Details of the Drug-Related molecule(s) Interaction Atlas

General Information of DTP (ID: DTUGYRD)

• DTP Name: P-glycoprotein 1 (ABCB1) DTP Info
• Gene Name: P-GP

Molecule-Related Drug & Molecule List

339 Approved Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Abacavir	DMMN36E	Human immunodeficiency virus infection	1C62	Approved	[1]
Acebutolol	DM0TI4U	Hypertension	BA00-BA04	Approved	[2]
Acrivastine	DMTIGA0	Allergic rhinitis	CA08.0	Approved	[3]
Ajmaline	DMDJW5K	Atrial fibrillation	BC81.3	Approved	[4]
Albendazole	DMYZ57N	Echinococcus granulosus infectious disease		Approved	[5]
Aldosterone	DM9S2JW	Hypertension	BA00-BA04	Approved	[6]
Aliskiren	DM1BV7W	Hypertension	BA00-BA04	Approved	[7]
Ambrisentan	DMD1QXW	Pulmonary arterial hypertension	BB01.0	Approved	[8]
Amiodarone	DMUTEX3	Tachyarrhythmias	BC71	Approved	[9]
Amisulpride	DMSJVAM	Schizophrenia	6A20	Approved	[10]
Amitriptyline	DMK7F9S	Depression	6A70-6A7Z	Approved	[11]
Amoxicillin	DMUYNEI	Acute otitis media	AB00	Approved	[2]
Amphotericin B	DMTAJQE	Acne vulgaris	ED80	Approved	[12]
Amprenavir	DMLMXE0	Human immunodeficiency virus infection	1C62	Approved	[9]
Apixaban	DM89JLN	Thrombosis	DB61-GB90	Approved	[13]
Apremilast	DMTWS9E	Psoriasis vulgaris	EA90	Approved	[14]
Aprepitant	DM053KT	Depression	6A70-6A7Z	Approved	[15]
ARRY-162	DM1P6FR	Melanoma	2C30	Approved	[16]
Arsenic trioxide	DM61TA4	Acute lymphoblastic leukaemia	2A85	Approved	[17]
Aspirin	DM672AH	Acute coronary syndrome	BA41	Approved	[11]
Atenolol	DMNKG1Z	Angina pectoris	BA40	Approved	[18]
Atomoxetine	DM5L6HI	Attention deficit hyperactivity disorder	6A05.Z	Approved	[15]
Atorvastatin	DMF28YC	Acute coronary syndrome	BA41	Approved	[14]
Axitinib	DMGVH6N	Renal cell carcinoma	2C90	Approved	[19]
Azathioprine	DMMZSXQ	Lupus nephritis	4A40.0Y	Approved	[11]
Baloxavir marboxil	DM1UV7F	Influenza virus infection	1E30-1E32	Approved	[20]
Baricitinib	DM4ONW5	Rheumatoid arthritis	FA20	Approved	[21]
Beclomethasone	DMZPHIK	Allergic rhinitis	CA08.0	Approved	[22]
Bepridil	DM0RKS4	Chronic/stable angina	BA40.1	Approved	[9]
Beta-acetyldigoxin	DMI6GKT	Cardiovascular disease	BA00-BE2Z	Approved	[23]
Beta-carotene	DM0RXBT	Vitamin deficiency	5B55-5B71	Approved	[12]
Betamethasone	DMAHJEF	Acute adrenal insufficiency		Approved	[24]
BETRIXABAN	DM2C4RF	Venous thromboembolism	BD72	Approved	[25]
BIBW 2992	DMTKD7Q	Non-small-cell lung cancer	2C25.Y	Approved	[26]
Bicalutamide	DMZMSPF	Prostate cancer	2C82.0	Approved	[27]
BOCEPREVIR	DMBSHMF	Hepatitis C virus infection	1E51.1	Approved	[28]
Bortezomib	DMNO38U	Leukemia		Approved	[29]
Bosutinib	DMTI8YE	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[30]
Brilinta	DMBR01X	Acute coronary syndrome	BA41	Approved	[31]
Bromocriptine	DMVE3TK	Acromegaly	5A60.0	Approved	[15]
Bupropion	DM5PCS7	Depression	6A70-6A7Z	Approved	[32]
Cabergoline	DMQ4HIN	Hyperprolactinaemia	5A60.1	Approved	[33]
Canagliflozin	DMFRM1I	Non-insulin dependent diabetes	5A11	Approved	[34]
Cannabidiol	DM0659E	Dravet syndrome	8A61.11	Approved	[31]
Carfilzomib	DM48K0X	Multiple myeloma	2A83	Approved	[35]
Carvedilol	DMHTEAO	Chronic heart failure	BD1Z	Approved	[14]
Cefoperazone	DM53PV8	Bacterial infection	1A00-1C4Z	Approved	[9]
Cefotetan	DM07TX3	Bacteremia	1A73	Approved	[2]
Ceftriaxone	DMCEW64	Acute gonococcal cervicitis		Approved	[9]
