General Information of Disease (ID: DISR1WNP)

Disease Name Cerebral infarction
Synonyms telencephalon brain infarction; infarction, cerebral; cerebral, infarction; cerebral ischemia; cerebral infarction; cerebral infarct; brain infarction of telencephalon; CVA - cerebral infarction
Disease Class 8B11: Cerebral ischaemic stroke
Definition An ischemic condition of the brain, producing a persistent focal neurological deficit in the area of distribution of the cerebral arteries.
Disease Hierarchy
DISPPGYK: Brain infarction
DISR1WNP: Cerebral infarction
ICD Code
ICD-11
ICD-11: 8B11.5Z
ICD-10
ICD-10: I63
Expand ICD-11
'8B11
Expand ICD-10
'I63
Disease Identifiers
MONDO ID
MONDO_0002679
MESH ID
D002544
UMLS CUI
C0007785
MedGen ID
3321
HPO ID
HP:0025722
SNOMED CT ID
432504007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Midismase DMGCRKY Phase 2 NA [1]
SUN-N8075 DMDOSL0 Phase 1 NA [2]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 4 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
ACEA-1011 DMBY7AZ Terminated Small molecular drug [3]
AK-295 DM51NI0 Terminated Small molecular drug [4]
BN50739 DMU1TRQ Terminated Small molecular drug [5]
RP-66055 DM09QLY Terminated Small molecular drug [6]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 2 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
APT-102 DMEEOY8 Investigative NA [7]
TA-381 DMZYR7I Investigative NA [7]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 124 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
APOH TT2OUI9 Limited Biomarker [8]
LIMK1 TTWL9TY Limited Genetic Variation [9]
LPL TTOF3WZ Limited Genetic Variation [10]
PREP TTNGKET Limited Biomarker [11]
SERPINC1 TT4QPUL Limited Altered Expression [12]
ENPP2 TTSCIM2 Disputed Biomarker [13]
NLRX1 TTKT026 Disputed Genetic Variation [14]
F5 TT1O264 moderate Genetic Variation [15]
LGALS2 TTRHK90 moderate Genetic Variation [16]
PDX1 TT8SGZK moderate Genetic Variation [16]
ROCK2 TTGWKQJ moderate Biomarker [17]
SERPINE1 TTTO43N moderate Genetic Variation [18]
ABCA1 TTJW1GN Strong Genetic Variation [19]
ADORA1 TTK25J1 Strong Biomarker [20]
ADORA2B TTNE7KG Strong Biomarker [21]
ADRA2A TTWG9A4 Strong Altered Expression [22]
AIF1 TT12MEP Strong Biomarker [23]
ANGPT1 TTWNQ1T Strong Altered Expression [24]
ANXA1 TTUCK4B Strong Genetic Variation [25]
AOC3 TT7HC21 Strong Biomarker [26]
APEH TTYWEDQ Strong Biomarker [27]
BCL11A TTR61MW Strong Altered Expression [28]
BSG TT5UJWD Strong Biomarker [29]
CASP4 TT6KIOT Strong Biomarker [30]
CASP6 TTKW4ML Strong Biomarker [31]
CBS TTVZJ7G Strong Biomarker [32]
COASY TT4YO0Z Strong Biomarker [33]
CTSG TTQAJF1 Strong Biomarker [34]
CTSS TTUMQVO Strong Altered Expression [35]
CYP11B2 TT9MNE2 Strong Genetic Variation [36]
DLG4 TT9PB26 Strong Biomarker [37]
DPYSL2 TTZCW3T Strong Biomarker [38]
EPHA4 TTG84D3 Strong Altered Expression [39]
EPHX2 TT7WVHI Strong Biomarker [40]
F12 TTRJSMV Strong Genetic Variation [41]
F2R TTL935N Strong Biomarker [42]
F7 TTF0EGX Strong Genetic Variation [43]
FABP1 TTIV96N Strong Genetic Variation [44]
FABP2 TTS4YLO Strong Genetic Variation [45]
GADD45B TTMDW9L Strong Biomarker [46]
GFAP TTI6FFX Strong Altered Expression [47]
GOT1 TTU507L Strong Biomarker [48]
GPER1 TTDSB34 Strong Biomarker [49]
GPR17 TTMPART Strong Biomarker [50]
GRIN2A TTKJEMQ Strong Biomarker [51]
GRIN2C TT1M8OW Strong Biomarker [52]
HMGB1 TTWQYB7 Strong Altered Expression [53]
HSPB3 TTLH8WG Strong Biomarker [54]
ICAM1 TTA1L39 Strong Altered Expression [42]
IL18 TTRICUF Strong Altered Expression [55]
KLK1 TT5T3P6 Strong Altered Expression [56]
KLK8 TTH5MRS Strong Biomarker [34]
LAMP1 TTC214J Strong Altered Expression [57]
LDLR TTH0DUS Strong Genetic Variation [58]
LILRB1 TTC0QRJ Strong Altered Expression [59]
MAG TT9XFON Strong Genetic Variation [60]
MANF TT56RYE Strong Biomarker [61]
MAP3K11 TTETX6Q Strong Biomarker [62]
MAP3K5 TTOQCD8 Strong Biomarker [63]
MAP3K7 TTJQT60 Strong Altered Expression [64]
MAP4K1 TTSHWUP Strong Biomarker [28]
MAPK10 TT056SO Strong Biomarker [62]
MAPK8IP1 TTXKZ8Q Strong Biomarker [62]
MC4R TTD0CIQ Strong Altered Expression [65]
MCOLN1 TT9XBVO Strong Biomarker [66]
MFGE8 TT1GLAJ Strong Biomarker [67]
MSTN TTM8I2X Strong Biomarker [68]
NOS3 TTCM4B3 Strong Genetic Variation [69]
NOX4 TTQRBSJ Strong Altered Expression [70]
NTN1 TT0AH4L Strong Biomarker [71]
OLR1 TTKSND3 Strong Genetic Variation [72]
PCSK1 TTED9LZ Strong Biomarker [73]
PDE4A TTZ97H5 Strong Biomarker [74]
PDE4D TTSKMI8 Strong Biomarker [75]
PDPK1 TTYMGWX Strong Altered Expression [76]
PHB TT6U071 Strong Altered Expression [77]
PLA2G7 TTDNFMT Strong Altered Expression [78]
PLAT TTXAGYU Strong Biomarker [79]
PLAU TTGY7WI Strong Biomarker [79]
PLK2 TT976FS Strong Biomarker [80]
PRKCH TTONI0R Strong Genetic Variation [81]
PTGDR TTNVEIR Strong Biomarker [82]
PTGER1 TTG1QMU Strong Biomarker [83]
PTGER2 TT1ZAVI Strong Biomarker [84]
PTGIS TTLXKZR Strong Genetic Variation [85]
RAB7A TTF6WAQ Strong Biomarker [86]
RBPJ TT72D4Z Strong Genetic Variation [87]
RTN4 TT7GXMU Strong Genetic Variation [88]
RTN4R TTVRZUO Strong Biomarker [89]
S1PR2 TTVSMOH Strong Biomarker [88]
SCARB1 TTRE324 Strong Genetic Variation [90]
SIRT2 TTLKF5M Strong Biomarker [91]
SLC12A5 TTH6UZY Strong Altered Expression [92]
SLC1A2 TT2F078 Strong Biomarker [93]
SLC5A1 TT2UE56 Strong Altered Expression [94]
SLC6A1 TTPRKM0 Strong Biomarker [95]
SLC8A1 TTCF82X Strong Biomarker [96]
STC1 TTDLUER Strong Biomarker [97]
TBXA2R TT2O84V Strong Genetic Variation [98]
THBD TTAPV67 Strong Biomarker [99]
THPO TTCG5PE Strong Biomarker [100]
TNFRSF12A TTKPS7V Strong Biomarker [101]
TNFSF4 TTBW580 Strong Biomarker [102]
TRPC6 TTRBT3W Strong Biomarker [103]
TRPM2 TTEBMN7 Strong Biomarker [104]
TRPM7 TTFPVZO Strong Biomarker [105]
TXN TTZJ5U9 Strong Biomarker [106]
UGCG TTPHEX3 Strong Biomarker [107]
USP14 TTVSYP9 Strong Biomarker [108]
VDR TTK59TV Strong Biomarker [109]
BACE1 TTJUNZF Definitive Altered Expression [110]
CACNA1B TT4FDG6 Definitive Genetic Variation [111]
F2 TT6L509 Definitive Genetic Variation [112]
GP6 TTTJUVZ Definitive Genetic Variation [113]
GRIK2 TT0K5RG Definitive Biomarker [114]
KCNK3 TTGR91N Definitive Biomarker [115]
KCNN4 TT7M9I6 Definitive Genetic Variation [116]
KLK4 TT4319X Definitive Biomarker [117]
LCAT TTGZ91P Definitive Genetic Variation [118]
NPR2 TTNB7IF Definitive Genetic Variation [119]
NPY TT64REZ Definitive Biomarker [120]
PTGIR TTOFYT1 Definitive Genetic Variation [121]
TBXAS1 TTKNWZ4 Definitive Genetic Variation [122]
UTRN TTNO1VA Definitive Biomarker [123]
------------------------------------------------------------------------------------
⏷ Show the Full List of 124 DTT(s)
This Disease Is Related to 8 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCD2 DT4MBHD Strong Biomarker [124]
ATP2B1 DTJWQ1L Strong Genetic Variation [125]
KCNK2 DTENHUP Strong Biomarker [126]
SLC12A2 DTHKL3Q Strong Altered Expression [92]
SLC35A1 DTVZIRG Strong Biomarker [127]
SLC8A2 DTUASRF Strong Altered Expression [128]
SLC8A3 DTYFRQT Strong Altered Expression [128]
SLC9A6 DTN0JXW Definitive Biomarker [129]
