General Information of Disease (ID: DISXL1WY)

Disease Name Dementia
Synonyms dementia (disease); dementia
Disease Class 6D80-6D8Z: Dementia
Definition Loss of intellectual abilities interfering with an individual's social and occupational functions. Causes include Alzheimer's disease, brain injuries, brain tumors, and vascular disorders.
Disease Hierarchy
DISH2ERD: Cognitive impairment
DISXL1WY: Dementia
ICD Code
ICD-11
ICD-11: 6D80-6D86
Disease Identifiers
MONDO ID
MONDO_0001627
MESH ID
D003704
UMLS CUI
C0497327
MedGen ID
99229
HPO ID
HP:0000726
SNOMED CT ID
52448006

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Cyclandelate DMO0R76 Approved Small molecular drug [1]
Indeloxazine DMWO3N6 Approved Small molecular drug [1]
Oxiracetam DMYVRAE Approved Small molecular drug [1]
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This Disease is Treated as An Indication in 12 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
NAV5001 DMRSI1M Phase 3 NA [2]
PF-4494700 DMJ7IKW Phase 3 Small molecular drug [3]
MEM-1003 DMYZU6G Phase 2a Small molecular drug [4]
DAS-431 DMM3BPL Phase 2 NA [5]
GSK239512 DMBJMZC Phase 2 Small molecular drug [6]
K-828-AB DMJLNZQ Phase 2 NA [7]
Neu-P11 DMIQDFW Phase 2 Small molecular drug [8]
PQ-912 DMM6J5Z Phase 2 NA [9]
R-phenserine DM4L5VJ Phase 2 NA [8]
BIIB080 DM6QH3U Phase 1/2 NA [10]
B7-2/GM-CSF DM0LKHV Phase 1 Small molecular drug [11]
MK-3134 DM5EFPS Phase 1 NA [12]
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⏷ Show the Full List of 12 Drug(s)
This Disease is Treated as An Indication in 5 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
AIT-034 DMWKYDB Discontinued in Phase 3 NA [13]
ABT-089 DM8DT7U Discontinued in Phase 2 Small molecular drug [14]
RX-77368 DMR0K85 Discontinued in Phase 2 Small molecular drug [15]
LY-274614 DMG79NT Terminated Small molecular drug [16]
Org-31433 DMFE0S5 Terminated Small molecular drug [17]
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This Disease is Treated as An Indication in 10 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
4-fluoroselegiline DMRC49E Investigative NA [18]
AS-1522489-00 DM7A8PX Investigative NA [19]
Ciproxifan DM9N8WM Investigative Small molecular drug [20]
DBT-066 DMFYCQ1 Investigative NA [21]
DW-514 DMGGIJA Investigative NA [22]
ENDG-6010 DMTTOLD Investigative NA [22]
HF-0420 DM3AYLV Investigative NA [22]
OG-19 DM612KO Investigative NA [22]
OG-45 DMNZTPT Investigative NA [22]
RP-4000 DMVP8CT Investigative NA [22]
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⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 86 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
CHAT TTKYFSB Limited Biomarker [23]
DNMT1 TT6S2FE Limited Genetic Variation [24]
F11 TTDM4ZU Limited Biomarker [25]
GRK5 TTTCXO0 Limited Genetic Variation [26]
MCOLN1 TT9XBVO Limited Biomarker [27]
OPA1 TTTU49Q Limited Genetic Variation [28]
SNCG TT5TQNZ Limited Genetic Variation [29]
ATP7B TTOPO51 moderate Biomarker [30]
CLN6 TTJCOQ7 moderate Genetic Variation [31]
CTSF TTJOKD1 moderate Biomarker [31]
GBA TT1B5PU moderate Biomarker [32]
HTT TTIWZ0O moderate Altered Expression [33]
MECP2 TTTAU9R moderate Altered Expression [34]