Celiprolol hcl	DMD5LBX	Hypertension	BA00-BA04	Approved	[36]
Cepharanthine	DM9Y5JB	N. A.	N. A.	Approved	[37]
Ceritinib	DMB920Z	Non-small-cell lung cancer	2C25.Y	Approved	[38]
Cerivastatin	DMXCM7H	Hyperlipidaemia	5C80	Approved	[39]
Cetirizine	DMOMP9U	Allergic rhinitis	CA08.0	Approved	[40]
Chlorambucil	DMRKE63	Chronic lymphocytic leukaemia	2A82.0	Approved	[9]
Chloramphenicol	DMFXEWT	Bacterial infection	1A00-1C4Z	Approved	[41]
Chloroquine	DMSI5CB	Malaria	1F40-1F45	Approved	[15]
Chlorpromazine	DMBGZI3	Acute intermittent hepatic porphyria	5C58.11	Approved	[9]
Ciclesonide	DM2NA4K	Allergic rhinitis	CA08.0	Approved	[22]
Ciclosporin	DMAZJFX	Graft-versus-host disease	4B24	Approved	[42]
Cimetidine	DMH61ZB	Acid-reflux disorder	DA22	Approved	[9]
Cisplatin	DMRHGI9	Adenocarcinoma	2D40	Approved	[9]
Citalopram	DM2G9AE	Acute coronary syndrome	BA41	Approved	[43]
Clarithromycin	DM4M1SG	Acute maxillary sinusitis		Approved	[9]
Clobazam - Lundbeck	DMW1OQ0	Anxiety disorder	6B00-6B0Z	Approved	[14]
Clofazimine	DMEBOFW	Crohn disease	DD70	Approved	[44]
Clomifene	DMKI7RB	Female infertility	GA31.Z	Approved	[45]
Clomiphene Citrate	DMS51VC	Female infertility	GA31.Z	Approved	[45]
Clomipramine	DMINRKW	Depression	6A70-6A7Z	Approved	[15]
Clonidine	DM6RZ9Q	Attention deficit hyperactivity disorder	6A05.Z	Approved	[11]
Clopidogrel	DMOL54H	Acute coronary syndrome	BA41	Approved	[46]
Clozapine	DMFC71L	Schizophrenia	6A20	Approved	[10]
Colchicine	DM2POTE	Acute gout flare	FA25.0	Approved	[47]
cortisone	DMU5QZX	Atopic dermatitis	EA80	Approved	[24]
Crizotinib	DM4F29C	Non-small-cell lung cancer	2C25.Y	Approved	[48]
Cytarabine	DMZD5QR	Acute lymphoblastic leukaemia	2A85	Approved	[9]
Dabigatran	DMDI6R4	Stroke	8B20	Approved	[49]
Dabrafenib	DMX6OE3	Melanoma	2C30	Approved	[50]
Daclatasvir	DMSFK9V	Hepatitis C virus infection	1E51.1	Approved	[49]
Dactinomycin	DM2YGNW	Adult kidney Wilms tumor		Approved	[51]
Darunavir	DMN3GCH	Human immunodeficiency virus infection	1C62	Approved	[52]
Dasatinib	DMJV2EK	Blast phase chronic myelogenous leukemia, BCR-ABL1 positive		Approved	[53]
Daunorubicin	DMQUSBT	Acute monocytic leukemia		Approved	[9]
Debrisoquin	DMC50ME	Hypertension	BA00-BA04	Approved	[54]
Deflazacort	DMV0RNS	Duchenne dystrophy	8C70	Approved	[31]
Delavirdine	DM3NF5G	Human immunodeficiency virus infection	1C62	Approved	[1]
Desipramine	DMT2FDC	Attention deficit hyperactivity disorder	6A05.Z	Approved	[55]
Desloratadine	DM56YN7	Allergic rhinitis	CA08.0	Approved	[56]
Dexamethasone	DMMWZET	Acute adrenal insufficiency		Approved	[57]
Dexlansoprazole	DM1DBV5	Erosive esophagitis	DA25.0	Approved	[55]
Diazepam	DM08E9O	Alcohol withdrawal		Approved	[58]
Dicloxacillin	DM8EU0Z	Bacterial infection	1A00-1C4Z	Approved	[59]
Diethylstilbestrol	DMN3UXQ	Gonorrheal vaginitis	GA02	Approved	[45]
Digitoxin	DMWVIGP	Arrhythmia	BC9Z	Approved	[60]
Digoxin	DMQCTIH	Arrhythmia	BC9Z	Approved	[61]
Dihydroergocristine	DM5SQ1G	Alcohol dependence	6C40.2	Approved	[62]
Diltiazem	DMAI7ZV	Angina pectoris	BA40	Approved	[9]
Dipyridamole	DMXY30O	Atrial fibrillation	BC81.3	Approved	[15]
Docetaxel	DMDI269	Advanced cancer	2A00-2F9Z	Approved	[63]
Dolutegravir	DMCZGRE	Human immunodeficiency virus infection	1C62	Approved	[14]
Domperidone	DMBDPY0	Gastrointestinal disease	DE2Z	Approved	[10]
Doxorubicin	DMVP5YE	Acute myelogenous leukaemia	2A41	Approved	[64]
