1 |
ClinicalTrials.gov (NCT01083524) Dichloroacetate (DCA) for the Treatment of Pulmonary Arterial Hypertension. U.S. National Institutes of Health.
|
2 |
ClinicalTrials.gov (NCT04308681) A Multicenter, Randomized, Double-blind, Placebo-controlled, Phase 2 Study of the Efficacy and the Safety and Tolerability of BMS-986278 in Participants With Pulmonary Fibrosis. U.S.National Institutes of Health.
|
3 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 771).
|
4 |
Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800034106)
|
5 |
ClinicalTrials.gov (NCT05354453) Safety, Tolerability, and Pharmacokinetics of Single Rising Oral Doses of BI 1839100 in Healthy Male Subjects (Single-blind, Randomised, Placebo-controlled, Parallel Group Design). U.S.National Institutes of Health.
|
6 |
ClinicalTrials.gov (NCT04550195) A Double-Blind, Placebo-Controlled, Randomized, Single and Multiple Ascending Dose Study of the Safety and Tolerability, and Pharmacokinetics (Including Food Effect, pH Effect and Japanese Bridging Study) of BMS-986337 Following Oral Administration in Healthy Participants. U.S.National Institutes of Health.
|
7 |
Drugs and Targets in Fibrosis. Front Pharmacol. 2017 Nov 23;8:855.
|
8 |
Targeting metabolic dysregulation for fibrosis therapy. Nat Rev Drug Discov. 2020 Jan;19(1):57-75.
|
9 |
Targeting of alphav integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013 Dec;19(12):1617-24.
|
10 |
Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nat Rev Drug Discov. 2017 Sep;16(9):787-810.
|
11 |
PI3K-Akt-mTOR/PFKFB3 pathway mediated lung fibroblast aerobic glycolysis and collagen synthesis in lipopolysaccharide-induced pulmonary fibrosis. Lab Invest. 2020 Jun;100(6):801-811.
|
12 |
The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
|
13 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1788).
|
14 |
Salvia officinalis attenuates bleomycin-induced oxidative stress and lung fibrosis in rats.Nutr Cancer. 2020;72(7):1135-1145. doi: 10.1080/01635581.2019.1675724. Epub 2019 Oct 12.
|
15 |
Caveolin-1-derived peptide limits development of pulmonary fibrosis.Sci Transl Med. 2019 Dec 11;11(522):eaat2848. doi: 10.1126/scitranslmed.aat2848.
|
16 |
Relationship between eosinophilia and levels of chemokines (CCL5 and CCL11) and IL-5 in bronchoalveolar lavage fluid of patients with mustard gas-induced pulmonary fibrosis.J Clin Immunol. 2007 Nov;27(6):605-12. doi: 10.1007/s10875-007-9114-y. Epub 2007 Jul 10.
|
17 |
Targeting Degradation of the Transcription Factor C/EBP Reduces Lung Fibrosis by Restoring Activity of the Ubiquitin-Editing Enzyme A20 in Macrophages.Immunity. 2019 Sep 17;51(3):522-534.e7. doi: 10.1016/j.immuni.2019.06.014. Epub 2019 Aug 27.
|
18 |
Therapeutic strategies to correct proteostasis-imbalance in chronic obstructive lung diseases.Curr Mol Med. 2012 Aug;12(7):807-14. doi: 10.2174/156652412801318809.
|
19 |
Characterization of CD28(null) T cells in idiopathic pulmonary fibrosis.Mucosal Immunol. 2019 Jan;12(1):212-222. doi: 10.1038/s41385-018-0082-8. Epub 2018 Oct 12.
|
20 |
The fibrogenic actions of the coagulant and plasminogen activation systems in pulmonary fibrosis.Int J Biochem Cell Biol. 2018 Apr;97:108-117. doi: 10.1016/j.biocel.2018.02.016. Epub 2018 Feb 21.
|
21 |
Quercetin Enhances Ligand-induced Apoptosis in Senescent Idiopathic Pulmonary Fibrosis Fibroblasts and Reduces Lung Fibrosis In Vivo.Am J Respir Cell Mol Biol. 2019 Jan;60(1):28-40. doi: 10.1165/rcmb.2017-0289OC.
|
22 |
Fibroblast growth factor-1 attenuates TGF-1-induced lung fibrosis.J Pathol. 2016 Oct;240(2):197-210. doi: 10.1002/path.4768.
|
23 |
Nrf2 antioxidant pathway suppresses Numb-mediated epithelial-mesenchymal transition during pulmonary fibrosis.Cell Death Dis. 2018 Jan 23;9(2):83. doi: 10.1038/s41419-017-0198-x.
|
24 |
Acute Lung Injury: IL-17A-Mediated Inflammatory Pathway and Its Regulation by Curcumin.Inflammation. 2019 Aug;42(4):1160-1169. doi: 10.1007/s10753-019-01010-4.
|
25 |
Biomarkers of skin and lung fibrosis in systemic sclerosis.Expert Rev Clin Immunol. 2019 Nov;15(11):1215-1223. doi: 10.1080/1744666X.2020.1670062. Epub 2019 Sep 30.
|
26 |
The status of pulmonary fibrosis in systemic sclerosis is associated with IRF5, STAT4, IRAK1, and CTGF polymorphisms.Rheumatol Int. 2017 Aug;37(8):1303-1310. doi: 10.1007/s00296-017-3722-5. Epub 2017 Apr 22.
|
27 |
Repression of TSC1/TSC2 mediated by MeCP2 regulates human embryo lung fibroblast cell differentiation and proliferation.Int J Biol Macromol. 2017 Mar;96:578-588. doi: 10.1016/j.ijbiomac.2016.12.062. Epub 2016 Dec 29.
|
28 |
Interleukin-7 and transforming growth factor-beta play counter-regulatory roles in protein kinase C-delta-dependent control of fibroblast collagen synthesis in pulmonary fibrosis.J Biol Chem. 2004 Jul 2;279(27):28315-9. doi: 10.1074/jbc.C400115200. Epub 2004 May 7.
|
29 |
Anti-citrullinated peptides antibodies in systemic sclerosis: Meta-analysis of frequency and meaning.Joint Bone Spine. 2018 Mar;85(2):147-153. doi: 10.1016/j.jbspin.2017.11.006. Epub 2017 Nov 26.
|
30 |
A STAT6 Inhibitor AS1517499 Reduces Preventive Effects of Apoptotic Cell Instillation on Bleomycin-Induced Lung Fibrosis by Suppressing PPAR.Cell Physiol Biochem. 2018;45(5):1863-1877. doi: 10.1159/000487877. Epub 2018 Feb 28.
|
31 |
Transforming growth factor-{beta} gene polymorphisms in different phenotypes of sarcoidosis.Eur Respir J. 2011 Jul;38(1):169-75. doi: 10.1183/09031936.00120410. Epub 2010 Dec 9.
|
32 |
miR-30a as Potential Therapeutics by Targeting TET1 through Regulation of Drp-1 Promoter Hydroxymethylation in Idiopathic Pulmonary Fibrosis. Int J Mol Sci. 2017 Mar 15;18(3). pii: E633.
|
33 |
HIF1A up-regulates the ADORA2B receptor on alternatively activated macrophages and contributes to pulmonary fibrosis.FASEB J. 2017 Nov;31(11):4745-4758. doi: 10.1096/fj.201700219R. Epub 2017 Jul 12.
|
34 |
miR-627/HMGB1/NF-B regulatory loop modulates TGF-1-induced pulmonary fibrosis.J Cell Biochem. 2019 Mar;120(3):2983-2993. doi: 10.1002/jcb.27038. Epub 2018 Dec 9.
|
35 |
Inhibitory effects of pirfenidone on fibroblast to myofibroblast transition in rheumatoid arthritis-associated interstitial lung disease via the downregulation of activating transcription factor 3 (ATF3).Int Immunopharmacol. 2019 Sep;74:105700. doi: 10.1016/j.intimp.2019.105700. Epub 2019 Jun 19.
|
36 |
Pirfenidone attenuates bleomycin-induced pulmonary fibrosis in mice by regulating Nrf2/Bach1 equilibrium.BMC Pulm Med. 2017 Apr 18;17(1):63. doi: 10.1186/s12890-017-0405-7.
|
37 |
Role of Eotaxin-1 (CCL11) and CC chemokine receptor 3 (CCR3) in bleomycin-induced lung injury and fibrosis.Am J Pathol. 2005 Dec;167(6):1485-96. doi: 10.1016/S0002-9440(10)61235-7.
|
38 |
Elevated expression of TARC (CCL17) and MDC (CCL22) in models of cigarette smoke-induced pulmonary inflammation.Biochem Biophys Res Commun. 2005 Aug 19;334(1):254-62. doi: 10.1016/j.bbrc.2005.06.084.
|
39 |
Cadherin-11 contributes to liver fibrosis induced by carbon tetrachloride.PLoS One. 2019 Jul 3;14(7):e0218971. doi: 10.1371/journal.pone.0218971. eCollection 2019.
|
40 |
Pirfenidone activates cannabinoid receptor 2 in a mouse model of bleomycin-induced pulmonary fibrosis.Exp Ther Med. 2019 Dec;18(6):4241-4248. doi: 10.3892/etm.2019.8045. Epub 2019 Sep 25.
|
41 |
Important roles for macrophage colony-stimulating factor, CC chemokine ligand 2, and mononuclear phagocytes in the pathogenesis of pulmonary fibrosis.Am J Respir Crit Care Med. 2007 Jul 1;176(1):78-89. doi: 10.1164/rccm.200609-1279OC. Epub 2007 Apr 12.
|
42 |
Pretreatment with G-CSF Could Enhance the Antifibrotic Effect of BM-MSCs on Pulmonary Fibrosis.Stem Cells Int. 2019 Jan 3;2019:1726743. doi: 10.1155/2019/1726743. eCollection 2019.
|
43 |
Neotuberostemonine inhibits the differentiation of lung fibroblasts into myofibroblasts in mice by regulating HIF-1 signaling.Acta Pharmacol Sin. 2018 Sep;39(9):1501-1512. doi: 10.1038/aps.2017.202. Epub 2018 Apr 12.
|
44 |
MiR-34b-5p knockdown attenuates bleomycin-induced pulmonary fibrosis by targeting tissue inhibitor of metalloproteinase 3 (TIMP3).Eur Rev Med Pharmacol Sci. 2019 Mar;23(5):2273-2279. doi: 10.26355/eurrev_201903_17276.
|
45 |
(18)F-AzaFol for Detection of Folate Receptor- Positive Macrophages in Experimental Interstitial Lung Disease-A Proof-of-Concept Study.Front Immunol. 2019 Nov 22;10:2724. doi: 10.3389/fimmu.2019.02724. eCollection 2019.
|
46 |
Knockdown of Fstl1 attenuates hepatic stellate cell activation through the TGF?/Smad3 signaling pathway.Mol Med Rep. 2017 Nov;16(5):7119-7123. doi: 10.3892/mmr.2017.7445. Epub 2017 Sep 8.
|
47 |
Redox Regulation via Glutaredoxin-1 and Protein S-Glutathionylation.Antioxid Redox Signal. 2020 Apr 1;32(10):677-700. doi: 10.1089/ars.2019.7963. Epub 2020 Jan 23.
|
48 |
HDAC8 inhibition ameliorates pulmonary fibrosis.Am J Physiol Lung Cell Mol Physiol. 2019 Jan 1;316(1):L175-L186. doi: 10.1152/ajplung.00551.2017. Epub 2018 Oct 25.
|
49 |
IL1RN genetic variations and risk of IPF: a meta-analysis and mRNA expression study.Immunogenetics. 2012 May;64(5):371-7. doi: 10.1007/s00251-012-0604-6. Epub 2012 Feb 10.
