiting MD90 Approved [43]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [237]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [44]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
Haloperidol DM96SE0 Delirium Approved [442]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [443]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [444]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metalloproteinase inhibitor 2 (TIMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [445]
Selenium DM25CGV N. A. N. A. Approved [255]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [446]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [257]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [130]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Tetracaine DM9J6C2 Spinal anesthesia MB40.3 Approved [447]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Quercetin DM3NC4M Obesity 5B81 Approved [448]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [449]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [450]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [448]
Bortezomib DMNO38U Leukemia Approved [451]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [448]
BAICALEIN DM4C7E6 Influenza virus infection 1E30-1E32 Phase 2 [448]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [452]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-6 alpha (ATF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [225]
Quercetin DM3NC4M Obesity 5B81 Approved [183]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [225]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [227]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [341]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [335]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [225]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [453]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [454]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(V) chain (COL5A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [373]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [54]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [455]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [456]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 5 (SLC2A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [457]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [396]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [449]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [210]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [458]
Mirtazapine DML53ZJ Depression 6A70-6A7Z Approved [442]
Methamphetamine DMPM4SK Anxiety Approved [459]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cofilin-1 (CFL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Etretinate DM2CZFA Keratosis ED56 Approved [32]
Quercetin DM3NC4M Obesity 5B81 Approved [365]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [460]
Haloperidol DM96SE0 Delirium Approved [25]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [461]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [49]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [462]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [380]
Methotrexate DM2TEOL Anterior urethra cancer Approved [463]
Epinephrine DM3KJBC Acute asthma CA23 Approved [464]
Quercetin DM3NC4M Obesity 5B81 Approved [22]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [465]
Fructose DM43AN2 Vomiting MD90 Approved [277]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [466]
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Drug(s) Affected By Metallothionein-3 (MT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [467]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [468]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Gallium nitrate DMF9O6B Hypercalcaemia 5B91.0 Approved [469]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [470]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [471]
Arsenic DMTL2Y1 N. A. N. A. Approved [472]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [473]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [474]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [475]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [476]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [477]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [478]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [479]
Gefitinib DM15F0X Colon adenocarcinoma Approved [480]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [481]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [159]
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Drug(s) Affected By Proteasome subunit beta type-5 (PSMB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Sibutramine DMFJTDI Obesity 5B81 Approved [482]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Ardeparin DMYRX8B Deep vein thrombosis BD71 Approved [483]
Bortezomib DMNO38U Leukemia Approved [484]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [485]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [124]
WP-1066 DMUGHWR Recurrent glioblastoma 2A00.00 Phase 1/2 [485]
MG-132 DMKA2YS N. A. N. A. Preclinical [486]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [487]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [474]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [488]
Paclitaxel DMLB81S Breast carcinoma Approved [489]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [490]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [473]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [175]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [476]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [477]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCN family member 2 (CCN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [342]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [57]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [102]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [491]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [449]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [492]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SHC-transforming protein 1 (SHC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [493]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [494]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Bortezomib DMNO38U Leukemia Approved [495]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [496]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sorcin (SRI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [497]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [200]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [498]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-5 (CDH5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [500]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [77]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [501]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [502]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [65]
Ethanol DMDRQZU Chronic pain MG30 Approved [503]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [504]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [505]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [348]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [506]
Quercetin DM3NC4M Obesity 5B81 Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [507]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [508]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [509]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [510]
Testosterone DM7HUNW Hot flushes GA30 Approved [511]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [512]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pulmonary surfactant-associated protein D (SFTPD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [513]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [293]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [514]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
Methotrexate DM2TEOL Anterior urethra cancer Approved [175]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [128]
paraquat DMR8O3X Discovery agent N.A. Investigative [515]
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Drug(s) Affected By Phosphoenolpyruvate carboxykinase, cytosolic (PCK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [516]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [517]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [518]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [519]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glucose-6-phosphatase catalytic subunit 1 (G6PC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Fluoxetine DM3PD2C Bipolar depression Approved [520]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [63]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [517]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [519]