Doxycycline	DM7ICNU	Acne vulgaris	ED80	Approved	[9]
DU-176b	DMCIJBH	Atrial fibrillation	BC81.3	Approved	[65]
Efavirenz	DMC0GSJ	Human immunodeficiency virus infection	1C62	Approved	[2]
Eletriptan	DMW649X	Migraine	8A80	Approved	[15]
Eliglustat tartrate	DMSRZAO	Metabolic disorder	5C50-5D2Z	Approved	[31]
Emetine	DMCT2YF	Hepatitis virus infection	1E50-1E51	Approved	[51]
Empagliflozin	DMRF9YK	Type-1 diabetes	5A10	Approved	[31]
Epinastine	DMX0K3Q	Allergic conjunctivitis	9A60.02	Approved	[66]
Epirubicin	DMPDW6T	Solid tumour/cancer	2A00-2F9Z	Approved	[9]
Ergotamine	DMKR3C5	Cluster headache	8A81.0	Approved	[15]
Erlotinib	DMCMBHA	Adrenal gland neoplasm		Approved	[67]
Erythromycin	DM4K7GQ	Acne vulgaris	ED80	Approved	[68]
Eslicarbazepine acetate	DMREUZV	N. A.	N. A.	Approved	[69]
Estradiol	DMUNTE3	Acne vulgaris	ED80	Approved	[45]
Estriol	DMOEM2I	Hormone deficiency	5A61.1	Approved	[70]
Estrone	DM5T6US	Acne vulgaris	ED80	Approved	[70]
Estrone sulfate	DMVBIZL	Atrophic vaginitis	GA30.2	Approved	[39]
Ethinyl Estradiol	DMODJ40	Acne vulgaris	ED80	Approved	[70]
Etoposide	DMNH3PG	Acute myelogenous leukaemia	2A41	Approved	[71]
Everolimus	DM8X2EH	Advanced cancer	2A00-2F9Z	Approved	[72]
Ezetimibe	DM7A8TW	Atherosclerosis	BD40	Approved	[73]
Famciclovir	DMJHLSD	Meniere disease	AB31.0	Approved	[3]
Felodipine	DMOSW35	Hypertension	BA00-BA04	Approved	[74]
Fentanyl	DM8WAHT	Analgesia	MB40.8	Approved	[9]
Fesoterodine fumarate	DM13495	Overactive bladder	GC50.0	Approved	[75]
Fexofenadine	DM17ONX	Allergic rhinitis	CA08.0	Approved	[76]
Fluorouracil	DMUM7HZ	Adenocarcinoma	2D40	Approved	[9]
Fluoxetine	DM3PD2C	Bipolar depression		Approved	[77]
Flupentixol	DM0DJ9O	Schizophrenia	6A20	Approved	[10]
Fluphenazine	DMIT8LX	Psychotic disorder	6A20-6A25	Approved	[10]
Fluticasone propionate	DMRWLB2	Allergic asthma	CA23.0	Approved	[22]
Fluvastatin	DM4MDJY	Arteriosclerosis	BD40	Approved	[55]
Fluvoxamine	DMQTJSX	Depression	6A70-6A7Z	Approved	[10]
Folic Acid	DMEMBJC	Colorectal carcinoma		Approved	[78]
Fosamprenavir	DM4W9B3	Human immunodeficiency virus infection	1C62	Approved	[14]
Gatifloxacin	DMSL679	Acute gonococcal cervicitis		Approved	[79]
Gefitinib	DM15F0X	Colon adenocarcinoma		Approved	[80]
Gemcitabine	DMSE3I7	Anterior urethra cancer		Approved	[81]
Gepirone	DMGX5Q0	Major depressive disorder	6A70.3	Approved	[2]
Gilteritinib	DMTI0ZO	Acute myeloid leukaemia	2A60	Approved	[31]
Glecaprevir	DM31YVO	N. A.	N. A.	Approved	[14]
Glutathione	DMAHMT9	Human immunodeficiency virus infection	1C62	Approved	[82]
Gramicidin D	DMPT74U	Bacterial infection	1A00-1C4Z	Approved	[9]
Grepafloxacin	DMGLX0T	Chronic bronchitis	CA20.1	Approved	[9]
Guanabenz	DM5QWEL	High blood pressure	BA00	Approved	[55]
Guggulsterone	DMP7LK1	Osteoarthritis	FA00-FA05	Approved	[83]
Haloperidol	DM96SE0	Delirium		Approved	[10]
Hydrocortisone	DMGEMB7	Acne vulgaris	ED80	Approved	[22]
Hydroxyurea	DMOQVU9	Chronic myelogenous leukaemia	2A20.0	Approved	[9]
Ibrutinib	DMHZCPO	Mantle cell lymphoma	2A85.5	Approved	[84]
Idarubicin	DMM0XGL	Acute myelogenous leukaemia	2A41	Approved	[85]
Imatinib	DM7RJXL	Acute lymphoblastic leukaemia	2A85	Approved	[86]
Imipramine	DM2NUH3	Depression	6A70-6A7Z	Approved	[11]
Indacaterol	DMQJHR7	Chronic obstructive pulmonary disease	CA22	Approved	[31]
Indinavir	DM0T3YH	Human immunodeficiency virus infection	1C62	Approved	[87]
