Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMBXVMZ)

• Drug Name: Dihydroartemisinin Drug Info
• Synonyms: Artenimol; Cotecxin; Dihydroartemisinine; Dihydroqinghaosu; Dihydroquinghaosu; Dihydroquinghoasu; VM3352; Artenimol (INN); JAV-110; GNF-PF-5634; (3R,5aS,6R,8aS,9R,12R,12aR)-3,6,9-trimethyldecahydro-3,12-epoxypyrano[4,3-j][1,2]benzodioxepin-10-ol; [3R-(3.alpha.,5a.beta.,6.beta.,8a.beta.,9.alpha.,10.alpha.,12.beta.,12aR*)]-Decahydro-10-hydroxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4.3-j]-1,2-benzodioxepin; 1,5,9-trimethyl-(1R,4S,5R,8S,9R,10S,12R,13R)-11,14,15,16-tetraoxatetracyclo[10.3.1.04,13.08,13]hexadecan-10-ol(Dihydroartemisinin)

Indication

Disease Entry	ICD 11	Status	REF
Malaria	1F40-1F45	Approved	[1]

• Cross-matching ID:
  PubChem CID: 3000518
  ChEBI ID: CHEBI:135921
  CAS Number: CAS 71939-50-9
  TTD Drug ID: DMBXVMZ
  INTEDE Drug ID: DR0142

Molecule-Related Drug Atlas

Drug(s) Targeting Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Artemisinin	DMOY7W3	Malaria	1F40-1F45	Approved	[1]
Piperaquine	DMT70RC	Malaria	1F40-1F45	Approved	[1]
Artemisinin SP	DMFETDK	Malaria	1F40-1F45	Approved	[1]
Artesunate	DMR27C8	Infection of P. falciparum	1F40	Approved	[1]
OZ277	DM1YB0R	Malaria	1F40-1F45	Approved	[1]
Pyronaridine	DMUWAM2	Malaria	1F40-1F45	Approved	[1]
Vanadate	DMQL0KF	Psoriatic arthritis	FA21	Phase 3	[5]
THAPSIGARGIN	DMDMQIE	N. A.	N. A.	Preclinical	[6]
Cyclopiazonic acid	DMPJ08G	Discovery agent	N.A.	Investigative	[5]

Drug(s) Metabolized By UDP-glucuronosyltransferase 2B7 (UGT2B7)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[7]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[8]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[9]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[10]
Mycophenolate mofetil	DMPQAGE	Hepatosplenic T-cell lymphoma		Approved	[11]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[9]
PITAVASTATIN CALCIUM	DM1UJO0	Dyslipidemia	5C80-5C81	Approved	[12]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[13]
Ezetimibe	DM7A8TW	Atherosclerosis	BD40	Approved	[14]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[15]

Drug(s) Metabolized By UDP-glucuronosyltransferase 1A9 (UGT1A9)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[16]
Diclofenac	DMPIHLS	Chronic renal failure	GB61.Z	Approved	[17]
Sorafenib	DMS8IFC	Adenocarcinoma	2D40	Approved	[18]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[9]
Mycophenolate mofetil	DMPQAGE	Hepatosplenic T-cell lymphoma		Approved	[19]
Propofol	DMB4OLE	Anaesthesia	9A78.6	Approved	[9]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[9]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[20]
Nateglinide	DMLK2QH	Diabetic complication	5A2Y	Approved	[9]
Haloperidol	DM96SE0	Delirium		Approved	[9]

Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zolmitriptan	DM1IB4Q	Migraine	8A80	Approved	[21]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[21]
Etoricoxib	DM6A4NW	Rheumatoid arthritis	FA20	Approved	[21]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[22]
Hesperetin	DMKER83	High blood cholesterol level	5C80.00	Approved	[23]
Stiripentol	DMMSDOY	Dravet syndrome	8A61.11	Approved	[24]
Nifedipine	DMSVOZT	Angina pectoris	BA40	Approved	[25]
Zileuton	DMVRIC2	Allergic asthma	CA23.0	Approved	[26]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[27]
Clonidine	DM6RZ9Q	Attention deficit hyperactivity disorder	6A05.Z	Approved	[28]

Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Eplerenone	DMF0NQR	Heart failure	BD10-BD13	Approved	[29]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[30]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[31]
Voriconazole	DMAOL2S	Aspergillosis	1F20	Approved	[32]
Proguanil	DMBL79I	Malaria	1F40-1F45	Approved	[33]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[33]
Loratadine	DMF3AN7	Allergy	4A80-4A85	Approved	[34]
Nelfinavir mesylate	DMFX6G8	N. A.	N. A.	Approved	[35]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[36]
Axitinib	DMGVH6N	Renal cell carcinoma	2C90	Approved	[37]

Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[30]
Thioridazine	DM35M8J	Schizophrenia	6A20	Approved	[38]
Voriconazole	DMAOL2S	Aspergillosis	1F20	Approved	[32]
Chloramphenicol	DMFXEWT	Bacterial infection	1A00-1C4Z	Approved	[39]
Capsaicin	DMGMF6V	Back pain	ME84.Z	Approved	[22]
Pentamidine	DMHZJCG	African trypanosomiasis	1F51	Approved	[33]
Stiripentol	DMMSDOY	Dravet syndrome	8A61.11	Approved	[24]
Quinine	DMSWYF5	Malaria	1F40-1F45	Approved	[33]
Desipramine	DMT2FDC	Attention deficit hyperactivity disorder	6A05.Z	Approved	[38]
Amitriptyline	DMK7F9S	Depression	6A70-6A7Z	Approved	[28]

Drug(s) Affected By Superoxide dismutase (SOD1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[40]
Haloperidol	DM96SE0	Delirium		Approved	[28]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[41]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[42]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[43]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[44]
SPI-1005	DM6XFHS	Reperfusion injury	ND56.Z	Approved	[45]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[46]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[47]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[48]

Drug(s) Affected By Catalase (CAT)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[43]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[49]
Haloperidol	DM96SE0	Delirium		Approved	[28]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[50]
Selenium	DM25CGV	N. A.	N. A.	Approved	[51]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[52]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[53]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[54]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[55]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]

Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[57]
Selenium	DM25CGV	N. A.	N. A.	Approved	[58]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[59]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[60]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[47]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[61]
Rofecoxib	DM3P5DA	Osteoarthritis	FA00-FA05	Approved	[62]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[63]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[64]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[65]

Drug(s) Affected By Chloride intracellular channel protein 1 (CLIC1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[67]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[68]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[70]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[72]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[73]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[74]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[75]

Drug(s) Affected By Interferon-inducible protein AIM2 (AIM2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[76]
Bortezomib	DMNO38U	Leukemia		Approved	[77]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[78]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[79]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]
Formaldehyde	DM7Q6M0	Discovery agent	N.A.	Investigative	[76]

Drug(s) Affected By Gasdermin-E (GSDME)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[81]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[59]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[59]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[86]

Drug(s) Affected By ATP synthase subunit g, mitochondrial (ATP5MG)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[87]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[88]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[89]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[90]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
PEITC	DMOMN31	Prostate cancer	2C82.0	Phase 2	[92]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]

Drug(s) Affected By L-lactate dehydrogenase A chain (LDHA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[94]
Adenosine	DMM2NSK	Paroxysmal supraventricular tachycardia	BC81.Z	Approved	[28]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[96]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[97]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[99]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[100]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[101]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]

Drug(s) Affected By Phosphoglycerate kinase 1 (PGK1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[103]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[104]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[105]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[67]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[101]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]

Drug(s) Affected By Myc proto-oncogene protein (MYC)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[106]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[107]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[108]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[109]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[110]
Selenium	DM25CGV	N. A.	N. A.	Approved	[111]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[112]
Trametinib	DM2JGQ3	Melanoma	2C30	Approved	[113]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[114]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[54]