NAGLU TTDM6HZ moderate Biomarker [35]
P2RY11 TTYXPCO moderate Biomarker [24]
TBK1 TTMP03S moderate Genetic Variation [36]
ABCA1 TTJW1GN Strong Biomarker [37]
ABCG1 TTMWDGU Strong Biomarker [38]
APOC3 TTXOZQ1 Strong Biomarker [39]
ARSA TTYQANR Strong Biomarker [40]
ATXN2 TTPQJ7P Strong Biomarker [41]
BACE2 TT69DB8 Strong Genetic Variation [42]
CASP6 TTKW4ML Strong Biomarker [43]
CD4 TTN2JFW Strong Altered Expression [44]
CETP TTFQAYR Strong Biomarker [45]
CHIT1 TTDYX6T Strong Altered Expression [46]
CHM TTOA18V Strong Biomarker [47]
CHRNA4 TT4H1MQ Strong Biomarker [48]
CHRNB2 TT5KPZR Strong Biomarker [49]
CIT TT3BKTU Strong Biomarker [50]
CPE TTXPWO6 Strong Genetic Variation [51]
CRP TTWRN6M Strong Biomarker [52]
CSF1R TT7MRDV Strong Genetic Variation [53]
CSPG4 TT7MYXI Strong Biomarker [54]
DLG4 TT9PB26 Strong Altered Expression [55]
DPP4 TTDIGC1 Strong Biomarker [56]
DRD3 TT4C8EA Strong Genetic Variation [57]
EBP TT4VQZX Strong Biomarker [58]
EPHX2 TT7WVHI Strong Altered Expression [59]
FDXR TT3W4IX Strong Genetic Variation [60]
FUS TTKGYZ9 Strong Biomarker [61]
GNE TT4DP5S Strong Biomarker [62]
GPR39 TTTPCNU Strong Biomarker [63]
HSD11B1 TTN7BL9 Strong Biomarker [64]
HSPB8 TTY0OJN Strong Altered Expression [65]
HTR1A TTSQIFT Strong Biomarker [66]
HTR2A TTJQOD7 Strong Genetic Variation [67]
HTR6 TTJS8PY Strong Biomarker [68]
HTRA1 TT8POQR Strong Biomarker [69]
IAPP TTHN8EM Strong Biomarker [70]
INPP5D TTTP2Z1 Strong Biomarker [71]
KLK7 TTE6GTB Strong Biomarker [72]
LANCL1 TTZW8NS Strong Biomarker [73]
LIMK1 TTWL9TY Strong Biomarker [74]
LIPG TTHSZXO Strong Altered Expression [75]
MFGE8 TT1GLAJ Strong Biomarker [76]
NOTCH3 TTVX7IA Strong Genetic Variation [77]
PDE9A TTZOEBC Strong Altered Expression [78]
PDXP TT9UYG4 Strong Genetic Variation [79]
PIN1 TTJNTSI Strong Biomarker [80]
PLA2G7 TTDNFMT Strong Altered Expression [81]
PLD1 TT3T17P Strong Biomarker [82]
PPP3CA TTA4LDE Strong Biomarker [83]
PREP TTNGKET Strong Biomarker [84]
PSEN2 TTWN3F4 Strong Genetic Variation [85]
QPCT TTJ7YTV Strong Altered Expression [86]
SCD TT6RIOV Strong Biomarker [87]
SF3B1 TTL2WUI Strong Genetic Variation [88]
SGCA TTS9Q5V Strong Biomarker [89]
SIGMAR1 TT5TPI6 Strong Genetic Variation [90]
SLC18A3 TTV8KWS Strong Biomarker [91]
SLC1A2 TT2F078 Strong Biomarker [92]
SLC1A3 TT8WRDA Strong Biomarker [93]
SLC33A1 TTL69WB Strong Biomarker [94]
SLC6A3 TTVBI8W Strong Genetic Variation [95]
SLC6A4 TT3ROYC Strong Biomarker [96]
SORD TTLSRBZ Strong Biomarker [97]
SQSTM1 TTOT2RY Strong Biomarker [98]
STAR TTEI40H Strong Biomarker [54]
STK16 TTFGN19 Strong Biomarker [99]
TPP1 TTOVYPT Strong Biomarker [100]
TREM2 TTQRMSJ Strong Genetic Variation [101]
TRPM2 TTEBMN7 Strong Biomarker [102]
TXNIP TTTLDZK Strong Biomarker [103]
UGCG TTPHEX3 Strong Biomarker [104]
GRN TT0LWE3 Definitive Genetic Variation [105]
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⏷ Show the Full List of 86 DTT(s)
This Disease Is Related to 7 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
ABCD1 DTKM9DZ Limited Genetic Variation [106]
ABCA7 DTDVSJA Strong Genetic Variation [107]
ABCB6 DTF9Y2V Strong Biomarker [108]
SLC17A6 DT5LHCR Strong Altered Expression [109]