Indomethacin	DMSC4A7	Bursitis		Approved	[88]
Ingenol mebutate	DMK1CZJ	Actinic keratosis	EK90.0	Approved	[89]
Intedanib	DMSTA36	Colorectal cancer	2B91.Z	Approved	[90]
Irinotecan	DMP6SC2	Adenocarcinoma	2D40	Approved	[91]
Itraconazole	DMCR1MV	Aspergillosis	1F20	Approved	[9]
Ivacaftor	DMZC1HS	Cystic fibrosis	CA25	Approved	[92]
Ivermectin	DMDBX5F	Intestinal strongyloidiasis due to nematode parasite	1F6B	Approved	[93]
Ivosidenib	DM8S6T7	Acute myeloid leukaemia	2A60	Approved	[94]
Ixabepilone	DM2OZ3G	Breast cancer	2C60-2C65	Approved	[95]
Ketoconazole	DMPZI3Q	Blastomycosis	1F22	Approved	[9]
L-Tryptophan	DMIBH7M	Depression	6A70-6A7Z	Approved	[96]
Labetalol	DMK8U72	Hypertension	BA00-BA04	Approved	[2]
Lamotrigine	DM8SXYG	Bipolar disorder	6A60	Approved	[97]
Lapatinib	DM3BH1Y	Breast cancer	2C60-2C65	Approved	[14]
Lenalidomide	DM6Q7U4	Adult T-cell leukemia/lymphoma		Approved	[98]
Lenvatinib	DMB1IU4	Thyroid cancer	2D10	Approved	[99]
Levetiracetam	DMTGDN8	Epilepsy	8A60-8A68	Approved	[100]
Levodopa	DMN3E57	Parkinson disease	8A00.0	Approved	[2]
Levofloxacin	DMS60RB	Acute maxillary sinusitis		Approved	[9]
Levomepromazine	DMIKFEL	Bipolar disorder	6A60	Approved	[10]
Levomilnacipran	DMV26S8	Fibromyalgia	MG30.01	Approved	[101]
Lidocaine	DML4ZOT	Anaesthesia	9A78.6	Approved	[9]
Linagliptin	DMWFJTR	Non-insulin dependent diabetes	5A11	Approved	[14]
Loperamide	DMOJZQ9	Diarrhea	ME05.1	Approved	[102]
Lopinavir	DMITQS0	Human immunodeficiency virus infection	1C62	Approved	[103]
Loratadine	DMF3AN7	Allergy	4A80-4A85	Approved	[56]
Losartan	DM72JXH	Diabetic kidney disease	GB61.Z	Approved	[104]
Lovastatin	DM9OZWQ	Arteriosclerosis	BD40	Approved	[9]
Lovastatin acid	DMGCQ4E	N. A.	N. A.	Approved	[2]
Maraviroc	DMTL94F	Human immunodeficiency virus infection	1C62	Approved	[14]
Mefloquine	DMWT905	Malaria	1F40-1F45	Approved	[105]
Melphalan	DMOLNHF	Hematologic disease	3C0Z	Approved	[106]
Meperidine	DMX4GND	Pain	MG30-MG3Z	Approved	[107]
Mequitazine	DMAFBCY	Allergic rhinitis	CA08.0	Approved	[3]
Methadone	DMTW6IU	Advanced cancer	2A00-2F9Z	Approved	[108]
Methotrexate	DM2TEOL	Anterior urethra cancer		Approved	[9]
Methylprednisolone	DM4BDON	Acute adrenal insufficiency		Approved	[109]
Methysergide	DM1EF73	Migraine	8A80	Approved	[3]
Midazolam	DMXOELT	Agitation	6A70.3	Approved	[55]
Midostaurin	DMI6E0R	Acute myeloid leukaemia	2A60	Approved	[2]
Mitomycin	DMH0ZJE	Breast cancer	2C60-2C65	Approved	[110]
Mitoxantrone	DMM39BF	Acute myelogenous leukaemia	2A41	Approved	[9]
Morphine	DMRMS0L	Advanced cancer	2A00-2F9Z	Approved	[111]
Mycophenolate mofetil	DMPQAGE	Hepatosplenic T-cell lymphoma		Approved	[112]
Nadolol	DMW6GVL	Angina pectoris	BA40	Approved	[14]
Nalbuphine	DMOSQGU	Pain	MG30-MG3Z	Approved	[3]
Naloxegol	DML0B41	Opioid-induced constipation	DB32.1	Approved	[14]
Neostigmine	DM6T2J3	Myasthenia gravis	8C6Y	Approved	[15]
Nevirapine	DM6HX9B	Human immunodeficiency virus infection	1C62	Approved	[2]
Nicardipine	DMCDYW7	High blood pressure	BA00	Approved	[57]
Nifedipine	DMSVOZT	Angina pectoris	BA40	Approved	[9]
Nilotinib	DM7HXWT	Chronic myelogenous leukaemia	2A20.0	Approved	[31]
Nimodipine	DMQ0RKZ	Cerebral vasospasm	BA85.Z	Approved	[2]
Nisoldipine	DM7ISKJ	Hypertension	BA00-BA04	Approved	[9]
Nitrendipine	DM21C09	Hypertension	BA00-BA04	Approved	[9]
Nizatidine	DMGFV3Z	Acid-reflux disorder	DA22	Approved	[113]
