Details of Disease

General Information of Disease (ID: DIS0RK9Z)

• Disease Name: Dilated cardiomyopathy 1A
• Synonyms: cardiomyopathy, congestive; cardiomyopathy, dilated, 1A; cardiomyopathy, dilated, with conduction defect 1; cardiomyopathy, idiopathic dilated; cardiomyopathy, familial idiopathic; dilated cardiomyopathy 1A; LMNA familial isolated dilated cardiomyopathy; familial isolated dilated cardiomyopathy caused by mutation in LMNA; dilated cardiomyopathy type 1A; cardiomyopathy, dilated, type 1A; dilated cardiomyopathy with conduction defect 1; CDCD1; familial dilated cardiomyopathy with conduction defect due to LMNA mutation; cardiomyopathy dilated with conduction defect type 1
• Definition: Familial dilated cardiomyopathy with conduction defect due to LMNA mutation is a rare familial dilated cardiomyopathy characterized by left ventricular enlargement and/or reduced systolic function preceded or accompanied by significant conduction system disease and/or arrhythmias including bradyarrhythmias, supraventricular or ventricular arrhythmias. Disease onset is usually in early to mid-adulthood. Sudden cardiac death may occur and may be the presenting symptom. In some cases, it is associated with skeletal myopathy and elevated serum creatine kinase.
• Disease Hierarchy:
  DIS6SVEE: Syndromic disease
  DISBHDU9: Familial dilated cardiomyopathy
  DIS0RK9Z: Dilated cardiomyopathy 1A
• Disease Identifiers:
  MONDO ID: MONDO_0007269
  MESH ID: D002311
  UMLS CUI: C1449563
  OMIM ID: 115200
  MedGen ID: 258500
  Orphanet ID: 300751
  SNOMED CT ID: 53043001

Molecular Interaction Atlas (MIA) of This Disease

This Disease Is Related to 102 DTT Molecule(s)