Leflunomide DMR8ONJ Arthritis FA20 Approved [521]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [63]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [63]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [522]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor SOX-6 (SOX6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [390]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [523]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [514]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [65]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [65]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [219]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 20 (KRT20)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Arsenic DMTL2Y1 N. A. N. A. Approved [524]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [525]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [526]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [219]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
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Drug(s) Affected By Phospholipid hydroperoxide glutathione peroxidase GPX4 (GPX4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [527]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [528]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [529]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Gallium nitrate DMF9O6B Hypercalcaemia 5B91.0 Approved [469]
Trabectedin DMG3Y89 Leiomyosarcoma 2B58 Approved [530]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stress-70 protein, mitochondrial (HSPA9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [531]
Gallium nitrate DMF9O6B Hypercalcaemia 5B91.0 Approved [469]
Clozapine DMFC71L Schizophrenia 6A20 Approved [25]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [114]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [532]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [389]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [349]
Gefitinib DM15F0X Colon adenocarcinoma Approved [533]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [356]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [462]
Etretinate DM2CZFA Keratosis ED56 Approved [534]
Prednisone DM2HG4X Acute asthma CA23 Approved [152]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [382]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [535]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein Mpv17 (MPV17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [536]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Urethane DM7NSI0 N. A. N. A. Phase 4 [238]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [127]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [537]
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Drug(s) Affected By Malate dehydrogenase, cytoplasmic (MDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [167]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [461]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Benzatropine DMF7EXL Parkinsonian disorder Approved [25]
Clozapine DMFC71L Schizophrenia 6A20 Approved [25]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostaglandin-H2 D-isomerase (PTGDS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [221]
Selenium DM25CGV N. A. N. A. Approved [124]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [538]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [539]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [540]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [348]
Gefitinib DM15F0X Colon adenocarcinoma Approved [541]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [351]
Quercetin DM3NC4M Obesity 5B81 Approved [99]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [37]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [542]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [351]
Ethacrynic acid DM60QMR Edema MG29 Approved [543]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [354]
Gefitinib DM15F0X Colon adenocarcinoma Approved [544]
Prednisone DM2HG4X Acute asthma CA23 Approved [152]
Methotrexate DM2TEOL Anterior urethra cancer Approved [545]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [546]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [547]
Quercetin DM3NC4M Obesity 5B81 Approved [548]
Fluoxetine DM3PD2C Bipolar depression Approved [549]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [550]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [551]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [390]
Gefitinib DM15F0X Colon adenocarcinoma Approved [552]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [553]
Epinephrine DM3KJBC Acute asthma CA23 Approved [464]
Quercetin DM3NC4M Obesity 5B81 Approved [554]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [35]
Fructose DM43AN2 Vomiting MD90 Approved [277]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [555]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [556]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [557]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [558]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [560]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [561]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [367]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 10 (TNFSF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [562]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [49]
Selenium DM25CGV N. A. N. A. Approved [124]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [563]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [564]
Methotrexate DM2TEOL Anterior urethra cancer Approved [565]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [566]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [502]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pancreas/duodenum homeobox protein 1 (PDX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amiloride DMRTSGP Congestive heart failure BD10 Approved [567]
Arsenic DMTL2Y1 N. A. N. A. Approved [568]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [569]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [570]
Harmine DMPA5WD Discovery agent N.A. Patented [571]
Hexadecanoic acid DMWUXDZ Discovery agent N.A. Investigative [572]
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Drug(s) Affected By Gasdermin-D (GSDMD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [573]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [574]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [575]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [576]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [574]
Ropivacaine DMSPJG2 Anaesthesia 9A78.6 Approved [577]
Paclitaxel DMLB81S Breast carcinoma Approved [578]
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Drug(s) Affected By Eukaryotic initiation factor 4A-I (EIF4A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [197]
Methotrexate DM2TEOL Anterior urethra cancer Approved [33]
Quercetin DM3NC4M Obesity 5B81 Approved [365]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [579]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Paclitaxel DMLB81S Breast carcinoma Approved [580]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [581]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin, aortic smooth muscle (ACTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [302]
Quercetin DM3NC4M Obesity 5B81 Approved [231]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [582]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [583]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [584]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [319]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [585]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By General transcription factor II-I (GTF2I)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [586]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [587]
Paclitaxel DMLB81S Breast carcinoma Approved [588]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [589]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [321]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Disintegrin and metalloproteinase domain-containing protein 17 (ADAM17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [590]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Menthol DMG2KW7 Back pain ME84.Z Approved [591]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [592]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [593]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [594]
Arsenic DMTL2Y1 N. A. N. A. Approved [595]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A12 (S100A12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [565]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [361]
Arsenic DMTL2Y1 N. A. N. A. Approved [596]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
Miglitol DMXBQAM Diabetic complication 5A2Y Approved [597]
Arecoline DMFJZK3 Parkinson disease 8A00.0 Phase 1 [598]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
Milchsaure DM462BT Pruritus EC90 Investigative [599]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By RNA-binding protein 3 (RBM3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Ethanol DMDRQZU Chronic pain MG30 Approved [600]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [601]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c (CYCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [602]
Gefitinib DM15F0X Colon adenocarcinoma Approved [378]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [603]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [604]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [605]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [42]
Pefloxacin DM49IGF Gonococcal urethritis 1A70.0Y Approved [606]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor A, mitochondrial (TFAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [607]