Norfloxacin	DMIZ6W2	Acute gonococcal cervicitis		Approved	[2]
Olanzapine	DMPFN6Y	Bipolar depression		Approved	[10]
Olaparib	DM8QB1D	Ovarian cancer	2C73	Approved	[114]
Olmesartan medoxomil	DMWBHRY	High blood pressure	BA00	Approved	[31]
Olopatadine	DMKMWQG	Allergic conjunctivitis	9A60.02	Approved	[2]
Omadacycline	DMR2J95	Acute bacterial skin infection	1C41	Approved	[115]
Omeprazole	DM471KJ	Cystic fibrosis	CA25	Approved	[55]
Ondansetron	DMOTQ1I	Chemotherapy-induced nausea	MD90	Approved	[105]
Oseltamivir	DMGO72P	Influenza	1E30-1E32	Approved	[116]
Oxcarbazepine	DM5PU6O	Epilepsy	8A60-8A68	Approved	[117]
Paclitaxel	DMLB81S	Breast carcinoma		Approved	[118]
Palbociclib	DMD7L94	Breast cancer	2C60-2C65	Approved	[119]
Paliperidone	DM7NPJS	Psychotic disorder	6A20-6A25	Approved	[120]
Panobinostat	DM58WKG	Chronic graft versus host disease		Approved	[121]
Pantoprazole	DMSVOCZ	Gastrinoma	2C10.1	Approved	[55]
Paroxetine	DM5PVQE	Anxiety disorder	6B00-6B0Z	Approved	[15]
Pazopanib HCl	DM6U9CQ	Renal cell carcinoma	2C90	Approved	[122]
Pemirolast	DML97WV	Allergic conjunctivitis	9A60.02	Approved	[2]
Pentazocine	DM1XBHS	Pain	MG30-MG3Z	Approved	[9]
Perazine	DM2AOTZ	Psychotic disorder	6A20-6A25	Approved	[10]
Perphenazine	DMA4MRX	Schizophrenia	6A20	Approved	[10]
Phenobarbital	DMXZOCG	Cluster headache	8A81.0	Approved	[117]
Phenprocoumon	DMDO279	Myocardial infarction	BA41-BA43	Approved	[123]
Phenytoin	DMNOKBV	Epilepsy	8A60-8A68	Approved	[117]
Pibrentasvir	DM27BL1	N. A.	N. A.	Approved	[14]
Pimozide	DMW83TP	Schizophrenia	6A20	Approved	[2]
Pirarubicin	DMGTW1I	Breast cancer	2C60-2C65	Approved	[2]
Pirenzepine	DMP6M1N	Peptic ulcer	DA61	Approved	[3]
Pomalidomide	DMTGBAX	Plasma cell myeloma	2A83.1	Approved	[124]
Ponatinib	DMYGJQO	Acute lymphoblastic leukaemia	2A85	Approved	[125]
Posaconazole	DMUL5EW	Aspergillosis	1F20	Approved	[31]
Pravastatin	DM6A0X7	Adult acute monocytic leukemia		Approved	[14]
Prazosin	DMCD9YG	Benign prostatic hyperplasia	GA90	Approved	[126]
Prednisolone	DMQ8FR2	Acute adrenal insufficiency		Approved	[127]
Prednisone	DM2HG4X	Acute asthma	CA23	Approved	[24]
Progesterone	DMUY35B	Amenorrhea	GA20.0	Approved	[58]
Propafenone	DMPIBJK	Tachyarrhythmias	BC71	Approved	[9]
Propranolol	DM79NTF	Angina pectoris	BA40	Approved	[14]
Protriptyline	DMNHTZI	Depression	6A70-6A7Z	Approved	[3]
Quercetin	DM3NC4M	Obesity	5B81	Approved	[128]
Quetiapine	DM1N62C	Anorexia nervosa cachexia	6B80	Approved	[10]
Quinine	DMSWYF5	Malaria	1F40-1F45	Approved	[9]
R0-93877	DMM4U9G	Constipation	DD91.1	Approved	[129]
Raloxifene	DMDKF3M	Osteoporosis	FB83.0	Approved	[130]
Ramosetron	DMH7GN8	Diarrhea-predominant irritable bowel syndrome	DD91.01	Approved	[131]
Ranitidine	DM0GUSX	Gastric ulcer	DA60	Approved	[9]
Ranolazine	DM0C9IL	Acute coronary syndrome	BA41	Approved	[132]
Regorafenib	DMHSY1I	Gastrointestinal stromal tumour	2B5B	Approved	[133]
Relugolix	DMK7IWL	Prostate cancer	2C82.0	Approved	[31]
Reserpine	DM6VM38	Hypertension	BA00-BA04	Approved	[15]
Rifampin	DMA8J1G	Tuberculosis	1B10-1B1Z	Approved	[9]
Rifaximin	DMW1TV2	Bacterial infection	1A00-1C4Z	Approved	[134]
Riociguat	DMXBLMP	Chronic thromboembolic pulmonary hypertension		Approved	[135]
Risperidone	DMN6DXL	Bipolar I disorder		Approved	[136]
Ritonavir	DMU764S	Human immunodeficiency virus infection	1C62	Approved	[137]
