General Information of Disease (ID: DIS6060I)

Disease Name Pulmonary disease
Synonyms
pulmonary disorder; lung disease; pulmonary disorders; disease or disorder of lung; pulmonary disease; disease of lung; lung disorder; lung disease or disorder; disorder of lung; pulmonary diseases; lung disorders
Disease Class 1B10-1F85: Pulmonary disease
Definition A disease involving the lung.
Disease Hierarchy
DISFWC2Z: Lower respiratory tract disorder
DISWD40R: Disease
DIS6060I: Pulmonary disease
ICD Code
ICD-11
ICD-11: 1B10-1F85
ICD-10
ICD-10: J00-J99
ICD-9
ICD-9: 460-519
Expand ICD-9
4.60E+179
Disease Identifiers
MONDO ID
MONDO_0005275
MESH ID
D008171
UMLS CUI
C0024115
MedGen ID
7399
Orphanet ID
101944
SNOMED CT ID
19829001

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 5 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Aminophylline DML2NIB Approved Small molecular drug [1]
Bovactant DMYN8JE Approved NA [2]
Pirbuterol DMI5678 Approved Small molecular drug [3]
Propyliodone DMNQ76U Approved Small molecular drug [2]
Theophylline DMRJFN9 Approved Small molecular drug [4]
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This Disease is Treated as An Indication in 2 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Amelubant DMUMCB9 Phase 2 Small molecular drug [5]
GS-9411 DM1BMVT Phase 1 NA [6]
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This Disease is Treated as An Indication in 5 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
AGI-350 DMV7AWA Investigative NA [7]
AP-006 DMZX150 Investigative NA [7]
AX-9657 DMKCT0M Investigative Small molecular drug [8]
PSX-4206 DMVJDCM Investigative NA [9]
WilVent DMZ703W Investigative NA [10]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 123 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ADORA1 TTK25J1 Limited Biomarker [11]
ADORA2A TTM2AOE Limited Biomarker [12]
ADORA2B TTNE7KG Limited Altered Expression [13]
APEX1 TTHGL48 Limited Biomarker [14]
BDKRB2 TTGY8IW Limited Biomarker [15]
C3AR1 TTI6B3F Limited Biomarker [16]
C5AR1 TTHXFA1 Limited Biomarker [16]
CAMP TTULOB6 Limited Altered Expression [17]
CCL5 TT9DWLC Limited Biomarker [18]
CEACAM5 TTY6DTE Limited Altered Expression [19]
CEL TTTRNQW Limited Biomarker [20]
CRHR2 TTIY658 Limited Therapeutic [21]
CX3CL1 TT1OFBQ Limited Biomarker [22]
CXCR2 TT30C9G Limited Biomarker [23]
DNASE1 TTYWGOJ Limited Biomarker [24]
ENG TTB30LE Limited Biomarker [25]
GSN TTUH7OM Limited Biomarker [26]
IGF2R TTPNE41 Limited Biomarker [27]
IL13 TT0GVCH Limited Biomarker [28]
IL9 TT0JTFD Limited Altered Expression [29]
INSR TTCBFJO Limited Biomarker [27]
IRF1 TT4TU3L Limited Biomarker [30]
LAIR1 TTSI7A8 Limited Biomarker [31]
MMP8 TTGA1IV Limited Biomarker [32]
MYLK TT18ETS Limited Biomarker [33]
PCSK5 TTPFWHU Limited Biomarker [34]
PDGFA TTSM78N Limited Biomarker [35]
