Details of the Drug Combination

General Information of Drug Combination (ID: DC9AEJU)

Drug Combination Name
Simvastatin Dexamethasone
Indication
Disease Entry Status REF
Lymphoma Phase 1 [1]
Component Drugs Simvastatin   DM30SGU Dexamethasone   DMMWZET
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Simvastatin
Disease Entry ICD 11 Status REF
Arteriosclerosis BD40 Approved [2]
Atherosclerosis BD40 Approved [2]
Coronary heart disease BA80.Z Approved [2]
Cystic fibrosis CA25 Approved [2]
Depression 6A70-6A7Z Approved [2]
Hypercholesterolaemia 5C80.0 Approved [3]
Hyperlipidemia 5C80.Z Approved [2]
Hyperlipidemia, familial combined, LPL related N.A. Approved [2]
Hypertriglyceridemia 5C80.1 Approved [2]
Pneumonia CA40 Approved [2]
Primary hypercholesterolemia 5C80.00 Approved [2]
Prostate carcinoma N.A. Approved [2]
Rhinitis FA20 Approved [2]
Type-1/2 diabetes 5A10-5A11 Approved [2]
Stroke 8B20 Investigative [2]
Simvastatin Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
HMG-CoA reductase (HMGCR) TTPADOQ HMDH_HUMAN Inhibitor [10]
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Simvastatin Interacts with 3 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [11]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [12]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [13]
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Simvastatin Interacts with 8 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [14]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Metabolism [15]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Metabolism [16]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Metabolism [17]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Metabolism [18]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Metabolism [15]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DEB3CV1 UD2B7_HUMAN Metabolism [15]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DEF2WXN UD13_HUMAN Metabolism [15]
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⏷ Show the Full List of 8 DME(s)
Simvastatin Interacts with 264 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Decreases Activity [19]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Increases Expression [20]
Cytochrome P450 3A5 (CYP3A5) OTSXFBXB CP3A5_HUMAN Affects Response To Substance [21]
Solute carrier organic anion transporter family member 1B1 (SLCO1B1) OTNEN8QK SO1B1_HUMAN Increases Response To Substance [22]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Transport [23]
Stromelysin-1 (MMP3) OTGBI74Z MMP3_HUMAN Increases ADR [24]
Apolipoprotein E (APOE) OTFOWL2H APOE_HUMAN Increases Response To Substance [25]
3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) OTRT3F3U HMDH_HUMAN Decreases Response To Substance [26]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Decreases Activity [23]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Activity [27]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Increases Expression [27]
Nuclear receptor subfamily 1 group I member 3 (NR1I3) OTS3SGH7 NR1I3_HUMAN Increases Activity [27]
Prostaglandin E synthase (PTGES) OTB7YQFU PTGES_HUMAN Decreases Expression [28]
Myeloperoxidase (MPO) OTOOXLIN PERM_HUMAN Decreases Expression [28]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Decreases Activity [28]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Decreases Expression [28]
Advanced glycosylation end product-specific receptor (AGER) OTPY0IH7 RAGE_HUMAN Decreases Expression [28]
CCN family member 1 (CCN1) OTKJBEMD CCN1_HUMAN Decreases Expression [7]
Aurora kinase A (AURKA) OTMX0HYT AURKA_HUMAN Decreases Expression [7]
Cell division control protein 45 homolog (CDC45) OT6NNLOD CDC45_HUMAN Decreases Expression [7]
Integrin beta-like protein 1 (ITGBL1) OTJDHE17 ITGBL_HUMAN Decreases Expression [7]
Protein S100-A8 (S100A8) OTVMOB3F S10A8_HUMAN Increases Expression [7]
Integrin beta-1 (ITGB1) OT6G1IAR ITB1_HUMAN Decreases Expression [7]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Decreases Expression [7]
Protein S100-A9 (S100A9) OTOARHCS S10A9_HUMAN Increases Expression [7]
Protein S100-A6 (S100A6) OTHHPZQ8 S10A6_HUMAN Increases Expression [7]
Thrombospondin-1 (THBS1) OT0ECWK3 TSP1_HUMAN Decreases Expression [7]
Stromelysin-2 (MMP10) OTJDWW8Q MMP10_HUMAN Increases Expression [7]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Decreases Expression [7]
Annexin A3 (ANXA3) OTDD8OI7 ANXA3_HUMAN Decreases Expression [7]
Keratin, type I cytoskeletal 13 (KRT13) OTTYSKGX K1C13_HUMAN Increases Expression [7]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 (PLCG2) OTGVC9MY PLCG2_HUMAN Increases Expression [7]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [7]
Keratin, type I cytoskeletal 15 (KRT15) OTS6WLF7 K1C15_HUMAN Increases Expression [7]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Decreases Expression [7]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [7]
Insulin-like growth factor-binding protein 6 (IGFBP6) OTW878VI IBP6_HUMAN Increases Expression [7]
Calmodulin-like protein 3 (CALML3) OTM8DNQU CALL3_HUMAN Increases Expression [7]
Gap junction beta-2 protein (GJB2) OTBKLEYB CXB2_HUMAN Increases Expression [7]
Tyrosine-protein kinase receptor UFO (AXL) OTKA2SUX UFO_HUMAN Decreases Expression [7]
Aldehyde dehydrogenase, dimeric NADP-preferring (ALDH3A1) OTAYZZE6 AL3A1_HUMAN Increases Expression [7]
DNA replication licensing factor MCM4 (MCM4) OT19PNNG MCM4_HUMAN Decreases Expression [7]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [7]
Macrophage metalloelastase (MMP12) OT9Z7LHM MMP12_HUMAN Increases Expression [7]
Replication factor C subunit 5 (RFC5) OTAD79RT RFC5_HUMAN Decreases Expression [7]
Regulator of G-protein signaling 2 (RGS2) OT0FSRW7 RGS2_HUMAN Increases Expression [7]
Collagenase 3 (MMP13) OTY8BZIE MMP13_HUMAN Increases Expression [7]
DNA primase small subunit (PRIM1) OTWWP8Y6 PRI1_HUMAN Decreases Expression [7]
Cyclin-dependent kinase inhibitor 1C (CDKN1C) OTASTJ3Q CDN1C_HUMAN Increases Expression [7]
Transcription factor E2F1 (E2F1) OTLKYBBC E2F1_HUMAN Decreases Expression [7]
Collagen alpha-1(VII) chain (COL7A1) OT3MIRZJ CO7A1_HUMAN Increases Expression [7]
Keratin, type I cytoskeletal 17 (KRT17) OT6Y1DPK K1C17_HUMAN Increases Expression [7]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Increases Expression [7]
Focal adhesion kinase 1 (PTK2) OT3Q1JDY FAK1_HUMAN Decreases Activity [7]
Lymphotoxin-beta (LTB) OTUFS8CF TNFC_HUMAN Decreases Expression [7]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Increases Expression [7]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1) OTXNGZCG MD2L1_HUMAN Decreases Expression [7]
Centromere protein R (ITGB3BP) OT6Q7GR3 CENPR_HUMAN Decreases Expression [7]
Rho GTPase-activating protein 29 (ARHGAP29) OT8JH4TY RHG29_HUMAN Decreases Expression [7]
Interleukin-20 receptor subunit beta (IL20RB) OTHFXK95 I20RB_HUMAN Increases Expression [7]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [7]
Krueppel-like factor 6 (KLF6) OTQY9S7F KLF6_HUMAN Increases Expression [7]
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase (PKMYT1) OTYRXD2T PMYT1_HUMAN Decreases Expression [7]
Cell division control protein 6 homolog (CDC6) OTX93FE7 CDC6_HUMAN Decreases Expression [7]
Spondin-2 (SPON2) OTE7JLNM SPON2_HUMAN Increases Expression [7]
Rac GTPase-activating protein 1 (RACGAP1) OTQE8IEH RGAP1_HUMAN Decreases Expression [7]
DNA replication factor Cdt1 (CDT1) OTVY53VG CDT1_HUMAN Decreases Expression [7]
Matrix metalloproteinase-28 (MMP28) OTHQZXM1 MMP28_HUMAN Increases Expression [7]
Alpha-catulin (CTNNAL1) OTESJ6JD CTNL1_HUMAN Decreases Expression [7]
Protein DBF4 homolog A (DBF4) OTBL7JHQ DBF4A_HUMAN Decreases Expression [7]
Krueppel-like factor 2 (KLF2) OTIP1UFX KLF2_HUMAN Increases Expression [7]
Catalase (CAT) OTHEBX9R CATA_HUMAN Increases Activity [29]
Sterol regulatory element-binding protein 1 (SREBF1) OTWBRPAI SRBP1_HUMAN Increases Localization [30]
NPC1-like intracellular cholesterol transporter 1 (NPC1L1) OT6GWW1P NPCL1_HUMAN Decreases Expression [31]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Increases Expression [32]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Decreases Expression [32]
Killer cell immunoglobulin-like receptor 2DS2 (KIR2DS2) OTX31RLZ KI2S2_HUMAN Decreases Expression [32]
Killer cell lectin-like receptor subfamily F member 1 (KLRF1) OTGHZ7FU KLRF1_HUMAN Decreases Expression [32]
Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK) OTLF4ZB1 IKKA_HUMAN Increases Phosphorylation [33]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Nitrosation [33]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Increases Phosphorylation [33]
Methylenetetrahydrofolate reductase (MTHFR) OTUBJSR7 MTHR_HUMAN Increases Expression [34]
Sphingosine 1-phosphate receptor 1 (S1PR1) OTLTXDQT S1PR1_HUMAN Increases Expression [35]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Increases Expression [36]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Decreases Activity [37]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Decreases Secretion [38]
Delta(24)-sterol reductase (DHCR24) OTP301JW DHC24_HUMAN Increases Expression [39]
Farnesyl pyrophosphate synthase (FDPS) OT6CKWV5 FPPS_HUMAN Increases Expression [40]
Squalene synthase (FDFT1) OTGDISIT FDFT_HUMAN Increases Expression [40]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Increases Expression [41]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Increases Expression [41]
Toll-like receptor 4 (TLR4) OTP7ML3S TLR4_HUMAN Increases Expression [42]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) OTQ4W7MT TR11B_HUMAN Increases Expression [43]
Dynamin-1-like protein (DNM1L) OTXK1Q1G DNM1L_HUMAN Increases Expression [44]
Suppressor of cytokine signaling 7 (SOCS7) OT503VJG SOCS7_HUMAN Increases Expression [45]
Suppressor of cytokine signaling 3 (SOCS3) OTY183WJ SOCS3_HUMAN Increases Expression [45]
Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) OT9RDS3H IKKB_HUMAN Decreases Expression [46]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [47]
Transmembrane protease serine 2 (TMPRSS2) OTN44YQ5 TMPS2_HUMAN Increases Expression [48]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Decreases Expression [49]
Serine protease HTRA2, mitochondrial (HTRA2) OTC7616F HTRA2_HUMAN Affects Localization [44]
Alpha-actinin-4 (ACTN4) OTCNZAJ5 ACTN4_HUMAN Increases Expression [50]
E3 ubiquitin-protein ligase MARCHF6 (MARCHF6) OTBTA03N MARH6_HUMAN Increases Degradation [51]
Nephrin (NPHS1) OT21JD3P NPHN_HUMAN Increases Expression [50]
Toll-like receptor 2 (TLR2) OTGO5P4R TLR2_HUMAN Increases Expression [42]
Apolipoprotein M (APOM) OTI3FQQC APOM_HUMAN Decreases Expression [52]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Decreases Expression [53]
Prothrombin (F2) OTNFSM49 THRB_HUMAN Decreases Activity [54]
Tissue-type plasminogen activator (PLAT) OTQPDNAB TPA_HUMAN Increases Expression [55]
Angiotensinogen (AGT) OTBZLYR3 ANGT_HUMAN Decreases Expression [56]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Decreases Expression [57]
GTPase KRas (KRAS) OT78QCN8 RASK_HUMAN Decreases Prenylation [58]
Platelet-derived growth factor subunit B (PDGFB) OTMFMFC3 PDGFB_HUMAN Decreases Activity [59]
Low-density lipoprotein receptor (LDLR) OTH559LU LDLR_HUMAN Increases Expression [60]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Decreases Activity [61]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Increases Expression [45]
Interleukin-2 receptor subunit alpha (IL2RA) OT0MWCHG IL2RA_HUMAN Decreases Expression [45]
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1) OTVVI3UI DQB1_HUMAN Affects Expression [62]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Decreases Expression [63]
Collagen alpha-1(III) chain (COL3A1) OTT1EMLM CO3A1_HUMAN Increases Expression [64]
Apolipoprotein A-I (APOA1) OT5THARI APOA1_HUMAN Increases Expression [65]
C-reactive protein (CRP) OT0RFT8F CRP_HUMAN Decreases Expression [66]
Alpha-fetoprotein (AFP) OT9GG3ZI FETA_HUMAN Increases Expression [67]
Transferrin receptor protein 1 (TFRC) OT8ZPBDL TFR1_HUMAN Affects Expression [42]
Osteocalcin (BGLAP) OTK1YLWQ OSTCN_HUMAN Increases Expression [68]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Decreases Secretion [69]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Decreases Activity [70]
Apolipoprotein B-100 (APOB) OTH0UOCZ APOB_HUMAN Decreases Expression [71]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Increases Expression [72]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Decreases Activity [73]
Amyloid-beta precursor protein (APP) OTKFD7R4 A4_HUMAN Decreases Activity [74]
Integrin beta-2 (ITGB2) OTEKPEPR ITB2_HUMAN Decreases Expression [75]
Interleukin-4 (IL4) OTOXBWAU IL4_HUMAN Increases Expression [45]
Plasminogen activator inhibitor 1 (SERPINE1) OTT0MPQ3 PAI1_HUMAN Decreases Expression [76]
Alkaline phosphatase, tissue-nonspecific isozyme (ALPL) OTG7J4BP PPBT_HUMAN Affects Expression [77]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Decreases Expression [78]
Endothelin-1 (EDN1) OTZCACEG EDN1_HUMAN Decreases Expression [79]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Decreases Expression [75]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Decreases Localization [80]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Decreases Phosphorylation [81]
Thrombomodulin (THBD) OT8VHLKY TRBM_HUMAN Increases Expression [54]
Calpain-1 catalytic subunit (CAPN1) OTK6OQZR CAN1_HUMAN Increases Expression [82]
Heat shock protein HSP 90-alpha (HSP90AA1) OTLG1WPK HS90A_HUMAN Increases Expression [83]
Insulin-like growth factor 1 receptor (IGF1R) OTXJIF13 IGF1R_HUMAN Decreases Expression [84]
Rho-related GTP-binding protein RhoC (RHOC) OTOLE1FT RHOC_HUMAN Increases Expression [54]
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Decreases Activity [85]
Fibroblast growth factor 2 (FGF2) OT7YUJ9F FGF2_HUMAN Increases Expression [86]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [87]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [44]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Decreases Expression [78]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [88]
Osteopontin (SPP1) OTJGC23Y OSTP_HUMAN Decreases Expression [89]
Microtubule-associated protein tau (MAPT) OTMTP2Z7 TAU_HUMAN Affects Expression [90]