Drug(s) Affected By Interleukin-1 beta (IL1B)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[115]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[116]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[117]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[118]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[43]
Lumiracoxib	DM1S4AG	Chronic renal failure	GB61.Z	Approved	[118]
Imiquimod	DM1TMA3	Alopecia areata	ED70.2	Approved	[119]
Selenium	DM25CGV	N. A.	N. A.	Approved	[58]
Ribavirin	DMEYLH9	Hepatitis C virus infection	1E51.1	Approved	[120]
Spironolactone	DM2AQ5N	Chronic heart failure	BD1Z	Approved	[121]

Drug(s) Affected By Glycophorin-A (GYPA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[122]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[123]
Midostaurin	DMI6E0R	Acute myeloid leukaemia	2A60	Approved	[124]
Teriflunomide	DMQ2FKJ	Hyperlipidaemia	5C80	Approved	[125]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[126]
Allopurinol	DMLPAOB	Gout	FA25	Approved	[28]
Resveratrol	DM3RWXL	Giant cell arteritis	4A44.2	Phase 3	[127]
phorbol 12-myristate 13-acetate	DMJWD62	Acute myeloid leukaemia	2A60	Phase 2	[128]
APIGENIN	DMI3491	Discovery agent	N.A.	Investigative	[129]
Butanoic Acid	DMTAJP7	Discovery agent	N.A.	Investigative	[130]

Drug(s) Affected By Albumin (ALB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[75]
Sulfamethoxazole	DMB08GE	Acute otitis media	AB00	Approved	[28]
Tolbutamide	DM02AWV	Advanced cancer	2A00-2F9Z	Approved	[131]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[132]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[133]
Methimazole	DM25FL8	Hyperthyroidism	5A02	Approved	[134]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[135]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[136]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[137]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[138]

Drug(s) Affected By Glyceraldehyde-3-phosphate dehydrogenase (GAPDH)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[139]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[140]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[141]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[63]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[95]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[67]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[142]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[143]

Drug(s) Affected By Cellular tumor antigen p53 (TP53)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[144]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[54]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[145]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[146]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[147]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[148]
Floxuridine	DM04LR2	Colorectal cancer	2B91.Z	Approved	[149]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[150]
Mechlorethamine	DM0CVXA	Chronic myelogenous leukaemia	2A20.0	Approved	[151]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[152]

Drug(s) Affected By Alpha-enolase (ENO1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[153]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[154]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[155]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[63]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[156]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[104]
Liothyronine	DM6IR3P	Congenital hypothyroidism		Approved	[157]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[158]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[159]

Drug(s) Affected By Glucose-6-phosphate isomerase (GPI)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[160]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[105]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[142]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[161]

Drug(s) Affected By Nucleophosmin (NPM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[162]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[154]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[141]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[163]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[164]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[164]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]

Drug(s) Affected By L-lactate dehydrogenase B chain (LDHB)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[165]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[166]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[167]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[168]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[169]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Fenofibrate	DMFKXDY	Coronary atherosclerosis		Approved	[166]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[170]

Drug(s) Affected By Annexin A2 (ANXA2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[171]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[172]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[173]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[174]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[175]
Thalidomide	DM70BU5	Adult T-cell leukemia/lymphoma		Approved	[176]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[164]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[177]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[168]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[164]

Drug(s) Affected By Profilin-1 (PFN1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[171]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[178]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[179]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[180]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[181]
Haloperidol	DM96SE0	Delirium		Approved	[142]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]

Drug(s) Affected By Small ribosomal subunit protein eS17 (RPS17)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[182]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[183]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[184]
AHPN	DM8G6O4	Discovery agent	N.A.	Investigative	[185]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Galectin-1 (LGALS1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[187]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[179]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[188]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[99]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[181]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[168]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[169]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]

Drug(s) Affected By High mobility group protein B1 (HMGB1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[162]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[117]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[165]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Romiplostim	DM3U7SZ	Thrombocytopenia	3B64	Approved	[189]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[190]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[164]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[164]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]

Drug(s) Affected By Tropomyosin alpha-1 chain (TPM1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[191]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[192]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[193]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[170]
Bortezomib	DMNO38U	Leukemia		Approved	[77]
Ethinyl Estradiol	DMODJ40	Acne vulgaris	ED80	Approved	[194]

