General Information of Drug (ID: DMMN36E)

Drug Name
Abacavir Drug Info
Synonyms
Trizivir; Ziagen; Abacavir [INN]; Abacavir (INN); Ziagen (TN); Ziagen (TM)(*Succinate salt*); [(1S,4R)-4-[2-amino-6-(cyclopropylamino)purin-9-yl]cyclopent-2-en-1-yl]methanol; {(1S-cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol; (+/-)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; (+/-)-Abacavir; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol; ABC
Indication
Disease Entry ICD 11 Status REF
Human immunodeficiency virus infection 1C62 Approved [1]
Therapeutic Class
Anti-HIV Agents
Cross-matching ID
PubChem CID
441300
ChEBI ID
CHEBI:421707
CAS Number
CAS 136470-78-5
TTD Drug ID
DMMN36E
VARIDT Drug ID
DR00588
INTEDE Drug ID
DR0027
ACDINA Drug ID
D00002

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [15]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [16]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [17]
Tenofovir DM1IS6U Chronic hepatitis B virus infection Approved [15]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [18]
Delavirdine DM3NF5G Human immunodeficiency virus infection 1C62 Approved [18]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [18]
Rilpivirine DMJ0QOW Human immunodeficiency virus infection 1C62 Approved [19]
Etravirine DMGV8QU Human immunodeficiency virus-1 infection 1C62 Approved [20]
MK-1439 DM215WE Human immunodeficiency virus infection 1C62 Approved [21]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [3]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [23]
Folic Acid DMEMBJC Colorectal carcinoma Approved [24]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [23]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [23]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [25]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [23]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [26]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [27]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Folic Acid DMEMBJC Colorectal carcinoma Approved [30]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [31]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [32]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [33]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [34]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [33]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [35]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [36]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [37]
Folic Acid DMEMBJC Colorectal carcinoma Approved [38]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [40]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [3]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [41]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [42]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [43]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [44]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [3]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [45]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [46]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [47]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [48]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [49]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [50]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [51]
Metronidazole DMTIVEN Abscess Approved [52]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [53]
Ethanol DMDRQZU Chronic pain MG30 Approved [54]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [55]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [56]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [59]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [57]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [60]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [61]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [62]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [63]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [64]
NADH DM5NM6E Parkinson disease 8A00.0 Approved [65]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [66]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [67]
Allopurinol DMLPAOB Gout FA25 Approved [68]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [71]
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [72]
Flucloxacillin DMNUWST Bacterial infection 1A00-1C4Z Approved [73]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [74]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [75]
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Drug(s) Affected By C-reactive protein (CRP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [76]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [77]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [78]
Quercetin DM3NC4M Obesity 5B81 Approved [79]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [80]
Acalabrutinib DM7GCVW leukaemia 2A60-2B33 Approved [81]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [82]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [83]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [84]
Testosterone DM7HUNW Hot flushes GA30 Approved [85]
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Drug(s) Affected By Myeloperoxidase (MPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dapsone DM4LT8A Acne vulgaris ED80 Approved [76]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [86]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [76]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [87]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [88]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [89]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [90]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [91]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [92]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [93]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [94]
Gefitinib DM15F0X Colon adenocarcinoma Approved [95]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [96]
Selenium DM25CGV N. A. N. A. Approved [97]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [98]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [99]
Methotrexate DM2TEOL Anterior urethra cancer Approved [100]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [101]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [102]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [103]
Gefitinib DM15F0X Colon adenocarcinoma Approved [104]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [105]
Selenium DM25CGV N. A. N. A. Approved [106]
Quercetin DM3NC4M Obesity 5B81 Approved [107]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [108]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [109]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [111]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Panobinostat DM58WKG Chronic graft versus host disease Approved [113]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [114]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
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Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [115]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [76]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [116]
Diazepam DM08E9O Alcohol withdrawal Approved [117]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [118]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [119]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [120]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [121]
Methotrexate DM2TEOL Anterior urethra cancer Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [123]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [124]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [10]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [125]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [126]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [127]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [128]
Ethacrynic acid DM60QMR Edema MG29 Approved [129]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [130]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [131]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [132]
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Drug(s) Affected By Synaptophysin (SYP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [134]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [135]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Ethanol DMDRQZU Chronic pain MG30 Approved [136]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [134]
Methamphetamine DMPM4SK Anxiety Approved [137]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [138]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [139]
Urethane DM7NSI0 N. A. N. A. Phase 4 [140]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Testosterone enanthate DMB6871 N. A. N. A. Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [144]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [145]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [146]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [67]
Allopurinol DMLPAOB Gout FA25 Approved [147]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [69]
Ticlopidine DMO946V Acute coronary syndrome BA41 Approved [148]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [133]
Selenium DM25CGV N. A. N. A. Approved [149]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [151]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [152]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Penicillin V DMKVOYF Acute otitis media AB00 Approved [76]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [76]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [153]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [154]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [155]
Testosterone DM7HUNW Hot flushes GA30 Approved [85]
Haloperidol DM96SE0 Delirium Approved [156]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [158]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [159]
Methotrexate DM2TEOL Anterior urethra cancer Approved [160]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [161]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [164]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Panobinostat DM58WKG Chronic graft versus host disease Approved [113]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [165]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Folic Acid DMEMBJC Colorectal carcinoma Approved [166]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [167]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [168]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Panobinostat DM58WKG Chronic graft versus host disease Approved [113]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [163]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [170]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
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Drug(s) Affected By Homeobox protein MOX-1 (MEOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [171]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Panobinostat DM58WKG Chronic graft versus host disease Approved [113]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [172]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [173]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [174]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [141]
Panobinostat DM58WKG Chronic graft versus host disease Approved [113]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Dolutegravir DMCZGRE Human immunodeficiency virus infection 1C62 Approved [175]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Folic Acid DMEMBJC Colorectal carcinoma Approved [166]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [176]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [176]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [10]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [178]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [179]
Estrone DM5T6US Acne vulgaris ED80 Approved [180]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [181]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [182]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [183]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [184]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [185]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [167]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Ethanol DMDRQZU Chronic pain MG30 Approved [186]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
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Drug(s) Affected By Eyes absent homolog 1 (EYA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [187]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [189]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [11]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Panobinostat DM58WKG Chronic graft versus host disease Approved [113]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurogenin-2 (NEUROG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [11]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [11]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [11]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [11]
Leflunomide DMR8ONJ Arthritis FA20 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [70]
Dabigatran DMDI6R4 Stroke 8B20 Approved [11]
Folic Acid DMEMBJC Colorectal carcinoma Approved [167]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-4 (IL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [191]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [192]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [193]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [194]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [195]
Prednisone DM2HG4X Acute asthma CA23 Approved [196]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [197]
Methotrexate DM2TEOL Anterior urethra cancer Approved [174]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [198]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [199]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flucloxacillin DMNUWST Bacterial infection 1A00-1C4Z Approved [73]
Allopurinol DMLPAOB Gout FA25 Approved [200]
Pazopanib DMF57DM N. A. N. A. Approved [201]

