General Information of Disease (ID: DISB4B0F)

Disease Name Retinopathy
Synonyms eye disease of retina; retina eye disease; retinopathy
Disease Class 9B71: Retinopathy
Definition Any disease or disorder of the retina.
Disease Hierarchy
DISB52BH: Eye disorder
DISCFBRD: Neurological disorder
DISB4B0F: Retinopathy
ICD Code
ICD-11
ICD-11: 9B71
Expand ICD-11
'9B71
Expand ICD-9
362
Disease Identifiers
MONDO ID
MONDO_0005283
MESH ID
D012164
UMLS CUI
C0035309
MedGen ID
11209
HPO ID
HP:0000488
SNOMED CT ID
29555009

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Finasteride DMWV3TZ Approved Small molecular drug [1]
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This Disease is Treated as An Indication in 3 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
SHP607 DMX54C8 Phase 2 NA [2]
ReN-003 DMAX4C1 Phase 1/2 NA [3]
RST-001 DM8B70M Phase 1/2 NA [4]
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This Disease is Treated as An Indication in 1 Patented Agent(s)
Drug Name Drug ID Highest Status Drug Type REF
PMID28621580-Compound-WO2015089220C70 DMX96FI Patented Small molecular drug [5]
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This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
SIR-1076 DM59FWZ Preclinical NA [6]
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This Disease is Treated as An Indication in 7 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
CytoRet DMNDZ42 Investigative NA [3]
Gene therapy, retinopathy, DME4R6W Investigative NA [3]
INDUS-815C DMLJ645 Investigative NA [7]
LPO-1010CSR DMHO5DD Investigative NA [3]
SF-106 DM0KVVH Investigative NA [3]
SF-113 DM10KHX Investigative NA [3]
Superoxide dismutase mimetics DMG48G8 Investigative NA [3]
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⏷ Show the Full List of 7 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 100 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
APOC3 TTXOZQ1 Limited Biomarker [8]
CNGB3 TT0LJCG Limited Genetic Variation [9]
FANCF TTNZKFJ Limited Biomarker [10]
GM2A TTGOFW6 Limited Biomarker [11]
HCAR1 TTVK4ZO Limited Biomarker [12]
HEXB TTKIBKM Limited Biomarker [11]
ICAM1 TTA1L39 Limited Biomarker [13]
NPR1 TTM9IYA Limited Altered Expression [14]
NPY2R TTJ6WK9 Limited Biomarker [15]
PKD2L1 TTAHD89 Limited Biomarker [16]
PSMB10 TTPNACM Limited Biomarker [17]
SH3GL1 TTTYNAM Limited Biomarker [18]
SIRT1 TTUF2HO Limited Biomarker [19]
SLC22A2 TT0XOJN Limited Biomarker [20]
STK38 TT27XFN Limited Genetic Variation [21]
TRPC5 TT32NQ1 Limited Biomarker [22]
AMD1 TTBFROQ moderate Biomarker [23]
APLNR TTJ8E43 moderate Biomarker [24]
C1QBP TTWTD7F moderate Biomarker [25]
CASP3 TTPF2QI moderate Biomarker [26]
CETP TTFQAYR moderate Genetic Variation [27]
CFB TTA0P7K moderate Genetic Variation [28]
CHM TTOA18V moderate Biomarker [29]
EDN2 TTMR0OP moderate Biomarker [30]