Drug(s) Affected By Heme oxygenase 1 (HMOX1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[195]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[196]
Pantothenic acid	DM091H2	Vitamin deficiency	5B55-5B71	Approved	[197]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[198]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[116]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[57]
Selenium	DM25CGV	N. A.	N. A.	Approved	[199]
TECFIDERA	DM2OVDT	Multiple sclerosis	8A40	Approved	[200]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[201]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[202]

Drug(s) Affected By Heat shock cognate 71 kDa protein (HSPA8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[203]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[107]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[162]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[191]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[178]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[179]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[167]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[204]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[205]

Drug(s) Affected By Glucose-6-phosphate 1-dehydrogenase (G6PD)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[161]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[28]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[142]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[187]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[206]
Clavulanate	DM2FGRT	Bacteremia	1A73	Approved	[207]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[208]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[209]
Isoniazid	DM5JVS3	Latent tuberculosis infection		Approved	[210]

Drug(s) Affected By Pyruvate kinase PKM (PKM)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[171]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Epinephrine	DM3KJBC	Acute asthma	CA23	Approved	[211]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[212]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[174]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[213]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[67]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[101]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]

Drug(s) Affected By Desmoplakin (DSP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[156]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[214]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[215]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[216]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[68]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[218]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Malathion	DMXZ84M	Pediculus capitis infestation	1G00.0	Approved	[219]

Drug(s) Affected By Early growth response protein 1 (EGR1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[196]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[220]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[221]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[222]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[223]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[224]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[225]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[226]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[204]

Drug(s) Affected By Calpastatin (CAST)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[165]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[192]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[88]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[227]
Piroxicam	DMTK234	Osteoarthritis	FA00-FA05	Approved	[228]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]

Drug(s) Affected By Cysteine and glycine-rich protein 1 (CSRP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[183]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[229]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[230]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[68]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[94]

Drug(s) Affected By Filamin-A (FLNA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[231]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[209]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Rosiglitazone	DMILWZR	Chronic kidney disease	GB61	Approved	[232]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]

Drug(s) Affected By Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[162]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[141]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[95]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[214]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[177]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[101]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[233]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[234]

Drug(s) Affected By Splicing factor, proline- and glutamine-rich (SFPQ)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[162]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[229]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[142]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[94]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[235]

Drug(s) Affected By Cofilin-1 (CFL1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[191]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[155]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[167]
Haloperidol	DM96SE0	Delirium		Approved	[142]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[236]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]

Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[196]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[107]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[237]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[238]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[239]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[240]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[226]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[222]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[241]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[242]

Drug(s) Affected By ATP synthase subunit alpha, mitochondrial (ATP5F1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[142]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[243]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[244]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[245]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[246]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[177]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Niclosamide	DMJAGXQ	Cestodes infection	1F70-1F76	Approved	[89]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[170]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]

Drug(s) Affected By Large ribosomal subunit protein uL16 (RPL10)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]
Ursodeoxycholic acid	DMCUT21	Cholelithiasis	DC11	Approved	[247]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[182]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[78]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[248]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[82]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[250]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[251]

Drug(s) Affected By Microtubule-associated protein 4 (MAP4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[183]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[252]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[209]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[174]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[94]

Drug(s) Affected By DNA damage-inducible transcript 3 protein (DDIT3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[196]
Triacetin	DM0AEPG	Onychomycosis	EE12.1	Approved	[253]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[107]
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[254]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[255]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[220]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[256]
Sulindac	DM2QHZU	Acute myelogenous leukaemia	2A41	Approved	[257]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[258]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]

Drug(s) Affected By Large ribosomal subunit protein uL4 (RPL4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[259]
Decitabine	DMQL8XJ	Acute myelogenous leukaemia	2A41	Approved	[260]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[261]
Epigallocatechin gallate	DMCGWBJ	Hepatic fibrosis	DB93.0	Phase 3	[262]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[183]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[184]
Milchsaure	DM462BT	Pruritus	EC90	Investigative	[263]