Quercetin DM3NC4M Obesity 5B81 Approved [608]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [42]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [609]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [610]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [611]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [612]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [613]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [614]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [614]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [615]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [616]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [614]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [614]
Ethacrynic acid DM60QMR Edema MG29 Approved [614]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [614]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By POU domain, class 5, transcription factor 1 (POU5F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [230]
Quercetin DM3NC4M Obesity 5B81 Approved [617]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [618]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [491]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [518]
Testosterone DM7HUNW Hot flushes GA30 Approved [619]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [494]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [620]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [621]
Selenium DM25CGV N. A. N. A. Approved [124]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [622]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [98]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [623]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [624]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [625]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxiredoxin-1 (PRDX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [626]
Etretinate DM2CZFA Keratosis ED56 Approved [32]
Methotrexate DM2TEOL Anterior urethra cancer Approved [307]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [627]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [36]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [461]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tight junction protein ZO-1 (TJP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [628]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Methotrexate DM2TEOL Anterior urethra cancer Approved [307]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [319]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Ethanol DMDRQZU Chronic pain MG30 Approved [629]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [504]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sterol regulatory element-binding protein 2 (SREBF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [175]
Selenium DM25CGV N. A. N. A. Approved [124]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [630]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [631]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [319]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [632]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [633]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acetyl-CoA carboxylase 1 (ACACA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [634]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [225]
Quercetin DM3NC4M Obesity 5B81 Approved [22]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [631]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [237]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [635]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mothers against decapentaplegic homolog 4 (SMAD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [636]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [637]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [210]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Ethanol DMDRQZU Chronic pain MG30 Approved [638]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kelch-like ECH-associated protein 1 (KEAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gefitinib DM15F0X Colon adenocarcinoma Approved [639]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [640]
Selenium DM25CGV N. A. N. A. Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [641]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [575]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [368]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [368]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [368]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [461]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [642]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endoplasmic reticulum membrane sensor NFE2L1 (NFE2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [586]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [498]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [643]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [201]
Arsenic DMTL2Y1 N. A. N. A. Approved [644]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [514]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [645]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eukaryotic translation initiation factor 4H (EIF4H)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [646]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [213]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [647]
paraquat DMR8O3X Discovery agent N.A. Investigative [197]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [648]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [198]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [649]
Ciprofibrate DMGC5DB Hyperlipoproteinemia 5C80 Approved [650]
Capsaicin DMGMF6V Back pain ME84.Z Approved [651]
Sodium Acetate Anhydrous DMH21E0 Hyponatraemia 5C72 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myosin light chain kinase, smooth muscle (MYLK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [640]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [652]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [637]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mothers against decapentaplegic homolog 2 (SMAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [66]
Quercetin DM3NC4M Obesity 5B81 Approved [636]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [653]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [185]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [111]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [111]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 14 (MAPK14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [654]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [208]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [100]
Methotrexate DM2TEOL Anterior urethra cancer Approved [317]
Quercetin DM3NC4M Obesity 5B81 Approved [655]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [121]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [656]
Ethacrynic acid DM60QMR Edema MG29 Approved [543]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [657]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [658]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Occludin (OCLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [659]
Methotrexate DM2TEOL Anterior urethra cancer Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [660]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [661]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Thioguanine DM7NKEV Acute lymphocytic leukaemia 2B33.3 Approved [662]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ethanol DMDRQZU Chronic pain MG30 Approved [629]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diacylglycerol kinase delta (DGKD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [536]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [663]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [127]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [390]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Phosphoenolpyruvate carboxykinase , mitochondrial (PCK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [586]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [641]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [460]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [449]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Clozapine DMFC71L Schizophrenia 6A20 Approved [25]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [664]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [38]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Testosterone enanthate DMB6871 N. A. N. A. Approved [123]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By F-box/WD repeat-containing protein 12 (FBXW12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [210]
Drug(s) Affected By Mitofusin-1 (MFN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [243]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Ethanol DMDRQZU Chronic pain MG30 Approved [194]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [665]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [200]