Endoplasmic reticulum chaperone BiP (HSPA5) OTFUIRAO BIP_HUMAN Increases Expression [82]
Cholesteryl ester transfer protein (CETP) OTAGPPOE CETP_HUMAN Decreases Expression [91]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Decreases Expression [92]
Bone morphogenetic protein 2 (BMP2) OT23T37S BMP2_HUMAN Increases Expression [93]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Decreases Expression [78]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Decreases Expression [94]
Tissue factor (F3) OT3MSU3B TF_HUMAN Decreases Expression [95]
HLA class I histocompatibility antigen, alpha chain E (HLA-E) OTX1CTFB HLAE_HUMAN Affects Expression [62]
Matrix metalloproteinase-9 (MMP9) OTB2QDAV MMP9_HUMAN Decreases Activity [96]
Indoleamine 2,3-dioxygenase 1 (IDO1) OT91DBN7 I23O1_HUMAN Increases Expression [97]
Ras-related C3 botulinum toxin substrate 2 (RAC2) OTAOHFNH RAC2_HUMAN Affects Localization [44]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Decreases Expression [72]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Phosphorylation [98]
Integrin beta-4 (ITGB4) OT28UK84 ITB4_HUMAN Increases Expression [54]
Cytotoxic T-lymphocyte protein 4 (CTLA4) OTYQR611 CTLA4_HUMAN Decreases Expression [45]
E-selectin (SELE) OT33RZWY LYAM2_HUMAN Decreases Expression [99]
Arachidonate 5-lipoxygenase-activating protein (ALOX5AP) OT0DH40W AL5AP_HUMAN Increases Expression [64]
Integrin alpha-L (ITGAL) OTCUQAIS ITAL_HUMAN Decreases Expression [75]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Increases Expression [97]
Tumor necrosis factor ligand superfamily member 4 (TNFSF4) OTOCBX7P TNFL4_HUMAN Decreases Expression [100]
Interleukin-4 receptor subunit alpha (IL4R) OTTXOTCW IL4RA_HUMAN Decreases Expression [45]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Decreases Expression [92]
Tumor necrosis factor receptor superfamily member 5 (CD40) OT5YU2XB TNR5_HUMAN Decreases Expression [42]
CD27 antigen (CD27) OTH7NA58 CD27_HUMAN Decreases Expression [45]
Serum paraoxonase/arylesterase 1 (PON1) OTD0Z2XO PON1_HUMAN Increases Expression [101]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Activity [70]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Activity [70]
Nitric oxide synthase 3 (NOS3) OTLDT7NR NOS3_HUMAN Increases Expression [102]
M-phase inducer phosphatase 2 (CDC25B) OT12MSRY MPIP2_HUMAN Affects Expression [103]
HLA class I histocompatibility antigen, alpha chain F (HLA-F) OT76CM19 HLAF_HUMAN Affects Expression [62]
Type-1 angiotensin II receptor (AGTR1) OT2NRMJP AGTR1_HUMAN Decreases Expression [104]
Sodium-dependent serotonin transporter (SLC6A4) OT6FGDLW SC6A4_HUMAN Increases Activity [105]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Expression [106]
Heat shock 70 kDa protein 4 (HSPA4) OT5HR0AR HSP74_HUMAN Increases Expression [83]
Nitric oxide synthase, inducible (NOS2) OTKKIOJ1 NOS2_HUMAN Increases Expression [107]
Myosin-10 (MYH10) OTXN2WXS MYH10_HUMAN Decreases Expression [57]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Decreases Activity [108]
C-C chemokine receptor type 2 (CCR2) OTQ7T10J CCR2_HUMAN Decreases Expression [109]
T-lymphocyte activation antigen CD86 (CD86) OTJCSBPC CD86_HUMAN Decreases Expression [42]
Signal transducer and activator of transcription 1-alpha/beta (STAT1) OTLMBUZ6 STAT1_HUMAN Decreases Expression [110]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Expression [111]
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) OTDK74C0 TNR4_HUMAN Decreases Expression [100]
ATP-binding cassette sub-family G member 1 (ABCG1) OT5BG6MK ABCG1_HUMAN Decreases Expression [53]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [112]
CX3C chemokine receptor 1 (CX3CR1) OTIM9XT8 CX3C1_HUMAN Decreases Expression [113]
Fatty acid synthase (FASN) OTFII9KG FAS_HUMAN Increases Expression [114]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Increases Expression [90]
Nuclear receptor ROR-gamma (RORC) OTUBFRPC RORG_HUMAN Decreases Expression [45]
C-C chemokine receptor type 5 (CCR5) OTP5FMZ4 CCR5_HUMAN Decreases Expression [94]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Activity [115]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Decreases Activity [116]
Cyclin-dependent kinase 4 inhibitor D (CDKN2D) OT2TTZPZ CDN2D_HUMAN Increases Expression [92]
Ras-related C3 botulinum toxin substrate 3 (RAC3) OT2RE7A7 RAC3_HUMAN Affects Localization [44]
Transforming protein RhoA (RHOA) OT6YOJ9N RHOA_HUMAN Increases Expression [54]
Ras-related protein Rap-1A (RAP1A) OT5RH6TI RAP1A_HUMAN Decreases Expression [117]
Ras-related C3 botulinum toxin substrate 1 (RAC1) OTKRO61U RAC1_HUMAN Decreases Activity [70]
Rho GTPase-activating protein 4 (ARHGAP4) OTXV053R RHG04_HUMAN Increases Expression [54]
Cyclin-dependent kinase 5 (CDK5) OT1YAK9F CDK5_HUMAN Increases Expression [90]
Heat shock factor protein 1 (HSF1) OTYNJ4KP HSF1_HUMAN Affects Localization [83]
E3 ubiquitin-protein ligase Mdm2 (MDM2) OTOVXARF MDM2_HUMAN Increases Phosphorylation [118]
CD83 antigen (CD83) OT1V4WQF CD83_HUMAN Decreases Expression [42]
Myosin light chain 5 (MYL5) OT7CQ24K MYL5_HUMAN Increases Expression [64]
Caldesmon (CALD1) OTNJKJ6Q CALD1_HUMAN Decreases Expression [54]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [88]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Decreases Expression [49]
Sterol regulatory element-binding protein 2 (SREBF2) OTBXUNPL SRBP2_HUMAN Increases Expression [119]
Forkhead box protein O1 (FOXO1) OTPJRB6D FOXO1_HUMAN Decreases Localization [116]
TNF receptor-associated factor 2 (TRAF2) OT1MEZZN TRAF2_HUMAN Decreases Expression [46]
Nuclear factor of activated T-cells, cytoplasmic 3 (NFATC3) OTYOORME NFAC3_HUMAN Decreases Localization [120]
Myosin-binding protein H (MYBPH) OTQJBPUR MYBPH_HUMAN Increases Expression [64]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Decreases Expression [49]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Increases Expression [44]
Bone morphogenetic protein receptor type-2 (BMPR2) OTM9W547 BMPR2_HUMAN Increases Stability [121]
Runt-related transcription factor 2 (RUNX2) OT97RQQM RUNX2_HUMAN Increases Expression [86]
Src substrate cortactin (CTTN) OTJRG4ES SRC8_HUMAN Affects Localization [54]
Squalene monooxygenase (SQLE) OT0GGRDO ERG1_HUMAN Decreases Degradation [51]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Activity [122]
Interferon regulatory factor 4 (IRF4) OT1DHQ1P IRF4_HUMAN Decreases Expression [123]
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TRADD) OTBOSJHO TRADD_HUMAN Decreases Expression [46]
Interleukin-17A (IL17A) OTY72FT2 IL17_HUMAN Decreases Expression [45]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Increases Expression [8]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Decreases Activity [73]
Interleukin-27 subunit alpha (IL27) OTIS3OF8 IL27A_HUMAN Increases Expression [45]
Scavenger receptor class B member 1 (SCARB1) OTAE1UA1 SCRB1_HUMAN Increases Expression [124]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Decreases Phosphorylation [116]
Rho guanine nucleotide exchange factor 2 (ARHGEF2) OTBQTFRT ARHG2_HUMAN Increases Expression [54]
Interleukin-17F (IL17F) OT9W9DE0 IL17F_HUMAN Decreases Secretion [123]
Sphingosine 1-phosphate receptor 3 (S1PR3) OTXBIYO8 S1PR3_HUMAN Decreases Expression [124]
Mitogen-activated protein kinase kinase kinase 14 (MAP3K14) OTT3DOOL M3K14_HUMAN Decreases Expression [46]
Angiotensin-converting enzyme 2 (ACE2) OTTRZGU7 ACE2_HUMAN Decreases Expression [48]
Forkhead box protein P3 (FOXP3) OTA9Z9OC FOXP3_HUMAN Increases Expression [97]
Interleukin-22 (IL22) OTW31FU9 IL22_HUMAN Decreases Secretion [123]
Interleukin-21 (IL21) OTABCY4W IL21_HUMAN Decreases Expression [45]
Podocin (NPHS2) OTLCNUII PODO_HUMAN Increases Expression [50]
Interleukin-23 subunit alpha (IL23A) OTYO99HC IL23A_HUMAN Decreases Expression [45]
Diablo IAP-binding mitochondrial protein (DIABLO) OTHJ9MCZ DBLOH_HUMAN Affects Localization [44]
Dentin sialophosphoprotein (DSPP) OT1TYNDN DSPP_HUMAN Increases Expression [125]
7-dehydrocholesterol reductase (DHCR7) OTLILBUI DHCR7_HUMAN Affects Expression [77]
CD2-associated protein (CD2AP) OTC76KQM CD2AP_HUMAN Increases Expression [50]
Cytochrome b-245 light chain (CYBA) OT16N9ZO CY24A_HUMAN Affects Response To Substance [126]
5-hydroxytryptamine receptor 7 (HTR7) OT44DEWB 5HT7R_HUMAN Increases Response To Substance [127]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Increases Response To Substance [38]
Leptin receptor (LEPR) OT9H7G0C LEPR_HUMAN Affects Response To Substance [128]
Liver carboxylesterase 1 (CES1) OT9L0LR8 EST1_HUMAN Increases ADR [24]
Small ribosomal subunit protein mS31 (MRPS31) OTB0OBWK RT31_HUMAN Decreases Response To Substance [129]
Neuropilin-1 (NRP1) OTCGULYV NRP1_HUMAN Decreases Response To Substance [129]
Sterol regulatory element-binding protein cleavage-activating protein (SCAP) OTCVXOD6 SCAP_HUMAN Affects Response To Substance [130]
Kinesin-like protein KIF6 (KIF6) OTDH3MR4 KIF6_HUMAN Increases ADR [131]
Collagen alpha-1(XIII) chain (COL13A1) OTM9IM6J CODA1_HUMAN Decreases Response To Substance [129]
5-hydroxytryptamine receptor 3B (HTR3B) OTMGIYRE 5HT3B_HUMAN Increases Response To Substance [127]
ELL-associated factor 2 (EAF2) OTSOET5L EAF2_HUMAN Decreases Response To Substance [129]
------------------------------------------------------------------------------------
⏷ Show the Full List of 264 DOT(s)
Indication(s) of Dexamethasone
Disease Entry ICD 11 Status REF
Acute adrenal insufficiency N.A. Approved [4]
Acute asthma CA23 Approved [4]
Addison disease 5A74.0 Approved [4]
Allergic otitis media N.A. Approved [4]
Allergic rhinitis CA08.0 Approved [4]
Angioedema 4A00.15 Approved [4]
Articular cartilage disorder FA34.Y Approved [4]
Autoimmune haemolytic anaemia 3A20 Approved [4]
Blepharoconjunctivitis N.A. Approved [4]
Burkitt lymphoma N.A. Approved [4]
Bursitis N.A. Approved [4]
Central retinal vein occlusion with macular edema N.A. Approved [4]
Cerebral edema 8D60.1 Approved [4]
Congenital adrenal hyperplasia 5A71.01 Approved [4]
Corneal abrasion NA06.4 Approved [4]
Corneal ulcer 9A76 Approved [4]
Crohn disease DD70 Approved [4]
Dermatitis herpetiformis EB44 Approved [4]
Diamond-Blackfan anemia N.A. Approved [4]
Disorder of orbital region N.A. Approved [4]
Epicondylitis N.A. Approved [4]
Erythema multiforme N.A. Approved [4]
Exanthem N.A. Approved [4]
Granuloma annulare N.A. Approved [4]
Inflammatory bowel disease DD72 Approved [4]
Keratitis N.A. Approved [4]
Liver cirrhosis DB93.1 Approved [4]
Lung cancer 2C25.0 Approved [4]
Malignant otitis externa caused by Pseudomonas aeruginosa N.A. Approved [4]
Miliary tuberculosis N.A. Approved [4]
Multiple sclerosis 8A40 Approved [4]
Mycosis fungoides 2B01 Approved [4]
Nausea MD90 Approved [4]
Plasma cell myeloma 2A83.1 Approved [4]
Primary cutaneous T-cell lymphoma N.A. Approved [4]
Psoriasis EA90 Approved [4]
Psoriatic arthritis FA21 Approved [4]
Rheumatic heart disease N.A. Approved [4]
Rheumatoid arthritis FA20 Approved [5]
Rosacea ED90.0 Approved [4]
Sarcoidosis 4B20.5 Approved [4]
Serum sickness N.A. Approved [4]
Skin disease EA00-EM0Z Approved [4]
Systemic lupus erythematosus 4A40.0 Approved [4]
Vomiting MD90 Approved [4]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2/3 [6]
Acquired thrombocytopenia N.A. Investigative [4]
Asthma CA23 Investigative [4]
B-cell neoplasm N.A. Investigative [4]
Beta-thalassemia major N.A. Investigative [4]
Classic Hodgkin lymphoma N.A. Investigative [4]
Follicular lymphoma 2A80 Investigative [4]
Iridocyclitis N.A. Investigative [4]
Keloid EE60 Investigative [4]
Trichinellosis N.A. Investigative [4]
Uveitis 9A96.Z Investigative [4]
Dexamethasone Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Glucocorticoid receptor (NR3C1) TTYRL6O GCR_HUMAN Agonist [141]
------------------------------------------------------------------------------------
Dexamethasone Interacts with 2 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [142]
Peptide transporter 1 (SLC15A1) DT9G7XN S15A1_HUMAN Substrate [143]
------------------------------------------------------------------------------------
Dexamethasone Interacts with 5 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [144]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Metabolism [145]
Cytochrome P450 3A7 (CYP3A7) DERD86B CP3A7_HUMAN Metabolism [146]
Carboxylesterase 2 (CES2) DETHCPD EST2_HUMAN Metabolism [147]
Corticosteroid 11-beta-dehydrogenase 2 (HSD11B2) DEDH7FP DHI2_HUMAN Metabolism [148]
------------------------------------------------------------------------------------
Dexamethasone Interacts with 979 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Increases Expression [149]
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Increases Expression [150]
Cytochrome P450 3A5 (CYP3A5) OTSXFBXB CP3A5_HUMAN Increases Expression [151]
Cytochrome P450 3A7 (CYP3A7) OTTCDHHM CP3A7_HUMAN Increases Expression [152]
Cocaine esterase (CES2) OTC647SQ EST2_HUMAN Increases Expression [153]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [154]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Increases Expression [134]
Haptoglobin (HP) OTGUGAF9 HPT_HUMAN Increases Expression [134]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [134]
Thrombomodulin (THBD) OT8VHLKY TRBM_HUMAN Decreases Expression [135]
Interleukin-4 (IL4) OTOXBWAU IL4_HUMAN Decreases Expression [155]
Solute carrier family 2, facilitated glucose transporter member 4 (SLC2A4) OTJZG0LD GLUT4_HUMAN Affects Expression [156]
Ribosomal protein S6 kinase beta-1 (RPS6KB1) OTAELNGX KS6B1_HUMAN Decreases Phosphorylation [157]
TSC22 domain family protein 3 (TSC22D3) OT03UM03 T22D3_HUMAN Increases Expression [158]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Increases ADR [24]
C-Jun-amino-terminal kinase-interacting protein 1 (MAPK8IP1) OTDAWAUZ JIP1_HUMAN Increases ADR [24]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Increases Response To Substance [159]
Endothelin-1 (EDN1) OTZCACEG EDN1_HUMAN Decreases Expression [160]
Nitric oxide synthase, inducible (NOS2) OTKKIOJ1 NOS2_HUMAN Decreases Expression [160]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Increases Expression [132]
Gasdermin-E (GSDME) OT1ZWY32 GSDME_HUMAN Increases Expression [132]
