Details of Disease

General Information of Disease (ID: DISHL1EY)

Disease Name Post-traumatic stress disorder
Synonyms combat neurosis; traumatic neurosis; post-traumatic stress disorder; PTSD
Disease Class 6B40: Post-traumatic stress disorder
Definition
An anxiety disorder precipitated by an experience of intense fear or horror while exposed to a traumatic (especially life-threatening) event. The disorder is characterized by intrusive recurring thoughts or images of the traumatic event; avoidance of anything associated with the event; a state of hyperarousal and diminished emotional responsiveness. These symptoms are present for at least one month and the disorder is usually long-term.
Disease Hierarchy
DIS1YCE9: Neurotic disorder
DISHL1EY: Post-traumatic stress disorder
ICD Code
ICD-11
ICD-11: 6B40
ICD-10
ICD-10: F43.1, F62.0
ICD-9
ICD-9: 309.81
Expand ICD-11
'6B40
Expand ICD-10
'F43.1; 'F62.0
Expand ICD-9
309.81
Disease Identifiers
MONDO ID
MONDO_0005146
MESH ID
D013313
UMLS CUI
C0038436
MedGen ID
21345
SNOMED CT ID
47505003

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 2 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Paroxetine DM5PVQE Approved Small molecular drug [1]
Sertraline DM0FB1J Approved Small molecular drug [2]
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This Disease is Treated as An Indication in 7 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
TNX-102 DMO1234 Phase 3 Small molecular drug [3]
NBTX-001 DM3MJUS Phase 2/3 NA [4]
Nepicastat oral DMNM9DZ Phase 2 Small molecular drug [5]
NYX-783 DMAVM2E Phase 2 Small molecular drug [6]
PRX-3140 DMEVXS1 Phase 2 NA [7]
SRX-246 DMMU41F Phase 2 Small molecular drug [3]
SRX246 DMKOTUJ Phase 2 Small molecular drug [8]
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⏷ Show the Full List of 7 Drug(s)
This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CM-2236 DMP9EJ7 Preclinical NA [9]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 70 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ADCYAP1R1 TT5OREU Limited Biomarker [10]
APOE TTKS9CB Limited Biomarker [11]
CD160 TTOFEAS Limited Altered Expression [12]
CFP TTLA0VS Limited Biomarker [13]
CHRNA5 TTH2QRX Limited Biomarker [14]
CHRNB4 TTTVAFQ Limited Biomarker [14]
CPT1B TTDL0NY Limited Altered Expression [15]
CRH TTA7YIZ Limited Biomarker [16]
CRHR1 TT7EFHR Limited Genetic Variation [17]
DLG4 TT9PB26 Limited Biomarker [18]
ENPEP TT9PBIL Limited Biomarker [19]
FLT4 TTDCBX5 Limited Biomarker [17]
GRM5 TTHS256 Limited Altered Expression [20]
GSS TTVEWR4 Limited Genetic Variation [21]
HCRTR1 TT60Q8D Limited Genetic Variation [22]
HTR2C TTWJBZ5 Limited Biomarker [23]
HTR3A TTPC4TU Limited Genetic Variation [24]
IDS TTNY2AP Limited Biomarker [25]
MFGE8 TT1GLAJ Limited Biomarker [26]
NPSR1 TTV1C0Z Limited Genetic Variation [27]
NPY TT64REZ Limited Biomarker [28]
NR3C1 TTOZRK6 Limited Biomarker [29]
OPRK1 TTQW87Y Limited Biomarker [30]
PKD2L1 TTAHD89 Limited Biomarker [17]
RTN4 TT7GXMU Limited Biomarker [31]
SLC1A1 TTG2A6F Limited Genetic Variation [32]
SLC6A1 TTPRKM0 Limited Biomarker [33]
SRD5A2 TTT02K8 Limited Genetic Variation [34]
SRR TTZFUY6 Limited Genetic Variation [35]
TDO2 TTXNCBV Limited Genetic Variation [36]
TPH1 TTZSJHV Limited Genetic Variation [37]
UGCG TTPHEX3 Limited Biomarker [38]
ADCYAP1 TTW4LYC moderate Biomarker [39]
VIPR2 TT4O5P0 moderate Genetic Variation [40]
ADRA2B TTWM4TY Strong Genetic Variation [41]
BAX TTQ57WJ Strong Biomarker [42]
CASP9 TTB6T7O Strong Biomarker [43]
CRHR2 TTIY658 Strong Genetic Variation [17]
DBH TTYIP79 Strong Altered Expression [44]
DRD3 TT4C8EA Strong Biomarker [45]
DRD4 TTE0A2F Strong Genetic Variation [46]
EIF2AK3 TT79U1M Strong Biomarker [47]
ELK3 TT5OJMV Strong Biomarker [48]
ERN1 TTKIAT3 Strong Biomarker [47]
FKBP4 TTHY0FT Strong Biomarker [49]
GAD1 TTKGEP3 Strong Genetic Variation [27]
GRM2 TTXJ47W Strong Biomarker [50]
HCN1 TTNB6UQ Strong Altered Expression [51]
HCRT TTU5HJP Strong Biomarker [52]
HSPA5 TTW26OG Strong Biomarker [43]
HTR1A TTSQIFT Strong Biomarker [53]
HTR2A TTJQOD7 Strong Biomarker [54]
MAP3K10 TT9FN4J Strong Biomarker [55]
MDM2 TT9TE0O Strong Biomarker [56]
NTF4 TTIM2WO Strong Altered Expression [57]
NTRK2 TTKN7QR Strong Biomarker [58]
OPRL1 TTNT7K8 Strong Biomarker [59]
OXTR TTSCIUP Strong Genetic Variation [60]
POR TTOQ9GZ Strong Biomarker [61]
REG3A TTL4H8N Strong Biomarker [62]
RORA TT1TYN7 Strong Genetic Variation [63]
SGK1 TTTV8EJ Strong Altered Expression [64]
SLC18A2 TTNZRI3 Strong Altered Expression [65]
SLC26A4 TT7X02I Strong Genetic Variation [66]
SLC6A3 TTVBI8W Strong Genetic Variation [67]
TACR1 TTZPO1L Strong Biomarker [68]
TEC TT1ZV49 Strong Biomarker [69]
TPH2 TT3KLDP Strong Genetic Variation [70]
TUSC2 TTJ8O14 Strong Biomarker [62]
FABP3 TT3TGLR Definitive Biomarker [71]
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⏷ Show the Full List of 70 DTT(s)
This Disease Is Related to 5 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
SCLY DEH4TD6 Limited Biomarker [72]
ACP3 DEDW5H6 Strong Biomarker [62]
DHRS9 DEGTU5I Strong Biomarker [73]
FAAH DEUM1EX Strong Biomarker [74]