|
50 |
Reduced Ets Domain-containing Protein Elk1 Promotes Pulmonary Fibrosis via Increased Integrin v6 Expression.J Biol Chem. 2016 Apr 29;291(18):9540-53. doi: 10.1074/jbc.M115.692368. Epub 2016 Feb 9.
|
51 |
Prevention and treatment of bleomycin-induced pulmonary fibrosis with the lactate dehydrogenase inhibitor gossypol.PLoS One. 2018 May 24;13(5):e0197936. doi: 10.1371/journal.pone.0197936. eCollection 2018.
|
52 |
BLT1 Mediates Bleomycin-Induced Lung Fibrosis Independently of Neutrophils and CD4+ T Cells.J Immunol. 2017 Feb 15;198(4):1673-1684. doi: 10.4049/jimmunol.1600465. Epub 2017 Jan 11.
|
53 |
Specific Features of Fibrotic Lung Fibroblasts Highly Sensitive to Fibrotic Processes Mediated via TGF--ERK5 Interaction.Cell Physiol Biochem. 2019;52(4):822-837. doi: 10.33594/000000057.
|
54 |
Mitogen-activated Protein Kinase-activated Protein Kinase 2 Inhibition Attenuates Fibroblast Invasion and Severe Lung Fibrosis.Am J Respir Cell Mol Biol. 2019 Jan;60(1):41-48. doi: 10.1165/rcmb.2018-0033OC.
|
55 |
Matrix Metalloproteinases-7 and Kidney Fibrosis.Front Physiol. 2017 Feb 10;8:21. doi: 10.3389/fphys.2017.00021. eCollection 2017.
|
56 |
The Role of the Mammalian Target of Rapamycin (mTOR) in Pulmonary Fibrosis.Int J Mol Sci. 2018 Mar 8;19(3):778. doi: 10.3390/ijms19030778.
|
57 |
Invivo effects of the NLRP1/NLRP3 inflammasome pathway on latent respiratory virus infection.Int J Mol Med. 2018 Jun;41(6):3620-3628. doi: 10.3892/ijmm.2018.3521. Epub 2018 Feb 28.
|
58 |
NOX4 modulates macrophage phenotype and mitochondrial biogenesis in asbestosis.JCI Insight. 2019 Aug 22;4(16):e126551. doi: 10.1172/jci.insight.126551.
|
59 |
Oncostatin M-Preconditioned Mesenchymal Stem Cells Alleviate Bleomycin-Induced Pulmonary Fibrosis Through Paracrine Effects of the Hepatocyte Growth Factor.Stem Cells Transl Med. 2017 Mar;6(3):1006-1017. doi: 10.5966/sctm.2016-0054. Epub 2016 Oct 18.
|
60 |
Effects of PARP-1 Deficiency and Histamine H(4) Receptor Inhibition in an Inflammatory Model of Lung Fibrosis in Mice.Front Pharmacol. 2019 May 16;10:525. doi: 10.3389/fphar.2019.00525. eCollection 2019.
|
61 |
Therapeutic effects of obeticholic acid (OCA) treatment in a bleomycin-induced pulmonary fibrosis rat model.J Endocrinol Invest. 2019 Mar;42(3):283-294. doi: 10.1007/s40618-018-0913-1. Epub 2018 Jun 19.
|
62 |
Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach.Front Physiol. 2018 Jun 19;9:587. doi: 10.3389/fphys.2018.00587. eCollection 2018.
|
63 |
Reduced supply of monocyte-derived macrophages leads to a transition from nodular to diffuse lesions and tissue cell activation in silica-induced pulmonary fibrosis in mice.Am J Pathol. 2015 Nov;185(11):2923-38. doi: 10.1016/j.ajpath.2015.07.013. Epub 2015 Oct 9.
|
64 |
The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.Am J Respir Cell Mol Biol. 2018 Apr;58(4):471-481. doi: 10.1165/rcmb.2017-0075OC.
|
65 |
Syndecan-2 Attenuates Radiation-induced Pulmonary Fibrosis and Inhibits Fibroblast Activation by Regulating PI3K/Akt/ROCK Pathway via CD148.Am J Respir Cell Mol Biol. 2018 Feb;58(2):208-215. doi: 10.1165/rcmb.2017-0088OC.
|
66 |
Overexpression of SERPIN B3 promotes epithelial proliferation and lung fibrosis in mice.Lab Invest. 2011 Jun;91(6):945-54. doi: 10.1038/labinvest.2011.1. Epub 2011 Mar 14.
|
67 |
Sirtuin 6 inhibits MWCNTs-induced epithelial-mesenchymal transition in human bronchial epithelial cells via inactivating TGF-1/Smad2 signaling pathway.Toxicol Appl Pharmacol. 2019 Jul 1;374:1-10. doi: 10.1016/j.taap.2019.04.013. Epub 2019 Apr 18.
|
68 |
SET9-Mediated Regulation of TGF- Signaling Links Protein Methylation to Pulmonary Fibrosis.Cell Rep. 2016 Jun 21;15(12):2733-44. doi: 10.1016/j.celrep.2016.05.051. Epub 2016 Jun 9.
|
69 |
Pulmonary Fibrosis in Hermansky-Pudlak Syndrome.Ann Am Thorac Soc. 2016 Oct;13(10):1839-1846. doi: 10.1513/AnnalsATS.201603-186FR.
|
70 |
Roles of high-mobility group box 1 and thrombin in murine pulmonary fibrosis and the therapeutic potential of thrombomodulin.Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L473-L483. doi: 10.1152/ajplung.00287.2017. Epub 2017 Dec 6.
|
71 |
Role of bone marrow mesenchymal stem cells in the development of PQinduced pulmonary fibrosis.Mol Med Rep. 2019 Apr;19(4):3283-3290. doi: 10.3892/mmr.2019.9976. Epub 2019 Feb 20.
|
72 |
Tumor necrosis factor family member LIGHT acts with IL-1 and TGF- to promote airway remodeling during rhinovirus infection.Allergy. 2018 Jul;73(7):1415-1424. doi: 10.1111/all.13390. Epub 2018 Mar 1.
|
73 |
A pneumocyte-macrophage paracrine lipid axis drives the lung toward fibrosis.Am J Respir Cell Mol Biol. 2015 Jul;53(1):74-86. doi: 10.1165/rcmb.2014-0343OC.
|
74 |
Interaction of N-acetyl-seryl-aspartyl-lysyl-proline with the angiotensin-converting enzyme2-angiotensin-(1-7)-Mas axis attenuates pulmonary fibrosis in silicotic rats.Exp Physiol. 2019 Oct;104(10):1562-1574. doi: 10.1113/EP087515. Epub 2019 Aug 13.
|
75 |
The Role of Mitochondrial DNA in Mediating Alveolar Epithelial Cell Apoptosis and Pulmonary Fibrosis.Int J Mol Sci. 2015 Sep 7;16(9):21486-519. doi: 10.3390/ijms160921486.
|
76 |
ADAM33 gene polymorphisms are associated with the risk of idiopathic pulmonary fibrosis.Lung. 2014 Aug;192(4):525-32. doi: 10.1007/s00408-014-9578-5. Epub 2014 Apr 13.
|
77 |
Adiponectin attenuates lung fibroblasts activation and pulmonary fibrosis induced by paraquat. PLoS One. 2015 May 6;10(5):e0125169. doi: 10.1371/journal.pone.0125169. eCollection 2015.
|
78 |
Autophagy Attenuates Angiotensin II-Induced Pulmonary Fibrosis by Inhibiting Redox Imbalance-Mediated NOD-Like Receptor Family Pyrin Domain Containing 3 Inflammasome Activation.Antioxid Redox Signal. 2019 Feb 1;30(4):520-541. doi: 10.1089/ars.2017.7261. Epub 2018 May 7.
|
79 |
Effect of preventive or therapeutic treatment with angiotensin 1-7 in a model of bleomycin-induced lung fibrosis in mice.J Leukoc Biol. 2019 Sep;106(3):677-686. doi: 10.1002/JLB.MA1218-490RR. Epub 2019 Jun 30.
|
80 |
Identification of annexin 1 as a novel autoantigen in acute exacerbation of idiopathic pulmonary fibrosis.J Immunol. 2008 Jul 1;181(1):756-67. doi: 10.4049/jimmunol.181.1.756.
|
81 |
Amine oxidase activity regulates the development of pulmonary fibrosis.FASEB J. 2017 Jun;31(6):2477-2491. doi: 10.1096/fj.201600935R. Epub 2017 Mar 1.
|
82 |
The immunopathology of lung fibrosis: amphiregulin-producing pathogenic memory T helper-2 cells control the airway fibrotic responses by inducing eosinophils to secrete osteopontin.Semin Immunopathol. 2019 May;41(3):339-348. doi: 10.1007/s00281-019-00735-6. Epub 2019 Apr 9.
|
83 |
Anti-fibrotic effects of bone morphogenetic protein-7-modified bone marrow mesenchymal stem cells on silica-induced pulmonary fibrosis.Exp Mol Pathol. 2017 Feb;102(1):70-77. doi: 10.1016/j.yexmp.2016.12.010. Epub 2017 Jan 4.
|
84 |
Macrophage bone morphogenic protein receptor 2 depletion in idiopathic pulmonary fibrosis and Group III pulmonary hypertension.Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L238-54. doi: 10.1152/ajplung.00142.2016. Epub 2016 Jun 17.
|
85 |
Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.FASEB J. 2016 Jun;30(6):2336-50. doi: 10.1096/fj.201500044. Epub 2016 Mar 8.
|
86 |
Calcitonin gene-related peptide (CGRP) as hazard marker for lung injury induced by dusts.Inhal Toxicol. 2007 Mar;19(3):283-9. doi: 10.1080/08958370601069364.
|
87 |
Intranasal Curcumin Inhibits Pulmonary Fibrosis by Modulating Matrix Metalloproteinase-9 (MMP-9) in Ovalbumin-Induced Chronic Asthma.Inflammation. 2017 Feb;40(1):248-258. doi: 10.1007/s10753-016-0475-3.
|
88 |
Alternatively activated alveolar macrophages in pulmonary fibrosis-mediator production and intracellular signal transduction.Clin Immunol. 2010 Oct;137(1):89-101. doi: 10.1016/j.clim.2010.06.017. Epub 2010 Jul 31.
|
89 |
Elevated levels of MCP-1, MIP-alpha and MIP-1 beta in the bronchoalveolar lavage (BAL) fluid of patients with mustard gas-induced pulmonary fibrosis.Toxicology. 2007 Oct 30;240(1-2):60-9. doi: 10.1016/j.tox.2007.07.014. Epub 2007 Aug 1.
|
90 |
Palmitic Acid-Rich High-Fat Diet Exacerbates Experimental Pulmonary Fibrosis by Modulating Endoplasmic Reticulum Stress.Am J Respir Cell Mol Biol. 2019 Dec;61(6):737-746. doi: 10.1165/rcmb.2018-0324OC.
|
91 |
NLRP3 Inflammasome Activation Contributes to Mechanical Stretch-Induced Endothelial-Mesenchymal Transition and Pulmonary Fibrosis.Crit Care Med. 2018 Jan;46(1):e49-e58. doi: 10.1097/CCM.0000000000002799.
|
92 |
Taurine ameliorates particulate matter-induced emphysema by switching on mitochondrial NADH dehydrogenase genes.Proc Natl Acad Sci U S A. 2017 Nov 7;114(45):E9655-E9664. doi: 10.1073/pnas.1712465114. Epub 2017 Oct 25.
