General Information of Disease (ID: DIS3PNU3)

Disease Name Influenza
Synonyms
influenza infection; orthomyxoviridae infectious disease; orthomyxoviridae disease or disorder; Influenza with other manifestations; orthomyxoviridae caused disease or disorder; flu; influenza with non-respiratory manifestation
Disease Class 1E30-1E32: Influenza
Definition
An acute viral infection of the respiratory tract, occurring in isolated cases, in epidemics, or in pandemics; it is caused by serologically different strains of viruses (influenzaviruses) designated A, B, and C, has a 3-day incubation period, and usually lasts for 3 to 10 days. It is marked by inflammation of the nasal mucosa, pharynx, and conjunctiva; headache; myalgia; often fever, chills, and prostration; and occasionally involvement of the myocardium or central nervous system.
Disease Hierarchy
DIS7KC5K: Viral respiratory tract infection
DISDI77C: Primary viral infectious disease
DISEM33Q: Infectious disease
DIS3PNU3: Influenza
ICD Code
ICD-11
ICD-11: 1E30-1E32
ICD-10
ICD-10: J10, J11
ICD-9
ICD-9: 487, 488
Expand ICD-9
487488
Disease Identifiers
MONDO ID
MONDO_0005812
MESH ID
D007251
UMLS CUI
C0021400
MedGen ID
9466
SNOMED CT ID
6142004

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Fluzone QIV DML6IDH Approved NA [1]
Oseltamivir DMGO72P Approved Small molecular drug [2]
Zanamivir DMFMBZ4 Approved Small molecular drug [3]
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This Disease is Treated as An Indication in 15 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
mRNA-1010 DM07L0Y Phase 3 Vaccine [4]
VaxiGrip QIV IM DMD620F Phase 3 NA [5]
JNJ-0953 DMQ6513 Phase 2 NA [6]
mRNA-1020 DM2DIYJ Phase 2 Vaccine [7]
mRNA-1030 DMC1H46 Phase 2 Vaccine [7]
VXA-A1.1-H1 DM2Z8YM Phase 2 Vaccine [8]
GSK4382276A DMUSK1C Phase 1 MRNA vaccine [9]
KBP-V001 DMNBU67 Phase 1 Vaccine [10]
MER4101 DMNISCH Phase 1 Vaccine [11]
mRNA-1045 DMRDEPN Phase 1 Vaccine [12]
mRNA-1230 DM0RBQ5 Phase 1 Vaccine [12]
PF-07252220 DMLGWFN Phase 1 Vaccine [13]
PF-07845104 DM6N1VD Phase 1 Vaccine [14]
PF-07926307 DMJLZQB Phase 1 Vaccine [14]
SP0273 DMQK6RP Phase 1 Vaccine [15]
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⏷ Show the Full List of 15 Drug(s)
This Disease is Treated as An Indication in 1 Preclinical Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
mRNA-1012 DMD1LTB Preclinical Vaccine [16]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 129 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
BACE2 TT69DB8 Limited Biomarker [17]
CCL2 TTNAY0P Limited Biomarker [18]
IL31RA TT9HPX0 Limited Biomarker [19]
C5 TTKANGO moderate Biomarker [20]
CLCN7 TTST1AJ moderate Altered Expression [21]
CLEC9A TTGUSRB moderate Biomarker [22]
CLK1 TTE6YDG moderate Biomarker [23]
DNM1 TTE3JW9 moderate Biomarker [24]
DOT1L TTSZ8T1 moderate Biomarker [25]
EBI3 TTJF68X moderate Biomarker [26]
ENAH TTY36UA moderate Genetic Variation [27]
GALNS TTT9YPO moderate Genetic Variation [28]
GAST TT4LRVO moderate Genetic Variation [28]
ICOS TTE5VP6 moderate Biomarker [29]
IFNAR2 TTMQB37 moderate Biomarker [30]
IFNB1 TT4TZ8J moderate Biomarker [31]
IL17F TT2B6PS moderate Biomarker [32]
IL22 TTLDX4N moderate Biomarker [33]
IL32 TTD4G7L moderate Biomarker [34]
ITGAE TTH0Z37 moderate Biomarker [35]
KLK5 TTULSEW moderate Biomarker [36]
LAMP1 TTC214J moderate Biomarker [37]
LNPEP TTY2KP7 moderate Biomarker [38]
MBTPS1 TTNSM2I moderate Biomarker [39]
MLANA TT362RB moderate Biomarker [40]
MUC15 TTGQ6MI moderate Biomarker [41]
MUC5AC TTEL90S moderate Biomarker [42]
NR4A3 TTJQB49 moderate Biomarker [43]
PAM TTF4ZPC moderate Biomarker [44]
PPIA TTL2ADK moderate Biomarker [45]
SFTPD TTGLMU7 moderate Biomarker [46]
SHCBP1 TTZ9WGL moderate Biomarker [44]
SUGT1 TT7Q9WR moderate Altered Expression [47]
TIRAP TTKU0LS moderate Biomarker [48]
TLR8 TT8CWFK moderate Biomarker [49]
TMBIM6 TT7QSMG moderate Biomarker [50]
TNFRSF18 TTG6LA7 moderate Biomarker [51]
TNFSF13B TTWMIDN moderate Biomarker [52]
TRIM28 TTQ2BKV moderate Biomarker [53]
ACE2 TTUI5H7 Strong Biomarker [54]
ATF3 TTCE793 Strong Biomarker [55]
BACE1 TTJUNZF Strong Biomarker [56]
BST2 TT90BJT Strong Biomarker [57]
CASP1 TTCQIBE Strong Biomarker [58]
CASP10 TTX5HEK Strong Biomarker [59]
CCR2 TTFZYTO Strong Biomarker [60]
CCR5 TTJIH8Q Strong Biomarker [61]
CD1A TTBGTFN Strong Biomarker [62]
CD2 TTJDUNO Strong Biomarker [63]
CD248 TTYJWT7 Strong Genetic Variation [64]
CD28 TTQ13FT Strong Biomarker [65]
CD40LG TTIJP3Q Strong Altered Expression [66]
CD86 TT53XHB Strong Biomarker [67]
CES1 TTMF541 Strong Biomarker [68]
CR2 TT0HUN7 Strong Biomarker [69]
CSF3R TTC70AJ Strong Biomarker [70]
CXCL10 TTQOVYA Strong Biomarker [71]
DDIT4 TTVEOY6 Strong Altered Expression [72]
DDX5 TTZKPVC Strong Biomarker [73]
DDX58 TTVB0O3 Strong Biomarker [74]
DHFR TTYZVDJ Strong Biomarker [75]
DPEP1 TTYUENF Strong Biomarker [76]
EPHA3 TTHS2LR Strong Biomarker [77]
FOLH1 TT9G4N0 Strong Biomarker [78]
FPR2 TTOJ1NF Strong Biomarker [79]
FURIN TTH9WF6 Strong Biomarker [80]
GLA TTIS03D Strong Biomarker [81]
GLRX TTRJCNG Strong Biomarker [82]
GPI TT19JIZ Strong Biomarker [83]
GRN TT0LWE3 Strong Biomarker [84]
GZMB TTKEPHX Strong Biomarker [85]
HCRT TTU5HJP Strong Biomarker [86]
HLA-A TTHONFT Strong Biomarker [87]
HPD TT8DSFC Strong Biomarker [88]
IFNAR1 TTSYFMA Strong Biomarker [89]
IFNL1 TTM624L Strong Biomarker [90]
IL17D TTC5LTG Strong Biomarker [91]
IL1RL2 TTUS18T Strong Biomarker [92]
IL33 TT5MD4P Strong Biomarker [93]
IL7R TTAWI51 Strong Altered Expression [94]
IRAK3 TTBPJOK Strong Biomarker [95]
IRF3 TTYR7OH Strong Biomarker [96]
ISG15 TTVOH3T Strong Biomarker [97]
ITGB7 TTLT9XQ Strong Altered Expression [98]
KIR2DL1 TT4UXPE Strong Biomarker [99]
