General Information of Disease (ID: DISB3X5A)

Disease Name Nervous system inflammation
Synonyms central nervous system inflammation; inflammation of central nervous system; encephalitis and/or myelitis; encephalitis &/or myelitis
Disease Class 1D0Y: CNS non-viral infection
Definition Inflammation of the brain and the spinal cord.
Disease Hierarchy
DIS184KT: Skin inflammation
DISEP2HK: Central and peripheral nervous disease
DISWD40R: Disease
DISB3X5A: Nervous system inflammation
ICD Code
ICD-11
ICD-11: 1D0Y
Disease Identifiers
MONDO ID
MONDO_0005156
MESH ID
D004679
UMLS CUI
C0014070
MedGen ID
8603
SNOMED CT ID
62950007

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
5-LO (pain/neuro-inflammation), St Charles Pharmaceuticals DMF2OT4 Investigative NA [1]
AV-1013 DM7L37I Investigative NA [1]
KR-31360 DMUR8MP Investigative NA [1]
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Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 176 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABL2 TT1A6HL Limited Biomarker [2]
ADRA2A TTWG9A4 Limited Biomarker [3]
AOC3 TT7HC21 Limited Altered Expression [4]
ARRB1 TTMVD4A Limited Altered Expression [5]
ARRB2 TT8SO2I Limited Biomarker [6]
BACE1 TTJUNZF Limited Biomarker [7]
C3AR1 TTI6B3F Limited Biomarker [8]
CBL TT7QT13 Limited Biomarker [9]
CBLB TTHRAIJ Limited Biomarker [10]
CD2 TTJDUNO Limited Biomarker [11]
CD274 TT8ZLTI Limited Biomarker [12]
CD40LG TTIJP3Q Limited Biomarker [13]
CD83 TTT9MRQ Limited Biomarker [14]
CDK19 TTNABU9 Limited Biomarker [15]
CHAT TTKYFSB Limited Biomarker [16]
CSNK2A1 TTER6YH Limited Biomarker [17]
DGAT1 TT0GV3R Limited Biomarker [18]
DRD5 TTS2PH3 Limited Biomarker [19]
FCGR2B TT5RWKQ Limited Altered Expression [20]
FTH1 TT975ZT Limited Altered Expression [21]
GALR2 TTBPW3J Limited Altered Expression [22]
GCK TTDLNGZ Limited Biomarker [23]
GOT1 TTU507L Limited Biomarker [24]
GP6 TTTJUVZ Limited Biomarker [25]
GPR17 TTMPART Limited Biomarker [26]
HRH1 TTTIBOJ Limited Biomarker [27]
HRH2 TTQHJ1K Limited Biomarker [28]
HRH3 TT9JNIC Limited Genetic Variation [29]
IKZF2 TTKT5NV Limited Altered Expression [30]
IL11RA TTZPLJS Limited Biomarker [31]
IL17D TTC5LTG Limited Biomarker [32]
ILDR2 TT0R2QD Limited Biomarker [33]
IRAK3 TTBPJOK Limited Altered Expression [34]
KCNK3 TTGR91N Limited Altered Expression [35]
KCNK9 TTL4FMB Limited Altered Expression [35]
LIFR TTID542 Limited Altered Expression [36]
LY75 TTG180Q Limited Biomarker [37]
MAP4K3 TTI0AHJ Limited Biomarker [23]
MC1R TT0MV2T Limited Biomarker [38]
NOD1 TTYSRXM Limited Altered Expression [39]
P2RY12 TTZ1DT0 Limited Altered Expression [40]
PDE7A TT1BC3A Limited Altered Expression [41]
PKN2 TTTHO0M Limited Genetic Variation [42]
PPID TTNAFOU Limited Biomarker [43]
PPIF TTRFQTB Limited Biomarker [43]
PRKCQ TT1MS7X Limited Biomarker [44]
RGMA TTURJV4 Limited Biomarker [45]
SIRPA TTBRJS9 Limited Biomarker [46]
SLAMF6 TTSIYJ6 Limited Biomarker [47]
