Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM4C7E6)

Drug Name
BAICALEIN Drug Info
Synonyms
baicalein; 491-67-8; 5,6,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-4H-chromen-4-one; Noroxylin; Biacalein; BaiKalein; Baicelein; UNII-49QAH60606; NSC661431; NSC 661431; CHEMBL8260; 5,6,7-trihydroxy-2-phenylchromen-4-one; CHEBI:2979; FXNFHKRTJBSTCS-UHFFFAOYSA-N; MFCD00017459; 4H-1-Benzopyran-4-one, 5,6,7-trihydroxy-2-phenyl-; 49QAH60606; 5,7-Trihydroxyflavone; 5,6,7-trihydroxy-2-phenyl-chromen-4-one; Sho-saiko-to; SMR000112462; SR-01000597499; Baicalein, 8; Baicalein,(S); 3WL; Baicalein, 14; Baicalein, 98%; AC1NQYPP; Tocris-1761
Indication
Disease Entry ICD 11 Status REF
Influenza virus infection 1E30-1E32 Phase 2 [1]
Cross-matching ID
PubChem CID
5281605
ChEBI ID
CHEBI:2979
CAS Number
CAS 491-67-8
TTD Drug ID
DM4C7E6

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Discontinued Drug(s)
Patented Agent(s)
Investigative Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Arachidonate 5-lipoxygenase (5-LOX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [17]
Diethylcarbamazine DM1TJ8F Elephantiasis Approved [18]
Silymarin DMXBYQR N. A. N. A. Phase 4 [19]
3,4-Dihydroxycinnamic Acid DMVZL26 Thrombocytopenia 3B64 Phase 4 [20]
Avastin+/-Tarceva DMA86FL Non-small-cell lung cancer 2C25.Y Phase 3 [21]
ABT-761 DM3FIC2 Asthma CA23 Phase 3 [22]
Tenidap DMHQRYE Rheumatoid arthritis FA20 Phase 3 [23]
FPL-62064 DMGF8MZ Inflammation 1A00-CA43.1 Phase 3 [24]
Flobufen DMPSG4D Rheumatoid arthritis FA20 Phase 3 [25]
Darbufelone DMYVKM5 Asthma CA23 Phase 2/3 [26]
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Drug(s) Targeting P-selectin (SELP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Crizanlizumab DMAHOVJ Vaso-occlusive crisis BE2Y Approved [27]
GMI-1070 DMJ432G Asthma CA23 Phase 3 [28]
Inclacumab DMXV94M Sickle-cell disorder 3A51 Phase 3 [29]
CY-1503 DML906E Hypertension BA00-BA04 Phase 2/3 [30]
SelG1 DMTQ2K0 Vaso-occlusive crisis BE2Y Phase 2 [31]
RPSGL-Ig DM0BFJ5 Delayed graft function 4B24.0 Phase 2 [32]
PSI-697 DM75FWO Atherosclerosis BD40 Phase 1 [33]
CDP-850 DMWHQM3 Solid tumour/cancer 2A00-2F9Z Discontinued in Phase 2 [34]
CY-1787 DMWY2NT Allergy 4A80-4A85 Discontinued in Phase 1 [35]
PURPUROGALLIN DM63O4F N. A. N. A. Terminated [3]
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Drug(s) Targeting Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [36]
Nafamostat DMU1XOD Pancreatitis DC31-DC34 Approved [37]
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [38]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [39]
Enbrel DM7RNP3 Arthritis FA20 Approved [40]
Golimumab DMHZV7X Psoriatic arthritis FA21 Approved [41]
Certolizumab DM5CL9Z Rheumatoid arthritis FA20 Approved [42]
Etanercept DMCV109 Arthritis FA20 Approved [43]
Adalimumab DMQMV1B Crohn disease DD70 Approved [44]
Infliximab DMH7OIA Crohn disease DD70 Approved [45]
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Drug(s) Targeting Xanthine dehydrogenase/oxidase (XDH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Allopurinol DMLPAOB Gout FA25 Approved [46]
Febuxostat DMDEXQ0 Hyperuricaemia 5C55.Y Approved [47]
Fosdenopterin DMR0TYK Molybdenum cofactor deficiency 5B5K.A Approved [48]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [49]
Oxypurinol DMURH4X Heart failure BD10-BD13 Phase 2/3 [50]
Topiroxostat DMA04DE Gout FA25 Phase 2 [51]
TMX-049 DME8PFQ Diabetic nephropathy GB61.Z Phase 2 [52]
LC-350189 DMHT3CB Gout FA25 Phase 1 [53]
Azaindole derivative 5 DMD2BL3 N. A. N. A. Patented [54]
Fused heterocyclic compound 3 DM2QVHY N. A. N. A. Patented [54]
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Drug(s) Targeting L-selectin (SELL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
GMI-1070 DMJ432G Asthma CA23 Phase 3 [28]
PURPUROGALLIN DM63O4F N. A. N. A. Terminated [3]
Hu Dreg 55 DMK1VHF Psoriasis vulgaris EA90 Terminated [55]
2,3,4-trihydroxybenzoic acid DMWHK35 Discovery agent N.A. Investigative [3]
LD201t1 DMC5XQ6 Inflammation 1A00-CA43.1 Investigative [56]
Drug(s) Targeting Prolyl endopeptidase (PREP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ALV-003 DMXSFA0 Coeliac disease DA95 Phase 2 [57]
ONO-1603 DMKIZAL Cognitive impairment 6D71 Phase 2 [58]
S-17092-1 DMYR1K8 Cognitive impairment 6D71 Phase 1 [59]
JTP-4819 DMI0UJS Cognitive impairment 6D71 Discontinued in Phase 2 [60]
Z-321 DMLO2QY Parkinson disease 8A00.0 Discontinued in Phase 1 [61]
BAICALIN DMY1TLZ Human immunodeficiency virus infection 1C62 Terminated [62]
Y-29794 DMLAVES N. A. N. A. Terminated [62]
Double Oxidized Cysteine DM6TU84 Discovery agent N.A. Investigative [63]
Monothioglycerol DMENSOZ Discovery agent N.A. Investigative [63]
Z-Pro-Prolinal DM43O2U Discovery agent N.A. Investigative [64]
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Drug(s) Targeting Lactoylglutathione lyase (GLO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
NARINGENIN DMHAZLM N. A. N. A. Phase 1 [4]
2-Sulfhydryl-Ethanol DMJBO3D Discovery agent N.A. Investigative [65]
KAEMPFEROL DMHEMUB Discovery agent N.A. Investigative [4]
S-(N-butyl-N-hydroxycarbamoyl)glutathione DMU7EQV Discovery agent N.A. Investigative [66]
S-(N-heptyl-N-hydroxycarbamoyl)glutathione DMV6T1Q Discovery agent N.A. Investigative [66]
S-(N-propyl-N-hydroxycarbamoyl)glutathione DMRFKZ6 Discovery agent N.A. Investigative [66]
S-(N-Hydroxy-N-Iodophenylcarbamoyl)Glutathione DM1AHIW Discovery agent N.A. Investigative [65]
S-(N-pentyl-N-hydroxycarbamoyl)glutathione DM4E9J2 Discovery agent N.A. Investigative [66]
S-(N-methyl-N-hydroxycarbamoyl)glutathione DM1C9W3 Discovery agent N.A. Investigative [66]
S-(N-4bromophenyl-N-hydroxycarbamoyl)glutathione DM3FXPV Discovery agent N.A. Investigative [66]
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Drug(s) Affected By Aryl hydrocarbon receptor (AHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [69]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [70]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [71]
Quercetin DM3NC4M Obesity 5B81 Approved [72]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [73]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [75]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [76]
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Drug(s) Affected By Arylamine N-acetyltransferase 1 (NAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [77]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [78]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [79]
Methotrexate DM2TEOL Anterior urethra cancer Approved [77]
Testosterone DM7HUNW Hot flushes GA30 Approved [80]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [80]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [81]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Folic Acid DMEMBJC Colorectal carcinoma Approved [77]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [83]
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Drug(s) Affected By 11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [84]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [85]
