General Information of Drug (ID: DMYOP45)

Drug Name
Piceatannol Drug Info
Synonyms
piceatannol; 10083-24-6; 3-Hydroxyresveratol; piceatanol; astringinin; 3,5,3',4'-Tetrahydroxystilbene; (E)-4-(3,5-dihydroxystyryl)benzene-1,2-diol; 3,3',4'5-Tetrahydroxystilbene; 4-[(E)-2-(3,5-dihydroxyphenyl)ethenyl]benzene-1,2-diol; 3,3',4,5'-Tetrahydroxystilbene; UNII-6KS3LS0D4F; NSC 365798; NSC-365798; NSC 622471; 6KS3LS0D4F; CHEMBL69863; 3,3',4,5'-Stilbenetetrol; 4-[(E)-2-(3,5-dihydroxyphenyl)vinyl]benzene-1,2-diol; 4339-71-3; CHEBI:28814; C14H12O4; NSC365798; NSC622471; 1,2-Benzenediol, 4-(2-(3,5-dihydroxyphenyl)ethenyl)-
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
667639
ChEBI ID
CHEBI:28814
CAS Number
CAS 10083-24-6
TTD Drug ID
DMYOP45

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [11]
Selenium DM25CGV N. A. N. A. Approved [12]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [14]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [15]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [17]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [18]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [19]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [20]
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Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [23]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [24]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [25]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [26]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [27]
Testosterone DM7HUNW Hot flushes GA30 Approved [28]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [29]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [31]
Prednisone DM2HG4X Acute asthma CA23 Approved [32]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [32]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [33]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [34]
Epinephrine DM3KJBC Acute asthma CA23 Approved [35]
Quercetin DM3NC4M Obesity 5B81 Approved [23]
Fluoxetine DM3PD2C Bipolar depression Approved [36]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [37]
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Drug(s) Affected By Egl nine homolog 1 (EGLN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [9]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [39]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Ethanol DMDRQZU Chronic pain MG30 Approved [44]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [39]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [45]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [46]
Selenium DM25CGV N. A. N. A. Approved [47]
Methotrexate DM2TEOL Anterior urethra cancer Approved [48]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [49]
Epinephrine DM3KJBC Acute asthma CA23 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [52]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [53]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [54]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [55]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [56]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [57]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [60]
Testosterone DM7HUNW Hot flushes GA30 Approved [60]
Pyruvic acid DM7Q41G Malnutrition 5B50-5B71 Approved [61]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [62]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [62]
ABIRATERONE DM8V75C Prostate cancer 2C82.0 Approved [63]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [59]
Testosterone DM7HUNW Hot flushes GA30 Approved [65]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [66]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Ethanol DMDRQZU Chronic pain MG30 Approved [69]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [70]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [71]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [72]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Mitotane DMU1GX0 Adrenocortical carcinoma 2D11.Z Approved [74]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Urethane DM7NSI0 N. A. N. A. Phase 4 [76]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [77]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [78]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [79]
Forskolin DM6ITNG Solid tumour/cancer 2A00-2F9Z Investigative [80]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [58]
Topiramate DM82Z30 Alcohol dependence 6C40.2 Approved [62]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [62]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Metyrapone DMI7FVQ Cushing disease 5A70 Approved [80]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [58]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [81]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [82]
Levetiracetam DMTGDN8 Epilepsy 8A60-8A68 Approved [68]
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Drug(s) Affected By Sulfotransferase 1E1 (SULT1E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [83]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [83]
Methotrexate DM2TEOL Anterior urethra cancer Approved [84]
Estrone DM5T6US Acne vulgaris ED80 Approved [85]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [83]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [85]
Ethanol DMDRQZU Chronic pain MG30 Approved [86]
Folic Acid DMEMBJC Colorectal carcinoma Approved [87]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [88]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [89]
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Drug(s) Affected By Sulfotransferase 2A1 (SULT2A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [92]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [93]
Leflunomide DMR8ONJ Arthritis FA20 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [95]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [96]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [97]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [98]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [99]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [100]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [102]
Ethacrynic acid DM60QMR Edema MG29 Approved [103]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [104]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [105]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [106]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [107]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [108]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [109]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [110]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [113]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [114]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [115]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [116]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [116]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [117]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [118]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [119]
Etidronic acid DM1XHYJ Bone Paget disease Approved [116]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [116]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [116]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [120]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [121]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [122]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [124]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [125]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [126]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [126]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [127]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [128]
Capsaicin DMGMF6V Back pain ME84.Z Approved [129]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [130]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [131]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [132]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [133]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [134]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [135]