|
93 |
Adipokine adipsin is associated with the degree of lung fibrosis in asbestos-exposed workers.Respir Med. 2012 Oct;106(10):1435-40. doi: 10.1016/j.rmed.2012.07.003. Epub 2012 Jul 24.
|
94 |
Deficiency of 7 nicotinic acetylcholine receptor attenuates bleomycin-induced lung fibrosis in mice.Mol Med. 2017 Apr;23:34-39. doi: 10.2119/molmed.2016.00083. Epub 2017 Mar 6.
|
95 |
Prognostic Biomarkers of Sarcoidosis: A Comparative Study of Serum Chitotriosidase, ACE, Lysozyme, and KL-6.Dis Markers. 2019 Mar 3;2019:8565423. doi: 10.1155/2019/8565423. eCollection 2019.
|
96 |
Silencing of Carbohydrate Sulfotransferase 15 Hinders Murine Pulmonary Fibrosis Development.Mol Ther Nucleic Acids. 2017 Mar 17;6:163-172. doi: 10.1016/j.omtn.2016.12.008. Epub 2016 Dec 31.
|
97 |
Chymase is activated in the pulmonary inflammation and fibrosis induced by paraquat in hamsters.Tohoku J Exp Med. 2004 Aug;203(4):287-94. doi: 10.1620/tjem.203.287.
|
98 |
Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen.Arthritis Rheum. 2009 Jul;60(7):2142-55. doi: 10.1002/art.24620.
|
99 |
Cytokine-like factor 1 gene expression is enriched in idiopathic pulmonary fibrosis and drives the accumulation of CD4+ T cells in murine lungs: evidence for an antifibrotic role in bleomycin injury.Am J Pathol. 2012 May;180(5):1963-78. doi: 10.1016/j.ajpath.2012.01.010. Epub 2012 Mar 16.
|
100 |
Increased granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) levels in BAL fluid from patients with sulfur mustard gas-induced pulmonary fibrosis.J Aerosol Med. 2007 Fall;20(3):352-60. doi: 10.1089/jam.2007.0590.
|
101 |
Casein Kinase 1/ Inhibitor, PF670462 Attenuates the Fibrogenic Effects of Transforming Growth Factor- in Pulmonary Fibrosis.Front Pharmacol. 2018 Jul 10;9:738. doi: 10.3389/fphar.2018.00738. eCollection 2018.
|
102 |
Gene expression of cytokines and growth factors in the lungs after paraquat administration in mice.Leg Med (Tokyo). 2006 Mar;8(2):102-9. doi: 10.1016/j.legalmed.2005.08.010. Epub 2005 Dec 1.
|
103 |
Megakaryocytes participate in the occurrence of bleomycin-induced pulmonary fibrosis.Cell Death Dis. 2019 Sep 9;10(9):648. doi: 10.1038/s41419-019-1903-8.
|
104 |
[Lung fibrosis induced by mechanical ventilation with different tidal volume in neonatal rats].Zhongguo Dang Dai Er Ke Za Zhi. 2010 Oct;12(10):799-803.
|
105 |
Targeted gene disruption reveals the role of the cysteinyl leukotriene 2 receptor in increased vascular permeability and in bleomycin-induced pulmonary fibrosis in mice.J Biol Chem. 2004 Oct 29;279(44):46129-34. doi: 10.1074/jbc.M407057200. Epub 2004 Aug 24.
|
106 |
Role of a novel immune modulating DDR2-expressing population in silica-induced pulmonary fibrosis.PLoS One. 2017 Jul 10;12(7):e0180724. doi: 10.1371/journal.pone.0180724. eCollection 2017.
|
107 |
Genome-Wide Association Study of Susceptibility to Idiopathic Pulmonary Fibrosis.Am J Respir Crit Care Med. 2020 Mar 1;201(5):564-574. doi: 10.1164/rccm.201905-1017OC.
|
108 |
Role of dual-specificity protein phosphatase DUSP10/MKP-5 in pulmonary fibrosis.Am J Physiol Lung Cell Mol Physiol. 2019 Nov 1;317(5):L678-L689. doi: 10.1152/ajplung.00264.2018. Epub 2019 Sep 4.
|
109 |
Endothelin-converting enzyme-1 gene ablation attenuates pulmonary fibrosis via CGRP-cAMP/EPAC1 pathway.Am J Respir Cell Mol Biol. 2013 Apr;48(4):465-76. doi: 10.1165/rcmb.2012-0354OC.
|
110 |
Activation of PERK in ET-1- and thrombin-induced pulmonary fibroblast differentiation: Inhibitory effects of curcumin.J Cell Physiol. 2019 Sep;234(9):15977-15988. doi: 10.1002/jcp.28256. Epub 2019 Mar 1.
|
111 |
Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis.J Leukoc Biol. 2015 Aug;98(2):143-52. doi: 10.1189/jlb.3HI1014-493R. Epub 2015 Mar 5.
|
112 |
Uncoupling of the profibrotic and hemostatic effects of thrombin in lung fibrosis.JCI Insight. 2017 May 4;2(9):e86608. doi: 10.1172/jci.insight.86608. eCollection 2017 May 4.
|
113 |
Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis.J Cell Mol Med. 2015 Jun;19(6):1346-56. doi: 10.1111/jcmm.12520. Epub 2015 Feb 16.
|
114 |
Protease-activated receptors (PAR)-1 and -3 drive epithelial-mesenchymal transition of alveolar epithelial cells - potential role in lung fibrosis.Thromb Haemost. 2013 Aug;110(2):295-307. doi: 10.1160/TH12-11-0854. Epub 2013 Jun 6.
|
115 |
Adenovirus vector expressing keratinocyte growth factor using CAG promoter impairs pulmonary function of mice with elastase-induced emphysema.Microbiol Immunol. 2017 Jul;61(7):264-271. doi: 10.1111/1348-0421.12492.
|
116 |
Developmental regulation and coordinate reexpression of FKBP65 with extracellular matrix proteins after lung injury suggest a specialized function for this endoplasmic reticulum immunophilin.Cell Stress Chaperones. 2005 Winter;10(4):285-95. doi: 10.1379/csc-118r.1.
|
117 |
Transcription factor Fra-2 and its emerging role in matrix deposition, proliferation and inflammation in chronic lung diseases.Cell Signal. 2019 Dec;64:109408. doi: 10.1016/j.cellsig.2019.109408. Epub 2019 Aug 29.
|
118 |
PACE: A Probabilistic Atlas for Normal Tissue Complication Estimation in Radiation Oncology.Front Oncol. 2019 Mar 13;9:130. doi: 10.3389/fonc.2019.00130. eCollection 2019.
|
119 |
Aberrant expression of miR-125a-3p promotes fibroblast activation via Fyn/STAT3 pathway during silica-induced pulmonary fibrosis.Toxicology. 2019 Feb 15;414:57-67. doi: 10.1016/j.tox.2019.01.007. Epub 2019 Jan 15.
|
120 |
Frizzled-7 mediates TGF--induced pulmonary fibrosis by transmitting non-canonical Wnt signaling.Exp Cell Res. 2017 Oct 1;359(1):226-234. doi: 10.1016/j.yexcr.2017.07.025. Epub 2017 Jul 20.
|
121 |
Genetic loss of Gas6/Mer pathway attenuates silica-induced lung inflammation and fibrosis in mice.Toxicol Lett. 2019 Oct 1;313:178-187. doi: 10.1016/j.toxlet.2019.07.008. Epub 2019 Jul 5.
|
122 |
The Hedgehog target Gli1 is not required for bleomycin-induced lung fibrosis.Exp Lung Res. 2019 Feb-Mar;45(1-2):22-29. doi: 10.1080/01902148.2019.1601795. Epub 2019 Apr 13.
|
123 |
Genetic variation in GREM1 is a risk factor for fibrosis in pulmonary sarcoidosis.Tissue Antigens. 2011 Feb;77(2):112-7. doi: 10.1111/j.1399-0039.2010.01590.x.
|
124 |
Grainyhead-like 2 (GRHL2) distribution reveals novel pathophysiological differences between human idiopathic pulmonary fibrosis and mouse models of pulmonary fibrosis.Am J Physiol Lung Cell Mol Physiol. 2014 Mar 1;306(5):L405-19. doi: 10.1152/ajplung.00143.2013. Epub 2013 Dec 27.
|
125 |
Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR- and subsequent expression of HGF in colons. Toxicol Appl Pharmacol. 2018 Mar 15;343:1-15. doi: 10.1016/j.taap.2018.02.001. Epub 2018 Feb 3.
|
126 |
Synergistic role of HSP90 and HSP90 to promote myofibroblast persistence in lung fibrosis.Eur Respir J. 2018 Jan 31;51(2):1700386. doi: 10.1183/13993003.00386-2017. Print 2018 Feb.
|
127 |
The Hsp27-Mediated IkB-NFB Signaling Axis Promotes Radiation-Induced Lung Fibrosis.Clin Cancer Res. 2019 Sep 1;25(17):5364-5375. doi: 10.1158/1078-0432.CCR-18-3900. Epub 2019 May 24.
|
128 |
Role of heat shock protein 60 (HSP60) on paraquat intoxication.J Appl Toxicol. 2001 Sep-Oct;21(5):425-30. doi: 10.1002/jat.774.
|
129 |
The effects of aerosolized STAT1 antisense oligodeoxynucleotides on rat pulmonary fibrosis.Cell Mol Immunol. 2009 Feb;6(1):51-9. doi: 10.1038/cmi.2009.7.
|
130 |
MicroRNA let-7 Downregulates Ligand-Independent Estrogen Receptor-mediated Male-Predominant Pulmonary Fibrosis.Am J Respir Crit Care Med. 2019 Nov 15;200(10):1246-1257. doi: 10.1164/rccm.201903-0508OC.
|
131 |
Interleukin-11 is a therapeutic target in idiopathic pulmonary fibrosis.Sci Transl Med. 2019 Sep 25;11(511):eaaw1237. doi: 10.1126/scitranslmed.aaw1237.
|
132 |
A profibrotic function of IL-12p40 in experimental pulmonary fibrosis.J Immunol. 2002 Sep 1;169(5):2653-61. doi: 10.4049/jimmunol.169.5.2653.
|
133 |
Role of B7H3/IL-33 Signaling in Pulmonary Fibrosis-induced Profibrogenic Alterations in Bone Marrow.Am J Respir Crit Care Med. 2019 Oct 15;200(8):1032-1044. doi: 10.1164/rccm.201808-1560OC.
|
134 |
IL-1-IL-17 Signaling Axis Contributes to Fibrosis and Inflammation in Two Different Murine Models of Systemic Sclerosis.Front Immunol. 2018 Jul 10;9:1611. doi: 10.3389/fimmu.2018.01611. eCollection 2018.
|
135 |
An ST2-dependent role of bone marrow-derived group 2 innate lymphoid cells in pulmonary fibrosis.J Pathol. 2018 Aug;245(4):399-409. doi: 10.1002/path.5092. Epub 2018 Jun 5.
|
136 |
Elevation of IL-6 and IL-33 Levels in Serum Associated with Lung Fibrosis and Skeletal Muscle Wasting in a Bleomycin-Induced Lung Injury Mouse Model.Mediators Inflamm. 2019 Mar 27;2019:7947596. doi: 10.1155/2019/7947596. eCollection 2019.
|
137 |
Valsartan attenuates bleomycin-induced pulmonary fibrosis by inhibition of NF-B expression and regulation of Th1/Th2 cytokines.Immunopharmacol Immunotoxicol. 2018 Jun;40(3):225-231. doi: 10.1080/08923973.2018.1431924. Epub 2018 Feb 15.