PDGFRA TT8FYO9 Limited Biomarker [35]
PRKDC TTK3PY9 Limited Biomarker [36]
PTH1R TTFPD47 Limited Biomarker [37]
SFTPD TTGLMU7 Limited Biomarker [38]
SLC9A3 TTFZVPO Limited Biomarker [39]
STAT3 TTHJT3X Limited Biomarker [40]
TLR3 TTD24Y0 Limited Biomarker [41]
TRPC6 TTRBT3W Limited Biomarker [42]
TSLP TTHMW3T Limited Biomarker [43]
BPI TTXCSDR Disputed Biomarker [44]
CEACAM6 TTIGH2W Disputed Altered Expression [45]
CXCR1 TTMWT8Z Disputed Genetic Variation [46]
IL1RL1 TT4GZA4 Disputed Biomarker [47]
IL32 TTD4G7L Disputed Biomarker [48]
P2RX1 TTJW7B3 Disputed Biomarker [49]
P2RX3 TT2THBD Disputed Biomarker [49]
ACLY TT0Z6Y2 moderate Biomarker [50]
EREG TTYSB89 moderate Biomarker [51]
FOSL2 TT689IR moderate Biomarker [52]
HDAC8 TTT6LFV moderate Biomarker [53]
IFNAR2 TTMQB37 moderate Genetic Variation [54]
LY96 TT8S9AV moderate Biomarker [55]
NR3C1 TTOZRK6 moderate Biomarker [56]
PTGDR2 TTQDMX5 moderate Biomarker [57]
TLR4 TTISGCA moderate Biomarker [58]
ADA TTLP57V Strong Altered Expression [59]
ADRA2B TTWM4TY Strong Biomarker [60]
ADRB2 TTG8ZWP Strong Biomarker [61]
ADRB3 TTMXGCW Strong Biomarker [62]
AGER TTMO9HF Strong Biomarker [63]
CA12 TTSYM0R Strong Genetic Variation [64]
CARM1 TTIZQFJ Strong Biomarker [65]
CCN2 TTIL516 Strong Biomarker [66]
CCR1 TTC24WT Strong Altered Expression [67]
CD1A TTBGTFN Strong Biomarker [68]
CHIT1 TTDYX6T Strong Genetic Variation [69]
CTH TTLQUZS Strong Biomarker [70]
CTSC TT4H0V2 Strong Biomarker [71]
CTSG TTQAJF1 Strong Biomarker [72]
CTSH TT3G406 Strong Biomarker [73]
CTSS TTUMQVO Strong Altered Expression [74]
CXCL1 TTLK1RW Strong Biomarker [75]
CXCL10 TTQOVYA Strong Biomarker [76]
CXCL2 TTZF0K2 Strong Biomarker [77]
DHPS TTBO2A9 Strong Genetic Variation [78]
EGR1 TTE8LGD Strong Biomarker [79]
F2RL1 TTQR74A Strong Biomarker [80]
FLNA TTSTRZY Strong Genetic Variation [81]
FPR1 TT5Y4EM Strong Biomarker [82]
GLA TTIS03D Strong Biomarker [83]
GREM1 TTOUZN5 Strong Biomarker [51]
HIF1A TTSN6QU Strong Biomarker [84]
HNRNPA2B1 TT8UPW6 Strong Altered Expression [85]
IFNGR2 TT13TL0 Strong Biomarker [86]
IGF1R TTQFBMY Strong Biomarker [87]
ITGAE TTH0Z37 Strong Altered Expression [88]
KIT TTX41N9 Strong Biomarker [89]
LANCL1 TTZW8NS Strong Altered Expression [29]
LCK TT860QF Strong Biomarker [90]
LPAR6 TTZDAGB Strong Biomarker [91]
MBL2 TTMQDZ5 Strong Biomarker [92]
METAP2 TTZL0OI Strong Biomarker [93]
MIF TT6804T Strong Biomarker [94]
MPO TTVCZPI Strong Altered Expression [95]
MUC5AC TTEL90S Strong Biomarker [96]
NPR1 TTM9IYA Strong Biomarker [97]
OSCAR TT71Q5Y Strong Biomarker [98]
PADI3 TTSCHFW Strong Biomarker [99]
PDE4A TTZ97H5 Strong Biomarker [100]
PINX1 TT4FJ3A Strong Altered Expression [101]
PLTP TTZF6SN Strong Altered Expression [102]
PTGS2 TTVKILB Strong Altered Expression [103]
RGMA TTURJV4 Strong Biomarker [104]
