Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMAI95U)

Drug Name
PMID25656651-Compound-5 Drug Info
Indication
Disease Entry ICD 11 Status REF
Chronic myeloid leukaemia 2A20 Patented [1]
Cross-matching ID
PubChem CID
24826799
ChEBI ID
CHEBI:78543
CAS Number
CAS 943319-70-8
TTD Drug ID
DMAI95U
ACDINA Drug ID
D00541

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Fusion protein Bcr-Abl (Bcr-Abl)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [8]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [8]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [9]
Asciminib DM7EVUF Chronic myeloid leukaemia 2A20 Approved [10]
Radotinib DMWA74Y leukaemia 2A60-2B33 Phase 3 [11]
ABL 001 DMMF5K4 Chronic myeloid leukaemia 2A20 Phase 3 [12]
ICLUSIG DM1SQSE Acute lymphoblastic leukaemia 2A85 Phase 3 [13]
Bafetinib DM7586F Bone disease FC0Z Phase 2 [14]
AN-019 DMJ7QP8 Chronic myelogenous leukaemia 2A20.0 Phase 2 [15]
HQP1351 DMQ30X2 Chronic myeloid leukaemia 2A20 Phase 2 [16]
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Drug(s) Affected By Tyrosine-protein kinase ABL1 (ABL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [17]
Anagrelide DMSQ8MD Thrombocythemia 3B63 Approved [17]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [18]
Quercetin DM3NC4M Obesity 5B81 Approved [19]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [20]
Testosterone DM7HUNW Hot flushes GA30 Approved [21]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [22]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [21]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [23]
Capsaicin DMGMF6V Back pain ME84.Z Approved [24]
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Drug(s) Affected By Macrophage colony-stimulating factor 1 receptor (CSF1R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [33]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
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Drug(s) Affected By Proto-oncogene tyrosine-protein kinase receptor Ret (RET)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [35]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [36]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [37]
Estrone DM5T6US Acne vulgaris ED80 Approved [36]
Methazolamide DM7J2TA Glaucoma/ocular hypertension 9C61 Approved [35]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [38]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
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Drug(s) Affected By Platelet-derived growth factor receptor beta (PDGFRB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [42]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Folic Acid DMEMBJC Colorectal carcinoma Approved [45]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [46]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [47]
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Drug(s) Affected By Fibroblast growth factor receptor 1 (FGFR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [52]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [52]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
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Drug(s) Affected By Proto-oncogene tyrosine-protein kinase Src (SRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosutinib DMTI8YE Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [54]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [55]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Quercetin DM3NC4M Obesity 5B81 Approved [56]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [20]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [57]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [58]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [59]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
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Drug(s) Affected By Serine/threonine-protein kinase B-raf (BRAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [60]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [42]
Leflunomide DMR8ONJ Arthritis FA20 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [63]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [64]
Famotidine DMRL3AB Gastric ulcer DA60 Approved [65]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [66]
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Drug(s) Affected By Platelet-derived growth factor receptor alpha (PDGFRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [70]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Folic Acid DMEMBJC Colorectal carcinoma Approved [72]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [74]
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Drug(s) Affected By Vascular endothelial growth factor receptor 1 (FLT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [77]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Haloperidol DM96SE0 Delirium Approved [78]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [30]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [79]
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Drug(s) Affected By Fibroblast growth factor receptor 2 (FGFR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [52]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [52]
Testosterone DM7HUNW Hot flushes GA30 Approved [21]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
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Drug(s) Affected By Fibroblast growth factor receptor 4 (FGFR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [83]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [85]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [81]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [46]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
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Drug(s) Affected By Fibroblast growth factor receptor 3 (FGFR3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [89]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [90]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [52]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [52]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [92]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
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Drug(s) Affected By Ephrin type-A receptor 2 (EPHA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [25]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Leflunomide DMR8ONJ Arthritis FA20 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [23]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [93]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [94]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
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Drug(s) Affected By Ephrin type-A receptor 3 (EPHA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [95]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [96]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [96]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [97]
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Drug(s) Affected By Vascular endothelial growth factor receptor 3 (FLT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [98]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [99]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [100]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [101]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [103]
Scriptaid DM9JZ21 Solid tumour/cancer 2A00-2F9Z Preclinical [104]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [105]
Nitrobenzanthrone DMN6L70 N. A. N. A. Investigative [106]
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Drug(s) Affected By Vascular endothelial growth factor receptor 2 (KDR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [107]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [108]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [109]
Haloperidol DM96SE0 Delirium Approved [78]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Clozapine DMFC71L Schizophrenia 6A20 Approved [78]
Menthol DMG2KW7 Back pain ME84.Z Approved [110]
Orlistat DMRJSP8 Obesity 5B81 Approved [111]
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Drug(s) Affected By Receptor-type tyrosine-protein kinase FLT3 (FLT3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quizartinib DM8Y4JS Acute myeloid leukaemia 2A60 Approved [112]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [113]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [107]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [114]
