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Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
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Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
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Identification of IRF8 as a potent tumor suppressor in murine acute promyelocytic leukemia.Blood Adv. 2018 Oct 9;2(19):2462-2466. doi: 10.1182/bloodadvances.2018018929.
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The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia.PLoS One. 2011 Jan 20;6(1):e16340. doi: 10.1371/journal.pone.0016340.
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Critical role of retinoid/rexinoid signaling in mediating transformation and therapeutic response of NUP98-RARG leukemia.Leukemia. 2015 May;29(5):1153-62. doi: 10.1038/leu.2014.334. Epub 2014 Dec 16.
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Targeting PKC delta-mediated topoisomerase II beta overexpression subverts the differentiation block in a retinoic acid-resistant APL cell line.Leukemia. 2010 Apr;24(4):729-39. doi: 10.1038/leu.2010.27. Epub 2010 Mar 4.
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The influence of Wilms' tumor 1 gene expression level on prognosis and risk stratification of acute promyelocytic leukemia patients.Int J Lab Hematol. 2020 Feb;42(1):82-87. doi: 10.1111/ijlh.13144. Epub 2019 Dec 12.
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Driving Toward Precision Medicine for Acute Leukemias: Are We There Yet?.Pharmacotherapy. 2017 Sep;37(9):1052-1072. doi: 10.1002/phar.1977. Epub 2017 Jul 31.
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Enhancement of sensitivity by bestatin of acute promyelocytic leukemia NB4 cells to all-trans retinoic acid.Leuk Res. 2002 Dec;26(12):1097-103. doi: 10.1016/s0145-2126(02)00052-8.
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Aquaporin 9, a promising predictor for the cytocidal effects of arsenic trioxide in acute promyelocytic leukemia cell lines and primary blasts.Oncol Rep. 2013 Jun;29(6):2362-8. doi: 10.3892/or.2013.2388. Epub 2013 Apr 5.
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Prognostic significance of CD44v6/v7 in acute promyelocytic leukemia.Asian Pac J Cancer Prev. 2012;13(8):3791-4. doi: 10.7314/apjcp.2012.13.8.3791.
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Personalized medicine and pharmacogenetic biomarkers: progress in molecular oncology testing.Expert Rev Mol Diagn. 2012 Jul;12(6):593-602. doi: 10.1586/erm.12.59.
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beta2 Integrins are characteristically absent in acute promyelocytic leukemia and rapidly upregulated in vivo upon differentiation with all-trans retinoic acid.Leuk Res. 2007 Jan;31(1):49-57. doi: 10.1016/j.leukres.2006.04.012. Epub 2006 Jun 9.
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A rare case of acute promyelocytic leukemia with IRF2BP2-RARA fusion; and literature review.Onco Targets Ther. 2019 Aug 2;12:6157-6163. doi: 10.2147/OTT.S217622. eCollection 2019.
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Apelin?3 promotes cell proliferation in the H9c2 cardiomyoblast cell line by triggering extracellular signalregulated kinase 1/2 and protein kinase B phosphorylation.Mol Med Rep. 2018 Jan;17(1):447-451. doi: 10.3892/mmr.2017.7919. Epub 2017 Oct 27.
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A novel NPM1-RARG-NPM1 chimeric fusion in acute myeloid leukaemia resembling acute promyelocytic leukaemia but resistant to all-trans retinoic acid and arsenic trioxide.Br J Cancer. 2019 May;120(11):1023-1025. doi: 10.1038/s41416-019-0456-z. Epub 2019 Apr 18.
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Avian erythroleukemia: a model for corepressor function in cancer.Oncogene. 2001 May 28;20(24):3100-9. doi: 10.1038/sj.onc.1204335.
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Gain of MYC underlies recurrent trisomy of the MYC chromosome in acute promyelocytic leukemia.J Exp Med. 2010 Nov 22;207(12):2581-94. doi: 10.1084/jem.20091071. Epub 2010 Nov 8.