------------------------------------------------------------------------------------
⏷ Show the Full List of 8 DTP(s)
This Disease Is Related to 9 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ADH1B DEEN9RD Strong Biomarker [130]
NMNAT1 DE4D159 Strong Biomarker [131]
PER1 DE9HF0I Strong Biomarker [132]
PON2 DEHJU7E Strong Genetic Variation [133]
PON3 DETXQZ1 Strong Genetic Variation [133]
UBASH3B DE10BJ5 Strong Biomarker [134]
CRMP1 DE0EUXB Definitive Biomarker [123]
CYP4A11 DE2XQGW Definitive Genetic Variation [135]
CYP4F2 DE3GT9C Definitive Biomarker [136]
------------------------------------------------------------------------------------
⏷ Show the Full List of 9 DME(s)
This Disease Is Related to 118 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
BRINP3 OT4VFHWN Limited Biomarker [137]
NUCB2 OTHO6JWN Limited Biomarker [138]
GDF1 OTZ1VRBH Disputed Biomarker [139]
PPP1R13L OTNCPLWE Disputed Biomarker [139]
RNH1 OT6EC79B Disputed Biomarker [139]
SHC3 OT305NPA Disputed Biomarker [139]
SMG1 OTTS3SXE Disputed Biomarker [13]
HBA1 OTW2BQF4 moderate Biomarker [140]
SCG2 OTXWUQQL moderate Biomarker [141]
ADAMTS18 OTRMFI04 Strong Biomarker [142]
ADIPOR2 OT2HDTL8 Strong Genetic Variation [143]
ADPRS OTI1KPN6 Strong Biomarker [144]
ALDH7A1 OTV57BZD Strong Genetic Variation [145]
ANXA6 OT9KIQ0Y Strong Biomarker [134]
AQP4 OTA9MYD5 Strong Biomarker [146]
ATG13 OTYMHNEJ Strong Biomarker [147]
BRAP OTB7BAFQ Strong Biomarker [148]
BTBD8 OT3A3RD7 Strong Biomarker [149]
CALB1 OTM7IXDG Strong Biomarker [150]
CAV2 OT1FGRQX Strong Altered Expression [151]
CBX5 OT8VYY84 Strong Biomarker [152]
CDNF OT1TP2T8 Strong Altered Expression [153]
CKLF OTHLPHA0 Strong Biomarker [154]
CLDN5 OTUX60YO Strong Biomarker [155]
CLDND1 OTGECYGG Strong Altered Expression [156]
COL4A2 OTJK1LKN Strong Genetic Variation [157]
DIO2 OTGPNSLH Strong Biomarker [158]
DNM1L OTXK1Q1G Strong Biomarker [123]
DUOX1 OTQ2AEW0 Strong Altered Expression [159]
EDIL3 OTDVVNS0 Strong Altered Expression [160]
EEF1A1 OT00THXS Strong Altered Expression [17]
EMD OTR8ZANE Strong Biomarker [161]
FCN1 OTK6ZHXH Strong Biomarker [162]
FGB OT6RKLI9 Strong Genetic Variation [163]
FOXF2 OTV20NGX Strong Biomarker [164]
GABPA OT9YB2SA Strong Altered Expression [165]
GAL3ST1 OTSFFZRD Strong Biomarker [127]
GDF11 OTOSNMND Strong Biomarker [166]
HAP1 OT6SG0JQ Strong Biomarker [167]
HOXC13 OT52AVNA Strong Biomarker [168]
HPX OT14T7Q1 Strong Biomarker [169]
HRG OTPLUFOG Strong Genetic Variation [41]
HSPA4 OT5HR0AR Strong Biomarker [170]
HSPB2 OTS01646 Strong Biomarker [54]
IMMP2L OT9WGAFD Strong Biomarker [171]
IMPA1 OTBUVW1Z Strong Biomarker [148]
KCND2 OTIFUVV7 Strong Biomarker [172]
KCNIP3 OTCQPEM4 Strong Biomarker [172]
LMTK2 OT93MVIC Strong Biomarker [173]
MAP2 OT6UYT3X Strong Biomarker [174]
MAP2K3 OTI2OREX Strong Biomarker [175]
MRS2 OTICD11V Strong Biomarker [176]
NCS1 OT6JHAWM Strong Biomarker [177]
NDRG3 OTJTJCHD Strong Biomarker [178]
NEUROG2 OTAEMIGT Strong Biomarker [179]
NGB OTW0SIUY Strong Biomarker [180]
NLN OTFRITPU Strong Biomarker [181]
NOX5 OTHTH59G Strong Altered Expression [182]
NPAS4 OTA3HH6W Strong Altered Expression [183]
NRDC OTWBBCXO Strong Altered Expression [184]
NUBP1 OTE8RAKZ Strong Biomarker [33]
OLIG1 OTIMFI31 Strong Altered Expression [185]
OPN4 OT1LZ7TS Strong Biomarker [181]
OPN5 OTCYGHDA Strong Biomarker [34]
OSBPL9 OTY7IG2V Strong Genetic Variation [186]
OTULIN OTEE02J4 Strong Altered Expression [187]
P3H4 OTZPXYSH Strong Biomarker [188]
PINK1 OT50NR57 Strong Altered Expression [189]
PPIG OTZ8BTTM Strong Genetic Variation [190]
PROZ OTI3TXBE Strong Genetic Variation [191]
PTMA OT2W4T1M Strong Biomarker [192]
RAB7B OT60A0E9 Strong Altered Expression [193]
RAMP2 OTGQXLH5 Strong Biomarker [194]
REST OTLL92LQ Strong Biomarker [195]
RGMB OT2DROYU Strong Altered Expression [196]
RNF146 OTE4CO7E Strong Biomarker [197]
RNF213 OT4OVE9O Strong Altered Expression [198]
SEMA6A OTDQ7QAW Strong Biomarker [199]
SERPINB6 OT7G55IK Strong Biomarker [34]
SERPINF2 OTZGAF8B Strong Genetic Variation [200]
SOD3 OTIOZQAB Strong Biomarker [201]
SPAG11A OTNQ9UB0 Strong Biomarker [84]
SRXN1 OTYDBO4L Strong Biomarker [202]
STK26 OTW4QE0D Strong Biomarker [203]
SUMO2 OT1Y5IKN Strong Biomarker [204]
SUMO3 OTTUJQJ1 Strong Biomarker [204]
TAS2R13 OTSTOX5G Strong Altered Expression [205]
TIGAR OTR7NMRJ Strong Biomarker [206]
TMEM119 OT0HFEIC Strong Altered Expression [207]
TNFAIP6 OT1SLUZH Strong Biomarker [208]
TRAF2 OT1MEZZN Strong Biomarker [209]
TRIB3 OTG5OS7X Strong Altered Expression [205]
TSPAN33 OTH6C0WU Strong Biomarker [210]
ADGRB2 OTOCY7XY Definitive Altered Expression [211]
AKT1S1 OT4JHN4Y Definitive Biomarker [212]
ANGPTL1 OTXIN6V5 Definitive Biomarker [213]
APOBEC1 OTY8QX2R Definitive Altered Expression [214]
CARTPT OTTE4V9S Definitive Biomarker [215]
CEBPZ OT11BATG Definitive Biomarker [216]
DAPK2 OTWODUQG Definitive Biomarker [123]
DENND11 OTC0IJ87 Definitive Biomarker [217]
DENR OTXP9HOY Definitive Biomarker [123]
DSCAM OTL7PRMK Definitive Biomarker [218]
EMP1 OTSZHUHQ Definitive Altered Expression [219]
FGA OTMIHY80 Definitive Biomarker [220]
HCLS1 OTX7WGYN Definitive Altered Expression [221]
HTRA2 OTC7616F Definitive Biomarker [222]
KIDINS220 OTLBH2MA Definitive Altered Expression [223]
NDRG4 OTJBOTD8 Definitive Biomarker [224]
OR2AG1 OTEITRP4 Definitive Biomarker [122]
PLSCR1 OTGY9B5T Definitive Biomarker [225]
PSPN OT54LLZJ Definitive Biomarker [226]
RAMP1 OT7UT2XB Definitive Genetic Variation [227]
RPL13A OTME3VXN Definitive Biomarker [228]
SERPINE2 OTYF5340 Definitive Genetic Variation [229]
SIGLEC7 OTNDLURR Definitive Altered Expression [221]
SMTN OT4R2TYK Definitive Biomarker [230]
ST3GAL4 OTNENJZQ Definitive Biomarker [231]
------------------------------------------------------------------------------------
⏷ Show the Full List of 118 DOT(s)

References

1 ClinicalTrials.gov (NCT00685763) Proton Therapy for Unresectable Cancer (CA) of Pancreas. U.S. National Institutes of Health.
2 Protective effect of SUN N8075, a free radical scavenger, against excessive light-induced retinal damage in mice. Biol Pharm Bull. 2014;37(3):424-30.
3 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007916)
4 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007674)
5 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1851).
6 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003439)
7 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
8 Elevated Levels of Serum 2-Glycoprotein I/Oxidized Low-Density Lipoprotein Complexes Are Associated with Cerebral Infarction in Patients with Type 2 Diabetes Mellitus.Med Sci Monit. 2018 Feb 28;24:1232-1240. doi: 10.12659/msm.907078.
9 Genetic factors for ischemic and hemorrhagic stroke in Japanese individuals.Stroke. 2008 Aug;39(8):2211-8. doi: 10.1161/STROKEAHA.107.507459. Epub 2008 Jun 19.
10 The D9N, N291S, and T495G Polymorphisms of the Lipoprotein Lipase Gene Are Not Associated with Cerebral Infarction.J Stroke Cerebrovasc Dis. 2016 Apr;25(4):985-9. doi: 10.1016/j.jstrokecerebrovasdis.2016.01.017. Epub 2016 Feb 4.