Testosterone DM7HUNW Hot flushes GA30 Approved [80]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [80]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [89]
Ethanol DMDRQZU Chronic pain MG30 Approved [90]
Oxymetholone DMFXUT8 Aplastic anemia 3A70 Approved [91]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [92]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [93]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [94]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [95]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [96]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [97]
Ethacrynic acid DM60QMR Edema MG29 Approved [98]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [99]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [100]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [101]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [102]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [102]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [102]
Capsaicin DMGMF6V Back pain ME84.Z Approved [103]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [104]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [105]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [106]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [107]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [108]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [109]
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Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [110]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [113]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [114]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [114]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [115]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [116]
Capsaicin DMGMF6V Back pain ME84.Z Approved [117]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [118]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [119]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [120]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [121]
Estrone DM5T6US Acne vulgaris ED80 Approved [122]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [123]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [124]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [125]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [126]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [127]
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Drug(s) Affected By Polyunsaturated fatty acid lipoxygenase ALOX15 (ALOX15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [129]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [132]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [133]
3,4-Dihydroxycinnamic Acid DMVZL26 Thrombocytopenia 3B64 Phase 4 [134]
EXISULIND DMBY56U Colorectal cancer 2B91.Z Phase 3 [135]
CP-461 DMEYMTX Inflammatory bowel disease DD72 Phase 2 [136]
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Drug(s) Affected By Cytochrome P450 2B6 (CYP2B6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [137]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [138]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [139]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [140]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [141]
Clopidogrel DMOL54H Acute coronary syndrome BA41 Approved [142]
Artemisinin DMOY7W3 Malaria 1F40-1F45 Approved [143]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [144]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [145]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [146]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 3 (NR1I3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [147]
Quercetin DM3NC4M Obesity 5B81 Approved [148]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [149]
Artemether DM48QOT Malaria 1F40-1F45 Approved [150]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [151]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [152]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [75]
Estrone DM5T6US Acne vulgaris ED80 Approved [153]
Leflunomide DMR8ONJ Arthritis FA20 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [81]
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Drug(s) Affected By Cytochrome P450 2E1 (CYP2E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fomepizole DM6VOWQ Athylene glycol or methanol poisoning NE61 Approved [155]
Ademetionine DMYQDBO Hepatic fibrosis DB93.0 Approved [156]
Theophylline DMRJFN9 Bronchitis CA20 Approved [109]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [157]
Ethanol DMDRQZU Chronic pain MG30 Approved [158]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [159]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [160]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Didanosine DMI2QPE Human immunodeficiency virus infection 1C62 Approved [109]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [161]
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Drug(s) Affected By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [162]
Dapsone DM4LT8A Acne vulgaris ED80 Approved [114]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [113]
Capsaicin DMGMF6V Back pain ME84.Z Approved [103]
Zafirlukast DMHNQOG Asthma CA23 Approved [163]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [114]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [164]
Fluconazole DMOWZ6B Cryptococcal meningitis Approved [113]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [114]
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Drug(s) Affected By Cytochrome P450 2C19 (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [111]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [161]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [113]
Chloramphenicol DMFXEWT Bacterial infection 1A00-1C4Z Approved [137]
Capsaicin DMGMF6V Back pain ME84.Z Approved [103]
Pentamidine DMHZJCG African trypanosomiasis 1F51 Approved [114]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [105]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [114]
Desipramine DMT2FDC Attention deficit hyperactivity disorder 6A05.Z Approved [161]
Amitriptyline DMK7F9S Depression 6A70-6A7Z Approved [109]
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Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [165]
Gefitinib DM15F0X Colon adenocarcinoma Approved [166]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [167]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [168]
Etretinate DM2CZFA Keratosis ED56 Approved [169]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [170]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [171]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [173]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [174]
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Drug(s) Affected By Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [175]