Selenium DM25CGV N. A. N. A. Approved [136]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [131]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [137]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [137]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [138]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [139]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [138]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [141]
Testosterone DM7HUNW Hot flushes GA30 Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Ibrutinib DMHZCPO Mantle cell lymphoma 2A85.5 Approved [144]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [145]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [146]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [148]
Gefitinib DM15F0X Colon adenocarcinoma Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [150]
Selenium DM25CGV N. A. N. A. Approved [151]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [152]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [154]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [155]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [156]
Fructose DM43AN2 Vomiting MD90 Approved [157]
Ketoprofen DMRKXPT Bursitis Approved [157]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [159]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [160]
Gefitinib DM15F0X Colon adenocarcinoma Approved [161]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [165]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [166]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [167]
Paclitaxel DMLB81S Breast carcinoma Approved [168]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [169]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [171]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [172]
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Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [173]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [174]
Fructose DM43AN2 Vomiting MD90 Approved [157]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [21]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [175]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [147]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [176]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [178]
Methotrexate DM2TEOL Anterior urethra cancer Approved [179]
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Drug(s) Affected By Insulin receptor (INSR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [181]
Testosterone DM7HUNW Hot flushes GA30 Approved [182]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [95]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [183]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [145]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [184]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [185]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [186]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Desogestrel DM27U4Y Contraception QA21 Approved [187]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [95]
Testosterone enanthate DMB6871 N. A. N. A. Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Folic Acid DMEMBJC Colorectal carcinoma Approved [87]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [191]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [192]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [193]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [194]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [195]
Cepharanthine DM9Y5JB N. A. N. A. Approved [196]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [197]
Clozapine DMFC71L Schizophrenia 6A20 Approved [198]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [199]
Trifluoperazine DMKBYWI Anxiety Approved [200]
Olanzapine DMPFN6Y Bipolar depression Approved [198]
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Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [201]
Gefitinib DM15F0X Colon adenocarcinoma Approved [202]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [203]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [204]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [205]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [206]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [205]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [207]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [208]
Methotrexate DM2TEOL Anterior urethra cancer Approved [209]
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Drug(s) Affected By Ornithine decarboxylase (ODC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [201]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [210]
Methotrexate DM2TEOL Anterior urethra cancer Approved [211]
Quercetin DM3NC4M Obesity 5B81 Approved [212]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [92]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [92]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [213]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [214]
Propranolol DM79NTF Angina pectoris BA40 Approved [215]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [218]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [219]
Leflunomide DMR8ONJ Arthritis FA20 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [73]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [42]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [45]
Indomethacin DMSC4A7 Bursitis Approved [220]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [75]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [221]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [218]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [41]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Clozapine DMFC71L Schizophrenia 6A20 Approved [224]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [225]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [226]
Folic Acid DMEMBJC Colorectal carcinoma Approved [227]
Methotrexate DM2TEOL Anterior urethra cancer Approved [228]
Quercetin DM3NC4M Obesity 5B81 Approved [229]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [230]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [231]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [232]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [233]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [234]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [234]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [157]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [133]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [235]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [236]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [237]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [238]
Methotrexate DM2TEOL Anterior urethra cancer Approved [90]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [239]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [240]
Quercetin DM3NC4M Obesity 5B81 Approved [241]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [242]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [243]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [244]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [167]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [245]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [246]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [247]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [248]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [249]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Biotin--protein ligase (HLCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [251]
Quercetin DM3NC4M Obesity 5B81 Approved [6]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [189]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [251]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [45]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [253]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eotaxin (CCL11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prednisone DM2HG4X Acute asthma CA23 Approved [254]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [255]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [256]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [219]