11 A novel IL-1RA-PEP fusion protein with enhanced brain penetration ameliorates cerebral ischemia-reperfusion injury by inhibition of oxidative stress and neuroinflammation.Exp Neurol. 2017 Nov;297:1-13. doi: 10.1016/j.expneurol.2017.06.012. Epub 2017 Jun 8.
12 Correlations of acute myocardial infarction complicated by cerebral infarction with insulin resistance, adiponectin and HMGB1.Eur Rev Med Pharmacol Sci. 2019 May;23(10):4425-4431. doi: 10.26355/eurrev_201905_17951.
13 Atomoxetine Protects Against NMDA Receptor-mediated Hippocampal Neuronal Death Following Transient Global Cerebral Ischemia.Curr Neurovasc Res. 2017;14(2):158-168. doi: 10.2174/1567202614666170328094042.
14 Interactions of TRAF6 and NLRX1 gene polymorphisms with environmental factors on the susceptibility of type 2 diabetes mellitus vascular complications in a southern Han Chinese population.J Diabetes Complications. 2017 Dec;31(12):1652-1657. doi: 10.1016/j.jdiacomp.2017.08.013. Epub 2017 Sep 1.
15 Diffuse cerebral infarct associated with factor V Leiden and prothrombin 20210A mutations in a patient with tetralogy of Fallot.Clin Appl Thromb Hemost. 2009 Dec;15(6):705-7. doi: 10.1177/1076029608319883. Epub 2008 Jun 11.
16 Association of genetic variants with atherothrombotic cerebral infarction in Japanese individuals with metabolic syndrome.Int J Mol Med. 2008 Jun;21(6):801-8.
17 Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.Circ J. 2018 Mar 23;82(4):1195-1204. doi: 10.1253/circj.CJ-17-0732. Epub 2018 Jan 19.
18 Association of Plasminogen Activator Inhibitor 1 (SERPINE1) Polymorphisms and Aneurysmal Subarachnoid Hemorrhage.World Neurosurg. 2017 Sep;105:672-677. doi: 10.1016/j.wneu.2017.05.175. Epub 2017 Jun 6.
19 Tangier disease may cause early onset of atherosclerotic cerebral infarction: A case report.Medicine (Baltimore). 2018 Sep;97(39):e12472. doi: 10.1097/MD.0000000000012472.
20 Moderate cerebral venous congestion induces rapid cerebral protection via adenosine A1 receptor activation.Brain Res. 2006 Nov 29;1122(1):47-55. doi: 10.1016/j.brainres.2006.09.019. Epub 2006 Oct 24.
21 Inhibition of tPA-induced hemorrhagic transformation involves adenosine A2b receptor activation after cerebral ischemia.Neurobiol Dis. 2017 Dec;108:173-182. doi: 10.1016/j.nbd.2017.08.011. Epub 2017 Aug 19.
22 Neuroprotective role of dexmedetomidine pretreatment in cerebral ischemia injury via ADRA2A-mediated phosphorylation of ERK1/2 in adult rats.Exp Ther Med. 2018 Dec;16(6):5201-5209. doi: 10.3892/etm.2018.6878. Epub 2018 Oct 18.
23 Regulation of Microglia and Macrophage Polarization via Apoptosis Signal-Regulating Kinase 1 Silencing after Ischemic/Hypoxic Injury.Front Mol Neurosci. 2017 Aug 14;10:261. doi: 10.3389/fnmol.2017.00261. eCollection 2017.
24 The effect of angiopoietin-1 upregulation on the outcome of acute ischaemic stroke in rodent models: A meta-analysis.J Cereb Blood Flow Metab. 2019 Dec;39(12):2343-2354. doi: 10.1177/0271678X19876876. Epub 2019 Oct 4.
25 A novel cell-penetrating peptide protects against neuron apoptosis after cerebral ischemia by inhibiting the nuclear translocation of annexin A1.Cell Death Differ. 2019 Jan;26(2):260-275. doi: 10.1038/s41418-018-0116-5. Epub 2018 May 16.
26 Simvastatin blocks soluble SSAO/VAP-1 release in experimental models of cerebral ischemia: Possible benefits for stroke-induced inflammation control.Biochim Biophys Acta Mol Basis Dis. 2018 Feb;1864(2):542-553. doi: 10.1016/j.bbadis.2017.11.014. Epub 2017 Nov 22.
27 NLRP3 Inflammasome Is Involved in Q-VD-OPH Induced Necroptosis Following Cerebral Ischemia-Reperfusion Injury.Neurochem Res. 2018 Jun;43(6):1200-1209. doi: 10.1007/s11064-018-2537-4. Epub 2018 May 25.
28 Long noncoding RNA CDKN2B-AS1 interacts with transcription factor BCL11A to regulate progression of cerebral infarction through mediating MAP4K1 transcription.FASEB J. 2019 Jun;33(6):7037-7048. doi: 10.1096/fj.201802252R. Epub 2019 Mar 14.
29 CD147 as a key mediator of the spleen inflammatory response in mice after focal cerebral ischemia.J Neuroinflammation. 2019 Oct 30;16(1):198. doi: 10.1186/s12974-019-1609-y.
30 Caspases and their role in inflammation and ischemic neuronal death. Focus on caspase-12.Apoptosis. 2016 Jul;21(7):763-77. doi: 10.1007/s10495-016-1247-0.
31 Interactome network analysis identifies multiple caspase-6 interactors involved in the pathogenesis of HD.Hum Mol Genet. 2016 Apr 15;25(8):1600-18. doi: 10.1093/hmg/ddw036. Epub 2016 Feb 11.
32 Crystal Structures of Cystathionine -Synthase from Saccharomyces cerevisiae: One Enzymatic Step at a Time.Biochemistry. 2018 Jun 5;57(22):3134-3145. doi: 10.1021/acs.biochem.8b00092. Epub 2018 Apr 13.
33 dl-3-n-butylphthalide promotes neuroplasticity and motor recovery in stroke rats.Behav Brain Res. 2017 Jun 30;329:67-74. doi: 10.1016/j.bbr.2017.04.039. Epub 2017 Apr 22.
34 Targeted disruption of SPI3/Serpinb6 does not result in developmental or growth defects, leukocyte dysfunction, or susceptibility to stroke.Mol Cell Biol. 2004 May;24(9):4075-82. doi: 10.1128/MCB.24.9.4075-4082.2004.
35 Acute phase serum cathepsin S level and cathepsin S/cystatin C ratio are the associated factors with cerebral infarction and their diagnostic value for cerebral infarction.Kaohsiung J Med Sci. 2019 Feb;35(2):95-101. doi: 10.1002/kjm2.12014.
36 Aldosterone synthase gene (CYP11B2) -344C/T polymorphism contributes to the risk of recurrent cerebral ischemia.Genet Test Mol Biomarkers. 2013 Jul;17(7):548-52. doi: 10.1089/gtmb.2013.0026. Epub 2013 May 23.
37 Regional-specific effects of cerebral ischemia/reperfusion and dehydroepiandrosterone on synaptic NMDAR/PSD-95 complex in male Wistar rats.Brain Res. 2018 Jun 1;1688:73-80. doi: 10.1016/j.brainres.2018.03.023. Epub 2018 Mar 22.
38 CRMP2-derived peptide ST2-104 (R9-CBD3) protects SH-SY5Y neuroblastoma cells against A(25-35)-induced neurotoxicity by inhibiting the pCRMP2/NMDAR2B signaling pathway.Chem Biol Interact. 2019 May 25;305:28-39. doi: 10.1016/j.cbi.2019.03.005. Epub 2019 Mar 12.
39 Activation of EphA4 induced by EphrinA1 exacerbates disruption of the blood-brain barrier following cerebral ischemia-reperfusion via the Rho/ROCK signaling pathway.Exp Ther Med. 2018 Sep;16(3):2651-2658. doi: 10.3892/etm.2018.6460. Epub 2018 Jul 17.
40 An epoxide hydrolase inhibitor, 12-(3-adamantan-1-yl-ureido)dodecanoic acid (AUDA), reduces ischemic cerebral infarct size in stroke-prone spontaneously hypertensive rats.J Cardiovasc Pharmacol. 2005 Dec;46(6):842-8. doi: 10.1097/01.fjc.0000189600.74157.6d.
41 Prothrombotic risk factors in childhood stroke and venous thrombosis.Eur J Pediatr. 1999 Dec;158 Suppl 3:S117-21. doi: 10.1007/pl00014333.
42 Dl-3-n-butylphthalide Reduces Neurovascular Inflammation and Ischemic Brain Injury in Mice.Aging Dis. 2019 Oct 1;10(5):964-976. doi: 10.14336/AD.2019.0608. eCollection 2019 Oct.
43 Polymorphisms of the coagulation factor VII gene and its plasma levels in relation to acute cerebral infarction differences in allelic frequencies between Chinese Han and European populations.Chin Med J (Engl). 2004 Jan;117(1):71-4.
44 Fatty Acid Binding Protein-1 (FABP1) and the Human FABP1 T94A Variant: Roles in the Endocannabinoid System and Dyslipidemias.Lipids. 2016 Jun;51(6):655-76. doi: 10.1007/s11745-016-4155-8. Epub 2016 Apr 27.
45 Polymorphism Ala54Thr of fatty acid-binding protein 2 gene is not associated with stroke risk in Han population of Hunan China.Med Sci Monit. 2014 Sep 29;20:1751-7. doi: 10.12659/MSM.892226.
46 ALK5 signaling pathway mediates neurogenesis and functional recovery after cerebral ischemia/reperfusion in rats via Gadd45b.Cell Death Dis. 2019 May 1;10(5):360. doi: 10.1038/s41419-019-1596-z.