Gene Name	DTT ID	Evidence Level	Mode of Inheritance	REF
ADRB2	TTG8ZWP	Limited	Biomarker	[1]
ATM	TTKBM7V	Limited	Biomarker	[2]
CSF3	TT5TQ2W	Limited	Therapeutic	[3]
FASLG	TTO7014	Limited	Biomarker	[4]
GPX1	TTYAHBP	Limited	Biomarker	[5]
NPPB	TTY63XT	Limited	Altered Expression	[6]
NR3C2	TT26PHO	Limited	Biomarker	[7]
RAC1	TT2M9CG	Limited	Biomarker	[8]
SIK1	TT1H6LC	Limited	Biomarker	[9]
TCF7L2	TT80QAL	Limited	Biomarker	[10]
ABCC9	TTEF5MJ	Strong	Genetic Variation	[11]
ADAM33	TTQICM2	Strong	Posttranslational Modification	[12]
ADRB1	TTR6W5O	Strong	Biomarker	[13]
ADRB3	TTMXGCW	Strong	Biomarker	[14]
APLN	TT87D3J	Strong	Biomarker	[15]
APLNR	TTJ8E43	Strong	Biomarker	[15]
ATP2A2	TTE6THL	Strong	Altered Expression	[16]
CACNA1C	TTZIFHC	Strong	Altered Expression	[17]
CAPN2	TTG5QB7	Strong	Altered Expression	[18]
CD36	TTPJMCU	Strong	Altered Expression	[19]
CD59	TTBGTEJ	Strong	Genetic Variation	[20]
CDH5	TTXLCFO	Strong	Biomarker	[21]
CHRM2	TTYEG6Q	Strong	Genetic Variation	[22]
CTH	TTLQUZS	Strong	Biomarker	[23]
CTSC	TT4H0V2	Strong	Altered Expression	[24]
CYP11B2	TT9MNE2	Strong	Genetic Variation	[25]
DNAJB1	TTPXAWS	Strong	Biomarker	[26]
DUSP5	TTZN92A	Strong	Altered Expression	[27]
ECE1	TTQ9RYT	Strong	Biomarker	[28]
EIF2AK4	TT9U4EP	Strong	Biomarker	[29]
ESRRB	TTKF0XS	Strong	Biomarker	[30]
FABP3	TT3TGLR	Strong	Biomarker	[31]
FAS	TT7LTUJ	Strong	Genetic Variation	[32]
FASN	TT7AOUD	Strong	Biomarker	[33]
FGF21	TTQ916P	Strong	Biomarker	[34]
FUT3	TTUPAD7	Strong	Genetic Variation	[35]
GAPDH	TTUGSWA	Strong	Biomarker	[36]
GATA4	TT1VDN2	Strong	Altered Expression	[37]
GCLM	TTNFESW	Strong	Genetic Variation	[38]
GNAO1	TTAXD8Z	Strong	Biomarker	[39]
GRK2	TTAZ3MN	Strong	Altered Expression	[40]
HDAC11	TT8K17W	Strong	Altered Expression	[41]
HDAC3	TT4YWTO	Strong	Biomarker	[27]
HLA-DQB2	TTL7VOU	Strong	Biomarker	[39]
HRC	TTR4FKD	Strong	Genetic Variation	[42]
HSD17B2	TT0PT1R	Strong	Biomarker	[43]
IL1RL1	TT4GZA4	Strong	Biomarker	[44]
IL31	TT1RJXK	Strong	Altered Expression	[45]
ITGB1	TTBVIQC	Strong	Biomarker	[46]
KCNJ5	TTEO25X	Strong	Altered Expression	[47]
KDM2A	TT8XTY2	Strong	Altered Expression	[48]
LAMP2	TTULDG7	Strong	Genetic Variation	[49]
LHCGR	TT2O4W9	Strong	Biomarker	[50]
LIPE	TTLUQ8E	Strong	Altered Expression	[51]
LRRC32	TT0FAYT	Strong	Biomarker	[52]
LY75	TTG180Q	Strong	Biomarker	[53]
MGAM	TTXWASR	Strong	Genetic Variation	[54]
MGAT1	TTYJRN5	Strong	Genetic Variation	[55]
MKNK1	TTEZAUX	Strong	Biomarker	[56]
MYBPC3	TT9WOBN	Strong	Genetic Variation	[57]
MYH7	TTNIMDP	Strong	Genetic Variation	[58]
NCOA4	TT8OY02	Strong	Altered Expression	[59]
NEK2	TT3VZ24	Strong	Altered Expression	[60]
NODAL	TTK2O1Q	Strong	Altered Expression	[56]
NPR2	TTNB7IF	Strong	Genetic Variation	[61]
NR1H3	TTECBXN	Strong	Biomarker	[62]
PCCA	TT1JDE3	Strong	Biomarker	[63]
PCCB	TT5LURU	Strong	Genetic Variation	[64]
PDE1C	TTW2HRK	Strong	Biomarker	[65]
PDE2A	TTJGW1Z	Strong	Altered Expression	[66]
PDE3A	TT06AWU	Strong	Biomarker	[67]
PECAM1	TT4EZB2	Strong	Altered Expression	[68]
PLA2G7	TTDNFMT	Strong	Genetic Variation	[69]
PLIN1	TTIV27N	Strong	Biomarker	[51]
PPARGC1B	TTKSQ3W	Strong	Biomarker	[70]
PPP2CA	TTHTKNY	Strong	Biomarker	[71]
PRKCE	TT57MT2	Strong	Biomarker	[72]
PRKD1	TTSLUMT	Strong	Genetic Variation	[73]
PRKG1	TT7IZSA	Strong	Biomarker	[74]
PRSS12	TT2JYUE	Strong	Biomarker	[75]
PSEN1	TTZ3S8C	Strong	Genetic Variation	[76]
PSEN2	TTWN3F4	Strong	Genetic Variation	[77]
RAF1	TTAN5W2	Strong	Biomarker	[78]
RENBP	TTZCG0Q	Strong	Biomarker	[79]
RRM2	TT1S4LJ	Strong	Genetic Variation	[80]
SCN5A	TTZOVE0	Strong	Biomarker	[81]
SLC25A4	TTU5A6Q	Strong	Biomarker	[82]
SLC2A4	TTP6MT5	Strong	Biomarker	[83]
SLC5A1	TT2UE56	Strong	Biomarker	[84]
SMC2	TTS8D17	Strong	Biomarker	[85]
SPRY1	TT0PSN6	Strong	Altered Expression	[86]
SRGN	TTCHB06	Strong	Biomarker	[87]
SULF2	TTLQTHB	Strong	Biomarker	[88]
SYK	TT2HUPM	Strong	Biomarker	[89]
TIE1	TTT4236	Strong	Posttranslational Modification	[90]
TNNC1	TT8RDXP	Strong	Genetic Variation	[91]
TNNI3	TTNLDK6	Strong	Genetic Variation	[92]
TPH2	TT3KLDP	Strong	Genetic Variation	[93]
TRIM27	TTTO3QN	Strong	Genetic Variation	[94]
UCP1	TTI12YJ	Strong	Biomarker	[33]
ACE2	TTUI5H7	Definitive	Biomarker	[95]
SIRT3	TTVZLIJ	Definitive	Altered Expression	[96]