|
138 |
AQX-1125, small molecule SHIP1 activator inhibits bleomycin-induced pulmonary fibrosis.Br J Pharmacol. 2017 Sep;174(18):3045-3057. doi: 10.1111/bph.13934. Epub 2017 Aug 11.
|
139 |
miR-542-5p Attenuates Fibroblast Activation by Targeting Integrin 6 in Silica-Induced Pulmonary Fibrosis.Int J Mol Sci. 2018 Nov 22;19(12):3717. doi: 10.3390/ijms19123717.
|
140 |
Modulation of CD11c+ lung dendritic cells in respect to TGF- in experimental pulmonary fibrosis.Cell Biol Int. 2017 Sep;41(9):991-1000. doi: 10.1002/cbin.10800. Epub 2017 Jul 16.
|
141 |
Expression analysis of microRNAs and mRNAs in myofibroblast differentiation of lung resident mesenchymal stem cells.Differentiation. 2020 Mar-Apr;112:10-16. doi: 10.1016/j.diff.2019.11.002. Epub 2019 Dec 10.
|
142 |
Neutrophil extracellular traps activate lung fibroblast to induce polymyositis-related interstitial lung diseases via TLR9-miR-7-Smad2 pathway.J Cell Mol Med. 2020 Jan;24(2):1658-1669. doi: 10.1111/jcmm.14858. Epub 2019 Dec 10.
|
143 |
LOX/LOXL in pulmonary fibrosis: potential therapeutic targets.J Drug Target. 2019 Aug;27(7):790-796. doi: 10.1080/1061186X.2018.1550649. Epub 2018 Nov 29.
|
144 |
The serum level and significance of lysyl oxidase-like 2 in patients with rheumatoid arthritis-associated interstitial lung disease.Clin Rheumatol. 2018 Jan;37(1):193-198. doi: 10.1007/s10067-017-3878-0. Epub 2017 Oct 19.
|
145 |
The tumor necrosis factor family member LIGHT is a target for asthmatic airway remodeling.Nat Med. 2011 May;17(5):596-603. doi: 10.1038/nm.2356. Epub 2011 Apr 17.
|
146 |
A novel lnc-PCF promotes the proliferation of TGF-1-activated epithelial cells by targeting miR-344a-5p to regulate map3k11 in pulmonary fibrosis.Cell Death Dis. 2017 Oct 26;8(10):e3137. doi: 10.1038/cddis.2017.500.
|
147 |
Tackling MARCKS-PIP3 circuit attenuates fibroblast activation and fibrosis progression.FASEB J. 2019 Dec;33(12):14354-14369. doi: 10.1096/fj.201901705R. Epub 2019 Oct 26.
|
148 |
Early treatment with fumagillin, an inhibitor of methionine aminopeptidase-2, prevents Pulmonary Hypertension in monocrotaline-injured rats.PLoS One. 2012;7(4):e35388. doi: 10.1371/journal.pone.0035388. Epub 2012 Apr 11.
|
149 |
Matrix metalloproteinase-1 polymorphism (-1607G) and disease severity in non-cystic fibrosis bronchiectasis in Taiwan.PLoS One. 2013 Jun 11;8(6):e66265. doi: 10.1371/journal.pone.0066265. Print 2013.
|
150 |
Fructose-1,6-bisphosphate prevents pulmonary fibrosis by regulating extracellular matrix deposition and inducing phenotype reversal of lung myofibroblasts.PLoS One. 2019 Sep 11;14(9):e0222202. doi: 10.1371/journal.pone.0222202. eCollection 2019.
|
151 |
Lung collagens perpetuate pulmonary fibrosis via CD204 and M2 macrophage activation.PLoS One. 2013 Nov 20;8(11):e81382. doi: 10.1371/journal.pone.0081382. eCollection 2013.
|
152 |
Oral N-acetylcysteine reduces bleomycin-induced lung damage and mucin Muc5ac expression in rats.Eur Respir J. 2003 Dec;22(6):900-5. doi: 10.1183/09031936.03.00018003.
|
153 |
MLN4924 protects against bleomycin-induced pulmonary fibrosis by inhibiting the early inflammatory process.Am J Transl Res. 2017 Apr 15;9(4):1810-1821. eCollection 2017.
|
154 |
Rapamycin attenuates the paraquat-induced pulmonary fibrosis through activating Nrf2 pathway.J Cell Physiol. 2020 Feb;235(2):1759-1768. doi: 10.1002/jcp.29094. Epub 2019 Jul 12.
|
155 |
Carbon black nanoparticles induce pulmonary fibrosis through NLRP3 inflammasome pathway modulated by miR-96 targeted FOXO3a.Chemosphere. 2020 Feb;241:125075. doi: 10.1016/j.chemosphere.2019.125075. Epub 2019 Oct 11.
|
156 |
Cell type- and tissue-specific functions of ecto-5'-nucleotidase (CD73).Am J Physiol Cell Physiol. 2019 Dec 1;317(6):C1079-C1092. doi: 10.1152/ajpcell.00285.2019. Epub 2019 Aug 28.
|
157 |
The purinergic receptor subtype P2Y2 mediates chemotaxis of neutrophils and fibroblasts in fibrotic lung disease.Oncotarget. 2017 May 30;8(22):35962-35972. doi: 10.18632/oncotarget.16414.
|
158 |
MiR-541-5p regulates lung fibrosis by targeting cyclic nucleotide phosphodiesterase 1A.Exp Lung Res. 2017 Aug-Sep;43(6-7):249-258. doi: 10.1080/01902148.2017.1349210. Epub 2017 Aug 17.
|
159 |
Fatal pulmonary fibrosis associated with BCNU: the relative role of platelet-derived growth factor-B, insulin-like growth factor I, transforming growth factor-beta1 and cyclooxygenase-2. Bone Marrow Transplant. 2004 Oct;34(7):609-14. doi: 10.1038/sj.bmt.1704616.
|
160 |
Blockade of platelet-derived growth factor receptor-, not receptor- ameliorates bleomycin-induced pulmonary fibrosis in mice.PLoS One. 2018 Dec 31;13(12):e0209786. doi: 10.1371/journal.pone.0209786. eCollection 2018.
|
161 |
Inactivation of urokinase-type plasminogen activator receptor (uPAR) gene induces dermal and pulmonary fibrosis and peripheral microvasculopathy in mice: a new model of experimental scleroderma?.Ann Rheum Dis. 2014 Sep;73(9):1700-9. doi: 10.1136/annrheumdis-2013-203706. Epub 2013 Jul 12.
|
162 |
Glycogen Synthase Kinase-3 Inhibition with 9-ING-41 Attenuates the Progression of Pulmonary Fibrosis.Sci Rep. 2019 Dec 12;9(1):18925. doi: 10.1038/s41598-019-55176-w.
|
163 |
Cross-Talk between Transforming Growth Factor- and Periostin Can Be Targeted for Pulmonary Fibrosis.Am J Respir Cell Mol Biol. 2020 Feb;62(2):204-216. doi: 10.1165/rcmb.2019-0245OC.
|
164 |
Protein Tyrosine Phosphatase-N13 Promotes Myofibroblast Resistance to Apoptosis in Idiopathic Pulmonary Fibrosis.Am J Respir Crit Care Med. 2018 Oct 1;198(7):914-927. doi: 10.1164/rccm.201707-1497OC.
|
165 |
Upregulation of RGS2: a new mechanism for pirfenidone amelioration of pulmonary fibrosis.Respir Res. 2016 Aug 22;17(1):103. doi: 10.1186/s12931-016-0418-4.
|
166 |
Effectiveness of pulmonary rehabilitation in patients with interstitial lung disease of different etiology: a multicenter prospective study.BMC Pulm Med. 2017 Oct 10;17(1):130. doi: 10.1186/s12890-017-0476-5.
|
167 |
Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis.Am J Respir Cell Mol Biol. 2007 Sep;37(3):309-21. doi: 10.1165/rcmb.2006-0455OC. Epub 2007 May 11.
|
168 |
Expression of RXFP1 Is Decreased in Idiopathic Pulmonary Fibrosis. Implications for Relaxin-based Therapies.Am J Respir Crit Care Med. 2016 Dec 1;194(11):1392-1402. doi: 10.1164/rccm.201509-1865OC.
|
169 |
S100A4(+) Macrophages Are Necessary for Pulmonary Fibrosis by Activating Lung Fibroblasts.Front Immunol. 2018 Aug 6;9:1776. doi: 10.3389/fimmu.2018.01776. eCollection 2018.
|
170 |
Deficiency of Sphingosine-1-Phosphate Receptor 2 (S1P(2)) Attenuates Bleomycin-Induced Pulmonary Fibrosis.Biomol Ther (Seoul). 2019 May 1;27(3):318-326. doi: 10.4062/biomolther.2018.131.
|
171 |
S1PR3 deficiency alleviates radiation-induced pulmonary fibrosis through the regulation of epithelial-mesenchymal transition by targeting miR-495-3p.J Cell Physiol. 2020 Mar;235(3):2310-2324. doi: 10.1002/jcp.29138. Epub 2019 Sep 5.
|
172 |
Deficiency of Psgl-1 accelerates bleomycin (BLM)-induced lung fibrosis and inflammation in mice through activating PI3K/AKT.Biochem Biophys Res Commun. 2017 Sep 16;491(2):558-565. doi: 10.1016/j.bbrc.2017.03.003. Epub 2017 Mar 3.
|
173 |
Treatment of pulmonary fibrosis with siRNA against a collagen-specific chaperone HSP47 in vitamin A-coupled liposomes.Exp Lung Res. 2017 Aug-Sep;43(6-7):271-282. doi: 10.1080/01902148.2017.1354946. Epub 2017 Oct 16.
|
174 |
Identification and Characterizations of Novel, Selective Histone Methyltransferase SET7 Inhibitors by Scaffold Hopping- and 2D-Molecular Fingerprint-Based Similarity Search.Molecules. 2018 Mar 2;23(3):567. doi: 10.3390/molecules23030567.
|
175 |
Naftopidil reduced the proliferation of lung fibroblasts and bleomycin-induced lung fibrosis in mice.J Cell Mol Med. 2019 May;23(5):3563-3571. doi: 10.1111/jcmm.14255. Epub 2019 Mar 15.
|
176 |
Quercetin ameliorates pulmonary fibrosis by inhibiting SphK1/S1P signaling.Biochem Cell Biol. 2018 Dec;96(6):742-751. doi: 10.1139/bcb-2017-0302. Epub 2018 Jun 25.
|
177 |
Novel Insights on Systemic and Brain Aging, Stroke, Amyotrophic Lateral Sclerosis, and Alzheimer's Disease.Aging Dis. 2019 Apr 1;10(2):470-482. doi: 10.14336/AD.2019.0330. eCollection 2019 Apr.
|
178 |
Costunolide inhibits pulmonary fibrosis via regulating NF-kB and TGF-(1)/Smad(2)/Nrf(2)-NOX(4) signaling pathways.Biochem Biophys Res Commun. 2019 Mar 5;510(2):329-333. doi: 10.1016/j.bbrc.2019.01.104. Epub 2019 Jan 29.
|
179 |
Osteopontin lung gene expression is a marker of disease severity in pulmonary arterial hypertension.Respirology. 2019 Nov;24(11):1104-1110. doi: 10.1111/resp.13557. Epub 2019 Apr 8.
|
180 |
STAT1-dependent and -independent pulmonary allergic and fibrogenic responses in mice after exposure to tangled versus rod-like multi-walled carbon nanotubes.Part Fibre Toxicol. 2017 Jul 17;14(1):26. doi: 10.1186/s12989-017-0207-3.