Drug(s) Affected By Signal recognition particle 14 kDa protein (SRP14)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
DTI-015	DMXZRW0	Brain cancer	2A00	Approved	[264]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[265]
methyl p-hydroxybenzoate	DMO58UW	Discovery agent	N.A.	Investigative	[266]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Transgelin-2 (TAGLN2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[142]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[174]
Haloperidol	DM96SE0	Delirium		Approved	[142]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[142]

Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[267]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[268]
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[42]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[269]
Talazoparib	DM1KS78	Breast cancer	2C60-2C65	Approved	[270]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[220]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[271]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[272]
Ciprofloxacin XR	DM2NLS9	Acute gonococcal cervicitis		Approved	[273]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[274]

Drug(s) Affected By Small ribosomal subunit protein eS19 (RPS19)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[275]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[164]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[164]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Enzalutamide	DMGL19D	Prostate cancer	2C82.0	Approved	[276]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[277]
Bortezomib	DMNO38U	Leukemia		Approved	[278]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[261]
Urethane	DM7NSI0	N. A.	N. A.	Phase 4	[248]

Drug(s) Affected By Malate dehydrogenase, cytoplasmic (MDH1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[171]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[141]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[63]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[209]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[142]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[170]

Drug(s) Affected By Caspase-3 (CASP3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sevoflurane	DMC9O43	Anaesthesia	9A78.6	Approved	[279]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[280]
Lovastatin	DM9OZWQ	Arteriosclerosis	BD40	Approved	[281]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[147]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[282]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[283]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[284]
Mannitol	DMSCDY9	Bronchiectasis	CA24	Approved	[285]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[286]
Aprepitant	DM053KT	Depression	6A70-6A7Z	Approved	[287]

Drug(s) Affected By Large ribosomal subunit protein uL29 (RPL35)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[265]
AHPN	DM8G6O4	Discovery agent	N.A.	Investigative	[185]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Small ribosomal subunit protein uS4 (RPS9)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[139]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[214]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[288]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[143]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[77]
Cocaine	DMSOX7I	Anaesthesia	9A78.6	Approved	[289]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[290]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]

Drug(s) Affected By Small ribosomal subunit protein uS7 (RPS5)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[94]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[291]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]
Deguelin	DMXT7WG	Esophageal squamous cell carcinoma	2E60.1	Investigative	[292]

Drug(s) Affected By Ras GTPase-activating-like protein IQGAP1 (IQGAP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Fulvestrant	DM0YZC6	Breast cancer	2C60-2C65	Approved	[162]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[141]
Crizotinib	DM4F29C	Non-small-cell lung cancer	2C25.Y	Approved	[293]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[174]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[294]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[295]

Drug(s) Affected By ATP synthase subunit O, mitochondrial (ATP5PO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[87]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[296]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[165]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[297]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Josamycin	DMKJ8LB	Bacterial infection	1A00-1C4Z	Approved	[298]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]

Drug(s) Affected By T-complex protein 1 subunit gamma (CCT3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[191]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[167]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ursodeoxycholic acid	DMCUT21	Cholelithiasis	DC11	Approved	[247]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
DNCB	DMDTVYC	Immune System disease	4A01-4B41	Phase 2	[299]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]

Drug(s) Affected By Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[156]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[300]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[301]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[227]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[297]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]

Drug(s) Affected By Large ribosomal subunit protein eL14 (RPL14)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[191]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[161]
Tocopherol	DMBIJZ6	N. A.	N. A.	Phase 2	[82]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]

Drug(s) Affected By Puromycin-sensitive aminopeptidase (NPEPPS)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[165]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[97]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[239]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Testosterone enanthate	DMB6871	N. A.	N. A.	Approved	[302]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[70]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[295]
Menadione	DMSJDTY	Vitamin K deficiency	5B59	Approved	[165]

Drug(s) Affected By Triosephosphate isomerase (TPI1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[154]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[178]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[97]
Acocantherin	DM7JT24	Atrial fibrillation	BC81.3	Approved	[177]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[168]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]

Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein K (HNRNPK)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[183]
Cyclophosphamide	DM4O2Z7	Advanced cancer	2A00-2F9Z	Approved	[303]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[304]
Haloperidol	DM96SE0	Delirium		Approved	[142]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Ethanol	DMDRQZU	Chronic pain	MG30	Approved	[233]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[305]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[304]
PEITC	DMOMN31	Prostate cancer	2C82.0	Phase 2	[92]

Drug(s) Affected By Small ribosomal subunit protein eS8 (RPS8)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[306]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[183]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[291]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Small ribosomal subunit protein uS13 (RPS18)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[307]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[78]
Genistein	DM0JETC	Menopause symptom	GA30.0	Phase 2/3	[308]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[262]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[265]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Small ribosomal subunit protein uS15 (RPS13)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[208]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ursodeoxycholic acid	DMCUT21	Cholelithiasis	DC11	Approved	[247]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[290]
Epigallocatechin gallate	DMCGWBJ	Hepatic fibrosis	DB93.0	Phase 3	[262]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[251]
all-trans-4-oxo-retinoic acid	DMM2R1N	Discovery agent	N.A.	Investigative	[208]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]
Deguelin	DMXT7WG	Esophageal squamous cell carcinoma	2E60.1	Investigative	[292]

Drug(s) Affected By Small nuclear ribonucleoprotein Sm D2 (SNRPD2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[309]
AHPN	DM8G6O4	Discovery agent	N.A.	Investigative	[185]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Large ribosomal subunit protein uL23 (RPL23A)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[227]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[78]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[310]
Epigallocatechin gallate	DMCGWBJ	Hepatic fibrosis	DB93.0	Phase 3	[262]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[265]
Milchsaure	DM462BT	Pruritus	EC90	Investigative	[263]

Drug(s) Affected By Small ribosomal subunit protein eS6 (RPS6)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[311]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[221]
Crizotinib	DM4F29C	Non-small-cell lung cancer	2C25.Y	Approved	[312]
Glucosamine	DM4ZLFD	Osteoarthritis	FA00-FA05	Approved	[313]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[214]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[314]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[315]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[316]
Capivasertib	DM9SKW8	Breast cancer	2C60-2C65	Approved	[317]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]

Drug(s) Affected By Small ribosomal subunit protein eS28 (RPS28)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[191]
Ursodeoxycholic acid	DMCUT21	Cholelithiasis	DC11	Approved	[247]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[318]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[261]
Vorinostat	DMWMPD4	Adult acute monocytic leukemia		Approved	[319]
Epigallocatechin gallate	DMCGWBJ	Hepatic fibrosis	DB93.0	Phase 3	[262]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[320]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[262]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[321]

Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase A (PPIA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[171]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[221]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[322]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Ibuprofen	DM8VCBE	Dysmenorrhea	GA34.3	Approved	[168]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]

Drug(s) Affected By Actin, cytoplasmic 2 (ACTG1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[252]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[97]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[68]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[227]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[161]

Drug(s) Affected By Elongation factor 1-alpha 1 (EEF1A1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[156]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[212]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[323]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[324]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[101]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Menthol	DMG2KW7	Back pain	ME84.Z	Approved	[143]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]

Drug(s) Affected By Transgelin (TAGLN)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[325]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[326]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[327]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[325]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[328]
Thioridazine	DM35M8J	Schizophrenia	6A20	Approved	[325]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[325]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[329]
Erythromycin	DM4K7GQ	Acne vulgaris	ED80	Approved	[327]

Drug(s) Affected By Peroxiredoxin-1 (PRDX1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[330]
Etretinate	DM2CZFA	Keratosis	ED56	Approved	[95]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[202]
obeticholic acid	DM3Q1SM	Primary biliary cholangitis	DB96.1	Approved	[63]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[223]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[324]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[331]
Calcitriol	DM8ZVJ7	Congenital alopecia	LC30	Approved	[324]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]