Bortezomib DMNO38U Leukemia Approved [587]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (PREX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [210]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Arsenic DMTL2Y1 N. A. N. A. Approved [666]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [667]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytoglobin (CYGB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [668]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Arsenic DMTL2Y1 N. A. N. A. Approved [669]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [514]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
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Drug(s) Affected By Interactor protein for cytohesin exchange factors 1 (IPCEF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [53]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [218]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [670]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [120]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [127]
PMID27336223-Compound-5 DM6E50A N. A. N. A. Patented [53]
EUGENOL DM7US1H Discovery agent N.A. Patented [670]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [671]
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Drug(s) Affected By DNA repair endonuclease XPF (ERCC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [672]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [168]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [673]
Arsenic DMTL2Y1 N. A. N. A. Approved [674]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Bortezomib DMNO38U Leukemia Approved [451]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [675]
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Drug(s) Affected By Patatin-like phospholipase domain-containing protein 2 (PNPLA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [676]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [601]
Urethane DM7NSI0 N. A. N. A. Phase 4 [238]
Beta-caryophyllene DM7583A Pain MG30-MG3Z Phase 2 [677]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [678]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [679]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [680]
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Drug(s) Affected By NACHT, LRR and PYD domains-containing protein 3 (NLRP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Selenium DM25CGV N. A. N. A. Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [681]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [575]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [682]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [373]
Ethanol DMDRQZU Chronic pain MG30 Approved [683]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [326]
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Drug(s) Affected By Bile acid receptor (NR1H4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [640]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [684]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [685]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [686]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [335]
Nisoldipine DM7ISKJ Hypertension BA00-BA04 Approved [684]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [685]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [687]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
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Drug(s) Affected By Bifunctional polynucleotide phosphatase/kinase (PNKP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [688]
Selenium DM25CGV N. A. N. A. Approved [124]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [689]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
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Drug(s) Affected By Mitogen-activated protein kinase kinase kinase 5 (MAP3K5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [690]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [64]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [691]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [692]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [693]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [694]
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Drug(s) Affected By Serine/threonine-protein kinase PINK1, mitochondrial (PINK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [695]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [51]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [695]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ethanol DMDRQZU Chronic pain MG30 Approved [696]
Capsaicin DMGMF6V Back pain ME84.Z Approved [697]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [698]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [699]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [634]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [700]
Methotrexate DM2TEOL Anterior urethra cancer Approved [307]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [701]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [335]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [702]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [703]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [704]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [454]
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Drug(s) Affected By Mitochondrial fission factor (MFF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [240]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [647]
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Drug(s) Affected By MLX-interacting protein (MLXIP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [116]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [705]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [642]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [706]
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Drug(s) Affected By Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sodium Acetate Anhydrous DMH21E0 Hyponatraemia 5C72 Approved [14]
Methotrexate DM2TEOL Anterior urethra cancer Approved [267]
Fluoxetine DM3PD2C Bipolar depression Approved [707]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [110]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [63]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diablo IAP-binding mitochondrial protein (DIABLO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [208]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [380]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [192]
Quercetin DM3NC4M Obesity 5B81 Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [708]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [709]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [319]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
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Drug(s) Affected By Dual oxidase 2 (DUOX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [467]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [30]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [456]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [536]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [321]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
paraquat DMR8O3X Discovery agent N.A. Investigative [710]
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Drug(s) Affected By Dual oxidase 1 (DUOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [711]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [663]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [570]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [712]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [713]
paraquat DMR8O3X Discovery agent N.A. Investigative [714]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Sodium Acetate Anhydrous DMH21E0 Hyponatraemia 5C72 Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [195]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [715]
Urethane DM7NSI0 N. A. N. A. Phase 4 [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable tRNA(His) guanylyltransferase (THG1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [440]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [195]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
Milchsaure DM462BT Pruritus EC90 Investigative [599]
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Drug(s) Affected By Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [223]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [225]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [225]
Quercetin DM3NC4M Obesity 5B81 Approved [716]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [225]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [227]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [228]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [717]
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Drug(s) Affected By Death domain-associated protein 6 (DAXX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [390]
Quercetin DM3NC4M Obesity 5B81 Approved [647]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [718]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [719]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [720]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Bendamustine hydrochloride DMFH15Z leukaemia 2A60-2B33 Approved [721]
Menthol DMG2KW7 Back pain ME84.Z Approved [591]
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Drug(s) Affected By Lymphoid enhancer-binding factor 1 (LEF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethacrynic acid DM60QMR Edema MG29 Approved [722]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [510]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [637]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [723]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [724]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [725]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [726]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [321]