|
181 |
Overexpression of Sulf2 in idiopathic pulmonary fibrosis.Glycobiology. 2013 Jun;23(6):709-19. doi: 10.1093/glycob/cwt010. Epub 2013 Feb 14.
|
182 |
Lung Transplant Outcomes in Patients With Pulmonary Fibrosis With Telomere-Related Gene Variants.Chest. 2019 Sep;156(3):477-485. doi: 10.1016/j.chest.2019.03.030. Epub 2019 Apr 9.
|
183 |
Longitudinal free-breathing MRI measurement of murine lung physiology in a progressive model of lung fibrosis.J Appl Physiol (1985). 2019 Apr 1;126(4):1138-1149. doi: 10.1152/japplphysiol.00993.2018. Epub 2019 Feb 7.
|
184 |
The CDR1as/miR-7/TGFBR2 Axis Modulates EMT in Silica-Induced Pulmonary Fibrosis.Toxicol Sci. 2018 Dec 1;166(2):465-478. doi: 10.1093/toxsci/kfy221.
|
185 |
TIAM1 inhibits lung fibroblast differentiation in pulmonary fibrosis.Exp Ther Med. 2017 Nov;14(5):4254-4262. doi: 10.3892/etm.2017.5024. Epub 2017 Aug 24.
|
186 |
BAX inhibitor-1-associated V-ATPase glycosylation enhances collagen degradation in pulmonary fibrosis.Cell Death Dis. 2014 Mar 13;5(3):e1113. doi: 10.1038/cddis.2014.86.
|
187 |
Human airway trypsin-like protease exerts potent, antifibrotic action in pulmonary fibrosis.FASEB J. 2018 Mar;32(3):1250-1264. doi: 10.1096/fj.201700583R. Epub 2018 Jan 3.
|
188 |
Anti-fibrotic effects of pirfenidone and rapamycin in primary IPF fibroblasts and human alveolar epithelial cells.BMC Pulm Med. 2018 Apr 27;18(1):63. doi: 10.1186/s12890-018-0626-4.
|
189 |
Localized expression of tenascin in systemic sclerosis-associated pulmonary fibrosis and its regulation by insulin-like growth factor binding protein 3.Arthritis Rheum. 2012 Jan;64(1):272-80. doi: 10.1002/art.30647.
|
190 |
Pathogenic roles of B lymphocytes in systemic sclerosis.Immunol Lett. 2018 Mar;195:76-82. doi: 10.1016/j.imlet.2018.01.002. Epub 2018 Jan 5.
|
191 |
Serotonin Exhibits Accelerated Bleomycin-Induced Pulmonary Fibrosis through TPH1 Knockout Mouse Experiments.Mediators Inflamm. 2018 Apr 16;2018:7967868. doi: 10.1155/2018/7967868. eCollection 2018.
|
192 |
Cdc42-interacting protein 4 silencing relieves pulmonary fibrosis in STZ-induced diabetic mice via the Wnt/GSK-3/-catenin pathway.Exp Cell Res. 2017 Oct 1;359(1):284-290. doi: 10.1016/j.yexcr.2017.07.018. Epub 2017 Jul 16.
|
193 |
Increased expression of lung TRPV1/TRPA1 in a cough model of bleomycin-induced pulmonary fibrosis in Guinea pigs.BMC Pulm Med. 2019 Feb 4;19(1):27. doi: 10.1186/s12890-019-0792-z.
|
194 |
Transient receptor potential (TRP) channels as molecular targets in lung toxicology and associated diseases.Cell Calcium. 2017 Nov;67:123-137. doi: 10.1016/j.ceca.2017.04.005. Epub 2017 Apr 26.
|
195 |
Macrophage-secreted TSLP and MMP9 promote bleomycin-induced pulmonary fibrosis.Toxicol Appl Pharmacol. 2019 Mar 1;366:10-16. doi: 10.1016/j.taap.2019.01.011. Epub 2019 Jan 14.
|
196 |
Pregnancy exposure to carbon black nanoparticles exacerbates bleomycin-induced lung fibrosis in offspring via disrupting LKB1-AMPK-ULK1 axis-mediated autophagy.Toxicology. 2019 Sep 1;425:152244. doi: 10.1016/j.tox.2019.152244. Epub 2019 Jul 11.
|
197 |
Distribution of von Willebrand factor in capillary endothelial cells of rat lungs with pulmonary fibrosis.Exp Toxicol Pathol. 1996 Jun;48(4):283-8. doi: 10.1016/S0940-2993(96)80020-0.
|
198 |
IL-37 Attenuates Lung Fibrosis by Inducing Autophagy and Regulating TGF-1 Production in Mice.J Immunol. 2019 Oct 15;203(8):2265-2275. doi: 10.4049/jimmunol.1801515. Epub 2019 Sep 13.
|
199 |
ABCA3 mutations led to pulmonary fibrosis and emphysema with pulmonary hypertension in an 8-year-old girl.Pediatr Pulmonol. 2016 Jun;51(6):E21-3. doi: 10.1002/ppul.23379. Epub 2016 Jan 18.
|
200 |
Annexin A11 is associated with pulmonary fibrosis in African American patients with sarcoidosis.Sarcoidosis Vasc Diffuse Lung Dis. 2016 Dec 23;33(4):418-422.
|
201 |
Bleomycin hydrolase and a genetic locus within the MHC affect risk for pulmonary fibrosis in mice.Hum Mol Genet. 2002 Aug 1;11(16):1855-63. doi: 10.1093/hmg/11.16.1855.
|
202 |
Dimethylarginine dimethylaminohydrolase 1 deficiency aggravates monocrotaline-induced pulmonary oxidative stress, pulmonary arterial hypertension and right heart failure in rats.Int J Cardiol. 2019 Nov 15;295:14-20. doi: 10.1016/j.ijcard.2019.07.078. Epub 2019 Jul 27.
|
203 |
Reduced expression of BMP3 contributes to the development of pulmonary fibrosis and predicts the unfavorable prognosis in IIP patients.Oncotarget. 2017 Aug 9;8(46):80531-80544. doi: 10.18632/oncotarget.20083. eCollection 2017 Oct 6.
|
204 |
In Situ Imaging of Tissue Remodeling with Collagen Hybridizing Peptides.ACS Nano. 2017 Oct 24;11(10):9825-9835. doi: 10.1021/acsnano.7b03150. Epub 2017 Sep 18.
|
205 |
Beclin 1, LC3, and p62 expression in paraquat-induced pulmonary fibrosis.Hum Exp Toxicol. 2019 Jul;38(7):794-802. doi: 10.1177/0960327119842633. Epub 2019 Apr 12.
|
206 |
A case report of heterozygous TINF2 gene mutation associated with pulmonary fibrosis in a patient with dyskeratosis congenita.Medicine (Baltimore). 2018 May;97(19):e0724. doi: 10.1097/MD.0000000000010724.
|
207 |
Increased circulating desmosine and age-dependent elastinolysis in idiopathic pulmonary fibrosis.Respir Res. 2018 Mar 20;19(1):45. doi: 10.1186/s12931-018-0747-6.
|
208 |
High expression of FAM13A was associated with increasing the liver cirrhosis risk.Mol Genet Genomic Med. 2019 Mar;7(3):e543. doi: 10.1002/mgg3.543. Epub 2019 Jan 2.
|
209 |
Association of HLA-DPB1 with scleroderma and its clinical features in Chinese population.PLoS One. 2014 Jan 31;9(1):e87363. doi: 10.1371/journal.pone.0087363. eCollection 2014.
|
210 |
Increased expression of latent TGF--binding protein 4 affects the fibrotic process in scleroderma by TGF-/SMAD signaling.Lab Invest. 2017 May;97(5):591-601. doi: 10.1038/labinvest.2017.20. Epub 2017 Mar 6.
|
211 |
Identification of periplakin as a major regulator of lung injury and repair in mice.JCI Insight. 2018 Mar 8;3(5):e90163. doi: 10.1172/jci.insight.90163.
|
212 |
Role of SOD3 in silica-related lung fibrosis and pulmonary vascular remodeling.Respir Res. 2018 Nov 20;19(1):221. doi: 10.1186/s12931-018-0933-6.
|
213 |
TMEM100 mediates inflammatory cytokines secretion in hepatic stellate cells and its mechanism research.Toxicol Lett. 2019 Dec 15;317:82-91. doi: 10.1016/j.toxlet.2018.12.010. Epub 2019 Jan 11.
|
214 |
miR-142-5p and miR-130a-3p are regulated by IL-4 and IL-13 and control profibrogenic macrophage program.Nat Commun. 2015 Oct 5;6:8523. doi: 10.1038/ncomms9523.
|
215 |
Cleavage factor 25 deregulation contributes to pulmonary fibrosis through alternative polyadenylation.J Clin Invest. 2019 Feb 28;129(5):1984-1999. doi: 10.1172/JCI122106. Print 2019 May 1.
|
216 |
Pirfenidone attenuates lung fibrotic fibroblast responses to transforming growth factor-1.Respir Res. 2019 Jun 11;20(1):119. doi: 10.1186/s12931-019-1093-z.
|
217 |
CXCL16/CXCR6 axis promotes bleomycin-induced fibrotic process in MRC-5 cells via the PI3K/AKT/FOXO3a pathway.Int Immunopharmacol. 2020 Apr;81:106035. doi: 10.1016/j.intimp.2019.106035. Epub 2019 Nov 19.
|
218 |
A Novel Variant of Desmoplakin Is Potentially Associated with Silicosis Risk.DNA Cell Biol. 2018 Nov;37(11):925-931. doi: 10.1089/dna.2018.4370. Epub 2018 Sep 12.
|
219 |
The effects of atorvastatin on the kidney injury in mice with pulmonary fibrosis.J Pharm Pharmacol. 2019 Aug;71(8):1301-1310. doi: 10.1111/jphp.13128. Epub 2019 Jun 18.
|
220 |
Involvement of GPx4-Regulated Lipid Peroxidation in Idiopathic Pulmonary Fibrosis Pathogenesis.J Immunol. 2019 Oct 15;203(8):2076-2087. doi: 10.4049/jimmunol.1801232. Epub 2019 Sep 18.
|
221 |
A novel mutation causes Hermansky-Pudlak syndrome type 4 with pulmonary fibrosis in 2 siblings from China.Medicine (Baltimore). 2019 Aug;98(33):e16899. doi: 10.1097/MD.0000000000016899.
|
222 |
Interleukin-18 promotes fibroblast senescence in pulmonary fibrosis through down-regulating Klotho expression.Biomed Pharmacother. 2019 May;113:108756. doi: 10.1016/j.biopha.2019.108756. Epub 2019 Mar 11.
|
223 |
The association of LAMB1 polymorphism and expression changes with the risk of coal workers' pneumoconiosis.Environ Toxicol. 2017 Sep;32(9):2182-2190. doi: 10.1002/tox.22431. Epub 2017 Apr 26.
|
224 |
Lysocardiolipin acyltransferase regulates TGF- mediated lung fibroblast differentiation.Free Radic Biol Med. 2017 Nov;112:162-173. doi: 10.1016/j.freeradbiomed.2017.07.023. Epub 2017 Jul 24.
|
225 |
Lysyl Oxidase-Like 1 Protein Deficiency Protects Mice from Adenoviral Transforming Growth Factor-1-induced Pulmonary Fibrosis.Am J Respir Cell Mol Biol. 2018 Apr;58(4):461-470. doi: 10.1165/rcmb.2017-0252OC.
|
226 |
Susceptibility of microtubule-associated protein 1 light chain 3 (MAP1LC3B/LC3B) knockout mice to lung injury and fibrosis.FASEB J. 2019 Nov;33(11):12392-12408. doi: 10.1096/fj.201900854R. Epub 2019 Aug 20.