GRB2 TTEYRJ9 moderate Altered Expression [31]
HCAR2 TTWNV8U moderate Biomarker [32]
IGFBP6 TTLAYV8 moderate Biomarker [25]
LTB TTHQ6US moderate Biomarker [25]
MANF TT56RYE moderate Biomarker [33]
NCK1 TTMA3VF moderate Biomarker [34]
NPTX2 TTNJ5A6 moderate Genetic Variation [35]
NR1D1 TTAD1O8 moderate Biomarker [36]
PLD2 TTRLMKF moderate Biomarker [37]
SLC11A2 TT2IS7P moderate Biomarker [38]
SLC19A2 TT2A1DZ moderate Biomarker [39]
SLC19A3 TT9BTWM moderate Genetic Variation [39]
TAAR5 TTCO25G moderate Genetic Variation [40]
UCHL1 TTX9IFP moderate Biomarker [26]
UTS2R TTW5UDX moderate Genetic Variation [41]
VEGFB TTPJQHE moderate Biomarker [42]
ADAM9 TTTYQNS Strong Biomarker [43]
AKR1B1 TTFBNVI Strong Biomarker [44]
ANGPTL3 TT59GO7 Strong Biomarker [45]
ANGPTL4 TTWALY5 Strong Biomarker [45]
ARG2 TTV1AG6 Strong Biomarker [46]
ATF4 TTQCKWT Strong Biomarker [47]
CCN1 TTPK79J Strong Biomarker [48]
CDH3 TTARMD9 Strong Biomarker [49]
CFH TTUW6OP Strong Genetic Variation [50]
CGA TTFC29G Strong Biomarker [51]
CGB3 TTUH273 Strong Biomarker [51]
CHAT TTKYFSB Strong Biomarker [52]
CHRM3 TTQ13Z5 Strong Genetic Variation [47]
CLN3 TTORF9W Strong Genetic Variation [53]
CNGA3 TTW0QOV Strong Biomarker [54]
CNTF TTGEM5Q Strong Altered Expression [55]
CTNS TT1W2ZS Strong Genetic Variation [56]
CYBB TT5T8MR Strong Biomarker [57]
CYP2C9 TTR40YJ Strong Posttranslational Modification [58]
EPHB4 TTI4ZX2 Strong Biomarker [59]
GAD2 TT7UY6K Strong Altered Expression [60]
GCK TTDLNGZ Strong Genetic Variation [61]
GFAP TTI6FFX Strong Genetic Variation [62]
GLP1R TTVIMDE Strong Biomarker [63]
GUCY2D TTWNFC2 Strong Genetic Variation [64]
HMOX1 TTI6V2A Strong Biomarker [52]
HNF1A TT01M3K Strong Genetic Variation [65]
HNF4A TT2F3CD Strong Genetic Variation [61]
IDUA TT0IUKX Strong Biomarker [66]
IFNA2 TTSIUJ9 Strong Biomarker [67]
IKBKB TTJ3E9X Strong Biomarker [68]
IL37 TTQTX98 Strong Biomarker [69]
INS TTZOPHG Strong Biomarker [70]
KIF11 TTBGTCW Strong Biomarker [71]
LAMP2 TTULDG7 Strong Biomarker [72]
MAP3K8 TTGECUM Strong Biomarker [73]
MAPKAPK3 TTFS4VU Strong Genetic Variation [74]
MTNR1A TT0WAIE Strong Biomarker [75]
NES TTHZ752 Strong Genetic Variation [76]
NOS2 TTF10I9 Strong Biomarker [52]
PAOX TTNQ760 Strong Biomarker [77]
PDGFB TTQA6SX Strong Therapeutic [78]
PGF TT48I1Y Strong Biomarker [79]
PLA2G7 TTDNFMT Strong Biomarker [80]
PTPRC TTUS45N Strong Biomarker [81]
RAPGEF3 TTOE7I0 Strong Altered Expression [82]
RHO TTH0KSX Strong Genetic Variation [83]
RPE65 TTBOH16 Strong Biomarker [84]
RPGR TTHBDA9 Strong Biomarker [85]
RS1 TTT2CZY Strong Biomarker [86]
SERPINF1 TTR59S1 Strong Genetic Variation [87]
SIGMAR1 TT5TPI6 Strong Biomarker [88]
SUCNR1 TT4FX9Y Strong Altered Expression [89]
UBC TTBP3XA Strong Biomarker [90]
USH2A TTVCLLA Strong Biomarker [91]
EHMT1 TTOFXD7 Definitive Genetic Variation [92]
FGF21 TTQ916P Definitive Biomarker [93]