47 Limb remote ischemic post-conditioning mitigates brain recovery in a mouse model of ischemic stroke by regulating reactive astrocytic plasticity.Brain Res. 2018 May 1;1686:94-100. doi: 10.1016/j.brainres.2018.02.019. Epub 2018 Feb 17.
48 Human recombinant glutamate oxaloacetate transaminase 1 (GOT1) supplemented with oxaloacetate induces a protective effect after cerebral ischemia.Cell Death Dis. 2014 Jan 9;5(1):e992. doi: 10.1038/cddis.2013.507.
49 Activation of GPR30 with G1 attenuates neuronal apoptosis via src/EGFR/stat3 signaling pathway after subarachnoid hemorrhage in male rats.Exp Neurol. 2019 Oct;320:113008. doi: 10.1016/j.expneurol.2019.113008. Epub 2019 Jul 8.
50 Cangrelor alleviates pulmonary fibrosis by inhibiting GPR17-mediated inflammation in mice.Int Immunopharmacol. 2018 Sep;62:261-269. doi: 10.1016/j.intimp.2018.06.006. Epub 2018 Jul 23.
51 The Role of GluN2A in Cerebral Ischemia: Promoting Neuron Death and Survival in the Early Stage and Thereafter.Mol Neurobiol. 2018 Feb;55(2):1208-1216. doi: 10.1007/s12035-017-0395-8. Epub 2017 Jan 19.
52 Roles of GluN2C in cerebral ischemia: GluN2C expressed in different cell types plays different role in ischemic damage.J Neurosci Res. 2020 Jun;98(6):1188-1197. doi: 10.1002/jnr.24574. Epub 2019 Dec 10.
53 Long noncoding MIAT acting as a ceRNA to sponge microRNA-204-5p to participate in cerebral microvascular endothelial cellinjury after cerebral ischemia through regulating HMGB1.J Cell Physiol. 2020 May;235(5):4571-4586. doi: 10.1002/jcp.29334. Epub 2019 Oct 19.
54 Pentose phosphate pathway activation via HSP27 phosphorylation by ATM kinase: A putative endogenous antioxidant defense mechanism during cerebral ischemia-reperfusion.Brain Res. 2018 May 15;1687:82-94. doi: 10.1016/j.brainres.2018.03.001. Epub 2018 Mar 3.
55 miRNA-20b inhibits cerebral ischemia-induced inflammation through targeting NLRP3.Int J Mol Med. 2019 Mar;43(3):1167-1178. doi: 10.3892/ijmm.2018.4043. Epub 2018 Dec 31.
56 Neuroprotective mechanism of TMP269, a selective class IIA histone deacetylase inhibitor, after cerebral ischemia/reperfusion injury.Neural Regen Res. 2020 Feb;15(2):277-284. doi: 10.4103/1673-5374.265562.
57 Xiao-Xu-Ming Decoction Reduced Mitophagy Activation and Improved Mitochondrial Function in Cerebral Ischemia and Reperfusion Injury.Behav Neurol. 2018 Jun 19;2018:4147502. doi: 10.1155/2018/4147502. eCollection 2018.
58 Relationships of LDLR genetic polymorphisms with cerebral infarction: a meta-analysis.Mol Biol Rep. 2014 Jul;41(7):4425-34. doi: 10.1007/s11033-014-3313-4. Epub 2014 Mar 5.
59 Curcumin Prevents Brain Damage and Cognitive Dysfunction During Ischemic-reperfusion Through the Regulation of miR-7-5p.Curr Neurovasc Res. 2019;16(5):441-454. doi: 10.2174/1567202616666191029113633.
60 Field Validation of the Los Angeles Motor Scale as a Tool for Paramedic Assessment of Stroke Severity.Stroke. 2017 Feb;48(2):298-306. doi: 10.1161/STROKEAHA.116.015247. Epub 2017 Jan 13.
61 Effects of mesencephalic astrocyte-derived neurotrophic factor on cerebral angiogenesis in a rat model of cerebral ischemia.Neurosci Lett. 2020 Jan 10;715:134657. doi: 10.1016/j.neulet.2019.134657. Epub 2019 Nov 27.
62 The potential role of HO-1 in regulating the MLK3-MKK7-JNK3 module scaffolded by JIP1 during cerebral ischemia/reperfusion in rats.Behav Brain Res. 2019 Feb 1;359:528-535. doi: 10.1016/j.bbr.2018.11.003. Epub 2018 Nov 6.
63 Apoptosis Signal-regulating Kinase 1 Silencing on Astroglial Inflammasomes in an Experimental Model of Ischemic Stroke.Neuroscience. 2018 Oct 15;390:218-230. doi: 10.1016/j.neuroscience.2018.08.020. Epub 2018 Aug 31.
64 Acute remote ischemic preconditioning alleviates free radical injury and inflammatory response in cerebral ischemia/reperfusion rats.Exp Ther Med. 2019 Sep;18(3):1953-1960. doi: 10.3892/etm.2019.7797. Epub 2019 Jul 19.
65 Activation of Melanocortin-4 Receptor by a Synthetic Agonist Inhibits Ethanolinduced Neuroinflammation in Rats.Curr Pharm Des. 2019;25(45):4799-4805. doi: 10.2174/1381612825666191216145153.
66 Degradation of TRPML1 in Neurons Reduces Neuron Survival in Transient Global Cerebral Ischemia.Oxid Med Cell Longev. 2018 Dec 18;2018:4612727. doi: 10.1155/2018/4612727. eCollection 2018.
67 Recombinant milk fat globule-EGF factor-8 reduces apoptosis via integrin 3/FAK/PI3K/AKT signaling pathway in rats after traumatic brain injury.Cell Death Dis. 2018 Aug 28;9(9):845. doi: 10.1038/s41419-018-0939-5.
68 Pharmacological inhibition of myostatin improves skeletal muscle mass and function in a mouse model of stroke.Sci Rep. 2017 Oct 25;7(1):14000. doi: 10.1038/s41598-017-13912-0.
69 Association between endothelial nitric oxide synthase gene polymorphisms and risk of ischemic stroke: A meta-analysis.Neurol India. 2017 Jan-Feb;65(1):22-34. doi: 10.4103/0028-3886.198170.
70 NADPH oxidase inhibitor improves outcome of mechanical reperfusion by suppressing hemorrhagic transformation.J Neurointerv Surg. 2017 May;9(5):492-498. doi: 10.1136/neurintsurg-2016-012377. Epub 2016 Apr 13.
71 Exogenous Netrin-1 Inhibits Autophagy of Ischemic Brain Tissues and Hypoxic Neurons via PI3K/mTOR Pathway in Ischemic Stroke.J Stroke Cerebrovasc Dis. 2019 May;28(5):1338-1345. doi: 10.1016/j.jstrokecerebrovasdis.2019.01.032. Epub 2019 Feb 21.
72 Association of the LOX-1 rs1050283 Polymorphism with Risk for Atherosclerotic Cerebral Infarction and its Effect on sLOX-1 and LOX-1 Expression in a Chinese Population.J Atheroscler Thromb. 2017 Jun 1;24(6):572-582. doi: 10.5551/jat.36327. Epub 2016 Nov 12.
73 Necrostatin-1 Improves Long-term Functional Recovery Through Protecting Oligodendrocyte Precursor Cells After Transient Focal Cerebral Ischemia in Mice.Neuroscience. 2018 Feb 10;371:229-241. doi: 10.1016/j.neuroscience.2017.12.007. Epub 2017 Dec 13.
74 Inhibition of PDE4 protects neurons against oxygen-glucose deprivation-induced endoplasmic reticulum stress through activation of the Nrf-2/HO-1 pathway.Redox Biol. 2020 Jan;28:101342. doi: 10.1016/j.redox.2019.101342. Epub 2019 Oct 13.
75 Genotype and haplotype association study of the STRK1 region on 5q12 among Japanese: a case-control study.Stroke. 2006 Jan;37(1):69-76. doi: 10.1161/01.STR.0000194961.17292.33. Epub 2005 Dec 1.
76 Particular phosphorylation of PI3K/Akt on Thr308 via PDK-1 and PTEN mediates melatonin's neuroprotective activity after focal cerebral ischemia in mice.Redox Biol. 2017 Aug;12:657-665. doi: 10.1016/j.redox.2017.04.006. Epub 2017 Apr 5.
77 Neuronal expression of the mitochondrial protein prohibitin confers profound neuroprotection in a mouse model of focal cerebral ischemia.J Cereb Blood Flow Metab. 2018 Jun;38(6):1010-1020. doi: 10.1177/0271678X17720371. Epub 2017 Jul 17.
78 Evaluation of lipoprotein-associated phospholipase A2, serum amyloid A, and fibrinogen as diagnostic biomarkers for patients with acute cerebral infarction.J Clin Lab Anal. 2020 Mar;34(3):e23084. doi: 10.1002/jcla.23084. Epub 2019 Nov 11.
79 The Plasminogen Activation System Promotes Neurorepair in the Ischemic Brain.Curr Drug Targets. 2019;20(9):953-959. doi: 10.2174/1389450120666181211144550.
80 Inhibition of SNK-SPAR signaling pathway promotes the restoration of motor function in a rat model of ischemic stroke.J Cell Biochem. 2018 Jan;119(1):1093-1110. doi: 10.1002/jcb.26278. Epub 2017 Aug 23.
81 Contribution of 1425G/A polymorphism in protein kinase C-Eta (PRKCH) gene and brain white matter lesions to the risk of sudden sensorineural hearing loss in a Japanese nested case-control study.J Neurogenet. 2011 Oct;25(3):82-7. doi: 10.3109/01677063.2011.591462. Epub 2011 Jul 14.
82 GIF-0173 protects against cerebral infarction through DP1 receptor activation.Exp Neurol. 2009 Oct;219(2):481-91. doi: 10.1016/j.expneurol.2009.06.019. Epub 2009 Jul 2.