Gefitinib DM15F0X Colon adenocarcinoma Approved [176]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [177]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [178]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [179]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [180]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [181]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [182]
Selenium DM25CGV N. A. N. A. Approved [183]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [184]
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Drug(s) Affected By Urokinase-type plasminogen activator (PLAU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [185]
Methotrexate DM2TEOL Anterior urethra cancer Approved [186]
Quercetin DM3NC4M Obesity 5B81 Approved [187]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [188]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [74]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [185]
Panobinostat DM58WKG Chronic graft versus host disease Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Leflunomide DMR8ONJ Arthritis FA20 Approved [191]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [192]
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Drug(s) Affected By Insulin (INS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Epinephrine DM3KJBC Acute asthma CA23 Approved [195]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [196]
Fructose DM43AN2 Vomiting MD90 Approved [197]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [198]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [199]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [200]
Propranolol DM79NTF Angina pectoris BA40 Approved [201]
Testosterone DM7HUNW Hot flushes GA30 Approved [202]
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Drug(s) Affected By Erythropoietin (EPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [203]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [204]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [205]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [81]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [207]
Fenoterol DMIP3ZV Asthma CA23 Approved [208]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [209]
Enalapril DMNFUZR Congestive heart failure BD10 Approved [210]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [211]
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Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [212]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [213]
Gefitinib DM15F0X Colon adenocarcinoma Approved [214]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [215]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [178]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [216]
Quercetin DM3NC4M Obesity 5B81 Approved [217]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [218]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [215]
Estrone DM5T6US Acne vulgaris ED80 Approved [219]
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Drug(s) Affected By Granulocyte-macrophage colony-stimulating factor (CSF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [220]
Quercetin DM3NC4M Obesity 5B81 Approved [221]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [97]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [222]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [223]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [224]
Testosterone DM7HUNW Hot flushes GA30 Approved [225]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [226]
Acetylcholine DMDF79Z Cataract 9B10 Approved [227]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [228]
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Drug(s) Affected By Receptor tyrosine-protein kinase erbB-2 (ERBB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trastuzumab DMZQOUX Breast cancer 2C60-2C65 Approved [109]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [229]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [230]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [231]
Gefitinib DM15F0X Colon adenocarcinoma Approved [232]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [233]
Selenium DM25CGV N. A. N. A. Approved [234]
Methotrexate DM2TEOL Anterior urethra cancer Approved [235]
Quercetin DM3NC4M Obesity 5B81 Approved [236]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [237]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [238]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [239]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [240]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [241]
Paclitaxel DMLB81S Breast carcinoma Approved [242]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [243]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [244]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [245]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [246]
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Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [247]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [248]
Fructose DM43AN2 Vomiting MD90 Approved [109]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [250]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [181]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [251]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [252]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [253]
Methotrexate DM2TEOL Anterior urethra cancer Approved [254]
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Drug(s) Affected By Retinoblastoma-associated protein (RB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [255]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [256]
Gefitinib DM15F0X Colon adenocarcinoma Approved [257]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [258]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [233]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [259]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [260]
Methotrexate DM2TEOL Anterior urethra cancer Approved [261]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [262]
Quercetin DM3NC4M Obesity 5B81 Approved [236]
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Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [263]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [264]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [165]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [265]
Selenium DM25CGV N. A. N. A. Approved [266]
Etretinate DM2CZFA Keratosis ED56 Approved [169]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [267]
Methotrexate DM2TEOL Anterior urethra cancer Approved [235]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [268]
Quercetin DM3NC4M Obesity 5B81 Approved [236]
