General Information of Drug (ID: DM3KJBC)

Drug Name
Epinephrine Drug Info
Synonyms
ADROP; Adnephrine; Adrenal; Adrenalin; Adrenalina; Adrenaline; Adrenalinum; Adrenamine; Adrenan; Adrenapax; Adrenasol; Adrenatrate; Adrenine; Adrenodis; Adrenohorma; Adrenosan; Adrenutol; Adrin; Adrine; Antiasthmatique; Asthmanefrin; Astmahalin; Astminhal; Balmadren; Bernarenin; Biorenine; Bosmin; Brevirenin; Bronkaid; Chelafrin; Corisol; Drenamist; Dylephrin; Epifrin; Epiglaufrin; Epinefrin; Epinefrina; Epinephran; Epinephrin; Epinephrinum; Epipen; Epirenamine; Epirenan; Epirenin; Epitrate; Eppy; Esphygmogenina; Exadrin; Glaucon; Glaucosan; Glauposine; Glycirenan; Haemostasin; Haemostatin; Hektalin; Hemisine; Hemostasin; Hemostatin; Hypernephrin; Hyporenin; IOP; Intranefrin; Iontocaine; Isoptoepinal; Kidoline; Levoadrenaline; Levoepinephrine; Levorenen; Levorenin; Levorenine; Lyophrin; Metanephrin; Methylaminoethanolcatechol; Methylarterenol; Micronefrin; Micronephrine; Mucidrina; Myosthenine; Mytrate; Nephridine; Nieraline; Paranephrin; Primatene; Racepinephrine; Renagladin; Renaglandin; Renaglandulin; Renaleptine; Renalina; Renoform; Renostypricin; Renostypticin; Renostyptin; Scurenaline; Septocaine; Simplene; Sindrenina; Soladren; Sphygmogenin; Stryptirenal; Styptirenal; Supracapsulin; Supradin; Supranefran; Supranephrane; Supranephrine; Supranol; Suprarenaline; Suprarenin; Suprel; Surenine; Surrenine; Susphrine; Takamina; Takamine; Tokamina; Tonogen; Twinject; Vaponefrin; Vasoconstrictine; Vasoconstrictor; Vasodrine; Vasoton; Vasotonin; ADR ADRENALINE; Adrenalin in Oil; Adrenalina [DCIT]; Asmatane Mist; Asthma meter mist; Asthmahaler Mist; Bronkaid Mist; Bronkaid Suspension Mist; Bupivacaine Hcl and Epinephrine; Citanest Forte; EPI E Z PEN JR; EPIPEN E Z PEN; EPIPEN JR; Epi EZ Pen Jr; Epinefrin [Czech]; Epinephrine hydrochloride; Epipen EZ Pen; Primatene Mist; Racemic Epinephrine; Sympathin I; Adrenalin (TN); Adrenalin-Medihaler; Adrenaline (JP15); Adrenaline/Epinephrine; Ana-Guard; Asthma-nefrin; D-Adrenaline; D-Epifrin; D-Epinephrine; Dyspne-Inhal; Epinefrina [INN-Spanish]; Epinephrine (USP); Epinephrinum [INN-Latin]; Epipen (TN); Epipen Auto-Injector; Epipen Jr.; L-Adrenalin; L-Adrenaline; L-Adrenaline Base; L-Epinehphrine; L-Epinephine; L-Epirenamine; L-Methylaminoethanolcatechol; L-epinephrine; Levo-Methylaminoethanolcatechol; Medihaler-Epi; R-Adrenaline; Sus-Phrine; Twinject 0.15; Twinject 0.3; Twinject 0.30; Epinephrine (USP/INN); Epinephrine [USAN:INN:JAN]; Epipen Jr. Auto-Injector; L-Epinephrine (synthetic); SUS-PHRINE SULFITE-FREE; R-(-)-Epinephrine; L-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol; (-)-(R)-Epinephrine; (-)-3,4-Dihydroxy-alpha-((methylamino)methyl)benzyl alcohol; (-)-Adrenalin; (-)-Adrenaline; (-)-R-Epinephrine; (R)-(-)-Adnephrine; (R)-(-)-Adrenaline; (R)-(-)-Epinephrine; (R)-(-)-Epirenamine; (R)-4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; (R)-Adrenaline; (R)-Epinephrine; 1-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol; 1-Adrenalin; 1-Epinephrine; 4-(1-Hydroxy-2-(methylamino)ethyl)-1,2-benzenediol; 4-(1-hydroxy-2-methylamino-ethyl)benzene-1,2-diol; 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
Indication
Disease Entry ICD 11 Status REF
Allergy 4A80-4A85 Approved [1] , [2] , [3]
Therapeutic Class
Vasoconstrictor Agents
Cross-matching ID
PubChem CID
5816
ChEBI ID
CHEBI:28918
CAS Number
CAS 51-43-4
TTD Drug ID
DM3KJBC
VARIDT Drug ID
DR00076
INTEDE Drug ID
DR0590
ACDINA Drug ID
D00234