Protein arginine N-methyltransferase 3 (PRMT3) OTH2KILE ANM3_HUMAN Decreases Expression [132]
GRB2-related adapter protein 2 (GRAP2) OTS5NIZ3 GRAP2_HUMAN Increases Expression [132]
AP-1 complex subunit gamma-like 2 (AP1G2) OTTJ7NXL AP1G2_HUMAN Increases Expression [132]
Cell cycle checkpoint protein RAD17 (RAD17) OT1I93DT RAD17_HUMAN Decreases Expression [132]
Endonuclease domain-containing 1 protein (ENDOD1) OTME0ZW5 ENDD1_HUMAN Decreases Expression [132]
Rho-related BTB domain-containing protein 3 (RHOBTB3) OT1BFKPH RHBT3_HUMAN Increases Expression [132]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [132]
Serglycin (SRGN) OTFAVSX0 SRGN_HUMAN Increases Expression [132]
Integrin alpha-4 (ITGA4) OTSCAL0V ITA4_HUMAN Decreases Expression [132]
V(D)J recombination-activating protein 1 (RAG1) OTV131E4 RAG1_HUMAN Decreases Expression [132]
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform (PPP3CB) OTEGNEHW PP2BB_HUMAN Decreases Expression [132]
Interleukin-7 receptor subunit alpha (IL7R) OTBMFLQQ IL7RA_HUMAN Increases Expression [132]
Leukocyte surface antigen CD53 (CD53) OT9U5OXJ CD53_HUMAN Increases Expression [132]
Receptor-type tyrosine-protein phosphatase mu (PTPRM) OTCEL6PN PTPRM_HUMAN Increases Expression [132]
Inositol polyphosphate 1-phosphatase (INPP1) OTHSJCRQ INPP_HUMAN Increases Expression [132]
C-C chemokine receptor type 4 (CCR4) OT68KZ9B CCR4_HUMAN Increases Expression [132]
Calcipressin-1 (RCAN1) OT1MVXC7 RCAN1_HUMAN Increases Expression [132]
Protein BTG1 (BTG1) OTVJ2CDM BTG1_HUMAN Increases Expression [132]
Protein BTG2 (BTG2) OTZF6K1H BTG2_HUMAN Increases Expression [132]
Microtubule-associated protein 1A (MAP1A) OTHO8K43 MAP1A_HUMAN Increases Expression [132]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) OTCO26FV HMCS1_HUMAN Decreases Expression [132]
Transducin-like enhancer protein 4 (TLE4) OT4QEH6T TLE4_HUMAN Decreases Expression [132]
Synaptic vesicular amine transporter (SLC18A2) OTUOMMM6 VMAT2_HUMAN Increases Expression [132]
Amidophosphoribosyltransferase (PPAT) OTXK12ZB PUR1_HUMAN Decreases Expression [132]
Lymphotoxin-beta (LTB) OTUFS8CF TNFC_HUMAN Decreases Expression [132]
Early activation antigen CD69 (CD69) OTGJHSVP CD69_HUMAN Increases Expression [132]
Src-like-adapter (SLA) OTV17DY2 SLAP1_HUMAN Increases Expression [132]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Increases Expression [132]
Four and a half LIM domains protein 1 (FHL1) OTN535SU FHL1_HUMAN Increases Expression [132]
Protein-tyrosine kinase 2-beta (PTK2B) OTGAS0I8 FAK2_HUMAN Increases Expression [132]
Transcription factor HES-1 (HES1) OT8P19W2 HES1_HUMAN Decreases Expression [132]
Nuclear factor interleukin-3-regulated protein (NFIL3) OTQH9HM3 NFIL3_HUMAN Increases Expression [132]
Pre-rRNA-processing protein TSR1 homolog (TSR1) OTCVZFL9 TSR1_HUMAN Decreases Expression [132]
Neurobeachin-like protein 2 (NBEAL2) OTMCAXWR NBEL2_HUMAN Increases Expression [132]
Protein FAM216A (FAM216A) OTL6I6AI F216A_HUMAN Decreases Expression [132]
Junctional adhesion molecule C (JAM3) OTX0F9QL JAM3_HUMAN Increases Expression [132]
Coiled-coil domain-containing protein 86 (CCDC86) OT5YQ0R0 CCD86_HUMAN Decreases Expression [132]
Thiol S-methyltransferase TMT1A (TMT1A) OT4IAAZP TMT1A_HUMAN Increases Expression [132]
Cadherin EGF LAG seven-pass G-type receptor 3 (CELSR3) OT8P6QNJ CELR3_HUMAN Decreases Expression [132]
PALM2-AKAP2 fusion protein (PALM2AKAP2) OTI618VF PLAK2_HUMAN Increases Expression [132]
Nucleolar protein 16 (NOP16) OT2829ZC NOP16_HUMAN Decreases Expression [132]
Nucleolar complex protein 2 homolog (NOC2L) OTNT7R33 NOC2L_HUMAN Decreases Expression [132]
Plexin-D1 (PLXND1) OTNK9ALK PLXD1_HUMAN Increases Expression [132]
Rho family-interacting cell polarization regulator 2 (RIPOR2) OTXB6LIR RIPR2_HUMAN Increases Expression [132]
Beta/gamma crystallin domain-containing protein 1 (CRYBG1) OTIPDI15 CRBG1_HUMAN Increases Expression [132]
Trefoil factor 1 (TFF1) OTCYQH4F TFF1_HUMAN Increases Expression [161]
Serine/threonine-protein kinase Sgk1 (SGK1) OT301T1U SGK1_HUMAN Increases Expression [150]
Period circadian protein homolog 1 (PER1) OTVQF3WX PER1_HUMAN Increases Expression [150]
Macrophage colony-stimulating factor 1 receptor (CSF1R) OTDYTB9C CSF1R_HUMAN Increases Expression [150]
Amine oxidase A (MAOA) OT8NIWMQ AOFA_HUMAN Increases Expression [150]
Olfactomedin-4 (OLFM4) OTELHN9L OLFM4_HUMAN Increases Expression [150]
Cytochrome P450 2C9 (CYP2C9) OTGLBN29 CP2C9_HUMAN Increases Expression [162]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Increases Expression [162]
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Increases Expression [163]
Nuclear receptor subfamily 1 group I member 3 (NR1I3) OTS3SGH7 NR1I3_HUMAN Increases Expression [164]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Decreases Expression [165]
Pulmonary surfactant-associated protein B (SFTPB) OTOHS07E PSPB_HUMAN Increases Expression [166]
Pulmonary surfactant-associated protein A1 (SFTPA1) OT87XL1U SFTA1_HUMAN Decreases Expression [166]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Decreases Expression [167]
Cytochrome P450 2A6 (CYP2A6) OT52TWG3 CP2A6_HUMAN Increases Expression [168]
Hepatocyte nuclear factor 4-alpha (HNF4A) OTY1TOAB HNF4A_HUMAN Increases Expression [168]
Sterol 26-hydroxylase, mitochondrial (CYP27A1) OT649C01 CP27A_HUMAN Increases Expression [169]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Expression [170]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Decreases Activity [170]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Decreases Activity [170]
Mineralocorticoid receptor (NR3C2) OT0F2V2Z MCR_HUMAN Increases Expression [170]
Retinoic acid receptor alpha (RARA) OT192V9V RARA_HUMAN Increases Expression [170]
COUP transcription factor 1 (NR2F1) OTGWZWYL COT1_HUMAN Increases Expression [170]
Tyrosine aminotransferase (TAT) OT2CJ91O ATTY_HUMAN Increases Expression [170]
Retinoic acid receptor RXR-alpha (RXRA) OTP1TBDM RXRA_HUMAN Increases Expression [170]
Nuclear receptor ROR-alpha (RORA) OTGQT12P RORA_HUMAN Increases Expression [170]
Nuclear receptor subfamily 2 group C member 2 (NR2C2) OTDZWVOJ NR2C2_HUMAN Increases Expression [170]
Histone deacetylase 4 (HDAC4) OTQNGD32 HDAC4_HUMAN Increases Expression [170]
Nuclear factor NF-kappa-B p100 subunit (NFKB2) OTS231V7 NFKB2_HUMAN Increases Expression [170]
Oxysterols receptor LXR-alpha (NR1H3) OT54YZ9I NR1H3_HUMAN Increases Expression [170]
Nuclear receptor subfamily 6 group A member 1 (NR6A1) OTFZOOQ9 NR6A1_HUMAN Increases Expression [170]
Nuclear receptor coactivator 2 (NCOA2) OTMQFPBB NCOA2_HUMAN Increases Expression [170]
Nuclear receptor coactivator 1 (NCOA1) OTLIUJQD NCOA1_HUMAN Increases Expression [170]
Histone acetyltransferase KAT2B (KAT2B) OTWQITWK KAT2B_HUMAN Increases Expression [170]
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) OTHCDQ22 PRGC1_HUMAN Increases Expression [170]
Organic solute transporter subunit alpha (SLC51A) OTDJRZ0P OSTA_HUMAN Affects Expression [171]
Organic solute transporter subunit beta (SLC51B) OT4WYPSR OSTB_HUMAN Increases Expression [171]
Toll-like receptor 4 (TLR4) OTP7ML3S TLR4_HUMAN Increases Expression [134]
Aquaporin-7 (AQP7) OTSOSZEE AQP7_HUMAN Increases Expression [134]
Lipid transferase CIDEA (CIDEA) OTDUTSOV CIDEA_HUMAN Increases Expression [134]
Renin receptor (ATP6AP2) OT0IABVV RENR_HUMAN Decreases Expression [134]
Complement factor D (CFD) OTLNRXB6 CFAD_HUMAN Increases Expression [134]
Angiotensinogen (AGT) OTBZLYR3 ANGT_HUMAN Increases Expression [134]
Beta-nerve growth factor (NGF) OTOLABJT NGF_HUMAN Decreases Expression [134]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Decreases Expression [134]
Retinol-binding protein 4 (RBP4) OTL9RBH5 RET4_HUMAN Increases Expression [134]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Increases Expression [134]
Thrombospondin-1 (THBS1) OT0ECWK3 TSP1_HUMAN Increases Expression [134]
Osteopontin (SPP1) OTJGC23Y OSTP_HUMAN Increases Expression [134]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Increases Expression [134]
Fatty acid-binding protein, adipocyte (FABP4) OT3DKFOU FABP4_HUMAN Increases Expression [134]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Increases Expression [134]
Vascular endothelial growth factor receptor 1 (FLT1) OTT0OGYS VGFR1_HUMAN Increases Expression [134]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Decreases Expression [134]
Glutathione peroxidase 3 (GPX3) OT6PK94R GPX3_HUMAN Increases Expression [134]
Zinc-alpha-2-glycoprotein (AZGP1) OTPD9TDR ZA2G_HUMAN Increases Expression [134]
11-beta-hydroxysteroid dehydrogenase 1 (HSD11B1) OTO7FJA9 DHI1_HUMAN Increases Expression [134]
Nitric oxide synthase 3 (NOS3) OTLDT7NR NOS3_HUMAN Increases Expression [134]
Pro-adrenomedullin (ADM) OT7T0TA4 ADML_HUMAN Increases Expression [134]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Decreases Expression [134]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Increases Expression [134]
Phosphatidate phosphatase LPIN1 (LPIN1) OTQ75KF2 LPIN1_HUMAN Increases Expression [134]
Adiponectin (ADIPOQ) OTNX23LE ADIPO_HUMAN Increases Expression [134]
Lipid transferase CIDEC (CIDEC) OTMDZ56K CIDEC_HUMAN Increases Expression [134]
NAD-dependent protein deacetylase sirtuin-1 (SIRT1) OTAYZMOY SIR1_HUMAN Increases Expression [134]
Histone-lysine N-methyltransferase PRDM16 (PRDM16) OT0BGA27 PRD16_HUMAN Decreases Expression [134]
Apelin (APLN) OTSWJD7B APEL_HUMAN Decreases Expression [134]
Hepatic sodium/bile acid cotransporter (SLC10A1) OTUJVMCL NTCP_HUMAN Increases Expression [172]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Increases Expression [173]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Increases Expression [173]
Cytochrome P450 2S1 (CYP2S1) OTKHX4RF CP2S1_HUMAN Decreases Expression [174]
S-adenosylmethionine synthase isoform type-2 (MAT2A) OTFJMIQR METK2_HUMAN Increases Expression [175]
Glutathione reductase, mitochondrial (GSR) OTM2TUYM GSHR_HUMAN Increases Expression [176]
Metallothionein-2 (MT2A) OTHOACHD MT2_HUMAN Increases Expression [177]
Glucoside xylosyltransferase 2 (GXYLT2) OTMLQQKP GXLT2_HUMAN Decreases Expression [135]
Tetraspanin-11 (TSPAN11) OT3GJF1N TSN11_HUMAN Decreases Expression [135]
Glutamate-rich protein 2 (ERICH2) OT0QA5Z1 ERIC2_HUMAN Decreases Expression [135]
Pleckstrin homology domain-containing family G member 3 (PLEKHG3) OTF6I8RV PKHG3_HUMAN Increases Expression [135]
Coiled-coil domain-containing protein 69 (CCDC69) OT43MI0R CCD69_HUMAN Increases Expression [135]
Very-long-chain (HACD1) OTEC7EP7 HACD1_HUMAN Increases Expression [135]
Isthmin-1 (ISM1) OTZTK2TV ISM1_HUMAN Increases Expression [135]
Transmembrane protein 233 (TMEM233) OT9J7BRF TM233_HUMAN Decreases Expression [135]
PDZ and LIM domain protein 1 (PDLIM1) OT4EGCPG PDLI1_HUMAN Increases Expression [135]
Agrin (AGRN) OTWJENAZ AGRIN_HUMAN Decreases Expression [135]
Procollagen-lysine,2-oxoglutarate 5-dioxygenase 2 (PLOD2) OTKOZRZP PLOD2_HUMAN Decreases Expression [135]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta (PIK3C2B) OTY2PROB P3C2B_HUMAN Increases Expression [135]
Acetyl-CoA carboxylase 2 (ACACB) OT96UIP1 ACACB_HUMAN Increases Expression [135]
Dihydropyrimidinase-related protein 4 (DPYSL4) OT3SBS2S DPYL4_HUMAN Decreases Expression [135]
Cdc42 effector protein 2 (CDC42EP2) OTX3YDPN BORG1_HUMAN Increases Expression [135]
Glutathione S-transferase 3, mitochondrial (MGST3) OTYK80JA MGST3_HUMAN Increases Expression [135]
Calmegin (CLGN) OTEWVFQV CLGN_HUMAN Decreases Expression [135]
Microtubule-associated serine/threonine-protein kinase 4 (MAST4) OT3LOE2J MAST4_HUMAN Increases Expression [135]
Synaptojanin-2 (SYNJ2) OTLRHXP1 SYNJ2_HUMAN Decreases Expression [135]
Serine/threonine-protein kinase DCLK1 (DCLK1) OTVSPS98 DCLK1_HUMAN Increases Expression [135]
Mothers against decapentaplegic homolog 7 (SMAD7) OTSLHWF4 SMAD7_HUMAN Decreases Expression [135]
1-acyl-sn-glycerol-3-phosphate acyltransferase beta (AGPAT2) OT5I4Y9K PLCB_HUMAN Increases Expression [135]
Low-density lipoprotein receptor class A domain-containing protein 4 (LDLRAD4) OTQUX50Z LRAD4_HUMAN Decreases Expression [135]
Membrane-associated progesterone receptor component 2 (PGRMC2) OTH6G1CV PGRC2_HUMAN Increases Expression [135]
Protein SLC31A2 (SLC31A2) OTQC136Q COPT2_HUMAN Decreases Expression [135]
Prolyl 4-hydroxylase subunit alpha-2 (P4HA2) OTP45YKX P4HA2_HUMAN Decreases Expression [135]
Glycogenin-2 (GYG2) OTAJ7YEW GLYG2_HUMAN Increases Expression [135]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Increases Expression [135]
D-3-phosphoglycerate dehydrogenase (PHGDH) OT1LMRTG SERA_HUMAN Decreases Expression [135]
Rho GTPase-activating protein 6 (ARHGAP6) OTNVXXFX RHG06_HUMAN Increases Expression [135]
Cytohesin-3 (CYTH3) OTBXAT3Z CYH3_HUMAN Increases Expression [135]
Perilipin-1 (PLIN1) OT3OAAZ4 PLIN1_HUMAN Increases Expression [135]
Acyl-CoA (FADS1) OTUYOYHX FADS1_HUMAN Increases Expression [135]
Protein-tyrosine sulfotransferase 1 (TPST1) OTDPQKEA TPST1_HUMAN Decreases Expression [135]
DNA polymerase zeta catalytic subunit (REV3L) OT0OP8EJ REV3L_HUMAN Increases Expression [135]
Sushi repeat-containing protein SRPX2 (SRPX2) OT6A63TX SRPX2_HUMAN Increases Expression [135]
Thiamine transporter 1 (SLC19A2) OTH5SB0M S19A2_HUMAN Increases Expression [135]
Receptor activity-modifying protein 1 (RAMP1) OT7UT2XB RAMP1_HUMAN Increases Expression [135]
Slit homolog 3 protein (SLIT3) OTU8MKEU SLIT3_HUMAN Decreases Expression [135]
Multiple epidermal growth factor-like domains protein 6 (MEGF6) OTEUYTP1 MEGF6_HUMAN Decreases Expression [135]
Rho-associated protein kinase 2 (ROCK2) OTVYN14T ROCK2_HUMAN Increases Expression [135]
Cartilage intermediate layer protein 1 (CILP) OTKEY2NJ CILP1_HUMAN Increases Expression [135]
Citrate synthase, mitochondrial (CS) OTYLYXMO CISY_HUMAN Increases Expression [135]
Sperm-associated antigen 7 (SPAG7) OTSDFA2D SPAG7_HUMAN Decreases Expression [135]
Claudin-11 (CLDN11) OTNN6UTL CLD11_HUMAN Increases Expression [135]
E3 ubiquitin-protein ligase MYCBP2 (MYCBP2) OTHODA1F MYCB2_HUMAN Increases Expression [135]
Protein phosphatase 1B (PPM1B) OTZMH6V3 PPM1B_HUMAN Increases Expression [135]
Cytosolic 10-formyltetrahydrofolate dehydrogenase (ALDH1L1) OT15HOJX AL1L1_HUMAN Increases Expression [135]