PTGDS DER3H9C Strong Genetic Variation [66]
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This Disease Is Related to 111 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACSM3 OT0AE1IV Limited Biomarker [75]
ADCY8 OTR1WCZX Limited Genetic Variation [76]
AMY1A OT6G4B8O Limited Altered Expression [77]
ANKK1 OT0OM1O0 Limited Genetic Variation [78]
ARSI OTIANNWW Limited Genetic Variation [79]
ATP8 OTYQQR53 Limited Genetic Variation [80]
BCS1L OT5PY5CY Limited Biomarker [81]
CANX OTYP1F6J Limited Biomarker [82]
CAPS OTC9GZ2M Limited Biomarker [83]
CAVIN2 OTFHHDRU Limited Genetic Variation [66]
CCL13 OTNX0JD0 Limited Biomarker [84]
CELA2A OTY8QG2J Limited Biomarker [85]
CENPJ OTZCQZN5 Limited Biomarker [62]
COPE OTBKHBT7 Limited Biomarker [86]
CORT OTX3GUHB Limited Biomarker [87]
CYRIB OTLRN4L1 Limited Genetic Variation [88]
DNASE1L3 OTEUIMC2 Limited Biomarker [89]
DOCK2 OTZTS3PA Limited Genetic Variation [90]
EGR3 OTGPJIRA Limited Biomarker [91]
ERAL1 OTSH78HD Limited Biomarker [92]
ETV3 OTEN03BM Limited Biomarker [85]
FXYD1 OTNKT6GP Limited Biomarker [93]
GABRB3 OT80C3D4 Limited Genetic Variation [94]
HGS OTCYYCAC Limited Biomarker [95]
IMPACT OTQ923OB Limited Genetic Variation [96]
LHX2 OTK61NP8 Limited Genetic Variation [97]
LY6E OTMG16BZ Limited Biomarker [98]
MAN2C1 OT17VT8D Limited Posttranslational Modification [99]
MARCHF11 OTODNSYN Limited Genetic Variation [100]
MCIDAS OTK1JVAH Limited Biomarker [101]
MOCOS OT0TL3Q5 Limited Genetic Variation [102]
MPI OTBH6ZK1 Limited Biomarker [103]
NARS1 OTFS4J1W Limited Genetic Variation [104]
ND5 OT45LW1K Limited Genetic Variation [80]
NFATC4 OTTDCUAO Limited Biomarker [105]
OR11L1 OTBUQ88D Limited Genetic Variation [106]
OR2L13 OTEE9SZP Limited Genetic Variation [106]
PDZD8 OTCQYNBU Limited Genetic Variation [107]
PNN OT0HXICH Limited Genetic Variation [108]
PSD OTUZIXUZ Limited Biomarker [109]
PTPN4 OT6SXU5Y Limited Biomarker [110]
PTS OTTYWQXR Limited Biomarker [111]
RIN1 OTPBROUD Limited Biomarker [112]
RRS1 OTTNCZN6 Limited Genetic Variation [113]
SHANK1 OTK8PV0S Limited Altered Expression [114]
SMCP OTXKY794 Limited Genetic Variation [102]
SNRPD1 OTWKZV4E Limited Genetic Variation [115]
SPNS1 OTSJ3BJ2 Limited Genetic Variation [104]
SRPX OT5B9LXS Limited Genetic Variation [108]
SRSF8 OTHFCYTK Limited Biomarker [116]
SYNM OTOI8TRJ Limited Biomarker [117]
TBC1D2 OTSGHPD0 Limited Genetic Variation [118]
TIA1 OTGPN3P8 Limited Biomarker [119]
TLE2 OT2KSZ9B Limited Biomarker [120]
TNFRSF10C OTVHOL9B Limited Biomarker [121]
TRIT1 OTCU9FS5 Limited Biomarker [122]
DTNBP1 OT9UQT2S moderate Genetic Variation [123]
ANK3 OTJ3IRBP Strong Biomarker [124]
ANKRD55 OT62KZII Strong Genetic Variation [125]
ARSD OTAHW9M8 Strong Biomarker [126]
ASAP1 OT4DLRYY Strong Biomarker [62]
ASAP2 OTGEXULW Strong Biomarker [62]
C1QL1 OTNQ0G3E Strong Biomarker [16]
CAMK2G OTHD9KJG Strong Altered Expression [127]
CASP12 OTY2W6FG Strong Biomarker [43]
CCL16 OTOOQI1F Strong Genetic Variation [128]
CCL4L2 OTDBSXOU Strong Biomarker [129]
CNTN3 OTC1274J Strong Biomarker [102]
CSTA OT1K68KE Strong Biomarker [130]
DBT OT4KZ5R9 Strong Biomarker [131]
DPYS OTLTUIVL Strong Biomarker [73]
DUSP2 OTH54FMR Strong Biomarker [132]
EBPL OT59J1GY Strong Biomarker [48]
EDEM1 OTWHN69S Strong Altered Expression [133]
ENDOU OTB7OF7Y Strong Altered Expression [134]
EXOSC6 OTAC10N6 Strong Altered Expression [134]
FMN2 OTUY7BSV Strong Biomarker [135]
INO80C OTKXHGET Strong Genetic Variation [136]
KLF6 OTQY9S7F Strong Biomarker [132]
KRT7 OTLT3JFN Strong Genetic Variation [137]
LPP OT6TU8SE Strong Biomarker [138]
LTBP3 OTME98V7 Strong Biomarker [139]
MPST OTCDPH5D Strong Biomarker [55]
MRPS30 OTDXIAGG Strong Biomarker [62]
MSTO1 OT37XCNP Strong Biomarker [55]
MTPAP OT6HQ02S Strong Biomarker [62]
MZB1 OT071TET Strong Biomarker [10]
NLGN1 OTGHRRFQ Strong Biomarker [140]
NOL3 OT1K0L0D Strong Biomarker [59]
NOS1AP OTDFOBRU Strong Altered Expression [141]
NPS OTEG25A2 Strong Biomarker [142]
OGN OTKP5S4L Strong Biomarker [143]
PAPOLA OTPHD65D Strong Biomarker [62]
PDAP1 OTJSWMOD Strong Biomarker [62]
PDIA3 OTHPQ0Q3 Strong Biomarker [82]
PDSS1 OTXGVHAB Strong Biomarker [144]
PHLDA2 OTMV9DPP Strong Biomarker [145]
PNOC OTJEAADN Strong Biomarker [59]
PPM1F OTU0MVR7 Strong Biomarker [146]
PPP1R3B OTVCRXEZ Strong Biomarker [147]
PPP1R3C OTEU05TX Strong Biomarker [147]
PRTFDC1 OTKJ44KY Strong Genetic Variation [97]
PSMG1 OTZ5I6UM Strong Biomarker [132]
REM1 OTUXL0HC Strong Altered Expression [148]
RPS19 OTBKGP48 Strong Biomarker [149]
S100A10 OTI71243 Strong Altered Expression [134]
SMS OT8JYKNH Strong Biomarker [144]
TAL1 OTX4K6QZ Strong Genetic Variation [137]
TBX4 OTW58FG4 Strong Biomarker [144]
TLL1 OTK9NM7G Strong Genetic Variation [88]
TSC22D3 OT03UM03 Strong Altered Expression [150]
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⏷ Show the Full List of 111 DOT(s)

References

1 Paroxetine FDA Label
2 Sertraline FDA Label
3 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
4 ClinicalTrials.gov (NCT03635827) Xenon Inhalation for Treatment of Posttraumatic Stress Disorder. U.S. National Institutes of Health.
