Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMYRX8B)

Drug Name
Ardeparin Drug Info
Synonyms
Arteven; Bemiparin; Certoparin; Clivarine; Dalteparin; Eparina; Fluxum; Fraxiparin; Heparina; Heparinate; Heparine; Heparinum; Hepathrom; Innohep; Liquaemin; Liquemin; Logiparin; Multiparin; Nadroparin; Nadroparine; Novoheparin; Pabyrin; Parnaparin; Parvoparin; Pularin; Sandoparin; Subeparin; Sublingula; Thromboliquine; Tinzaparin; Triofiban; Vetren; Allocinnamic acid; Ardeparin sodium; Bemiparin sodium; Enoxaparin sodium; Eparina [DCIT]; Fragmin A; Fragmin B; Fragmin IV; Hep Flush Kit in plastic container; Heparin Lock Flush in plastic container; Heparin Lock Flush preservative free; Heparin Lock Flush preservative free in plastic container; Heparin natrium; Heparin sulfate; Heparinic acid; Heparinum natricum; Isocinnamic acid; Minolteparin sodium; Parnaparin sodium; Reviparin sodium; Sodium acid heparin; Sodium heparinate; Tinzaparin sodium; Vitrum AB; CY 216; Cy 222; FR 860; H 2149; Heparin CY 216; KB 101; Kabi 2165; LHN 1; Lioton 1000; OP 386; OP 622; Ro 11; WY 90493RD; ALFA 87-120; ALFA 87-163; ALFA 87-198; ALFA 87-81; ALFA 88-247; Alpha-Heparin; Cis-Cinnamic acid; Depo-Heparin; Hed-heparin; Hep-Lock; Heparin, sodium salt; Heparina [INN-Spanish]; Heparine [INN-French]; Heparinum [INN-Latin]; Hepflush-10; Inno-Hep; Normiflo (TN); Hep-Lock U/P; Cis-.beta.-Carboxystyrene
Indication
Disease Entry ICD 11 Status REF
Deep vein thrombosis BD71 Approved [1]
Venous thrombosis BA43 Approved [2]
Thrombosis DB61-GB90 Phase 3 [3]
Venous thromboembolism BD72 Phase 3 [4]
Therapeutic Class
Anticoagulants
Cross-matching ID
PubChem CID
772
CAS Number
CAS 9005-49-6
TTD Drug ID
DMYRX8B

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Investigative Drug(s)
Preclinical Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Antithrombin-III (ATIII)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Heparin Calcium DMEVXY6 Coagulation defect 3B10.0 Approved [5]
Sulodexide DMNUC42 Tinnitus MC41 Approved [14]
Heparin Sodium DM9KHZL Coagulation defect 3B10.0 Approved [15]
Unfractionated heparin DMCWM03 Thrombosis DB61-GB90 Phase 3 [16]
Heparin low molecular weight DMGFULM Thrombosis DB61-GB90 Phase 3 [17]
KW-3357 DMP3GI2 Coagulation defect 3B10.0 Phase 3 [18]
O-desulfated heparin DMJL4A7 Chronic obstructive pulmonary disease CA22 Phase 2 [19]
M118 DML0I2Z Acute coronary syndrome BA41 Phase 2 [20]
PMX-60056 DMWT73D Coagulation defect 3B10.0 Phase 2 [21]
MER-102 DME18UM Thrombosis DB61-GB90 Phase 1 [22]
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Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [24]
Haloperidol DM96SE0 Delirium Approved [25]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [26]
Selenium DM25CGV N. A. N. A. Approved [27]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [28]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [29]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [31]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
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Drug(s) Affected By Fibroblast growth factor 19 (FGF19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clavulanate DM2FGRT Bacteremia 1A73 Approved [33]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [34]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [36]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [38]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [34]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [34]
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Drug(s) Affected By Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [40]
Gefitinib DM15F0X Colon adenocarcinoma Approved [41]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [42]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [43]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [44]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [45]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Selenium DM25CGV N. A. N. A. Approved [48]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [49]
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Drug(s) Affected By Prothrombin (F2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [50]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [51]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [53]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [54]
Phytonadione DM8HDOL Bleeding disorder GA20-GA21 Approved [55]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Testosterone enanthate DMB6871 N. A. N. A. Approved [57]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [58]
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Drug(s) Affected By Coagulation factor X (F10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [59]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [60]
Estriol DMOEM2I Hormone deficiency 5A61.1 Approved [61]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [63]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [64]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [65]
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Drug(s) Affected By Urokinase-type plasminogen activator (PLAU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [66]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Quercetin DM3NC4M Obesity 5B81 Approved [68]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [69]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [70]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [66]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [71]
Leflunomide DMR8ONJ Arthritis FA20 Approved [72]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [73]
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Drug(s) Affected By Antithrombin-III (SERPINC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [74]
Prednisone DM2HG4X Acute asthma CA23 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Testosterone enanthate DMB6871 N. A. N. A. Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Aminocaproic Acid DMFGND4 Bleeding disorder GA20-GA21 Approved [75]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [78]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [79]
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Drug(s) Affected By Complement C3 (C3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [80]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [81]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [82]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [59]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [85]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [86]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [82]
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Drug(s) Affected By Complement C5 (C5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [87]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
Olanzapine DMPFN6Y Bipolar depression Approved [90]
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Drug(s) Affected By Protein c-Fos (FOS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [91]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [92]
Verapamil DMA7PEW Angina pectoris BA40 Approved [93]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Acebutolol DM0TI4U Hypertension BA00-BA04 Approved [93]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [94]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Methotrexate DM2TEOL Anterior urethra cancer Approved [96]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [97]