SLC18A3 TTV8KWS Limited Altered Expression [48]
SLC6A1 TTPRKM0 Limited Biomarker [49]
SLC6A11 TT8RXO5 Limited Altered Expression [50]
SLC9A3 TTFZVPO Limited Biomarker [51]
SPP1 TT8ME6I Limited Biomarker [52]
TIAM1 TTNU6I5 Limited Altered Expression [53]
TNFRSF13B TTL9OD4 Limited Biomarker [54]
VSIR TT51SK8 Limited Altered Expression [55]
MADCAM1 TTBD6I7 Disputed Biomarker [56]
CD24 TTCTYNP moderate Biomarker [57]
CRYAB TT7RUHB moderate Biomarker [58]
ITGAM TTB69FJ moderate Biomarker [59]
MS4A1 TTUE541 moderate Biomarker [60]
P2RX7 TT473XN moderate Altered Expression [40]
PDXP TT9UYG4 moderate Biomarker [61]
PRDX5 TTLPJWH moderate Biomarker [61]
PTPRC TTUS45N moderate Altered Expression [62]
TNFRSF1B TT63WSF moderate Altered Expression [63]
TSPO TTPTXIN moderate Genetic Variation [64]
VCAM1 TTHCEF6 moderate Altered Expression [65]
ACKR1 TTKY2NS Strong Biomarker [66]
ADCYAP1R1 TT5OREU Strong Biomarker [67]
AICDA TTKRTP6 Strong Biomarker [68]
AIF1 TT12MEP Strong Biomarker [69]
ALCAM TT2AFT6 Strong Biomarker [70]
ARG1 TT7ZQEV Strong Biomarker [71]
ARG2 TTV1AG6 Strong Altered Expression [72]
C5 TTKANGO Strong Biomarker [73]
C5AR1 TTHXFA1 Strong Biomarker [73]
CCL22 TTBTWI1 Strong Biomarker [74]
CCL3 TT8I4WB Strong Altered Expression [75]
CCR2 TTFZYTO Strong Biomarker [76]
CCR6 TTFDB30 Strong Altered Expression [77]
CCR9 TTIPS8B Strong Biomarker [56]
CD200 TT0BE68 Strong Biomarker [78]
CD28 TTQ13FT Strong Biomarker [79]
CD40 TT1ERKL Strong Biomarker [13]
CD47 TT28S46 Strong Biomarker [80]
CD58 TT5KSBY Strong Biomarker [81]
CD86 TT53XHB Strong Biomarker [82]
CLEC12A TT70N8V Strong Biomarker [83]
CMKLR1 TT4UGZL Strong Biomarker [84]
CTSC TT4H0V2 Strong Biomarker [85]
CTSE TTLXC4Q Strong Biomarker [86]
CTSH TT3G406 Strong Biomarker [87]
CX3CR1 TT2T98G Strong Biomarker [88]
CXCL13 TT0NIZ1 Strong Biomarker [89]
CXCR2 TT30C9G Strong Biomarker [90]
CYBB TT5T8MR Strong Genetic Variation [91]
CYP46A1 TT4EB85 Strong Biomarker [92]
DPYSL2 TTZCW3T Strong Altered Expression [93]
DUSP10 TTF3RJ0 Strong Altered Expression [94]
EGFL7 TT7WD0H Strong Altered Expression [95]
ENTPD1 TTYM8DJ Strong Biomarker [71]
FOXP3 TT1X3QF Strong Biomarker [96]
GAP43 TTSGLN5 Strong Altered Expression [97]
GFAP TTI6FFX Strong Biomarker [98]
GJB1 TTSJIRP Strong Biomarker [99]
GJB6 TTAU8SJ Strong Biomarker [100]
GPI TT19JIZ Strong Biomarker [101]
GPR183 TTME5YJ Strong Biomarker [102]
GRIA4 TTPJR0G Strong Biomarker [103]
GRM1 TTVBPDM Strong Altered Expression [104]
GRM4 TTICZ1O Strong Biomarker [103]
GRM5 TTHS256 Strong Altered Expression [104]
HNRNPA1 TTPJ9XK Strong Biomarker [105]
IFNAR1 TTSYFMA Strong Biomarker [106]
IFNB1 TT4TZ8J Strong Biomarker [107]
IL11 TTGUYTR Strong Biomarker [108]
IL17F TT2B6PS Strong Biomarker [109]
IL23R TT6H4QR Strong Biomarker [110]
IL37 TTQTX98 Strong Biomarker [111]
IL7R TTAWI51 Strong Biomarker [112]
IRF3 TTYR7OH Strong Altered Expression [87]
ITGA4 TTJMF9P Strong Biomarker [113]