83 PGE2 EP1 receptor exacerbated neurotoxicity in a mouse model of cerebral ischemia and Alzheimer's disease.Neurobiol Aging. 2012 Sep;33(9):2215-9. doi: 10.1016/j.neurobiolaging.2011.09.017. Epub 2011 Oct 19.
84 PGE(2) signaling via the neuronal EP2 receptor increases injury in a model of cerebral ischemia.Proc Natl Acad Sci U S A. 2019 May 14;116(20):10019-10024. doi: 10.1073/pnas.1818544116. Epub 2019 Apr 29.
85 Splicing mutation of the prostacyclin synthase gene in a family associated with hypertension. Biochem Biophys Res Commun. 2002 Oct 11;297(5):1135-9. doi: 10.1016/s0006-291x(02)02341-0.
86 Autophagosome maturation mediated by Rab7 contributes to neuroprotection of hypoxic preconditioning against global cerebral ischemia in rats.Cell Death Dis. 2017 Jul 20;8(7):e2949. doi: 10.1038/cddis.2017.330.
87 RBPJ polymorphisms associated with cerebral infarction diseases in Chinese Han population: A Clinical Trial/Experimental Study (CONSORT Compliant).Medicine (Baltimore). 2018 Aug;97(31):e11420. doi: 10.1097/MD.0000000000011420.
88 Nogo-A targeted therapy promotes vascular repair and functional recovery following stroke.Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):14270-14279. doi: 10.1073/pnas.1905309116. Epub 2019 Jun 24.
89 Axonal regeneration and functional recovery driven by endogenous Nogo receptor antagonist LOTUS in a rat model of unilateral pyramidotomy.Exp Neurol. 2020 Jan;323:113068. doi: 10.1016/j.expneurol.2019.113068. Epub 2019 Oct 17.
90 Influence of SCARB1 gene SNPs on serum lipid levels and susceptibility to coronary heart disease and cerebral infarction in a Chinese population.Gene. 2017 Aug 30;626:319-325. doi: 10.1016/j.gene.2017.05.020. Epub 2017 May 24.
91 The small RNA microRNA-212 regulates sirtuin 2 expression in a cellular model of oxygen-glucose deprivation.Neuroreport. 2019 Dec 10;30(17):1184-1190. doi: 10.1097/WNR.0000000000001339.
92 Inhibition of Nkcc1 promotes axonal growth and motor recovery in ischemic rats.Neuroscience. 2017 Dec 4;365:83-93. doi: 10.1016/j.neuroscience.2017.09.036. Epub 2017 Sep 28.
93 Dose-dependent target diversion of Danhong injection on the Glu-GLT-1/Gly-GlyR dynamic balance module of cerebral ischemia.Pharmacol Res. 2018 Sep;135:80-88. doi: 10.1016/j.phrs.2018.07.020. Epub 2018 Jul 20.
94 Activation of c-Jun N-terminal kinase and p38 after cerebral ischemia upregulates cerebral sodium-glucose transporter type 1.J Pharmacol Sci. 2018 Dec;138(4):240-246. doi: 10.1016/j.jphs.2017.02.016. Epub 2018 Nov 7.
95 Regulation of GABA transporter mRNA and protein after photothrombotic infarct in rat brain.J Comp Neurol. 2004 Oct 11;478(2):176-88. doi: 10.1002/cne.20282.
96 NCX1 is a new rest target gene: role in cerebral ischemia.Neurobiol Dis. 2013 Feb;50:76-85. doi: 10.1016/j.nbd.2012.10.010. Epub 2012 Oct 13.
97 Stanniocalcin-1 ameliorates cerebral ischemia by decrease oxidative stress and blood brain barrier permeability.Microvasc Res. 2020 Mar;128:103956. doi: 10.1016/j.mvr.2019.103956. Epub 2019 Nov 13.
98 Thromboxane A2 receptor polymorphism in association with cerebral infarction and its regulation on platelet function.Curr Neurovasc Res. 2015;12(1):15-24. doi: 10.2174/1567202612666150102125221.
99 Long-Term Treatment with Thrombomodulin Improves Functional Outcomes after Cerebral Ischemia Even if Administration is Delayed.Thromb Haemost. 2019 Mar;119(3):467-478. doi: 10.1055/s-0038-1677532. Epub 2019 Jan 21.
100 Thrombopoietin could protect cerebral tissue against ischemia-reperfusion injury by suppressing NF-B and MMP-9 expression in rats.Int J Med Sci. 2018 Aug 10;15(12):1341-1348. doi: 10.7150/ijms.27543. eCollection 2018.
101 The interaction between tumor necrosis factor-like weak inducer of apoptosis and its receptor fibroblast growth factor-inducible 14 promotes the recruitment of neutrophils into the ischemic brain.J Cereb Blood Flow Metab. 2010 Jun;30(6):1147-56. doi: 10.1038/jcbfm.2009.280. Epub 2010 Jan 13.
102 Effect of rosuvastatin on OX40L and PPAR- expression in human umbilical vein endothelial cells and atherosclerotic cerebral infarction patients.J Mol Neurosci. 2014 Feb;52(2):261-8. doi: 10.1007/s12031-013-0134-1. Epub 2013 Oct 27.
103 Cerebral ischemia induces TRPC6 via HIF1/ZEB2 axis in the glomerular podocytes and contributes to proteinuria.Sci Rep. 2019 Nov 29;9(1):17897. doi: 10.1038/s41598-019-52872-5.
104 Reversal of Global Ischemia-Induced Cognitive Dysfunction by Delayed Inhibition of TRPM2 Ion Channels.Transl Stroke Res. 2020 Apr;11(2):254-266. doi: 10.1007/s12975-019-00712-z. Epub 2019 Jun 28.
105 Carvacrol after status epilepticus (SE) prevents recurrent SE, early seizures, cell death, and cognitive decline.Epilepsia. 2017 Feb;58(2):263-273. doi: 10.1111/epi.13645. Epub 2017 Jan 13.
106 Nrf2 inhibits NLRP3 inflammasome activation through regulating Trx1/TXNIP complex in cerebral ischemia reperfusion injury.Behav Brain Res. 2018 Jan 15;336:32-39. doi: 10.1016/j.bbr.2017.06.027. Epub 2017 Aug 26.
107 Clinical evaluation of post-operative cerebral infarction in traumatic epidural haematoma.Brain Inj. 2017;31(2):215-220. doi: 10.1080/02699052.2016.1227088. Epub 2017 Jan 5.
108 USP14 inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice.J Neurochem. 2017 Mar;140(5):826-833. doi: 10.1111/jnc.13941. Epub 2017 Jan 26.
109 Genetic variants of vitamin D receptor and susceptibility to ischemic stroke. Biochem Biophys Res Commun. 2015 Jan 9;456(2):631-6. doi: 10.1016/j.bbrc.2014.12.007. Epub 2014 Dec 8.
110 Depletion of GGA3 stabilizes BACE and enhances beta-secretase activity.Neuron. 2007 Jun 7;54(5):721-37. doi: 10.1016/j.neuron.2007.05.012.
111 The haplotype of the CACNA1B gene associated with cerebral infarction in a Japanese population.Hereditas. 2010 Dec;147(6):313-9. doi: 10.1111/j.1601-5223.2009.02115.x.
112 Hereditary thrombophilic factors in stroke due to cerebral infarct.Am J Med Sci. 2009 Jan;337(1):11-3. doi: 10.1097/maj.0b013e3181753b86.
113 The alpha2 Gene alleles of the platelet collagen receptor integrin alpha2 beta1 in Turkish children with cerebral infarct.Thromb Res. 2001 Apr 15;102(2):121-3. doi: 10.1016/s0049-3848(01)00228-6.
114 The role of S-nitrosylation of kainate-type of ionotropic glutamate receptor 2 in epilepsy induced by kainic acid.J Neurochem. 2018 Feb;144(3):255-270. doi: 10.1111/jnc.14266. Epub 2017 Dec 26.
115 From the background to the spotlight: TASK channels in pathological conditions.Brain Pathol. 2010 Nov;20(6):999-1009. doi: 10.1111/j.1750-3639.2010.00407.x.
116 Relationship between haplotypes of KCNN4 gene and susceptibility to human vascular diseases in Japanese.Med Sci Monit. 2009 Aug;15(8):CR389-97.
117 Kallikrein gene transfer induces angiogenesis and further improves regional cerebral blood flow in the early period after cerebral ischemia/reperfusion in rats.CNS Neurosci Ther. 2012 May;18(5):395-9. doi: 10.1111/j.1755-5949.2012.00305.x.
118 [Lecithin-cholesterol acyltransferase gene 608C/T polymorphism associated with atherosclerotic cerebral infarction].Zhonghua Yi Xue Yi Chuan Xue Za Zhi. 2006 Aug;23(4):419-22.
119 An insertion/deletion polymorphism in intron 18 of the type B human natriuretic peptide receptor gene is not associated with cerebral infarction.Hypertens Res. 2000 Mar;23(2):173-6. doi: 10.1291/hypres.23.173.
120 Changes in neuropeptide Y protein expression following photothrombotic brain infarction and epileptogenesis.Brain Res. 2007 Jan 5;1127(1):151-62. doi: 10.1016/j.brainres.2006.09.107. Epub 2006 Nov 22.
121 Effect of single nucleotide polymorphisms of the prostacyclin receptor gene on platelet activation in Japanese healthy subjects and patients with cerebral infarction.J Clin Neurosci. 2013 Jun;20(6):851-6. doi: 10.1016/j.jocn.2012.06.011. Epub 2013 Apr 28.
122 Association of polymorphisms in thromboxane A2 receptor and thromboxane A synthase 1 with cerebral infarction in a Korean population.BMB Rep. 2009 Apr 30;42(4):200-5. doi: 10.5483/bmbrep.2009.42.4.200.