5 ClinicalTrials.gov (NCT00641511) Pharmacogenetic Clinical Trial of Nepicastat for Post Traumatic Stress Disorder (PTSD). U.S. National Institutes of Health.
6 ClinicalTrials.gov (NCT04044664) Safety and Efficacy of NYX-783 in Subjects With Post-Traumatic Stress Disorder. U.S. National Institutes of Health.
7 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800021864)
8 ClinicalTrials.gov (NCT02733614) Proof-of-concept Study to Assess the Efficacy and Safety of SRX246 in Adults With PTSD. U.S. National Institutes of Health.
9 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800029346)
10 Pituitary adenylate cyclase-activating polypeptide (PACAP) signaling in the prefrontal cortex modulates cued fear learning, but not spatial working memory, in female rats.Neuropharmacology. 2018 May 1;133:145-154. doi: 10.1016/j.neuropharm.2018.01.010. Epub 2018 Jan 17.
11 Amyloid-, Tau, and 18F-Fluorodeoxyglucose Positron Emission Tomography in Posttraumatic Stress Disorder.J Alzheimers Dis. 2020;73(1):163-173. doi: 10.3233/JAD-190913.
12 Overlapping expression of serotonin transporters and neurokinin-1 receptors in posttraumatic stress disorder: a multi-tracer PET study.Mol Psychiatry. 2016 Oct;21(10):1400-7. doi: 10.1038/mp.2015.180. Epub 2015 Dec 1.
13 Dynamic causal modeling in PTSD and its dissociative subtype: Bottom-up versus top-down processing within fear and emotion regulation circuitry.Hum Brain Mapp. 2017 Nov;38(11):5551-5561. doi: 10.1002/hbm.23748. Epub 2017 Aug 24.
14 Effect of genetic variation in the nicotinic receptor genes on risk for posttraumatic stress disorder.Psychiatry Res. 2015 Sep 30;229(1-2):326-31. doi: 10.1016/j.psychres.2015.07.002. Epub 2015 Jul 8.
15 Mitochondria-focused gene expression profile reveals common pathways and CPT1B dysregulation in both rodent stress model and human subjects with PTSD.Transl Psychiatry. 2015 Jun 16;5(6):e580. doi: 10.1038/tp.2015.65.
16 Psychophysiological treatment outcomes: Corticotropin-releasing factor type 1 receptor antagonist increases inhibition of fear-potentiated startle in PTSD patients.Psychophysiology. 2020 Jan;57(1):e13356. doi: 10.1111/psyp.13356. Epub 2019 Feb 26.
17 Correlation between hypothalamic-pituitary-adrenal axis gene polymorphisms and posttraumatic stress disorder symptoms.Horm Behav. 2020 Jan;117:104604. doi: 10.1016/j.yhbeh.2019.104604. Epub 2019 Nov 6.
18 PSD95 and nNOS interaction as a novel molecular target to modulate conditioned fear: relevance to PTSD.Transl Psychiatry. 2018 Aug 14;8(1):155.
19 Examining various subthreshold definitions of PTSD using the Clinician Administered PTSD Scale for DSM-5.J Affect Disord. 2018 Jul;234:256-260. doi: 10.1016/j.jad.2018.03.001. Epub 2018 Mar 7.
20 Metabotropic Glutamatergic Receptor 5 and Stress Disorders: Knowledge Gained From Receptor Imaging Studies.Biol Psychiatry. 2018 Jul 15;84(2):95-105. doi: 10.1016/j.biopsych.2017.08.025. Epub 2017 Sep 19.
21 Factors Associated With Posttraumatic Stress Disorder Symptomology Among Women Who Have Experienced Sexual Assault in Canada.J Interpers Violence. 2021 Sep;36(17-18):NP9777-NP9795. doi: 10.1177/0886260519860084. Epub 2019 Jul 9.
22 The preliminary investigation of orexigenic hormone gene polymorphisms on posttraumatic stress disorder symptoms.Psychoneuroendocrinology. 2019 Feb;100:131-136. doi: 10.1016/j.psyneuen.2018.09.042. Epub 2018 Oct 2.
23 Increased 5-HT2C receptor editing predisposes to PTSD-like behaviors and alters BDNF and cytokines signaling.Transl Psychiatry. 2019 Feb 21;9(1):100. doi: 10.1038/s41398-019-0431-8.