Quercetin DM3NC4M Obesity 5B81 Approved [98]
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Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [99]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [94]
Gefitinib DM15F0X Colon adenocarcinoma Approved [100]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [101]
Selenium DM25CGV N. A. N. A. Approved [102]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [103]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [104]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [105]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
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Drug(s) Affected By Pro-epidermal growth factor (EGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [106]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [107]
Quercetin DM3NC4M Obesity 5B81 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [108]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [109]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [110]
Testosterone DM7HUNW Hot flushes GA30 Approved [111]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
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Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [113]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [114]
Fructose DM43AN2 Vomiting MD90 Approved [25]
Ketoprofen DMRKXPT Bursitis Approved [25]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [115]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [117]
Gefitinib DM15F0X Colon adenocarcinoma Approved [118]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [119]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
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Drug(s) Affected By Fibrinogen alpha chain (FGA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [121]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Folic Acid DMEMBJC Colorectal carcinoma Approved [122]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [123]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [124]
Arsenic DMTL2Y1 N. A. N. A. Approved [125]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [126]
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Drug(s) Affected By C-reactive protein (CRP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [25]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [127]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [129]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [35]
Acalabrutinib DM7GCVW leukaemia 2A60-2B33 Approved [130]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [131]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [132]
Tibolone DM78XFG Anabolic metabolism 5C50-5C8Z Approved [133]
Testosterone DM7HUNW Hot flushes GA30 Approved [111]
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Drug(s) Affected By Serum amyloid P-component (APCS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [59]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valsartan DMREUQ6 Chronic heart failure BD1Z Approved [134]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [135]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [136]
Arsenic DMTL2Y1 N. A. N. A. Approved [125]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [63]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [56]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [137]
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Drug(s) Affected By Platelet basic protein (PPBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [138]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [140]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [140]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [141]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [142]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [144]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [145]
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Drug(s) Affected By Platelet factor 4 (PF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [138]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [146]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Fructose DM43AN2 Vomiting MD90 Approved [147]
Nortriptyline DM4KDYJ Depression 6A70-6A7Z Approved [140]
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [148]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [145]
Arsenic DMTL2Y1 N. A. N. A. Approved [149]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [150]
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Drug(s) Affected By Transferrin receptor protein 1 (TFRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [152]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [153]
Quercetin DM3NC4M Obesity 5B81 Approved [154]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [155]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [156]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [157]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [158]
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Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [159]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [160]
Etretinate DM2CZFA Keratosis ED56 Approved [161]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [163]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [164]
Quercetin DM3NC4M Obesity 5B81 Approved [165]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [166]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
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Drug(s) Affected By Vitamin K-dependent protein C (PROC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Desogestrel DM27U4Y Contraception QA21 Approved [168]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Testosterone DM7HUNW Hot flushes GA30 Approved [111]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [169]
Testosterone enanthate DMB6871 N. A. N. A. Approved [57]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Clozapine DMFC71L Schizophrenia 6A20 Approved [170]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [59]
Clomipramine DMINRKW Depression 6A70-6A7Z Approved [171]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [173]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [175]
Paclitaxel DMLB81S Breast carcinoma Approved [176]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [177]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [178]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [179]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [180]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [181]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [182]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [184]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [185]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [186]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [187]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [188]
Methotrexate DM2TEOL Anterior urethra cancer Approved [181]
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Drug(s) Affected By Endothelin-1 (EDN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [191]
Methotrexate DM2TEOL Anterior urethra cancer Approved [163]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [192]
Quercetin DM3NC4M Obesity 5B81 Approved [193]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [194]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [195]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [196]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [197]