Diacylglycerol O-acyltransferase 1 (DGAT1) OTL104WL DGAT1_HUMAN Increases Expression [135]
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1 (DDAH1) OT1U2GWG DDAH1_HUMAN Increases Expression [135]
Serine/threonine-protein kinase 17B (STK17B) OT4NYNO8 ST17B_HUMAN Increases Expression [135]
Slit homolog 2 protein (SLIT2) OTLS2RJ4 SLIT2_HUMAN Decreases Expression [135]
Indolethylamine N-methyltransferase (INMT) OT5NWOZH INMT_HUMAN Increases Expression [135]
Neurexophilin-4 (NXPH4) OTV057AG NXPH4_HUMAN Decreases Expression [135]
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B (PDE8B) OT4217NK PDE8B_HUMAN Increases Expression [135]
CUGBP Elav-like family member 2 (CELF2) OTLJJ4VT CELF2_HUMAN Increases Expression [135]
Tumor necrosis factor alpha-induced protein 8 (TNFAIP8) OT1G9297 TFIP8_HUMAN Increases Expression [135]
Angiopoietin-related protein 1 (ANGPTL1) OTXIN6V5 ANGL1_HUMAN Increases Expression [135]
Zinc finger protein SNAI1 (SNAI1) OTDPYAMC SNAI1_HUMAN Decreases Expression [135]
Cholesterol 25-hydroxylase (CH25H) OT9S2BSW CH25H_HUMAN Decreases Expression [135]
Cytochrome b5 (CYB5A) OT6SN4RM CYB5_HUMAN Increases Expression [135]
All-trans-retinol dehydrogenase ADH1B (ADH1B) OTV3TB81 ADH1B_HUMAN Increases Expression [135]
Alcohol dehydrogenase 1C (ADH1C) OTO1DV7F ADH1G_HUMAN Increases Expression [135]
Haptoglobin-related protein (HPR) OTXSC9UB HPTR_HUMAN Increases Expression [135]
Urokinase-type plasminogen activator (PLAU) OTX0QGKK UROK_HUMAN Decreases Expression [135]
Tissue-type plasminogen activator (PLAT) OTQPDNAB TPA_HUMAN Decreases Expression [135]
Carbonic anhydrase 2 (CA2) OTJRMUAG CAH2_HUMAN Increases Expression [135]
Argininosuccinate synthase (ASS1) OT4ZMG0Q ASSY_HUMAN Increases Expression [135]
Alpha-2-macroglobulin (A2M) OTFTX90K A2MG_HUMAN Increases Expression [135]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Increases Expression [135]
Collagen alpha-1(III) chain (COL3A1) OTT1EMLM CO3A1_HUMAN Decreases Expression [135]
Collagen alpha-1(IV) chain (COL4A1) OTL6D1YE CO4A1_HUMAN Increases Expression [135]
Apolipoprotein E (APOE) OTFOWL2H APOE_HUMAN Increases Expression [135]
Myelin basic protein (MBP) OTFZCEDB MBP_HUMAN Increases Expression [135]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Decreases Expression [135]
Catalase (CAT) OTHEBX9R CATA_HUMAN Increases Expression [135]
HLA class I histocompatibility antigen, A alpha chain (HLA-A) OTAH14LU HLAA_HUMAN Decreases Expression [135]
Metallothionein-1A (MT1A) OTKBH52X MT1A_HUMAN Increases Expression [135]
Fatty acid-binding protein, heart (FABP3) OT562DA1 FABPH_HUMAN Increases Expression [135]
Tetranectin (CLEC3B) OTFD29NF TETN_HUMAN Increases Expression [135]
Collagen alpha-2(V) chain (COL5A2) OT5VOSQE CO5A2_HUMAN Decreases Expression [135]
Gelsolin (GSN) OT4KS2UU GELS_HUMAN Increases Expression [135]
Glycogen phosphorylase, liver form (PYGL) OTS1YFGR PYGL_HUMAN Increases Expression [135]
Lipoprotein lipase (LPL) OTTW0267 LIPL_HUMAN Increases Expression [135]
Glia-derived nexin (SERPINE2) OTYF5340 GDN_HUMAN Decreases Expression [135]
Acyl-CoA-binding protein (DBI) OT884QY9 ACBP_HUMAN Increases Expression [135]
L-lactate dehydrogenase B chain (LDHB) OT9B1CT3 LDHB_HUMAN Increases Expression [135]
Neurofilament light polypeptide (NEFL) OTQESJV4 NFL_HUMAN Increases Expression [135]
Alcohol dehydrogenase 1A (ADH1A) OTTS983E ADH1A_HUMAN Increases Expression [135]
Cathepsin D (CTSD) OTQZ36F3 CATD_HUMAN Decreases Expression [135]
Metallothionein-1B (MT1B) OTUA4FFH MT1B_HUMAN Increases Expression [135]
Decorin (DCN) OTWLJL7K PGS2_HUMAN Increases Expression [135]
Insulin-like growth factor 1 receptor (IGF1R) OTXJIF13 IGF1R_HUMAN Decreases Expression [135]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Decreases Expression [135]
Annexin A6 (ANXA6) OT9KIQ0Y ANXA6_HUMAN Increases Expression [135]
Amino acid transporter heavy chain SLC3A2 (SLC3A2) OTBR33M9 4F2_HUMAN Decreases Expression [135]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Decreases Expression [135]
Stromelysin-1 (MMP3) OTGBI74Z MMP3_HUMAN Decreases Expression [135]
Inhibin beta A chain (INHBA) OTSP64PQ INHBA_HUMAN Decreases Expression [135]
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial (PDHA1) OTGEU8IK ODPA_HUMAN Increases Expression [135]
Matrilysin (MMP7) OTVT3SEJ MMP7_HUMAN Increases Expression [135]
Tropomyosin alpha-1 chain (TPM1) OTD73X6R TPM1_HUMAN Decreases Expression [135]
Annexin A4 (ANXA4) OTUCRYXL ANXA4_HUMAN Increases Expression [135]
Inhibin beta B chain (INHBB) OT2QLD11 INHBB_HUMAN Increases Expression [135]
Interferon alpha-inducible protein 6 (IFI6) OTWOOAM4 IFI6_HUMAN Increases Expression [135]
Protein ELFN1 (ELFN1) OTM7M52U ELFN1_HUMAN Decreases Expression [135]
Serum amyloid A-1 protein (SAA1) OTO2D8S0 SAA1_HUMAN Increases Expression [135]
Zinc finger protein GLI2 (GLI2) OTIRV97L GLI2_HUMAN Decreases Expression [135]
HLA class I histocompatibility antigen, C alpha chain (HLA-C) OTV38BUJ HLAC_HUMAN Decreases Expression [135]
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial (DLAT) OT9LBJVN ODP2_HUMAN Increases Expression [135]
Microsomal glutathione S-transferase 1 (MGST1) OTGN1KVZ MGST1_HUMAN Increases Expression [135]
Tissue factor pathway inhibitor (TFPI) OTA0FX16 TFPI1_HUMAN Increases Expression [135]
Clusterin (CLU) OTQGG0JM CLUS_HUMAN Decreases Expression [135]
E3 SUMO-protein ligase EGR2 (EGR2) OTAVQ78J EGR2_HUMAN Decreases Expression [135]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Decreases Expression [135]
Collagen alpha-2(VI) chain (COL6A2) OTQC6PPO CO6A2_HUMAN Decreases Expression [135]
Collagen alpha-3(VI) chain (COL6A3) OTAS6R6I CO6A3_HUMAN Decreases Expression [135]
Nidogen-1 (NID1) OTKLBLS6 NID1_HUMAN Increases Expression [135]
Phospholipase A2, membrane associated (PLA2G2A) OT1NY7BF PA2GA_HUMAN Increases Expression [135]
Myosin light chain 6B (MYL6B) OTWTRGT7 MYL6B_HUMAN Decreases Expression [135]
Matrix metalloproteinase-9 (MMP9) OTB2QDAV MMP9_HUMAN Decreases Expression [135]
Leukemia inhibitory factor (LIF) OTO46S5S LIF_HUMAN Decreases Expression [135]
Glutamine synthetase (GLUL) OTYGTCGF GLNA_HUMAN Increases Expression [135]
Beta-1,4-galactosyltransferase 1 (B4GALT1) OTBCXEK7 B4GT1_HUMAN Decreases Expression [135]
Atrial natriuretic peptide receptor 1 (NPR1) OTRWART5 ANPRA_HUMAN Increases Expression [135]
Platelet glycoprotein 4 (CD36) OT5CZWKY CD36_HUMAN Increases Expression [135]
Rho-related GTP-binding protein RhoQ (RHOQ) OTUBTU57 RHOQ_HUMAN Increases Expression [135]
Endoglin (ENG) OTL2LSMI EGLN_HUMAN Decreases Expression [135]
Insulin-like growth factor-binding protein 3 (IGFBP3) OTIX63TX IBP3_HUMAN Decreases Expression [135]
Insulin-like growth factor-binding protein 2 (IGFBP2) OTG1P60E IBP2_HUMAN Increases Expression [135]
Alpha-2C adrenergic receptor (ADRA2C) OT5B9RKP ADA2C_HUMAN Increases Expression [135]
Cadherin-2 (CDH2) OTH0Y56P CADH2_HUMAN Decreases Expression [135]
C-X-C motif chemokine 2 (CXCL2) OTEJCYMY CXCL2_HUMAN Decreases Expression [135]
C-X-C motif chemokine 3 (CXCL3) OTSL94KH CXCL3_HUMAN Decreases Expression [135]
Interferon-induced GTP-binding protein Mx2 (MX2) OT05NF37 MX2_HUMAN Increases Expression [135]
B-cell lymphoma 3 protein (BCL3) OT1M5B95 BCL3_HUMAN Decreases Expression [135]
Interleukin-11 (IL11) OTXHN86R IL11_HUMAN Decreases Expression [135]
Collagen alpha-1(V) chain (COL5A1) OT24078H CO5A1_HUMAN Decreases Expression [135]
Cytoplasmic aconitate hydratase (ACO1) OT2VUR7L ACOHC_HUMAN Increases Expression [135]
Cannabinoid receptor 1 (CNR1) OTEALO6G CNR1_HUMAN Increases Expression [135]
Glycerol-3-phosphate dehydrogenase , cytoplasmic (GPD1) OTQW7TMB GPDA_HUMAN Increases Expression [135]
Midkine (MDK) OTF24HKC MK_HUMAN Decreases Expression [135]
Biglycan (BGN) OT3AV6IF PGS1_HUMAN Decreases Expression [135]
Liver carboxylesterase 1 (CES1) OT9L0LR8 EST1_HUMAN Increases Expression [135]
Prostaglandin G/H synthase 1 (PTGS1) OTHCRLEC PGH1_HUMAN Increases Expression [135]
Receptor-type tyrosine-protein phosphatase gamma (PTPRG) OT9N2WOF PTPRG_HUMAN Increases Expression [135]
Brain-derived neurotrophic factor (BDNF) OTLGH7EW BDNF_HUMAN Decreases Expression [135]
Plasma membrane calcium-transporting ATPase 4 (ATP2B4) OTMWFDAC AT2B4_HUMAN Increases Expression [135]
Cytochrome c oxidase subunit 7A1, mitochondrial (COX7A1) OTHV25GG CX7A1_HUMAN Increases Expression [135]
Interleukin-4 receptor subunit alpha (IL4R) OTTXOTCW IL4RA_HUMAN Decreases Expression [135]
Insulin-like growth factor-binding protein 5 (IGFBP5) OTRE5V0C IBP5_HUMAN Increases Expression [135]
ATP synthase subunit alpha, mitochondrial (ATP5F1A) OT3FZDLX ATPA_HUMAN Increases Expression [135]
Metallothionein-3 (MT3) OTVCZ7HI MT3_HUMAN Increases Expression [135]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Increases Expression [135]
Stomatin (STOM) OTC8R6EH STOM_HUMAN Increases Expression [135]
G0/G1 switch protein 2 (G0S2) OT8FL49L G0S2_HUMAN Increases Expression [135]
Phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1) OT5BZ1J9 P85A_HUMAN Increases Expression [135]
Leiomodin-1 (LMOD1) OTZ2MEMG LMOD1_HUMAN Increases Expression [135]
Myristoylated alanine-rich C-kinase substrate (MARCKS) OT7N056G MARCS_HUMAN Decreases Expression [135]
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial (ALDH4A1) OT25Z6XH AL4A1_HUMAN Increases Expression [135]
Peroxiredoxin-6 (PRDX6) OTS8KC8A PRDX6_HUMAN Increases Expression [135]
cAMP-dependent protein kinase type II-beta regulatory subunit (PRKAR2B) OTZEXEFH KAP3_HUMAN Increases Expression [135]
Transcription factor HIVEP2 (HIVEP2) OTVOMCW4 ZEP2_HUMAN Decreases Expression [135]
Pyrroline-5-carboxylate reductase 1, mitochondrial (PYCR1) OTQHB52T P5CR1_HUMAN Decreases Expression [135]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) OTB06ESI ACSL1_HUMAN Increases Expression [135]
Lymphocyte-specific protein 1 (LSP1) OTSPSIFO LSP1_HUMAN Decreases Expression [135]
Serine hydroxymethyltransferase, mitochondrial (SHMT2) OT5NCAZN GLYM_HUMAN Decreases Expression [135]
G protein-coupled receptor kinase 5 (GRK5) OTJK79EK GRK5_HUMAN Increases Expression [135]
Thrombospondin-2 (THBS2) OTXET551 TSP2_HUMAN Decreases Expression [135]
Fibrillin-2 (FBN2) OT3KYJQL FBN2_HUMAN Increases Expression [135]
Phosphoenolpyruvate carboxykinase, cytosolic (PCK1) OTNWEJ5Y PCKGC_HUMAN Increases Expression [135]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Decreases Expression [135]
Sterol regulatory element-binding protein 1 (SREBF1) OTWBRPAI SRBP1_HUMAN Increases Expression [135]
Serine/threonine-protein kinase receptor R3 (ACVRL1) OT1HQR88 ACVL1_HUMAN Increases Expression [135]
Lysosomal acid lipase/cholesteryl ester hydrolase (LIPA) OTIOLNHE LICH_HUMAN Increases Expression [135]
Collagen alpha-1(XV) chain (COL15A1) OTTFKK18 COFA1_HUMAN Decreases Expression [135]
Malate dehydrogenase, cytoplasmic (MDH1) OTJEO4E8 MDHC_HUMAN Increases Expression [135]
DNA-binding protein inhibitor ID-1 (ID1) OTKGNZN5 ID1_HUMAN Decreases Expression [135]
Mitogen-activated protein kinase kinase kinase 8 (MAP3K8) OTOZTA1F M3K8_HUMAN Increases Expression [135]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Increases Expression [135]
Cyclin-dependent kinase 4 inhibitor C (CDKN2C) OTCLOV90 CDN2C_HUMAN Increases Expression [135]
Excitatory amino acid transporter 1 (SLC1A3) OTILR60R EAA1_HUMAN Decreases Expression [135]
Prostaglandin F2-alpha receptor (PTGFR) OTUI456H PF2R_HUMAN Decreases Expression [135]
Prostaglandin E2 receptor EP3 subtype (PTGER3) OTQODQUN PE2R3_HUMAN Increases Expression [135]
Cathepsin K (CTSK) OTT3YX5O CATK_HUMAN Increases Expression [135]
Nicotinamide phosphoribosyltransferase (NAMPT) OTVJR3GL NAMPT_HUMAN Decreases Expression [135]
Aspartoacylase (ASPA) OTR2MWS4 ACY2_HUMAN Increases Expression [135]
Large proline-rich protein BAG6 (BAG6) OT4Z0S2U BAG6_HUMAN Decreases Expression [135]
B1 bradykinin receptor (BDKRB1) OT1DHSVQ BKRB1_HUMAN Decreases Expression [135]
Radiation-inducible immediate-early gene IEX-1 (IER3) OTZJI5FZ IEX1_HUMAN Decreases Expression [135]
Retinaldehyde dehydrogenase 3 (ALDH1A3) OT1C9NKQ AL1A3_HUMAN Increases Expression [135]
Sodium- and chloride-dependent glycine transporter 1 (SLC6A9) OTHRUON2 SC6A9_HUMAN Decreases Expression [135]
Tissue factor pathway inhibitor 2 (TFPI2) OTZCRWOR TFPI2_HUMAN Decreases Expression [135]
Fatty acid synthase (FASN) OTFII9KG FAS_HUMAN Increases Expression [135]
Amphiphysin (AMPH) OTWPGWZX AMPH_HUMAN Increases Expression [135]
Thrombospondin-3 (THBS3) OTDKMUBD TSP3_HUMAN Decreases Expression [135]
Placenta growth factor (PGF) OT5MF5DJ PLGF_HUMAN Decreases Expression [135]
Retinoic acid receptor responder protein 1 (RARRES1) OTETUPP5 TIG1_HUMAN Decreases Expression [135]
Selenoprotein P (SELENOP) OT02B8IR SEPP1_HUMAN Increases Expression [135]
Max-interacting protein 1 (MXI1) OTUQ9E0D MXI1_HUMAN Decreases Expression [135]
RNA-binding protein Nova-1 (NOVA1) OT6A9KHY NOVA1_HUMAN Increases Expression [135]
Caveolin-2 (CAV2) OT1FGRQX CAV2_HUMAN Increases Expression [135]
Glypican-3 (GPC3) OTWS8WSW GPC3_HUMAN Increases Expression [135]
Lumican (LUM) OTSRC874 LUM_HUMAN Decreases Expression [135]
Tricarboxylate transport protein, mitochondrial (SLC25A1) OTIDXQ9F TXTP_HUMAN Increases Expression [135]
Protein FosB (FOSB) OTW6C05J FOSB_HUMAN Increases Expression [135]
Sodium/myo-inositol cotransporter (SLC5A3) OT6FY2KA SC5A3_HUMAN Decreases Expression [135]
Phospholipase A and acyltransferase 3 (PLAAT3) OTVXXJ5K PLAT3_HUMAN Increases Expression [135]
Heat shock-related 70 kDa protein 2 (HSPA2) OTSDET7B HSP72_HUMAN Increases Expression [135]
Sodium/potassium-transporting ATPase subunit beta-3 (ATP1B3) OTOFL24U AT1B3_HUMAN Increases Expression [135]
Epithelial membrane protein 1 (EMP1) OTSZHUHQ EMP1_HUMAN Increases Expression [135]
Microfibrillar-associated protein 2 (MFAP2) OTMHVBTV MFAP2_HUMAN Decreases Expression [135]
GTP-binding protein GEM (GEM) OT6SK8ZV GEM_HUMAN Decreases Expression [135]
Growth/differentiation factor 10 (GDF10) OTEVXGJ7 GDF10_HUMAN Decreases Expression [135]
Laminin subunit beta-2 (LAMB2) OT71OI2Y LAMB2_HUMAN Decreases Expression [135]
GDNF family receptor alpha-1 (GFRA1) OT3WBVYB GFRA1_HUMAN Increases Expression [135]
Homeobox protein DLX-5 (DLX5) OTEEFBEU DLX5_HUMAN Decreases Expression [135]
Junctional adhesion molecule B (JAM2) OTHVJJRJ JAM2_HUMAN Decreases Expression [135]