ITGAL TT48WR6 Strong Biomarker [114]
ITGB2 TTIJWR7 Strong Biomarker [114]
KLK6 TTLPF4X Strong Biomarker [115]
KLK8 TTH5MRS Strong Biomarker [116]
LANCL1 TTZW8NS Strong Biomarker [111]
LBP TTVQJLY Strong Altered Expression [117]
LINGO1 TTZYQ80 Strong Biomarker [118]
LTBR TTFO0PM Strong Biomarker [119]
MBTPS1 TTNSM2I Strong Biomarker [120]
MMP12 TTXZ0KQ Strong Biomarker [121]
NCF1 TTZ4JC3 Strong Altered Expression [21]
NR4A1 TTMXE2Q Strong Biomarker [122]
NR4A2 TT9HKN3 Strong Altered Expression [123]
NTF3 TTZHKV9 Strong Altered Expression [124]
NTN1 TT0AH4L Strong Altered Expression [125]
P2RX4 TT1NLOA Strong Altered Expression [40]
PCSK1 TTED9LZ Strong Biomarker [126]
PDE4B TTVIAT9 Strong Biomarker [127]
PECAM1 TT4EZB2 Strong Altered Expression [128]
PLA2G4A TTT1JVS Strong Biomarker [129]
PRMT5 TTR1D7X Strong Biomarker [130]
PROC TTZUXYS Strong Altered Expression [131]
PSMB9 TTOUSTQ Strong Altered Expression [132]
PTBP1 TTWMX0U Strong Biomarker [105]
PTGES TTYLQ8V Strong Biomarker [133]
RIPK2 TTCQ2E5 Strong Biomarker [134]
RPSA TTLUW5B Strong Biomarker [111]
SLC7A11 TTBZMIO Strong Altered Expression [135]
SMPD1 TTJTM88 Strong Biomarker [136]
SORT1 TTRX9AV Strong Biomarker [137]
SRR TTZFUY6 Strong Biomarker [138]
STK38 TT27XFN Strong Biomarker [139]
SYVN1 TT8XKYM Strong Biomarker [140]
TDO2 TTXNCBV Strong Altered Expression [141]
TLR8 TT8CWFK Strong Altered Expression [142]
TNFRSF4 TTL31H0 Strong Biomarker [143]
TNFSF13B TTWMIDN Strong Biomarker [54]
TRPM4 TTJ2HKA Strong Biomarker [144]
TRPM8 TTXDKTO Strong Biomarker [145]
ULK1 TT4D7MJ Strong Biomarker [146]
VEGFB TTPJQHE Strong Biomarker [147]
CD52 TTQT5S9 Definitive Altered Expression [148]
CHRM3 TTQ13Z5 Definitive Genetic Variation [64]
IL7 TT8FRMO Definitive Altered Expression [149]
IL9 TT0JTFD Definitive Biomarker [150]
LIF TTGZ5WN Definitive Biomarker [151]
MALT1 TTCI81G Definitive Altered Expression [152]
RTN4R TTVRZUO Definitive Biomarker [153]
S1PR1 TT9JZCK Definitive Genetic Variation [154]
SGK1 TTTV8EJ Definitive Altered Expression [155]
SPHK1 TTOHFIY Definitive Biomarker [156]
TLR7 TTRJ1K4 Definitive Biomarker [157]
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⏷ Show the Full List of 176 DTT(s)
This Disease Is Related to 6 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
KCNK2 DTENHUP Limited Biomarker [158]
SLC22A17 DTXI9E6 Limited Altered Expression [159]
SLC6A13 DTX8KP0 Limited Altered Expression [50]
SLC7A10 DTVL2JY Limited Biomarker [160]
SLC25A14 DTHSNUW Strong Altered Expression [161]
SLC25A27 DT0HW5C Strong Altered Expression [161]
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⏷ Show the Full List of 6 DTP(s)
This Disease Is Related to 6 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ADH5 DEIOH6A Limited Biomarker [162]
HINT1 DEWJATF Limited Biomarker [163]
PGPEP1 DEVDR46 Limited Biomarker [164]
GLS DE3E0VT Strong Biomarker [165]
TGM6 DEUWCVD Strong Altered Expression [166]