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Transformation of Ba/F3 cells and Rat-1 cells by ETV6/ARG.Oncogene. 2002 Jun 27;21(28):4374-83. doi: 10.1038/sj.onc.1205544.
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Thematic review series: Adipocyte Biology. Lipodystrophies: windows on adipose biology and metabolism.J Lipid Res. 2007 Jul;48(7):1433-44. doi: 10.1194/jlr.R700004-JLR200. Epub 2007 Mar 20.
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PML/RARA inhibits expression of HSP90 and its target AKT.Br J Haematol. 2019 Mar;184(6):937-948. doi: 10.1111/bjh.15715. Epub 2018 Dec 9.
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The Role of Abnormal Hemostasis and Fibrinolysis in Morbidity and Mortality of Acute Promyelocytic Leukemia.Semin Thromb Hemost. 2019 Sep;45(6):612-621. doi: 10.1055/s-0039-1693478. Epub 2019 Aug 1.
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Leukemia cell lines: in vitro models for the study of acute promyelocytic leukemia.Leuk Res. 1995 Oct;19(10):681-91. doi: 10.1016/0145-2126(95)00036-n.
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Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9.Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6053-8. doi: 10.1073/pnas.092131899. Epub 2002 Apr 23.
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POZ for effect--POZ-ZF transcription factors in cancer and development.Trends Cell Biol. 2006 Nov;16(11):578-87. doi: 10.1016/j.tcb.2006.09.003. Epub 2006 Sep 22.
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Survivin isoform expression in arsenic trioxide-treated acute promyelocytic leukemia cell line and patients: The odd expression pattern of survivin-2.Asia Pac J Clin Oncol. 2017 Apr;13(2):e21-e30. doi: 10.1111/ajco.12589. Epub 2016 Oct 22.
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Arsenic trioxide promotes histone H3 phosphoacetylation at the chromatin of CASPASE-10 in acute promyelocytic leukemia cells. J Biol Chem. 2002 Dec 20;277(51):49504-10. doi: 10.1074/jbc.M207836200. Epub 2002 Oct 17.
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Carbonyl reductase 1 offers a novel therapeutic target to enhance leukemia treatment by arsenic trioxide. Cancer Res. 2012 Aug 15;72(16):4214-24.
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Leukemia translocation protein PLZF inhibits cell growth and expression of cyclin A.Oncogene. 1999 Jan 28;18(4):925-34. doi: 10.1038/sj.onc.1202375.
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SUMO1 negatively regulates the transcriptional activity of EVI1 and significantly increases its co-localization with EVI1 after treatment with arsenic trioxide.Biochim Biophys Acta. 2013 Oct;1833(10):2357-68. doi: 10.1016/j.bbamcr.2013.06.003. Epub 2013 Jun 13.
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The T-lineage-affiliated CD2 gene lies within an open chromatin environment in acute promyelocytic leukemia cells.Cancer Res. 2002 Aug 15;62(16):4730-5.
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The EMA Review of Mylotarg (Gemtuzumab Ozogamicin) for the Treatment of Acute Myeloid Leukemia.Oncologist. 2019 May;24(5):e171-e179. doi: 10.1634/theoncologist.2019-0025. Epub 2019 Mar 21.
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All-trans-retinoic acid induces CD52 expression in acute promyelocytic leukemia.Blood. 2003 Mar 1;101(5):1977-80. doi: 10.1182/blood-2002-05-1426. Epub 2002 Oct 17.
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Down-regulation of cyclin B1 and up-regulation of Wee1 by berberine promotes entry of leukemia cells into the G2/M-phase of the cell cycle.Anticancer Res. 2006 Mar-Apr;26(2A):1097-104.
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Restoration of CCAAT enhancer binding protein P42 induces myeloid differentiation and overcomes all-trans retinoic acid resistance in human acute promyelocytic leukemia NB4-R1 cells.Int J Oncol. 2015 Nov;47(5):1685-95. doi: 10.3892/ijo.2015.3163. Epub 2015 Sep 14.