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Drug(s) Affected By Keratin, type I cytoskeletal 18 (KRT18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [198]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [199]
Selenium DM25CGV N. A. N. A. Approved [200]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [201]
Methotrexate DM2TEOL Anterior urethra cancer Approved [202]
Quercetin DM3NC4M Obesity 5B81 Approved [203]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [110]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [204]
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Drug(s) Affected By 72 kDa type IV collagenase (MMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [160]
Selenium DM25CGV N. A. N. A. Approved [48]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [205]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [207]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [71]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [209]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [210]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 2 (FGF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [211]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [92]
Diazepam DM08E9O Alcohol withdrawal Approved [212]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [213]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [214]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [215]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [216]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [217]
Isradipine DMA5XGH Hypertension BA00-BA04 Approved [218]
Valdecoxib DMAY7H4 Osteoarthritis FA00-FA05 Approved [219]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [220]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [221]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [222]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [184]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [223]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [186]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [224]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [225]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [224]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [226]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [227]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [228]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [229]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [25]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Verapamil DMA7PEW Angina pectoris BA40 Approved [230]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [231]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin alpha-M (ITGAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [233]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [194]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [234]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [235]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [236]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [237]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [238]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [239]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [240]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [241]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor receptor 1 (FGFR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [194]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [242]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [242]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [204]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 5 (FGF5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [243]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [244]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [245]
Arsenic DMTL2Y1 N. A. N. A. Approved [246]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [247]
Paclitaxel DMLB81S Breast carcinoma Approved [248]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [248]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [249]
Suramin DMTOUY9 African trypanosomiasis 1F51 Phase 1 [250]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [137]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By L-selectin (SELL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [251]
Meloxicam DM2AR7L Arthritis FA20 Approved [251]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [194]
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [252]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [251]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [253]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [251]
Phenylbutazone DMAYL0T Chronic pain MG30 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepatocyte growth factor (HGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Quercetin DM3NC4M Obesity 5B81 Approved [254]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [255]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [255]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [256]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [257]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [258]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [259]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrix metalloproteinase-9 (MMP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [260]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [80]
Gefitinib DM15F0X Colon adenocarcinoma Approved [118]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Selenium DM25CGV N. A. N. A. Approved [48]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [261]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [262]
Methotrexate DM2TEOL Anterior urethra cancer Approved [263]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [264]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By P-selectin (SELP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [267]
Amlodipine DMBDAZV Angina pectoris BA40 Approved [143]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [268]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [269]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [270]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Platelet-derived growth factor receptor alpha (PDGFRA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [216]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Vismodegib DM5IXKQ Basal cell carcinoma 2C32 Approved [271]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [272]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [273]
Folic Acid DMEMBJC Colorectal carcinoma Approved [274]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [144]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [275]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Complement receptor type 1 (CR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [276]
Methotrexate DM2TEOL Anterior urethra cancer Approved [67]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [277]
Josamycin DMKJ8LB Bacterial infection 1A00-1C4Z Approved [278]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [279]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [280]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [137]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [199]