Venetoclax DM8I94Y Chronic lymphocytic leukaemia 2A82.0 Approved [115]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [116]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [117]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [118]
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Drug(s) Affected By Angiopoietin-1 receptor (TEK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [119]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [119]
Propranolol DM79NTF Angina pectoris BA40 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Capsaicin DMGMF6V Back pain ME84.Z Approved [121]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [122]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [124]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [125]
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Drug(s) Affected By Ephrin type-A receptor 7 (EPHA7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [126]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [127]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [128]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [69]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [69]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
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Drug(s) Affected By Bcl-2-like protein 11 (BCL2L11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [129]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Remdesivir DMBFZ6L Coronavirus Disease 2019 (COVID-19) 1D6Y Approved [132]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [133]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [134]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
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Drug(s) Affected By Tyrosine-protein kinase JAK2 (JAK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Momelotinib DMF98Q0 Myelofibrosis 2A20.2 Approved [136]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [36]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [138]
Estrone DM5T6US Acne vulgaris ED80 Approved [36]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [42]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [139]
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Drug(s) Affected By Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [140]
Gefitinib DM15F0X Colon adenocarcinoma Approved [141]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [142]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [143]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [144]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [145]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [146]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [147]
Selenium DM25CGV N. A. N. A. Approved [148]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [149]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [150]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [146]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Gefitinib DM15F0X Colon adenocarcinoma Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [51]
Selenium DM25CGV N. A. N. A. Approved [153]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [154]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [130]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [155]
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
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Drug(s) Affected By Prelamin-A/C (LMNA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [156]
Methotrexate DM2TEOL Anterior urethra cancer Approved [157]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [158]
Quercetin DM3NC4M Obesity 5B81 Approved [159]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [161]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [79]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [93]
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Drug(s) Affected By High affinity nerve growth factor receptor (NTRK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [163]
Folic Acid DMEMBJC Colorectal carcinoma Approved [45]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [165]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [167]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [168]
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Drug(s) Affected By Tyrosine-protein kinase Lck (LCK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [169]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [170]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [171]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [172]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [173]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [174]
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Drug(s) Affected By Tyrosine-protein kinase Fyn (FYN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [176]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ethanol DMDRQZU Chronic pain MG30 Approved [177]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [178]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [179]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [180]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Lyn (LYN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [170]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [181]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [93]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase HCK (HCK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [170]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [53]
Testosterone enanthate DMB6871 N. A. N. A. Approved [182]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [183]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [100]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [126]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [184]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Fgr (FGR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [170]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [185]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [186]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [187]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [100]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Poly polymerase 1 (PARP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [188]
Gefitinib DM15F0X Colon adenocarcinoma Approved [189]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [191]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [192]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [193]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [192]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [194]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [195]
Methotrexate DM2TEOL Anterior urethra cancer Approved [196]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [197]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [198]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [199]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [200]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [17]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [188]
Verapamil DMA7PEW Angina pectoris BA40 Approved [201]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [202]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [203]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mast/stem cell growth factor receptor Kit (KIT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [205]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [207]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [208]
Ethanol DMDRQZU Chronic pain MG30 Approved [209]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [210]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Breakpoint cluster region protein (BCR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [211]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [20]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [5]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [212]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Folic Acid DMEMBJC Colorectal carcinoma Approved [45]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [213]
Bortezomib DMNO38U Leukemia Approved [214]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [215]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [216]
Selenium DM25CGV N. A. N. A. Approved [153]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [217]
Methotrexate DM2TEOL Anterior urethra cancer Approved [157]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [218]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [219]