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Repression of CDKN2C caused by PML/RAR binding promotes the proliferation and differentiation block in acute promyelocytic leukemia.Front Med. 2016 Dec;10(4):420-429. doi: 10.1007/s11684-016-0478-3. Epub 2016 Dec 23.
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Genotypic and clinical heterogeneity within NCCN favorable-risk acute myeloid leukemia.Leuk Res. 2018 Feb;65:67-73. doi: 10.1016/j.leukres.2017.12.012. Epub 2018 Jan 2.
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C/EBP contributes to transcriptional activation of long non-coding RNA NEAT1 during APL cell differentiation.Biochem Biophys Res Commun. 2018 May 5;499(2):99-104. doi: 10.1016/j.bbrc.2017.10.137. Epub 2017 Oct 27.
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Altered myeloid development and acute leukemia in transgenic mice expressing PML-RAR alpha under control of cathepsin G regulatory sequences.Blood. 1997 Jan 15;89(2):376-87.
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Clinical and pathologic features of secondary acute promyelocytic leukemia.Am J Clin Pathol. 2012 Mar;137(3):395-402. doi: 10.1309/AJCPE0MV0YTWLUUE.
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PML-RARalpha initiates leukemia by conferring properties of self-renewal to committed promyelocytic progenitors.Leukemia. 2009 Aug;23(8):1462-71. doi: 10.1038/leu.2009.63. Epub 2009 Mar 26.
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Pharmacogenomic analysis of acute promyelocytic leukemia cells highlights CYP26 cytochrome metabolism in differential all-trans retinoic acid sensitivity. Blood. 2007 May 15;109(10):4450-60.
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Bone marrow miR-10a overexpression is associated with genetic events but not affects clinical outcome in acute myeloid leukemia.Pathol Res Pract. 2018 Jan;214(1):169-173. doi: 10.1016/j.prp.2017.11.019. Epub 2017 Dec 5.
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ASB2 is an Elongin BC-interacting protein that can assemble with Cullin 5 and Rbx1 to reconstitute an E3 ubiquitin ligase complex.J Biol Chem. 2005 Feb 18;280(7):5468-74. doi: 10.1074/jbc.M413040200. Epub 2004 Dec 8.
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PML(NLS) protein: A novel marker for the early diagnosis of acute promyelocytic leukemia.Mol Med Rep. 2017 Oct;16(4):5418-5424. doi: 10.3892/mmr.2017.7272. Epub 2017 Aug 17.
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Molecular profiling of adult acute myeloid and lymphoid leukemia in a major referral center in Lebanon: a 10-year experience report and review of the literature.Mol Biol Rep. 2019 Apr;46(2):2003-2011. doi: 10.1007/s11033-019-04649-2. Epub 2019 Jan 30.
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Eya2, a Target Activated by Plzf, Is Critical for PLZF-RARA-Induced Leukemogenesis.Mol Cell Biol. 2017 Jun 15;37(13):e00585-16. doi: 10.1128/MCB.00585-16. Print 2017 Jul 1.
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Retinoid-induced differentiation of acute promyelocytic leukemia involves PML-RARalpha-mediated increase of type II transglutaminase.Blood. 1996 Mar 1;87(5):1939-50.
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Syncope as Initial Presentation in an Undifferentiated Type Acute Myeloid Leukemia Patient with Acute Intracranial Hemorrhage.Brain Sci. 2019 Aug 20;9(8):207. doi: 10.3390/brainsci9080207.
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E2f1 regulates the induction of promyelocytic leukemia zinc finger transcription in neuronal differentiation of pluripotent P19 embryonal carcinoma cells.Biochem Biophys Res Commun. 2019 May 7;512(3):629-634. doi: 10.1016/j.bbrc.2019.03.058. Epub 2019 Mar 23.
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The triple-negative (CD34-/HLA-DR-/CD11b-) profile rapidly and specifically identifies an acute promyelocytic leukemia.Int J Lab Hematol. 2018 Apr;40(2):144-151. doi: 10.1111/ijlh.12754. Epub 2017 Oct 6.