NRG4 TTWAGKJ Definitive Genetic Variation [94]
SCG3 TTY5R9H Definitive Biomarker [95]
TNF TTF8CQI Definitive Biomarker [96]
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⏷ Show the Full List of 100 DTT(s)
This Disease Is Related to 5 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCA12 DT7LDG0 moderate Biomarker [97]
SLC14A2 DT8QC7K moderate Genetic Variation [41]
SLC24A1 DTJZ7M5 moderate Genetic Variation [98]
SLC9C1 DT9J8DO Strong Biomarker [99]
SLC6A6 DTHWCVA Definitive Altered Expression [100]
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This Disease Is Related to 3 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
SULT2A1 DE0P6LK Limited Altered Expression [101]
CYP2C18 DEZMWRE Strong Posttranslational Modification [58]
RDH5 DESI4OK Strong Biomarker [102]
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This Disease Is Related to 162 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AARS2 OTOB0KSG Limited Genetic Variation [103]
AGTRAP OT02N7LD Limited Biomarker [104]
AIPL1 OT4VBD78 Limited Genetic Variation [105]
AKT1S1 OT4JHN4Y Limited Posttranslational Modification [106]
CASK OT8EF7ZF Limited Biomarker [107]
CD200R1 OT65Q9M6 Limited Biomarker [108]
CRB2 OTG0L2CE Limited Biomarker [109]
CYGB OTX153DQ Limited Biomarker [110]
DGKI OTDZ602D Limited Biomarker [111]
DHX32 OTDYB66V Limited Autosomal recessive [112]
DLEU7 OTVKX1YP Limited Genetic Variation [113]
DSCAML1 OT7QURQT Limited Autosomal recessive [112]
ENOX1 OT4WOLA8 Limited Altered Expression [114]
HEMGN OTZPYUOY Limited Genetic Variation [21]
IL26 OT2WYCW4 Limited Biomarker [115]
KCNJ13 OTG1CNND Limited Biomarker [116]
MTG1 OTC9U1LI Limited Genetic Variation [117]
MUCL3 OTGAD3I0 Limited Biomarker [118]
PEX1 OTQJF0V7 Limited Genetic Variation [119]
POU2F2 OTPV0J0C Limited Biomarker [20]
RP1 OTDDT69Y Limited Genetic Variation [120]
SYTL4 OT7MX5IK Limited X-linked [112]
TMED7 OTONO8E6 Limited Autosomal recessive [112]
ADCY10 OTYSTB0R moderate Biomarker [32]
AGBL5 OTMLXQZ4 moderate Biomarker [121]
ALDH18A1 OT6W40XU moderate Genetic Variation [122]
ALMS1 OTW66JKS moderate Biomarker [123]
ARL6 OTLV3SBS moderate Biomarker [121]
ATP1B1 OTTO6ZP4 moderate Altered Expression [124]
BBS2 OTPF9JIB moderate Biomarker [125]
BBS4 OT0D3JC0 moderate Biomarker [126]
CABP4 OTL0TRR5 moderate Biomarker [127]
CAVIN2 OTFHHDRU moderate Altered Expression [128]
CCDC6 OTXRQDYG moderate Biomarker [129]
CENPK OTKPUF8K moderate Biomarker [25]
CERKL OTG4YGBR moderate Biomarker [130]
CHMP2B OTZA7RJB moderate Biomarker [38]
COL8A1 OTWBTED2 moderate Genetic Variation [131]
COL8A2 OTASWJ69 moderate Genetic Variation [131]
DCT OTYVNTBG moderate Biomarker [132]
DMRT1 OT5PU9U1 moderate Biomarker [38]
DNAJC13 OTYAVVJ6 moderate Biomarker [133]
DRAM2 OTBOCZH8 moderate Genetic Variation [134]
EDIL3 OTDVVNS0 moderate Biomarker [135]