This Disease Is Related to 6 DTP Molecule(s)

Gene Name	DTP ID	Evidence Level	Mode of Inheritance	REF
CACNB2	DTBZWL4	Strong	Altered Expression	[47]
CACNB4	DTV8E46	Strong	Genetic Variation	[54]
SLC22A5	DT3HUVD	Strong	Biomarker	[63]
SLC25A5	DTL1TRY	Strong	Altered Expression	[82]
SLC25A6	DTLMGFJ	Strong	Biomarker	[82]
SLC35B2	DT81RKJ	Strong	Altered Expression	[97]

This Disease Is Related to 4 DME Molecule(s)

Gene Name	DME ID	Evidence Level	Mode of Inheritance	REF
DDAH1	DEY0TQC	Strong	Biomarker	[98]
PGM1	DEA3VM1	Strong	Biomarker	[99]
PNPO	DE3Z1RA	Strong	Biomarker	[100]
SULT1E1	DESTKG6	Strong	Biomarker	[101]

This Disease Is Related to 212 DOT Molecule(s)

Gene Name	DOT ID	Evidence Level	Mode of Inheritance	REF
ABRA	OTBQ2C1J	Limited	Biomarker	[9]
ALMS1	OTW66JKS	Limited	Biomarker	[102]
AXIN2	OTRMGQNU	Limited	Biomarker	[10]
CSRNP1	OTDK1FPH	Limited	Biomarker	[9]
GBE1	OTK2N05B	Limited	Biomarker	[63]
HAND2	OTCXYW4Y	Limited	Biomarker	[37]
SHBG	OTPWU5IW	Limited	Biomarker	[103]
HFE	OTDD93KB	moderate	Biomarker	[63]
MMACHC	OTX0TT3W	moderate	Biomarker	[63]
ACTA2	OTEDLG8E	Strong	Genetic Variation	[104]
ACTC1	OTJU04B1	Strong	Genetic Variation	[105]
ACTN2	OT9FOLD7	Strong	Biomarker	[106]
ACVR1C	OTOTYERF	Strong	Altered Expression	[107]
ADAMTS18	OTRMFI04	Strong	Biomarker	[108]
ADAMTS20	OTU0EKLN	Strong	Biomarker	[108]
ADAMTS8	OT2KFY1S	Strong	Altered Expression	[108]
AGR3	OTONJPDP	Strong	Biomarker	[109]
ALDH7A1	OTV57BZD	Strong	Biomarker	[66]
AMPD1	OTU17BCI	Strong	Genetic Variation	[110]
ANKRD1	OTHJ7JV9	Strong	Genetic Variation	[111]
ARHGEF5	OTUVGFT9	Strong	Genetic Variation	[112]
ASXL2	OTNG4E2M	Strong	Altered Expression	[113]
ATF1	OT251CI0	Strong	Altered Expression	[114]
ATP2A1	OT959A3A	Strong	Biomarker	[115]
ATP6AP2	OT0IABVV	Strong	Altered Expression	[116]
BAG3	OTVXYUDQ	Strong	Biomarker	[117]
BCL9	OTRBIPR4	Strong	Biomarker	[118]
BDH1	OT62RL5P	Strong	Biomarker	[119]
BGLAP	OTK1YLWQ	Strong	Biomarker	[120]
BTNL2	OTTTEMZA	Strong	Genetic Variation	[121]
BTNL9	OT3PWOH6	Strong	Biomarker	[122]
C4orf3	OT6TFN1O	Strong	Genetic Variation	[123]
CA8	OT9Y8GA8	Strong	Genetic Variation	[124]
CACYBP	OTJMZD2T	Strong	Altered Expression	[125]
CAP2	OTC1WFNO	Strong	Biomarker	[126]
CASZ1	OTWJ2OR8	Strong	Genetic Variation	[127]
CAV3	OTWSFDB4	Strong	Genetic Variation	[128]
CCNB2	OTIEXTDK	Strong	Genetic Variation	[80]
CELF1	OT6JQ5RS	Strong	Altered Expression	[129]
CFL2	OTE2W0DH	Strong	Posttranslational Modification	[130]
CHCHD2	OTL5PA3Y	Strong	Biomarker	[131]