GANAB DEMWKYT Definitive Biomarker [167]
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⏷ Show the Full List of 6 DME(s)
This Disease Is Related to 185 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACKR2 OTWYY14H Limited Biomarker [168]
ADGRG3 OTB3XFA1 Limited Biomarker [169]
AIMP1 OTTA5C3U Limited Biomarker [170]
ANKRD55 OT62KZII Limited Biomarker [171]
ASPRV1 OT8WVIBW Limited Biomarker [172]
BCAP31 OTKSACR4 Limited Altered Expression [173]
BHMT OTYB6PXZ Limited Altered Expression [30]
BTN2A2 OTUOAJZA Limited Biomarker [174]
C1QTNF6 OT57EPQC Limited Biomarker [175]
CALB2 OTSNMCG9 Limited Biomarker [176]
CBLIF OTNE20WU Limited Biomarker [177]
CCL1 OT23NON8 Limited Genetic Variation [178]
CCL25 OTLWJ8CJ Limited Biomarker [179]
CCL4L2 OTDBSXOU Limited Genetic Variation [178]
CCRL2 OT5PX0RX Limited Biomarker [168]
CD99L2 OTQTZFCX Limited Biomarker [180]
CDKN2D OT2TTZPZ Limited Biomarker [181]
CDR2 OTD3ZJST Limited Biomarker [182]
CH25H OT9S2BSW Limited Genetic Variation [183]
CIITA OTRJNZFO Limited Biomarker [184]
COIL OTP4I4DL Limited Biomarker [185]
CRACR2A OTJUGSVE Limited Biomarker [186]
CUL9 OTPUCLZT Limited Biomarker [187]
CXXC1 OTO10D1N Limited Genetic Variation [188]
CYBA OT16N9ZO Limited Altered Expression [21]
DCX OTISR7K3 Limited Altered Expression [176]
DEGS1 OT4WXPKW Limited Biomarker [189]
DNALI1 OTTB3L8N Limited Altered Expression [173]
DUSP14 OTGODFCR Limited Biomarker [190]
EGR2 OTAVQ78J Limited Altered Expression [191]
ELAVL3 OTI2VI8B Limited Biomarker [192]
ENTPD2 OTZ2PKPM Limited Biomarker [193]
FUT7 OTJF6BSN Limited Biomarker [194]
FUT8 OTJJCVG1 Limited Biomarker [195]
GOSR1 OTX8TMVU Limited Altered Expression [173]
HECTD3 OTTGP4OK Limited Biomarker [152]
HEPH OTZ2F15Z Limited Altered Expression [21]
HIP1R OTIPKEJC Limited Biomarker [196]
HLA-DRB5 OTUX5TWM Limited Biomarker [197]
HPX OT14T7Q1 Limited Biomarker [198]
IL17RC OTEFOBSS Limited Biomarker [109]
IL27 OTIS3OF8 Limited Biomarker [32]
IL27RA OTSQBAKI Limited Biomarker [199]
IL9R OTILCLXA Limited Altered Expression [200]
JAM2 OTHVJJRJ Limited Biomarker [201]
LAMTOR1 OTIBJBW9 Limited Biomarker [202]
LGALS4 OTKQCG0H Limited Biomarker [203]
LLGL1 OTAIQSXZ Limited Biomarker [204]
MAP1B OTVXW089 Limited Biomarker [205]
MAST2 OT85GLPP Limited Altered Expression [187]
MINK1 OTKB0RA8 Limited Biomarker [206]
NCR3 OT20M764 Limited Biomarker [207]
NDST1 OT9E10W2 Limited Altered Expression [208]
NFE2L1 OT1QHOS2 Limited Altered Expression [209]
NRF1 OTOXWNV8 Limited Altered Expression [209]
PADI2 OTT40K94 Limited Biomarker [210]
PDK4 OTCMHMBZ Limited Altered Expression [211]
PDP2 OTADNMGK Limited Altered Expression [212]
PELI1 OTMLBCLC Limited Biomarker [213]
PGAM5 OT6Q5M0C Limited Altered Expression [214]
PIAS4 OTB7SVMZ Limited Genetic Variation [215]
PIK3AP1 OTMW1B47 Limited Biomarker [216]
PNMA1 OTEUG8RL Limited Biomarker [217]
POLR1D OTOCZQNA Limited Altered Expression [218]