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
Drug Status:
Approved Drug(s)
Investigative Drug(s)
Discontinued Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [12]
Estradiol DMUNTE3 Breast cancer 2C60-2C65 Approved [13]
Acetaminophen DMUIE76 Pain MG30-MG3Z Approved [14]
Etoposide DMNH3PG Solid tumour/cancer 2A00-2F9Z Approved [15]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [17]
Mycophenolate mofetil DMPQAGE Organ transplant rejection NE84 Approved [18]
Metronidazole DMTIVEN Amoebiasis 1A36 Approved [19]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [20]
Ethanol DMDRQZU Chronic pain MG30 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Sulfotransferase 1A1 (SULT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Premature labour JB00 Approved [22]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [23]
Estradiol DMUNTE3 Breast cancer 2C60-2C65 Approved [24]
Acetaminophen DMUIE76 Pain MG30-MG3Z Approved [25]
Aspirin DM672AH Myocardial infarction BA41-BA43 Approved [26]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [27]
Cholic acid DM7OKQV Peroxisomal disorder 5C57 Approved [28]
Liothyronine DM6IR3P Hypothyroidism 5A00 Approved [29]
Benzyl alcohol DMBVYDI Head and body lice 1G00.0 Approved [30]
Teicoplanin DMAQ2LK Bacterial infection 1A00-1C4Z Approved [31]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Thiopurine methyltransferase (TPMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL leukaemia 2A60-2B33 Approved [32]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [33]
Estradiol DMUNTE3 Breast cancer 2C60-2C65 Approved [34]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [35]
Ergotidine DM78IME Respiratory allergy 4A80 Approved [36]
Vitamin C DMXJ7O8 Vitamin C deficiency 5B56 Approved [37]
Cefazolin DMPDYFR Bacterial infection 1A00-1C4Z Approved [38]
Levodopa DMN3E57 Parkinson disease 8A00.0 Approved [39]
Thioguanine DM7NKEV Acute myeloid leukaemia 2A60 Approved [40]
Azathioprine DMMZSXQ Organ transplant rejection NE84 Approved [41]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Catechol O-methyltransferase (COMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dopamine DMPGUCF Parkinson disease 8A00.0 Approved [42]
Dobutamine DMD1B8Z Heart failure BD10-BD13 Approved [43]
Methylenedioxymethamphetamine DMYVU47 Discovery agent N.A. Investigative [44]
Drug(s) Metabolized By Monoamine oxidase type A (MAO-A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [45]
Naratriptan DMO50U2 Migraine 8A80 Approved [46]
Safinamide mesylate DM0J2ZT Parkinson disease 8A00.0 Approved [47]
Almotriptan malate DMFG5ST Migraine 8A80 Approved [48]
Serotonin DMOFCRY Discovery agent N.A. Investigative [49]
Phenethylamine DMX0G4F Discovery agent N.A. Investigative [49]
Benzylamine DMRM6ES Chronic functional vomiting DD90.4 Investigative [49]
⏷ Show the Full List of 7 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Migraine 8A80 Approved [50]
Ergotidine DM78IME Respiratory allergy 4A80 Approved [5]
Metformin DM89QE1 Type-2 diabetes 5A11 Approved [51]
Clonidine DM6RZ9Q Hypertension BA00-BA04 Approved [50]
Entecavir DM7VTQO Hepatitis B virus infection 1E51.0 Approved [52]
Norepinephrine DMOUC09 Sepsis 1G40-1G41 Approved [5]
Amphetamine DMSZQAK Attention deficit hyperactivity disorder 6A05.Z Approved [53]
Acetylcholine DMDF79Z Cataract 9B10 Approved [54]
Sodium chloride DMM3950 Skin burns ME65.0 Approved [55]
Etilefrine DM67PWD Cardiovascular disease BA00-BE2Z Withdrawn from market [56]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [57]
Cisplatin DMRHGI9 Solid tumour/cancer 2A00-2F9Z Approved [58]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [59]
Oxaliplatin DMQNWRD Colorectal cancer 2B91.Z Approved [60]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [6]
Verapamil DMA7PEW Hypertension BA00-BA04 Approved [61]
Sorafenib DMS8IFC Hepatocellular carcinoma 2C12.02 Approved [62]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [63]
Dopamine DMPGUCF Parkinson disease 8A00.0 Approved [64]
Propranolol DM79NTF Migraine 8A80 Approved [50]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Propranolol DM79NTF Migraine 8A80 Approved [65]
Norepinephrine DMOUC09 Sepsis 1G40-1G41 Approved [66]
Atenolol DMNKG1Z Hypertension BA00-BA04 Approved [67]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [67]
Metoprolol DMOJ0V6 Hypertension BA00-BA04 Approved [67]
Timolol DM3NXRU High blood pressure BA00 Approved [68]
Isoproterenol DMK7MEY Heart block BC63 Approved [69]
Betaxolol DM6EUL5 Hypertension BA00-BA04 Approved [70]
Sotalol DML60TN Sinus rhythm disorder BC9Y Approved [71]
Nadolol DMW6GVL High blood pressure BA00 Approved [72]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Adrenergic receptor beta-1 (ADRB1) TTR6W5O ADRB1_HUMAN Agonist [4]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Organic cation transporter 3 (SLC22A3) DT6201N S22A3_HUMAN Substrate [5]
Organic cation transporter 1 (SLC22A1) DTT79CX S22A1_HUMAN Substrate [6]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Substrate [7]
Sulfotransferase 1A1 (SULT1A1) DEYWLRK ST1A1_HUMAN Substrate [8]
Monoamine oxidase type A (MAO-A) DERE4TU AOFA_HUMAN Substrate [9]
Catechol O-methyltransferase (COMT) DEV3T4A COMT_HUMAN Substrate [10]
Thiopurine methyltransferase (TPMT) DEFQ8VO TPMT_HUMAN Substrate [11]

References

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