CHPT1	OT4FJ0K3	Strong	Altered Expression	[132]
CLDN5	OTUX60YO	Strong	Biomarker	[122]
CLIC2	OTDBURM4	Strong	Altered Expression	[47]
CNN1	OTVPG39Z	Strong	Biomarker	[133]
COL5A1	OT24078H	Strong	Biomarker	[134]
COL5A2	OT5VOSQE	Strong	Altered Expression	[135]
CORIN	OT4SK7DK	Strong	Altered Expression	[6]
COX4I1	OTU0FC24	Strong	Altered Expression	[136]
COX4I2	OTB98B21	Strong	Altered Expression	[136]
CPT1A	OTI862QH	Strong	Altered Expression	[132]
CPT2	OTIN6G20	Strong	Altered Expression	[132]
CSH1	OT33HTRR	Strong	Biomarker	[137]
CSH2	OTW8JVAN	Strong	Biomarker	[137]
CSRP3	OTECBJMV	Strong	Genetic Variation	[138]
CST6	OTZVHJTF	Strong	Altered Expression	[139]
CTNNA3	OT9Z0P1E	Strong	Biomarker	[140]
CTRL	OTB6NA5O	Strong	Biomarker	[141]
DBT	OT4KZ5R9	Strong	Biomarker	[142]
DDAH2	OT8Q40G2	Strong	Biomarker	[98]
DDX53	OTHK3EGZ	Strong	Genetic Variation	[143]
DGCR8	OT62LXE4	Strong	Altered Expression	[144]
DLG1	OTCRZYWT	Strong	Biomarker	[145]
DNAH8	OTGES2OU	Strong	Altered Expression	[146]
DNAJA3	OT61924T	Strong	Biomarker	[147]
DNAJC19	OTLA1V91	Strong	Biomarker	[148]
DNTT	OTFSEF12	Strong	Biomarker	[149]
DOLK	OT2HTIAN	Strong	Genetic Variation	[150]
DROSHA	OTCE68KZ	Strong	Genetic Variation	[151]
DSG2	OTJPB2TO	Strong	Biomarker	[152]
DSP	OTB2MOP8	Strong	Genetic Variation	[153]
DUSP12	OT8WB1YB	Strong	Biomarker	[154]
E2F6	OT2PN28R	Strong	Biomarker	[119]
ECI1	OTRQTK84	Strong	Biomarker	[155]
EFEMP2	OT0I2B4J	Strong	Altered Expression	[156]
ELP1	OTYEWBF7	Strong	Biomarker	[157]
EMD	OTR8ZANE	Strong	Genetic Variation	[158]
EOMES	OTB9VQFA	Strong	Biomarker	[159]
ERBIN	OTNWTUA8	Strong	Genetic Variation	[160]
ERCC8	OT0T4WKI	Strong	Biomarker	[137]
ESYT1	OTA8NSJF	Strong	Genetic Variation	[161]
EYA4	OTINGR3Z	Strong	Genetic Variation	[162]
FANCC	OTTIDM3P	Strong	Genetic Variation	[163]
FBXO32	OTUE978R	Strong	Genetic Variation	[164]
FHOD3	OT1WUBQX	Strong	Genetic Variation	[165]
FKRP	OTMUZ7GH	Strong	Biomarker	[17]
FKTN	OTQ9GCXL	Strong	Genetic Variation	[166]
FOXG1	OTAW57J4	Strong	Genetic Variation	[75]
FRZB	OTTO3DPY	Strong	Altered Expression	[167]
FSD1	OT8P6PT3	Strong	Biomarker	[62]
FSD1L	OTBQ48RF	Strong	Biomarker	[62]
FXR1	OTEMQ1SR	Strong	Altered Expression	[168]
FYB1	OT6345CH	Strong	Biomarker	[169]
GAB1	OTQKE6V4	Strong	Biomarker	[170]
GABPA	OT9YB2SA	Strong	Altered Expression	[171]
GATA5	OTO81B63	Strong	Genetic Variation	[172]
GATAD1	OT0UZ3EP	Strong	Biomarker	[173]
HAND1	OTN4IPVV	Strong	Genetic Variation	[37]
HHEX	OTLIUVYX	Strong	Biomarker	[114]