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Human immunodeficiency virus Reverse transcriptase (HIV RT) TT84ETX POL_HV1B1 Inhibitor [2]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance-associated protein 4 (ABCC4) DTCSGPB MRP4_HUMAN Substrate [3]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [4]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [5]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [6]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DEB3CV1 UD2B7_HUMAN Substrate [7]
Alcohol dehydrogenase class-V (ADH6) DE017IC ADH6_HUMAN Substrate [6]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Albumin (ALB) OTVMM513 ALBU_HUMAN Protein Interaction/Cellular Processes [8]
C-reactive protein (CRP) OT0RFT8F CRP_HUMAN Gene/Protein Processing [9]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Gene/Protein Processing [10]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Gene/Protein Processing [10]
Eyes absent homolog 1 (EYA1) OTHU807A EYA1_HUMAN Gene/Protein Processing [11]
Fibroblast growth factor 8 (FGF8) OTFU0IUW FGF8_HUMAN Gene/Protein Processing [11]
Forkhead box protein C2 (FOXC2) OT83P1E0 FOXC2_HUMAN Gene/Protein Processing [11]
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Gene/Protein Processing [12]
HLA class I histocompatibility antigen protein P5 (HCP5) OTV0YRI8 HCP5_HUMAN Drug Response [13]
HLA class I histocompatibility antigen, B alpha chain (HLA-B) OTNXFWY2 HLAB_HUMAN Drug Response [14]

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