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Drug(s) Affected By Glycogen phosphorylase, liver form (PYGL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Testosterone DM7HUNW Hot flushes GA30 Approved [225]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [270]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [271]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [272]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [271]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [273]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [274]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [275]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [276]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [277]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [278]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [279]
Cepharanthine DM9Y5JB N. A. N. A. Approved [280]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [281]
Clozapine DMFC71L Schizophrenia 6A20 Approved [282]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [283]
Trifluoperazine DMKBYWI Anxiety Approved [284]
Olanzapine DMPFN6Y Bipolar depression Approved [282]
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Drug(s) Affected By 72 kDa type IV collagenase (MMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [285]
Selenium DM25CGV N. A. N. A. Approved [183]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [286]
Quercetin DM3NC4M Obesity 5B81 Approved [287]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [288]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [289]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [290]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [190]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [291]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [292]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [293]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [294]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [295]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [296]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [109]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [297]
Verapamil DMA7PEW Angina pectoris BA40 Approved [298]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [299]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [300]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [301]
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Drug(s) Affected By Glycogen phosphorylase, brain form (PYGB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [234]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [302]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [81]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [272]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [273]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [275]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [303]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [304]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [305]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [306]
Selenium DM25CGV N. A. N. A. Approved [266]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [307]
Methotrexate DM2TEOL Anterior urethra cancer Approved [235]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [308]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [309]
Quercetin DM3NC4M Obesity 5B81 Approved [236]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [188]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
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Drug(s) Affected By Proto-oncogene tyrosine-protein kinase Src (SRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bosutinib DMTI8YE Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [311]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [312]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Quercetin DM3NC4M Obesity 5B81 Approved [313]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [314]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [315]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [316]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cystic fibrosis transmembrane conductance regulator (CFTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivacaftor DMZC1HS Cystic fibrosis CA25 Approved [317]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [265]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [318]
Quercetin DM3NC4M Obesity 5B81 Approved [319]
Miglustat DM5J64S Niemann-Pick disease type C Approved [320]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [321]
Milrinone DM8TUPF Congestive heart failure BD10 Approved [318]
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [322]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [322]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [323]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pyruvate kinase PKM (PKM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [324]
Selenium DM25CGV N. A. N. A. Approved [234]
Epinephrine DM3KJBC Acute asthma CA23 Approved [325]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [326]
Panobinostat DM58WKG Chronic graft versus host disease Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [327]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [328]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [329]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [330]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [263]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [264]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [251]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [265]
Selenium DM25CGV N. A. N. A. Approved [266]
Etretinate DM2CZFA Keratosis ED56 Approved [169]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [331]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [332]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [170]
Methotrexate DM2TEOL Anterior urethra cancer Approved [333]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Matrix metalloproteinase-9 (MMP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [334]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [67]
Gefitinib DM15F0X Colon adenocarcinoma Approved [335]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [336]
Selenium DM25CGV N. A. N. A. Approved [183]
Pentosan Polysulfate DM2HRKE Interstitial cystitis GC00.3 Approved [337]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [338]
Methotrexate DM2TEOL Anterior urethra cancer Approved [339]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [340]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [341]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein kinase C alpha type (PRKCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [342]
Quercetin DM3NC4M Obesity 5B81 Approved [343]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [344]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
Panobinostat DM58WKG Chronic graft versus host disease Approved [189]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [328]
Leflunomide DMR8ONJ Arthritis FA20 Approved [191]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [272]