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Immunophenotype distinction between acute promyelocytic leukaemia and CD15- CD34- HLA-DR- acute myeloid leukaemia with nucleophosmin mutations.Hematol Oncol. 2012 Sep;30(3):109-14. doi: 10.1002/hon.1011. Epub 2011 Aug 3.
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Arsenic trioxide inhibits the Hedgehog pathway which is aberrantly activated in acute promyelocytic leukemia.Acta Haematol. 2013;130(4):260-7. doi: 10.1159/000351603. Epub 2013 Jul 17.
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Regulation of the hematopoietic cell kinase (HCK) by PML/RAR and PU.1 in acute promyelocytic leukemia.Leuk Res. 2012 Feb;36(2):219-23. doi: 10.1016/j.leukres.2011.09.012. Epub 2011 Oct 10.
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Profiling and functional analysis of circular RNAs in acute promyelocytic leukemia and their dynamic regulation during all-trans retinoic acid treatment.Cell Death Dis. 2018 May 29;9(6):651. doi: 10.1038/s41419-018-0699-2.
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HDAC and HMT Inhibitors in Combination with Conventional Therapy: A Novel Treatment Option for Acute Promyelocytic Leukemia.J Oncol. 2019 Jul 18;2019:6179573. doi: 10.1155/2019/6179573. eCollection 2019.
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A high-resolution STS, EST, and gene-based physical map of the hereditary paraganglioma region on chromosome 11q23.Genomics. 1997 Sep 1;44(2):214-21. doi: 10.1006/geno.1997.4880.
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ID1 and ID2 are retinoic acid responsive genes and induce a G0/G1 accumulation in acute promyelocytic leukemia cells.Leukemia. 2005 May;19(5):799-805. doi: 10.1038/sj.leu.2403699.
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Mutations of Epigenetic Modifier Genes as a Poor Prognostic Factor in Acute Promyelocytic Leukemia Under Treatment With All-Trans Retinoic Acid and Arsenic Trioxide.EBioMedicine. 2015 Apr 12;2(6):563-71. doi: 10.1016/j.ebiom.2015.04.006. eCollection 2015 Jun.
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STAT-3-independent production of IL-17 by mouse innate-like T cells controls ocular infection.J Exp Med. 2018 Apr 2;215(4):1079-1090. doi: 10.1084/jem.20170369. Epub 2018 Feb 28.
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MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation.Mucosal Immunol. 2017 Jan;10(1):35-45. doi: 10.1038/mi.2016.30. Epub 2016 Apr 6.
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The CD9(+) CD11b(-) HLA-DR(-) immunophenotype can be used to diagnose acute promyelocytic leukemia.Int J Lab Hematol. 2019 Apr;41(2):168-175. doi: 10.1111/ijlh.12929. Epub 2018 Oct 13.
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The acetyltransferase GCN5 maintains ATRA-resistance in non-APL AML.Leukemia. 2019 Nov;33(11):2628-2639. doi: 10.1038/s41375-019-0581-y. Epub 2019 Oct 1.
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Molecular circuit involving KLK4 integrates androgen and mTOR signaling in prostate cancer.Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):E2572-81. doi: 10.1073/pnas.1304318110. Epub 2013 Jun 24.
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PML-RAR interferes with erythropoiesis by repressing LMO2 in acute promyelocytic leukaemia.J Cell Mol Med. 2018 Dec;22(12):6275-6284. doi: 10.1111/jcmm.13917. Epub 2018 Oct 15.
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MST-312 induces G2/M cell cycle arrest and apoptosis in APL cells through inhibition of telomerase activity and suppression of NF-B pathway.Tumour Biol. 2015 Nov;36(11):8425-37. doi: 10.1007/s13277-015-3575-z. Epub 2015 May 29.
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An analysis of the impact of CD56 expression in de novo acute promyelocytic leukemia patients treated with upfront all-trans retinoic acid and anthracycline-based regimens.Leuk Lymphoma. 2019 Apr;60(4):1030-1035. doi: 10.1080/10428194.2018.1516875. Epub 2018 Oct 15.