HIVEP1	OT7CAG4A	Strong	Altered Expression	[156]
HLA-DPA1	OT7OG7Y2	Strong	Genetic Variation	[174]
HOPX	OTBSR6C9	Strong	Altered Expression	[175]
HSPB6	OTFPLGZI	Strong	Genetic Variation	[176]
INSIG2	OTX4VY51	Strong	Altered Expression	[177]
ISL1	OTVNVKAX	Strong	Biomarker	[178]
ITGB1BP2	OTHYX9F3	Strong	Genetic Variation	[179]
JARID2	OT14UM8H	Strong	Biomarker	[180]
JPH2	OTL9YH7V	Strong	Genetic Variation	[181]
KCNJ12	OTYN1E1R	Strong	Genetic Variation	[182]
KCNJ8	OTZ8G8FE	Strong	Altered Expression	[47]
KDM2B	OTDMCVW7	Strong	Biomarker	[183]
KMT2B	OTMMAZQX	Strong	Biomarker	[184]
KMT2C	OTC59BCO	Strong	Altered Expression	[185]
LDB3	OTGQL1AM	Strong	Genetic Variation	[186]
LMNB1	OT100T3P	Strong	Biomarker	[187]
LMO7	OTDLY6TC	Strong	Biomarker	[188]
LMOD2	OTFXHQFL	Strong	Genetic Variation	[189]
LRRC10	OT9V0ZBY	Strong	Genetic Variation	[190]
LTBP2	OTS88GSD	Strong	Altered Expression	[191]
LTBP4	OTC8WL2V	Strong	Genetic Variation	[192]
MAK16	OTD546E5	Strong	Genetic Variation	[193]
MDH1	OTJEO4E8	Strong	Altered Expression	[194]
MEF2A	OTV2SF6E	Strong	Biomarker	[195]
MEF2C	OTZGF1Y5	Strong	Genetic Variation	[196]
MINDY3	OT6YZPWC	Strong	Genetic Variation	[124]
MLKL	OTDSLC81	Strong	Biomarker	[197]
MMUT	OTBBBV70	Strong	Biomarker	[63]
MPI	OTBH6ZK1	Strong	Biomarker	[198]
MT3	OTVCZ7HI	Strong	Biomarker	[199]
MYBPC2	OTCXSB6A	Strong	Biomarker	[200]
MYH6	OT3YNCH1	Strong	Biomarker	[201]
MYL12B	OTXMLQOT	Strong	Genetic Variation	[202]
MYL3	OTKD3RSX	Strong	Genetic Variation	[203]
MYLK3	OTC58V2Q	Strong	Genetic Variation	[204]
MYOCD	OTSJNHTH	Strong	Altered Expression	[205]
MYOM3	OT8GGH11	Strong	Genetic Variation	[206]
MYOZ1	OT2XU9EU	Strong	Biomarker	[207]
MYOZ2	OTMEIQJA	Strong	Biomarker	[208]
NCOA6	OTOMIGTV	Strong	Biomarker	[209]
NEBL	OT2WH1NC	Strong	Genetic Variation	[210]
NIF3L1	OT4MP90J	Strong	Altered Expression	[36]
NKX2-5	OTS1SAWM	Strong	Biomarker	[211]
NOP53	OTA2YKO6	Strong	Altered Expression	[212]
NPPA	OTMQNTNX	Strong	Biomarker	[154]
NPTXR	OTQJEOIH	Strong	Genetic Variation	[61]
NUDT2	OTMHM1DH	Strong	Biomarker	[213]
NUS1	OT4DQ82L	Strong	Biomarker	[214]
OBSCN	OTT14OVX	Strong	Biomarker	[215]
PA2G4	OT7IG7HT	Strong	Biomarker	[216]
PCDH17	OTRK0M05	Strong	Altered Expression	[217]
PDLIM3	OTVXQC81	Strong	Biomarker	[218]
PIPOX	OTWTCOTN	Strong	Altered Expression	[219]
PIWIL1	OT7CRGZ3	Strong	Altered Expression	[220]
PIWIL2	OT1PXQIF	Strong	Altered Expression	[220]
PKP2	OTJOVF68	Strong	Genetic Variation	[221]
PLEKHM2	OT4ZYV73	Strong	Genetic Variation	[222]
PLIN2	OTRXJ9UN	Strong	Biomarker	[223]