SLC17A7 DTNK0FR Strong Altered Expression [92]
SLC30A6 DTKPRIL Strong Biomarker [110]
SLC9A8 DTNY0C2 Strong Biomarker [111]
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⏷ Show the Full List of 7 DTP(s)
This Disease Is Related to 9 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
THOP1 DE95LJC Limited Genetic Variation [112]
SMOX DEOH5V3 moderate Genetic Variation [113]
AKR1C4 DEAJN47 Strong Biomarker [114]
GLS DE3E0VT Strong Biomarker [115]
NDUFS3 DE741FI Strong Genetic Variation [116]
PARK7 DEPOVCH Strong Genetic Variation [117]
PER1 DE9HF0I Strong Biomarker [118]
PON2 DEHJU7E Strong Genetic Variation [119]
SULT1A1 DEYWLRK Strong Biomarker [120]
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⏷ Show the Full List of 9 DME(s)
This Disease Is Related to 218 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACY1 OT9WU7X3 Limited Biomarker [121]
ADI1 OT8IOD03 Limited Genetic Variation [122]
AGPS OTFBFPV4 Limited Biomarker [123]
APOC1 OTA58CED Limited Genetic Variation [124]
CHMP2B OTZA7RJB Limited Genetic Variation [125]
COLQ OT4BHUGQ Limited Biomarker [126]
COX2 OTTMVBJJ Limited Genetic Variation [127]
CSMD1 OTIVDSC4 Limited Genetic Variation [112]
CSMD2 OT541Z3W Limited Genetic Variation [112]
CST3 OTNZ6AO4 Limited Biomarker [128]
DCTN1 OT5B51FJ Limited Genetic Variation [129]
FLNB OTPCOYL6 Limited Biomarker [130]
ITIH4 OT460OO1 Limited Biomarker [131]
JPH3 OTHTJO2I Limited Genetic Variation [132]
LAD1 OT6YGTVX Limited Biomarker [126]
LRP10 OT8490HT Limited Genetic Variation [133]
LRRC37A OT41U0KO Limited Genetic Variation [134]
MEF2C OTZGF1Y5 Limited Altered Expression [135]
NPC2 OTE9UEJC Limited Genetic Variation [136]
NXF1 OTEFHXG6 Limited Biomarker [130]
PTCRA OTQTO5QZ Limited Biomarker [25]
SEC14L2 OTJST64D Limited Biomarker [130]
SNCAIP OTH8VNOK Limited Genetic Variation [137]
SNCB OTELSEK6 Limited Genetic Variation [29]
SPG21 OTMKJSYS Limited Genetic Variation [138]
SPON1 OTC06MY4 Limited Genetic Variation [139]
ST3GAL4 OTNENJZQ Limited Biomarker [140]
PAEP OTQA0NV4 Disputed Biomarker [141]
PICALM OTQVRPMQ Disputed Genetic Variation [142]
ATP13A2 OTKWBUGK moderate Genetic Variation [143]
CERS1 OT6EYRM3 moderate Genetic Variation [144]
CFDP1 OTXY7J96 moderate Biomarker [145]
CHI3L1 OT2Z7VJH moderate Altered Expression [146]
CISD2 OTVS7S2H moderate Genetic Variation [147]
DPP6 OTWW3H0K moderate Biomarker [148]
EIF4G2 OTEO98CR moderate Biomarker [145]
FMR1 OTWEV0T5 moderate Genetic Variation [149]
GEMIN4 OTX7402E moderate Biomarker [145]
HFE OTDD93KB moderate Genetic Variation [150]
NECTIN2 OTIE0W6O moderate Genetic Variation [113]
OSBPL1A OTQ33OQV moderate Genetic Variation [113]
PDC OT1UUVYY moderate Genetic Variation [151]
PPP2R2B OTSFVC82 moderate Genetic Variation [152]
PSMD2 OT6HZHN7 moderate Biomarker [145]
SDHB OTRE1M1T moderate Biomarker [97]
SPAST OTIF3AJI moderate Genetic Variation [153]
ABCG4 OT2XJIOG Strong Biomarker [38]
ACOT7 OT7C68YV Strong Altered Expression [154]
ACTBL2 OTD6B81U Strong Altered Expression [154]
ADAMTS2 OTTK22NO Strong Biomarker [141]
ADSL OTSNJALL Strong Biomarker [155]
AKAP6 OTN59BZS Strong Biomarker [156]