Lysyl oxidase homolog 3 (LOXL3) OTLLY1QI LOXL3_HUMAN Decreases Expression [135]
Protein eva-1 homolog C (EVA1C) OT18YR25 EVA1C_HUMAN Increases Expression [135]
Reactive oxygen species modulator 1 (ROMO1) OTIEYVBW ROMO1_HUMAN Increases Expression [135]
Ras-related protein Rab-2A (RAB2A) OT6SK83U RAB2A_HUMAN Increases Expression [135]
Somatostatin (SST) OTY75GQH SMS_HUMAN Decreases Expression [135]
Ras-related protein R-Ras2 (RRAS2) OT83NCEB RRAS2_HUMAN Increases Expression [135]
Thymosin beta-4 (TMSB4X) OT9HPLP3 TYB4_HUMAN Increases Expression [135]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Decreases Expression [135]
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L) OTSSOMUP RPAB5_HUMAN Increases Expression [135]
Gamma-aminobutyric acid receptor subunit epsilon (GABRE) OTXF5ICU GBRE_HUMAN Decreases Expression [135]
Sushi repeat-containing protein SRPX (SRPX) OT5B9LXS SRPX_HUMAN Increases Expression [135]
C-X-C motif chemokine 6 (CXCL6) OTFTCQ4O CXCL6_HUMAN Decreases Expression [135]
Metallothionein-1H (MT1H) OT0MVBM6 MT1H_HUMAN Increases Expression [135]
Metallothionein-1X (MT1X) OT9AKFVS MT1X_HUMAN Increases Expression [135]
Nucleobindin-2 (NUCB2) OTHO6JWN NUCB2_HUMAN Decreases Expression [135]
4-aminobutyrate aminotransferase, mitochondrial (ABAT) OTXAGR7J GABT_HUMAN Increases Expression [135]
Tumor necrosis factor-inducible gene 6 protein (TNFAIP6) OT1SLUZH TSG6_HUMAN Decreases Expression [135]
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) OTOVM4D4 SPTB2_HUMAN Increases Expression [135]
Peripheral myelin protein 22 (PMP22) OTXWYWCZ PMP22_HUMAN Increases Expression [135]
Fatty acid-binding protein 5 (FABP5) OTNM186C FABP5_HUMAN Increases Expression [135]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Decreases Expression [135]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1) OTEUYEW6 ROR1_HUMAN Increases Expression [135]
D-beta-hydroxybutyrate dehydrogenase, mitochondrial (BDH1) OT62RL5P BDH_HUMAN Increases Expression [135]
Collagen alpha-1(VII) chain (COL7A1) OT3MIRZJ CO7A1_HUMAN Decreases Expression [135]
DNA-binding protein inhibitor ID-3 (ID3) OTUULW5Z ID3_HUMAN Decreases Expression [135]
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (GCNT1) OTF6OC66 GCNT1_HUMAN Increases Expression [135]
Caveolin-1 (CAV1) OTEZUR1L CAV1_HUMAN Increases Expression [135]
Transforming growth factor beta receptor type 3 (TGFBR3) OTQOOUC4 TGBR3_HUMAN Increases Expression [135]
Peroxisome proliferator-activated receptor delta (PPARD) OTI4WTOP PPARD_HUMAN Decreases Expression [135]
Mevalonate kinase (MVK) OTHJCUKT KIME_HUMAN Increases Expression [135]
1,4-alpha-glucan-branching enzyme (GBE1) OTK2N05B GLGB_HUMAN Increases Expression [135]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Increases Expression [135]
Hormone-sensitive lipase (LIPE) OTMMVJ8A LIPS_HUMAN Increases Expression [135]
Collagen alpha-1(XIV) chain (COL14A1) OTLNJ13O COEA1_HUMAN Decreases Expression [135]
Aldehyde oxidase (AOX1) OT2FZP6H AOXA_HUMAN Increases Expression [135]
Prolow-density lipoprotein receptor-related protein 1 (LRP1) OTHTEH4G LRP1_HUMAN Decreases Expression [135]
Nexilin (NEXN) OTKB0B0H NEXN_HUMAN Increases Expression [135]
Forkhead box protein O1 (FOXO1) OTPJRB6D FOXO1_HUMAN Increases Expression [135]
EGF-containing fibulin-like extracellular matrix protein 1 (EFEMP1) OTZVUOOB FBLN3_HUMAN Decreases Expression [135]
Trophinin (TRO) OTRZQMU8 TROP_HUMAN Decreases Expression [135]
Epidermal growth factor receptor kinase substrate 8 (EPS8) OTZ6ES6V EPS8_HUMAN Increases Expression [135]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Decreases Expression [135]
Pappalysin-1 (PAPPA) OTTTG9PG PAPP1_HUMAN Decreases Expression [135]
Methanethiol oxidase (SELENBP1) OT3NZNTR SBP1_HUMAN Increases Expression [135]
Beta-2-syntrophin (SNTB2) OTIVMQ2S SNTB2_HUMAN Increases Expression [135]
Protein phosphatase 1 regulatory subunit 1A (PPP1R1A) OTGTAGCV PPR1A_HUMAN Increases Expression [135]
Cullin-4B (CUL4B) OT2QX4DO CUL4B_HUMAN Increases Expression [135]
Integrin alpha-7 (ITGA7) OTTBTAYW ITA7_HUMAN Increases Expression [135]
Isopentenyl-diphosphate Delta-isomerase 1 (IDI1) OTGM06VJ IDI1_HUMAN Increases Expression [135]
Runt-related transcription factor 2 (RUNX2) OT97RQQM RUNX2_HUMAN Decreases Expression [135]
Protein Tob2 (TOB2) OTEEHL60 TOB2_HUMAN Increases Expression [135]
Four and a half LIM domains protein 2 (FHL2) OT0OAYWT FHL2_HUMAN Decreases Expression [135]
Dihydropyrimidinase-related protein 3 (DPYSL3) OTINJV20 DPYL3_HUMAN Decreases Expression [135]
Frizzled-2 (FZD2) OT952ML1 FZD2_HUMAN Decreases Expression [135]
Transforming growth factor beta activator LRRC32 (LRRC32) OTG7EDZL LRC32_HUMAN Decreases Expression [135]
Squalene monooxygenase (SQLE) OT0GGRDO ERG1_HUMAN Increases Expression [135]
KN motif and ankyrin repeat domain-containing protein 1 (KANK1) OT2E7A6W KANK1_HUMAN Increases Expression [135]
Neutral alpha-glucosidase AB (GANAB) OTYLXY4M GANAB_HUMAN Decreases Expression [135]
Potassium voltage-gated channel subfamily B member 1 (KCNB1) OTLCU4FR KCNB1_HUMAN Increases Expression [135]
Delta(14)-sterol reductase LBR (LBR) OT1HG3HG LBR_HUMAN Increases Expression [135]
Latent-transforming growth factor beta-binding protein 2 (LTBP2) OTS88GSD LTBP2_HUMAN Decreases Expression [135]
Periostin (POSTN) OTWP62UA POSTN_HUMAN Decreases Expression [135]
Platelet-activating factor acetylhydrolase IB subunit alpha1 (PAFAH1B3) OT6A9JT8 PA1B3_HUMAN Decreases Expression [135]
Inorganic pyrophosphatase (PPA1) OTHZK1QB IPYR_HUMAN Increases Expression [135]
Platelet-derived growth factor receptor-like protein (PDGFRL) OTJPRECT PGFRL_HUMAN Decreases Expression [135]
Delta(24)-sterol reductase (DHCR24) OTP301JW DHC24_HUMAN Increases Expression [135]
Transforming growth factor-beta-induced protein ig-h3 (TGFBI) OTR443C5 BGH3_HUMAN Decreases Expression [135]
2'-5'-oligoadenylate synthase-like protein (OASL) OTZ05YRP OASL_HUMAN Increases Expression [135]
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating (NSDHL) OTK3EJFD NSDHL_HUMAN Increases Expression [135]
NGFI-A-binding protein 2 (NAB2) OTG4BDF3 NAB2_HUMAN Decreases Expression [135]
Ovarian cancer G-protein coupled receptor 1 (GPR68) OT1NXSMN OGR1_HUMAN Decreases Expression [135]
Myosin light chain kinase, smooth muscle (MYLK) OT78QB4A MYLK_HUMAN Increases Expression [135]
Adipogenesis regulatory factor (ADIRF) OTTJP8D4 ADIRF_HUMAN Increases Expression [135]
Neuronatin (NNAT) OTNRLO7G NNAT_HUMAN Increases Expression [135]
Neuronal regeneration-related protein (NREP) OT2AZPKK NREP_HUMAN Decreases Expression [135]
kinase isozyme 4, mitochondrial (PDK4) OTCMHMBZ PDK4_HUMAN Increases Expression [135]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Decreases Expression [135]
Thiosulfate sulfurtransferase (TST) OTZ4F5LK THTR_HUMAN Increases Expression [135]
NADP-dependent malic enzyme, mitochondrial (ME3) OT3XMLYG MAON_HUMAN Increases Expression [135]
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH) OTJDOL20 HCDH_HUMAN Increases Expression [135]
Amine oxidase 3 (AOC3) OT30YKV0 AOC3_HUMAN Increases Expression [135]
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 (PFKFB4) OTQYEXL2 F264_HUMAN Decreases Expression [135]
Cysteine dioxygenase type 1 (CDO1) OTLG1P77 CDO1_HUMAN Increases Expression [135]
Transmembrane protein 132A (TMEM132A) OTNUI7O1 T132A_HUMAN Decreases Expression [135]
Kinesin-like protein KIF26B (KIF26B) OTVHWIKR KI26B_HUMAN Decreases Expression [135]
Transmembrane protein 44 (TMEM44) OTRUF467 TMM44_HUMAN Decreases Expression [135]
PWWP domain-containing DNA repair factor 3A (PWWP3A) OTXQVL4U PWP3A_HUMAN Decreases Expression [135]
Sushi, von Willebrand factor type A, EGF and pentraxin domain-containing protein 1 (SVEP1) OTOBICRD SVEP1_HUMAN Increases Expression [135]
Fibronectin type III domain-containing protein 1 (FNDC1) OTU2BA12 FNDC1_HUMAN Decreases Expression [135]
BolA-like protein 3 (BOLA3) OTDEDY0S BOLA3_HUMAN Increases Expression [135]
Cordon-bleu protein-like 1 (COBLL1) OTQFN1TC COBL1_HUMAN Increases Expression [135]
Mesoderm-specific transcript homolog protein (MEST) OT8Q4U8Y MEST_HUMAN Increases Expression [135]
Proline-rich transmembrane protein 3 (PRRT3) OT231D18 PRRT3_HUMAN Increases Expression [135]
SH3 domain-containing protein 19 (SH3D19) OTVU3VS2 SH319_HUMAN Increases Expression [135]
Dedicator of cytokinesis protein 11 (DOCK11) OTFSTN6A DOC11_HUMAN Increases Expression [135]
Long-chain fatty acid transport protein 3 (SLC27A3) OTXB60L7 S27A3_HUMAN Increases Expression [135]
Transcription factor HIVEP3 (HIVEP3) OTM3QT3L ZEP3_HUMAN Increases Expression [135]
Transmembrane protein 170B (TMEM170B) OT4AS8RJ T170B_HUMAN Increases Expression [135]
Immediate early response gene 5-like protein (IER5L) OT6IG629 IER5L_HUMAN Decreases Expression [135]
E3 ubiquitin-protein ligase RNF187 (RNF187) OTXTN1HP RN187_HUMAN Decreases Expression [135]
Collagen alpha-1(XIII) chain (COL13A1) OTM9IM6J CODA1_HUMAN Decreases Expression [135]
Opioid growth factor receptor-like protein 1 (OGFRL1) OT6QGBYE OGRL1_HUMAN Increases Expression [135]
Synaptophysin-like protein 2 (SYPL2) OT6CV0CA SYPL2_HUMAN Increases Expression [135]
Phospholipid phosphatase 4 (PLPP4) OTH5EXZC PLPP4_HUMAN Decreases Expression [135]
Pikachurin (EGFLAM) OTACZZJ0 EGFLA_HUMAN Increases Expression [135]
Tensin-2 (TNS2) OTP72P0F TENS2_HUMAN Increases Expression [135]
Meteorin-like protein (METRNL) OTB0DDL0 METRL_HUMAN Decreases Expression [135]
La-related protein 1B (LARP1B) OT9JZ7K5 LAR1B_HUMAN Increases Expression [135]
Protein sel-1 homolog 3 (SEL1L3) OT10N6Z2 SE1L3_HUMAN Decreases Expression [135]
Scavenger receptor class A member 3 (SCARA3) OT46I38Y SCAR3_HUMAN Decreases Expression [135]
Dermokine (DMKN) OTRIGZMK DMKN_HUMAN Increases Expression [135]
Protein Jade-1 (JADE1) OTBPJIRI JADE1_HUMAN Increases Expression [135]
All-trans-retinol 13,14-reductase (RETSAT) OTC3AOPX RETST_HUMAN Increases Expression [135]
Caveolae-associated protein 1 (CAVIN1) OTFO915U CAVN1_HUMAN Increases Expression [135]
Lysophospholipid acyltransferase 5 (LPCAT3) OTWI96P4 MBOA5_HUMAN Increases Expression [135]
F-box only protein 42 (FBXO42) OTHPN53C FBX42_HUMAN Decreases Expression [135]
Connector enhancer of kinase suppressor of ras 3 (CNKSR3) OTXP4QH8 CNKR3_HUMAN Increases Expression [135]
Dehydrogenase/reductase SDR family member 4-like 2 (DHRS4L2) OTKH0NVX DR4L2_HUMAN Increases Expression [135]
Ras-like protein family member 11A (RASL11A) OTDO6CMY RSLBA_HUMAN Increases Expression [135]
Kelch-like protein 17 (KLHL17) OTUWIJIQ KLH17_HUMAN Decreases Expression [135]
Golgi-associated kinase 1B (GASK1B) OT2HPHEI GAK1B_HUMAN Increases Expression [135]
Sushi domain-containing protein 1 (SUSD1) OTR3UGLY SUSD1_HUMAN Increases Expression [135]
Suprabasin (SBSN) OT89RKJH SBSN_HUMAN Increases Expression [135]
Plexin domain-containing protein 2 (PLXDC2) OTS1FUV6 PXDC2_HUMAN Decreases Expression [135]
Inactive serine protease PAMR1 (PAMR1) OT83ZH5U PAMR1_HUMAN Decreases Expression [135]
Interleukin-20 receptor subunit beta (IL20RB) OTHFXK95 I20RB_HUMAN Decreases Expression [135]
Very-long-chain (HACD2) OTAZO9F6 HACD2_HUMAN Increases Expression [135]
Transmembrane protein 64 (TMEM64) OTO9IDFD TMM64_HUMAN Increases Expression [135]
Scavenger receptor class A member 5 (SCARA5) OTOVA96E SCAR5_HUMAN Increases Expression [135]
SPOC domain-containing protein 1 (SPOCD1) OTF4K46N SPOC1_HUMAN Increases Expression [135]
Nesprin-3 (SYNE3) OTEOJBYB SYNE3_HUMAN Increases Expression [135]
Zinc finger protein basonuclin-2 (BNC2) OTU22H9Z BNC2_HUMAN Decreases Expression [135]
DNA-binding protein RFX8 (RFX8) OT27SFGQ RFX8_HUMAN Decreases Expression [135]
TOM1-like protein 2 (TOM1L2) OTUXXUH8 TM1L2_HUMAN Increases Expression [135]
Protein phosphatase Slingshot homolog 2 (SSH2) OT8NCK82 SSH2_HUMAN Increases Expression [135]
Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (EEPD1) OTTOGO05 EEPD1_HUMAN Increases Expression [135]
Peroxiredoxin-like 2C (PRXL2C) OTI8ZAK8 PXL2C_HUMAN Increases Expression [135]
Protein mono-ADP-ribosyltransferase TIPARP (TIPARP) OTZ4BG4B PARPT_HUMAN Increases Expression [135]
LIM and senescent cell antigen-like-containing domain protein 2 (LIMS2) OTZ7IIPM LIMS2_HUMAN Increases Expression [135]
L-xylulose reductase (DCXR) OTYVXRXB DCXR_HUMAN Increases Expression [135]
Rho GTPase-activating protein 22 (ARHGAP22) OTXUQEFL RHG22_HUMAN Decreases Expression [135]
PX domain-containing protein kinase-like protein (PXK) OTSP1WLK PXK_HUMAN Decreases Expression [135]
Disheveled-associated activator of morphogenesis 2 (DAAM2) OTC1WVZT DAAM2_HUMAN Increases Expression [135]
Acyl-coenzyme A thioesterase 1 (ACOT1) OTXFL7WM ACOT1_HUMAN Increases Expression [135]
Regulating synaptic membrane exocytosis protein 1 (RIMS1) OT10T7CK RIMS1_HUMAN Increases Expression [135]
Metalloprotease TIKI1 (TRABD2A) OTVMA26J TIKI1_HUMAN Increases Expression [135]
Liprin-beta-1 (PPFIBP1) OTRA2S7B LIPB1_HUMAN Decreases Expression [135]
Chondroitin sulfate synthase 1 (CHSY1) OTB1XSSF CHSS1_HUMAN Decreases Expression [135]
Extracellular matrix organizing protein FRAS1 (FRAS1) OTLPESF3 FRAS1_HUMAN Increases Expression [135]
Beta-klotho (KLB) OTTKKFS8 KLOTB_HUMAN Increases Expression [135]
Protein O-mannosyl-transferase TMTC1 (TMTC1) OTZ7NW96 TMTC1_HUMAN Increases Expression [135]
5'-3' exonuclease PLD3 (PLD3) OTL07SP2 PLD3_HUMAN Decreases Expression [135]
Sodium/hydrogen exchanger 9 (SLC9A9) OT00PCW3 SL9A9_HUMAN Increases Expression [135]
Neuron navigator 3 (NAV3) OT97M1TR NAV3_HUMAN Increases Expression [135]
Prolyl 3-hydroxylase 2 (P3H2) OTY84H6U P3H2_HUMAN Decreases Expression [135]
DCN1-like protein 3 (DCUN1D3) OTG20VWE DCNL3_HUMAN Increases Expression [135]
Cullin-9 (CUL9) OTPUCLZT CUL9_HUMAN Decreases Expression [135]
Extracellular sulfatase Sulf-1 (SULF1) OTJCNCO0 SULF1_HUMAN Decreases Expression [135]
CD302 antigen (CD302) OTX580VU CD302_HUMAN Increases Expression [135]
Trafficking regulator of GLUT4 1 (TRARG1) OTQ1R3JD TARG1_HUMAN Increases Expression [135]
Polypeptide N-acetylgalactosaminyltransferase 12 (GALNT12) OTVIBUST GLT12_HUMAN Decreases Expression [135]
Solute carrier family 22 member 15 (SLC22A15) OT60WAAI S22AF_HUMAN Decreases Expression [135]
Protein APCDD1 (APCDD1) OTV9AD0L APCD1_HUMAN Increases Expression [135]