KLRG1 TT299E6 Strong Biomarker [100]
LANCL2 TTMK3EX Strong Biomarker [101]
MAPKAPK2 TTMUG9D Strong Biomarker [102]
MBL2 TTMQDZ5 Strong Genetic Variation [103]
MPL TTIHYA4 Strong Biomarker [104]
MRC1 TTKV8W5 Strong Biomarker [105]
MSR1 TT2TDH9 Strong Biomarker [106]
MYD88 TTB6Q2O Strong Biomarker [107]
NCR1 TTQNRJM Strong Biomarker [108]
NLRC5 TTWZC78 Strong Biomarker [109]
NLRX1 TTKT026 Strong Biomarker [110]
NR1I2 TT7LCTF Strong Biomarker [111]
P2RX1 TTJW7B3 Strong Biomarker [112]
P2RX3 TT2THBD Strong Biomarker [112]
P2RX4 TT1NLOA Strong Biomarker [112]
PBRM1 TTH8ZRL Strong Biomarker [113]
PCSK7 TTD30LY Strong Biomarker [114]
PDE7A TT1BC3A Strong Biomarker [115]
PDPK1 TTYMGWX Strong Biomarker [72]
PEBP1 TT1BGU8 Strong Genetic Variation [116]
PLK4 TTGPNZQ Strong Altered Expression [117]
PRNP TTY5F9C Strong Biomarker [118]
PRSS8 TTT4N0Q Strong Biomarker [119]
PTAFR TTQL5VC Strong Altered Expression [120]
RAB7A TTF6WAQ Strong Altered Expression [121]
SERPING1 TTVQ6R9 Strong Biomarker [55]
SERPINH1 TTPSWQG Strong Biomarker [122]
SLC22A8 TTTQR47 Strong Biomarker [123]
SLC27A4 TT20AYF Strong Biomarker [124]
SLC46A1 TTY8Z2E Strong Biomarker [115]
ST14 TTPRO7W Strong Biomarker [125]
STAT1 TTN7R6K Strong Biomarker [126]
TICAM1 TT2GQT6 Strong Biomarker [127]
TLR2 TTY7ZHS Strong Biomarker [128]
TLR3 TTD24Y0 Strong Biomarker [129]
TLR5 TTCXP8J Strong Biomarker [130]
TLR7 TTRJ1K4 Strong Biomarker [131]
TLR9 TTSHG0T Strong Biomarker [132]
TMPRSS11D TTWHYC8 Strong Altered Expression [133]
TMPRSS2 TT1GM2Z Strong Biomarker [134]
TNFRSF9 TTPW9LJ Strong Biomarker [135]
TNFSF10 TTA5MS9 Strong Biomarker [136]
WAS TTE8T73 Strong Biomarker [137]
XPO1 TTCJUR4 Strong Biomarker [138]
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⏷ Show the Full List of 129 DTT(s)
This Disease Is Related to 4 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC35A1 DTVZIRG Limited Biomarker [139]
SLC20A1 DTMULXV moderate Altered Expression [140]
SLC9A6 DTN0JXW moderate Biomarker [141]
ABCA3 DT2T6VQ Strong Genetic Variation [142]
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This Disease Is Related to 15 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
LPO DEHX1DZ Limited Biomarker [143]
CMPK1 DEMPH4I moderate Biomarker [144]
GLDC DEIN8FB moderate Biomarker [145]
NT5C2 DE1DOKJ moderate Biomarker [146]
SPR DEJVDAT moderate Biomarker [147]
UCK2 DETN1O0 moderate Biomarker [144]
AKR1C4 DEAJN47 Strong Genetic Variation [148]
UGT1A10 DEL5N6Y Strong Genetic Variation [149]
UGT1A3 DEF2WXN Strong Genetic Variation [149]
UGT1A4 DELOY3P Strong Genetic Variation [149]
UGT1A5 DEPF954 Strong Genetic Variation [149]
UGT1A6 DESD26P Strong Genetic Variation [149]
UGT1A7 DEZO4N3 Strong Genetic Variation [149]
UGT1A8 DE2GB8N Strong Genetic Variation [149]
UGT1A9 DE85D2P Strong Genetic Variation [149]
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⏷ Show the Full List of 15 DME(s)
This Disease Is Related to 289 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
BTBD8 OT3A3RD7 Limited Biomarker [150]
GAL3ST1 OTSFFZRD Limited Biomarker [139]
NUDT11 OTFDXJA1 Limited Biomarker [17]
ABHD2 OTCRUOCS moderate Biomarker [151]
ADAR OTQNOHR8 moderate Biomarker [152]
ANP32A OTRHPFO2 moderate Biomarker [153]
BATF2 OT4XBZC9 moderate Biomarker [154]
BCAM OTHZOPSD moderate Biomarker [155]
BCAP31 OTKSACR4 moderate Altered Expression [156]
BET1 OTGX2557 moderate Biomarker [157]
BPIFA1 OTQFD2J5 moderate Altered Expression [158]
C6orf47 OTMKBNDD moderate Biomarker [159]
CD207 OTI9RUDN moderate Biomarker [160]
CFDP1 OTXY7J96 moderate Altered Expression [161]
CLEC10A OTD8HQT6 moderate Altered Expression [162]
CPT2 OTIN6G20 moderate Genetic Variation [163]
DDOST OT39PDMS moderate Biomarker [164]
DDX3X OTDO4TRX moderate Biomarker [165]
DDX41 OT6KEIHP moderate Biomarker [166]
DISC1 OT43AW4H moderate Genetic Variation [167]
DMRTA1 OTRZY9E9 moderate Biomarker [38]
DNALI1 OTTB3L8N moderate Altered Expression [156]
ECD OT3L3PCU moderate Altered Expression [47]
EIF4A2 OT08H03R moderate Biomarker [168]
EIF4G2 OTEO98CR moderate Altered Expression [161]
ESCO2 OTJEMAQU moderate Altered Expression [169]
FLT3LG OTU0YGC4 moderate Biomarker [170]
FLVCR1 OT9XCFOC moderate Biomarker [171]
FUT2 OTLXM6WI moderate Altered Expression [172]
GEMIN4 OTX7402E moderate Altered Expression [161]
GINS4 OTCVOO3S moderate Altered Expression [173]
GOLPH3 OTDLGYM3 moderate Altered Expression [174]
GOSR1 OTX8TMVU moderate Altered Expression [156]
GPS1 OT97FRYE moderate Biomarker [175]
H1-2 OT0AVI4M moderate Posttranslational Modification [176]
HACD1 OTEC7EP7 moderate Biomarker [38]
HOPX OTBSR6C9 moderate Altered Expression [21]
IL17C OTKXIVNQ moderate Biomarker [177]
IL18R1 OT83XMPQ moderate Biomarker [26]
IL22RA1 OTGVKLBR moderate Biomarker [178]
IL22RA2 OTGOFDCY moderate Biomarker [33]
ILF3 OTKMZ5K5 moderate Biomarker [179]
IPO5 OTAK40ED moderate Biomarker [180]
JTB OT314JB6 moderate Biomarker [181]
KEL OT47DJW0 moderate Biomarker [21]
KLRD1 OTMYLOV4 moderate Biomarker [182]
LRIT1 OTNEQPMZ moderate Biomarker [44]
LSAMP OTYXVQX2 moderate Biomarker [183]
MATN1 OTBRTCTQ moderate Biomarker [184]
MAX OTKZ0YKM moderate Biomarker [185]
MCF2L OTEURA8N moderate Biomarker [164]
MMUT OTBBBV70 moderate Genetic Variation [186]
MORC3 OT81NKVT moderate Biomarker [187]
MPPE1 OTINBJVE moderate Biomarker [188]
MTSS2 OTKMNSBF moderate Biomarker [189]
MUC5B OTPW6K5C moderate Altered Expression [190]
NCR2 OT2H13BX moderate Biomarker [191]
NMS OTFYS4LO moderate Genetic Variation [192]
NPL OTA7P0TO moderate Biomarker [193]
NUP93 OT4J2VAL moderate Biomarker [194]
PA2G4 OT7IG7HT moderate Biomarker [195]
PACC1 OTKBS8CC moderate Biomarker [196]