Quercetin DM3NC4M Obesity 5B81 Approved [211]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Troponin I, cardiac muscle (TNNI3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [221]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [222]
Perphenazine DMA4MRX Schizophrenia 6A20 Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [224]
Methamphetamine DMPM4SK Anxiety Approved [225]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [226]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ephrin type-A receptor 1 (EPHA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Testosterone DM7HUNW Hot flushes GA30 Approved [21]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Bortezomib DMNO38U Leukemia Approved [214]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [229]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase JAK1 (JAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [230]
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [231]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Clozapine DMFC71L Schizophrenia 6A20 Approved [233]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alanine aminotransferase 1 (GPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Halothane DM80OZ5 Anaesthesia 9A78.6 Approved [17]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [234]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [235]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [17]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [17]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [17]
Gefitinib DM15F0X Colon adenocarcinoma Approved [2]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [236]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [2]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [2]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [237]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [238]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [239]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [203]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [240]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [241]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [242]
Gefitinib DM15F0X Colon adenocarcinoma Approved [243]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [244]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [246]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [238]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [247]
Paclitaxel DMLB81S Breast carcinoma Approved [248]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [249]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [237]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [17]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [250]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [203]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ephrin type-A receptor 8 (EPHA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [46]
Arsenic DMTL2Y1 N. A. N. A. Approved [251]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [127]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [69]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [67]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Ephrin type-B receptor 2 (EPHB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [59]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [59]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Bortezomib DMNO38U Leukemia Approved [214]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [180]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [252]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [253]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [254]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [255]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [204]
Gefitinib DM15F0X Colon adenocarcinoma Approved [256]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [258]
Selenium DM25CGV N. A. N. A. Approved [156]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [259]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [154]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [260]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [206]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [228]
Gefitinib DM15F0X Colon adenocarcinoma Approved [261]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [262]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Etretinate DM2CZFA Keratosis ED56 Approved [264]
Prednisone DM2HG4X Acute asthma CA23 Approved [265]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [193]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [266]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase CSK (CSK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [267]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [93]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [126]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [268]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Signal transducer and activator of transcription 5A (STAT5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [270]
Testosterone DM7HUNW Hot flushes GA30 Approved [21]
Quizartinib DM8Y4JS Acute myeloid leukaemia 2A60 Approved [4]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [21]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [272]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [273]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [274]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [275]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [276]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [277]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [278]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [279]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [280]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase ABL2 (ABL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [282]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [64]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [252]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [126]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [283]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [64]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase FRK (FRK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [84]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [89]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [51]
Leflunomide DMR8ONJ Arthritis FA20 Approved [61]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [31]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [252]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Crk-like protein (CRKL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [22]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [284]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [93]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [285]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [286]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [287]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Rigosertib DMOSTXF Myelodysplastic syndrome 2A37 Phase 3 [288]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [289]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [290]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Blk (BLK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Menthol DMG2KW7 Back pain ME84.Z Approved [110]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
Bortezomib DMNO38U Leukemia Approved [214]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [291]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [292]
Rigosertib DMOSTXF Myelodysplastic syndrome 2A37 Phase 3 [293]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [294]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
SB-431542 DM0YOXQ Pulmonary fibrosis CB03.4 Preclinical [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytoplasmic tyrosine-protein kinase BMX (BMX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [296]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [297]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase JAK3 (JAK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [26]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Ceritinib DMB920Z Non-small-cell lung cancer 2C25.Y Approved [299]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [214]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [46]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [187]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [298]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [300]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ephrin type-B receptor 3 (EPHB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [301]
