Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMGBT68)

Drug Name
Chlorphrifos oxon Drug Info
Synonyms Diethyl 3,5,6-trichloropyridin-2-yl phosphate
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
21804
CAS Number
CAS 5598-15-2
TTD Drug ID
DMGBT68

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Fatty acid amide hydrolase (FAAH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [11]
Thiopental DMGP8AX Anaesthesia 9A78.6 Approved [12]
JNJ-42165279 DM72GZO Anxiety disorder 6B00-6B0Z Phase 2 [13]
SSR411298 DMGTB2Q Major depressive disorder 6A70.3 Phase 2 [14]
IW-6118 DMP42W1 Inflammation 1A00-CA43.1 Phase 2 [15]
PF-04457845 DMPRYU1 Liver disease DB90-BD99 Phase 2 [16]
IPI-940 DMEIM5G Pain MG30-MG3Z Phase 1 [17]
PMID29053063-Compound-11d DMDRK68 N. A. N. A. Patented [18]
Piperazine carbamic compound 1 DMZSYU4 N. A. N. A. Patented [18]
Piperazine carbamic compound 2 DMMQ0ZO N. A. N. A. Patented [18]
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Drug(s) Targeting Acetylcholinesterase (AChE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [19]
Donepezil DMIYG7Z Advanced cancer 2A00-2F9Z Approved [20]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [21]
Galantamine DMEO794 Alzheimer disease 8A20 Approved [22]
Huperzine A DMMAWLU Alzheimer disease 8A20 Approved [23]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [24]
YM443 DMNZCI1 Functional dyspepsia DD90.3 Approved [25]
Ambenonium DMOP0BL Myasthenia gravis 8C6Y Approved [26]
Demecarium bromide DMAYEU1 Open-angle glaucoma 9C61 Approved [27]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [28]
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Drug(s) Targeting Cannabinoid receptor 1 (CB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [29]
NABILONE DMVRYT2 Insomnia 7A00-7A0Z Approved [30]
Orlistat DMRJSP8 Obesity 5B81 Approved [31]
SR141716A DMCO5JZ Obesity 5B81 Approved [32]
Tebipenem DMVSX6O Urinary tract infection GC08 Phase 3 [33]
Conatumumab DM2UOSN Colorectal cancer 2B91.Z Phase 2 [34]
GW-42004 DMY3KSU Lipid metabolism disorder 5C52.Z Phase 2 [35]
SR-147778 DMNAECP Obesity 5B81 Phase 2 [36]
Nimacimab DM21Z68 Diabetic nephropathy GB61.Z Phase 2 [37]
AEF0117 DMQ1GH4 Marijuana use disorder 6C41 Phase 2 [38]
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Drug(s) Affected By Cholinesterase (BCHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [39]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [40]
Galantamine DMEO794 Alzheimer disease 8A20 Approved [41]
Rivastigmine DMG629M Alzheimer disease 8A20 Approved [42]
Donepezil DMIYG7Z Advanced cancer 2A00-2F9Z Approved [43]
Succinylcholine DM2ET1M Plasma cell myeloma 2A83.1 Approved [44]
Ethopropazine DM0N3L7 Parkinson disease 8A00.0 Approved [40]
Dimenhydrinate DM264B3 Meniere disease AB31.0 Approved [45]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [46]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [45]
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Drug(s) Affected By Acetylcholinesterase (ACHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [47]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [48]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [49]
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [51]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [49]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [52]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [53]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [54]
Testosterone DM7HUNW Hot flushes GA30 Approved [55]
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Drug(s) Affected By Fatty-acid amide hydrolase 1 (FAAH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [56]
Selenium DM25CGV N. A. N. A. Approved [57]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [58]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Arsenic DMTL2Y1 N. A. N. A. Approved [60]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [61]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [62]
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [63]
Amphetamine DMSZQAK Attention deficit hyperactivity disorder 6A05.Z Approved [64]
ASP-8477 DMBZQS7 Neuropathic pain 8E43.0 Phase 2 [65]
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Drug(s) Affected By 1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [57]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [55]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [70]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [71]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
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Drug(s) Affected By Transforming growth factor beta-1 proprotein (TGFB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [74]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [75]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [76]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [77]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [78]
Prednisone DM2HG4X Acute asthma CA23 Approved [79]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [80]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [81]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [83]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [84]
Fructose DM43AN2 Vomiting MD90 Approved [43]
Ketoprofen DMRKXPT Bursitis Approved [43]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [85]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [86]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [87]
Gefitinib DM15F0X Colon adenocarcinoma Approved [88]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [89]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [90]
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Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [91]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [92]
Gefitinib DM15F0X Colon adenocarcinoma Approved [93]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [94]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [96]
Selenium DM25CGV N. A. N. A. Approved [97]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [98]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [99]
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Drug(s) Affected By Serotransferrin (TF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [100]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [104]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [105]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [106]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [107]
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Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [108]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [109]
Gefitinib DM15F0X Colon adenocarcinoma Approved [110]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [111]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [112]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [115]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [111]
Estrone DM5T6US Acne vulgaris ED80 Approved [116]
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Drug(s) Affected By Platelet-derived growth factor subunit A (PDGFA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
Ramipril DM2R68E Acute heart failure BD10-BD13 Approved [117]
Methotrexate DM2TEOL Anterior urethra cancer Approved [118]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [119]
Panobinostat DM58WKG Chronic graft versus host disease Approved [120]