Rivaroxaban	DMQMBZ1	Deep vein thrombosis	BD71	Approved	[138]
Romidepsin	DMT5GNL	Cutaneous T-cell lymphoma	2B01	Approved	[139]
Rosuvastatin	DMMIQ7G	Arteriosclerosis	BD40	Approved	[140]
S-licarbazepine	DMDIZCS	N. A.	N. A.	Approved	[69]
Saphris	DM5VP0F	N. A.	N. A.	Approved	[2]
Saquinavir	DMG814N	Human immunodeficiency virus infection	1C62	Approved	[141]
Saxagliptin	DMGXENV	Type-2 diabetes	5A11	Approved	[14]
Sertraline	DM0FB1J	Coronary heart disease	BA80.Z	Approved	[15]
SILODOSIN	DMJSBT6	Benign prostatic hyperplasia	GA90	Approved	[142]
Simeprevir	DMLUA9D	Chronic HCV-1 infection	1E51.1	Approved	[31]
Simvastatin	DM30SGU	Arteriosclerosis	BD40	Approved	[9]
Sirolimus	DMGW1ID	Advanced cancer	2A00-2F9Z	Approved	[143]
Sitagliptin	DMGDKXN	Cystic fibrosis	CA25	Approved	[14]
Sofosbuvir	DMQI86A	Hepatitis C	1E51	Approved	[144]
Sorafenib	DMS8IFC	Adenocarcinoma	2D40	Approved	[145]
Sparfloxacin	DMB4HCT	Bacterial infection	1A00-1C4Z	Approved	[9]
Sumatriptan	DMVYXR8	Cluster headache	8A81.0	Approved	[146]
Sunitinib	DMCBJSR	Acute undifferentiated leukemia		Approved	[147]
Sunitinib malate	DMN8E5D	N. A.	N. A.	Approved	[148]
Tacrine	DM51FY6	Alzheimer disease	8A20	Approved	[149]
Tacrolimus	DMZ7XNQ	Graft-versus-host disease	4B24	Approved	[9]
Tadalafil	DMJZHT1	Benign prostatic hyperplasia	GA90	Approved	[150]
Talazoparib	DM1KS78	Breast cancer	2C60-2C65	Approved	[151]
Tamoxifen	DMLB0EZ	Breast cancer	2C60-2C65	Approved	[9]
Telaprevir	DMMRV29	Hepatitis C virus infection	1E51.1	Approved	[28]
Telithromycin	DMZ4P3A	Bacterial infection	1A00-1C4Z	Approved	[152]
Temsirolimus	DMS104F	Renal cell carcinoma	2C90	Approved	[153]
Teniposide	DMLW57T	Acute lymphoblastic leukaemia	2A85	Approved	[9]
Tenofovir	DM1IS6U	Chronic hepatitis B virus infection		Approved	[31]
Tenofovir alafenamide	DMTQF4A	Hiv infectious disease		Approved	[154]
Tenoxicam	DMVAZP9	Rheumatoid arthritis	FA20	Approved	[2]
Testosterone	DM7HUNW	Hot flushes	GA30	Approved	[55]
Tetracycline	DMZA017	Acne vulgaris	ED80	Approved	[9]
Thiamphenicol	DMDRKH2	Bacterial infection	1A00-1C4Z	Approved	[41]
Thioridazine	DM35M8J	Schizophrenia	6A20	Approved	[15]
Timolol	DM3NXRU	High blood pressure	BA00	Approved	[36]
Tolvaptan	DMIWFRL	Autosomal dominant polycystic kidney disease	GB81	Approved	[155]
Topiramate	DM82Z30	Alcohol dependence	6C40.2	Approved	[156]
Topotecan	DMP6G8T	Central nervous system neoplasm		Approved	[157]
Toremifene	DMQYUWG	Breast cancer	2C60-2C65	Approved	[45]
Tramadol	DMRQD04	Osteoarthritis	FA00-FA05	Approved	[158]
Tretinoin	DM49DUI	Acne vulgaris	ED80	Approved	[12]
Trifluoperazine	DMKBYWI	Anxiety		Approved	[9]
Triflupromazine	DMKFQJP	Nausea	MD90	Approved	[2]
Trimethoprim	DMM7CHK	Acute otitis media	AB00	Approved	[15]
Triprolidine	DM7SWIA	Allergic rhinitis	CA08.0	Approved	[159]
Trospium chloride	DM32XZT	Discovery agent	N.A.	Approved	[160]
Vecuronium	DMP0UK2	Spasm	MB47.3	Approved	[105]
Velpatasvir	DMGF8ZQ	N. A.	N. A.	Approved	[14]
Vemurafenib	DM62UG5	Melanoma	2C30	Approved	[161]
Venetoclax	DM8I94Y	Chronic lymphocytic leukaemia	2A82.0	Approved	[162]
Verapamil	DMA7PEW	Angina pectoris	BA40	Approved	[163]
Vibegron	DMFR201	Overactive bladder	GC50.0	Approved	[31]
Vildagliptin	DMYN59P	Type-2 diabetes	5A11	Approved	[164]
Vinblastine	DM5TVS3	Advanced cancer	2A00-2F9Z	Approved	[165]
Vincristine	DMINOX3	Acute lymphoblastic leukaemia	2A85	Approved	[166]