123 Hyperglycemia abolished Drp-1-mediated mitophagy at the early stage of cerebral ischemia.Eur J Pharmacol. 2019 Jan 15;843:34-44. doi: 10.1016/j.ejphar.2018.11.011. Epub 2018 Nov 14.
124 Predictive Value of Head-Neck CTA Combined with ABCD2 Scale Score for Patients with Cerebral Infarction of Vertebrobasilar Transient Ischemic Attack (TIA).Med Sci Monit. 2018 Dec 12;24:9001-9006. doi: 10.12659/MSM.909470.
125 Association between ATP2B1 gene polymorphism and the onset of cerebral infarction.Eur Rev Med Pharmacol Sci. 2019 May;23(10):4348-4353. doi: 10.26355/eurrev_201905_17941.
126 TREK-2 Mediates the Neuroprotective Effect of Isoflurane Preconditioning Against Acute Cerebral Ischemia in the Rat.Rejuvenation Res. 2019 Aug;22(4):325-334. doi: 10.1089/rej.2017.2039. Epub 2018 Dec 28.
127 Overexpression of cortistatin alleviates oxygen/glucose-deprivation-induced ER stress and prompts neural stem cell proliferation via SSTR2.Exp Mol Pathol. 2020 Apr;113:104351. doi: 10.1016/j.yexmp.2019.104351. Epub 2019 Dec 3.
128 Anti-excitotoxic effects of cannabidiol are partly mediated by enhancement of NCX2 and NCX3 expression in animal model of cerebral ischemia.Eur J Pharmacol. 2017 Jan 5;794:270-279. doi: 10.1016/j.ejphar.2016.11.011. Epub 2016 Nov 14.
129 Methicillin-resistant Staphylococcus aureus USA300 clone as a cause of Lemierre's syndrome.J Clin Microbiol. 2011 May;49(5):2063-6. doi: 10.1128/JCM.02507-10. Epub 2011 Mar 23.
130 Alcohol dehydrogenase 2 variant is associated with cerebral infarction and lacunae.Neurology. 2004 Nov 9;63(9):1711-3. doi: 10.1212/01.wnl.0000142971.08275.db.
131 Neuroprotection by nicotinamide mononucleotide adenylyltransferase 1 with involvement of autophagy in an aged rat model of transient cerebral ischemia and reperfusion.Brain Res. 2019 Nov 15;1723:146391. doi: 10.1016/j.brainres.2019.146391. Epub 2019 Aug 14.
132 The Hippocampal Autophagic Machinery is Depressed in the Absence of the Circadian Clock Protein PER1 that may Lead to Vulnerability During Cerebral Ischemia.Curr Neurovasc Res. 2017;14(3):207-214. doi: 10.2174/1567202614666170619083239.
133 PON1 Hypermethylation and PON3 Hypomethylation are Associated with Risk of Cerebral Infarction.Curr Neurovasc Res. 2019;16(2):115-122. doi: 10.2174/1567202616666190412154407.
134 Inhibition of p70 ribosomal S6 kinase 1 (S6K1) by PF-4708671 decreased infarct size in early cerebral ischemia-reperfusion with decreased BBB permeability.Eur J Pharmacol. 2019 Jul 15;855:202-207. doi: 10.1016/j.ejphar.2019.05.010. Epub 2019 May 4.
135 Haplotype-based case study of human CYP4A11 gene and cerebral infarction in Japanese subject.Endocrine. 2008 Apr;33(2):215-22. doi: 10.1007/s12020-008-9078-6. Epub 2008 May 17.
136 A haplotype of the CYP4F2 gene is associated with cerebral infarction in Japanese men.Am J Hypertens. 2008 Nov;21(11):1216-23. doi: 10.1038/ajh.2008.276. Epub 2008 Sep 11.
137 The Expression of microRNA-223 and FAM5C in Cerebral Infarction Patients with Diabetes Mellitus.Cardiovasc Toxicol. 2017 Jan;17(1):42-48. doi: 10.1007/s12012-015-9354-7.
138 Protective effects of Nesfatin-1 peptide on cerebral ischemia reperfusion injury via inhibition of neuronal cell death and enhancement of antioxidant defenses.Metab Brain Dis. 2019 Feb;34(1):79-85. doi: 10.1007/s11011-018-0323-2. Epub 2018 Sep 30.
139 The Shc protein RAI promotes an adaptive cell survival program in hypoxic neuroblastoma cells.J Cell Physiol. 2018 May;233(5):4282-4293. doi: 10.1002/jcp.26247. Epub 2017 Nov 24.
140 Hb Kanagawa [alpha 40(C5)Lys----Met]: a new alpha chain variant with an increased oxygen affinity.Hemoglobin. 1992;16(1-2):1-10. doi: 10.3109/03630269209005670.
141 Secretoneurin: a new player in angiogenesis and chemotaxis linking nerves, blood vessels and the immune system.Curr Protein Pept Sci. 2005 Aug;6(4):373-85. doi: 10.2174/1389203054546334.
142 Adamts18 deficiency increases arterial thrombus formation associated with vascular defects in mice.Biochem Biophys Res Commun. 2018 Feb 19;496(4):1362-1368. doi: 10.1016/j.bbrc.2018.02.032. Epub 2018 Feb 6.
143 Association between adiponectin receptor 2 gene polymorphisms and cerebral infarction.Genet Mol Res. 2014 Sep 26;13(3):7808-14. doi: 10.4238/2014.September.26.19.
144 PARP1 inhibition alleviates injury in ARH3-deficient mice and human cells.JCI Insight. 2019 Feb 21;4(4):e124519. doi: 10.1172/jci.insight.124519. eCollection 2019 Feb 21.
145 A meta-analysis of PDE-gene polymorphism and cerebral infarction risk.Exp Ther Med. 2017 Jun;13(6):2905-2911. doi: 10.3892/etm.2017.4318. Epub 2017 Apr 10.
146 Goreisan Prevents Brain Edema after Cerebral Ischemic Stroke by Inhibiting Aquaporin 4 Upregulation in Mice.J Stroke Cerebrovasc Dis. 2018 Mar;27(3):758-763. doi: 10.1016/j.jstrokecerebrovasdis.2017.10.010. Epub 2017 Nov 16.
147 Rapamycin induces autophagy to alleviate acute kidney injury following cerebral ischemia and reperfusion via the mTORC1/ATG13/ULK1 signaling pathway.Mol Med Rep. 2018 Dec;18(6):5445-5454. doi: 10.3892/mmr.2018.9586. Epub 2018 Oct 24.
148 pSY153-MDR, a p12969-DIM-related mega plasmid carrying bla(IMP-45) and armA, from clinical Pseudomonas putida.Oncotarget. 2017 Jul 22;8(40):68439-68447. doi: 10.18632/oncotarget.19496. eCollection 2017 Sep 15.
149 A Prospective Study of Comparing the Application of Two Generation Scoring Systems in Patients with Acute Cerebral Infarction.Adv Ther. 2019 Nov;36(11):3071-3078. doi: 10.1007/s12325-019-01084-4. Epub 2019 Sep 28.
150 Effect of hyperthermia on calbindin-D 28k immunoreactivity in the hippocampal formation following transient global cerebral ischemia in gerbils.Neural Regen Res. 2017 Sep;12(9):1458-1464. doi: 10.4103/1673-5374.215256.
151 Inhibition of transient receptor potential vanilloid 4 decreases the expressions of caveolin-1 and caveolin-2 after focal cerebral ischemia and reperfusion in rats.Neuropathology. 2018 Apr 17. doi: 10.1111/neup.12469. Online ahead of print.
152 Association of serum levels of antibodies against MMP1, CBX1, and CBX5 with transient ischemic attack and cerebral infarction.Oncotarget. 2017 Dec 31;9(5):5600-5613. doi: 10.18632/oncotarget.23789. eCollection 2018 Jan 19.
153 Cerebral Dopamine Neurotrophic Factor (CDNF) Has Neuroprotective Effects against Cerebral Ischemia That May Occur through the Endoplasmic Reticulum Stress Pathway.Int J Mol Sci. 2018 Jun 29;19(7):1905. doi: 10.3390/ijms19071905.
154 CKLF1 Aggravates Focal Cerebral Ischemia Injury at Early Stage Partly by Modulating Microglia/Macrophage Toward M1 Polarization Through CCR4.Cell Mol Neurobiol. 2019 Jul;39(5):651-669. doi: 10.1007/s10571-019-00669-5. Epub 2019 Apr 13.
155 Absence of MCP-induced Protein 1 Enhances Blood-Brain Barrier Breakdown after Experimental Stroke in Mice.Int J Mol Sci. 2019 Jun 30;20(13):3214. doi: 10.3390/ijms20133214.
156 Levels of tight junction protein CLDND1 are regulated by microRNA-124 in the cerebellum of stroke-prone spontaneously hypertensive rats.Biochem Biophys Res Commun. 2018 Apr 15;498(4):817-823. doi: 10.1016/j.bbrc.2018.03.063. Epub 2018 Mar 13.
157 Different utilization of intensive care services (ICSs) for patients dying of hemorrhagic and ischemic stroke, a hospital-based survey.Medicine (Baltimore). 2018 Feb;97(8):e0017. doi: 10.1097/MD.0000000000010017.
158 Reverse triiodothyronine (rT3) attenuates ischemia-reperfusion injury.Biochem Biophys Res Commun. 2018 Nov 30;506(3):597-603. doi: 10.1016/j.bbrc.2018.10.031. Epub 2018 Oct 23.
159 Mulberrofuran G Protects Ischemic Injury-induced Cell Death via Inhibition of NOX4-mediated ROS Generation and ER Stress.Phytother Res. 2017 Feb;31(2):321-329. doi: 10.1002/ptr.5754. Epub 2016 Dec 2.