Estrone DM5T6US Acne vulgaris ED80 Approved [121]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [124]
Methotrexate DM2TEOL Anterior urethra cancer Approved [82]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [125]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [126]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [127]
Paclitaxel DMLB81S Breast carcinoma Approved [128]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [129]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [130]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [131]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [132]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [133]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [134]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [135]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [136]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [137]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Ethacrynic acid DM60QMR Edema MG29 Approved [139]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [140]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [141]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [142]
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Drug(s) Affected By Progesterone receptor (PGR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [143]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [144]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [145]
Estrone DM5T6US Acne vulgaris ED80 Approved [146]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [148]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [149]
Goserelin DMAT8CG Breast cancer 2C60-2C65 Approved [150]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [151]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [152]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [153]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [154]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [155]
Cepharanthine DM9Y5JB N. A. N. A. Approved [156]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [157]
Clozapine DMFC71L Schizophrenia 6A20 Approved [158]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [159]
Trifluoperazine DMKBYWI Anxiety Approved [160]
Olanzapine DMPFN6Y Bipolar depression Approved [158]
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Drug(s) Affected By Acylamino-acid-releasing enzyme (APEH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [57]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [161]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [162]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [70]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [163]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [164]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [165]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [69]
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Drug(s) Affected By Histidine decarboxylase (HDC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [166]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [167]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [169]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [169]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [7]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [120]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [7]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [170]
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Drug(s) Affected By Aromatic-L-amino-acid decarboxylase (DDC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [171]
Quercetin DM3NC4M Obesity 5B81 Approved [172]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [173]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [174]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [7]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [69]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [175]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [176]
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Drug(s) Affected By Protein-glutamine gamma-glutamyltransferase 2 (TGM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [177]
Etretinate DM2CZFA Keratosis ED56 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [179]
Testosterone DM7HUNW Hot flushes GA30 Approved [180]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [181]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [162]
Ethanol DMDRQZU Chronic pain MG30 Approved [182]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [183]
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Drug(s) Affected By Liver carboxylesterase 1 (CES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [184]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [185]
Dextropropoxyphene DM23HCX Pain MG30-MG3Z Approved [186]
Selenium DM25CGV N. A. N. A. Approved [57]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [187]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [189]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [190]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [192]
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Drug(s) Affected By Aryl hydrocarbon receptor (AHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [193]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [195]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [196]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [197]
Quercetin DM3NC4M Obesity 5B81 Approved [198]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [173]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [200]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
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Drug(s) Affected By DNA replication licensing factor MCM2 (MCM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [202]
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [204]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [205]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [180]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [180]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [207]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [162]
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Drug(s) Affected By Glutamate decarboxylase 2 (GAD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [7]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [161]
Arsenic DMTL2Y1 N. A. N. A. Approved [60]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [7]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [104]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [208]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [7]
CHLORPYRIFOS DMKPUI6 Discovery agent N.A. Investigative [7]
PARAOXON DMN4ZKC Discovery agent N.A. Investigative [7]
Hexadecanoic acid DMWUXDZ Discovery agent N.A. Investigative [209]
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Drug(s) Affected By Oxysterols receptor LXR-alpha (NR1H3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [210]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [211]
Gemfibrozil DMD8Q3J Hyperlipidaemia 5C80 Approved [212]
Ethanol DMDRQZU Chronic pain MG30 Approved [213]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [212]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [214]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [215]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [70]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [216]