Vindesine	DMVR628	Acute lymphoblastic leukaemia	2A85	Approved	[2]
Vinorelbine	DMVXFYE	Advanced cancer	2A00-2F9Z	Approved	[167]
Voxilaprevir	DMAI83D	N. A.	N. A.	Approved	[14]
VRX496	DMIO4V5	Acquired immune deficiency syndrome	1C62.3	Approved	[168]
Y-25130	DMDPM7R	Nausea and vomiting	MD90	Approved	[2]
Zidovudine	DM4KI7O	Human immunodeficiency virus infection	1C62	Approved	[1]
Ziprasidone	DMM58JY	Bipolar disorder	6A60	Approved	[15]
Zolmitriptan	DM1IB4Q	Migraine	8A80	Approved	[15]
Beclomethasone dipropionate	DM5NW1E	Allergic rhinitis	CA08.0	Phase 4	[22]
Berberine	DMC5Q8X	N. A.	N. A.	Phase 4	[169]
Dihydrotestosterone	DM3S8XC	Prostate hyperplasia	GA90	Phase 4	[170]
Ebastine	DMH21D9	N. A.	N. A.	Phase 4	[2]
Guanfacine	DMPN5IH	Attention deficit hyperactivity disorder	6A05.Z	Phase 4	[171]
Ombitasvir	DMQIMTK	Hepatitis C	1E51	Phase 4	[14]
Tenofovir disoproxil	DM62IPN	N. A.	N. A.	Phase 4	[2]

29 Clinical Trial Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
ABT-263	DMNE56X	Myelofibrosis	2A20.2	Phase 3	[172]
Asimadoline	DMND3AB	Diarrhea-predominant irritable bowel syndrome	DD91.01	Phase 3	[9]
Crocin	DM5F24X	N. A.	N. A.	Phase 3	[12]
Curcumin	DMQPH29	Solid tumour/cancer	2A00-2F9Z	Phase 3	[9]
MELAGATRAN	DM4W8RE	N. A.	N. A.	Phase 3	[2]
Morphine-6-glucuronide	DMPVW6H	Pain	MG30-MG3Z	Phase 3	[2]
Pazufloxacin	DMHXTAQ	Conjunctivitis	9A60	Phase 3	[173]
Simvastatin acid	DM18QHT	N. A.	N. A.	Phase 3	[174]
Sitafloxacin	DMTV5XC	Escherichia coli infection	1A03	Phase 2/3	[2]
(Z)-endoxifen	DMGDOS2	N. A.	N. A.	Phase 2	[175]
Afimoxifene	DMFORDT	Breast cancer	2C60-2C65	Phase 2	[45]
Arverapamil	DML27AE	Irritable bowel syndrome	DD91.0	Phase 2	[176]
Bisantrene	DMW76V0	N. A.	N. A.	Phase 2	[9]
BMS 650032	DMQI43G	Hepatitis C virus infection	1E51.1	Phase 2	[31]
CKD602	DMW9F1G	Solid tumour/cancer	2A00-2F9Z	Phase 2	[2]
CP-122721	DMSWLM5	Major depressive disorder	6A70.3	Phase 2	[177]
Dolastatin 10	DM0QDC9	N. A.	N. A.	Phase 2	[178]
Fucoxanthin	DMPQFTA	Metabolic syndrome x	5C50-5D2Z	Phase 2	[12]
Gallopamil	DMXBR27	Asthma	CA23	Phase 2	[2]
GS-5885	DMSL3DX	Hepatitis C virus infection	1E51.1	Phase 2	[14]
ONO-6126	DMRT28X	Chronic obstructive pulmonary disease	CA22	Phase 2	[179]
Paritaprevir	DM4N7BT	Hepatitis C	1E51	Phase 2	[14]
R-roscovitine	DMSH108	Non-small-cell lung cancer	2C25.Y	Phase 2	[180]
ABT-333	DM7TOWX	Hepatitis C virus infection	1E51.1	Phase 1	[14]
Genz 644282	DMTGN0U	N. A.	N. A.	Phase 1	[181]
Mibefradil	DMU9VDS	Glioblastoma multiforme	2A00.0	Phase 1	[2]
NARINGENIN	DMHAZLM	N. A.	N. A.	Phase 1	[128]
Norbuprenorphine	DM2ILSJ	N. A.	N. A.	Phase 1	[182]
Sphingosine-1-phosphate	DMJCQKA	Acne vulgaris	ED80	Phase 1	[183]

20 Discontinued Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alprenolol	DMYJ8Z3	Hypertension	BA00-BA04	Withdrawn from market	[55]
Astemizole	DM2HN6Q	Allergic rhinitis	CA08.0	Withdrawn from market	[15]
Isoxicam	DMMS2J5	Osteoarthritis	FA00-FA05	Withdrawn from market	[2]
Roxithromycin	DMVMIK2	Bacterial infection	1A00-1C4Z	Withdrawn from market	[152]
Terfenadine	DM4KLPT	Allergy	4A80-4A85	Withdrawn from market	[9]
Ximelagatran	DMABRJL	Coagulation defect	3B10.0	Withdrawn from market	[2]
Flesinoxan	DMOIP7R	Anxiety disorder	6B00-6B0Z	Discontinued in Phase 3	[184]
Valspodar	DMXRU9M	Acute myeloid leukaemia	2A60	Discontinued in Phase 3	[9]