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Cloning and characterization of the t(15;17) translocation breakpoint region in acute promyelocytic leukemia.Genes Chromosomes Cancer. 1990 Jul;2(2):79-87. doi: 10.1002/gcc.2870020202.
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Hydroxydibenzoylmethane induces apoptosis through repressing ornithine decarboxylase in human promyelocytic leukemia HL-60 cells.Exp Mol Med. 2011 Apr 30;43(4):189-96. doi: 10.3858/emm.2011.43.4.023.
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A novel PAD4/SOX4/PU.1 signaling pathway is involved in the committed differentiation of acute promyelocytic leukemia cells into granulocytic cells.Oncotarget. 2016 Jan 19;7(3):3144-57. doi: 10.18632/oncotarget.6551.
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The histone demethylase PHF8 governs retinoic acid response in acute promyelocytic leukemia.Cancer Cell. 2013 Mar 18;23(3):376-89. doi: 10.1016/j.ccr.2013.02.014.
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Pim2 cooperates with PML-RARalpha to induce acute myeloid leukemia in a bone marrow transplantation model.Blood. 2010 Jun 3;115(22):4507-16. doi: 10.1182/blood-2009-03-210070. Epub 2010 Mar 9.
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Leukemic transformation by the APL fusion protein PRKAR1A-RAR{alpha} critically depends on recruitment of RXR{alpha}.Blood. 2010 Jan 21;115(3):643-52. doi: 10.1182/blood-2009-07-232652. Epub 2009 Nov 17.
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis.Nat Commun. 2017 Sep 19;8(1):593. doi: 10.1038/s41467-017-00678-2.
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The impact of oral arsenic and all-trans-retinoic acid on coagulopathy in acute promyelocytic leukemia.Leuk Res. 2018 Feb;65:14-19. doi: 10.1016/j.leukres.2017.11.009. Epub 2017 Nov 15.
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Telomerase-negative immortalized human cells contain a novel type of promyelocytic leukemia (PML) body.Cancer Res. 1999 Sep 1;59(17):4175-9.
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Epigenetically induced ectopic expression of UNCX impairs the proliferation and differentiation of myeloid cells.Haematologica. 2017 Jul;102(7):1204-1214. doi: 10.3324/haematol.2016.163022. Epub 2017 Apr 14.
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The human serglycin gene. Nucleotide sequence and methylation pattern in human promyelocytic leukemia HL-60 cells and T-lymphoblast Molt-4 cells.J Biol Chem. 1992 Jul 5;267(19):13558-63.
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Identification of novel recurrent STAT3-RARA fusions in acute promyelocytic leukemia lacking t(15;17)(q22;q12)/PML-RARA.Blood. 2018 Feb 22;131(8):935-939. doi: 10.1182/blood-2017-09-807370. Epub 2017 Dec 13.
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Acute promyelocytic leukemia with a cryptic insertion of RARA into TBL1XR1.Genes Chromosomes Cancer. 2019 Nov;58(11):820-823. doi: 10.1002/gcc.22791. Epub 2019 Aug 10.
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Serum and thyroid tissue level of let-7b and their correlation with TRAb in Graves' disease.J Transl Med. 2018 Jul 5;16(1):188. doi: 10.1186/s12967-018-1565-9.
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Bortezomib Causes ER Stress-related Death of Acute Promyelocytic Leukemia Cells Through Excessive Accumulation of PML-RARA.Anticancer Res. 2015 Jun;35(6):3307-16.
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The deubiquitinating enzyme USP37 regulates the oncogenic fusion protein PLZF/RARA stability.Oncogene. 2013 Oct 24;32(43):5167-75. doi: 10.1038/onc.2012.537. Epub 2012 Dec 3.
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Effect of all-trans retinoic acid and arsenic trioxide on tissue factor expression in acute promyelocytic leukemia cells.Chin Med J (Engl). 2001 Jan;114(1):30-4.