24 The association of serotonin receptor 3A methylation with maternal violence exposure, neural activity, and child aggression.Behav Brain Res. 2017 May 15;325(Pt B):268-277. doi: 10.1016/j.bbr.2016.10.009. Epub 2016 Oct 5.
25 A survey of the experiences of families with bereavement support services following a perinatal loss.Aust N Z J Obstet Gynaecol. 2018 Feb;58(1):54-63. doi: 10.1111/ajo.12661. Epub 2017 Jun 28.
26 Dysregulated mitochondrial genes and networks with drug targets in postmortem brain of patients with posttraumatic stress disorder (PTSD) revealed by human mitochondria-focused cDNA microarrays.Int J Biol Sci. 2008 Aug 5;4(4):223-35. doi: 10.7150/ijbs.4.223.
27 Association of Neuropeptide S Receptor 1 and Glutamate Decarboxylase 1 Gene Polymorphisms with Posttraumatic Stress Disorder.Psychiatr Danub. 2019 Jun;31(2):249-255. doi: 10.24869/psyd.2019.249.
28 Neuropeptide Y and cannabinoids interaction in the amygdala after exposure to shock and reminders model of PTSD.Neuropharmacology. 2020 Jan 1;162:107804. doi: 10.1016/j.neuropharm.2019.107804. Epub 2019 Oct 14.
29 Glucocorticoids and Hippocampal Structure and Function in PTSD.Harv Rev Psychiatry. 2018 May/Jun;26(3):142-157. doi: 10.1097/HRP.0000000000000188.
30 Buprenorphine for the treatment of posttraumatic stress disorder.Am J Addict. 2019 Feb;28(2):86-91. doi: 10.1111/ajad.12860. Epub 2019 Jan 21.
31 Neuromarkers of Post-Traumatic Stress Disorder (PTSD) in a patient after bilateral hand amputation - ERP case study.Ann Agric Environ Med. 2017 Jun 8;24(2):265-270. doi: 10.26444/aaem/74597. Epub 2017 Jun 8.
32 Variation in SLC1A1 is related to combat-related posttraumatic stress disorder.J Anxiety Disord. 2014 Dec;28(8):902-7. doi: 10.1016/j.janxdis.2014.09.013. Epub 2014 Oct 5.
33 Relationships between GAT1 and PTSD, Depression, and Substance Use Disorder.Brain Sci. 2017 Jan 5;7(1):6. doi: 10.3390/brainsci7010006.
34 Sex dependent influence of a functional polymorphism in steroid 5--reductase type 2 (SRD5A2) on post-traumatic stress symptoms.Am J Med Genet B Neuropsychiatr Genet. 2013 Apr;162B(3):283-292. doi: 10.1002/ajmg.b.32147. Epub 2013 Mar 15.
35 Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning.Biol Psychiatry. 2018 Feb 1;83(3):273-283. doi: 10.1016/j.biopsych.2017.08.012. Epub 2017 Aug 26.
36 Association of COMT and TPH-2 genes with DSM-5 based PTSD symptoms.J Affect Disord. 2015 Feb 1;172:472-8. doi: 10.1016/j.jad.2014.10.034. Epub 2014 Oct 22.
37 Association of TPH1, TPH2, and 5HTTLPR with PTSD and depressive symptoms.J Affect Disord. 2012 Nov;140(3):244-52. doi: 10.1016/j.jad.2012.02.015. Epub 2012 Apr 6.
38 COMT Val(158)Met polymorphism is associated with post-traumatic stress disorder and functional outcome following mild traumatic brain injury.J Clin Neurosci. 2017 Jan;35:109-116. doi: 10.1016/j.jocn.2016.09.017. Epub 2016 Oct 18.
39 PACAP increases Arc/Arg 3.1 expression within the extended amygdala after fear conditioning in rats.Neurobiol Learn Mem. 2019 Jan;157:24-34. doi: 10.1016/j.nlm.2018.11.011. Epub 2018 Nov 17.
40 PACAP and PAC1 receptor in brain development and behavior.Neuropeptides. 2013 Dec;47(6):421-30. doi: 10.1016/j.npep.2013.10.005. Epub 2013 Oct 23.
41 ADRA2B deletion variant influences time-dependent effects of pre-learning stress on long-term memory.Neurobiol Learn Mem. 2017 Apr;140:71-81. doi: 10.1016/j.nlm.2017.02.014. Epub 2017 Feb 22.
42 Increased neuronal apoptosis in medial prefrontal cortex is accompanied with changes of Bcl-2 and Bax in a rat model of post-traumatic stress disorder.J Mol Neurosci. 2013 Sep;51(1):127-37. doi: 10.1007/s12031-013-9965-z. Epub 2013 Feb 5.
43 Single Prolonged Stress induces ATF6 alpha-dependent Endoplasmic reticulum stress and the apoptotic process in medial Frontal Cortex neurons.BMC Neurosci. 2014 Oct 21;15:115. doi: 10.1186/s12868-014-0115-5.
44 Genotype-controlled analysis of serum dopamine -hydroxylase activity in civilian post-traumatic stress disorder.Prog Neuropsychopharmacol Biol Psychiatry. 2010 Dec 1;34(8):1396-401. doi: 10.1016/j.pnpbp.2010.07.002. Epub 2010 Aug 22.
45 Role of dopamine D3 receptor in alleviating behavioural deficits in animal models of post-traumatic stress disorder.Prog Neuropsychopharmacol Biol Psychiatry. 2018 Jun 8;84(Pt A):190-200. doi: 10.1016/j.pnpbp.2018.03.001. Epub 2018 Mar 3.
46 The Role of TaqI DRD2 (rs1800497) and DRD4 VNTR Polymorphisms in Posttraumatic Stress Disorder (PTSD).Psychiatr Danub. 2019 Jun;31(2):263-268. doi: 10.24869/psyd.2019.263.
47 Role of apoptosis in the Post-traumatic stress disorder model-single prolonged stressed rats.Psychoneuroendocrinology. 2018 Sep;95:97-105. doi: 10.1016/j.psyneuen.2018.05.015. Epub 2018 May 12.
48 Processing of affective words in adolescent PTSD-Attentional bias toward social threat.Psychophysiology. 2019 Nov;56(11):e13444. doi: 10.1111/psyp.13444. Epub 2019 Jul 25.