PPM1K	OTNZ4N4E	Strong	Altered Expression	[224]
PPP1R13L	OTNCPLWE	Strong	Biomarker	[225]
PPP1R1A	OTGTAGCV	Strong	Altered Expression	[226]
PRDM16	OT0BGA27	Strong	Genetic Variation	[227]
PRG2	OT0BCPQG	Strong	Altered Expression	[156]
PRPF6	OT3U0ABN	Strong	Altered Expression	[82]
PXN	OTVMMUOF	Strong	Altered Expression	[228]
RB1CC1	OTZK8PFX	Strong	Altered Expression	[229]
RBM24	OTQI1AR1	Strong	Biomarker	[230]
RBM39	OTCMPTF9	Strong	Altered Expression	[116]
RGCC	OTYJMLWM	Strong	Altered Expression	[231]
RHOJ	OTWI65OA	Strong	Biomarker	[232]
RHOU	OTERIAD4	Strong	Altered Expression	[232]
RLN3	OTQSQMUQ	Strong	Biomarker	[233]
RYR2	OT0PF19E	Strong	Genetic Variation	[234]
S100A2	OTTGHJ1H	Strong	Altered Expression	[235]
SCARA3	OT46I38Y	Strong	Biomarker	[137]
SCN2B	OTFAHJ38	Strong	Altered Expression	[47]
SDC4	OTKUVUGZ	Strong	Biomarker	[236]
SDHA	OTOJ8QFF	Strong	Genetic Variation	[237]
SDHB	OTRE1M1T	Strong	Altered Expression	[238]
SERPINA12	OTS1E6IP	Strong	Biomarker	[239]
SOX18	OTPUMHWA	Strong	Altered Expression	[240]
SOX7	OTOZOFAG	Strong	Altered Expression	[240]
ST3GAL4	OTNENJZQ	Strong	Biomarker	[241]
STAP2	OTEB1VVI	Strong	Biomarker	[242]
SUGP1	OT7W0EB8	Strong	Biomarker	[243]
SYNE1	OTSBSLUH	Strong	Genetic Variation	[244]
TBX5	OT70PISV	Strong	Altered Expression	[245]
TCAP	OTQQMJ94	Strong	Genetic Variation	[246]
TEAD1	OTK6971C	Strong	Altered Expression	[247]
TIMELESS	OTD8DCBJ	Strong	Genetic Variation	[112]
TIMM23	OTAAS85T	Strong	Biomarker	[148]
TK2	OTS1V4XB	Strong	Altered Expression	[248]
TM7SF2	OTILU5S7	Strong	Biomarker	[90]
TMEM150A	OTHQ86N2	Strong	Genetic Variation	[249]
TMOD1	OTTRYF9Y	Strong	Genetic Variation	[250]
TMPO	OTL68EL4	Strong	Genetic Variation	[251]
TMPRSS13	OTMAOAP3	Strong	Biomarker	[252]
TNFAIP8	OT1G9297	Strong	Biomarker	[253]
TOR2A	OT1EGCDU	Strong	Biomarker	[254]
TPM1	OTD73X6R	Strong	Genetic Variation	[255]
TRIB3	OTG5OS7X	Strong	Altered Expression	[256]
TSHZ1	OTYQ9ECW	Strong	Genetic Variation	[257]
FLNC	OT3F8J6Y	Definitive	Genetic Variation	[153]
HLA-DQB1	OTVVI3UI	Definitive	Genetic Variation	[258]
LMNA	OT3SG7ZR	Definitive	Autosomal dominant	[259]
MARCKSL1	OT13J2FM	Definitive	Genetic Variation	[138]
MST1	OTOC4UNG	Definitive	Biomarker	[260]
MUC2	OT3X4QVX	Definitive	Genetic Variation	[138]
MYPN	OTHTOFDU	Definitive	Genetic Variation	[203]
RBM45	OTWTHD77	Definitive	Biomarker	[261]
SRF	OTW18FQN	Definitive	Biomarker	[126]
TBX20	OTMPU2XQ	Definitive	Genetic Variation	[178]
TIMP1	OTOXC51H	Definitive	Biomarker	[262]