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Influence of AS3MT polymorphisms on arsenic metabolism and liver injury in APL patients treated with arsenic trioxide.Toxicol Appl Pharmacol. 2019 Sep 15;379:114687. doi: 10.1016/j.taap.2019.114687. Epub 2019 Jul 19.
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Specific small nucleolar RNA expression profiles in acute leukemia.Leukemia. 2012 Sep;26(9):2052-60. doi: 10.1038/leu.2012.111. Epub 2012 Apr 23.
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Molecular analysis of Tripterygium hypoglaucum (level) Hutch-induced mutations at the HPRT locus in human promyelocytic leukemia cells by multiplex polymerase chain reaction.Mutagenesis. 2003 Jan;18(1):77-80. doi: 10.1093/mutage/18.1.77.
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Death-associated protein 5 (DAP5/p97/NAT1) contributes to retinoic acid-induced granulocytic differentiation and arsenic trioxide-induced apoptosis in acute promyelocytic leukemia. Apoptosis. 2008 Jul;13(7):915-28. doi: 10.1007/s10495-008-0222-9.
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Per- and polyfluoroalkyl substances impact human spermatogenesis in a stem-cell-derived model.Syst Biol Reprod Med. 2018 Aug;64(4):225-239. doi: 10.1080/19396368.2018.1481465. Epub 2018 Jun 18.
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A case of recurrent pancytopenia in a patient with acute promyelocytic leukemia on maintenance chemotherapy and concomitant methyltetrahydrofolate reductase and thiopurine S-methyltransferase mutation?review of literature.J Oncol Pharm Pract. 2016 Jun;22(3):548-51. doi: 10.1177/1078155215577235. Epub 2015 Mar 18.
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Whole exome sequencing detects CHST3 mutation in patient with acute promyelocytic leukemia: A case report.Medicine (Baltimore). 2018 Sep;97(36):e12214. doi: 10.1097/MD.0000000000012214.
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RARalpha-PLZF overcomes PLZF-mediated repression of CRABPI, contributing to retinoid resistance in t(11;17) acute promyelocytic leukemia.Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18694-9. doi: 10.1073/pnas.0704433104. Epub 2007 Nov 13.
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Human DMTF1 antagonizes DMTF1 regulation of the p14(ARF) tumor suppressor and promotes cellular proliferation.Biochim Biophys Acta. 2015 Sep;1849(9):1198-208. doi: 10.1016/j.bbagrm.2015.07.009. Epub 2015 Jul 15.
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Inhibition of adipose triglyceride lipase (ATGL) by the putative tumor suppressor G0S2 or a small molecule inhibitor attenuates the growth of cancer cells.Oncotarget. 2015 Sep 29;6(29):28282-95. doi: 10.18632/oncotarget.5061.
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Assessment of late cardiomyopathy by magnetic resonance imaging in patients with acute promyelocytic leukaemia treated with all-trans retinoic acid and idarubicin.Ann Hematol. 2017 Jul;96(7):1077-1084. doi: 10.1007/s00277-017-3004-z. Epub 2017 Apr 28.
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SENP3-mediated de-conjugation of SUMO2/3 from promyelocytic leukemia is correlated with accelerated cell proliferation under mild oxidative stress.J Biol Chem. 2010 Apr 23;285(17):12906-15. doi: 10.1074/jbc.M109.071431. Epub 2010 Feb 24.
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The Mutational Landscape of Acute Promyelocytic Leukemia Reveals an Interacting Network of Co-Occurrences and Recurrent Mutations.PLoS One. 2016 Feb 17;11(2):e0148346. doi: 10.1371/journal.pone.0148346. eCollection 2016.
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TRAIL decoy receptors mediate resistance of acute myeloid leukemia cells to TRAIL.Haematologica. 2005 May;90(5):612-24.
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Exploring the pathophysiology behind the more common genetic and acquired lipodystrophies.J Hum Genet. 2014 Jan;59(1):16-23. doi: 10.1038/jhg.2013.107. Epub 2013 Oct 24.
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Successful treatment of acute promyelocytic leukemia with a t(X;17)(p11.4;q21) and BCOR-RARA fusion gene.Cancer Genet. 2015 Apr;208(4):162-3. doi: 10.1016/j.cancergen.2015.01.008. Epub 2015 Feb 2.
