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Gemcitabine FDA Label
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Omeprazole inhibits pancreatic cancer cell invasion through a nongenomic aryl hydrocarbon receptor pathway. Chem Res Toxicol. 2015 May 18;28(5):907-18.
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Inhibition of DCLK1 down-regulates PD-L1 expression through Hippo pathway in human pancreatic cancer.Life Sci. 2020 Jan 15;241:117150. doi: 10.1016/j.lfs.2019.117150. Epub 2019 Dec 11.
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Fn3 proteins engineered to recognize tumor biomarker mesothelin internalize upon binding.PLoS One. 2018 May 8;13(5):e0197029. doi: 10.1371/journal.pone.0197029. eCollection 2018.
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Ultrasensitive MRI detection of spontaneous pancreatic tumors with nanocage-based targeted contrast agent.Biomaterials. 2018 Jan;152:37-46. doi: 10.1016/j.biomaterials.2017.10.029. Epub 2017 Oct 20.
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Urokinase-type plasminogen activator receptor transcriptionally controlled adenoviruses eradicate pancreatic tumors and liver metastasis in mouse models.Neoplasia. 2009 Jun;11(6):518-28, 4 p following 528. doi: 10.1593/neo.81674.
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Cyclooxygenase-2 Influences Response to Cotargeting of MEK and CDK4/6 in a Subpopulation of Pancreatic Cancers.Mol Cancer Ther. 2018 Dec;17(12):2495-2506. doi: 10.1158/1535-7163.MCT-18-0082. Epub 2018 Sep 25.
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Rare ALK expression but no ALK rearrangement in pancreatic ductal adenocarcinoma and neuroendocrine tumors.Pancreas. 2013 Aug;42(6):949-51. doi: 10.1097/MPA.0b013e3182847bd0.
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Hypoxia-dependent expression of ADAM8 in human pancreatic cancer cell lines.Exp Oncol. 2008 Jun;30(2):129-32.
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New Blocking Antibodies against Novel AGR2-C4.4A Pathway Reduce Growth and Metastasis of Pancreatic Tumors and Increase Survival in Mice.Mol Cancer Ther. 2015 Apr;14(4):941-51. doi: 10.1158/1535-7163.MCT-14-0470. Epub 2015 Feb 2.
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Inhibition of AKT2 enhances sensitivity to gemcitabine via regulating PUMA and NF-B signaling pathway in human pancreatic ductal adenocarcinoma.Int J Mol Sci. 2012;13(1):1186-1208. doi: 10.3390/ijms13011186. Epub 2012 Jan 20.
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Annexin A10 is a candidate marker associated with the progression of pancreatic precursor lesions to adenocarcinoma.PLoS One. 2017 Apr 3;12(4):e0175039. doi: 10.1371/journal.pone.0175039. eCollection 2017.
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Inhibition of ATM Increases Interferon Signaling and Sensitizes Pancreatic Cancer to Immune Checkpoint Blockade Therapy.Cancer Res. 2019 Aug 1;79(15):3940-3951. doi: 10.1158/0008-5472.CAN-19-0761. Epub 2019 May 17.
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Warfarin Blocks Gas6-Mediated Axl Activation Required for Pancreatic Cancer Epithelial Plasticity and Metastasis. Cancer Res. 2015 Sep 15;75(18):3699-705. doi: 10.1158/0008-5472.CAN-14-2887-T. Epub 2015 Jul 23.
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Histone deacetylase inhibitor trichostatin A and proteasome inhibitor PS-341 synergistically induce apoptosis in pancreatic cancer cells.Biochem Biophys Res Commun. 2006 Oct 6;348(4):1245-53. doi: 10.1016/j.bbrc.2006.07.185. Epub 2006 Aug 7.
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A double missense variation of the BUB1 gene and a defective mitotic spindle checkpoint in the pancreatic cancer cell line Hs766T.Hum Mutat. 2003 Apr;21(4):445. doi: 10.1002/humu.9120.
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Pancreatic carcinoma cells colonizing the liver modulate the expression of their extracellular matrix genes.Genes Cancer. 2018 May;9(5-6):215-231. doi: 10.18632/genesandcancer.179.
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Therapeutic anti-CD147 antibody sensitizes cells to chemoradiotherapy via targeting pancreatic cancer stem cells.Am J Transl Res. 2019 Jun 15;11(6):3543-3554. eCollection 2019.
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Enzyme-Driven Chemo-and Radiation-Therapy with 12 Pyrimidine Nucleoside Analogs Not Yet in the Clinic.Anticancer Agents Med Chem. 2017;17(2):250-264. doi: 10.2174/1871520616666161013145853.