POU2AF1 OTOO6WHL Limited Biomarker [219]
PPP1R11 OTSHYPPW Limited Biomarker [220]
PPP1R15A OTYG179K Limited Biomarker [221]
PSME3 OTSTC4YY Limited Biomarker [222]
RAB5A OTFR2KM4 Limited Altered Expression [146]
RASA3 OT9C54MN Limited Biomarker [223]
RBM45 OTWTHD77 Limited Biomarker [224]
RFX1 OTZUDMPR Limited Biomarker [225]
RRN3 OTKGOZ49 Limited Altered Expression [218]
SCNN1A OTE2KVZV Limited Biomarker [51]
SEMA6B OT3VVVUO Limited Altered Expression [119]
SLAMF9 OTH1OGZW Limited Biomarker [226]
SNCB OTELSEK6 Limited Biomarker [227]
SOCS2 OTBPNKJQ Limited Altered Expression [228]
ST3GAL4 OTNENJZQ Limited Biomarker [189]
STK24 OTGUHOIL Limited Biomarker [229]
STOML3 OTLQGALK Limited Biomarker [230]
SUMO3 OTTUJQJ1 Limited Genetic Variation [215]
SYN2 OTK0DEGH Limited Altered Expression [231]
THYN1 OTMRKMPD Limited Biomarker [232]
TMED5 OT70W1J8 Limited Altered Expression [173]
TNFRSF19 OTTVT4MB Limited Biomarker [153]
TRIP4 OTA8OASA Limited Biomarker [160]
AHSA1 OTC7AFHT moderate Altered Expression [233]
ATN1 OTNZFLKY moderate Biomarker [33]
CD1D OT3ROU4J moderate Altered Expression [234]
GRAP2 OTS5NIZ3 moderate Altered Expression [233]
KRT20 OT4RB40L moderate Biomarker [60]
POLDIP2 OT8SZSJ6 moderate Altered Expression [233]
PTHLH OTI1JF13 moderate Biomarker [61]
RNF19A OTKWCV80 moderate Altered Expression [233]
AIM2 OT86QUI8 Strong Biomarker [235]
AMIGO2 OTPAIT1O Strong Biomarker [236]
ARHGEF2 OTBQTFRT Strong Biomarker [111]
ARMH1 OTTJC0D6 Strong Biomarker [111]
ARNT2 OTAQD3YV Strong Biomarker [237]
ATP2B2 OT1NPZ9T Strong Biomarker [238]
AVIL OTUK67IT Strong Biomarker [239]
BHLHE40 OTITX14U Strong Biomarker [240]
CCDC134 OT70OQQV Strong Altered Expression [241]
CCL26 OT2B7HR9 Strong Biomarker [242]
CD200R1 OT65Q9M6 Strong Altered Expression [243]
CD226 OT4UG0KB Strong Biomarker [244]
CD48 OT83ZNPP Strong Biomarker [81]
CD93 OT6HZT6H Strong Biomarker [245]
CDCP1 OTD7RRWK Strong Biomarker [246]
CEMIP OTK80FYN Strong Biomarker [247]
CERS2 OTRAHYYP Strong Biomarker [248]
CERS6 OTOP4GV1 Strong Biomarker [249]
CLDN11 OTNN6UTL Strong Altered Expression [250]
CLDN3 OT71MN9S Strong Biomarker [251]
CPT1A OTI862QH Strong Genetic Variation [252]
CTSZ OTSCX2LL Strong Altered Expression [253]
DNAJC5 OTCZDXAL Strong Biomarker [254]
DOCK8 OTNQLL21 Strong Biomarker [255]
DUSP2 OTH54FMR Strong Biomarker [67]
EBNA1BP2 OTBRVMZH Strong Biomarker [111]
EIF1 OTB4GZ0V Strong Biomarker [138]
EOMES OTB9VQFA Strong Altered Expression [256]
FABP7 OTRE2H4G Strong Biomarker [257]
FADD OTV7GFHH Strong Biomarker [258]
FANCC OTTIDM3P Strong Genetic Variation [259]
FYB1 OT6345CH Strong Biomarker [260]
GPR65 OTCF5O4G Strong Altered Expression [261]
GSDMD OTH39BKI Strong Biomarker [262]
HAVCR2 OTOL603T Strong Biomarker [263]
HBD OTRQG4WA Strong Altered Expression [264]
ICAM5 OTDGGAFH Strong Biomarker [114]
IFNA1 OTPMKY0L Strong Biomarker [265]
IL17RA OTVVI8ER Strong Biomarker [266]
IRGM OTKD3O5Z Strong Biomarker [267]