|
227 |
Therapeutic effects of scavenger receptor MARCO ligand on silica-induced pulmonary fibrosis in rats.Toxicol Lett. 2019 Sep 1;311:1-10. doi: 10.1016/j.toxlet.2019.04.026. Epub 2019 Apr 24.
|
228 |
Mitochondrial calcium uniporter regulates PGC-1 expression to mediate metabolic reprogramming in pulmonary fibrosis.Redox Biol. 2019 Sep;26:101307. doi: 10.1016/j.redox.2019.101307. Epub 2019 Aug 25.
|
229 |
Augmented production of chemokines (monocyte chemotactic protein-1 (MCP-1), macrophage inflammatory protein-1alpha (MIP-1alpha) and MIP-1beta) in patients with systemic sclerosis: MCP-1 and MIP-1alpha may be involved in the development of pulmonary fibrosis.Clin Exp Immunol. 1999 Jul;117(1):159-65. doi: 10.1046/j.1365-2249.1999.00929.x.
|
230 |
P311 Promotes Lung Fibrosis via Stimulation of Transforming Growth Factor-1, -2, and -3 Translation.Am J Respir Cell Mol Biol. 2019 Feb;60(2):221-231. doi: 10.1165/rcmb.2018-0028OC.
|
231 |
A homozygous SFTPA1 mutation drives necroptosis of type II alveolar epithelial cells in patients with idiopathic pulmonary fibrosis.J Exp Med. 2019 Dec 2;216(12):2724-2735. doi: 10.1084/jem.20182351. Epub 2019 Oct 10.
|
232 |
A Human Gain-of-Function STING Mutation Causes Immunodeficiency and Gammaherpesvirus-Induced Pulmonary Fibrosis in Mice.J Virol. 2019 Feb 5;93(4):e01806-18. doi: 10.1128/JVI.01806-18. Print 2019 Feb 15.
|
233 |
Cell-surface translocation of annexin A2 contributes to bleomycin-induced pulmonary fibrosis by mediating inflammatory response in mice.Clin Sci (Lond). 2019 Apr 15;133(7):789-804. doi: 10.1042/CS20180687.
|
234 |
Classification of Genes: Standardized Clinical Validity Assessment of Gene-Disease Associations Aids Diagnostic Exome Analysis and Reclassifications. Hum Mutat. 2017 May;38(5):600-608. doi: 10.1002/humu.23183. Epub 2017 Feb 13.
|
235 |
Tetraspanin 1 as a mediator of fibrosis inhibits EMT process and Smad2/3 and beta-catenin pathway in human pulmonary fibrosis.J Cell Mol Med. 2019 May;23(5):3583-3596. doi: 10.1111/jcmm.14258. Epub 2019 Mar 14.
|
236 |
Angiotensin-converting enzyme defines matrikine-regulated inflammation and fibrosis.JCI Insight. 2017 Nov 16;2(22):e91923. doi: 10.1172/jci.insight.91923. eCollection 2017 Nov 16.
|
237 |
The atypical chemokine receptor ACKR2 drives pulmonary fibrosis by tuning influx of CCR2(+) and CCR5(+) IFN-producing T cells in mice.Am J Physiol Lung Cell Mol Physiol. 2018 Jun 1;314(6):L1010-L1025. doi: 10.1152/ajplung.00233.2017. Epub 2018 Feb 22.
|
238 |
Cell-surface phenotyping identifies CD36 and CD97 as novel markers of fibroblast quiescence in lung fibrosis.Am J Physiol Lung Cell Mol Physiol. 2018 Nov 1;315(5):L682-L696. doi: 10.1152/ajplung.00439.2017. Epub 2018 Jun 28.
|
239 |
Aortic carboxypeptidase-like protein is expressed in fibrotic human lung and its absence protects against bleomycin-induced lung fibrosis.Am J Pathol. 2009 Mar;174(3):818-28. doi: 10.2353/ajpath.2009.080856. Epub 2009 Jan 29.
|
240 |
Cross talk between Id1 and its interactive protein Dril1 mediate fibroblast responses to transforming growth factor-beta in pulmonary fibrosis.Am J Pathol. 2008 Aug;173(2):337-46. doi: 10.2353/ajpath.2008.070915. Epub 2008 Jun 26.
|
241 |
Senolytic drugs targetalveolar epithelial cell function and attenuate experimental lung fibrosis ex vivo.Eur Respir J. 2017 Aug 3;50(2):1602367. doi: 10.1183/13993003.02367-2016. Print 2017 Aug.
|
242 |
Autophagy induction by celastrol augments protection against bleomycin-induced experimental pulmonary fibrosis in rats: Role of adaptor protein p62/ SQSTM1.Pulm Pharmacol Ther. 2017 Aug;45:47-61. doi: 10.1016/j.pupt.2017.04.003. Epub 2017 Apr 4.
|
243 |
Impaired autophagic activity and ATG4B deficiency are associated with increased endoplasmic reticulum stress-induced lung injury.Aging (Albany NY). 2018 Aug 27;10(8):2098-2112. doi: 10.18632/aging.101532.
|
244 |
Evaluation of Renin and Soluble (Pro)renin Receptor in Patients with IPF. A Comparison with Hypersensitivity Pneumonitis.Lung. 2019 Dec;197(6):715-720. doi: 10.1007/s00408-019-00278-5. Epub 2019 Oct 15.
|
245 |
Oxidative stress induces club cell proliferation and pulmonary fibrosis in Atp8b1 mutant mice.Aging (Albany NY). 2019 Jan 13;11(1):209-229. doi: 10.18632/aging.101742.
|
246 |
Glycosyltransferases and glycosaminoglycans in bleomycin and transforming growth factor-1-induced pulmonary fibrosis.Am J Respir Cell Mol Biol. 2014 Mar;50(3):583-94. doi: 10.1165/rcmb.2012-0226OC.
|
247 |
Increased deposition of chondroitin/dermatan sulfate glycosaminoglycan and upregulation of 1,3-glucuronosyltransferase I in pulmonary fibrosis.Am J Physiol Lung Cell Mol Physiol. 2011 Feb;300(2):L191-203. doi: 10.1152/ajplung.00214.2010. Epub 2010 Nov 5.
|
248 |
Novel and extensive aspects of paraquat-induced pulmonary fibrogenesis: comparative and time-course microarray analyses in fibrogenic and non-fibrogenic rats.J Toxicol Sci. 2007 Dec;32(5):529-53. doi: 10.2131/jts.32.529.
|
249 |
BARD1 mediates TGF- signaling in pulmonary fibrosis.Respir Res. 2015 Sep 29;16:118. doi: 10.1186/s12931-015-0278-3.
|
250 |
Antifibrotic action of Yifei Sanjie formula enhanced autophagy via PI3K-AKT-mTOR signaling pathway in mouse model of pulmonary fibrosis.Biomed Pharmacother. 2019 Oct;118:109293. doi: 10.1016/j.biopha.2019.109293. Epub 2019 Aug 8.
|
251 |
Calpain 9 as a therapeutic target in TGF-induced mesenchymal transition and fibrosis.Sci Transl Med. 2019 Jul 17;11(501):eaau2814. doi: 10.1126/scitranslmed.aau2814.
|
252 |
The calpain inhibitor calpeptin prevents bleomycin-induced pulmonary fibrosis in mice.Clin Exp Immunol. 2010 Dec;162(3):560-7. doi: 10.1111/j.1365-2249.2010.04257.x. Epub 2010 Sep 15.
|
253 |
CBX5/G9a/H3K9me-mediated gene repression is essential to fibroblast activation during lung fibrosis.JCI Insight. 2019 May 16;5(12):e127111. doi: 10.1172/jci.insight.127111.
|
254 |
Performance of Candidate Serum Biomarkers for Systemic Sclerosis-Associated Interstitial Lung Disease.Arthritis Rheumatol. 2019 Jun;71(6):972-982. doi: 10.1002/art.40815. Epub 2019 Apr 26.
|
255 |
Blockade of CCL24 with a monoclonal antibody ameliorates experimental dermal and pulmonary fibrosis.Ann Rheum Dis. 2019 Sep;78(9):1260-1268. doi: 10.1136/annrheumdis-2019-215119. Epub 2019 May 25.
|
256 |
WISP1 mediates IL-6-dependent proliferation in primary human lung fibroblasts.Sci Rep. 2016 Feb 12;6:20547. doi: 10.1038/srep20547.
|
257 |
CCN5 overexpression inhibits profibrotic phenotypes via the PI3K/Akt signaling pathway in lung fibroblasts isolated from patients with idiopathic pulmonary fibrosis and in an in vivo model of lung fibrosis.Int J Mol Med. 2014 Feb;33(2):478-86. doi: 10.3892/ijmm.2013.1565. Epub 2013 Nov 25.
|
258 |
WISP3 prevents fibroblast-myofibroblast transdifferentiation in NRK-49F cells.Biomed Pharmacother. 2018 Mar;99:306-312. doi: 10.1016/j.biopha.2018.01.005.
|
259 |
CCR10+ epithelial cells from idiopathic pulmonary fibrosis lungs drive remodeling.JCI Insight. 2018 Aug 23;3(16):e122211. doi: 10.1172/jci.insight.122211. eCollection 2018 Aug 23.
|
260 |
Tetraspanin CD151 protects against pulmonary fibrosis by maintaining epithelial integrity.Am J Respir Crit Care Med. 2012 Jul 15;186(2):170-80. doi: 10.1164/rccm.201201-0117OC. Epub 2012 May 16.
|
261 |
Cub domain-containing protein 1 negatively regulates TGF- signaling and myofibroblast differentiation.Am J Physiol Lung Cell Mol Physiol. 2018 May 1;314(5):L695-L707. doi: 10.1152/ajplung.00205.2017. Epub 2018 Jan 4.
|
262 |
Triptolide protects against TGF-1-induced pulmonary fibrosis by regulating FAK/calpain signaling.Exp Ther Med. 2019 Dec;18(6):4781-4789. doi: 10.3892/etm.2019.8127. Epub 2019 Oct 25.
|
263 |
Cysteine-rich protein 1 is regulated by transforming growth factor-1 and expressed in lung fibrosis.J Cell Physiol. 2012 Jun;227(6):2605-12. doi: 10.1002/jcp.23000.
|
264 |
Therapeutic effect of ulinastatin on pulmonary fibrosis via downregulation of TGF?, TNF?and NFB.Mol Med Rep. 2018 Jan;17(1):1717-1723. doi: 10.3892/mmr.2017.8056. Epub 2017 Nov 14.
|
265 |
Antifibrotic properties of caveolin-1 scaffolding domain in vitro and in vivo.Am J Physiol Lung Cell Mol Physiol. 2008 May;294(5):L843-61. doi: 10.1152/ajplung.00295.2007. Epub 2008 Jan 18.
|
266 |
Localized hypoxia links ER stress to lung fibrosis through induction of C/EBP homologous protein.JCI Insight. 2018 Aug 23;3(16):e99543. doi: 10.1172/jci.insight.99543. eCollection 2018 Aug 23.
|
267 |
NADPH Oxidases and Aging Models of Lung Fibrosis.Methods Mol Biol. 2019;1982:487-496. doi: 10.1007/978-1-4939-9424-3_29.
|
268 |
Thyroid hormone inhibits lung fibrosis in mice by improving epithelial mitochondrial function.Nat Med. 2018 Jan;24(1):39-49. doi: 10.1038/nm.4447. Epub 2017 Dec 4.