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Drug(s) Affected By Apoptosis-associated speck-like protein containing a CARD (PYCARD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [727]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [575]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ethanol DMDRQZU Chronic pain MG30 Approved [728]
Menthol DMG2KW7 Back pain ME84.Z Approved [591]
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Drug(s) Affected By Transcription factor 19 (TCF19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [729]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [730]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [210]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [250]
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Drug(s) Affected By Nuclear protein 1 (NUPR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [342]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [731]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [732]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [733]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [731]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [731]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Fluoxetine DM3PD2C Bipolar depression Approved [731]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [732]
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Drug(s) Affected By Pyruvate carboxylase, mitochondrial (PC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [106]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [28]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [538]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [734]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [125]
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Drug(s) Affected By Ras GTPase-activating protein-binding protein 1 (G3BP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Quercetin DM3NC4M Obesity 5B81 Approved [735]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [210]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [209]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [589]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By L-lactate dehydrogenase B chain (LDHB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [63]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [460]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [736]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [344]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [461]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [63]
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Drug(s) Affected By NAD(P) transhydrogenase, mitochondrial (NNT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [27]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [71]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Clozapine DMFC71L Schizophrenia 6A20 Approved [25]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [199]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [737]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [737]
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Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 9 (SLC2A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [390]
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Testosterone DM7HUNW Hot flushes GA30 Approved [78]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [405]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [131]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
Fructose DM43AN2 Vomiting MD90 Approved [738]
Urethane DM7NSI0 N. A. N. A. Phase 4 [238]
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Drug(s) Affected By Potassium voltage-gated channel subfamily D member 2 (KCND2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [404]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [739]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [404]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [374]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [740]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [740]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [321]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [741]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinol-binding protein 4 (RBP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [539]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [539]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [222]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [188]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [514]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 11 (SLC2A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [29]
Leflunomide DMR8ONJ Arthritis FA20 Approved [48]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [368]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [368]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [368]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [368]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [368]
Fructose DM43AN2 Vomiting MD90 Approved [738]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [92]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [562]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [124]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [586]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [227]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [228]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [335]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [717]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [742]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 2, facilitated glucose transporter member 7 (SLC2A7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [743]
Arsenic DMTL2Y1 N. A. N. A. Approved [499]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
Drug(s) Affected By Nuclear receptor subfamily 1 group I member 3 (NR1I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [744]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [559]
Artemether DM48QOT Malaria 1F40-1F45 Approved [745]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [746]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [335]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [747]
Estrone DM5T6US Acne vulgaris ED80 Approved [748]
Leflunomide DMR8ONJ Arthritis FA20 Approved [521]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Resistin (RETN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [749]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [750]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [751]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [752]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [753]
Vitamin B3 DMQVRZH Chronic renal failure GB61.Z Approved [754]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [179]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [755]
isobutylmethylxanthine DM46F5X Discovery agent N.A. Investigative [756]
Icosapentum DMF1CM7 N. A. N. A. Investigative [757]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycogen debranching enzyme (AGL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [41]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [758]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [79]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [70]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [80]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [112]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [39]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [132]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Sodium/glucose cotransporter 2 (SLC5A2) DTKNH2D SC5A2_HUMAN Substrate [2]
Glucose transporter type 1, erythrocyte/brain (SLC2A1) DTG3T6X GTR1_HUMAN Substrate [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
ADP-dependent glucokinase (ADPGK) DENZGO4 ADPGK_HUMAN Substrate [4]
Brain form hexokinase (HK1) DEDMAGE HXK1_HUMAN Substrate [5]
Alcohol dehydrogenase (ADH) DEKU5HL A4L2V0_LACRE Substrate [6] , [7]
D-Lactate dehydrogenase (ldhA) DEQUGC0 A0A1C7BXR3_PSEAI Substrate [8] , [9]
Alpha-glucosidase (aglA) DEAMSKV PAGL1_LACP3 Substrate [10]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial (HIBCH) OTU2VHWR HIBCH_HUMAN Protein Interaction/Cellular Processes [11]
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Gene/Protein Processing [12]
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Gene/Protein Processing [13]
Acetyl-coenzyme A synthetase 2-like, mitochondrial (ACSS1) OT6C1WQD ACS2L_HUMAN Gene/Protein Processing [14]
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) OTB1FZJU ACSA_HUMAN Gene/Protein Processing [14]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [15]
Actin, cytoplasmic 1 (ACTB) OT1MCP2F ACTB_HUMAN Gene/Protein Processing [16]
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [17]
Aldehyde dehydrogenase X, mitochondrial (ALDH1B1) OTXW9TE2 AL1B1_HUMAN Gene/Protein Processing [16]
Alpha-enolase (ENO1) OTB1KWJS ENOA_HUMAN Protein Interaction/Cellular Processes [11]

References

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