Maleic Acid DM4L0R7 Discovery agent N.A. Investigative [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Syndecan-1 (SDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [282]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [70]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [141]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [204]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [144]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [283]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin alpha-X (ITGAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [284]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [157]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [285]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [204]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [237]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [286]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [287]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [288]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [288]
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [289]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bone morphogenetic protein 6 (BMP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [224]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [224]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [290]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [224]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [224]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [224]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [224]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [291]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [224]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [292]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor receptor 4 (FGFR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [293]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [35]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Testosterone DM7HUNW Hot flushes GA30 Approved [111]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [144]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [60]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor receptor superfamily member 6 (FAS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [198]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [295]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [296]
Methotrexate DM2TEOL Anterior urethra cancer Approved [297]
Epinephrine DM3KJBC Acute asthma CA23 Approved [298]
Quercetin DM3NC4M Obesity 5B81 Approved [299]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [300]
Fructose DM43AN2 Vomiting MD90 Approved [147]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [301]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [302]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [303]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [304]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [305]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [306]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [307]
Gefitinib DM15F0X Colon adenocarcinoma Approved [308]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [309]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [310]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-6 (PSMB6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [311]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [312]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [124]
Arsenic DMTL2Y1 N. A. N. A. Approved [125]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [150]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [313]
Paclitaxel DMLB81S Breast carcinoma Approved [248]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-5 (PSMB5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Sibutramine DMFJTDI Obesity 5B81 Approved [314]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [150]
Bortezomib DMNO38U Leukemia Approved [315]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [316]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [200]
WP-1066 DMUGHWR Recurrent glioblastoma 2A00.00 Phase 1/2 [316]
MG-132 DMKA2YS N. A. N. A. Preclinical [317]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [318]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [319]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [303]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [320]
Paclitaxel DMLB81S Breast carcinoma Approved [321]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [322]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [302]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [25]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [323]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [116]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [305]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CD40 ligand (CD40LG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [120]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [324]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [267]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [325]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [268]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [326]
Menthol DMG2KW7 Back pain ME84.Z Approved [327]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [328]
Eptifibatide DMQXTJS Acute cardiac ischemic events BA40.Z Approved [329]
Candesartan DMRK8OT Chronic heart failure BD1Z Approved [326]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Syndecan-4 (SDC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [330]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [52]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [101]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [331]
Leflunomide DMR8ONJ Arthritis FA20 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [332]
Epanova DMHEAGL Hypertriglyceridemia 5C80.1 Approved [333]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [334]
Folic Acid DMEMBJC Colorectal carcinoma Approved [335]
Methotrexate DM2TEOL Anterior urethra cancer Approved [336]
Quercetin DM3NC4M Obesity 5B81 Approved [337]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [338]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [339]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [340]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [341]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [342]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [342]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Syndecan-2 (SDC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [70]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [311]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [144]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [243]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [89]
Paclitaxel DMLB81S Breast carcinoma Approved [343]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bone morphogenetic protein receptor type-1A (BMPR1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [273]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [144]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [344]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