49 The Many Faces of FKBP51.Biomolecules. 2019 Jan 21;9(1):35. doi: 10.3390/biom9010035.
50 Panic results in unique molecular and network changes in the amygdala that facilitate fear responses.Mol Psychiatry. 2020 Feb;25(2):442-460. doi: 10.1038/s41380-018-0119-0. Epub 2018 Aug 14.
51 Applying ketamine to alleviate the PTSD-like effects by regulating the HCN1-related BDNF.Prog Neuropsychopharmacol Biol Psychiatry. 2018 Aug 30;86:313-321. doi: 10.1016/j.pnpbp.2018.03.019. Epub 2018 Mar 27.
52 Orexin as a modulator of fear-related behavior: Hypothalamic control of noradrenaline circuit.Brain Res. 2020 Mar 15;1731:146037. doi: 10.1016/j.brainres.2018.11.032. Epub 2018 Nov 24.
53 Serotonin receptors 2A and 1A modulate anxiety-like behavior in post-traumatic stress disordered mice.Am J Transl Res. 2019 Apr 15;11(4):2288-2303. eCollection 2019.
54 Serotonin 2A receptors are a stress response system: implications for post-traumatic stress disorder.Behav Pharmacol. 2019 Apr;30(2 and 3-Spec Issue):151-162. doi: 10.1097/FBP.0000000000000459.
55 Associations between traumatic brain injury from intimate partner violence and future psychosocial health risks in women.Compr Psychiatry. 2019 Jul;92:13-21. doi: 10.1016/j.comppsych.2019.05.001. Epub 2019 May 14.
56 Selective increase in the association of the 2 adrenergic receptor, Arrestin-1 and p53 with Mdm2 in the ventral hippocampus one month after underwater trauma.Behav Brain Res. 2013 Mar 1;240:26-8. doi: 10.1016/j.bbr.2012.11.009. Epub 2012 Nov 20.
57 Assessing the serum concentration levels of NT-4/5, GPX-1, TNF-, and l-arginine as biomediators of depression severity in first depressive episode patients with and without posttraumatic stress disorder.Pharmacol Rep. 2017 Oct;69(5):1049-1058. doi: 10.1016/j.pharep.2017.04.013. Epub 2017 May 1.
58 Enhanced hippocampal BDNF/TrkB signaling in response to fear conditioning in an animal model of posttraumatic stress disorder.J Psychiatr Res. 2011 Apr;45(4):460-8. doi: 10.1016/j.jpsychires.2010.08.009. Epub 2010 Sep 21.
59 Decreased Nociceptin Receptors Are Related to Resilience and Recovery in College Women Who Have Experienced Sexual Violence: Therapeutic Implications for Posttraumatic Stress Disorder.Biol Psychiatry. 2019 Jun 15;85(12):1056-1064. doi: 10.1016/j.biopsych.2019.02.017. Epub 2019 Apr 4.
60 Association between the OXTR rs53576 genotype and latent profiles of post-traumatic stress disorder and depression symptoms in a representative sample of earthquake survivors.Anxiety Stress Coping. 2020 Mar;33(2):140-147. doi: 10.1080/10615806.2019.1695604. Epub 2019 Nov 26.
61 Posttraumatic stress disorder increases the odds of REM sleep behavior disorder and other parasomnias in Veterans with and without comorbid traumatic brain injury.Sleep. 2020 Mar 12;43(3):zsz237. doi: 10.1093/sleep/zsz237.
62 Treatment of OSA with CPAP Is Associated with Improvement in PTSD Symptoms among Veterans.J Clin Sleep Med. 2017 Jan 15;13(1):57-63. doi: 10.5664/jcsm.6388.
63 Genetic Susceptibility to Posttraumatic Stress Disorder: Analyses of the Oxytocin Receptor, Retinoic Acid Receptor-Related Orphan Receptor A and Cannabinoid Receptor 1 Genes.Psychiatr Danub. 2019 Jun;31(2):219-226. doi: 10.24869/psyd.2019.219.
64 Decreased SGK1 Expression and Function Contributes to Behavioral Deficits Induced by Traumatic Stress.PLoS Biol. 2015 Oct 27;13(10):e1002282. doi: 10.1371/journal.pbio.1002282. eCollection 2015 Oct.
65 Berberine alleviates symptoms of anxiety by enhancing dopamine expression in rats with post-traumatic stress disorder.Korean J Physiol Pharmacol. 2018 Mar;22(2):183-192. doi: 10.4196/kjpp.2018.22.2.183. Epub 2018 Feb 23.
66 The relationship between sense of coherence and post-traumatic stress: a meta-analysis.Eur J Psychotraumatol. 2019 Jan 17;10(1):1562839. doi: 10.1080/20008198.2018.1562839. eCollection 2019.
67 Associations between Polymorphisms in the Solute Carrier Family 6 Member 3 and the Myelin Basic Protein Gene and Posttraumatic Stress Disorder.Psychiatr Danub. 2019 Jun;31(2):235-240. doi: 10.24869/psyd.2019.235.
68 l-Theanine inhibits proinflammatory PKC/ERK/ICAM-1/IL-33 signaling, apoptosis, and autophagy formation in substance P-induced hyperactive bladder in rats.Neurourol Urodyn. 2017 Feb;36(2):297-307. doi: 10.1002/nau.22965. Epub 2016 Feb 1.
69 White matter integrity differences associated with post-traumatic stress disorder are not normalized by concurrent marijuana use.Psychiatry Res Neuroimaging. 2020 Jan 30;295:111017. doi: 10.1016/j.pscychresns.2019.111017. Epub 2019 Nov 14.
70 Role of the Allelic Variation in the 5-Hydroxytryptamine Receptor 1A (HTR1A) and the Tryptophan Hydroxylase 2 (TPH2) Genes in the Development of PTSD.Psychiatr Danub. 2019 Jun;31(2):256-262. doi: 10.24869/psyd.2019.256.
71 Ramelteon Improves Post-traumatic Stress Disorder-Like Behaviors Exhibited by Fatty Acid-Binding Protein 3 Null Mice.Mol Neurobiol. 2018 Apr;55(4):3577-3591. doi: 10.1007/s12035-017-0587-2. Epub 2017 May 17.