EMP2 OTPS2H0L moderate Altered Expression [136]
ERG OTOTX9VU moderate Altered Expression [137]
GRK1 OT7MPSG7 moderate Biomarker [138]
HDGFL2 OTWX2GHS moderate Biomarker [139]
IL1F10 OTJAASGC moderate Biomarker [140]
IQCB1 OTYQ28V9 moderate Biomarker [141]
JAM3 OTX0F9QL moderate Biomarker [142]
KLHL7 OT2OF1O8 moderate Genetic Variation [143]
LAMB2 OT71OI2Y moderate Genetic Variation [144]
MAGEC3 OT0KDWZN moderate Biomarker [32]
MAK OTEU2G41 moderate Genetic Variation [145]
MAP2K3 OTI2OREX moderate Therapeutic [146]
MEF2C OTZGF1Y5 moderate Biomarker [147]
MLXIPL OTR9MLLW moderate Biomarker [148]
MPDZ OT9WY1QM moderate Biomarker [149]
MYO5C OTKLOCWZ moderate Genetic Variation [150]
MYO7A OTBZSPEL moderate Genetic Variation [151]
NCK2 OTUYPF55 moderate Biomarker [34]
ND5 OT45LW1K moderate Genetic Variation [152]
NFATC4 OTTDCUAO moderate Biomarker [153]
NPHP3 OT8U8ELA moderate Biomarker [133]
NR2E3 OTO3GBHQ moderate Genetic Variation [40]
NRDC OTWBBCXO moderate Biomarker [154]
NXNL1 OT92AILF moderate Biomarker [155]
NXPH3 OTG82U2K moderate Biomarker [133]
PCARE OTUSRSB5 moderate Genetic Variation [156]
PHLDA2 OTMV9DPP moderate Biomarker [157]
POMGNT1 OTBNOUZC moderate Genetic Variation [158]
PRPF31 OTSJ0Z1Y moderate Altered Expression [159]
RCAN1 OT1MVXC7 moderate Biomarker [160]
RDH8 OTSFFV9B moderate Biomarker [161]
RGCC OTYJMLWM moderate Biomarker [162]
RP1L1 OTRKSQWQ moderate Genetic Variation [163]
RPE OT0XT3JU moderate Biomarker [164]
RPL41 OTFW5IFO moderate Genetic Variation [47]
SAGE1 OT4H6FFA moderate Genetic Variation [165]
SEMA3C OTEGUY7F moderate Biomarker [166]
SERPINA3 OT9BP2S0 moderate Therapeutic [81]
SIRT4 OT5S0J23 moderate Biomarker [167]
SIVA1 OTDT0XZK moderate Biomarker [168]
SNRNP200 OTSAU864 moderate Biomarker [169]
TAS2R38 OTX5MM36 moderate Biomarker [129]
TENT5A OTSYF511 moderate Biomarker [118]
TFPT OTM70AK1 moderate Altered Expression [159]
TTLL5 OTUKOVEM moderate Genetic Variation [170]
ABHD12 OTDP4F02 Strong Biomarker [171]
ACP1 OTJ9CKLU Strong Biomarker [172]
ADAMTS18 OTRMFI04 Strong Genetic Variation [173]
ADGRV1 OTLVXHHP Strong Biomarker [174]
AHI1 OT8K2YWY Strong Biomarker [175]
AQP4 OTA9MYD5 Strong Biomarker [176]
ARL13B OT9PYPV1 Strong Genetic Variation [177]
ATOH7 OTUBW5PV Strong Biomarker [178]
ATP6 OTPHOGLX Strong Genetic Variation [179]
ATXN1 OTQF0HNR Strong Biomarker [180]
BBS1 OTXSXB1K Strong Genetic Variation [181]
BEST1 OTWHE1ZC Strong Genetic Variation [182]
C1QTNF5 OTLKU5I2 Strong Biomarker [183]
CCDC66 OTE8VSSO Strong Biomarker [184]
CDK16 OTUBXIIT Strong Biomarker [185]
COL9A1 OTWBR27Y Strong Biomarker [186]
CRX OTH435SV Strong Biomarker [187]
DDHD1 OTWTHOWK Strong Biomarker [188]
EYS OT0NBPL5 Strong Biomarker [189]
FAM161A OTF5ZRYJ Strong Biomarker [190]
FAM72A OTBZYSR3 Strong Biomarker [191]
FAM72B OT6AOG64 Strong Biomarker [191]
FRMD3 OT0CD2GG Strong Biomarker [192]