SCGB1A1 TTONPVW Strong Biomarker [105]
SLC26A9 TTKRVU0 Strong Biomarker [106]
SLC29A1 TTLXAKE Strong Biomarker [107]
SLC6A14 TTB6H2S Strong Biomarker [108]
SOD2 TT9O4C5 Strong Genetic Variation [109]
TERT TTQY2EJ Strong Biomarker [110]
TGFB1 TTR9XHZ Strong Biomarker [111]
THPO TTCG5PE Strong Biomarker [112]
TNF TTF8CQI Strong Genetic Variation [113]
USP8 TT1J07C Strong Biomarker [114]
ABCG1 TTMWDGU Definitive Biomarker [115]
CEBPB TTUI35N Definitive Biomarker [116]
CXCL9 TTWE5PB Definitive Biomarker [76]
FCGR1A TTZK4I3 Definitive Altered Expression [117]
FST TTDNM9W Definitive Altered Expression [118]
GLRX TTRJCNG Definitive Biomarker [119]
IL37 TTQTX98 Definitive Altered Expression [120]
IRF3 TTYR7OH Definitive Genetic Variation [54]
P2RX4 TT1NLOA Definitive Biomarker [49]
P2RY1 TTA93TL Definitive Biomarker [49]
P2RY2 TTOZHQC Definitive Biomarker [49]
PADI4 TTQHAXM Definitive Biomarker [99]
TFF1 TTNOJIZ Definitive Biomarker [121]
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⏷ Show the Full List of 123 DTT(s)
This Disease Is Related to 5 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC27A5 DT0TQS3 Limited Biomarker [20]
SLC11A1 DT650XW Disputed Genetic Variation [122]
SLC22A4 DT2EG60 moderate Altered Expression [123]
ABCA3 DT2T6VQ Strong Genetic Variation [124]
ATP12A DT5NLZA Strong Biomarker [125]
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This Disease Is Related to 5 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
LDHC DEQG7F9 Limited Biomarker [32]
CYP27B1 DE3FYEM Disputed Altered Expression [126]
QARS1 DEVSTRI moderate Biomarker [127]
ADH5 DEIOH6A Strong Biomarker [128]
MARS1 DE0K52I Strong Genetic Variation [129]
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This Disease Is Related to 141 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ADGRE5 OTTSB84Q Limited Biomarker [32]
ALDH7A1 OTV57BZD Limited Biomarker [130]
BST1 OTAV5SE7 Limited Biomarker [32]
CLEC4D OTT7X1UC Limited Biomarker [32]
CLEC4E OT7P8ICY Limited Biomarker [32]
CRISPLD2 OTVSFHTL Limited Biomarker [131]
ELMOD2 OTO5WT78 Limited Biomarker [132]
ELN OTFSO7PG Limited Biomarker [133]
ENO2 OTRODL0T Limited Biomarker [134]
FLCN OTVM78XM Limited Genetic Variation [135]
GADD45G OT8V1J4M Limited Biomarker [136]
HARS1 OTHOEOTS Limited Biomarker [137]
IRX1 OT0ZN9EJ Limited Biomarker [138]
IRX2 OTBHXXQ2 Limited Biomarker [138]
IRX3 OTLJ48FG Limited Biomarker [138]
IRX5 OT05J514 Limited Biomarker [138]
KLF2 OTIP1UFX Limited Biomarker [139]
PARP9 OT7K4494 Limited Biomarker [20]
PTHLH OTI1JF13 Limited Biomarker [37]
RHOT1 OTBIRR8Q Limited Biomarker [140]
SARS1 OTFKXQ1O Limited Altered Expression [141]
SARS2 OTU4T99W Limited Altered Expression [141]
SCNN1A OTE2KVZV Limited Biomarker [142]
SCNN1B OT61QQTL Limited Biomarker [80]
SCNN1G OTSJYQVQ Limited Biomarker [143]
SEMA4A OT8901H3 Limited Biomarker [144]