PAGR1 OTXR5PQ8 moderate Genetic Variation [28]
PDIA3 OTHPQ0Q3 moderate Biomarker [197]
PLAAT4 OTI66SAJ moderate Biomarker [198]
POLR2A OTHJQ1DZ moderate Biomarker [26]
POLR2B OTS3F0H2 moderate Genetic Variation [199]
POU1F1 OTXT8A5C moderate Biomarker [140]
PPP1R12A OT4AVU95 moderate Biomarker [200]
PRDM1 OTQLSVBS moderate Biomarker [201]
PSMD2 OT6HZHN7 moderate Altered Expression [161]
RAB39B OTDCLLT0 moderate Biomarker [202]
RIPK3 OTL1D484 moderate Biomarker [58]
ROBO3 OTPVG40S moderate Biomarker [74]
RTL1 OTOT33IM moderate Biomarker [40]
SARS1 OTFKXQ1O moderate Genetic Variation [203]
SARS2 OTU4T99W moderate Genetic Variation [203]
SEC14L2 OTJST64D moderate Biomarker [204]
SERPINB6 OT7G55IK moderate Biomarker [38]
SGTA OTKOJ3JB moderate Altered Expression [47]
SMS OT8JYKNH moderate Biomarker [205]
SMU1 OTLCSLGL moderate Biomarker [206]
SORBS1 OTWH8762 moderate Biomarker [38]
SPOCK2 OTXSVTSA moderate Biomarker [207]
STAT2 OTO9G2RZ moderate Biomarker [141]
STING1 OTDAP4G0 moderate Biomarker [166]
TECR OT2NT4MV moderate Biomarker [208]
TMED5 OT70W1J8 moderate Altered Expression [156]
TNFSF9 OTV9L89D moderate Biomarker [94]
TRAF3 OT5TQBGV moderate Biomarker [209]
TRIM14 OTLQKUG0 moderate Biomarker [210]
TRIM41 OTU3ADNG moderate Altered Expression [211]
ADAMTS7 OTVKZ1DV Strong Biomarker [212]
AGA OTNWT1WB Strong Biomarker [213]
ALYREF OTOF2ADD Strong Biomarker [214]
ANXA13 OTM33P73 Strong Genetic Variation [215]
AP2M1 OTQCOSFN Strong Biomarker [216]
APOL6 OTYTBJEG Strong Biomarker [55]
ARHGAP21 OT6XY8Y9 Strong Biomarker [217]
ARHGAP45 OTL86FEQ Strong Genetic Variation [218]
ARSF OTC0L12N Strong Biomarker [214]
ASZ1 OTLM93UO Strong Biomarker [219]
ATN1 OTNZFLKY Strong Biomarker [220]
ATP2C1 OTQN51T3 Strong Biomarker [221]
B3GAT1 OTXFP98E Strong Biomarker [222]
B3GNT3 OTVT1Q25 Strong Genetic Variation [223]
B4GALNT2 OT85V4QV Strong Altered Expression [224]
BAMBI OTCEJ8W5 Strong Altered Expression [225]
BCL6B OT1T5KM6 Strong Biomarker [226]
C4BPA OTHNH6Y8 Strong Biomarker [227]
C6 OTCKR304 Strong Altered Expression [228]
CALCOCO2 OTRGX0OV Strong Biomarker [229]
CAMK2B OTS9YK3E Strong Biomarker [230]
CAP1 OTYM8A2N Strong Biomarker [38]
CARD14 OTADQHOV Strong Biomarker [227]
CBLIF OTNE20WU Strong Genetic Variation [231]
CCL28 OTY6XNQ7 Strong Biomarker [232]
CCL4L2 OTDBSXOU Strong Altered Expression [233]
CCL8 OTCTWYN8 Strong Biomarker [55]
CCNT1 OTDYVGCP Strong Biomarker [234]
CD177 OTS79FNF Strong Biomarker [235]
CD48 OT83ZNPP Strong Biomarker [236]
CD81 OTQFXNAZ Strong Biomarker [237]
CDSN OTQW4HV6 Strong Biomarker [238]
CENPF OT7AG0SW Strong Biomarker [115]
CFAP97 OT0RSQO4 Strong Biomarker [239]
CHD6 OTEHW1U2 Strong Biomarker [240]
CHP1 OTHTXN1A Strong Biomarker [241]
CLDN2 OTRF3D6Y Strong Biomarker [242]
CLEC5A OT19WV30 Strong Biomarker [243]
CLEC7A OTRTBH27 Strong Altered Expression [244]
CNOT4 OTM8I5RH Strong Biomarker [245]
CPSF4 OT53UK5L Strong Biomarker [246]
CREM OTJIJ5AL Strong Biomarker [247]
CRLF3 OTT9TMXN Strong Biomarker [248]
CTHRC1 OTV88X2G Strong Altered Expression [249]
DDX39B OTEVCFVU Strong Biomarker [250]
DDX60 OTVPHA0C Strong Biomarker [55]
DEFA1 OT5N1B9B Strong Biomarker [251]
DEFB103B OT8RWY64 Strong Biomarker [252]
DHRS2 OTFHWIY8 Strong Biomarker [253]
DHX58 OT19BYB1 Strong Biomarker [254]
DHX9 OT5AAOQI Strong Biomarker [255]
DLAT OT9LBJVN Strong Genetic Variation [256]
DOCK3 OTF3YS2W Strong Genetic Variation [116]
DPF2 OTL0JH2C Strong Biomarker [257]
DYNC1LI1 OTJUR82A Strong Biomarker [258]
DYNC1LI2 OTR7WJES Strong Genetic Variation [259]
EGFLAM OTACZZJ0 Strong Biomarker [260]
EIF4A1 OTMTBX6N Strong Biomarker [168]
EIF4G1 OT2CF1E6 Strong Biomarker [261]
ERVW-1 OTWV8DXJ Strong Biomarker [262]
FCN2 OTTHJBKZ Strong Biomarker [263]
FRMD7 OTJ11849 Strong Biomarker [264]
FYB1 OT6345CH Strong Biomarker [265]
GATAD2B OTJL128N Strong Biomarker [73]
GBP1 OTUM7RPJ Strong Biomarker [55]
GRSF1 OTY6HNI7 Strong Biomarker [266]
GZMA OT43R33L Strong Altered Expression [267]
HEATR6 OTD3MYS0 Strong Biomarker [151]
HERC5 OTZ5PR39 Strong Biomarker [55]
HERC6 OT7G9PQE Strong Biomarker [55]
HLA-C OTV38BUJ Strong Biomarker [268]
IFI27 OTI2XGIT Strong Biomarker [55]
IFI35 OTV9RZ53 Strong Biomarker [55]
IFI44 OTOKSZVA Strong Biomarker [55]
IFI44L OTXKORJP Strong Biomarker [55]
IFI6 OTWOOAM4 Strong Biomarker [55]
IFIH1 OTZA2AHA Strong Biomarker [269]
IFIT1 OTXOQDSG Strong Biomarker [55]
IFIT2 OTI4EOAR Strong Biomarker [55]
IFIT3 OTPGHZB9 Strong Biomarker [55]
IFIT5 OTYTSO77 Strong Biomarker [270]
IFITM1 OTECO1G8 Strong Altered Expression [271]
IFITM3 OT2QP8D3 Strong Altered Expression [272]
IFNA6 OTX5EQ87 Strong Biomarker [273]
IFNGR1 OTCTQBWW Strong Biomarker [274]
IKBKE OT5VYOSM Strong Biomarker [275]
IL17RA OTVVI8ER Strong Altered Expression [276]
IL27 OTIS3OF8 Strong Altered Expression [156]
IRF7 OTC1A2PQ Strong Genetic Variation [277]
IRF9 OTK4MYQJ Strong Genetic Variation [96]
ISG20 OTCWRJJW Strong Altered Expression [66]
KLRB1 OTQ2959Y Strong Biomarker [278]
KLRC2 OTT4N86S Strong Genetic Variation [279]
KPNA1 OTEMVAJ6 Strong Biomarker [280]
KPNA3 OTLI3TM2 Strong Biomarker [213]
KPNA4 OTP0EX18 Strong Genetic Variation [280]
KRT10 OTSVRD3Q Strong Biomarker [281]
KRT31 OTB6RCAH Strong Biomarker [282]
KRT32 OTZCGZYT Strong Biomarker [283]
LAMP3 OTN0XL3W Strong Biomarker [183]
LY6E OTMG16BZ Strong Biomarker [55]
MAK16 OTD546E5 Strong Biomarker [266]
MAP2K6 OTK13JKC Strong Biomarker [284]
MAVS OTTQ0J64 Strong Biomarker [285]
MBD1 OTD19VO6 Strong Biomarker [76]
MCU OTQZAYWQ Strong Biomarker [286]
MED1 OTOO24C4 Strong Genetic Variation [116]
MX1 OT6X8G5T Strong Biomarker [287]
MX2 OT05NF37 Strong Biomarker [55]
MYO1G OTOCFS3Q Strong Biomarker [283]
MYOM2 OTD2UOXW Strong Biomarker [288]