|
269 |
The profibrotic effect of downregulated Na,KATPase 1 subunit in alveolar epithelial cells during lung fibrosis.Int J Mol Med. 2019 Jul;44(1):273-280. doi: 10.3892/ijmm.2019.4201. Epub 2019 May 16.
|
270 |
Pharmacological targeting of BET proteins attenuates radiation-induced lung fibrosis.Sci Rep. 2018 Jan 17;8(1):998. doi: 10.1038/s41598-018-19343-9.
|
271 |
Overexpressing p130/E2F4 in mesenchymal stem cells facilitates the repair of injured alveolar epithelial cells in LPS-induced ARDS mice.Stem Cell Res Ther. 2019 Mar 6;10(1):74. doi: 10.1186/s13287-019-1169-1.
|
272 |
Associations of Pulmonary Fibrosis with Peripheral Blood Th1/Th2 Cell Imbalance and EBF3 Gene Methylation in Uygur Pigeon Breeder's Lung Patients.Cell Physiol Biochem. 2018;47(3):1141-1151. doi: 10.1159/000490208. Epub 2018 Jun 15.
|
273 |
The Oncogene ECT2 Contributes to a Hyperplastic, Proliferative Lung Epithelial Cell Phenotype in Idiopathic Pulmonary Fibrosis.Am J Respir Cell Mol Biol. 2019 Dec;61(6):713-726. doi: 10.1165/rcmb.2019-0047OC.
|
274 |
Inhibitory effect of l-mimosine on bleomycin-induced pulmonary fibrosis in rats: Role of eIF3a and p27.Int Immunopharmacol. 2015 Jul;27(1):53-64. doi: 10.1016/j.intimp.2015.04.048. Epub 2015 May 5.
|
275 |
ELMOD2 is a candidate gene for familial idiopathic pulmonary fibrosis.Am J Hum Genet. 2006 Jul;79(1):149-54. doi: 10.1086/504639. Epub 2006 May 9.
|
276 |
Deranged fatty acid composition causes pulmonary fibrosis in Elovl6-deficient mice.Nat Commun. 2013;4:2563. doi: 10.1038/ncomms3563.
|
277 |
Shared and Tissue-Specific Expression Signatures between Bone Marrow from Primary Myelofibrosis and Essential Thrombocythemia.Exp Hematol. 2019 Nov;79:16-25.e3. doi: 10.1016/j.exphem.2019.10.001. Epub 2019 Nov 1.
|
278 |
Family of hereditary fibrosing poikiloderma with tendon contractures, myopathy and pulmonary fibrosis caused by a novel FAM111B mutation.J Dermatol. 2019 Nov;46(11):1014-1018. doi: 10.1111/1346-8138.15045. Epub 2019 Aug 7.
|
279 |
Therapeutic effect of a peptide inhibitor of TGF- on pulmonary fibrosis.Cytokine. 2011 Mar;53(3):327-33. doi: 10.1016/j.cyto.2010.11.019. Epub 2010 Dec 23.
|
280 |
Ethnicity and race and systemic sclerosis: how it affects susceptibility, severity, antibody genetics, and clinical manifestations.Curr Rheumatol Rep. 2003 Apr;5(2):160-7. doi: 10.1007/s11926-003-0045-1.
|
281 |
Identification of molecular signatures involved in radiation-induced lung fibrosis.J Mol Med (Berl). 2019 Jan;97(1):37-47. doi: 10.1007/s00109-018-1715-9. Epub 2018 Nov 7.
|
282 |
The FMS-like tyrosine kinase-3 ligand/lung dendritic cell axis contributes to regulation of pulmonary fibrosis.Thorax. 2019 Oct;74(10):947-957. doi: 10.1136/thoraxjnl-2018-212603. Epub 2019 May 10.
|
283 |
FOXF1 Inhibits Pulmonary Fibrosis by Preventing CDH2-CDH11 Cadherin Switch in Myofibroblasts.Cell Rep. 2018 Apr 10;23(2):442-458. doi: 10.1016/j.celrep.2018.03.067.
|
284 |
Haplodeletion of Follistatin-Like 1 Attenuates Radiation-Induced Pulmonary Fibrosis in Mice.Int J Radiat Oncol Biol Phys. 2019 Jan 1;103(1):208-216. doi: 10.1016/j.ijrobp.2018.08.035. Epub 2018 Aug 29.
|
285 |
The effect of core fucosylation-mediated regulation of multiple signaling pathways on lung pericyte activation and fibrosis.Int J Biochem Cell Biol. 2019 Dec;117:105639. doi: 10.1016/j.biocel.2019.105639. Epub 2019 Oct 24.
|
286 |
Increased levels of Gab1 and Gab2 adaptor proteins skew interleukin-4 (IL-4) signaling toward M2 macrophage-driven pulmonary fibrosis in mice.J Biol Chem. 2017 Aug 25;292(34):14003-14015. doi: 10.1074/jbc.M117.802066. Epub 2017 Jul 7.
|
287 |
Geranylgeranyl diphosphate synthase deficiency aggravates lung fibrosis in mice by modulating TGF-1/BMP-4 signaling.Biol Chem. 2019 Nov 26;400(12):1617-1627. doi: 10.1515/hsz-2019-0168.
|
288 |
Effects of dynamic changes in histone acetylation and deacetylase activity on pulmonary fibrosis.Int Immunopharmacol. 2017 Nov;52:272-280. doi: 10.1016/j.intimp.2017.09.020. Epub 2017 Sep 27.
|
289 |
Changes in factor VII-activating protease in a bleomycin-induced lung injury rat model and its influence on human pulmonary fibroblasts in vitro.Int J Mol Med. 2010 Oct;26(4):549-55. doi: 10.3892/ijmm_00000498.
|
290 |
Protocatechuic aldehyde ameliorates experimental pulmonary fibrosis by modulating HMGB1/RAGE pathway.Toxicol Appl Pharmacol. 2015 Feb 15;283(1):50-6. doi: 10.1016/j.taap.2015.01.001. Epub 2015 Jan 9.
|
291 |
Dysregulated Lung Commensal Bacteria Drive Interleukin-17B Production to Promote Pulmonary Fibrosis through Their Outer Membrane Vesicles.Immunity. 2019 Mar 19;50(3):692-706.e7. doi: 10.1016/j.immuni.2019.02.001. Epub 2019 Feb 26.
|
292 |
Expression of HIF-1A/VEGF/ING-4 Axis in Pulmonary Sarcoidosis.Adv Exp Med Biol. 2015;866:61-9. doi: 10.1007/5584_2015_144.
|
293 |
The MUC5B promoter polymorphism is associated with idiopathic pulmonary fibrosis in a Mexican cohort but is rare among Asian ancestries.Chest. 2015 Feb;147(2):460-464. doi: 10.1378/chest.14-0867.
|
294 |
Herbal decoctosome is a novel form of medicine.Sci China Life Sci. 2019 Mar;62(3):333-348. doi: 10.1007/s11427-018-9508-0. Epub 2019 Mar 21.
|
295 |
The Role of KCNMB1 and BK Channels in Myofibroblast Differentiation and Pulmonary Fibrosis.Am J Respir Cell Mol Biol. 2020 Feb;62(2):191-203. doi: 10.1165/rcmb.2019-0163OC.
|
296 |
Nrf2 amplifies oxidative stress via induction of Klf9.Mol Cell. 2014 Mar 20;53(6):916-928. doi: 10.1016/j.molcel.2014.01.033. Epub 2014 Mar 6.
|
297 |
Laminin 1 is a genetic modifier of TGF-1-stimulated pulmonary fibrosis.JCI Insight. 2018 Sep 20;3(18):e99574. doi: 10.1172/jci.insight.99574. eCollection 2018 Sep 20.
|
298 |
Identification and Optimization of Mechanism-Based Fluoroallylamine Inhibitors of Lysyl Oxidase-like 2/3.J Med Chem. 2019 Nov 14;62(21):9874-9889. doi: 10.1021/acs.jmedchem.9b01283. Epub 2019 Oct 16.
|
299 |
Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.Nat Commun. 2019 Jul 29;10(1):3390. doi: 10.1038/s41467-019-11327-1.
|
300 |
TRAIL signals through the ubiquitin ligase MID1 to promote pulmonary fibrosis.BMC Pulm Med. 2019 Feb 7;19(1):31. doi: 10.1186/s12890-019-0786-x.
|
301 |
Matrix metalloproteinase-19 is a key regulator of lung fibrosis in mice and humans.Am J Respir Crit Care Med. 2012 Oct 15;186(8):752-62. doi: 10.1164/rccm.201202-0302OC. Epub 2012 Aug 2.
|
302 |
Identification of MMP28 as a biomarker for the differential diagnosis of idiopathic pulmonary fibrosis.PLoS One. 2018 Sep 12;13(9):e0203779. doi: 10.1371/journal.pone.0203779. eCollection 2018.
|
303 |
Developmental pathways in the pathogenesis of lung fibrosis.Mol Aspects Med. 2019 Feb;65:56-69. doi: 10.1016/j.mam.2018.08.004. Epub 2018 Aug 23.
|
304 |
Amplified canonical transforming growth factor- signalling via heat shock protein 90 in pulmonary fibrosis.Eur Respir J. 2017 Feb 23;49(2):1501941. doi: 10.1183/13993003.01941-2015. Print 2017 Feb.
|
305 |
Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis.J Clin Invest. 2013 Mar;123(3):1096-108. doi: 10.1172/JCI66700. Epub 2013 Feb 22.
|
306 |
Transplantation of adipose-derived mesenchymal stem cells attenuates pulmonary fibrosis of silicosis via anti-inflammatory and anti-apoptosis effects in rats.Stem Cell Res Ther. 2018 Apr 19;9(1):110. doi: 10.1186/s13287-018-0846-9.
|
307 |
Attenuated pulmonary fibrosis in sialidase-3 knockout (Neu3(-/-)) mice.Am J Physiol Lung Cell Mol Physiol. 2020 Jan 1;318(1):L165-L179. doi: 10.1152/ajplung.00275.2019. Epub 2019 Oct 16.
|
308 |
Ninjurin1 Plays a Crucial Role in Pulmonary Fibrosis by Promoting Interaction between Macrophages and Alveolar Epithelial Cells.Sci Rep. 2018 Dec 3;8(1):17542. doi: 10.1038/s41598-018-35997-x.
|
309 |
Nkx2.5/Csx represses myofibroblast differentiation.Am J Respir Cell Mol Biol. 2010 Feb;42(2):218-26. doi: 10.1165/rcmb.2008-0404OC. Epub 2009 Apr 24.
|
310 |
Role of Nephronectin in Pathophysiology of Silicosis.Int J Mol Sci. 2019 May 26;20(10):2581. doi: 10.3390/ijms20102581.
|
311 |
Tenofovir alafenamide fumarate attenuates bleomycin-induced pulmonary fibrosis by upregulating the NS5ATP9 and TGF-1/Smad3 signaling pathway.Respir Res. 2019 Jul 22;20(1):163. doi: 10.1186/s12931-019-1102-2.
|
312 |
PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis.Cell Mol Life Sci. 2019 Dec;76(23):4783-4794. doi: 10.1007/s00018-019-03133-1. Epub 2019 Jun 5.
|
313 |
Anti-inflammatory and anti-fibrotic effects of intravenous adipose-derived stem cell transplantation in a mouse model of bleomycin-induced interstitial pneumonia.Sci Rep. 2017 Nov 6;7(1):14608. doi: 10.1038/s41598-017-15022-3.
|
314 |
PINK1 attenuates mtDNA release in alveolar epithelial cells and TLR9 mediated profibrotic responses.PLoS One. 2019 Jun 6;14(6):e0218003. doi: 10.1371/journal.pone.0218003. eCollection 2019.