Clozapine DMFC71L Schizophrenia 6A20 Approved [78]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [302]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [97]
Urethane DM7NSI0 N. A. N. A. Phase 4 [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ephrin type-A receptor 5 (EPHA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [304]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [252]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [305]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [306]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [67]
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Drug(s) Affected By Ephrin type-B receptor 4 (EPHB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [44]
Testosterone enanthate DMB6871 N. A. N. A. Approved [182]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [175]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Omacetaxine mepesuccinate DMPU2WX Adult acute monocytic leukemia Approved [307]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [308]
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Drug(s) Affected By Ephrin type-B receptor 1 (EPHB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [309]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [127]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [310]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [67]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [79]
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Drug(s) Affected By Ephrin type-A receptor 4 (EPHA4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [36]
Epinephrine DM3KJBC Acute asthma CA23 Approved [311]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
Estrone DM5T6US Acne vulgaris ED80 Approved [36]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [91]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Mestranol DMG3F94 Contraception QA21 Approved [36]
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Drug(s) Affected By Cyclin-dependent kinase 6 (CDK6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [216]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [312]
Gefitinib DM15F0X Colon adenocarcinoma Approved [313]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [314]
Methotrexate DM2TEOL Anterior urethra cancer Approved [315]
Quercetin DM3NC4M Obesity 5B81 Approved [316]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [317]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Panobinostat DM58WKG Chronic graft versus host disease Approved [69]
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Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [203]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [318]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [319]
Methotrexate DM2TEOL Anterior urethra cancer Approved [320]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [321]
Quercetin DM3NC4M Obesity 5B81 Approved [98]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [322]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [318]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [323]
Ethacrynic acid DM60QMR Edema MG29 Approved [324]
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Drug(s) Affected By Protein-tyrosine kinase 6 (PTK6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Folic Acid DMEMBJC Colorectal carcinoma Approved [325]
Paclitaxel DMLB81S Breast carcinoma Approved [326]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [327]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [17]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [102]
Milchsaure DM462BT Pruritus EC90 Investigative [328]
eucalyptol DME5CK3 Discovery agent N.A. Investigative [329]
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Drug(s) Affected By Protein-tyrosine kinase 2-beta (PTK2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [330]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [49]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [331]
Ethanol DMDRQZU Chronic pain MG30 Approved [177]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [46]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [332]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [291]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Urethane DM7NSI0 N. A. N. A. Phase 4 [303]
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Drug(s) Affected By Receptor tyrosine-protein kinase erbB-4 (ERBB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [41]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [333]
Testosterone DM7HUNW Hot flushes GA30 Approved [86]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [334]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [335]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [336]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [337]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
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Drug(s) Affected By NT-3 growth factor receptor (NTRK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [162]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [39]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [23]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [338]
Arsenic DMTL2Y1 N. A. N. A. Approved [166]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [339]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [127]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [340]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BDNF/NT-3 growth factors receptor (NTRK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [341]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [342]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [28]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [343]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [344]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [62]
Heroin diacetylmorphine DMDBWHY Neurological disorder 6B60 Approved [345]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [346]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Discoidin domain-containing receptor 2 (DDR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [48]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [347]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [23]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [164]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [34]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [125]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [348]
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Drug(s) Affected By Microtubule-associated proteins 1A/1B light chain 3A (MAP1LC3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [349]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [350]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [351]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [352]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [40]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [93]
Capsaicin DMGMF6V Back pain ME84.Z Approved [353]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [32]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [354]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [88]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Fusion protein Bcr-Abl (Bcr-Abl) TTS7G69 BCR_HUMAN-ABL1_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
Alanine aminotransferase 1 (GPT) OTOXOA0Q ALAT1_HUMAN Protein Interaction/Cellular Processes [2]
Angiopoietin-1 receptor (TEK) OT78YN57 TIE2_HUMAN Gene/Protein Processing [3]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [4]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Gene/Protein Processing [4]
BDNF/NT-3 growth factors receptor (NTRK2) OTD557PU NTRK2_HUMAN Gene/Protein Processing [5]
Breakpoint cluster region protein (BCR) OTCN76C1 BCR_HUMAN Post-Translational Modifications [5]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Protein Interaction/Cellular Processes [6]
Crk-like protein (CRKL) OTOYSD1R CRKL_HUMAN Post-Translational Modifications [7]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Gene/Protein Processing [4]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Gene/Protein Processing [4]

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