SHOX2 OTLCZZJW Limited Posttranslational Modification [145]
SPRY2 OTH0CRCZ Limited Biomarker [146]
STAT5B OTZVPEBT Limited Biomarker [147]
CCL18 OT7JYSK9 Disputed Biomarker [148]
ITGA3 OTBCH21D Disputed Genetic Variation [149]
P2RX2 OT0LF34A Disputed Biomarker [49]
ACD OTC54EPO moderate Biomarker [150]
AHRR OTSJ12W6 moderate Genetic Variation [151]
CGAS OTJYIXNB moderate Genetic Variation [54]
CYBA OT16N9ZO moderate Genetic Variation [152]
EDIL3 OTDVVNS0 moderate Biomarker [153]
EHF OTY6TPWD moderate Biomarker [154]
EPGN OT3EG75W moderate Biomarker [51]
EPRS1 OTXK0FLB moderate Biomarker [127]
IRF7 OTC1A2PQ moderate Genetic Variation [54]
MYH10 OTXN2WXS moderate Biomarker [155]
PELI1 OTMLBCLC moderate Biomarker [156]
PHF14 OTZT3GV1 moderate Genetic Variation [151]
PI3 OT47MTC3 moderate Biomarker [157]
RO60 OTLGM5A8 moderate Biomarker [158]
RYK OTZ3WWZH moderate Biomarker [159]
SFTPA1 OT87XL1U moderate Biomarker [160]
TBX4 OTW58FG4 moderate Genetic Variation [161]
TGIF1 OTN9VHAG moderate Biomarker [51]
A2M OTFTX90K Strong Biomarker [162]
ADGRF5 OTWU7AOO Strong Biomarker [163]
AFF4 OTTL5Y8R Strong Biomarker [164]
AP1S2 OTZHJFYI Strong Genetic Variation [165]
AP3B1 OTYTIH5Q Strong Biomarker [121]
APIP OT8ZABOU Strong Biomarker [166]
ARMH1 OTTJC0D6 Strong Altered Expression [29]
ATP6V0A2 OTJBDX0Y Strong Genetic Variation [167]
BPIFA1 OTQFD2J5 Strong Altered Expression [168]
BPIFB1 OTOZYJMO Strong Genetic Variation [169]
BUD23 OTJS7VU3 Strong Altered Expression [170]
CALB2 OTSNMCG9 Strong Altered Expression [171]
CCDC40 OTFHEUUN Strong Genetic Variation [172]
CHI3L1 OT2Z7VJH Strong Biomarker [173]
CHP1 OTHTXN1A Strong Altered Expression [174]
COPA OTZ1DTXU Strong Genetic Variation [175]
DYM OTQ670WI Strong Biomarker [176]
EBNA1BP2 OTBRVMZH Strong Altered Expression [29]
ELF5 OTLRU8YF Strong Biomarker [154]
FAM13A OTZ6GN0Q Strong Biomarker [177]
FCN1 OTK6ZHXH Strong Biomarker [178]
FLOT1 OT0JPPJZ Strong Altered Expression [179]
FOXA2 OTJOCVOY Strong Biomarker [180]
FOXA3 OTRGT2OT Strong Altered Expression [181]
FOXF1 OT2CJZ5K Strong Altered Expression [182]
FSTL1 OT6KEZUD Strong Biomarker [183]
GFER OTVK43OK Strong Biomarker [184]
GNB3 OTA6HYBA Strong Biomarker [185]
GPX3 OT6PK94R Strong Biomarker [186]
GRAMD2A OTYANSEU Strong Biomarker [187]
GYPA OTABU4YV Strong Genetic Variation [188]
GYPB OTESHUIX Strong Genetic Variation [188]
GYPE OTBHAG6A Strong Genetic Variation [188]
HAND2 OTCXYW4Y Strong Biomarker [189]
HHEX OTLIUVYX Strong Biomarker [190]
HPS1 OTKS5I7T Strong Genetic Variation [191]
HPS4 OTBTW01J Strong Biomarker [192]
IFRD1 OT4SQMLQ Strong Biomarker [193]
IGFBP4 OT2HZRBD Strong Biomarker [194]
IL34 OTZ15VVK Strong Biomarker [195]
INTS4 OT5JQ913 Strong Genetic Variation [122]
IREB2 OT747D24 Strong Biomarker [196]
ITSN1 OT8YF3S5 Strong Biomarker [197]