NAGA OTNUEUZY Strong Altered Expression [289]
NDFIP1 OTIORSWF Strong Biomarker [290]
NFKBIB OTY1ZJXH Strong Altered Expression [291]
NFKBIL1 OTYFTPS0 Strong Biomarker [292]
NHS OTKE8QAT Strong Biomarker [293]
NLRC4 OTAIA3NA Strong Biomarker [294]
NRSN1 OT1KKXC8 Strong Biomarker [241]
OAS1 OT8ZLOCY Strong Altered Expression [295]
OAS2 OT64CCTM Strong Biomarker [97]
OAS3 OT6E5FYS Strong Biomarker [55]
OASL OTZ05YRP Strong Biomarker [55]
OTUD4 OT7U62SW Strong Biomarker [296]
P2RX2 OT0LF34A Strong Biomarker [112]
P2RX6 OT1FNTXA Strong Biomarker [112]
PABPN1 OT3MC5SE Strong Biomarker [297]
PARP12 OTCQTYIO Strong Biomarker [55]
PER2 OTU2B1DJ Strong Biomarker [298]
PITX1 OTA0UN4C Strong Altered Expression [299]
PKD1 OT5ALRZ5 Strong Genetic Variation [116]
PKP2 OTJOVF68 Strong Biomarker [300]
PLS1 OTWURB8U Strong Biomarker [301]
PLSCR1 OTGY9B5T Strong Altered Expression [302]
POLD3 OTEQEFQ2 Strong Biomarker [73]
POTEF OTV3WXYE Strong Genetic Variation [303]
PPBP OT1FHGQS Strong Genetic Variation [116]
PPIE OTIE5OAD Strong Biomarker [304]
PRDX2 OTLWCY9T Strong Biomarker [227]
PRM3 OT6574BF Strong Biomarker [305]
PRPF18 OTX4VZ4R Strong Biomarker [306]
PRPF8 OTU39JZI Strong Altered Expression [307]
PRSS57 OTR6GDQM Strong Biomarker [308]
PSMD4 OTH1VZTM Strong Biomarker [214]
PTF1A OT7SWA57 Strong Biomarker [248]
RAB11A OTC4FW0J Strong Biomarker [309]
RAB5A OTFR2KM4 Strong Altered Expression [121]
RAB7B OT60A0E9 Strong Altered Expression [121]
RIDA OTW4098I Strong Genetic Variation [310]
RNASE1 OTKZ7CO9 Strong Biomarker [311]
RNPC3 OTW5MKC1 Strong Biomarker [210]
RPS19 OTBKGP48 Strong Biomarker [312]
RSAD2 OTCA9WCM Strong Biomarker [97]
RTN3 OTGZ51QF Strong Genetic Variation [313]
RTP4 OTPHXVTY Strong Biomarker [55]
RUNX1T1 OT30DED5 Strong Genetic Variation [148]
SAFB OTGRV2LW Strong Genetic Variation [313]
SAG OTDNS3ZQ Strong Biomarker [248]
SAMD9 OTDG48P0 Strong Biomarker [55]
SARDH OTQ49Q27 Strong Biomarker [111]
SCGB3A1 OTIR98RB Strong Biomarker [296]
SCO2 OTJQQDRS Strong Biomarker [55]
SDS OT5WTJ2M Strong Biomarker [314]
SETDB1 OTWVUA1B Strong Altered Expression [299]
SFTPB OTOHS07E Strong Genetic Variation [315]
SGK3 OTQ6QO99 Strong Biomarker [316]
SH2D1A OTLU49I5 Strong Biomarker [317]
SH3GLB2 OTF7BB9S Strong Biomarker [318]
SIGLEC1 OTNWSQA9 Strong Biomarker [55]
SNRNP200 OTSAU864 Strong Biomarker [179]
SOCS5 OTN1ABYR Strong Altered Expression [319]
SON OT9VWV18 Strong Biomarker [320]
SPINT1 OT1CLR5L Strong Biomarker [321]
SRL OT7IEBWZ Strong Biomarker [111]
SRSF1 OTF61HOV Strong Biomarker [214]
SRSF2 OTVDHO6U Strong Biomarker [322]
SRSF3 OTOFT707 Strong Biomarker [214]
ST13 OTNML6UP Strong Biomarker [248]
ST3GAL3 OTOORKUE Strong Biomarker [323]
SUGP1 OT7W0EB8 Strong Biomarker [324]
TARS1 OT0PWST5 Strong Genetic Variation [325]
TARS2 OTXQY23P Strong Genetic Variation [325]
TARS3 OTPMDV66 Strong Genetic Variation [325]
TDRD7 OTK639ET Strong Biomarker [55]
TLR10 OTQ1KVJO Strong Biomarker [326]
TMED2 OTBLO7RW Strong Biomarker [241]
TNFAIP6 OT1SLUZH Strong Biomarker [55]
TNMD OTHLVA9G Strong Biomarker [327]
TOR1B OTNEL2PZ Strong Biomarker [55]
TPPP OTCFMSUF Strong Biomarker [241]
TRAM1 OT3I0H8E Strong Biomarker [328]
TREML4 OT2VLMTL Strong Biomarker [329]
TREX1 OTQG7K12 Strong Biomarker [55]
TRIM22 OTJBLG5R Strong Biomarker [55]
TRIM25 OT35SG1R Strong Genetic Variation [330]
TRIM3 OT704FQ0 Strong Biomarker [331]
TRIM56 OTFGU8E3 Strong Biomarker [43]
TRIM69 OTTEGTRD Strong Biomarker [127]
------------------------------------------------------------------------------------
⏷ Show the Full List of 289 DOT(s)

References

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29 Human V9V2-T Cells Synergize CD4(+) T Follicular Helper Cells to Produce Influenza Virus-Specific Antibody.Front Immunol. 2018 Apr 4;9:599. doi: 10.3389/fimmu.2018.00599. eCollection 2018.
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36 Kallikrein-related peptidase 5 and seasonal influenza viruses, limitations of the experimental models for activating proteases.Biol Chem. 2018 Sep 25;399(9):1053-1064. doi: 10.1515/hsz-2017-0340.
37 IL-15 Promotes Polyfunctional NK Cell Responses to Influenza by Boosting IL-12 Production.J Immunol. 2018 Apr 15;200(8):2738-2747. doi: 10.4049/jimmunol.1701614. Epub 2018 Feb 28.
38 DMO-CAP inhibits influenza virus replication by activating heme oxygenase-1-mediated IFN response.Virol J. 2019 Feb 20;16(1):21. doi: 10.1186/s12985-019-1125-9.
39 Dissecting influenza virus pathogenesis uncovers a novel chemical approach to combat the infection.Virology. 2013 Jan 5;435(1):92-101. doi: 10.1016/j.virol.2012.09.039.
40 Soluble human LAG-3 molecule amplifies the in vitro generation of type 1 tumor-specific immunity.Cancer Res. 2006 Apr 15;66(8):4450-60. doi: 10.1158/0008-5472.CAN-05-2728.
41 Upregulation of cell-surface mucin MUC15 in human nasal epithelial cells upon influenza A virus infection.BMC Infect Dis. 2019 Jul 15;19(1):622. doi: 10.1186/s12879-019-4213-y.
42 Overexpressing mouse model demonstrates the protective role of Muc5ac in the lungs.Proc Natl Acad Sci U S A. 2012 Oct 9;109(41):16528-33. doi: 10.1073/pnas.1206552109. Epub 2012 Sep 24.
43 The C-Terminal Tail of TRIM56 Dictates Antiviral Restriction of Influenza A and B Viruses by Impeding Viral RNA Synthesis.J Virol. 2016 Apr 14;90(9):4369-4382. doi: 10.1128/JVI.03172-15. Print 2016 May.
44 Be Aware of Immunogenic But not Protective Antigens: The Actinobacillus pleuropneumoniae PalA as an Example.Protein Pept Lett. 2017;24(11):1059-1065. doi: 10.2174/0929866524666170822121558.
45 Insights into the roles of cyclophilin A during influenza virus infection.Viruses. 2013 Jan 15;5(1):182-91. doi: 10.3390/v5010182.