FZD4 OTGLZIE0 Strong Biomarker [193]
GNB3 OTA6HYBA Strong Biomarker [194]
GNGT2 OTRI3Q10 Strong Genetic Variation [195]
GOLGA6A OTHU9MRX Strong Genetic Variation [92]
GUCA1B OT85S0J3 Strong Genetic Variation [196]
IFT52 OTFIVV9A Strong Genetic Variation [197]
IL2RG OTRZ3OMY Strong Genetic Variation [195]
IMPG1 OT12HBL0 Strong Biomarker [198]
ITM2B OTMXEPXB Strong Genetic Variation [199]
KCNV2 OTLS8OU5 Strong Biomarker [200]
LRAT OTB7CJKY Strong Biomarker [201]
NDP OTGDJ4US Strong Biomarker [193]
NRL OT65MFKQ Strong Genetic Variation [202]
NYX OTAGXLYP Strong Genetic Variation [203]
OCLN OTSUTVWL Strong Altered Expression [62]
OTX2 OTTV05B1 Strong Biomarker [204]
PDC OT1UUVYY Strong Biomarker [205]
PDE6C OTE7EVWQ Strong Biomarker [206]
PDZD7 OTX3VAOB Strong Biomarker [207]
PIWIL4 OTDA9MY0 Strong Biomarker [208]
PKD2 OTIXBU8H Strong Biomarker [209]
PLVAP OTAQGWYA Strong Altered Expression [210]
PLXNA2 OTNNBJMQ Strong Biomarker [211]
POC1B OTDIMIRZ Strong Biomarker [212]
POLE3 OTOELRF6 Strong Biomarker [191]
PROCR OTRHED17 Strong Altered Expression [213]
PRPH OT6VUH78 Strong Genetic Variation [214]
PTCH1 OTMG07H5 Strong Biomarker [129]
RAX2 OT1HD6CF Strong Genetic Variation [215]
RBP3 OTIWM4GT Strong Biomarker [216]
RCBTB1 OTAYELI8 Strong Genetic Variation [92]
RGR OTKCF5AZ Strong Genetic Variation [217]
RLBP1 OTCY4D6B Strong Genetic Variation [218]
RPGRIP1 OTABESO9 Strong Biomarker [219]
RPS27A OTIIGGZ2 Strong Biomarker [90]
SCARA5 OTOVA96E Strong Biomarker [220]
ST3GAL4 OTNENJZQ Strong Biomarker [221]
THY1 OTVONVTB Strong Biomarker [52]
TREX1 OTQG7K12 Strong Genetic Variation [222]
TSPAN12 OTF9I3CX Strong Biomarker [223]
COL4A5 OTHG60RE Definitive Genetic Variation [224]
DDOST OT39PDMS Definitive Altered Expression [225]
PNPLA2 OTR3ERMR Definitive Altered Expression [62]
POLD4 OTG578YH Definitive Biomarker [191]
POLE4 OTCMWUT6 Definitive Biomarker [191]
RD3 OT2L9Y6M Definitive Genetic Variation [226]
RDH12 OTELFRRJ Definitive Biomarker [227]
ROM1 OTE7H0YV Definitive Altered Expression [228]
SDCCAG8 OTV2ZGV9 Definitive Biomarker [229]
TIMP3 OTDGQAD1 Definitive Genetic Variation [230]
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⏷ Show the Full List of 162 DOT(s)

References

1 Finasteride FDA Label
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
4 ClinicalTrials.gov (NCT02556736) RST-001 Phase I/II Trial for Retinitis Pigmentosa.
5 VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Sep;27(9):987-1004.
6 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028168)
7 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2708).
8 Apolipoprotein C-III protein concentrations and gene polymorphisms in Type 1 diabetes: associations with microvascular disease complications in the DCCT/EDIC cohort.J Diabetes Complications. 2005 Jan-Feb;19(1):18-25. doi: 10.1016/j.jdiacomp.2004.04.005.