KLF10 OT4F4UGS Strong Biomarker [97]
LAMP3 OTN0XL3W Strong Altered Expression [198]
MID1 OTWN1PGU Strong Biomarker [199]
MT1E OTXJKU4Y Strong Biomarker [200]
NKX2-1 OTCMEJTA Strong Genetic Variation [201]
NLK OT2LETFS Strong Altered Expression [202]
NPC2 OTE9UEJC Strong Biomarker [203]
NPNT OTFZAO1G Strong Genetic Variation [165]
NRSN1 OT1KKXC8 Strong Altered Expression [174]
OPN1MW OTPJ7LX4 Strong Biomarker [204]
PADI2 OTT40K94 Strong Biomarker [99]
PIR OT8ALXHU Strong Biomarker [205]
PLCB3 OT0OMDEM Strong Genetic Variation [206]
PMAIP1 OTXEE550 Strong Biomarker [207]
PSMD7 OT7PZZ4K Strong Altered Expression [29]
RABEPK OTCZSREH Strong Altered Expression [29]
RETNLB OT9JJQQQ Strong Biomarker [208]
RPL32 OTKRQJT4 Strong Biomarker [209]
SCNN1D OTTX2G9M Strong Genetic Variation [210]
SEMA3B OTCZCPMS Strong Posttranslational Modification [211]
SERPINB1 OT5RDUFO Strong Altered Expression [212]
SFTPA2 OT6SFOMU Strong Biomarker [160]
SFTPB OTOHS07E Strong Biomarker [160]
SH2D1A OTLU49I5 Strong Biomarker [213]
SIGLEC9 OTZC7SIM Strong Biomarker [214]
SMC5 OT91M6N4 Strong Genetic Variation [215]
TAB2 OTPZK76F Strong Biomarker [28]
TFF2 OTRXB19X Strong Biomarker [216]
TINF2 OT861N2N Strong Biomarker [217]
TMED2 OTBLO7RW Strong Altered Expression [174]
TNFAIP6 OT1SLUZH Strong Biomarker [218]
TNMD OTHLVA9G Strong Biomarker [219]
TPPP OTCFMSUF Strong Altered Expression [174]
TRAF1 OTTLM5RU Strong Biomarker [220]
TRIM72 OTFAFXPC Strong Biomarker [221]
ADGRG6 OTY2UBXO Definitive Genetic Variation [222]
ASL OTI2NGQR Definitive Biomarker [223]
ASPRV1 OT8WVIBW Definitive Biomarker [224]
CCNO OT68CH0B Definitive Biomarker [225]
GZMA OT43R33L Definitive Altered Expression [117]
LUM OTSRC874 Definitive Biomarker [226]
MTX1 OTLSDNZO Definitive Biomarker [227]
NPC1 OTRIPICX Definitive Biomarker [228]
NTM OTHF0UQU Definitive Genetic Variation [229]
P2RX5 OTLBR20R Definitive Biomarker [49]
P2RX6 OT1FNTXA Definitive Biomarker [49]
STING1 OTDAP4G0 Definitive Biomarker [230]
STRA6 OT2IDF27 Definitive Biomarker [231]
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⏷ Show the Full List of 141 DOT(s)

References

1 Aminophylline FDA Label
2 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
3 Pirbuterol FDA Label
4 Theophylline FDA Label
5 ClinicalTrials.gov (NCT02249338) Effect of BIIL 284 BS on Patients With Chronic Obstructive Pulmonary Disease (COPD) in Boehringer Ingelheim.
6 ClinicalTrials.gov (NCT00800579) Trial to Assess the Safety, Tolerability and Pharmacokinetics of GS-9411 in Healthy Male Volunteers. U.S. National Institutes of Health.
7 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
8 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2358).
9 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2767).
10 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1788).