46 Influenza Virus Hemagglutinins H2, H5, H6, and H11 Are Not Targets of Pulmonary Surfactant Protein D: N-Glycan Subtypes in Host-Pathogen Interactions.J Virol. 2020 Feb 14;94(5):e01951-19. doi: 10.1128/JVI.01951-19. Print 2020 Feb 14.
47 Optimized Expression, Purification, and Rapid Detection of Recombinant Influenza Nucleoproteins Expressed in Sf9 Insect Cells.J Microbiol Biotechnol. 2018 Oct 28;28(10):1683-1690. doi: 10.4014/jmb.1805.05053.
48 A Decoy Peptide that Disrupts TIRAP Recruitment to TLRs Is Protective in a Murine Model of Influenza.Cell Rep. 2015 Jun 30;11(12):1941-52. doi: 10.1016/j.celrep.2015.05.035. Epub 2015 Jun 18.
49 Generation of a KSCBi005-A-5(TLR8KO-A10) homozygous knockout human induced pluripotent stem cell line using CRISPR/Cas9.Stem Cell Res. 2019 Oct;40:101561. doi: 10.1016/j.scr.2019.101561. Epub 2019 Aug 27.
50 Bax Inhibitor-1 Acts as an Anti-Influenza Factor by Inhibiting ROS Mediated Cell Death and Augmenting Heme-Oxygenase 1 Expression in Influenza Virus Infected Cells.Int J Mol Sci. 2018 Mar 2;19(3):712. doi: 10.3390/ijms19030712.
51 Influenza-Activated ILC1s Contribute to Antiviral Immunity Partially Influenced by Differential GITR Expression.Front Immunol. 2018 Mar 22;9:505. doi: 10.3389/fimmu.2018.00505. eCollection 2018.
52 Highly immunogenic influenza virus-like particles containing B-cell-activating factor (BAFF) for multi-subtype vaccine development.Antiviral Res. 2019 Apr;164:12-22. doi: 10.1016/j.antiviral.2019.02.004. Epub 2019 Feb 6.
53 An influenza virus-triggered SUMO switch orchestrates co-opted endogenous retroviruses to stimulate host antiviral immunity.Proc Natl Acad Sci U S A. 2019 Aug 27;116(35):17399-17408. doi: 10.1073/pnas.1907031116. Epub 2019 Aug 7.
54 miRNA-200c-3p is crucial in acute respiratory distress syndrome.Cell Discov. 2017 Jun 27;3:17021. doi: 10.1038/celldisc.2017.21. eCollection 2017.
55 A host transcriptional signature for presymptomatic detection of infection in humans exposed to influenza H1N1 or H3N2.PLoS One. 2013;8(1):e52198. doi: 10.1371/journal.pone.0052198. Epub 2013 Jan 9.
56 Vaccination using recombinants influenza and adenoviruses encoding amastigote surface protein-2 are highly effective on protection against Trypanosoma cruzi infection.PLoS One. 2013 Apr 24;8(4):e61795. doi: 10.1371/journal.pone.0061795. Print 2013.
57 Limiting Respiratory Viral Infection by Targeting Antiviral and Immunological Functions of BST-2/Tetherin: Knowledge and Gaps.Bioessays. 2018 Oct;40(10):e1800086. doi: 10.1002/bies.201800086. Epub 2018 Aug 16.
58 RIP3 deficiency ameliorates inflammatory response in mice infected with influenza H7N9 virus infection.Oncotarget. 2017 Apr 25;8(17):27715-27724. doi: 10.18632/oncotarget.16016.
59 Differential responses to rhinovirus- and influenza-associated pulmonary exacerbations in patients with cystic fibrosis.Ann Am Thorac Soc. 2014 May;11(4):554-61. doi: 10.1513/AnnalsATS.201310-346OC.
60 Monocytes Represent One Source of Bacterial Shielding from Antibiotics following Influenza Virus Infection.J Immunol. 2019 Apr 1;202(7):2027-2034. doi: 10.4049/jimmunol.1801471. Epub 2019 Feb 11.
61 Influenza virus infection exacerbates experimental autoimmune encephalomyelitis disease by promoting type I T cells infiltration into central nervous system.J Autoimmun. 2017 Feb;77:1-10. doi: 10.1016/j.jaut.2016.10.006. Epub 2016 Oct 27.
62 RLR-mediated production of interferon- by a human dendritic cell subset and its role in virus-specific immunity.J Leukoc Biol. 2012 Jul;92(1):159-69. doi: 10.1189/jlb.0711360. Epub 2012 Apr 18.
63 Isolation, expression, and nucleotide sequencing of the pilin structural gene of the Brazilian purpuric fever clone of Haemophilus influenzae biogroup aegyptius.Infect Immun. 1993 May;61(5):2233-7. doi: 10.1128/iai.61.5.2233-2237.1993.
64 Antimicrobial susceptibility and genetic characteristics of Haemophilus influenzae isolated from community-acquired respiratory tract infection patients in Shanghai City, China.J Infect Chemother. 2012 Aug;18(4):508-14. doi: 10.1007/s10156-012-0372-0.
65 CD4+ CD31+ recent thymic emigrants in CHD7 haploinsufficiency (CHARGE syndrome): a case.Hum Immunol. 2013 Sep;74(9):1047-50. doi: 10.1016/j.humimm.2013.06.002. Epub 2013 Jun 7.
66 Identification of murine antigen-specific T follicular helper cells using an activation-induced marker assay.J Immunol Methods. 2019 Apr;467:48-57. doi: 10.1016/j.jim.2019.02.008. Epub 2019 Feb 22.
67 PD-1(hi) CD8(+) resident memory T cells balance immunity and fibrotic sequelae.Sci Immunol. 2019 Jun 14;4(36):eaaw1217. doi: 10.1126/sciimmunol.aaw1217.
68 The novel carboxylesterase 1 variant c.662A>G may decrease the bioactivation of oseltamivir in humans.PLoS One. 2017 Apr 24;12(4):e0176320. doi: 10.1371/journal.pone.0176320. eCollection 2017.
69 A new therapeutic strategy for lung tissue injury induced by influenza with CR2 targeting complement inhibitor.Virol J. 2010 Feb 9;7:30. doi: 10.1186/1743-422X-7-30.
70 Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis.J Immunol. 2016 Dec 1;197(11):4392-4402. doi: 10.4049/jimmunol.1600121. Epub 2016 Nov 2.
71 Rhinovirus respiratory tract infection in hospitalized adult patients is associated with T(H)2 response irrespective of asthma.J Infect. 2018 May;76(5):465-474. doi: 10.1016/j.jinf.2018.02.005. Epub 2018 Feb 15.
72 Influenza virus differentially activates mTORC1 and mTORC2 signaling to maximize late stage replication.PLoS Pathog. 2017 Sep 27;13(9):e1006635. doi: 10.1371/journal.ppat.1006635. eCollection 2017 Sep.
73 Purification and partial characterization of a cellular inhibitor of the interferon-induced protein kinase of Mr 68,000 from influenza virus-infected cells.Proc Natl Acad Sci U S A. 1990 Aug;87(16):6208-12. doi: 10.1073/pnas.87.16.6208.
74 Screening of Antiviral Components of Ma Huang Tang and Investigation on the Ephedra Alkaloids Efficacy on Influenza Virus Type A.Front Pharmacol. 2019 Sep 10;10:961. doi: 10.3389/fphar.2019.00961. eCollection 2019.
75 Synthesis, biological evaluation and molecular modeling of novel azaspiro dihydrotriazines as influenza virus inhibitors targeting the host factor dihydrofolate reductase (DHFR).Eur J Med Chem. 2018 Jul 15;155:229-243. doi: 10.1016/j.ejmech.2018.05.059. Epub 2018 Jun 2.
76 Expression of mouse beta-defensin-3 in MDCK cells and its anti-influenza-virus activity.Arch Virol. 2009;154(4):639-47. doi: 10.1007/s00705-009-0352-6. Epub 2009 Mar 20.
77 Characterization of influenza H1N1 Gag virus-like particles and extracellular vesicles co-produced in HEK-293SF.Vaccine. 2019 Nov 8;37(47):7100-7107. doi: 10.1016/j.vaccine.2019.07.057. Epub 2019 Jul 26.