160 Del-1 gene transfer induces cerebral angiogenesis in mice.Brain Res. 2008 Jul 11;1219:1-7. doi: 10.1016/j.brainres.2008.05.003. Epub 2008 May 10.
161 Incidence and Risk Factors of the Watershed Shift Phenomenon after Superficial Temporal Artery-Middle Cerebral Artery Anastomosis for Adult Moyamoya Disease.Cerebrovasc Dis. 2019;47(3-4):178-187. doi: 10.1159/000500802. Epub 2019 May 23.
162 Ficolin-1 Levels in Patients Developing Vasospasm and Cerebral Ischemia After Spontaneous Subarachnoid Hemorrhage.Mol Neurobiol. 2017 Oct;54(8):6572-6580. doi: 10.1007/s12035-016-0180-0. Epub 2016 Oct 12.
163 Associations of -Fibrinogen Polymorphisms with the Risk of Ischemic Stroke: A Meta-analysis.J Stroke Cerebrovasc Dis. 2019 Feb;28(2):243-250. doi: 10.1016/j.jstrokecerebrovasdis.2018.09.007. Epub 2018 Nov 29.
164 Identification of additional risk loci for stroke and small vessel disease: a meta-analysis of genome-wide association studies.Lancet Neurol. 2016 Jun;15(7):695-707. doi: 10.1016/S1474-4422(16)00102-2. Epub 2016 Apr 7.
165 Reactive Gliosis Contributes to Nrf2-Dependent Neuroprotection by Pretreatment with Dimethyl Fumarate or Korean Red Ginseng Against Hypoxic-Ischemia: Focus on Hippocampal Injury.Mol Neurobiol. 2020 Jan;57(1):105-117. doi: 10.1007/s12035-019-01760-0. Epub 2019 Sep 7.
166 Growth differentiation factor 11 improves neurobehavioral recovery and stimulates angiogenesis in rats subjected to cerebral ischemia/reperfusion.Brain Res Bull. 2018 May;139:38-47. doi: 10.1016/j.brainresbull.2018.02.011. Epub 2018 Feb 9.
167 Downregulation of GABA(A) Receptor Recycling Mediated by HAP1 Contributes to Neuronal Death in In Vitro Brain Ischemia.Mol Neurobiol. 2017 Jan;54(1):45-57. doi: 10.1007/s12035-015-9661-9. Epub 2016 Jan 5.
168 Vascular endothelial growth factor aggravates cerebral ischemia and reperfusion-induced blood-brain-barrier disruption through regulating LOC102640519/HOXC13/ZO-1 signaling.Exp Cell Res. 2018 Aug 15;369(2):275-283. doi: 10.1016/j.yexcr.2018.05.029. Epub 2018 May 26.
169 Hemopexin promotes angiogenesis via up-regulating HO-1 in rats after cerebral ischemia-reperfusion injury.BMC Anesthesiol. 2018 Jan 3;18(1):2. doi: 10.1186/s12871-017-0466-4.
170 Intranasal Pretreatment with Z-Ligustilide, the Main Volatile Component of Rhizoma Chuanxiong, Confers Prophylaxis against Cerebral Ischemia via Nrf2 and HSP70 Signaling Pathways.J Agric Food Chem. 2017 Mar 1;65(8):1533-1542. doi: 10.1021/acs.jafc.6b04979. Epub 2017 Feb 16.
171 Suppression of Inner Mitochondrial Membrane Peptidase 2-Like (IMMP2L) Gene Exacerbates Hypoxia-Induced Neural Death Under High Glucose Condition.Neurochem Res. 2017 May;42(5):1504-1514. doi: 10.1007/s11064-017-2207-y. Epub 2017 Mar 18.
172 Post-treatment with a Hydrogen Sulfide Donor Limits Neuronal Injury and Modulates Potassium Voltage-gated Channel Subfamily D Member 2 (Kv4.2) and Potassium Channel Interacting Protein 3 (KChIP3) During Transient Global Cerebral Ischemia.Curr Neurovasc Res. 2017;14(4):397-405. doi: 10.2174/1567202614666171108113447.
173 Overexpression of lemur tyrosine kinase-2 protects neurons from oxygen-glucose deprivation/reoxygenation-induced injury through reinforcement of Nrf2 signaling by modulating GSK-3 phosphorylation.Biochem Biophys Res Commun. 2020 Jan 22;521(4):964-970. doi: 10.1016/j.bbrc.2019.11.002. Epub 2019 Nov 10.
174 Neuroprotective effect of Convolvulus pluricaulis Choisy in oxidative stress model of cerebral ischemia reperfusion injury and assessment of MAP2 in rats.J Ethnopharmacol. 2020 Mar 1;249:112393. doi: 10.1016/j.jep.2019.112393. Epub 2019 Nov 16.
175 microRNA-21 Confers Neuroprotection Against Cerebral Ischemia-Reperfusion Injury and Alleviates Blood-Brain Barrier Disruption in Rats via the MAPK Signaling Pathway.J Mol Neurosci. 2018 May;65(1):43-53. doi: 10.1007/s12031-018-1067-5. Epub 2018 Apr 26.
176 Randomization of endovascular treatment with stent-retriever and/or thromboaspiration versus best medical therapy in acute ischemic stroke due to large vessel occlusion trial: Rationale and design.Int J Stroke. 2021 Jan;16(1):100-109. doi: 10.1177/1747493019890700. Epub 2019 Dec 2.
177 Electroacupuncture Alleviates Brain Damage Through Targeting of Neuronal Calcium Sensor 1 by miR-191a-5p After Ischemic Stroke.Rejuvenation Res. 2017 Dec;20(6):492-505. doi: 10.1089/rej.2017.1920. Epub 2017 Jul 17.
178 Let-7f Regulates the Hypoxic Response in Cerebral Ischemia by Targeting NDRG3.Neurochem Res. 2017 Feb;42(2):446-454. doi: 10.1007/s11064-016-2091-x. Epub 2016 Nov 4.
179 TAT-Ngn2 Enhances Cognitive Function Recovery and Regulates Caspase-Dependent and Mitochondrial Apoptotic Pathways After Experimental Stroke.Front Cell Neurosci. 2018 Dec 14;12:475. doi: 10.3389/fncel.2018.00475. eCollection 2018.
180 Neuroglobin mediates neuroprotection of hypoxic postconditioning against transient global cerebral ischemia in rats through preserving the activity of Na(+)/K(+) ATPases.Cell Death Dis. 2018 May 25;9(6):635. doi: 10.1038/s41419-018-0656-0.
181 Protective effects of 8-MOP on blood-brain barrier via the Nrf-2/HO-1 pathway in mice model of cerebral infarction.Eur Rev Med Pharmacol Sci. 2018 Jul;22(13):4278-4287. doi: 10.26355/eurrev_201807_15424.
182 NOX5 as a therapeutic target in cerebral ischemic injury.J Clin Invest. 2019 Mar 18;129(4):1530-1532. doi: 10.1172/JCI127682. eCollection 2019 Mar 18.
183 The Role of the Neuroprotective Factor Npas4 in Cerebral Ischemia.Int J Mol Sci. 2015 Dec 4;16(12):29011-28. doi: 10.3390/ijms161226144.
184 Clinical determination of serum nardilysin levels in predicting 30-day mortality among adults with malignant cerebral infarction.Clin Chim Acta. 2019 Jul;494:8-13. doi: 10.1016/j.cca.2019.03.1608. Epub 2019 Mar 11.
185 Effects of the transcription factor Olig1 on the differentiation and remyelination of oligodendrocyte precursor cells after focal cerebral ischemia in rats.Mol Med Rep. 2019 Nov;20(5):4603-4611. doi: 10.3892/mmr.2019.10713. Epub 2019 Sep 26.
186 Association of oxysterol binding protein-related protein 9 polymorphism with cerebral infarction in Hunan Han population.Ir J Med Sci. 2014 Sep;183(3):439-48. doi: 10.1007/s11845-013-1035-6. Epub 2013 Nov 5.
187 Lentivirus-mediated overexpression of OTULIN ameliorates microglia activation and neuroinflammation by depressing the activation of the NF-B signaling pathway in cerebral ischemia/reperfusion rats.J Neuroinflammation. 2018 Mar 15;15(1):83. doi: 10.1186/s12974-018-1117-5.
188 P3H4 affects renal carcinoma through up-regulating miR-1/133a.Eur Rev Med Pharmacol Sci. 2018 Aug;22(16):5180-5186. doi: 10.26355/eurrev_201808_15714.
189 PINK1 overexpression protects against cerebral ischemia through Parkin regulation.Environ Toxicol. 2020 Feb;35(2):188-193. doi: 10.1002/tox.22855. Epub 2019 Oct 26.
190 Association of platelet response to cilostazol with clinical outcome and CYP genotype in patients with cerebral infarction.Thromb Res. 2018 Dec;172:14-20. doi: 10.1016/j.thromres.2018.10.003. Epub 2018 Oct 10.
191 Variation in coagulation and fibrinolysis genes evaluated for their contribution to cerebrovascular complications in adults with bacterial meningitis in the Netherlands.J Infect. 2018 Jul;77(1):54-59. doi: 10.1016/j.jinf.2018.03.007. Epub 2018 May 7.
192 Prothymosin alpha and its mimetic hexapeptide improve delayed tissue plasminogen activator-induced brain damage following cerebral ischemia.J Neurochem. 2020 Jun;153(6):772-789. doi: 10.1111/jnc.14858. Epub 2019 Oct 10.
193 Rab7b Overexpression-Ameliorated Ischemic Brain Damage Following tMCAO Involves Suppression of TLR4 and NF-B p65.J Mol Neurosci. 2019 Jun;68(2):163-170. doi: 10.1007/s12031-019-01295-y. Epub 2019 Mar 25.