DE-081	DM3AVO1	Conjunctivitis	9A60	Discontinued in Phase 2	[185]
Dexniguldipine	DMLZIT2	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[179]
Droloxifene	DM9JPUD	Breast cancer	2C60-2C65	Discontinued in Phase 2	[2]
Radafaxine	DMARQE0	Major depressive disorder	6A70.3	Discontinued in Phase 2	[32]
S-9788	DMER3I9	Solid tumour/cancer	2A00-2F9Z	Discontinued in Phase 2	[2]
Tolafentrine	DMEROU4	Chronic obstructive pulmonary disease	CA22	Discontinued in Phase 2	[55]
PAFENOLOL	DM6LQGO	Hypertension	BA00-BA04	Discontinued in Phase 1	[2]
Rhodamine-123	DMQAK6T	Prostate cancer	2C82.0	Discontinued in Phase 1	[57]
ABT-737	DML0DBV	N. A.	N. A.	Terminated	[172]
Bisbenzimide (Hoechst 33258)	DMKRBL2	Solid tumour/cancer	2A00-2F9Z	Terminated	[9]
Calphostin C	DM9X2D0	N. A.	N. A.	Terminated	[2]
NIGULDIPINE	DMSPWMF	N. A.	N. A.	Terminated	[2]

15 Preclinical Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Abamectin B1A	DMRSATG	N. A.	N. A.	Preclinical	[186]
BMS-3870032	DMCWIBU	N. A.	N. A.	Preclinical	[2]
Bouvardin	DM5O3HC	N. A.	N. A.	Preclinical	[179]
Bunitrolol	DMT4532	N. A.	N. A.	Preclinical	[187]
Cephaeline	DM1ZFCS	N. A.	N. A.	Preclinical	[179]
Coelenterazine	DMG3BE1	N. A.	N. A.	Preclinical	[188]
Desmethylsertraline	DM2I76R	N. A.	N. A.	Preclinical	[32]
Epothilone A	DMX2FZS	N. A.	N. A.	Preclinical	[2]
Metildigoxin	DMDPV82	N. A.	N. A.	Preclinical	[31]
Metkephamid	DMDU8KC	N. A.	N. A.	Preclinical	[179]
MG-132	DMKA2YS	N. A.	N. A.	Preclinical	[189]
N-desethyl sunitinib	DM5ATJ0	N. A.	N. A.	Preclinical	[190]
Nonactin	DMKF2H0	N. A.	N. A.	Preclinical	[51]
Puromycin	DMDKLB5	N. A.	N. A.	Preclinical	[191]
Selamectin	DM5LU3N	N. A.	N. A.	Preclinical	[186]

22 Investigative Drug(s) Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
(11-BETA)-11,21-DIHYDROXY-PREGN-4-ENE-3,20-DIONE	DMTPQ84	Discovery agent	N.A.	Investigative	[45]
azidopine	DMD0LCA	Discovery agent	N.A.	Investigative	[9]
Bcecf-Am	DMPG1LJ	N. A.	N. A.	Investigative	[9]
biotin	DMKMCE1	Discovery agent	N.A.	Investigative	[192]
Cholesterol	DMR3J6S	Discovery agent	N.A.	Investigative	[193]
cycloheximide	DMGDA3C	Discovery agent	N.A.	Investigative	[12]
FLUPENTIXOLE	DMELB5S	Discovery agent	N.A.	Investigative	[9]
G418	DMKTJBU	Discovery agent	N.A.	Investigative	[191]
GNF-PF-5411	DMZNAEQ	Discovery agent	N.A.	Investigative	[2]
Leupeptin	DMU075F	Malaria	1F40-1F45	Investigative	[9]
Nafoxidine	DM0FROP	Discovery agent	N.A.	Investigative	[45]
Nogalamycin	DM50TCG	Discovery agent	N.A.	Investigative	[179]
Okadaic acid	DM47CO1	Discovery agent	N.A.	Investigative	[179]
paraquat	DMR8O3X	Discovery agent	N.A.	Investigative	[9]
prostaglandin A2	DMWC4X8	Discovery agent	N.A.	Investigative	[194]
Staurosporine	DM0E9BR	Discovery agent	N.A.	Investigative	[2]
Substance P	DMQ6W4I	Discovery agent	N.A.	Investigative	[196]
talinolol	DMRTD16	Discovery agent	N.A.	Investigative	[197]
Tiapamil	DMWSI0H	Cardiovascular disease	BA00-BE2Z	Investigative	[9]
Tyrphostin ag-1478	DM87ZIH	Discovery agent	N.A.	Investigative	[198]
Valinomycin	DMW4TYV	N. A.	N. A.	Investigative	[57]
[3H]spiperone	DMWHEV8	Discovery agent	N.A.	Investigative	[2]

1 Investigative Agents Transported by This DTP

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Silvestrol	DM5JKNF	Middle East Respiratory Syndrome (MERS)	1D64	Investigative	[195]

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