9 An early nonsense mutation facilitates the expression of a short isoform of CNGA3 by alternative translation initiation.Exp Eye Res. 2018 Jun;171:48-53. doi: 10.1016/j.exer.2018.02.027. Epub 2018 Feb 27.
10 Evaluation of Hydroxychloroquine Retinopathy Using Ultra-Widefield Fundus Autofluorescence: Peripheral Findings in the Retinopathy.Am J Ophthalmol. 2020 Jan;209:35-44. doi: 10.1016/j.ajo.2019.09.008. Epub 2019 Sep 14.
11 Pursuing type 1 diabetes mellitus and related complications through urinary proteomics.Transl Res. 2014 Mar;163(3):188-99. doi: 10.1016/j.trsl.2013.09.005. Epub 2013 Oct 3.
12 Mller Cell-Localized G-Protein-Coupled Receptor 81 (Hydroxycarboxylic Acid Receptor 1) Regulates Inner Retinal Vasculature via Norrin/Wnt Pathways.Am J Pathol. 2019 Sep;189(9):1878-1896. doi: 10.1016/j.ajpath.2019.05.016. Epub 2019 Jun 18.
13 Aqueous Humor Cytokine Levels and Anatomic Response to Intravitreal Ranibizumab in Diabetic Macular Edema.JAMA Ophthalmol. 2018 Apr 1;136(4):382-388. doi: 10.1001/jamaophthalmol.2018.0179.
14 Natriuretic Peptides Attenuate Retinal Pathological Neovascularization Via Cyclic Guanosine Monophosphate Signaling in Pericytes and Astrocytes.Arterioscler Thromb Vasc Biol. 2020 Jan;40(1):159-174. doi: 10.1161/ATVBAHA.119.313400. Epub 2019 Oct 17.
15 Neuropeptide Y expression in a mouse model of oxygen-induced retinopathy.Clin Exp Ophthalmol. 2002 Dec;30(6):424-9. doi: 10.1046/j.1442-9071.2002.00573.x.
16 Ocular biocompatibility of dexamethasone acetate loaded poly(-caprolactone) nanofibers.Eur J Pharm Biopharm. 2019 Sep;142:20-30. doi: 10.1016/j.ejpb.2019.05.010. Epub 2019 May 24.
17 The immunoproteasome subunit LMP10 mediates angiotensin II-induced retinopathy in mice.Redox Biol. 2018 Jun;16:129-138. doi: 10.1016/j.redox.2018.02.022. Epub 2018 Mar 1.
18 Endophilin-A2 dependent VEGFR2 endocytosis promotes sprouting angiogenesis.Nat Commun. 2019 May 28;10(1):2350. doi: 10.1038/s41467-019-10359-x.
19 The mechanistic target of rapamycin (mTOR) and the silent mating-type information regulation 2 homolog 1 (SIRT1): oversight for neurodegenerative disorders.Biochem Soc Trans. 2018 Apr 17;46(2):351-360. doi: 10.1042/BST20170121. Epub 2018 Mar 9.
20 OPTICAL COHERENCE TOMOGRAPHY 2: Diagnostic Tool to Study Peripheral Vitreoretinal Pathologies.Retina. 2019 Feb;39(2):415-421. doi: 10.1097/IAE.0000000000001953.
21 Detection of Subclinical Diabetic Retinopathy by Fine Structure Analysis of Retinal Images.J Ophthalmol. 2019 Jul 4;2019:5171965. doi: 10.1155/2019/5171965. eCollection 2019.
22 The TRPC5 channel regulates angiogenesis and promotes recovery from ischemic injury in mice.J Biol Chem. 2019 Jan 4;294(1):28-37. doi: 10.1074/jbc.RA118.005392. Epub 2018 Nov 9.
23 Characterization and Regulation of Carrier Proteins of Mitochondrial Glutathione Uptake in Human Retinal Pigment Epithelium Cells.Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):500-516. doi: 10.1167/iovs.18-25686.
24 An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice.Sci Rep. 2017 Nov 8;7(1):15062. doi: 10.1038/s41598-017-15602-3.