|
315 |
Histological hallmarks and role of Slug/PIP axis in pulmonary hypertension secondary to pulmonary fibrosis.EMBO Mol Med. 2019 Sep;11(9):e10061. doi: 10.15252/emmm.201810061. Epub 2019 Aug 29.
|
316 |
Plexin C1 deficiency permits synaptotagmin 7-mediated macrophage migration and enhances mammalian lung fibrosis.FASEB J. 2016 Dec;30(12):4056-4070. doi: 10.1096/fj.201600373R. Epub 2016 Sep 8.
|
317 |
Transcriptional regulatory model of fibrosis progression in the human lung.JCI Insight. 2019 Nov 14;4(22):e131597. doi: 10.1172/jci.insight.131597.
|
318 |
CircRNA-012091/PPP1R13B-mediated Lung Fibrotic Response in Silicosis via Endoplasmic Reticulum Stress and Autophagy.Am J Respir Cell Mol Biol. 2019 Sep;61(3):380-391. doi: 10.1165/rcmb.2019-0017OC.
|
319 |
Citrus Alkaline Extract Delayed the Progression of Pulmonary Fibrosis by Inhibiting p38/NF-B Signaling Pathway-Induced Cell Apoptosis.Evid Based Complement Alternat Med. 2019 Feb 4;2019:1528586. doi: 10.1155/2019/1528586. eCollection 2019.
|
320 |
Wedelolactone Attenuates Pulmonary Fibrosis Partly Through Activating AMPK and Regulating Raf-MAPKs Signaling Pathway.Front Pharmacol. 2019 Mar 5;10:151. doi: 10.3389/fphar.2019.00151. eCollection 2019.
|
321 |
Expression of Peroxiredoxins and Pulmonary Surfactant Protein A Induced by Silica in Rat Lung Tissue.Biomed Environ Sci. 2016 Aug;29(8):584-588. doi: 10.3967/bes2016.077.
|
322 |
The role of pentraxin-3 as a prognostic biomarker in paraquat poisoning.Toxicol Lett. 2012 Jul 20;212(2):157-60. doi: 10.1016/j.toxlet.2011.12.007. Epub 2011 Dec 22.
|
323 |
Rac2 is required for alternative macrophage activation and bleomycin induced pulmonary fibrosis; a macrophage autonomous phenotype.PLoS One. 2017 Aug 17;12(8):e0182851. doi: 10.1371/journal.pone.0182851. eCollection 2017.
|
324 |
Regulation of myofibroblast differentiation and bleomycin-induced pulmonary fibrosis by adrenomedullin.Am J Physiol Lung Cell Mol Physiol. 2013 Jun 1;304(11):L757-64. doi: 10.1152/ajplung.00262.2012. Epub 2013 Apr 12.
|
325 |
lncRNAPCAT29 inhibits pulmonary fibrosis via the TGF?regulated RASAL1/ERK1/2 signal pathway.Mol Med Rep. 2018 Jun;17(6):7781-7788. doi: 10.3892/mmr.2018.8807. Epub 2018 Mar 28.
|
326 |
Hypocrea peltata: a mycological Dr Jekyll and Mr Hyde?.Mycologia. 2011 May-Jun;103(3):616-30. doi: 10.3852/10-227. Epub 2011 Jan 24.
|
327 |
Reticulocalbin 3 Deficiency in Alveolar Epithelium Exacerbated Bleomycin-induced Pulmonary Fibrosis.Am J Respir Cell Mol Biol. 2018 Sep;59(3):320-333. doi: 10.1165/rcmb.2017-0347OC.
|
328 |
FIZZ2/RELM- induction and role in pulmonary fibrosis.J Immunol. 2011 Jul 1;187(1):450-61. doi: 10.4049/jimmunol.1000964. Epub 2011 May 20.
|
329 |
The novel inhibitor PRI-724 for Wnt/-catenin/CBP signaling ameliorates bleomycin-induced pulmonary fibrosis in mice.Exp Lung Res. 2019 Sep;45(7):188-199. doi: 10.1080/01902148.2019.1638466. Epub 2019 Jul 12.
|
330 |
Reactive oxygen species modulator 1 regulates oxidative stress and induces renal and pulmonary fibrosis in a unilateral ureteral obstruction rat model and in HK? cells.Mol Med Rep. 2017 Oct;16(4):4855-4862. doi: 10.3892/mmr.2017.7161. Epub 2017 Aug 3.
|
331 |
Early upregulation of acute respiratory distress syndrome-associated cytokines promotes lethal disease in an aged-mouse model of severe acute respiratory syndrome coronavirus infection.J Virol. 2009 Jul;83(14):7062-74. doi: 10.1128/JVI.00127-09. Epub 2009 May 6.
|
332 |
Secretoglobin 3A2 suppresses bleomycin-induced pulmonary fibrosis by transforming growth factor beta signaling down-regulation.J Biol Chem. 2011 Jun 3;286(22):19682-92. doi: 10.1074/jbc.M111.239046. Epub 2011 Apr 10.
|
333 |
Syndecan-4 Inhibits the Development of Pulmonary Fibrosis by Attenuating TGF- Signaling.Int J Mol Sci. 2019 Oct 9;20(20):4989. doi: 10.3390/ijms20204989.
|
334 |
Semaphorin 4A enhances lung fibrosis through activation of Akt via PlexinD1 receptor.J Biosci. 2015 Dec;40(5):855-62. doi: 10.1007/s12038-015-9566-9.
|
335 |
Endogenous Semaphorin-7A Impedes Human Lung Fibroblast Differentiation.PLoS One. 2017 Jan 17;12(1):e0170207. doi: 10.1371/journal.pone.0170207. eCollection 2017.
|
336 |
Hematopoietic protease nexin-1 protects against lung injury by preventing thrombin signaling in mice.Blood Adv. 2018 Sep 25;2(18):2389-2399. doi: 10.1182/bloodadvances.2018018283.
|
337 |
Epigallocatechin-3-gallate (EGCG) inhibits aggregation of pulmonary fibrosis associated mutant surfactant protein A2 via a proteasomal degradation pathway.Int J Biochem Cell Biol. 2019 Nov;116:105612. doi: 10.1016/j.biocel.2019.105612. Epub 2019 Sep 20.
|
338 |
Invitro expansion of endogenous human alveolar epithelial type II cells in fibroblast-free spheroid culture.Biochem Biophys Res Commun. 2019 Aug 6;515(4):579-585. doi: 10.1016/j.bbrc.2019.05.187. Epub 2019 Jun 6.
|
339 |
Sirtuin 7 is decreased in pulmonary fibrosis and regulates the fibrotic phenotype of lung fibroblasts.Am J Physiol Lung Cell Mol Physiol. 2017 Jun 1;312(6):L945-L958. doi: 10.1152/ajplung.00473.2016. Epub 2017 Apr 6.
|
340 |
Abrogation of transforming growth factor--induced tissue fibrosis in TBRIcaCol1a2Cre transgenic mice by the second generation tyrosine kinase inhibitor SKI-606 (Bosutinib).PLoS One. 2018 May 2;13(5):e0196559. doi: 10.1371/journal.pone.0196559. eCollection 2018.
|
341 |
Docosahexaenoic acid (DHA) ameliorates paraquat-induced pulmonary fibrosis in rats possibly through up-regulation of Smad 7 and SnoN.Food Chem Toxicol. 2013 Jul;57:330-7. doi: 10.1016/j.fct.2013.03.045. Epub 2013 Apr 13.
|
342 |
Protective effects of GHK-Cu in bleomycin-induced pulmonary fibrosis via anti-oxidative stress and anti-inflammation pathways.Life Sci. 2020 Jan 15;241:117139. doi: 10.1016/j.lfs.2019.117139. Epub 2019 Dec 4.
|
343 |
Effects of curcumin on artery blood gas index of rats with pulmonary fibrosis caused by paraquat poisoning and the expression of Smad 4, Smurf 2, interleukin-4 and interferon-.Exp Ther Med. 2019 May;17(5):3664-3670. doi: 10.3892/etm.2019.7341. Epub 2019 Mar 4.
|
344 |
Suppression of SMOC2 reduces bleomycin (BLM)-induced pulmonary fibrosis by inhibition of TGF-1/SMADs pathway.Biomed Pharmacother. 2018 Sep;105:841-847. doi: 10.1016/j.biopha.2018.03.058. Epub 2018 Jun 18.
|
345 |
Cell-penetrating peptides selectively targeting SMAD3 inhibit profibrotic TGF- signaling.J Clin Invest. 2017 Jun 30;127(7):2541-2554. doi: 10.1172/JCI88696. Epub 2017 May 22.
|
346 |
Imbalance in the pro-hepatocyte growth factor activation system in bleomycin-induced lung fibrosis in mice.Am J Respir Cell Mol Biol. 2010 Mar;42(3):286-93. doi: 10.1165/rcmb.2008-0305OC. Epub 2009 May 15.
|
347 |
Epimorphin expression in interstitial pneumonia.Respir Res. 2005 Jan 16;6(1):6. doi: 10.1186/1465-9921-6-6.
|
348 |
Epigenetic regulation of cyclooxygenase-2 by methylation of c8orf4 in pulmonary fibrosis.Clin Sci (Lond). 2016 Apr;130(8):575-86. doi: 10.1042/CS20150697. Epub 2016 Jan 7.
|
349 |
Up-regulation of THY1 attenuates interstitial pulmonary fibrosis and promotes lung fibroblast apoptosis during acute interstitial pneumonia by blockade of the WNT signaling pathway.Cell Cycle. 2019 Mar-Apr;18(6-7):670-681. doi: 10.1080/15384101.2019.1578144. Epub 2019 Mar 4.
|
350 |
P27 Promotes TGF--Mediated Pulmonary Fibrosis via Interacting with MTORC2.Can Respir J. 2019 Sep 19;2019:7157861. doi: 10.1155/2019/7157861. eCollection 2019.
|
351 |
TM4SF5-mediated CD44v8-10 splicing variant promotes survival of type II alveolar epithelial cells during idiopathic pulmonary fibrosis.Cell Death Dis. 2019 Sep 9;10(9):645. doi: 10.1038/s41419-019-1878-5.
|
352 |
Transmembrane protease, serine 4 (TMPRSS4) is upregulated in IPF lungs and increases the fibrotic response in bleomycin-induced lung injury.PLoS One. 2018 Mar 12;13(3):e0192963. doi: 10.1371/journal.pone.0192963. eCollection 2018.
|
353 |
The KCa3.1 blocker TRAM-34 inhibits proliferation of fibroblasts in paraquat-induced pulmonary fibrosis.Toxicol Lett. 2018 Oct 1;295:408-415. doi: 10.1016/j.toxlet.2018.07.020. Epub 2018 Jul 20.
|
354 |
Expression of TRB3 promotes epithelialmesenchymal transition of MLE?2 murine alveolar type II epithelial cells through the TGF?/Smad3 signaling pathway.Mol Med Rep. 2019 Apr;19(4):2869-2875. doi: 10.3892/mmr.2019.9900. Epub 2019 Jan 28.
|
355 |
Positional cloning reveals strain-dependent expression of Trim16 to alter susceptibility to bleomycin-induced pulmonary fibrosis in mice.PLoS Genet. 2013;9(1):e1003203. doi: 10.1371/journal.pgen.1003203. Epub 2013 Jan 17.
|
356 |
Loss-of-function mutations in the RNA biogenesis factor NAF1 predispose to pulmonary fibrosis-emphysema. Sci Transl Med. 2016 Aug 10;8(351):351ra107. doi: 10.1126/scitranslmed.aaf7837.
|
|
|
|
|
|
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