72 The Utility of the Hopkins Symptom Checklist as a Trans-Diagnostic Screening Instrument for Common Mental Disorders Among Persons Seeking HIV Testing.AIDS Behav. 2020 Feb;24(2):629-636. doi: 10.1007/s10461-019-02524-6.
73 Relationships between cerebrospinal fluid GABAergic neurosteroid levels and symptom severity in men with PTSD.Psychoneuroendocrinology. 2019 Apr;102:95-104. doi: 10.1016/j.psyneuen.2018.11.027. Epub 2018 Nov 22.
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75 PTSD symptoms predict outcome in trauma-informed treatment of intimate partner aggression.J Consult Clin Psychol. 2017 Oct;85(10):966-974. doi: 10.1037/ccp0000228. Epub 2017 Jul 20.
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78 Uncovering precision phenotype-biomarker associations in traumatic brain injury using topological data analysis.PLoS One. 2017 Mar 3;12(3):e0169490. doi: 10.1371/journal.pone.0169490. eCollection 2017.
79 Examining anxiety sensitivity as a mediator of the association between PTSD symptoms and suicide risk among women firefighters.J Anxiety Disord. 2017 Aug;50:94-102. doi: 10.1016/j.janxdis.2017.06.003. Epub 2017 Jun 13.
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81 The Relationship Between Posttraumatic Stress Disorder Symptoms and Posttraumatic Growth Among HIV-Infected Men Who Have Sex With Men in Beijing, China: The Mediating Roles of Coping Strategies.Front Psychol. 2018 Sep 27;9:1787. doi: 10.3389/fpsyg.2018.01787. eCollection 2018.
82 Effects of calcium-dependent molecular chaperones and endoplasmic reticulum in the amygdala in rats under singleprolonged stress.Mol Med Rep. 2018 Jan;17(1):1099-1104. doi: 10.3892/mmr.2017.7976. Epub 2017 Nov 6.
83 Health-economic benefits of treating trauma in psychosis.Eur J Psychotraumatol. 2019 Jan 21;10(1):1565032. doi: 10.1080/20008198.2018.1565032. eCollection 2019.
84 The MCP-4/MCP-1 ratio in plasma is a candidate circadian biomarker for chronic post-traumatic stress disorder.Transl Psychiatry. 2017 Feb 7;7(2):e1025. doi: 10.1038/tp.2016.285.
85 Incentivizing attendance to prolonged exposure for PTSD with opioid use disorder patients: A randomized controlled trial.J Consult Clin Psychol. 2017 Jul;85(7):689-701. doi: 10.1037/ccp0000208. Epub 2017 Apr 17.
86 Concurrent treatment of substance use disorders and PTSD using prolonged exposure: A randomized clinical trial in military veterans.Addict Behav. 2019 Mar;90:369-377. doi: 10.1016/j.addbeh.2018.11.032. Epub 2018 Nov 27.
87 Levels of the potential biomarker p11 in peripheral blood cells distinguish patients with PTSD from those with other major psychiatric disorders.J Psychiatr Res. 2009 Sep;43(13):1078-85. doi: 10.1016/j.jpsychires.2009.03.010. Epub 2009 Apr 19.
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89 Re-traumatization Cycle: Sexual Abuse, Post-Traumatic Stress Disorder and Sexual Risk Behaviors among Club Drug Users.Subst Use Misuse. 2019;54(9):1499-1508. doi: 10.1080/10826084.2019.1589521. Epub 2019 Apr 25.
90 Genomewide DNA methylation analysis in combat veterans reveals a novel locus for PTSD.Acta Psychiatr Scand. 2017 Nov;136(5):493-505. doi: 10.1111/acps.12778. Epub 2017 Aug 9.
91 Management of post-traumatic stress disorder: A protocol for a multiple treatment comparison meta-analysis of randomized controlled trials.Medicine (Baltimore). 2019 Sep;98(39):e17064. doi: 10.1097/MD.0000000000017064.
92 EFFECT OF THE APOE 4 ALLELE AND COMBAT EXPOSURE ON PTSD AMONG IRAQ/AFGHANISTAN-ERA VETERANS.Depress Anxiety. 2015 May;32(5):307-15. doi: 10.1002/da.22348. Epub 2015 Feb 24.
93 Different polysomnographic patterns in military veterans with obstructive sleep apnea in those with and without post-traumatic stress disorder.Sleep Breath. 2018 Mar;22(1):17-22. doi: 10.1007/s11325-017-1596-0. Epub 2018 Jan 4.
94 GABA(A) receptor beta 3 subunit gene and psychiatric morbidity in a post-traumatic stress disorder population.Psychiatry Res. 2001 Nov 1;104(2):109-17. doi: 10.1016/s0165-1781(01)00296-7.
95 Epigenetic meta-analysis across three civilian cohorts identifies NRG1 and HGS as blood-based biomarkers for post-traumatic stress disorder.Epigenomics. 2018 Dec;10(12):1585-1601. doi: 10.2217/epi-2018-0049. Epub 2018 Nov 20.
96 Improving treatment for patients with childhood abuse related posttraumatic stress disorder (IMPACT study): protocol for a multicenter randomized trial comparing prolonged exposure with intensified prolonged exposure and phase-based treatment.BMC Psychiatry. 2018 Dec 12;18(1):385. doi: 10.1186/s12888-018-1967-5.
97 Genomic predictors of combat stress vulnerability and resilience in U.S. Marines: A genome-wide association study across multiple ancestries implicates PRTFDC1 as a potential PTSD gene.Psychoneuroendocrinology. 2015 Jan;51:459-71. doi: 10.1016/j.psyneuen.2014.10.017. Epub 2014 Oct 30.
98 Heroin Abuse Results in Shifted RNA Expression to Neurodegenerative Diseases and Attenuation of TNF Signaling Pathway.Sci Rep. 2018 Jun 18;8(1):9231. doi: 10.1038/s41598-018-27419-9.
99 Gene expression and methylation signatures of MAN2C1 are associated with PTSD.Dis Markers. 2011;30(2-3):111-21. doi: 10.3233/DMA-2011-0750.
100 Criticism by community people and poor workplace communication as risk factors for the mental health of local welfare workers after the Great East Japan Earthquake: A cross-sectional study.PLoS One. 2017 Nov 22;12(11):e0185930. doi: 10.1371/journal.pone.0185930. eCollection 2017.