ANKK1 OT0OM1O0 Strong Genetic Variation [157]
ARMH1 OTTJC0D6 Strong Biomarker [73]
ASAH2 OT47TIF3 Strong Biomarker [158]
ASTN2 OTF0W2FJ Strong Biomarker [159]
ASXL1 OTX931AW Strong Genetic Variation [88]
ATF7IP OTU6ZA7F Strong Biomarker [160]
ATN1 OTNZFLKY Strong Genetic Variation [161]
ATP2B3 OT9DIEOP Strong Biomarker [162]
ATPAF2 OTOMEQX6 Strong Biomarker [163]
BPIFA2 OTLFSDZD Strong Biomarker [164]
BRI3 OT1RWIH7 Strong Biomarker [165]
CA11 OT8RX3AJ Strong Altered Expression [166]
CABIN1 OT4G5CIK Strong Biomarker [167]
CACUL1 OT6P1ZVP Strong Biomarker [168]
CCL4 OT6B8P25 Strong Biomarker [169]
CCL4L2 OTDBSXOU Strong Altered Expression [170]
CCS OTXHT3QO Strong Biomarker [171]
CD2AP OTC76KQM Strong Genetic Variation [172]
CDR2 OTD3ZJST Strong Biomarker [75]
CHCHD10 OTCDHAM6 Strong Genetic Variation [173]
CHCHD2 OTL5PA3Y Strong Biomarker [174]
CHD2 OTRKL6YC Strong Biomarker [174]
CIAO3 OT0V91PK Strong Biomarker [175]
CLDN5 OTUX60YO Strong Altered Expression [176]
CLSTN2 OT2PJYHX Strong Genetic Variation [177]
CNMD OTHND8EL Strong Biomarker [166]
COL25A1 OT7M23Z9 Strong Biomarker [178]
COL4A1 OTL6D1YE Strong Genetic Variation [179]
COL4A2 OTJK1LKN Strong Biomarker [180]
CP OTM8JE4Y Strong Biomarker [181]
CRTAP OT53H5U6 Strong Biomarker [182]
CRYGD OTW29JC4 Strong Altered Expression [183]
CYFIP2 OTCAY35T Strong Altered Expression [184]
CYTIP OTRJ3ZC5 Strong Biomarker [182]
DBN1 OTZVKG8A Strong Altered Expression [185]
DHDDS OTVLYBUS Strong Biomarker [186]
DHX40 OTOL02QN Strong Biomarker [187]
DSC3 OTYG47F8 Strong Biomarker [188]
DSPP OT1TYNDN Strong Genetic Variation [189]
DST OTHZBM4X Strong Biomarker [190]
DYM OTQ670WI Strong Biomarker [191]
EBNA1BP2 OTBRVMZH Strong Biomarker [73]
EDAR OT3W2UQS Strong Genetic Variation [192]
EEF1A2 OT9Z23K5 Strong Biomarker [193]
EIF4G1 OT2CF1E6 Strong Biomarker [194]
EPM2A OTJU4IAG Strong Genetic Variation [195]
ERVW-1 OTWV8DXJ Strong Genetic Variation [196]
ESCO1 OTZ9P12A Strong Biomarker [197]
FAM72A OTBZYSR3 Strong Biomarker [198]
FAM72B OT6AOG64 Strong Biomarker [198]
FANCB OTMZTXB5 Strong Biomarker [199]
FASTK OTTHFZMP Strong Genetic Variation [200]
FASTKD2 OTD635WX Strong Biomarker [201]
FBXW8 OTJG15EO Strong Biomarker [159]
FHL5 OT6C00Z1 Strong Altered Expression [154]
FMN2 OTUY7BSV Strong Genetic Variation [202]
FNDC5 OT5CSK9X Strong Biomarker [203]
GCA OTAJ7ZHG Strong Genetic Variation [204]
GDF1 OTZ1VRBH Strong Genetic Variation [144]
GLRA2 OTDQ0KW7 Strong Biomarker [205]
GLS2 OT08MSHL Strong Biomarker [206]
GYPC OTOEDR7O Strong Biomarker [207]
HARS1 OTHOEOTS Strong Genetic Variation [161]
HGS OTCYYCAC Strong Genetic Variation [161]
HHEX OTLIUVYX Strong Biomarker [208]
INPP5K OTQFLQKA Strong Biomarker [209]
INSRR OT3F75WA Strong Biomarker [210]
INTS11 OTOFT19G Strong Biomarker [211]
IRF6 OTKJ44EV Strong Biomarker [209]
KCNIP3 OTCQPEM4 Strong Biomarker [212]
KIDINS220 OTLBH2MA Strong Genetic Variation [213]
KLHDC2 OTBHH882 Strong Biomarker [214]
KLK10 OTD573EL Strong Biomarker [72]
LGI1 OTPS77HO Strong Biomarker [215]
LRP8 OTZ71YV2 Strong Genetic Variation [216]
LRPAP1 OT6DVD2Q Strong Genetic Variation [217]
LY6E OTMG16BZ Strong Genetic Variation [218]
MAP2 OT6UYT3X Strong Biomarker [219]