References

• [1] Myocardial gene expression in dilated cardiomyopathy treated with beta-blocking agents.N Engl J Med. 2002 May 2;346(18):1357-65. doi: 10.1056/NEJMoa012630.
• [2] Deficiency of ataxia telangiectasia mutated kinase modulates cardiac remodeling following myocardial infarction: involvement in fibrosis and apoptosis.PLoS One. 2013 Dec 16;8(12):e83513. doi: 10.1371/journal.pone.0083513. eCollection 2013.
• [3] Granulocyte colony-stimulating factor improves left ventricular function of doxorubicin-induced cardiomyopathy.Lab Invest. 2007 May;87(5):440-55. doi: 10.1038/labinvest.3700530. Epub 2007 Mar 5.
• [4] Myocardial Fas ligand expression increases susceptibility to AZT-induced cardiomyopathy.Cardiovasc Toxicol. 2007;7(4):255-63. doi: 10.1007/s12012-007-9004-9. Epub 2007 Oct 18.
• [5] Interaction of glutathione peroxidase-1 and selenium in endemic dilated cardiomyopathy.Clin Chim Acta. 2009 Jan;399(1-2):102-8. doi: 10.1016/j.cca.2008.09.025. Epub 2008 Oct 2.
• [6] Natriuretic Peptide Processing in Patients with and Without Left Ventricular Dysfunction.Int Heart J. 2019 Jan 25;60(1):115-120. doi: 10.1536/ihj.18-012. Epub 2018 Dec 5.
• [7] Ablation of mineralocorticoid receptors in myocytes but not in fibroblasts preserves cardiac function.Hypertension. 2011 Apr;57(4):746-54. doi: 10.1161/HYPERTENSIONAHA.110.163287. Epub 2011 Feb 14.
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