Cell cycle exit and neuronal differentiation protein 1 (CEND1) OTPHOC22 CEND_HUMAN Increases Expression [135]
ATP-binding cassette sub-family A member 6 (ABCA6) OTJJELUF ABCA6_HUMAN Increases Expression [135]
Glypican-2 (GPC2) OT3WSQE1 GPC2_HUMAN Decreases Expression [135]
Protein odd-skipped-related 2 (OSR2) OTYG371T OSR2_HUMAN Increases Expression [135]
Protein FAM43A (FAM43A) OT5RPQRE FA43A_HUMAN Increases Expression [135]
Glycerol-3-phosphate dehydrogenase 1-like protein (GPD1L) OTVLWW9T GPD1L_HUMAN Increases Expression [135]
Metallothionein-1M (MT1M) OTVT8PLU MT1M_HUMAN Increases Expression [135]
Maturin (MTURN) OTEBJNVG MTURN_HUMAN Increases Expression [135]
GTP-binding protein 8 (GTPBP8) OTI8X03A GTPB8_HUMAN Increases Expression [135]
Tetratricopeptide repeat protein 39C (TTC39C) OTKKI81C TT39C_HUMAN Increases Expression [135]
Refilin-B (RFLNB) OTI7ZM75 RFLB_HUMAN Decreases Expression [135]
Chondroitin sulfate N-acetylgalactosaminyltransferase 2 (CSGALNACT2) OT2SH7HJ CGAT2_HUMAN Decreases Expression [135]
Uncharacterized protein FAM241A (FAM241A) OTC12ETA F241A_HUMAN Increases Expression [135]
Interleukin-17 receptor C (IL17RC) OTEFOBSS I17RC_HUMAN Increases Expression [135]
Protein APCDD1-like (APCDD1L) OTP7CAV5 APCDL_HUMAN Decreases Expression [135]
LRRN4 C-terminal-like protein (LRRN4CL) OTJFDTVR LRN4L_HUMAN Increases Expression [135]
Phospholipid phosphatase 5 (PLPP5) OTHT51D6 PLPP5_HUMAN Decreases Expression [135]
Activin receptor type-1C (ACVR1C) OTOTYERF ACV1C_HUMAN Increases Expression [135]
Neuron navigator 1 (NAV1) OT667KTL NAV1_HUMAN Decreases Expression [135]
Nesprin-1 (SYNE1) OTSBSLUH SYNE1_HUMAN Decreases Expression [135]
Interleukin-17 receptor E (IL17RE) OTMFTNLS I17RE_HUMAN Increases Expression [135]
Neuroligin-2 (NLGN2) OTHDYL3H NLGN2_HUMAN Decreases Expression [135]
Tetraspanin-14 (TSPAN14) OT29167O TSN14_HUMAN Increases Expression [135]
LIM domain only protein 3 (LMO3) OTR7AJHN LMO3_HUMAN Increases Expression [135]
DEP domain-containing mTOR-interacting protein (DEPTOR) OTCBP1BT DPTOR_HUMAN Increases Expression [135]
Protein cornichon homolog 3 (CNIH3) OTNLZ2QS CNIH3_HUMAN Decreases Expression [135]
Ecto-NOX disulfide-thiol exchanger 1 (ENOX1) OT4WOLA8 ENOX1_HUMAN Decreases Expression [135]
Pyridoxal phosphate phosphatase PHOSPHO2 (PHOSPHO2) OTN3D4ZM PHOP2_HUMAN Increases Expression [135]
Melanocortin-2 receptor accessory protein (MRAP) OTLBWM7X MRAP_HUMAN Increases Expression [135]
Pleckstrin homology domain-containing family O member 2 (PLEKHO2) OT2FTK68 PKHO2_HUMAN Increases Expression [135]
G-protein coupled bile acid receptor 1 (GPBAR1) OT4BKEJ9 GPBAR_HUMAN Increases Expression [135]
Actin filament-associated protein 1-like 1 (AFAP1L1) OTWNTNDB AF1L1_HUMAN Increases Expression [135]
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 (ABHD5) OTY829Z3 ABHD5_HUMAN Increases Expression [135]
Cell migration-inducing and hyaluronan-binding protein (CEMIP) OTK80FYN CEMIP_HUMAN Decreases Expression [135]
Sodium-coupled neutral amino acid transporter 5 (SLC38A5) OTX4Q83J S38A5_HUMAN Decreases Expression [135]
Protein prune homolog 2 (PRUNE2) OTGW2974 PRUN2_HUMAN Increases Expression [135]
Coiled-coil domain-containing protein 107 (CCDC107) OTF1H2TM CC107_HUMAN Increases Expression [135]
RING finger protein 141 (RNF141) OT07ANSG RN141_HUMAN Increases Expression [135]
Palladin (PALLD) OTZ2MUJZ PALLD_HUMAN Increases Expression [135]
Gem-associated protein 6 (GEMIN6) OTE262KF GEMI6_HUMAN Increases Expression [135]
Nanos homolog 1 (NANOS1) OT3UNZZY NANO1_HUMAN Increases Expression [135]
Coiled-coil-helix-coiled-coil-helix domain-containing protein 10, mitochondrial (CHCHD10) OTCDHAM6 CHC10_HUMAN Increases Expression [135]
SHC-transforming protein 3 (SHC3) OT305NPA SHC3_HUMAN Increases Expression [135]
Nuclear receptor subfamily 4 group A member 3 (NR4A3) OTPBE9R1 NR4A3_HUMAN Increases Expression [135]
Receptor-type tyrosine-protein phosphatase U (PTPRU) OTHDO0QG PTPRU_HUMAN Decreases Expression [135]
Secreted frizzled-related protein 3 (FRZB) OTTO3DPY SFRP3_HUMAN Increases Expression [135]
Retinol dehydrogenase 5 (RDH5) OTYBZHCC RDH5_HUMAN Increases Expression [135]
NEDD4-binding protein 2-like 2 (N4BP2L2) OTV2F04G N42L2_HUMAN Decreases Expression [135]
Neuronal cell adhesion molecule (NRCAM) OT80HHQ2 NRCAM_HUMAN Increases Expression [135]
Protein tyrosine phosphatase type IVA 1 (PTP4A1) OTK0NFXJ TP4A1_HUMAN Decreases Expression [135]
Ribonuclease P/MRP protein subunit POP5 (POP5) OTCZTDJC POP5_HUMAN Increases Expression [135]
Protein TMEPAI (PMEPA1) OTY8Z9UF PMEPA_HUMAN Decreases Expression [135]
Protein lifeguard 3 (TMBIM1) OTE47B57 LFG3_HUMAN Increases Expression [135]
Antizyme inhibitor 2 (AZIN2) OT8OB7CG AZIN2_HUMAN Decreases Expression [135]
Fermitin family homolog 2 (FERMT2) OTZNPWWX FERM2_HUMAN Increases Expression [135]
Patatin-like phospholipase domain-containing protein 2 (PNPLA2) OTR3ERMR PLPL2_HUMAN Increases Expression [135]
SOSS complex subunit B2 (NABP1) OTFTNFHW SOSB2_HUMAN Increases Expression [135]
Mas-related G-protein coupled receptor member F (MRGPRF) OT74OZ2Z MRGRF_HUMAN Increases Expression [135]
Dapper homolog 3 (DACT3) OTSNQ55G DACT3_HUMAN Decreases Expression [135]
Inactive rhomboid protein 1 (RHBDF1) OTCQ7UDS RHDF1_HUMAN Decreases Expression [135]
Medium-chain acyl-CoA ligase ACSF2, mitochondrial (ACSF2) OTBB799S ACSF2_HUMAN Increases Expression [135]
Isochorismatase domain-containing protein 1 (ISOC1) OTAO7Z87 ISOC1_HUMAN Increases Expression [135]
Galectin-12 (LGALS12) OTNTQULB LEG12_HUMAN Increases Expression [135]
Transcription elongation factor A protein-like 4 (TCEAL4) OTX24CQI TCAL4_HUMAN Increases Expression [135]
C1GALT1-specific chaperone 1 (C1GALT1C1) OTRTZUF5 C1GLC_HUMAN Increases Expression [135]
Small integral membrane protein 12 (SMIM12) OTMOQSL4 SIM12_HUMAN Increases Expression [135]
Intraflagellar transport protein 43 homolog (IFT43) OTKWYQ5C IFT43_HUMAN Decreases Expression [135]
Kelch domain-containing protein 7B (KLHDC7B) OT2H5BNX KLD7B_HUMAN Decreases Expression [135]
Secreted frizzled-related protein 2 (SFRP2) OT8GZ0CA SFRP2_HUMAN Decreases Expression [135]
Receptor expression-enhancing protein 6 (REEP6) OTY4FPO8 REEP6_HUMAN Increases Expression [135]
Succinate--CoA ligase subunit beta, mitochondrial (SUCLG2) OT0KHLY2 SUCB2_HUMAN Increases Expression [135]
Calmin (CLMN) OT7U5J3T CLMN_HUMAN Increases Expression [135]
Bcl-2-modifying factor (BMF) OT90NSLI BMF_HUMAN Decreases Expression [135]
FYVE, RhoGEF and PH domain-containing protein 4 (FGD4) OTYXJQCW FGD4_HUMAN Increases Expression [135]
RIPOR family member 3 (RIPOR3) OTHZ4RKK RIPR3_HUMAN Increases Expression [135]
Pseudokinase FAM20A (FAM20A) OT5Z5IW8 FA20A_HUMAN Decreases Expression [135]
Prickle-like protein 1 (PRICKLE1) OT9HHEM9 PRIC1_HUMAN Decreases Expression [135]
Sterile alpha motif domain-containing protein 11 (SAMD11) OT6WRQOX SAM11_HUMAN Decreases Expression [135]
Diacylglycerol O-acyltransferase 2 (DGAT2) OTE5PDD0 DGAT2_HUMAN Increases Expression [135]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Decreases Expression [135]
Coiled-coil domain-containing protein 85A (CCDC85A) OT2GLF5Z CC85A_HUMAN Increases Expression [135]
Tribbles homolog 3 (TRIB3) OTG5OS7X TRIB3_HUMAN Decreases Expression [135]
Hemicentin-1 (HMCN1) OTLZAS0P HMCN1_HUMAN Decreases Expression [135]
Ethanolamine-phosphate cytidylyltransferase (PCYT2) OTT8TAEA PCY2_HUMAN Increases Expression [135]
Sphingosine 1-phosphate receptor 3 (S1PR3) OTXBIYO8 S1PR3_HUMAN Increases Expression [135]
Sortilin (SORT1) OTFCQ4B1 SORT_HUMAN Increases Expression [135]
Perilipin-2 (PLIN2) OTRXJ9UN PLIN2_HUMAN Increases Expression [135]
Monoglyceride lipase (MGLL) OT5ES4IE MGLL_HUMAN Increases Expression [135]
Collagen alpha-1(XII) chain (COL12A1) OTHLTV53 COCA1_HUMAN Decreases Expression [135]
Metalloproteinase inhibitor 4 (TIMP4) OT8A68SW TIMP4_HUMAN Increases Expression [135]
MyoD family inhibitor (MDFI) OTIA6YUG MDFI_HUMAN Decreases Expression [135]
Paired mesoderm homeobox protein 2 (PRRX2) OT8UR4AU PRRX2_HUMAN Decreases Expression [135]
Protein smoothened (SMO) OTXXE208 SMO_HUMAN Decreases Expression [135]
Histone H2A type 1-J (H2AC14) OT5Y4MMC H2A1J_HUMAN Increases Expression [135]
Retinoic acid receptor responder protein 2 (RARRES2) OT1BJE8K RARR2_HUMAN Decreases Expression [135]
Growth/differentiation factor 15 (GDF15) OTWQN50N GDF15_HUMAN Decreases Expression [135]
FYVE and coiled-coil domain-containing protein 1 (FYCO1) OTKZHTZ5 FYCO1_HUMAN Increases Expression [135]
Calsyntenin-3 (CLSTN3) OTPUFK4C CSTN3_HUMAN Decreases Expression [135]
Ferroptosis suppressor protein 1 (AIFM2) OT57XWXO FSP1_HUMAN Increases Expression [135]
La-related protein 6 (LARP6) OTUQ9QS9 LARP6_HUMAN Decreases Expression [135]
Peroxiredoxin-like 2A (PRXL2A) OTR4X7UH PXL2A_HUMAN Increases Expression [135]
Latexin (LXN) OTZQ2M6Y LXN_HUMAN Decreases Expression [135]
Transmembrane protein 204 (TMEM204) OT7X11D9 TM204_HUMAN Decreases Expression [135]
Histone H2A.J (H2AJ) OTVA4XTW H2AJ_HUMAN Increases Expression [135]
Chordin-like protein 1 (CHRDL1) OTGMWVVA CRDL1_HUMAN Increases Expression [135]
Protein ABHD14A (ABHD14A) OT94GKE1 ABHEA_HUMAN Increases Expression [135]
Coiled-coil-helix-coiled-coil-helix domain-containing protein 7 (CHCHD7) OTHHROAQ CHCH7_HUMAN Increases Expression [135]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) OTJGE772 CHAC1_HUMAN Decreases Expression [135]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) OTZ092ZJ THIC_HUMAN Increases Expression [135]
Sorbin and SH3 domain-containing protein 1 (SORBS1) OTWH8762 SRBS1_HUMAN Increases Expression [135]
Oxysterol-binding protein-related protein 10 (OSBPL10) OT0TFMBE OSB10_HUMAN Decreases Expression [135]
EMILIN-2 (EMILIN2) OTOYK5A8 EMIL2_HUMAN Increases Expression [135]
RanBP-type and C3HC4-type zinc finger-containing protein 1 (RBCK1) OTOOXC7B HOIL1_HUMAN Decreases Expression [135]
Protein Niban 1 (NIBAN1) OTYOLI12 NIBA1_HUMAN Decreases Expression [135]
Forkhead box protein Q1 (FOXQ1) OT6S3EB0 FOXQ1_HUMAN Decreases Expression [135]
Carbohydrate sulfotransferase 6 (CHST6) OTXD2IWK CHST6_HUMAN Decreases Expression [135]
N-alpha-acetyltransferase 50 (NAA50) OTFJ8S47 NAA50_HUMAN Increases Expression [135]
Serine/threonine-protein kinase SIK2 (SIK2) OTODY7XG SIK2_HUMAN Increases Expression [135]
Uncharacterized protein C1orf21 (C1ORF21) OTMD7O88 CA021_HUMAN Increases Expression [135]
Solute carrier family 25 member 32 (SLC25A32) OTPP3NWG S2532_HUMAN Increases Expression [135]
Ras association domain-containing protein 4 (RASSF4) OT7YLOFH RASF4_HUMAN Increases Expression [135]
Forkhead box protein P1 (FOXP1) OTSG6XGF FOXP1_HUMAN Decreases Expression [135]
SPARC-related modular calcium-binding protein 2 (SMOC2) OTK1EQ49 SMOC2_HUMAN Increases Expression [135]
Serine/threonine-protein kinase PLK3 (PLK3) OT19CT2Z PLK3_HUMAN Decreases Expression [135]
Regulator of cell cycle RGCC (RGCC) OTYJMLWM RGCC_HUMAN Increases Expression [135]
Very long chain fatty acid elongase 6 (ELOVL6) OTB26UJJ ELOV6_HUMAN Increases Expression [135]
IGF-like family receptor 1 (IGFLR1) OTPUCWQR IGFR1_HUMAN Increases Expression [135]
Reticulophagy regulator 1 (RETREG1) OTYOSLZX RETR1_HUMAN Increases Expression [135]
Anthrax toxin receptor 1 (ANTXR1) OT5W1GPC ANTR1_HUMAN Decreases Expression [135]
Gremlin-2 (GREM2) OTE91EWT GREM2_HUMAN Decreases Expression [135]
Protein eva-1 homolog A (EVA1A) OTCY3Q2M EVA1A_HUMAN Decreases Expression [135]
RING finger protein 122 (RNF122) OT8RE3IM RN122_HUMAN Decreases Expression [135]
Interleukin-21 receptor (IL21R) OTDIOB63 IL21R_HUMAN Decreases Expression [135]
MAP kinase-interacting serine/threonine-protein kinase 2 (MKNK2) OTNA9G8V MKNK2_HUMAN Increases Expression [135]
Mitochondrial thiamine pyrophosphate carrier (SLC25A19) OT157TY3 TPC_HUMAN Increases Expression [135]
Glycerol-3-phosphate acyltransferase 1, mitochondrial (GPAM) OTR1XD9B GPAT1_HUMAN Increases Expression [135]
Plexin-A4 (PLXNA4) OT5XKB3Q PLXA4_HUMAN Increases Expression [135]
Solute carrier family 40 member 1 (SLC40A1) OT8RV2VY S40A1_HUMAN Increases Expression [135]
Carbohydrate-responsive element-binding protein (MLXIPL) OTR9MLLW MLXPL_HUMAN Increases Expression [135]
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A) OT5V52LN TNR12_HUMAN Decreases Expression [135]
G-protein coupled receptor family C group 5 member C (GPRC5C) OT45AJT3 GPC5C_HUMAN Decreases Expression [135]
Omega-amidase NIT2 (NIT2) OTC1RAH3 NIT2_HUMAN Increases Expression [135]
PDZ and LIM domain protein 7 (PDLIM7) OTAZVODU PDLI7_HUMAN Decreases Expression [135]
Acetyl-coenzyme A synthetase, cytoplasmic (ACSS2) OTB1FZJU ACSA_HUMAN Increases Expression [135]
Sialin (SLC17A5) OTM5EC0O S17A5_HUMAN Increases Expression [135]
Teashirt homolog 2 (TSHZ2) OTZWBXXY TSH2_HUMAN Decreases Expression [135]
NADH dehydrogenase 1 alpha subcomplex subunit 4-like 2 (NDUFA4L2) OTK0PG7R NUA4L_HUMAN Decreases Expression [135]
1-acyl-sn-glycerol-3-phosphate acyltransferase delta (AGPAT4) OT5CTQKO PLCD_HUMAN Decreases Expression [135]
Semaphorin-3G (SEMA3G) OTBLVF8V SEM3G_HUMAN Increases Expression [135]
Protein C19orf12 (C19ORF12) OTVSJ1AR CS012_HUMAN Increases Expression [135]
Teneurin-2 (TENM2) OTPLUYEF TEN2_HUMAN Decreases Expression [135]
Protein DEPP1 (DEPP1) OTB36PHJ DEPP1_HUMAN Increases Expression [135]
Copper homeostasis protein cutC homolog (CUTC) OTOVHLU9 CUTC_HUMAN Increases Expression [135]
PI-PLC X domain-containing protein 1 (PLCXD1) OTU7KCQL PLCX1_HUMAN Increases Expression [135]
Fas apoptotic inhibitory molecule 1 (FAIM) OTR67PGU FAIM1_HUMAN Increases Expression [135]
Spermine oxidase (SMOX) OT11E62Y SMOX_HUMAN Decreases Expression [135]
DNA damage-inducible transcript 4 protein (DDIT4) OTHY8SY4 DDIT4_HUMAN Decreases Expression [135]
Myotubularin-related protein 10 (MTMR10) OTF6DB4O MTMRA_HUMAN Increases Expression [135]
Dapper homolog 1 (DACT1) OT19Z704 DACT1_HUMAN Decreases Expression [135]
Very long chain fatty acid elongase 5 (ELOVL5) OT375W1Z ELOV5_HUMAN Increases Expression [135]
Serine/threonine-protein kinase PLK2 (PLK2) OTKMJXJ8 PLK2_HUMAN Decreases Expression [135]
Potassium voltage-gated channel subfamily D member 2 (KCND2) OTIFUVV7 KCND2_HUMAN Decreases Expression [135]
Ankycorbin (RAI14) OT6USGBK RAI14_HUMAN Decreases Expression [135]