Capsaicin DMGMF6V Back pain ME84.Z Approved [345]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Quercetin DM3NC4M Obesity 5B81 Approved [346]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [302]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [347]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [348]
Masoprocol DMMVNZ0 Prostate cancer 2C82.0 Approved [346]
Bortezomib DMNO38U Leukemia Approved [349]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [346]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [350]
Milchsaure DM462BT Pruritus EC90 Investigative [351]
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Drug(s) Affected By Nuclear factor NF-kappa-B p105 subunit (NFKB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [352]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [353]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [181]
Gefitinib DM15F0X Colon adenocarcinoma Approved [354]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [233]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [355]
Methotrexate DM2TEOL Anterior urethra cancer Approved [356]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [357]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [358]
Quercetin DM3NC4M Obesity 5B81 Approved [359]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [229]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [264]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [231]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [119]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [360]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [260]
Methotrexate DM2TEOL Anterior urethra cancer Approved [333]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [268]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [361]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
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Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [362]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [363]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [301]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [213]
Gefitinib DM15F0X Colon adenocarcinoma Approved [176]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [258]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [364]
Selenium DM25CGV N. A. N. A. Approved [234]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [365]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [366]
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Drug(s) Affected By Mitogen-activated protein kinase 3 (MAPK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [367]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [368]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [369]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [300]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [370]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [371]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [372]
Gefitinib DM15F0X Colon adenocarcinoma Approved [373]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [374]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [375]
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Drug(s) Affected By Mitogen-activated protein kinase 1 (MAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ethanol DMDRQZU Chronic pain MG30 Approved [376]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [368]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [377]
Paclitaxel DMLB81S Breast carcinoma Approved [378]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [379]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [367]
Urokinase DM0GOUD Myocardial infarction BA41-BA43 Approved [109]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [380]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [300]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [370]
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Drug(s) Affected By RAC-alpha serine/threonine-protein kinase (AKT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [381]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [382]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [244]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [301]
Gefitinib DM15F0X Colon adenocarcinoma Approved [383]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [384]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [385]
Selenium DM25CGV N. A. N. A. Approved [234]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [386]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [365]
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Drug(s) Affected By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [387]
Folic Acid DMEMBJC Colorectal carcinoma Approved [388]
Methotrexate DM2TEOL Anterior urethra cancer Approved [389]
Quercetin DM3NC4M Obesity 5B81 Approved [390]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [391]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [392]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [393]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [394]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [395]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [395]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [380]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [265]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [396]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [347]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [397]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [398]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
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Drug(s) Affected By Neurogenic locus notch homolog protein 1 (NOTCH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [399]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [237]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [400]
Propranolol DM79NTF Angina pectoris BA40 Approved [401]
Testosterone DM7HUNW Hot flushes GA30 Approved [225]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [402]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [403]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [273]
Mebendazole DMO14SG Ascariasis 1F62 Approved [404]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [405]
Gefitinib DM15F0X Colon adenocarcinoma Approved [257]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [406]
Selenium DM25CGV N. A. N. A. Approved [234]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [407]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [408]
Quercetin DM3NC4M Obesity 5B81 Approved [359]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [409]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [410]
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Drug(s) Affected By Actin, aortic smooth muscle (ACTA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [411]
Quercetin DM3NC4M Obesity 5B81 Approved [412]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
Panobinostat DM58WKG Chronic graft versus host disease Approved [413]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [414]