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Drug(s) Affected By Peroxisomal acyl-coenzyme A oxidase 1 (ACOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Testosterone DM7HUNW Hot flushes GA30 Approved [55]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [211]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [162]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [217]
Ciprofibrate DMGC5DB Hyperlipoproteinemia 5C80 Approved [218]
Capsaicin DMGMF6V Back pain ME84.Z Approved [219]
Sodium Acetate Anhydrous DMH21E0 Hyponatraemia 5C72 Approved [220]
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Drug(s) Affected By Neutral cholesterol ester hydrolase 1 (NCEH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
Quercetin DM3NC4M Obesity 5B81 Approved [172]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [161]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [222]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [162]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Patatin-like phospholipase domain-containing protein 6 (PNPLA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [57]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [122]
Testosterone DM7HUNW Hot flushes GA30 Approved [55]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [224]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [224]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [225]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [59]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [70]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [226]
Arsenic DMTL2Y1 N. A. N. A. Approved [60]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate decarboxylase 1 (GAD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [172]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [227]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [228]
Panobinostat DM58WKG Chronic graft versus host disease Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [123]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [229]
Isoflurophate DMBSK7X Glaucoma/ocular hypertension 9C61 Approved [7]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [230]
Clozapine DMFC71L Schizophrenia 6A20 Approved [231]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [232]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [232]
Gefitinib DM15F0X Colon adenocarcinoma Approved [233]
Sunitinib DMCBJSR Acute undifferentiated leukemia Approved [43]
Rosuvastatin DMMIQ7G Arteriosclerosis BD40 Approved [234]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [235]
Methotrexate DM2TEOL Anterior urethra cancer Approved [236]
Quercetin DM3NC4M Obesity 5B81 Approved [237]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [238]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serum paraoxonase/arylesterase 1 (PON1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [240]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [241]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [242]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [243]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [244]
Quercetin DM3NC4M Obesity 5B81 Approved [245]
Panobinostat DM58WKG Chronic graft versus host disease Approved [120]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [246]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [201]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [247]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [248]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [249]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [250]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [251]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [252]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [253]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [254]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [255]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [257]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [258]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [259]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [260]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [261]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [261]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [262]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [263]
Capsaicin DMGMF6V Back pain ME84.Z Approved [264]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chromodomain-helicase-DNA-binding protein 8 (CHD8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [188]
Testosterone enanthate DMB6871 N. A. N. A. Approved [266]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [267]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [208]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [268]
Glyphosate DM0AFY7 Malaria 1F40-1F45 Investigative [269]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [268]
Milchsaure DM462BT Pruritus EC90 Investigative [270]
CHLORPYRIFOS DMKPUI6 Discovery agent N.A. Investigative [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [163]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [43]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [272]
Diazepam DM08E9O Alcohol withdrawal Approved [273]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [274]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [275]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [276]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [277]
Methotrexate DM2TEOL Anterior urethra cancer Approved [278]
Quercetin DM3NC4M Obesity 5B81 Approved [279]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Acetylcholinesterase (AChE) TT1RS9F ACES_HUMAN Inhibitor [2]
Cannabinoid receptor 1 (CB1) TT6OEDT CNR1_HUMAN Inhibitor [1]
Fatty acid amide hydrolase (FAAH) TTDP1UC NOUNIPROTAC Inhibitor [2]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) OT5I4Y9K PLCB_HUMAN Gene/Protein Processing [3]
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Gene/Protein Processing [4]
Acylamino-acid-releasing enzyme (APEH) OTX258QE ACPH_HUMAN Gene/Protein Processing [5]
Albumin (ALB) OTVMM513 ALBU_HUMAN Drug Response [6]
Aromatic-L-amino-acid decarboxylase (DDC) OT0TSW09 DDC_HUMAN Protein Interaction/Cellular Processes [7]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Gene/Protein Processing [8]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [9]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Gene/Protein Processing [3]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [10]
Cholinesterase (BCHE) OTOH3WQ9 CHLE_HUMAN Gene/Protein Processing [4]

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92 ERE-independent ERalpha target genes differentially expressed in human breast tumors. Mol Cell Endocrinol. 2005 Dec 21;245(1-2):53-9. doi: 10.1016/j.mce.2005.10.003. Epub 2005 Nov 17.
93 Reactive metabolite of gefitinib activates inflammasomes: implications for gefitinib-induced idiosyncratic reaction. J Toxicol Sci. 2020;45(11):673-680. doi: 10.2131/jts.45.673.
94 An in vitro coculture system of human peripheral blood mononuclear cells with hepatocellular carcinoma-derived cells for predicting drug-induced liver injury. Arch Toxicol. 2021 Jan;95(1):149-168. doi: 10.1007/s00204-020-02882-4. Epub 2020 Aug 20.
95 Gypenosides protect retinal pigment epithelium cells from oxidative stress. Food Chem Toxicol. 2018 Feb;112:76-85.
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