11 Ischaemic and pharmacological preconditionings protect liver via adenosine and redox status following hepatic ischaemia/reperfusion in rats.Clin Sci (Lond). 2008 Jul;115(2):69-77. doi: 10.1042/CS20070415.
12 Protective effects of adenosine A2A receptor agonist in ventilator-induced lung injury in rats.Crit Care Med. 2009 Jul;37(7):2235-41. doi: 10.1097/CCM.0b013e3181a55273.
13 Adenosine and hyaluronan promote lung fibrosis and pulmonary hypertension in combined pulmonary fibrosis and emphysema.Dis Model Mech. 2019 May 15;12(5):dmm038711. doi: 10.1242/dmm.038711.
14 Spatial coordination of cell-adhesion molecules and redox cycling of iron in the microvascular inflammatory response to pulmonary injury.Antioxid Redox Signal. 2007 Apr;9(4):483-95. doi: 10.1089/ars.2006.1296.
15 Cyclooxygenase inhibitors attenuate bradykinin-induced vasoconstriction in septic isolated rat lungs.Anesth Analg. 2000 Mar;90(3):625-31. doi: 10.1097/00000539-200003000-00023.
16 Use of monoclonal antibodies to assess expression of anaphylatoxin receptors in rat and murine models of lung inflammation.Exp Toxicol Pathol. 2007 Aug;58(6):419-25. doi: 10.1016/j.etp.2007.03.004. Epub 2007 Jun 1.
17 Association between Mycobacterium avium complex lung disease and serum vitamin D status, antimicrobial peptide levels, and bone mineral density.Medicine (Baltimore). 2018 Sep;97(38):e12463. doi: 10.1097/MD.0000000000012463.
18 Production and effects of alpha-melanocyte-stimulating hormone during acute lung injury.Shock. 2007 Mar;27(3):326-33. doi: 10.1097/01.shk.0000239764.80033.7e.
19 Diagnostic value of CYFRA 21-1 and carcinoembryonic antigen in diagnosis of operable lung cancer from benign lung disease.J Cancer Res Ther. 2018 Jun;14(Supplement):S400-S404. doi: 10.4103/0973-1482.174180.
20 The effect of cigarette smoking on bronchoalveolar lavage protein profiles from patients with different interstitial lung diseases.Panminerva Med. 2020 Jun;62(2):109-115. doi: 10.23736/S0031-0808.19.03754-6. Epub 2019 Sep 24.
21 Activation of corticotropin-releasing factor receptor-2 causes bronchorelaxation and inhibits pulmonary inflammation in mice.FASEB J. 2006 Sep;20(11):1877-9. doi: 10.1096/fj.05-5315fje. Epub 2006 Jul 19.
22 [Effect of Shenqi Fuzheng injection on fractalkine expression in lung tissue of rats with lipopolysaccharide-induced acute lung injury].Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Jan;27(1):55-9.
23 Epigenetic Regulation of IL-17-Induced Chemokines in Lung Epithelial Cells.Mediators Inflamm. 2019 Mar 17;2019:9050965. doi: 10.1155/2019/9050965. eCollection 2019.
24 Health insurance and use of recommended routine care in adults with cystic fibrosis.Clin Respir J. 2018 May;12(5):1981-1988. doi: 10.1111/crj.12767. Epub 2018 Feb 9.
25 Reducing endoglin activity limits calcineurin and TRPC-6 expression and improves survival in a mouse model of right ventricular pressure overload.J Am Heart Assoc. 2014 Jul 11;3(4):e000965. doi: 10.1161/JAHA.114.000965.
26 Circulating actin-gelsolin complexes following oleic acid-induced lung injury.Am J Pathol. 1988 Feb;130(2):261-7.
27 Prenatal administration of retinoic acid upregulates insulin-like growth factor receptors in the nitrofen-induced hypoplastic lung.Birth Defects Res B Dev Reprod Toxicol. 2011 Apr;92(2):148-51. doi: 10.1002/bdrb.20293. Epub 2011 Mar 23.