78 Preclinical Evaluation of (203/212)Pb-Labeled Low-Molecular-Weight Compounds for Targeted Radiopharmaceutical Therapy of Prostate Cancer.J Nucl Med. 2020 Jan;61(1):80-88. doi: 10.2967/jnumed.119.229393. Epub 2019 Jun 28.
79 The Annexin A1 Receptor FPR2 Regulates the Endosomal Export of Influenza Virus.Int J Mol Sci. 2018 May 8;19(5):1400. doi: 10.3390/ijms19051400.
80 Evaluation of the hybrid resolution PACE model for the study of folding, insertion, and pore formation of membrane associated peptides.J Comput Chem. 2017 Jun 15;38(16):1462-1471. doi: 10.1002/jcc.24694. Epub 2017 Jan 19.
81 Lipid envelope-type nanoparticle incorporating a multifunctional peptide for systemic siRNA delivery to the pulmonary endothelium.ACS Nano. 2013 Sep 24;7(9):7534-41. doi: 10.1021/nn401317t. Epub 2013 Aug 21.
82 Expression of a peroxiredoxin-glutaredoxin by Haemophilus influenzae in biofilms and during human respiratory tract infection.FEMS Immunol Med Microbiol. 2005 Apr 1;44(1):81-9. doi: 10.1016/j.femsim.2004.12.008.
83 Influenza virus-like particles composed of conserved influenza proteins and GPI-anchored CCL28/GM-CSF fusion proteins enhance protective immunity against homologous and heterologous viruses.Int Immunopharmacol. 2018 Oct;63:119-128. doi: 10.1016/j.intimp.2018.07.011. Epub 2018 Aug 3.
84 Progranulin aggravates pulmonary immunopathology during influenza virus infection.Thorax. 2019 Mar;74(3):305-308. doi: 10.1136/thoraxjnl-2018-211916. Epub 2018 Sep 18.
85 Overarching Immunodominance Patterns and Substantial Diversity in Specificity and Functionality in the Circulating Human Influenza A and B Virus-Specific CD4+ T-Cell Repertoire.J Infect Dis. 2018 Aug 24;218(7):1169-1174. doi: 10.1093/infdis/jiy288.
86 History of narcolepsy at Stanford University.Immunol Res. 2014 May;58(2-3):315-39. doi: 10.1007/s12026-014-8513-4.
87 Variation at Extra-epitopic Amino Acid Residues Influences Suppression of Influenza Virus Replication by M1(58-66) Epitope-Specific CD8(+) T Lymphocytes.J Virol. 2018 May 14;92(11):e00232-18. doi: 10.1128/JVI.00232-18. Print 2018 Jun 1.
88 Sequence variation in the hpd gene of nonencapsulated Haemophilus influenzae isolated from patients with chronic bronchitis.Gene. 1997 May 20;191(1):57-60. doi: 10.1016/s0378-1119(97)00030-9.
89 Type I interferon induced by DNA of nontypeable Haemophilus influenza modulates inflammatory cytokine profile to promote susceptibility to this bacterium.Int Immunopharmacol. 2019 Sep;74:105710. doi: 10.1016/j.intimp.2019.105710. Epub 2019 Jun 27.
90 Innate Immune Response to Influenza Virus at Single-Cell Resolution in Human Epithelial Cells Revealed Paracrine Induction of Interferon Lambda 1.J Virol. 2019 Sep 30;93(20):e00559-19. doi: 10.1128/JVI.00559-19. Print 2019 Oct 15.
91 IL-27 promotes NK cell effector functions via Maf-Nrf2 pathway during influenza infection.Sci Rep. 2019 Mar 21;9(1):4984. doi: 10.1038/s41598-019-41478-6.
92 IL-36 receptor deletion attenuates lung injury and decreases mortality in murine influenza pneumonia.Mucosal Immunol. 2017 Jul;10(4):1043-1055. doi: 10.1038/mi.2016.107. Epub 2016 Dec 14.
93 IL-33 drives influenza-induced asthma exacerbations by halting innate and adaptive antiviral immunity.J Allergy Clin Immunol. 2019 Apr;143(4):1355-1370.e16. doi: 10.1016/j.jaci.2018.08.051. Epub 2018 Oct 12.
94 Intrinsic 4-1BB signals are indispensable for the establishment of an influenza-specific tissue-resident memory CD8 T-cell population in the lung.Mucosal Immunol. 2017 Sep;10(5):1294-1309. doi: 10.1038/mi.2016.124. Epub 2017 Jan 4.
95 Glucocorticoids suppress inflammation via the upregulation of negative regulator IRAK-M.Nat Commun. 2015 Jan 14;6:6062. doi: 10.1038/ncomms7062.
96 IRF and STAT Transcription Factors - From Basic Biology to Roles in Infection, Protective Immunity, and Primary Immunodeficiencies.Front Immunol. 2019 Jan 8;9:3047. doi: 10.3389/fimmu.2018.03047. eCollection 2018.
97 Screening of gene signatures for rheumatoid arthritis and osteoarthritis based on bioinformatics analysis.Mol Med Rep. 2016 Aug;14(2):1587-93. doi: 10.3892/mmr.2016.5423. Epub 2016 Jun 23.
98 Influenza Infection in Mice Induces Accumulation of Lung Mast Cells through the Recruitment and Maturation of Mast Cell Progenitors.Front Immunol. 2017 Mar 22;8:310. doi: 10.3389/fimmu.2017.00310. eCollection 2017.
99 Enhanced recognition of human NK receptors after influenza virus infection.J Immunol. 2003 Jul 15;171(2):915-23. doi: 10.4049/jimmunol.171.2.915.
100 Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation.J Virol. 2005 Sep;79(18):12112-6. doi: 10.1128/JVI.79.18.12112-12116.2005.
101 Lanthionine Synthetase C-Like 2 Modulates Immune Responses to Influenza Virus Infection.Front Immunol. 2017 Feb 21;8:178. doi: 10.3389/fimmu.2017.00178. eCollection 2017.
102 Broad-Spectrum Inhibition of Respiratory Virus Infection by MicroRNA Mimics Targeting p38 MAPK Signaling.Mol Ther Nucleic Acids. 2017 Jun 16;7:256-266. doi: 10.1016/j.omtn.2017.03.008. Epub 2017 Apr 6.
103 Evaluation of Mannose Binding Lectin Gene Variants in Pediatric Influenza Virus-Related Critical Illness.Front Immunol. 2019 May 8;10:1005. doi: 10.3389/fimmu.2019.01005. eCollection 2019.
104 Characterization of the murine Th2 response to immunization with liposomal M2e influenza vaccine.Vaccine. 2011 Jun 15;29(27):4460-8. doi: 10.1016/j.vaccine.2011.04.040. Epub 2011 May 3.
105 How are children who are delayed in the Childhood Vaccination Programme vaccinated: A nationwide register-based cohort study of Danish children aged 15-24 months and semi-structured interviews with vaccination providers.Scand J Public Health. 2020 Feb;48(1):96-105. doi: 10.1177/1403494818786146. Epub 2018 Jul 19.
106 Aging Impairs Alveolar Macrophage Phagocytosis and Increases Influenza-Induced Mortality in Mice.J Immunol. 2017 Aug 1;199(3):1060-1068. doi: 10.4049/jimmunol.1700397. Epub 2017 Jun 23.
107 Antiviral effects of Ma Huang Tang against H1N1 influenza virus infection in vitro and in an ICR pneumonia mouse model.Biomed Pharmacother. 2018 Jun;102:1161-1175. doi: 10.1016/j.biopha.2018.03.161. Epub 2018 Apr 6.
108 Cutting Edge: Check Your Mice-A Point Mutation in the Ncr1 Locus Identified in CD45.1 Congenic Mice with Consequences in Mouse Susceptibility to Infection.J Immunol. 2018 Mar 15;200(6):1982-1987. doi: 10.4049/jimmunol.1701676. Epub 2018 Feb 9.
109 Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8(+) T Cell Function and Impaired Viral Clearance.J Virol. 2017 Aug 10;91(17):e00377-17. doi: 10.1128/JVI.00377-17. Print 2017 Sep 1.
110 NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2110-9. doi: 10.1073/pnas.1322118111. Epub 2014 May 5.
111 2D-SAR, Topomer CoMFA and molecular docking studies on avian influenza neuraminidase inhibitors.Comput Struct Biotechnol J. 2018 Dec 7;17:39-48. doi: 10.1016/j.csbj.2018.11.007. eCollection 2019.