101 Sports psychiatry: mental health and mental disorders in athletes and exercise treatment of mental disorders.Eur Arch Psychiatry Clin Neurosci. 2019 Aug;269(5):485-498. doi: 10.1007/s00406-018-0891-5. Epub 2018 Mar 21.
102 An Assessment of Long-Term Physical and Emotional Quality of Life of Persons Injured on 9/11/2001.Int J Environ Res Public Health. 2019 Mar 23;16(6):1054. doi: 10.3390/ijerph16061054.
103 Dysfunctional Coping Mechanisms Contribute to Dry Eye Symptoms.J Clin Med. 2019 Jun 24;8(6):901. doi: 10.3390/jcm8060901.
104 Is Use of a Psychological Workbook Associated With Improved Disabilities of the Arm, Shoulder and Hand Scores in Patients With Distal Radius Fracture?.Clin Orthop Relat Res. 2018 Apr;476(4):832-845. doi: 10.1007/s11999.0000000000000095.
105 Involvement of calcineurin/NFATc4 pathway in a single-prolonged stress-based rat model of post-traumatic stress disorder.Mol Biol Rep. 2019 Dec;46(6):6197-6204. doi: 10.1007/s11033-019-05055-4. Epub 2019 Sep 4.
106 Genome-Wide Association Study of Post-Traumatic Stress Disorder in Two High-Risk Populations.Twin Res Hum Genet. 2017 Jun;20(3):197-207. doi: 10.1017/thg.2017.12. Epub 2017 Mar 6.
107 Genetic risk mechanisms of posttraumatic stress disorder in the human brain.J Neurosci Res. 2018 Jan;96(1):21-30. doi: 10.1002/jnr.23957. Epub 2016 Oct 24.
108 Post-traumatic stress disorder (PTSD) related symptoms following an experience of delirium.J Psychosom Res. 2019 Aug;123:109725. doi: 10.1016/j.jpsychores.2019.05.003. Epub 2019 May 24.
109 Screening for posttraumatic stress disorder in young adult refugees from Syria and Iraq.Compr Psychiatry. 2019 Apr;90:73-81. doi: 10.1016/j.comppsych.2018.11.001. Epub 2018 Dec 14.
110 Post-traumatic stress disorder and chronic hyperconnectivity in emotional processing.Neuroimage Clin. 2018 Jul 10;20:197-204. doi: 10.1016/j.nicl.2018.07.007. eCollection 2018.
111 Network models of posttraumatic stress symptoms across trauma types.J Anxiety Disord. 2018 Aug;58:70-77. doi: 10.1016/j.janxdis.2018.07.004. Epub 2018 Jul 21.
112 Change of Rin1 and Stathmin in the Animal Model of Traumatic Stresses.Front Behav Neurosci. 2017 Apr 26;11:62. doi: 10.3389/fnbeh.2017.00062. eCollection 2017.
113 Posttraumatic stress symptom courses in U.S. military veterans: A seven-year, nationally representative, prospective cohort study.J Psychiatr Res. 2019 Dec;119:23-31. doi: 10.1016/j.jpsychires.2019.09.005. Epub 2019 Sep 12.
114 Altered metabotropic glutamate receptor 5 markers in PTSD: In vivo and postmortem evidence.Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):8390-8395. doi: 10.1073/pnas.1701749114. Epub 2017 Jul 17.
115 Psychosocial interventions for post-traumatic stress disorder in refugees and asylum seekers resettled in high-income countries: Systematic review and meta-analysis.PLoS One. 2017 Feb 2;12(2):e0171030. doi: 10.1371/journal.pone.0171030. eCollection 2017.
116 The Effect of Employment Status in Postdisaster Recovery: A Longitudinal Comparative Study Among Employed and Unemployed Affected Residents.J Trauma Stress. 2018 Jun;31(3):460-466. doi: 10.1002/jts.22282.
117 The Temporal Propagation of Intrinsic Brain Activity Associate With the Occurrence of PTSD.Front Psychiatry. 2018 May 25;9:218. doi: 10.3389/fpsyt.2018.00218. eCollection 2018.
118 Genome-wide association study of posttraumatic stress disorder in a cohort of Iraq-Afghanistan era veterans.J Affect Disord. 2015 Sep 15;184:225-34. doi: 10.1016/j.jad.2015.03.049. Epub 2015 Jun 12.
119 Genetic Perturbation of TIA1 Reveals a Physiological Role in Fear Memory.Cell Rep. 2019 Mar 12;26(11):2970-2983.e4. doi: 10.1016/j.celrep.2019.02.048.
120 The anxiolytic-like effects of ginsenoside Rg2 on an animal model of PTSD.Psychiatry Res. 2019 Sep;279:130-137. doi: 10.1016/j.psychres.2018.12.034. Epub 2018 Dec 6.
121 Decreased AGO2 and DCR1 in PBMCs from War Veterans with PTSD leads to diminished miRNA resulting in elevated inflammation.Transl Psychiatry. 2017 Aug 29;7(8):e1222. doi: 10.1038/tp.2017.185.
122 Effectiveness of interpersonal psychotherapy-trauma for depressed women with childhood abuse histories.J Consult Clin Psychol. 2018 Oct;86(10):868-878. doi: 10.1037/ccp0000335.
123 A polymorphism in the dysbindin gene (DTNBP1) associated with multiple psychiatric disorders including schizophrenia.Behav Brain Funct. 2010 Jul 9;6:41. doi: 10.1186/1744-9081-6-41.
124 The ankyrin-3 gene is associated with posttraumatic stress disorder and externalizing comorbidity.Psychoneuroendocrinology. 2013 Oct;38(10):2249-57. doi: 10.1016/j.psyneuen.2013.04.013. Epub 2013 Jun 21.
125 Genome-wide Association Studies of Posttraumatic Stress Disorder in 2 Cohorts of US Army Soldiers.JAMA Psychiatry. 2016 Jul 1;73(7):695-704. doi: 10.1001/jamapsychiatry.2016.0350.
126 The Use of Virtual Reality to Facilitate Mindfulness Skills Training in Dialectical Behavioral Therapy for Spinal Cord Injury: A Case Study.Front Psychol. 2018 Apr 23;9:531. doi: 10.3389/fpsyg.2018.00531. eCollection 2018.