28 Overexpression of miR-155-5p Inhibits the Proliferation and Migration of IL-13-Induced Human Bronchial Smooth Muscle Cells by Suppressing TGF--Activated Kinase 1/MAP3K7-Binding Protein 2.Allergy Asthma Immunol Res. 2018 May;10(3):260-267. doi: 10.4168/aair.2018.10.3.260.
29 Interleukin 23/interleukin 17 axis activated by Mycobacterium avium complex (MAC) is attenuated in patients with MAC-lung disease.Tuberculosis (Edinb). 2018 May;110:7-14. doi: 10.1016/j.tube.2018.03.001. Epub 2018 Mar 3.
30 Activation of type II alveolar epithelial cells during acute endotoxemia.Am J Physiol Lung Cell Mol Physiol. 2002 Apr;282(4):L872-80. doi: 10.1152/ajplung.00217.2001.
31 LAIR-1 Limits Neutrophilic Airway Inflammation.Front Immunol. 2019 Apr 26;10:842. doi: 10.3389/fimmu.2019.00842. eCollection 2019.
32 Blood gene expression profiling detects silica exposure and toxicity.Toxicol Sci. 2011 Aug;122(2):253-64. doi: 10.1093/toxsci/kfr125. Epub 2011 May 19.
33 Structure-Function Analysis of the Non-Muscle Myosin Light Chain Kinase (nmMLCK) Isoform by NMR Spectroscopy and Molecular Modeling: Influence of MYLK Variants.PLoS One. 2015 Jun 25;10(6):e0130515. doi: 10.1371/journal.pone.0130515. eCollection 2015.
34 VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5.Genes Dev. 2008 Jun 1;22(11):1465-77. doi: 10.1101/gad.479408.
35 Abnormal platelet-derived growth factor signaling accounting for lung hypoplasia in experimental congenital diaphragmatic hernia.J Pediatr Surg. 2010 Oct;45(10):1989-94. doi: 10.1016/j.jpedsurg.2010.06.014.
36 Asbestos-induced peribronchiolar cell proliferation and cytokine production are attenuated in lungs of protein kinase C-delta knockout mice.Am J Pathol. 2007 Jan;170(1):140-51. doi: 10.2353/ajpath.2007.060381.
37 Prenatal treatment with retinoic acid activates parathyroid hormone-related protein signaling in the nitrofen-induced hypoplastic lung.Pediatr Surg Int. 2011 Jan;27(1):47-52. doi: 10.1007/s00383-010-2726-y.
38 Surfactant protein D multimerization and gene polymorphism in COPD and asthma. Respirology. 2018 Mar;23(3):298-305.
39 A Joint Location-Scale Test Improves Power to Detect Associated SNPs, Gene Sets, and Pathways.Am J Hum Genet. 2015 Jul 2;97(1):125-38. doi: 10.1016/j.ajhg.2015.05.015.
40 Lung disease in STAT3 hyper-IgE syndrome requires intense therapy.Allergy. 2019 Sep;74(9):1691-1702. doi: 10.1111/all.13753. Epub 2019 Apr 4.
41 Comparison of pro- and anti-inflammatory responses in paired human primary airway epithelial cells and alveolar macrophages.Respir Res. 2018 Jun 25;19(1):126. doi: 10.1186/s12931-018-0825-9.
42 TRPC6 modulates adhesion of neutrophils to airway epithelial cells via NF-B activation and ICAM-1 expression with ozone exposure.Exp Cell Res. 2019 Apr 15;377(1-2):56-66. doi: 10.1016/j.yexcr.2019.02.013. Epub 2019 Feb 16.
43 Epithelial alarmin levels in exhaled breath condensate in patients with idiopathic pulmonary fibrosis: A pilot study.Clin Respir J. 2019 Oct;13(10):652-656. doi: 10.1111/crj.13075. Epub 2019 Aug 19.
44 Bactericidal/Permeability-increasing protein fold-containing family member A1 in airway host protection and respiratory disease.Am J Respir Cell Mol Biol. 2015 May;52(5):525-34. doi: 10.1165/rcmb.2014-0297RT.
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