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A Novel CDC25B Promoter-Based Oncolytic Adenovirus Inhibited Growth of Orthotopic Human Pancreatic Tumors in Different Preclinical Models.Clin Cancer Res. 2015 Apr 1;21(7):1665-74. doi: 10.1158/1078-0432.CCR-14-2316. Epub 2015 Jan 8.
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Expression and Role of MicroRNAs from the miR-200 Family in the Tumor Formation and Metastatic Propensity of Pancreatic Cancer.Mol Ther Nucleic Acids. 2019 Sep 6;17:491-503. doi: 10.1016/j.omtn.2019.06.015. Epub 2019 Jun 29.
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Immunohistochemical investigation of F344/N rat islet cell tumors from national toxicology program studies.Toxicol Pathol. 2012 Jul;40(5):751-63. doi: 10.1177/0192623312441407. Epub 2012 Apr 3.
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Identification of c-FLIP(L) and c-FLIP(S) as critical regulators of death receptor-induced apoptosis in pancreatic cancer cells.Gut. 2011 Feb;60(2):225-37. doi: 10.1136/gut.2009.202325. Epub 2010 Sep 28.
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Low frequency of CHEK2 mutations in familial pancreatic cancer.Fam Cancer. 2006;5(4):305-8. doi: 10.1007/s10689-006-7850-4. Epub 2006 Jul 20.
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Inhibition of Cell Proliferation and Growth of Pancreatic Cancer by Silencing of Carbohydrate Sulfotransferase 15 In Vitro and in a Xenograft Model. PLoS One. 2015 Dec 7;10(12):e0142981.
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Cannabinoids induce apoptosis of pancreatic tumor cells via endoplasmic reticulum stress-related genes. Cancer Res. 2006 Jul 1;66(13):6748-55. doi: 10.1158/0008-5472.CAN-06-0169.
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Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines.FEBS Lett. 2006 Oct 30;580(25):5836-44. doi: 10.1016/j.febslet.2006.09.042. Epub 2006 Sep 27.
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Enhanced citrate synthase activity in human pancreatic cancer.Pancreas. 2005 Mar;30(2):99-104. doi: 10.1097/01.mpa.0000153326.69816.7d.
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Chondroitin sulfate proteoglycan CSPG4 as a novel hypoxia-sensitive marker in pancreatic tumors.PLoS One. 2014 Jun 16;9(6):e100178. doi: 10.1371/journal.pone.0100178. eCollection 2014.
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Emodin sensitizes human pancreatic cancer cells to EGFR inhibitor through suppressing Stat3 signaling pathway.Cancer Manag Res. 2019 Sep 17;11:8463-8473. doi: 10.2147/CMAR.S221877. eCollection 2019.
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A small interfering RNA targeting proteinase-activated receptor-2 is effective in suppression of tumor growth in a Panc1 xenograft model.Int J Cancer. 2008 Feb 1;122(3):658-63. doi: 10.1002/ijc.23123.
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Chemoprevention of pancreatic cancer: characterization of Par-4 and its modulation by 3,3' diindolylmethane (DIM).Pharm Res. 2008 Sep;25(9):2117-24. doi: 10.1007/s11095-008-9581-8. Epub 2008 Apr 22.
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A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer.Nat Genet. 2015 Jan;47(1):47-56. doi: 10.1038/ng.3164. Epub 2014 Dec 8.
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Growth of human pancreatic cancer is inhibited by down-regulation of gastrin gene expression.Pancreas. 2009 Jul;38(5):e151-61. doi: 10.1097/MPA.0b013e3181a66fdc.
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Geminin is overexpressed in human pancreatic cancer and downregulated by the bioflavanoid apigenin in pancreatic cancer cell lines.Mol Carcinog. 2008 Nov;47(11):835-44. doi: 10.1002/mc.20441.
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Autocrine motility factor signaling enhances pancreatic cancer metastasis.Clin Cancer Res. 2004 Nov 15;10(22):7775-84. doi: 10.1158/1078-0432.CCR-04-1015.
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Induction of hepatocyte growth factor activator gene expression under hypoxia activates the hepatocyte growth factor/c-Met system via hypoxia inducible factor-1 in pancreatic cancer.Cancer Sci. 2008 Jul;99(7):1341-7. doi: 10.1111/j.1349-7006.2008.00828.x. Epub 2008 Apr 16.
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Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1 Inhibitor Impairs Pancreatic Tumor Growth.ACS Nano. 2019 Feb 26;13(2):2176-2189. doi: 10.1021/acsnano.8b08823. Epub 2019 Jan 28.
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