Drug(s) Affected By Large ribosomal subunit protein eL18 (RPL18)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[142]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[214]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[183]
bisphenol A	DM2ZLD7	Discovery agent	N.A.	Investigative	[184]
chloropicrin	DMSGBQA	Discovery agent	N.A.	Investigative	[186]

Drug(s) Affected By Serine/arginine-rich splicing factor 4 (SRSF4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[212]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[212]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[70]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[332]
PMID28460551-Compound-2	DM4DOUB	N. A.	N. A.	Patented	[93]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[183]
COUMARIN	DM0N8ZM	Discovery agent	N.A.	Investigative	[183]
Apicidin	DM83WVF	Solid tumour/cancer	2A00-2F9Z	Investigative	[333]

Drug(s) Affected By Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[196]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[334]
Nitric Oxide	DM1RBYG	Hypertension	BA00-BA04	Approved	[335]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[336]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[337]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Troglitazone	DM3VFPD	Diabetic complication	5A2Y	Approved	[338]
Penicillamine	DM40EF6	Cystinuria	5C60.2	Approved	[224]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[324]
Acetic Acid, Glacial	DM4SJ5Y	infection in the ear canal	AA0Y	Approved	[104]

Drug(s) Affected By Heterogeneous nuclear ribonucleoprotein D0 (HNRNPD)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[339]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[165]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[340]
Demecolcine	DMCZQGK	Solid tumour/cancer	2A00-2F9Z	Approved	[76]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[142]

Drug(s) Affected By Interleukin-18 (IL18)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[115]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[139]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[54]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[341]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[342]
Ergotidine	DM78IME	Osteoarthritis	FA00-FA05	Approved	[343]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[169]
Propofol	DMB4OLE	Anaesthesia	9A78.6	Approved	[344]
Sevoflurane	DMC9O43	Anaesthesia	9A78.6	Approved	[344]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]

Drug(s) Affected By Kelch-like ECH-associated protein 1 (KEAP1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[345]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[334]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[212]
Hydroquinone	DM6AVR4	Melasma	ED60.1	Approved	[342]
Clodronate	DM9Y6X7	Hypercalcaemia	5B91.0	Approved	[159]
Cidofovir	DMA13GD	Cytomegalovirus infection	1D82	Approved	[159]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[159]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[346]
Ifosfamide	DMCT3I8	Adult central nervous system germ cell tumor		Approved	[159]

Drug(s) Affected By Splicing factor 1 (SF1)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[139]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[347]
Hydroxyflutamide	DMGIZF5	Prostate cancer	2C82.0	Approved	[348]
Cupric Sulfate	DMP0NFQ	Fungal infection	1F29-1F2F	Approved	[217]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[94]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[349]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]

Drug(s) Affected By Nuclear factor erythroid 2-related factor 2 (NFE2L2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[350]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[198]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[107]
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[43]
Selenium	DM25CGV	N. A.	N. A.	Approved	[82]
TECFIDERA	DM2OVDT	Multiple sclerosis	8A40	Approved	[351]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[352]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[60]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Furazolidone	DM3P6V7	Diarrhea	ME05.1	Approved	[353]

Drug(s) Affected By Dihydropyrimidinase-related protein 2 (DPYSL2)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[354]
Isotretinoin	DM4QTBN	Acne vulgaris	ED80	Approved	[209]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[98]
Leflunomide	DMR8ONJ	Arthritis	FA20	Approved	[68]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[83]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Benzatropine	DMF7EXL	Parkinsonian disorder		Approved	[142]
Sodium lauryl sulfate	DMLJ634	Constipation	DD91.1	Approved	[355]

Drug(s) Affected By Heterochromatin protein 1-binding protein 3 (HP1BP3)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[340]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Zoledronate	DMIXC7G	Adenocarcinoma	2D40	Approved	[77]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[74]
Acetaminophen	DMUIE76	Allergic rhinitis	CA08.0	Approved	[161]
Nicotine	DMWX5CO	Lung cancer	2C25.0	Approved	[356]
(+)-JQ1	DM1CZSJ	Testicular cancer	2C80	Phase 1	[357]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]