MBD5 OTFHT4MO Strong Genetic Variation [220]
MOK OTQK7M9V Strong Genetic Variation [221]
MPZL2 OTKFNDUI Strong Genetic Variation [222]
NAA50 OTFJ8S47 Strong Genetic Variation [223]
NANOS3 OTGX9IQU Strong Altered Expression [224]
NBEAL2 OTMCAXWR Strong Biomarker [225]
NCSTN OT5QBTA4 Strong Genetic Variation [226]
NDUFAB1 OTF906UR Strong Biomarker [227]
NFATC3 OTYOORME Strong Biomarker [228]
NFIA OTDHQ9CG Strong Biomarker [197]
NFIB OTX94PD0 Strong Biomarker [197]
NFIC OTLMCUIB Strong Biomarker [197]
NFIX OT1DPZAE Strong Biomarker [197]
NHS OTKE8QAT Strong Biomarker [229]
NINJ2 OTUG1AOV Strong Genetic Variation [230]
NPC1 OTRIPICX Strong Genetic Variation [231]
NPS OTEG25A2 Strong Biomarker [232]
NRGN OTVGE10W Strong Biomarker [233]
NUP214 OTWEA19O Strong Biomarker [167]
OLFM1 OTOYPEWW Strong Biomarker [178]
OXT OT48M72Z Strong Genetic Variation [234]
PAFAH1B1 OT9T2TCJ Strong Genetic Variation [88]
PDYN OTEJ6430 Strong Biomarker [235]
PFN1 OTHTGA1H Strong Genetic Variation [236]
PHLPP1 OTIFXW8D Strong Biomarker [237]
PINK1 OT50NR57 Strong Genetic Variation [238]
PITX3 OTE2KT8P Strong Genetic Variation [239]
PKNOX1 OTUDMNHX Strong Altered Expression [240]
PLA1A OT2IXYNX Strong Genetic Variation [241]
PLA2G6 OT5FL0WU Strong Genetic Variation [242]
PLEKHG5 OTL0S21W Strong Genetic Variation [243]
PLP1 OT8CM9CX Strong Genetic Variation [79]
PNN OT0HXICH Strong Genetic Variation [244]
POLE OTFM3MMU Strong Genetic Variation [245]
POLE3 OTOELRF6 Strong Biomarker [198]
POTEM OT7L2HGH Strong Altered Expression [154]
PRKAR1B OT777OHS Strong Genetic Variation [246]
PSMD7 OT7PZZ4K Strong Biomarker [73]
PSPH OTV1PVAX Strong Biomarker [164]
PSPN OT54LLZJ Strong Biomarker [164]
RABEPK OTCZSREH Strong Biomarker [73]
RAP1GDS1 OTH70UHD Strong Biomarker [247]
RAPGEF5 OT53VS75 Strong Biomarker [248]
RBM8A OT5SR6G0 Strong Genetic Variation [249]
RCN1 OT3JBGAG Strong Biomarker [250]
RELN OTLKMW1O Strong Altered Expression [251]
REM1 OTUXL0HC Strong Biomarker [252]
RIDA OTW4098I Strong Biomarker [164]
RIN3 OT5Z6F8O Strong Biomarker [253]
RPL29 OTUFIBJL Strong Biomarker [254]
RUNX1T1 OT30DED5 Strong Biomarker [114]
SAR1B OT0JZOMY Strong Genetic Variation [255]
SDS OT5WTJ2M Strong Biomarker [97]
SEL1L OTC0FB7T Strong Genetic Variation [256]
SERPINI1 OTUJHIJW Strong Biomarker [257]
SEZ6L2 OTUIKN2I Strong Biomarker [99]
SFPQ OTLCIAPJ Strong Biomarker [258]
SFTPC OTIZJD09 Strong Genetic Variation [259]
SH2B1 OTJZO2CI Strong Biomarker [260]
SIT1 OT7MDF09 Strong Biomarker [261]
SMCP OTXKY794 Strong Biomarker [54]
SNTA1 OTUICTGZ Strong Genetic Variation [262]
SPG11 OTZ7LJX4 Strong Genetic Variation [263]
SPTLC1 OTN0Z98K Strong Biomarker [264]
SRPX OT5B9LXS Strong Genetic Variation [244]
SRSF5 OTC5WP98 Strong Genetic Variation [161]
ST13 OTNML6UP Strong Biomarker [254]
STH OTK8ULTH Strong Genetic Variation [265]
STXBP3 OTTTYMAQ Strong Biomarker [164]
SUCLA2 OTMZD4PW Strong Biomarker [266]
SYNJ1 OTTE02XC Strong Biomarker [267]
TAOK2 OTNUMOZ1 Strong Biomarker [99]
TBCA OTCCWMGK Strong Genetic Variation [268]
TBP OT6C0S52 Strong Genetic Variation [269]
TCEA1 OTBFO594 Strong Biomarker [205]
TGDS OTEOFLOS Strong Biomarker [270]