194 Pathophysiological roles of adrenomedullin-RAMP2 system in acute and chronic cerebral ischemia.Peptides. 2014 Dec;62:21-31. doi: 10.1016/j.peptides.2014.08.013. Epub 2014 Sep 22.
195 Inhibition of the Epigenetic Regulator REST Ameliorates Ischemic Brain Injury.Mol Neurobiol. 2019 Apr;56(4):2542-2550. doi: 10.1007/s12035-018-1254-y. Epub 2018 Jul 23.
196 Expression of RGMb in brain tissue of MCAO rats and its relationship with axonal regeneration.J Neurol Sci. 2017 Dec 15;383:79-86. doi: 10.1016/j.jns.2017.10.032. Epub 2017 Oct 24.
197 Neuroprotectin D1 upregulates Iduna expression and provides protection in cellular uncompensated oxidative stress and in experimental ischemic stroke.Cell Death Differ. 2017 Jun;24(6):1091-1099. doi: 10.1038/cdd.2017.55. Epub 2017 Apr 21.
198 Transient Global Cerebral Ischemia Induces RNF213, a Moyamoya Disease Susceptibility Gene, in Vulnerable Neurons of the Rat Hippocampus CA1 Subregion and Ischemic Cortex.J Stroke Cerebrovasc Dis. 2017 Sep;26(9):1904-1911. doi: 10.1016/j.jstrokecerebrovasdis.2017.06.032. Epub 2017 Jul 19.
199 3-N-butylphthalide inhibits neuronal apoptosis in rats with cerebral infarction via targeting P38/MAPK.Eur Rev Med Pharmacol Sci. 2019 Aug;23(3 Suppl):144-152. doi: 10.26355/eurrev_201908_18641.
200 Alpha-2-antiplasmin Arg407Lys polymorphism and cryptogenic ischemic cerebrovascular events: Association with neurological deficit.Neurol Neurochir Pol. 2018 May-Jun;52(3):352-358. doi: 10.1016/j.pjnns.2017.12.009. Epub 2017 Dec 26.
201 Lung-Derived SOD3 Attenuates Neurovascular Injury After Transient Global Cerebral Ischemia.J Am Heart Assoc. 2019 May 7;8(9):e011801. doi: 10.1161/JAHA.118.011801.
202 Neuroprotective effects of sulfiredoxin-1 during cerebral ischemia/reperfusion oxidative stress injury in rats.Brain Res Bull. 2017 Jun;132:99-108. doi: 10.1016/j.brainresbull.2017.05.012. Epub 2017 May 24.
203 MST4 modulates the neuro-inflammatory response by regulating IB signaling pathway and affects the early outcome of experimental ischemic stroke in mice.Brain Res Bull. 2020 Jan;154:43-50. doi: 10.1016/j.brainresbull.2019.10.011. Epub 2019 Nov 10.
204 Hypothermia exerts early neuroprotective effects involving protein conjugation of SUMO?/3 in a rat model of middle cerebral artery occlusion.Mol Med Rep. 2017 Sep;16(3):3217-3223. doi: 10.3892/mmr.2017.6994. Epub 2017 Jul 15.
205 Downregulation of TRB3 protects neurons against apoptosis induced by global cerebral ischemia and reperfusion injury in rats.Neuroscience. 2017 Sep 30;360:118-127. doi: 10.1016/j.neuroscience.2017.07.062. Epub 2017 Aug 4.
206 G6PD plays a neuroprotective role in brain ischemia through promoting pentose phosphate pathway.Free Radic Biol Med. 2017 Nov;112:433-444. doi: 10.1016/j.freeradbiomed.2017.08.011. Epub 2017 Aug 18.
207 TMEM119 marks a subset of microglia in the human brain.Neuropathology. 2016 Feb;36(1):39-49. doi: 10.1111/neup.12235. Epub 2015 Aug 6.
208 Emerging Roles of Tumor Necrosis Factor-Stimulated Gene-6 in the Pathophysiology and Treatment of Atherosclerosis.Int J Mol Sci. 2018 Feb 5;19(2):465. doi: 10.3390/ijms19020465.
209 TRAF2 protects against cerebral ischemia-induced brain injury by suppressing necroptosis.Cell Death Dis. 2019 Apr 15;10(5):328. doi: 10.1038/s41419-019-1558-5.
210 FCPR03, a novel phosphodiesterase 4 inhibitor, alleviates cerebral ischemia/reperfusion injury through activation of the AKT/GSK3/ -catenin signaling pathway.Biochem Pharmacol. 2019 May;163:234-249. doi: 10.1016/j.bcp.2019.02.023. Epub 2019 Feb 21.
211 Brain-specific angiogenesis inhibitor 2 regulates VEGF through GABP that acts as a transcriptional repressor.FEBS Lett. 2006 Jan 23;580(2):669-76. doi: 10.1016/j.febslet.2005.12.086. Epub 2006 Jan 6.
212 Increased expression of a proline-rich Akt substrate (PRAS40) in human copper/zinc-superoxide dismutase transgenic rats protects motor neurons from death after spinal cord injury.J Cereb Blood Flow Metab. 2008 Jan;28(1):44-52. doi: 10.1038/sj.jcbfm.9600501. Epub 2007 Apr 25.
213 Angiopoietin-like protein 1 decreases blood brain barrier damage and edema following focal cerebral ischemia in mice.Neurochem Int. 2008 Feb;52(3):470-7. doi: 10.1016/j.neuint.2007.08.010. Epub 2007 Aug 22.
214 Apobec-1 increases cyclooxygenase-2 and aggravates injury in oxygen-deprived neurogenic cells and middle cerebral artery occlusion rats.Neurochem Res. 2013 Jul;38(7):1434-45. doi: 10.1007/s11064-013-1043-y. Epub 2013 Apr 23.
215 CART protects brain from damage through ERK activation in ischemic stroke.Neuropeptides. 2008 Oct-Dec;42(5-6):653-61. doi: 10.1016/j.npep.2008.05.006. Epub 2008 Jul 21.
216 Regional CBF in apolipoprotein E-deficient and wild type mice during focal cerebral ischemia.Neuroreport. 1998 Aug 3;9(11):2615-20. doi: 10.1097/00001756-199808030-00035.
217 Isolation and characterization of LCHN: a novel factor induced by transient global ischemia in the adult rat hippocampus.J Neurochem. 2007 Apr;101(1):263-73. doi: 10.1111/j.1471-4159.2006.04374.x.
218 Implication of "Down syndrome cell adhesion molecule" in the hippocampal neurogenesis of ischemic monkeys.Hippocampus. 2006;16(11):924-35. doi: 10.1002/hipo.20223.
219 The epithelial membrane protein 1 is a novel tight junction protein of the blood-brain barrier.J Cereb Blood Flow Metab. 2008 Jun;28(6):1249-60. doi: 10.1038/jcbfm.2008.19. Epub 2008 Apr 2.
220 Screening of cerebral infarction-related genetic markers using a Cox regression analysis between onset age and heterozygosity at randomly selected short tandem repeat loci.J Thromb Thrombolysis. 2012 May;33(4):318-21. doi: 10.1007/s11239-012-0724-8.
221 Upregulation of p75 neurotrophin receptor after stroke in mice does not contribute to differential vulnerability of striatal neurons.Exp Neurol. 2001 Jun;169(2):351-63. doi: 10.1006/exnr.2001.7646.
222 Modulation of the Omi/HtrA2 signaling pathway after transient focal cerebral ischemia in mouse brains that overexpress SOD1.Brain Res Mol Brain Res. 2004 Aug 23;127(1-2):89-95. doi: 10.1016/j.molbrainres.2004.05.012.
223 Kidins220/ARMS downregulation by excitotoxic activation of NMDARs reveals its involvement in neuronal survival and death pathways.J Cell Sci. 2009 Oct 1;122(Pt 19):3554-65. doi: 10.1242/jcs.056473.
224 NDRG4 protein-deficient mice exhibit spatial learning deficits and vulnerabilities to cerebral ischemia.J Biol Chem. 2011 Jul 22;286(29):26158-65. doi: 10.1074/jbc.M111.256446. Epub 2011 Jun 2.
225 Spatial resolution of phospholipid scramblase 1 (PLSCR1), caspase-3 activation and DNA-fragmentation in the human hippocampus after cerebral ischemia.Neurochem Int. 2003 Jul;43(1):79-87. doi: 10.1016/s0197-0186(02)00194-8.
226 Effects of cerebral ischemia in mice deficient in Persephin.Proc Natl Acad Sci U S A. 2002 Jul 9;99(14):9521-6. doi: 10.1073/pnas.152535899. Epub 2002 Jul 1.
227 Haplotype-based case-control study of receptor (calcitonin) activity-modifying protein-1 gene in cerebral infarction.J Hum Hypertens. 2010 May;24(5):351-8. doi: 10.1038/jhh.2009.68. Epub 2009 Aug 27.
228 EF1alpha and RPL13a represent normalization genes suitable for RT-qPCR analysis of bone marrow derived mesenchymal stem cells.BMC Mol Biol. 2010 Aug 17;11:61. doi: 10.1186/1471-2199-11-61.
229 Prothrombotic gene polymorphisms and atherothrombotic cerebral infarction.Acta Neurol Scand. 2003 Aug;108(2):109-13. doi: 10.1034/j.1600-0404.2003.00126.x.
230 Association of the smoothelin (SMTN) gene with cerebral infarction in men: a haplotype-based case-control study.Vasc Med. 2012 Oct;17(5):317-25. doi: 10.1177/1358863X12453938.
231 Mild hypothermia alleviates diabetes aggravated cerebral ischemic injury via activating autophagy and inhibiting pyroptosis.Brain Res Bull. 2019 Aug;150:1-12. doi: 10.1016/j.brainresbull.2019.05.003. Epub 2019 May 10.