Neurotrimin (NTM) OTHF0UQU NTRI_HUMAN Decreases Expression [135]
Rho GTPase-activating protein 20 (ARHGAP20) OTG1STV8 RHG20_HUMAN Increases Expression [135]
Signal-induced proliferation-associated 1-like protein 2 (SIPA1L2) OT8NJE5D SI1L2_HUMAN Decreases Expression [135]
]-phosphatase 2, mitochondrial (PDP2) OTADNMGK PDP2_HUMAN Increases Expression [135]
A disintegrin and metalloproteinase with thrombospondin motifs 9 (ADAMTS9) OTV3Q0DS ATS9_HUMAN Increases Expression [135]
Dolichol-phosphate mannosyltransferase subunit 3 (DPM3) OTSB4XO0 DPM3_HUMAN Increases Expression [135]
SUMO-activating enzyme subunit 1 (SAE1) OT18HFX5 SAE1_HUMAN Decreases Expression [135]
C-type mannose receptor 2 (MRC2) OTLWQAX1 MRC2_HUMAN Decreases Expression [135]
ATP-binding cassette sub-family D member 2 (ABCD2) OT8RGNH8 ABCD2_HUMAN Increases Expression [135]
Copine-7 (CPNE7) OTR0FJ8A CPNE7_HUMAN Increases Expression [135]
Tumor necrosis factor receptor superfamily member 10D (TNFRSF10D) OTOSRDJT TR10D_HUMAN Decreases Expression [135]
Heat shock protein beta-7 (HSPB7) OTLATAOV HSPB7_HUMAN Increases Expression [135]
Tight junction protein ZO-2 (TJP2) OTQUY6BV ZO2_HUMAN Increases Expression [135]
Gamma-adducin (ADD3) OTDRSHAZ ADDG_HUMAN Increases Expression [135]
5'-AMP-activated protein kinase subunit gamma-2 (PRKAG2) OTHTAM54 AAKG2_HUMAN Increases Expression [135]
Solute carrier family 2, facilitated glucose transporter member 6 (SLC2A6) OTVUZCLG GTR6_HUMAN Increases Expression [135]
Sushi domain-containing protein 2 (SUSD2) OTSJTAZP SUSD2_HUMAN Increases Expression [135]
Zinc finger transcription factor Trps1 (TRPS1) OT7XPPEL TRPS1_HUMAN Decreases Expression [135]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Increases Expression [135]
Potassium voltage-gated channel subfamily G member 1 (KCNG1) OTZ9ZRG8 KCNG1_HUMAN Decreases Expression [135]
ERBB receptor feedback inhibitor 1 (ERRFI1) OT7VZ2IZ ERRFI_HUMAN Increases Expression [135]
A-kinase anchor protein 11 (AKAP11) OT7E2FVD AKA11_HUMAN Decreases Expression [135]
A disintegrin and metalloproteinase with thrombospondin motifs 6 (ADAMTS6) OTSZE6L4 ATS6_HUMAN Decreases Expression [135]
Integrin alpha-11 (ITGA11) OTBWSRA1 ITA11_HUMAN Decreases Expression [135]
Long-chain-fatty-acid--CoA ligase 5 (ACSL5) OT3L9XO3 ACSL5_HUMAN Increases Expression [135]
Frizzled-4 (FZD4) OTGLZIE0 FZD4_HUMAN Increases Expression [135]
RING finger protein 112 (RNF112) OT0Q9OUQ RN112_HUMAN Decreases Expression [135]
Synaptopodin-2 (SYNPO2) OTC3U0YH SYNP2_HUMAN Increases Expression [135]
Protein NDRG2 (NDRG2) OT5L6KD7 NDRG2_HUMAN Increases Expression [135]
Endothelial protein C receptor (PROCR) OTRHED17 EPCR_HUMAN Increases Expression [135]
Protein phosphatase 1 regulatory subunit 3C (PPP1R3C) OTEU05TX PPR3C_HUMAN Decreases Expression [135]
HIG1 domain family member 1A, mitochondrial (HIGD1A) OTS351DV HIG1A_HUMAN Increases Expression [135]
Dexamethasone-induced Ras-related protein 1 (RASD1) OT2BAJHK RASD1_HUMAN Increases Expression [135]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5) OT03QCLM ATF5_HUMAN Decreases Expression [135]
Kelch-like protein 20 (KLHL20) OTC0SFS9 KLH20_HUMAN Increases Expression [135]
Calcium-regulated heat-stable protein 1 (CARHSP1) OTAUG6Y9 CHSP1_HUMAN Decreases Expression [135]
Deoxyribose-phosphate aldolase (DERA) OT8SMO3N DEOC_HUMAN Increases Expression [135]
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (SAMHD1) OTBCIBC7 SAMH1_HUMAN Increases Expression [135]
C2 domain-containing protein 2 (C2CD2) OTL1K0OB C2CD2_HUMAN Increases Expression [135]
Lysyl oxidase homolog 2 (LOXL2) OTRT46B5 LOXL2_HUMAN Decreases Expression [135]
ADP-ribose glycohydrolase OARD1 (OARD1) OTNNWATS OARD1_HUMAN Decreases Expression [135]
Ankyrin repeat and SOCS box protein 1 (ASB1) OT0NZGEI ASB1_HUMAN Decreases Expression [135]
Mitochondrial import inner membrane translocase subunit Tim8 B (TIMM8B) OTGZO1MT TIM8B_HUMAN Increases Expression [135]
Retinoic acid-induced protein 2 (RAI2) OTR8LX4J RAI2_HUMAN Increases Expression [135]
Mitochondrial pyruvate carrier 1 (MPC1) OT6DYFUO MPC1_HUMAN Increases Expression [135]
Melanoma-associated antigen D1 (MAGED1) OT6EOLFC MAGD1_HUMAN Decreases Expression [135]
Cysteine sulfinic acid decarboxylase (CSAD) OT3I2G0A CSAD_HUMAN Increases Expression [135]
Glypican-6 (GPC6) OTNJBESF GPC6_HUMAN Decreases Expression [135]
Inositol 1,4,5-triphosphate receptor associated 1 (IRAG1) OTMRW5U5 IRAG1_HUMAN Increases Expression [135]
Sulfide:quinone oxidoreductase, mitochondrial (SQOR) OTTLD0KB SQOR_HUMAN Increases Expression [135]
SET-binding protein (SETBP1) OTKGCOSR SETBP_HUMAN Decreases Expression [135]
Tryptophan 2,3-dioxygenase (TDO2) OTV5HKJ4 T23O_HUMAN Increases Expression [178]
Serum paraoxonase/arylesterase 1 (PON1) OTD0Z2XO PON1_HUMAN Increases Expression [179]
Collagen alpha-1(II) chain (COL2A1) OT5E59C8 CO2A1_HUMAN Decreases Expression [180]
Alkaline phosphatase, tissue-nonspecific isozyme (ALPL) OTG7J4BP PPBT_HUMAN Increases Expression [180]
Aggrecan core protein (ACAN) OTUOCW8K PGCA_HUMAN Decreases Expression [180]
Transcription factor SOX-9 (SOX9) OTVDJFGN SOX9_HUMAN Decreases Expression [180]
Collagen alpha-1(X) chain (COL10A1) OTC4G2YC COAA1_HUMAN Increases Expression [180]
Indian hedgehog protein (IHH) OT1DWGXC IHH_HUMAN Increases Expression [180]
Glutathione S-transferase A1 (GSTA1) OTA7K5XA GSTA1_HUMAN Increases Expression [181]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) OTQ4W7MT TR11B_HUMAN Decreases Expression [182]
Basic helix-loop-helix ARNT-like protein 1 (BMAL1) OTMI12L2 BMAL1_HUMAN Affects Expression [183]
Syntenin-1 (SDCBP) OTS3NCC5 SDCB1_HUMAN Increases Expression [139]
Transcription factor SOX-1 (SOX1) OTVI1RAR SOX1_HUMAN Increases Expression [184]
Proepiregulin (EREG) OTRM4NQY EREG_HUMAN Increases Expression [185]
Calsequestrin-2 (CASQ2) OT09MNQ8 CASQ2_HUMAN Affects Expression [184]
Period circadian protein homolog 2 (PER2) OTU2B1DJ PER2_HUMAN Affects Expression [183]
Solute carrier family 22 member 1 (SLC22A1) OT7817I4 S22A1_HUMAN Increases Expression [186]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Affects Expression [187]
Transmembrane protease serine 2 (TMPRSS2) OTN44YQ5 TMPS2_HUMAN Increases Expression [48]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Expression [188]
Toll-like receptor 3 (TLR3) OT8QPYXZ TLR3_HUMAN Decreases Expression [189]
Circadian locomoter output cycles protein kaput (CLOCK) OTNEOJY7 CLOCK_HUMAN Affects Expression [183]
Suppressor of cytokine signaling 1 (SOCS1) OTWA9KFU SOCS1_HUMAN Increases Expression [189]
SLIT-ROBO Rho GTPase-activating protein 3 (SRGAP3) OT9ZS72C SRGP3_HUMAN Increases Expression [190]
Carbonic anhydrase 12 (CA12) OT6WNFU8 CAH12_HUMAN Increases Expression [140]
Neuronal migration protein doublecortin (DCX) OTISR7K3 DCX_HUMAN Increases Expression [184]
Glucose-6-phosphate exchanger SLC37A4 (SLC37A4) OTLCYA32 G6PT1_HUMAN Increases Expression [191]
Left-right determination factor 1 (LEFTY1) OT51HVC4 LFTY1_HUMAN Increases Expression [140]
Dickkopf-related protein 1 (DKK1) OTRDLUSP DKK1_HUMAN Increases Expression [192]
Sciellin (SCEL) OT46SDNQ SCEL_HUMAN Increases Expression [139]
Homeobox protein SIX3 (SIX3) OTP5E3VU SIX3_HUMAN Increases Expression [184]
Transforming acidic coiled-coil-containing protein 2 (TACC2) OTW4M7HI TACC2_HUMAN Increases Expression [193]
Eyes absent homolog 4 (EYA4) OTINGR3Z EYA4_HUMAN Affects Expression [184]
Interleukin-33 (IL33) OTT5YWK3 IL33_HUMAN Decreases Expression [194]
Claudin-1 (CLDN1) OT27KV99 CLD1_HUMAN Increases Expression [136]
Eomesodermin homolog (EOMES) OTB9VQFA EOMES_HUMAN Increases Expression [184]
T-box transcription factor TBX6 (TBX6) OTW1Q8RM TBX6_HUMAN Affects Expression [184]
Prothrombin (F2) OTNFSM49 THRB_HUMAN Affects Expression [184]
Renin (REN) OT52GZR2 RENI_HUMAN Increases Activity [195]
2'-5'-oligoadenylate synthase 1 (OAS1) OT8ZLOCY OAS1_HUMAN Decreases Expression [196]
Alpha-1-antitrypsin (SERPINA1) OTACYW9J A1AT_HUMAN Decreases Expression [197]
Low-density lipoprotein receptor (LDLR) OTH559LU LDLR_HUMAN Decreases Expression [198]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Decreases Expression [199]
Pro-opiomelanocortin (POMC) OTV41F7T COLI_HUMAN Decreases Expression [195]
Prolactin (PRL) OTWFQGX7 PRL_HUMAN Increases Expression [200]
Insulin (INS) OTZ85PDU INS_HUMAN Decreases Response To Substance [201]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Decreases Expression [202]
Interferon gamma (IFNG) OTXG9JM7 IFNG_HUMAN Decreases Expression [155]
Interleukin-2 receptor subunit alpha (IL2RA) OT0MWCHG IL2RA_HUMAN Decreases Expression [203]
T-cell surface glycoprotein CD4 (CD4) OT7Z5LNF CD4_HUMAN Decreases Expression [204]
HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) OT7KZMP2 DRA_HUMAN Increases Expression [189]
HLA class II histocompatibility antigen, DQ alpha 1 chain (HLA-DQA1) OTC6GISG DQA1_HUMAN Increases Expression [189]
HLA class II histocompatibility antigen, DRB1 beta chain (HLA-DRB1) OTRGGIFP DRB1_HUMAN Decreases Expression [205]
HLA class II histocompatibility antigen, DQ beta 1 chain (HLA-DQB1) OTVVI3UI DQB1_HUMAN Affects Expression [189]
Alpha-crystallin B chain (CRYAB) OTY4JGYU CRYAB_HUMAN Increases Expression [206]
Albumin (ALB) OTVMM513 ALBU_HUMAN Decreases Expression [197]
Annexin A1 (ANXA1) OT5OFDJC ANXA1_HUMAN Increases Expression [207]
Granulocyte-macrophage colony-stimulating factor (CSF2) OT1M7D28 CSF2_HUMAN Decreases Expression [155]
HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1) OTW8JHU2 DPB1_HUMAN Increases Expression [189]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Decreases Expression [208]
Metallothionein-1E (MT1E) OTXJKU4Y MT1E_HUMAN Increases Expression [139]
Insulin-like growth factor I (IGF1) OTIIZR61 IGF1_HUMAN Decreases Expression [209]
Protein S100-A8 (S100A8) OTVMOB3F S10A8_HUMAN Increases Expression [210]
Interleukin-5 (IL5) OTAFPSCO IL5_HUMAN Decreases Expression [155]
Plasminogen activator inhibitor 1 (SERPINE1) OTT0MPQ3 PAI1_HUMAN Increases Expression [211]
Myeloperoxidase (MPO) OTOOXLIN PERM_HUMAN Affects Expression [184]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Decreases Expression [138]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Increases Phosphorylation [212]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Increases Expression [190]
Protein S100-A9 (S100A9) OTOARHCS S10A9_HUMAN Increases Expression [210]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Increases Expression [213]
Heat shock protein HSP 90-alpha (HSP90AA1) OTLG1WPK HS90A_HUMAN Increases Expression [206]
Tyrosine-protein kinase Lyn (LYN) OTP686K2 LYN_HUMAN Affects Expression [189]
Beta-microseminoprotein (MSMB) OTYORAJC MSMB_HUMAN Increases Expression [140]
Corticosteroid-binding globulin (SERPINA6) OTOIBEW7 CBG_HUMAN Increases Expression [214]
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Decreases Expression [136]
Monocyte differentiation antigen CD14 (CD14) OT83GJ47 CD14_HUMAN Increases Expression [215]
Receptor-type tyrosine-protein phosphatase C (PTPRC) OT6KOR77 PTPRC_HUMAN Affects Expression [184]
Interleukin-3 (IL3) OT0CQ35N IL3_HUMAN Decreases Expression [155]
Interleukin-6 receptor subunit alpha (IL6R) OTCQL07Z IL6RA_HUMAN Increases Expression [216]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [217]
Granulocyte colony-stimulating factor (CSF3) OT9GC6TP CSF3_HUMAN Increases Expression [139]
Transmembrane protein 191B (TMEM191B) OTDKHB0K T191B_HUMAN Decreases Expression [140]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Decreases Expression [218]
Transcriptional activator Myb (MYB) OTJH64IV MYB_HUMAN Increases Expression [139]
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Decreases Expression [209]
Transforming growth factor beta-3 proprotein (TGFB3) OT2LOUQ1 TGFB3_HUMAN Increases Expression [139]
Phenylethanolamine N-methyltransferase (PNMT) OTGLCPE8 PNMT_HUMAN Increases Expression [140]
DNA topoisomerase 2-alpha (TOP2A) OT6LPS08 TOP2A_HUMAN Increases Expression [190]
Pulmonary surfactant-associated protein C (SFTPC) OTIZJD09 PSPC_HUMAN Increases Expression [219]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Decreases Expression [220]
Parathyroid hormone-related protein (PTHLH) OTI1JF13 PTHR_HUMAN Decreases Expression [221]
Myosin-7 (MYH7) OT4Z9T8N MYH7_HUMAN Increases Expression [184]
Myosin-6 (MYH6) OT3YNCH1 MYH6_HUMAN Affects Expression [184]
Metallothionein-1G (MT1G) OTAV1OCR MT1G_HUMAN Increases Expression [139]
Tissue factor (F3) OT3MSU3B TF_HUMAN Increases Expression [222]
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Increases Expression [192]
Hepatocyte growth factor (HGF) OTGHUA23 HGF_HUMAN Decreases Expression [223]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Increases Expression [190]
Interleukin-2 receptor subunit beta (IL2RB) OT6M0F70 IL2RB_HUMAN Decreases Expression [203]
Protein C-ets-2 (ETS2) OTPVHOZ7 ETS2_HUMAN Increases Expression [189]
Mucin-1 (MUC1) OTHQI7IY MUC1_HUMAN Increases Expression [224]
Cyclic AMP-responsive element-binding protein 1 (CREB1) OT1MDLA1 CREB1_HUMAN Increases Phosphorylation [225]
Methylated-DNA--protein-cysteine methyltransferase (MGMT) OT40A9WH MGMT_HUMAN Increases Expression [226]
Protein kinase C alpha type (PRKCA) OT5UWNRD KPCA_HUMAN Affects Expression [189]
Syndecan-1 (SDC1) OTWKRVZC SDC1_HUMAN Decreases Expression [227]
Transcobalamin-2 (TCN2) OT41D0L3 TCO2_HUMAN Decreases Expression [189]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Increases Expression [190]
Nuclear receptor subfamily 1 group D member 1 (NR1D1) OTJ38PTB NR1D1_HUMAN Decreases Expression [228]
fMet-Leu-Phe receptor (FPR1) OTFF9I6W FPR1_HUMAN Increases Expression [208]
C-type natriuretic peptide (NPPC) OTYJ0LMA ANFC_HUMAN Increases Expression [140]
Paired box protein Pax-3 (PAX3) OTN5PJZV PAX3_HUMAN Affects Expression [184]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [192]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Decreases Expression [229]
Alpha-1D adrenergic receptor (ADRA1D) OTW2CD1O ADA1D_HUMAN Increases Expression [230]
Proteinase-activated receptor 1 (F2R) OT4WVWBO PAR1_HUMAN Increases Expression [231]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Increases Expression [232]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Increases Expression [189]