112 Contribution of the Purinergic Receptor P2X7 to Development of Lung Immunopathology during Influenza Virus Infection.mBio. 2017 Mar 28;8(2):e00229-17. doi: 10.1128/mBio.00229-17.
113 Characteristics of influenza H13N8 subtype virus firstly isolated from Qinghai Lake Region, China.Virol J. 2017 Sep 18;14(1):180. doi: 10.1186/s12985-017-0842-1.
114 Characterization and mechanisms of anti-influenza virus metabolites isolated from the Vietnamese medicinal plant Polygonum chinense.BMC Complement Altern Med. 2017 Mar 21;17(1):162. doi: 10.1186/s12906-017-1675-6.
115 Influenza Vaccination Coverage Among Health Care Personnel - United States, 2016-17 Influenza Season.MMWR Morb Mortal Wkly Rep. 2017 Sep 29;66(38):1009-1015. doi: 10.15585/mmwr.mm6638a1.
116 Molecular diagnosis and characterization of a culture-negative mycotic aneurysm due to ST54 Haemophilus influenzae type b with PBP 3 alterations.J Infect Chemother. 2018 Jul;24(7):570-572. doi: 10.1016/j.jiac.2017.12.013. Epub 2018 Jan 17.
117 Identification of Polo-like kinases as potential novel drug targets for influenza A virus.Sci Rep. 2017 Aug 17;7(1):8629. doi: 10.1038/s41598-017-08942-7.
118 Prion Protein is a Novel Modulator of Influenza: Potential Implications for Anti-Influenza Therapeutics.Curr Issues Mol Biol. 2020;37:21-32. doi: 10.21775/cimb.037.021. Epub 2019 Dec 9.
119 Two mutations in the C-terminal domain of influenza virus RNA polymerase PB2 enhance transcription by enhancing cap-1 RNA binding activity.Biochim Biophys Acta. 2012 Jan;1819(1):78-83. doi: 10.1016/j.bbagrm.2011.11.006. Epub 2011 Nov 30.
120 Prevention of influenza virus induced bacterial superinfection by standardized Echinacea purpurea, via regulation of surface receptor expression in human bronchial epithelial cells.Virus Res. 2017 Apr 2;233:51-59. doi: 10.1016/j.virusres.2017.03.006. Epub 2017 Mar 7.
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129 Severe influenza pneumonitis in children with inherited TLR3 deficiency.J Exp Med. 2019 Sep 2;216(9):2038-2056. doi: 10.1084/jem.20181621. Epub 2019 Jun 19.
130 A Comparison of Toll-Like Receptor 5 and 21 Ligands as Adjuvants for a Formaldehyde Inactivated H9N2 Avian Influenza Virus Vaccine in Chickens.Viral Immunol. 2018 Nov;31(9):605-612. doi: 10.1089/vim.2018.0072. Epub 2018 Sep 15.
131 Biological sex affects vaccine efficacy and protection against influenza in mice.Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12477-12482. doi: 10.1073/pnas.1805268115. Epub 2018 Nov 19.
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134 TMPRSS2 Is the Major Activating Protease of Influenza A Virus in Primary Human Airway Cells and Influenza B Virus in Human Type II Pneumocytes.J Virol. 2019 Oct 15;93(21):e00649-19. doi: 10.1128/JVI.00649-19. Print 2019 Nov 1.
135 4-1BB Regulates Effector CD8 T Cell Accumulation in the Lung Tissue through a TRAF1-, mTOR-, and Antigen-Dependent Mechanism to Enhance Tissue-Resident Memory T Cell Formation during Respiratory Influenza Infection.J Immunol. 2019 Apr 15;202(8):2482-2492. doi: 10.4049/jimmunol.1800795. Epub 2019 Mar 13.
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138 Verdinexor Targeting of CRM1 is a Promising Therapeutic Approach against RSV and Influenza Viruses.Viruses. 2018 Jan 21;10(1):48. doi: 10.3390/v10010048.
139 Cirsimaritin inhibits influenza A virus replication by downregulating the NF-B signal transduction pathway.Virol J. 2018 May 21;15(1):88. doi: 10.1186/s12985-018-0995-6.
140 Transgenic mouse model for conditional expression of influenza hemagglutinin-tagged human SLC20A1/PIT1.PLoS One. 2019 Oct 15;14(10):e0223052. doi: 10.1371/journal.pone.0223052. eCollection 2019.
141 STAT2 Signaling Regulates Macrophage Phenotype During Influenza and Bacterial Super-Infection.Front Immunol. 2018 Sep 25;9:2151. doi: 10.3389/fimmu.2018.02151. eCollection 2018.
142 Quantification of volume and lipid filling of intracellular vesicles carrying the ABCA3 transporter.Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2330-2335. doi: 10.1016/j.bbamcr.2017.08.013. Epub 2017 Sep 6.
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153 Elucidating the Interactions between Influenza Virus Polymerase and Host Factor ANP32A.J Virol. 2020 Jan 17;94(3):e01353-19. doi: 10.1128/JVI.01353-19. Print 2020 Jan 17.
154 Attributable Fraction of Influenza Virus Detection to Mild and Severe Respiratory Illnesses in HIV-Infected and HIV-Uninfected Patients, South Africa, 2012-2016.Emerg Infect Dis. 2017 Jul;23(7):1124-1132. doi: 10.3201/eid2307.161959.
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156 Identification of Amino Acid Residues in Influenza A Virus PA-X That Contribute to Enhanced Shutoff Activity.Front Microbiol. 2019 Mar 6;10:432. doi: 10.3389/fmicb.2019.00432. eCollection 2019.
157 BET 1: Oseltamivir use for quicker alleviation of symptoms, fewer hospital admissions and lower mortality in adult patients with influenza B.Emerg Med J. 2019 Jan;36(1):55-56. doi: 10.1136/emermed-2018-208381.1.
158 Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity.Respir Res. 2019 May 21;20(1):94. doi: 10.1186/s12931-019-1066-2.
159 Conserved HA-peptide NG34 formulated in pCMV-CTLA4-Ig reduces viral shedding in pigs after a heterosubtypic influenza virus SwH3N2 challenge.PLoS One. 2019 Mar 1;14(3):e0212431. doi: 10.1371/journal.pone.0212431. eCollection 2019.
160 Enhanced Immune Responses Conferring Cross-Protection by Skin Vaccination With a Tri-Component Influenza Vaccine Using a Microneedle Patch.Front Immunol. 2018 Jul 30;9:1705. doi: 10.3389/fimmu.2018.01705. eCollection 2018.
161 p97: An Emerging Target for Cancer, Neurodegenerative Diseases, and Viral Infections.J Med Chem. 2020 Mar 12;63(5):1892-1907. doi: 10.1021/acs.jmedchem.9b01318. Epub 2019 Oct 9.
162 Pregnancy Induces a Steady-State Shift in Alveolar Macrophage M1/M2 Phenotype That Is Associated With a Heightened Severity of Influenza Virus Infection: Mechanistic Insight Using Mouse Models.J Infect Dis. 2019 May 5;219(11):1823-1831. doi: 10.1093/infdis/jiy732.
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166 Influenza A virus M2 protein triggers mitochondrial DNA-mediated antiviral immune responses.Nat Commun. 2019 Oct 11;10(1):4624. doi: 10.1038/s41467-019-12632-5.
167 Adolescent Isolation Interacts With DISC1 Point Mutation to Impair Adult Social Memory and Synaptic Functions in the Hippocampus.Front Cell Neurosci. 2018 Aug 2;12:238. doi: 10.3389/fncel.2018.00238. eCollection 2018.
168 Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation.Virology. 2011 Apr 25;413(1):93-102. doi: 10.1016/j.virol.2011.02.012. Epub 2011 Mar 5.
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170 Alteration of Flt3-Ligand-dependent de novo generation of conventional dendritic cells during influenza infection contributes to respiratory bacterial superinfection.PLoS Pathog. 2018 Oct 29;14(10):e1007360. doi: 10.1371/journal.ppat.1007360. eCollection 2018 Oct.
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172 FUT2 Variants Confer Susceptibility to Familial Otitis Media.Am J Hum Genet. 2018 Nov 1;103(5):679-690. doi: 10.1016/j.ajhg.2018.09.010. Epub 2018 Oct 25.