Drug(s) Affected By Far upstream element-binding protein 2 (KHSRP)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Quercetin	DM3NC4M	Obesity	5B81	Approved	[178]
Marinol	DM70IK5	Anorexia nervosa cachexia	6B80	Approved	[158]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[101]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[102]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[358]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[359]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[91]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[80]
PMID28870136-Compound-52	DMFDERP	N. A.	N. A.	Patented	[262]

Drug(s) Affected By Bile acid receptor (NR1H4)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Hydrogen peroxide	DM1NG5W	Infectious disease	1A00-CA43.1	Approved	[334]
Nitrendipine	DM21C09	Hypertension	BA00-BA04	Approved	[360]
Deoxycholic acid	DM3GYAL	Subcutaneous fat disorder	EF02	Approved	[361]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[56]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[362]
Nefazodone	DM4ZS8M	Major depressive disorder	6A70.3	Approved	[363]
Nisoldipine	DM7ISKJ	Hypertension	BA00-BA04	Approved	[360]
Cholic Acid	DM7OKQV	Cholelithiasis	DC11	Approved	[361]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[364]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[69]

Drug(s) Affected By Alpha-ketoglutarate-dependent dioxygenase FTO (FTO)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[66]
Valproate	DMCFE9I	Epilepsy	8A60-8A68	Approved	[84]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[71]
Temozolomide	DMKECZD	Adenocarcinoma	2D40	Approved	[85]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[259]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[365]
Arsenic	DMTL2Y1	N. A.	N. A.	Approved	[366]
TAK-243	DM4GKV2	Solid tumour/cancer	2A00-2F9Z	Phase 1	[249]
Benzo(a)pyrene	DMN7J43	N. A.	N. A.	Phase 1	[69]
COUMARIN	DM0N8ZM	Discovery agent	N.A.	Investigative	[183]

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Sarcoplasmic/endoplasmic reticulum calcium ATPase (ATP2A)	TTZVSJ2	NOUNIPROTAC	Inhibitor	[1]

Drug-Metabolizing Enzyme (DME)

DME Name	DME ID	UniProt ID	MOA	REF
UDP-glucuronosyltransferase 2B7 (UGT2B7)	DEB3CV1	UD2B7_HUMAN	Substrate	[2]
UDP-glucuronosyltransferase 1A9 (UGT1A9)	DE85D2P	UD19_HUMAN	Substrate	[2]

Drug Off-Target (DOT)

DOT Name	DOT ID	UniProt ID	Interaction	REF
Actin, cytoplasmic 2 (ACTG1)	OTH4V7VQ	ACTG_HUMAN	Protein Interaction/Cellular Processes	[3]
Albumin (ALB)	OTVMM513	ALBU_HUMAN	Protein Interaction/Cellular Processes	[3]
Alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1)	OTV57BZD	AL7A1_HUMAN	Protein Interaction/Cellular Processes	[3]
Alpha-enolase (ENO1)	OTB1KWJS	ENOA_HUMAN	Protein Interaction/Cellular Processes	[3]
Alpha-ketoglutarate-dependent dioxygenase FTO (FTO)	OTXML85Y	FTO_HUMAN	Protein Interaction/Cellular Processes	[3]
Annexin A2 (ANXA2)	OTFNS0CC	ANXA2_HUMAN	Protein Interaction/Cellular Processes	[3]
ATP synthase subunit alpha, mitochondrial (ATP5F1A)	OT3FZDLX	ATPA_HUMAN	Protein Interaction/Cellular Processes	[3]
ATP synthase subunit g, mitochondrial (ATP5MG)	OTD569IJ	ATP5L_HUMAN	Protein Interaction/Cellular Processes	[3]
ATP synthase subunit O, mitochondrial (ATP5PO)	OTU3MCTN	ATPO_HUMAN	Protein Interaction/Cellular Processes	[3]
Bile acid receptor (NR1H4)	OTWZLPTB	NR1H4_HUMAN	Gene/Protein Processing	[4]

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