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Precise localization of NF1 to 17q11.2 by balanced translocation.Am J Hum Genet. 1989 Jan;44(1):20-4.
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Nucleostemin silencing induces differentiation and potentiates all-trans-retinoic acid effects in human acute promyelocytic leukemia NB4 cells via autophagy.Leuk Res. 2017 Dec;63:15-21. doi: 10.1016/j.leukres.2017.10.007. Epub 2017 Oct 26.
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ITR?84 modulates cell differentiation in human chronic myelogenous leukemia K562 cells.Oncol Rep. 2018 Jan;39(1):383-391. doi: 10.3892/or.2017.6090. Epub 2017 Nov 9.
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Role and Regulation of Myeloid Zinc Finger Protein 1 in Cancer.J Cell Biochem. 2015 Oct;116(10):2146-54. doi: 10.1002/jcb.25203.
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Therapeutic targeting of nuclear receptor corepressor misfolding in acute promyelocytic leukemia cells with genistein.Mol Cancer Ther. 2007 Aug;6(8):2240-8. doi: 10.1158/1535-7163.MCT-06-0705.
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Variant-type PML-RAR(alpha) fusion transcript in acute promyelocytic leukemia: use of a cryptic coding sequence from intron 2 of the RAR(alpha) gene and identification of a new clinical subtype resistant to retinoic acid therapy.Proc Natl Acad Sci U S A. 2002 May 28;99(11):7640-5. doi: 10.1073/pnas.112194799.
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Arkadia (RING Finger Protein 111) Mediates Sumoylation-Dependent Stabilization of Nrf2 Through K48-Linked Ubiquitination.Cell Physiol Biochem. 2018;46(1):418-430. doi: 10.1159/000488475. Epub 2018 Mar 23.
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p15(Ink4b) Loss of Expression by Promoter Hypermethylation Adds to Leukemogenesis and Confers a Poor Prognosis in Acute Promyelocytic Leukemia Patients.Cancer Res Treat. 2017 Jul;49(3):790-797. doi: 10.4143/crt.2016.108. Epub 2016 Dec 5.
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Twist of Fate for Acute Promyelocytic Leukemia: TRIB3-TWIST1 Interaction Promotes Resistance.Clin Cancer Res. 2019 Oct 15;25(20):6018-6020. doi: 10.1158/1078-0432.CCR-19-2140. Epub 2019 Aug 12.
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ACTL6A interacts with p53 in acute promyelocytic leukemia cell lines to affect differentiation via the Sox2/Notch1 signaling pathway.Cell Signal. 2019 Jan;53:390-399. doi: 10.1016/j.cellsig.2018.11.009. Epub 2018 Nov 15.
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Adenylate cyclase 7 regulated by miR-192 promotes ATRA-induced differentiation of acute promyelocytic leukemia cells.Biochem Biophys Res Commun. 2018 Nov 30;506(3):543-547. doi: 10.1016/j.bbrc.2018.10.125. Epub 2018 Oct 23.
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MicroRNA-181a-mediated downregulation of AC9 protein decreases intracellular cAMP level and inhibits ATRA-induced APL cell differentiation.Cell Death Dis. 2014 Apr 10;5(4):e1161. doi: 10.1038/cddis.2014.130.
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Real-Time PCR analysis of af4 and dek genes expression in acute promyelocytic leukemia t (15;17) patients.Exp Mol Med. 2004 Jun 30;36(3):279-82. doi: 10.1038/emm.2004.38.
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AIDA 0493 protocol for newly diagnosed acute promyelocytic leukemia: very long-term results and role of maintenance.Blood. 2011 May 5;117(18):4716-25. doi: 10.1182/blood-2010-08-302950. Epub 2011 Mar 8.
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Autoimmune regulator: from loss of function to autoimmunity.Genes Immun. 2003 Jan;4(1):12-21. doi: 10.1038/sj.gene.6363929.
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