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174 Luteolin decreases the yield of influenza A virus in vitro by interfering with the coat protein I complex expression.J Nat Med. 2019 Jun;73(3):487-496. doi: 10.1007/s11418-019-01287-7. Epub 2019 Feb 13.
175 G Protein Pathway Suppressor 1 Promotes Influenza Virus Polymerase Activity by Activating the NF-B Signaling Pathway.mBio. 2019 Dec 17;10(6):e02867-19. doi: 10.1128/mBio.02867-19.
176 Evidence for a novel mechanism of influenza A virus host adaptation modulated by PB2-627.FEBS J. 2019 Sep;286(17):3389-3400. doi: 10.1111/febs.14867. Epub 2019 Jul 5.
177 IL-17C-mediated innate inflammation decreases the response to PD-1 blockade in a model of Kras-driven lung cancer.Sci Rep. 2019 Jul 17;9(1):10353. doi: 10.1038/s41598-019-46759-8.
178 IL-22Ra1 is induced during influenza infection by direct and indirect TLR3 induction of STAT1.Respir Res. 2019 Aug 15;20(1):184. doi: 10.1186/s12931-019-1153-4.
179 Human interactome of the influenza B virus NS1 protein.J Gen Virol. 2017 Sep;98(9):2267-2273. doi: 10.1099/jgv.0.000909. Epub 2017 Sep 4.
180 Novel influenza inhibitors designed to target PB1 interactions with host importin RanBP5.Antiviral Res. 2019 Apr;164:81-90. doi: 10.1016/j.antiviral.2019.02.003. Epub 2019 Feb 8.
181 Protease-Activated Receptor 2 Agonist as Adjuvant: Augmenting Development of Protective Memory CD8 T Cell Responses Induced by Influenza Virosomes.J Immunol. 2019 Jul 15;203(2):441-452. doi: 10.4049/jimmunol.1800915. Epub 2019 Jun 10.
182 KLRD1-expressing natural killer cells predict influenza susceptibility.Genome Med. 2018 Jun 14;10(1):45. doi: 10.1186/s13073-018-0554-1.
183 Evaluation of clinical applicability of reverse transcription-loop-mediated isothermal amplification assay for detection and subtyping of Influenza A viruses.J Virol Methods. 2018 Mar;253:18-25. doi: 10.1016/j.jviromet.2017.12.005. Epub 2017 Dec 15.
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185 Comparative evaluation of the CerTest VIASURE flu A, B & RSV real time RT-PCR detection kit on the BD MAX system versus a routine in-house assay for detection of influenza A and B virus during the 2016/17 influenza season.J Clin Virol. 2018 Feb-Mar;99-100:35-37. doi: 10.1016/j.jcv.2017.12.010. Epub 2017 Dec 21.
186 Integrated Safety Profile of a New Approved, Fully Liquid DTaP5-HB-IPV-Hib Vaccine.Pediatr Infect Dis J. 2019 Apr;38(4):439-443. doi: 10.1097/INF.0000000000002257.
187 MORC3 Is a Target of the Influenza A Viral Protein NS1.Structure. 2019 Jun 4;27(6):1029-1033.e3. doi: 10.1016/j.str.2019.03.015. Epub 2019 Apr 18.
188 Type 1 Conventional CD103(+) Dendritic Cells Control Effector CD8(+) T Cell Migration, Survival, and Memory Responses During Influenza Infection.Front Immunol. 2018 Dec 21;9:3043. doi: 10.3389/fimmu.2018.03043. eCollection 2018.
189 Total synthesis of dryocrassin ABBA and its analogues with potential inhibitory activity against drug-resistant neuraminidases.Bioorg Med Chem. 2019 Sep 1;27(17):3846-3852. doi: 10.1016/j.bmc.2019.07.013. Epub 2019 Jul 8.
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193 Microbial virulence, molecular epidemiology and pathogenic factors of fluoroquinolone-resistant Haemophilus influenzae infections in Guangzhou, China.Ann Clin Microbiol Antimicrob. 2018 Nov 23;17(1):41. doi: 10.1186/s12941-018-0290-9.
194 Host Factor Nucleoporin 93 Is Involved in the Nuclear Export of Influenza Virus RNA.Front Microbiol. 2018 Jul 24;9:1675. doi: 10.3389/fmicb.2018.01675. eCollection 2018.
195 Investigating the role of Ebp1 in Chandipura virus infection.J Biosci. 2019 Jun;44(2):31.
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197 Lung epithelial protein disulfide isomerase A3 (PDIA3) plays an important role in influenza infection, inflammation, and airway mechanics.Redox Biol. 2019 Apr;22:101129. doi: 10.1016/j.redox.2019.101129. Epub 2019 Jan 29.
198 Inhibition of Ongoing Influenza A Virus Replication Reveals Different Mechanisms of RIG-I Activation.J Virol. 2019 Mar 5;93(6):e02066-18. doi: 10.1128/JVI.02066-18. Print 2019 Mar 15.
199 Directed Evolution of an Influenza Reporter Virus To Restore Replication and Virulence and Enhance Noninvasive Bioluminescence Imaging in Mice.J Virol. 2018 Jul 31;92(16):e00593-18. doi: 10.1128/JVI.00593-18. Print 2018 Aug 15.
200 Expression and Immunogenicity of M2e Peptide of Avian Influenza Virus H5N1 Fused to Ricin Toxin B Chain Produced in Duckweed Plants.Front Chem. 2018 Feb 13;6:22. doi: 10.3389/fchem.2018.00022. eCollection 2018.
201 Blimp-1 Rather Than Hobit Drives the Formation of Tissue-Resident Memory CD8(+) T Cells in the Lungs.Front Immunol. 2019 Mar 7;10:400. doi: 10.3389/fimmu.2019.00400. eCollection 2019.
202 A Novel Sulfonated Derivative of -Cyclodextrin Effectively Inhibits Influenza A Virus Infection in vitro and in vivo.Acta Naturae. 2019 Jul-Sep;11(3):20-30. doi: 10.32607/20758251-2019-11-3-20-30.
203 Comparison of influenza disease burden in older populations of Hong Kong and Brisbane: the impact of influenza and pneumococcal vaccination.BMC Infect Dis. 2019 Feb 14;19(1):162. doi: 10.1186/s12879-019-3735-7.
204 Subclinical Cytomegalovirus Infection Is Associated with Altered Host Immunity, Gut Microbiota, and Vaccine Responses.J Virol. 2018 Jun 13;92(13):e00167-18. doi: 10.1128/JVI.00167-18. Print 2018 Jul 1.
205 Effect of mobile phone text messaging for improving the uptake of influenza vaccination in patients with rare diseases.Vaccine. 2019 Aug 23;37(36):5257-5264. doi: 10.1016/j.vaccine.2019.07.062. Epub 2019 Jul 25.
206 Destabilization of the human RED-SMU1 splicing complex as a basis for host-directed antiinfluenza strategy.Proc Natl Acad Sci U S A. 2019 May 28;116(22):10968-10977. doi: 10.1073/pnas.1901214116. Epub 2019 May 10.
207 The Interferon-Inducible Proteoglycan Testican-2/SPOCK2 Functions as a Protective Barrier against Virus Infection of Lung Epithelial Cells.J Virol. 2019 Sep 30;93(20):e00662-19. doi: 10.1128/JVI.00662-19. Print 2019 Oct 15.
208 Alterations in sialic-acid O-acetylation glycoforms during murine erythrocyte development.Glycobiology. 2019 Mar 1;29(3):222-228. doi: 10.1093/glycob/cwy110.
209 The C-Terminal Effector Domain of Non-Structural Protein 1 of Influenza A Virus Blocks IFN- Production by Targeting TNF Receptor-Associated Factor 3.Front Immunol. 2017 Jul 3;8:779. doi: 10.3389/fimmu.2017.00779. eCollection 2017.
210 Inhibition of Influenza A Virus Replication by TRIM14 via Its Multifaceted Protein-Protein Interaction With NP.Front Microbiol. 2019 Feb 26;10:344. doi: 10.3389/fmicb.2019.00344. eCollection 2019.
211 TRIM41-Mediated Ubiquitination of Nucleoprotein Limits Influenza A Virus Infection.J Virol. 2018 Jul 31;92(16):e00905-18. doi: 10.1128/JVI.00905-18. Print 2018 Aug 15.
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