TIGAR OTR7NMRJ Strong Altered Expression [184]
TIMP4 OT8A68SW Strong Altered Expression [271]
TMEM54 OTPQEFR0 Strong Biomarker [168]
TOM1L2 OTUXXUH8 Strong Genetic Variation [163]
TOMM40 OTZDQ29F Strong Genetic Variation [272]
TPI1 OT14KP4B Strong Biomarker [273]
TPSG1 OTDESHKT Strong Biomarker [274]
TRIM2 OT0V1YVC Strong Biomarker [275]
TSHZ1 OTYQ9ECW Strong Biomarker [276]
AARS2 OTOB0KSG Definitive Biomarker [277]
C19orf12 OTVSJ1AR Definitive Biomarker [278]
FPGT-TNNI3K OTJ6CWUN Definitive Biomarker [279]
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⏷ Show the Full List of 218 DOT(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
2 ClinicalTrials.gov (NCT01950455) Evaluation of the Diagnostic Efficacy and Safety of [123I]NAV5001 as an Imaging Agent to Aid in the Diagnosis of Parkinsonian Syndromes. U.S. National Institutes of Health.
3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 8317).
4 Efficacy of MEM 1003, a novel calcium channel blocker, in delay and trace eyeblink conditioning in older rabbits. Neurobiol Aging. 2007 May;28(5):766-73.
5 The SAGE Handbook of Healthcare, Decision Resources Inc. Page(548).
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11 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028844)
12 ClinicalTrials.gov (NCT00887601) BOLD Functional Magnetic Resonance Imaging (fMRI) and Cerebral Blood Flow Measurements as Biomarkers for Cognition Enhancing Drugs (3134-006). U.S. National Institutes of Health.
13 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800007698)
14 Emerging drugs for attention-deficit/hyperactivity disorder. Expert Opin Emerg Drugs. 2007 Sep;12(3):423-34.
15 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001316)
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17 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003509)
18 Multiple, small dose administration of (-)deprenyl enhances catecholaminergic activity and diminishes serotoninergic activity in the brain and these effects are unrelated to MAO-B inhibition. Arch Int Pharmacodyn Ther. 1994 Jul-Aug;328(1):1-15.
19 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 935).
20 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1265).
21 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 2843).
22 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
23 Transmembrane delivery and biological effect of human growth hormone via a phage displayed peptide in vivo and in vitro.J Pharm Sci. 2010 Dec;99(12):4880-91. doi: 10.1002/jps.22203.
24 EIF3G is associated with narcolepsy across ethnicities.Eur J Hum Genet. 2015 Nov;23(11):1573-80. doi: 10.1038/ejhg.2015.4. Epub 2015 Feb 11.
25 Midregional Proenkephalin A and N-terminal Protachykinin A are decreased in the cerebrospinal fluid of patients with dementia disorders and acute neuroinflammation.J Neuroimmunol. 2010 Apr 15;221(1-2):62-7. doi: 10.1016/j.jneuroim.2010.02.004. Epub 2010 Mar 5.
26 Role of G-protein coupled receptor kinase 5 gene in cognitive impairment in Parkinson's disease.Psychiatry Res. 2015 Dec 30;230(3):975-7. doi: 10.1016/j.psychres.2015.11.026. Epub 2015 Nov 17.
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