127 Expression of the PPM1F Gene Is Regulated by Stress and Associated With Anxiety and Depression.Biol Psychiatry. 2018 Feb 1;83(3):284-295. doi: 10.1016/j.biopsych.2017.08.013. Epub 2017 Aug 30.
128 Trauma-informed care improves management of paradoxical vocal fold movement patients.Laryngoscope. 2020 Jun;130(6):1508-1513. doi: 10.1002/lary.28279. Epub 2019 Sep 11.
129 The association between inflammatory markers (iNOS, HO-1, IL-33, MIP-1) and depression with and without posttraumatic stress disorder.Pharmacol Rep. 2018 Dec;70(6):1065-1072. doi: 10.1016/j.pharep.2018.06.001. Epub 2018 Jun 5.
130 Mental health effects following the eruption in Eyjafjallajkull volcano in Iceland: A population-based study.Scand J Public Health. 2019 Mar;47(2):251-259. doi: 10.1177/1403494817751327. Epub 2018 Jan 9.
131 Changes in Trauma-Related Emotions Following Treatment With Dialectical Behavior Therapy for Posttraumatic Stress Disorder After Childhood Abuse.J Trauma Stress. 2019 Oct;32(5):764-773. doi: 10.1002/jts.22440. Epub 2019 Sep 2.
132 Neural Mechanism of a Sex-Specific Risk Variant for Posttraumatic Stress Disorder in the Type I Receptor of the Pituitary Adenylate Cyclase Activating Polypeptide.Biol Psychiatry. 2015 Dec 15;78(12):840-7. doi: 10.1016/j.biopsych.2014.12.018. Epub 2015 Jan 9.
133 Elevated systemic expression of ER stress related genes is associated with stress-related mental disorders in the Detroit Neighborhood Health Study.Psychoneuroendocrinology. 2014 May;43:62-70. doi: 10.1016/j.psyneuen.2014.01.013. Epub 2014 Feb 7.
134 P11 (S100A10) as a potential biomarker of psychiatric patients at risk of suicide.J Psychiatr Res. 2011 Apr;45(4):435-41. doi: 10.1016/j.jpsychires.2010.08.012. Epub 2010 Sep 22.
135 Formin 2 links neuropsychiatric phenotypes at young age to an increased risk for dementia.EMBO J. 2017 Oct 2;36(19):2815-2828. doi: 10.15252/embj.201796821. Epub 2017 Aug 2.
136 Screening for posttraumatic stress disorder in ARDS survivors: validation of the Impact of Event Scale-6 (IES-6).Crit Care. 2019 Aug 7;23(1):276. doi: 10.1186/s13054-019-2553-z.
137 Interpreter-mediated psychotherapy with trauma-affected refugees - A retrospective cohort study.Psychiatry Res. 2019 Jan;271:684-692. doi: 10.1016/j.psychres.2018.12.058. Epub 2018 Dec 10.
138 Differential impact of post-deployment stress and PTSD on neural reactivity to emotional stimuli in Iraq and Afghanistan veterans.J Psychiatr Res. 2018 Jan;96:9-14. doi: 10.1016/j.jpsychires.2017.09.019. Epub 2017 Sep 20.
139 In-Home Sleep Recordings in Military Veterans With Posttraumatic Stress Disorder Reveal Less REM and Deep Sleep <1 Hz.Front Hum Neurosci. 2018 May 11;12:196. doi: 10.3389/fnhum.2018.00196. eCollection 2018.
140 Identification of Key Genes and Pathways in Post-traumatic Stress Disorder Using Microarray Analysis.Front Psychol. 2019 Feb 27;10:302. doi: 10.3389/fpsyg.2019.00302. eCollection 2019.
141 Nitric oxide pathway genes (NOS1AP and NOS1) are involved in PTSD severity, depression, anxiety, stress and resilience.Gene. 2017 Aug 20;625:42-48. doi: 10.1016/j.gene.2017.04.048. Epub 2017 Apr 29.
142 Neuropeptide S in the basolateral amygdala mediates an adaptive behavioral stress response in a rat model of posttraumatic stress disorder by increasing the expression of BDNF and the neuropeptide YY1 receptor.Eur Neuropsychopharmacol. 2018 Jan;28(1):159-170. doi: 10.1016/j.euroneuro.2017.11.006. Epub 2017 Nov 20.
143 Ketamine Administration During Hospitalization Is Not Associated With Posttraumatic Stress Disorder Outcomes in Military Combat Casualties: A Matched Cohort Study.Anesth Analg. 2020 Feb;130(2):402-408. doi: 10.1213/ANE.0000000000004327.
144 Hyperbaric oxygen therapy restored traumatic stress-induced dysregulation of fear memory and related neurochemical abnormalities.Behav Brain Res. 2019 Feb 1;359:861-870. doi: 10.1016/j.bbr.2018.07.014. Epub 2018 Jul 26.
145 Resting-state brain fluctuation and functional connectivity dissociate moral injury from posttraumatic stress disorder.Depress Anxiety. 2019 May;36(5):442-452. doi: 10.1002/da.22883. Epub 2019 Jan 28.
146 The PPM1F gene moderates the association between PTSD and cortical thickness.J Affect Disord. 2019 Dec 1;259:201-209. doi: 10.1016/j.jad.2019.08.055. Epub 2019 Aug 19.
147 The role of posttraumatic stress and posttraumatic growth on online information use in breast cancer survivors.Psychooncology. 2018 Aug;27(8):1971-1978. doi: 10.1002/pon.4753. Epub 2018 May 25.
148 REM theta activity predicts re-experiencing symptoms after exposure to a traumatic film.Sleep Med. 2019 Feb;54:142-152. doi: 10.1016/j.sleep.2018.10.030. Epub 2018 Nov 19.
149 Alpha(2)-adrenergic dysregulation in congenic DxH recombinant inbred mice selectively bred for a high fear-sensitized (H-FSS) startle response.Pharmacol Biochem Behav. 2020 Jan;188:172835. doi: 10.1016/j.pbb.2019.172835. Epub 2019 Dec 2.
150 Glucocorticoid-induced leucine zipper "quantifies" stressors and increases male susceptibility to PTSD.Transl Psychiatry. 2019 Jul 25;9(1):178. doi: 10.1038/s41398-019-0509-3.