Ethanol DMDRQZU Chronic pain MG30 Approved [257]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [258]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [259]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Tacrolimus DMZ7XNQ Graft-versus-host disease 4B24 Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-9 (CASP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [262]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [263]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [201]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [264]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [265]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [266]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [204]
Meloxicam DM2AR7L Arthritis FA20 Approved [267]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [268]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [269]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [270]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [271]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [38]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [272]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [213]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [271]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [273]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [43]
Ethanol DMDRQZU Chronic pain MG30 Approved [274]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [275]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sequestosome-1 (SQSTM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [276]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [277]
Gefitinib DM15F0X Colon adenocarcinoma Approved [278]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [64]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [279]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [251]
Methotrexate DM2TEOL Anterior urethra cancer Approved [280]
Quercetin DM3NC4M Obesity 5B81 Approved [91]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [15]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [282]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [283]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [284]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [133]
Gefitinib DM15F0X Colon adenocarcinoma Approved [285]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [286]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [204]
Selenium DM25CGV N. A. N. A. Approved [12]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [268]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Estrogen receptor beta (ESR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [107]
Gefitinib DM15F0X Colon adenocarcinoma Approved [287]
Quercetin DM3NC4M Obesity 5B81 Approved [288]
Estrone DM5T6US Acne vulgaris ED80 Approved [289]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [290]
Testosterone DM7HUNW Hot flushes GA30 Approved [291]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [292]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [293]
Mestranol DMG3F94 Contraception QA21 Approved [294]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [295]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [201]
Quercetin DM3NC4M Obesity 5B81 Approved [296]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [297]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [298]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [48]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [143]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [299]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [300]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [225]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [301]
Selenium DM25CGV N. A. N. A. Approved [12]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [251]
Quercetin DM3NC4M Obesity 5B81 Approved [302]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [303]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [304]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [305]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [306]
Testosterone DM7HUNW Hot flushes GA30 Approved [142]
Olaparib DM8QB1D Ovarian cancer 2C73 Approved [307]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [308]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [308]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [308]
Capsaicin DMGMF6V Back pain ME84.Z Approved [309]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [310]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [311]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [312]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [313]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [314]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [157]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [98]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [315]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [316]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [317]
Estrone DM5T6US Acne vulgaris ED80 Approved [318]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [319]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [320]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [321]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [322]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [323]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Interferon regulatory factor 3 (IRF3) TTYR7OH IRF3_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 2 (HSD3B2) OT02MSKN 3BHS2_HUMAN Gene/Protein Processing [2]
Amyloid-beta precursor protein (APP) OTKFD7R4 A4_HUMAN Protein Interaction/Cellular Processes [3]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Gene/Protein Processing [4]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [5]
Biotin--protein ligase (HLCS) OTPDUX30 BPL1_HUMAN Gene/Protein Processing [6]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [7]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Gene/Protein Processing [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Gene/Protein Processing [8]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Gene/Protein Processing [9]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [10]

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45 Physiological and toxicological transcriptome changes in HepG2 cells exposed to copper. Physiol Genomics. 2009 Aug 7;38(3):386-401.
46 Neuroprotective effects of glucomoringin-isothiocyanate against H(2)O(2)-Induced cytotoxicity in neuroblastoma (SH-SY5Y) cells. Neurotoxicology. 2019 Dec;75:89-104. doi: 10.1016/j.neuro.2019.09.008. Epub 2019 Sep 12.
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48 Antirheumatic drug response signatures in human chondrocytes: potential molecular targets to stimulate cartilage regeneration. Arthritis Res Ther. 2009;11(1):R15.
49 P450 3A-catalyzed O-dealkylation of lapatinib induces mitochondrial stress and activates Nrf2. Chem Res Toxicol. 2016 May 16;29(5):784-96.
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51 Cissus quadrangularis ethanol extract upregulates superoxide dismutase, glutathione peroxidase and endothelial nitric oxide synthase expression in hydrogen peroxide-injured human ECV304 cells. J Ethnopharmacol. 2012 Sep 28;143(2):664-72.
52 Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. Pain. 2007 Mar;128(1-2):136-47.
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66 Effects of 1alpha,25 dihydroxyvitamin D3 and testosterone on miRNA and mRNA expression in LNCaP cells. Mol Cancer. 2011 May 18;10:58.
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69 Autophagy as a compensation mechanism participates in ethanol-induced fetal adrenal dysfunction in female rats. Toxicol Appl Pharmacol. 2018 Apr 15;345:36-47.
70 Intergenerational genetic programming mechanism and sex differences of the adrenal corticosterone synthesis dysfunction in offspring induced by prenatal ethanol exposure. Toxicol Lett. 2021 Oct 15;351:78-88. doi: 10.1016/j.toxlet.2021.08.007. Epub 2021 Aug 25.
71 Androgen receptor modulation following combination exposure to brominated flame-retardants. Sci Rep. 2018 Mar 19;8(1):4843. doi: 10.1038/s41598-018-23181-0.
72 Estrogenic endocrine disruptive components interfere with calcium handling and differentiation of human trophoblast cells. J Cell Biochem. 2003 Jul 1;89(4):755-70.
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