Arsenic DMTL2Y1 N. A. N. A. Approved [125]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [345]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [346]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [347]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [348]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [350]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [175]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [351]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [352]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [353]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [354]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [355]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [356]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [357]
Gefitinib DM15F0X Colon adenocarcinoma Approved [41]
Prednisone DM2HG4X Acute asthma CA23 Approved [358]
Methotrexate DM2TEOL Anterior urethra cancer Approved [359]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [360]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [43]
Quercetin DM3NC4M Obesity 5B81 Approved [361]
Fluoxetine DM3PD2C Bipolar depression Approved [362]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [363]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [364]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromal cell-derived factor 1 (CXCL12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [198]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [365]
Methotrexate DM2TEOL Anterior urethra cancer Approved [30]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [366]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [84]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Estrone DM5T6US Acne vulgaris ED80 Approved [365]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [367]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [368]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrix metalloproteinase-14 (MMP14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [48]
Panobinostat DM58WKG Chronic graft versus host disease Approved [37]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Clozapine DMFC71L Schizophrenia 6A20 Approved [369]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [370]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [371]
Cysteamine DMSYFM8 Nephropathic cystinosis 5C60 Approved [372]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-X-C chemokine receptor type 4 (CXCR4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [198]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [373]
Methotrexate DM2TEOL Anterior urethra cancer Approved [181]
Quercetin DM3NC4M Obesity 5B81 Approved [299]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [374]
Carfilzomib DM48K0X Multiple myeloma 2A83 Approved [375]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [70]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [376]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [377]
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Drug(s) Affected By Hepcidin (HAMP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [378]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [188]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [379]
Leflunomide DMR8ONJ Arthritis FA20 Approved [72]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [9]
Papaverine DMCA9QP Brain ischaemia 8B1Z Approved [9]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [76]
Ethanol DMDRQZU Chronic pain MG30 Approved [380]
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Drug(s) Affected By Transcription factor E2F1 (E2F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [381]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [382]
Gefitinib DM15F0X Colon adenocarcinoma Approved [383]
Selenium DM25CGV N. A. N. A. Approved [200]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [282]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [384]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [385]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [69]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [226]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [356]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [183]
Verapamil DMA7PEW Angina pectoris BA40 Approved [230]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [198]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [386]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [387]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [95]
Meloxicam DM2AR7L Arthritis FA20 Approved [388]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [389]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [390]
Verapamil DMA7PEW Angina pectoris BA40 Approved [391]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [23]
Selenium DM25CGV N. A. N. A. Approved [200]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [392]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [393]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [394]
Quercetin DM3NC4M Obesity 5B81 Approved [32]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [395]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-7 (PSMB7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [273]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Benzatropine DMF7EXL Parkinsonian disorder Approved [396]
Clozapine DMFC71L Schizophrenia 6A20 Approved [396]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [397]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [150]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [398]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [346]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-acetylglucosamine-6-sulfatase (GNS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [200]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [56]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [273]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [399]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [400]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [39]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [401]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [402]
PP-242 DM2348V Discovery agent N.A. Investigative [403]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Macrophage migration inhibitory factor (MIF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [404]
Quercetin DM3NC4M Obesity 5B81 Approved [405]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [406]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [407]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [39]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [77]
Folic Acid DMEMBJC Colorectal carcinoma Approved [408]
Benzatropine DMF7EXL Parkinsonian disorder Approved [396]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [89]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [62]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Antithrombin-III (ATIII) TT4QPUL ANT3_HUMAN Modulator [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [6]
Antithrombin-III (SERPINC1) OTDFATG0 ANT3_HUMAN Gene/Protein Processing [7]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [8]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [8]
Bone morphogenetic protein 6 (BMP6) OT9WN536 BMP6_HUMAN Gene/Protein Processing [9]
Bone morphogenetic protein receptor type-1A (BMPR1A) OTQOA4ZH BMR1A_HUMAN Gene/Protein Processing [9]
C-reactive protein (CRP) OT0RFT8F CRP_HUMAN Gene/Protein Processing [10]
C-X-C chemokine receptor type 4 (CXCR4) OTUFSBX2 CXCR4_HUMAN Gene/Protein Processing [11]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Gene/Protein Processing [12]
Catalase (CAT) OTHEBX9R CATA_HUMAN Gene/Protein Processing [13]

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