Pirfenidone DM6VZFQ Idiopathic pulmonary fibrosis CB03.4 Approved [415]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [416]
Testosterone DM7HUNW Hot flushes GA30 Approved [80]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [417]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [380]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [301]
Selenium DM25CGV N. A. N. A. Approved [234]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [267]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [358]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [418]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [419]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [420]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [421]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis regulator BAX (BAX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [293]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [422]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [297]
Verapamil DMA7PEW Angina pectoris BA40 Approved [298]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [423]
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [424]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [258]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [233]
Meloxicam DM2AR7L Arthritis FA20 Approved [425]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [331]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor HES-1 (HES1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [426]
Selenium DM25CGV N. A. N. A. Approved [234]
Quercetin DM3NC4M Obesity 5B81 Approved [206]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [310]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [269]
Testosterone DM7HUNW Hot flushes GA30 Approved [225]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [80]
Leflunomide DMR8ONJ Arthritis FA20 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [323]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NF-kappa-B inhibitor beta (NFKBIB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [234]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [427]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [428]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [86]
Bortezomib DMNO38U Leukemia Approved [429]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [131]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [303]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [234]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [430]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [431]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hypoxia-inducible factor 1-alpha (HIF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [432]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [433]
Prednisone DM2HG4X Acute asthma CA23 Approved [434]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [434]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [435]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [436]
Epinephrine DM3KJBC Acute asthma CA23 Approved [325]
Quercetin DM3NC4M Obesity 5B81 Approved [437]
Fluoxetine DM3PD2C Bipolar depression Approved [438]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [439]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 22 member 6 (SLC22A6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [440]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [441]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [441]
Quercetin DM3NC4M Obesity 5B81 Approved [442]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [441]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [441]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [443]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [441]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [444]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [441]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Endophilin-A2 (SH3GL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [272]
Clozapine DMFC71L Schizophrenia 6A20 Approved [445]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [159]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [446]
biochanin A DM0HPWY Discovery agent N.A. Investigative [447]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [448]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Hairy/enhancer-of-split related with YRPW motif protein 2 (HEY2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [237]
Panobinostat DM58WKG Chronic graft versus host disease Approved [189]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [449]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [450]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [403]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [451]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [451]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [452]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [453]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hairy/enhancer-of-split related with YRPW motif protein 1 (HEY1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [237]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [454]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [455]
Leflunomide DMR8ONJ Arthritis FA20 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [81]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [82]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [273]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [456]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [457]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [275]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Arachidonate 5-lipoxygenase (5-LOX) TT2J34L LOX5_HUMAN Inhibitor [2]
L-selectin (SELL) TT2IYXF LYAM1_HUMAN Inhibitor [3]
Lactoylglutathione lyase (GLO1) TTV9A7R LGUL_HUMAN Inhibitor [4]
P-selectin (SELP) TTE5VG0 LYAM3_HUMAN Inhibitor [3]
Prolyl endopeptidase (PREP) TTNGKET PPCE_HUMAN Inhibitor [5]
Tumor necrosis factor (TNF) TTF8CQI TNFA_HUMAN Inhibitor [6]
Xanthine dehydrogenase/oxidase (XDH) TT7RJY8 XDH_HUMAN Inhibitor [7]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
11-beta-hydroxysteroid dehydrogenase type 2 (HSD11B2) OTHF4H9U DHI2_HUMAN Gene/Protein Processing [8]
72 kDa type IV collagenase (MMP2) OT5NIWA2 MMP2_HUMAN Gene/Protein Processing [9]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Gene/Protein Processing [10]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Gene/Protein Processing [11]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Gene/Protein Processing [12]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Gene/Protein Processing [13]
Arylamine N-acetyltransferase 1 (NAT1) OTCCNQ3H ARY1_HUMAN Gene/Protein Processing [14]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Gene/Protein Processing [15]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Gene/Protein Processing [16]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Gene/Protein Processing [11]

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