25 Quantification and localization of the IGF/insulin system expression in retinal blood vessels and neurons during oxygen-induced retinopathy in mice.Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1831-7. doi: 10.1167/iovs.08-2903. Epub 2008 Nov 7.
26 Changes in ocular aquaporin-4 (AQP4) expression following retinal injury.Mol Vis. 2008 Sep 25;14:1770-83.
27 HDL subclasses and the common CETP TaqIB variant predict the incidence of microangiopatic complications in type 2 diabetic women: A 9years follow-up study.Diabetes Res Clin Pract. 2017 Oct;132:108-117. doi: 10.1016/j.diabres.2017.07.026. Epub 2017 Jul 28.
28 Association of CFH and CFB gene polymorphisms with retinopathy in type 2 diabetic patients.Mediators Inflamm. 2013;2013:748435. doi: 10.1155/2013/748435. Epub 2013 Jun 24.
29 Remodeling of the human retina in choroideremia: rab escort protein 1 (REP-1) mutations.Invest Ophthalmol Vis Sci. 2006 Sep;47(9):4113-20. doi: 10.1167/iovs.06-0424.
30 Endothelin-2 Injures the Blood-Retinal Barrier and Macroglial Mller Cells: Interactions with Angiotensin II, Aldosterone, and NADPH Oxidase.Am J Pathol. 2018 Mar;188(3):805-817. doi: 10.1016/j.ajpath.2017.11.009. Epub 2017 Dec 15.
31 Genome-wide association study for sight-threatening diabetic retinopathy reveals association with genetic variation near the GRB2 gene.Diabetologia. 2015 Oct;58(10):2288-97. doi: 10.1007/s00125-015-3697-2. Epub 2015 Jul 19.
32 Constitutive expression of HCA(2) in human retina and primary human retinal pigment epithelial cells.Curr Eye Res. 2014 May;39(5):487-92. doi: 10.3109/02713683.2013.848900. Epub 2013 Nov 11.
33 Identification of Mesencephalic Astrocyte-Derived Neurotrophic Factor as a Novel Neuroprotective Factor for Retinal Ganglion Cells.Front Mol Neurosci. 2017 Mar 17;10:76. doi: 10.3389/fnmol.2017.00076. eCollection 2017.
34 NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy.Nat Commun. 2018 Aug 27;9(1):3463. doi: 10.1038/s41467-018-05926-7.
35 Infantile spasms with basal ganglia MRI hypersignal may reveal mitochondrial disorder due to T8993G MT DNA mutation.Neuropediatrics. 2003 Jun;34(5):265-9. doi: 10.1055/s-2003-43258.
36 Modifier genes as therapeutics: the nuclear hormone receptor Rev Erb alpha (Nr1d1) rescues Nr2e3 associated retinal disease.PLoS One. 2014 Jan 31;9(1):e87942. doi: 10.1371/journal.pone.0087942. eCollection 2014.
37 Endothelial deletion of phospholipase D2 reduces hypoxic response and pathological angiogenesis.Arterioscler Thromb Vasc Biol. 2014 Aug;34(8):1697-703. doi: 10.1161/ATVBAHA.114.303416. Epub 2014 Jun 19.
38 The role and function of HDL in patients with diabetes mellitus and the related cardiovascular risk.Lipids Health Dis. 2017 Oct 30;16(1):207. doi: 10.1186/s12944-017-0594-3.
39 Variation in SLC19A3 and Protection From Microvascular Damage in Type 1 Diabetes.Diabetes. 2016 Apr;65(4):1022-30. doi: 10.2337/db15-1247. Epub 2015 Dec 30.
40 Heterodimers of photoreceptor-specific nuclear receptor (PNR/NR2E3) and peroxisome proliferator-activated receptor- (PPAR) are disrupted by retinal disease-associated mutations.Cell Death Dis. 2017 Mar 16;8(3):e2677. doi: 10.1038/cddis.2017.98.
41 Association of VEGF and eNOS gene polymorphisms in type 2 diabetic retinopathy.Mol Vis. 2006 Apr 11;12:336-41.
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