Paired box protein Pax-6 (PAX6) OTOC9876 PAX6_HUMAN Increases Expression [184]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Activity [233]
Interleukin-1 receptor type 2 (IL1R2) OT0G7E35 IL1R2_HUMAN Increases Expression [205]
Proteasome subunit beta type-9 (PSMB9) OTFV57T8 PSB9_HUMAN Decreases Expression [196]
HLA class II histocompatibility antigen, DM beta chain (HLA-DMB) OT17HGXJ DMB_HUMAN Decreases Expression [234]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Activity [233]
Dual specificity protein phosphatase 1 (DUSP1) OTN6BR75 DUS1_HUMAN Increases Expression [139]
G1/S-specific cyclin-D2 (CCND2) OTDULQF9 CCND2_HUMAN Decreases Expression [235]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Phosphorylation [236]
Macrosialin (CD68) OTOYEY3J CD68_HUMAN Increases Expression [215]
Alpha-1B adrenergic receptor (ADRA1B) OTSAYAFD ADA1B_HUMAN Increases Expression [230]
Insulin receptor substrate 1 (IRS1) OTNO82CU IRS1_HUMAN Decreases Expression [194]
Glucose-6-phosphatase catalytic subunit 1 (G6PC1) OTJ6FM9F G6PC1_HUMAN Decreases Expression [214]
Chitinase-3-like protein 1 (CHI3L1) OT2Z7VJH CH3L1_HUMAN Decreases Expression [237]
Receptor-type tyrosine-protein kinase FLT3 (FLT3) OTMSRYMK FLT3_HUMAN Affects Expression [184]
GMP reductase 1 (GMPR) OTERWHYM GMPR1_HUMAN Increases Expression [140]
TGF-beta receptor type-2 (TGFBR2) OT3P7GZP TGFR2_HUMAN Increases Expression [189]
Peroxisome proliferator-activated receptor gamma (PPARG) OTHMARHO PPARG_HUMAN Increases Expression [238]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [200]
Interleukin-15 (IL15) OTQSYWQS IL15_HUMAN Increases Expression [139]
Leptin (LEP) OT5Q7ODW LEP_HUMAN Increases Expression [239]
Signal transducer and activator of transcription 5A (STAT5A) OTBSJGN3 STA5A_HUMAN Affects Activity [240]
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA) OTTOMI8J PK3CA_HUMAN Affects Expression [156]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Decreases Activity [241]
Interleukin-12 receptor subunit beta-1 (IL12RB1) OTM1IJO2 I12R1_HUMAN Decreases Expression [242]
Nuclear receptor subfamily 4 group A member 2 (NR4A2) OT3F9IR2 NR4A2_HUMAN Increases Expression [184]
Transcription factor GATA-4 (GATA4) OTQHWAZG GATA4_HUMAN Increases Expression [184]
Mitogen-activated protein kinase 8 (MAPK8) OTEREYS5 MK08_HUMAN Affects Expression [156]
Proliferation marker protein Ki-67 (MKI67) OTA8N1QI KI67_HUMAN Decreases Expression [192]
5-hydroxytryptamine receptor 3A (HTR3A) OTAIV1AK 5HT3A_HUMAN Decreases Activity [243]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Decreases Expression [244]
Dual specificity mitogen-activated protein kinase kinase 3 (MAP2K3) OTI2OREX MP2K3_HUMAN Increases Expression [245]
Tumor necrosis factor ligand superfamily member 6 (FASLG) OTZARCHH TNFL6_HUMAN Decreases Expression [246]
G protein-activated inward rectifier potassium channel 4 (KCNJ5) OTA2MBIE KCNJ5_HUMAN Affects Expression [184]
Nestin (NES) OTZ9PZ14 NEST_HUMAN Increases Expression [184]
Sodium/hydrogen exchanger 3 (SLC9A3) OTZ7PFVT SL9A3_HUMAN Increases Expression [247]
Steroidogenic acute regulatory protein, mitochondrial (STAR) OTFEZ5AI STAR_HUMAN Decreases Expression [248]
CCAAT/enhancer-binding protein alpha (CEBPA) OTOM9OE4 CEBPA_HUMAN Increases Expression [249]
Cyclin-dependent kinase inhibitor 1C (CDKN1C) OTASTJ3Q CDN1C_HUMAN Increases Expression [200]
Amiloride-sensitive sodium channel subunit beta (SCNN1B) OT61QQTL SCNNB_HUMAN Increases Expression [250]
Amiloride-sensitive sodium channel subunit gamma (SCNN1G) OTSJYQVQ SCNNG_HUMAN Increases Expression [250]
C-C chemokine receptor type 3 (CCR3) OT6GBUFA CCR3_HUMAN Decreases Expression [251]
Signal transducer and activator of transcription 5B (STAT5B) OTZVPEBT STA5B_HUMAN Increases Activity [240]
cAMP-dependent protein kinase catalytic subunit PRKX (PRKX) OTDAC6Z0 PRKX_HUMAN Increases Expression [139]
Thyroxine 5-deiodinase (DIO3) OTNTITOT IOD3_HUMAN Decreases Activity [252]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Activity [253]
Transcription factor SOX-10 (SOX10) OTF25ULQ SOX10_HUMAN Increases Expression [184]
Forkhead box protein L2 (FOXL2) OTFRQUYL FOXL2_HUMAN Decreases Expression [244]
Interleukin-2 (IL2) OTGI4NSA IL2_HUMAN Decreases Expression [254]
C-X-C chemokine receptor type 4 (CXCR4) OTUFSBX2 CXCR4_HUMAN Increases Expression [255]
Beta-2-microglobulin (B2M) OTDWN6NX B2MG_HUMAN Decreases Expression [256]
Transforming growth factor beta-2 proprotein (TGFB2) OTC0TXEP TGFB2_HUMAN Decreases Expression [199]
Histone H3.1 (H3C1) OTGBGOZW H31_HUMAN Increases Expression [190]
Heat shock factor protein 1 (HSF1) OTYNJ4KP HSF1_HUMAN Increases Activity [257]
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) OTLQN1E2 HNRPU_HUMAN Affects Localization [258]
DNA-binding protein inhibitor ID-2 (ID2) OT0U1D53 ID2_HUMAN Decreases Expression [192]
Paired box protein Pax-5 (PAX5) OTYBJJWX PAX5_HUMAN Affects Expression [184]
Urokinase plasminogen activator surface receptor (PLAUR) OTIRKKEQ UPAR_HUMAN Decreases Expression [189]
Elongation factor 1-alpha 2 (EEF1A2) OT9Z23K5 EF1A2_HUMAN Increases Expression [139]
Homeobox protein engrailed-1 (EN1) OT2DKIDK HME1_HUMAN Increases Expression [184]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Increases Expression [259]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Increases Expression [139]
Steroidogenic factor 1 (NR5A1) OTOULYR4 STF1_HUMAN Decreases Expression [248]
Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5) OT404F9K FKBP5_HUMAN Increases Expression [189]
Sequestosome-1 (SQSTM1) OTGY5D5J SQSTM_HUMAN Decreases Expression [220]
Spectrin alpha chain, non-erythrocytic 1 (SPTAN1) OT6VY3A3 SPTN1_HUMAN Increases Cleavage [236]
Inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) OTX7MWW1 ITPR1_HUMAN Increases Expression [190]
Receptor tyrosine-protein kinase erbB-4 (ERBB4) OT9L6C41 ERBB4_HUMAN Increases Expression [139]
Mitogen-activated protein kinase 14 (MAPK14) OT5TCO3O MK14_HUMAN Increases Activity [260]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [235]
Leukotriene C4 synthase (LTC4S) OT3XNFJZ LTC4S_HUMAN Increases Expression [261]
Protein Largen (PRR16) OTG4TEGR LARGN_HUMAN Increases Expression [140]
Zinc finger protein PLAG1 (PLAG1) OTT9AJQY PLAG1_HUMAN Increases Expression [139]
Beclin 1-associated autophagy-related key regulator (ATG14) OTPZDKI0 BAKOR_HUMAN Increases Expression [220]
Histone H3.2 (H3C13) OT97FS6C H32_HUMAN Increases Expression [190]
Cytochrome P450 4Z1 (CYP4Z1) OTKRGJBG CP4Z1_HUMAN Increases Expression [262]
Secreted frizzled-related protein 1 (SFRP1) OT0U9G41 SFRP1_HUMAN Increases Expression [139]
ATP-dependent RNA helicase TDRD9 (TDRD9) OTS4UBI8 TDRD9_HUMAN Increases Expression [140]
Microprocessor complex subunit DGCR8 (DGCR8) OT62LXE4 DGCR8_HUMAN Increases Expression [198]
Aquaporin-3 (AQP3) OT2J7JPD AQP3_HUMAN Increases Expression [263]
Estrogen receptor beta (ESR2) OTXNR2WQ ESR2_HUMAN Increases Expression [194]
Ras-responsive element-binding protein 1 (RREB1) OT62460U RREB1_HUMAN Increases Expression [139]
Hyaluronan synthase 2 (HAS2) OTTD3PAL HYAS2_HUMAN Decreases Expression [264]
Neurogenin-1 (NEUROG1) OTMJZP9G NGN1_HUMAN Decreases Expression [140]
Paired mesoderm homeobox protein 2B (PHOX2B) OT3SFR2O PHX2B_HUMAN Affects Expression [184]
Interleukin-12 receptor subunit beta-2 (IL12RB2) OTDLV8H8 I12R2_HUMAN Decreases Expression [242]
Cbp/p300-interacting transactivator 1 (CITED1) OTUJQ3VL CITE1_HUMAN Decreases Expression [184]
Myocilin (MYOC) OT6DAHNF MYOC_HUMAN Increases Expression [206]
Mesoderm posterior protein 1 (MESP1) OTY5QDBN MESP1_HUMAN Decreases Expression [184]
Chitinase domain-containing protein 1 (CHID1) OT4DIUKC CHID1_HUMAN Increases Expression [237]
Angiotensin-converting enzyme 2 (ACE2) OTTRZGU7 ACE2_HUMAN Decreases Expression [48]
Negative elongation factor A (NELFA) OT7O6E84 NELFA_HUMAN Increases Expression [139]
Rho-related GTP-binding protein RhoJ (RHOJ) OTWI65OA RHOJ_HUMAN Increases Expression [190]
Glucose-6-phosphatase 2 (G6PC2) OTET1IKU G6PC2_HUMAN Increases Expression [191]
Diablo IAP-binding mitochondrial protein (DIABLO) OTHJ9MCZ DBLOH_HUMAN Affects Localization [265]
Fibroblast growth factor 21 (FGF21) OT3RXVRD FGF21_HUMAN Increases Expression [266]
G2 and S phase-expressed protein 1 (GTSE1) OTPP742Z GTSE1_HUMAN Increases Expression [190]
FERM domain-containing protein 4A (FRMD4A) OTJDTIK2 FRM4A_HUMAN Decreases Expression [140]
Vesicular glutamate transporter 2 (SLC17A6) OTP1MJGP VGLU2_HUMAN Increases Expression [184]
ETS-related transcription factor Elf-5 (ELF5) OTLRU8YF ELF5_HUMAN Decreases Expression [140]
Endoribonuclease Dicer (DICER1) OTTVSEY0 DICER_HUMAN Increases Expression [198]
Histone deacetylase 5 (HDAC5) OTWG387P HDAC5_HUMAN Increases Expression [248]
Hepatocyte nuclear factor 3-beta (FOXA2) OTJOCVOY FOXA2_HUMAN Decreases Expression [184]
Potassium voltage-gated channel subfamily E member 2 (KCNE2) OTUO214Y KCNE2_HUMAN Affects Expression [184]
Mitogen-activated protein kinase 11 (MAPK11) OT0AS010 MK11_HUMAN Increases ADR [24]
Aromatic-L-amino-acid decarboxylase (DDC) OT0TSW09 DDC_HUMAN Increases ADR [24]
Islet amyloid polypeptide (IAPP) OT5Z8ERW IAPP_HUMAN Increases ADR [24]
Programmed cell death protein 5 (PDCD5) OT6T2DDL PDCD5_HUMAN Increases Response To Substance [267]
Cadherin-4 (CDH4) OT8LH3HN CADH4_HUMAN Increases ADR [24]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Response To Substance [268]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Response To Substance [269]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Decreases Response To Substance [270]
Gastrin (GAST) OTD0IP9N GAST_HUMAN Increases ADR [24]
Cadherin-12 (CDH12) OTF2HCGA CAD12_HUMAN Increases ADR [24]
Heat shock protein beta-1 (HSPB1) OTHFZ8ED HSPB1_HUMAN Decreases Response To Substance [265]
Poly polymerase 1 (PARP1) OTIESHK4 PARP1_ARATH Increases ADR [24]
Cadherin-11 (CDH11) OTIZKPTF CAD11_HUMAN Increases ADR [24]
Histidine decarboxylase (hdc) OTM3771T DCHS_RAOOR Increases ADR [24]
Ornithine decarboxylase (ODC1) OTNDAGRR DCOR_HUMAN Increases ADR [24]
Glutathione S-transferase Mu 1 (GSTM1) OTSBF2MO GSTM1_HUMAN Decreases Response To Substance [271]
Interferon alpha-7 (IFNA7) OTSQ6R46 IFNA7_HUMAN Increases ADR [24]
Polymerase delta-interacting protein 3 (POLDIP3) OTTB5SV7 PDIP3_HUMAN Increases Response To Substance [159]
Alpha-2-HS-glycoprotein (AHSG) OTUG0LEA FETUA_HUMAN Increases Response To Substance [159]
Progranulin (GRN) OTXXSJ53 GRN_HUMAN Decreases Response To Substance [272]
Calcitonin (CALCA) OTZ11LHB CALC_HUMAN Decreases Response To Substance [273]
Alkaline phosphatase, placental type (ALPP) OTZU4G9W PPB1_HUMAN Increases ADR [24]
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⏷ Show the Full List of 979 DOT(s)

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31 Effects of ezetimibe and/or simvastatin on LDL receptor protein expression and on LDL receptor and HMG-CoA reductase gene expression: a randomized trial in healthy men. Atherosclerosis. 2008 May;198(1):198-207.
32 In-vivo effects of simvastatin and rosuvastatin on global gene expression in peripheral blood leucocytes in a human inflammation model. Pharmacogenet Genomics. 2008 Feb;18(2):109-20.
33 Activation of nuclear factor-kappa B pathway by simvastatin and RhoA silencing increases doxorubicin cytotoxicity in human colon cancer HT29 cells. Mol Pharmacol. 2008 Aug;74(2):476-84.
34 Homocysteine modulates the effect of simvastatin on expression of ApoA-I and NF-kappaB/iNOS. Cardiovasc Res. 2008 Oct 1;80(1):151-8.
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40 Resveratrol potentiates effect of simvastatin on inhibition of mevalonate pathway in human endometrial stromal cells. J Clin Endocrinol Metab. 2013 Mar;98(3):E455-62.
41 Simvastatin protects dopaminergic neurons against MPP+-induced oxidative stress and regulates the endogenous anti-oxidant system through ERK. Cell Physiol Biochem. 2018;51(4):1957-1968.
42 Differential effects of statins on relevant functions of human monocyte-derived dendritic cells. J Leukoc Biol. 2006 Mar;79(3):529-38. doi: 10.1189/jlb.0205064. Epub 2005 Dec 30.
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73 Association of CYP1A1 and CYP1B1 inhibition in in vitro assays with drug-induced liver injury. J Toxicol Sci. 2021;46(4):167-176. doi: 10.2131/jts.46.167.
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77 Hydroxychloroquine decreases human MSC-derived osteoblast differentiation and mineralization in vitro. J Cell Mol Med. 2018 Feb;22(2):873-882. doi: 10.1111/jcmm.13373. Epub 2017 Oct 3.
78 Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients. Arterioscler Thromb Vasc Biol. 2002 Jul 1;22(7):1194-9. doi: 10.1161/01.atv.0000022694.16328.cc.
79 [Effect of simvastatin on endothelin-1 expression in endothelial cell cultured hypoxically]. Sichuan Da Xue Xue Bao Yi Xue Ban. 2008 Jan;39(1):72-5.
80 Simvastatin suppresses tissue factor expression and increases fibrinolytic activity in tumor necrosis factor-alpha-activated human peritoneal mesothelial cells. Kidney Int. 2003 Jun;63(6):2065-74. doi: 10.1046/j.1523-1755.2003.t01-2-00004.x.
81 HMG-CoA reductase inhibitor simvastatin inhibits cell cycle progression at the G1/S checkpoint in immortalized lymphocytes from Alzheimer's disease patients independently of cholesterol-lowering effects. J Pharmacol Exp Ther. 2008 Jan;324(1):352-9. doi: 10.1124/jpet.107.128959. Epub 2007 Oct 10.
82 [Simvastatin-induced apoptosis of K562 cells is mediated by endoplasmic reticulum stress]. Yao Xue Xue Bao. 2008 Apr;43(4):371-7.
83 Simvastatin induces heat shock factor 1 in vascular endothelial cells. Atherosclerosis. 2006 Oct;188(2):265-73. doi: 10.1016/j.atherosclerosis.2005.10.045. Epub 2005 Dec 20.
84 Simvastatin inhibits the proliferation of human prostate cancer PC-3 cells via down-regulation of the insulin-like growth factor 1 receptor. Biochem Biophys Res Commun. 2008 Jul 25;372(2):356-61. doi: 10.1016/j.bbrc.2008.05.043. Epub 2008 May 19.
85 Impaired migration of trophoblast cells caused by simvastatin is associated with decreased membrane IGF-I receptor, MMP2 activity and HSP27 expression. Hum Reprod. 2007 Apr;22(4):1161-7. doi: 10.1093/humrep/del464. Epub 2006 Dec 11.
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