ISG20 OTCWRJJW Strong Biomarker [268]
ITGAX OTOGIMHE Strong Altered Expression [20]
KDM6A OTZM3MJJ Strong Biomarker [269]
KLK10 OTD573EL Strong Biomarker [116]
LGALS8 OT71LJ8T Strong Biomarker [270]
LILRA1 OTZ4NA7Q Strong Biomarker [271]
LRCH1 OT0RCL85 Strong Biomarker [255]
MAK16 OTD546E5 Strong Biomarker [105]
MAVS OTTQ0J64 Strong Biomarker [129]
MCF2L2 OTOGFMIH Strong Biomarker [272]
MZB1 OT071TET Strong Biomarker [67]
NPAS4 OTA3HH6W Strong Altered Expression [237]
OCLN OTSUTVWL Strong Biomarker [273]
OLIG1 OTIMFI31 Strong Biomarker [274]
OLIG2 OTMCN6D3 Strong Biomarker [275]
OMP OT7JH0DY Strong Biomarker [230]
OTUB1 OT8WWM9O Strong Biomarker [276]
PANX1 OTXPEDOK Strong Biomarker [277]
PCBP1 OTHN0TD7 Strong Biomarker [278]
PIMREG OTKC8T3E Strong Biomarker [279]
PNO1 OT010GIS Strong Biomarker [105]
PRDX3 OTLB2WEU Strong Altered Expression [161]
PRSS16 OTVCZ5V1 Strong Biomarker [280]
PSMD7 OT7PZZ4K Strong Biomarker [111]
PSMG1 OTZ5I6UM Strong Biomarker [67]
RAB32 OTTR4H7S Strong Altered Expression [281]
RABEPK OTCZSREH Strong Biomarker [111]
RAG1 OTV131E4 Strong Biomarker [282]
RASD1 OT2BAJHK Strong Genetic Variation [283]
RBMS3 OTFSC9MR Strong Biomarker [105]
RGCC OTYJMLWM Strong Biomarker [284]
RMDN1 OTE1NB6U Strong Biomarker [177]
RMDN2 OTK5WSFI Strong Biomarker [177]
RMDN3 OTKO7AUM Strong Biomarker [177]
SEMA7A OT0ZJK64 Strong Biomarker [285]
SIGLEC1 OTNWSQA9 Strong Altered Expression [286]
SRRM2 OTSIMMC9 Strong Biomarker [105]
SUGP1 OT7W0EB8 Strong Biomarker [105]
SYBU OT3FQV7N Strong Biomarker [177]
SYN1 OTMNPWC1 Strong Biomarker [287]
TAGAP OTHJNNO2 Strong Biomarker [288]
TBCA OTCCWMGK Strong Biomarker [289]
TOB1 OTNW949D Strong Biomarker [290]
TSC22D3 OT03UM03 Strong Biomarker [291]
TSPAN32 OTSXW7EW Strong Altered Expression [292]
CLDN5 OTUX60YO Definitive Biomarker [293]
MSC OTBRPZL5 Definitive Biomarker [294]
MYDGF OT9HRPL6 Definitive Biomarker [32]
PLP1 OT8CM9CX Definitive Biomarker [295]
RPS19 OTBKGP48 Definitive Biomarker [296]
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⏷ Show the Full List of 185 DOT(s)

References

1 The ChEMBL database in 2017. Nucleic Acids Res. 2017 Jan 4;45(D1):D945-D954.
2 A Role for the Non-Receptor Tyrosine Kinase Abl2/Arg in Experimental Neuroinflammation.J Neuroimmune Pharmacol. 2018 Jun;13(2):265-276. doi: 10.1007/s11481-018-9783-8. Epub 2018 Mar 17.
3 Dexmedetomidine, an Alpha 2a Adrenergic Receptor Agonist, Mitigates Experimental Autoimmune Encephalomyelitis by Desensitization of CXCR7 in Microglia.Biochemistry. 2018 Jul 17;57(28):4197-4205. doi: 10.1021/acs.biochem.8b00430. Epub 2018 Jun 26.
4 Vascular adhesion protein-1 is actively involved in the development of inflammatory lesions in rat models of multiple sclerosis.J Neuroinflammation. 2018 May 1;15(1):128. doi: 10.1186/s12974-018-1152-2.
5 Activating 7 nicotinic acetylcholine receptor inhibits NLRP3 inflammasome through regulation of -arrestin-1.CNS Neurosci Ther. 2017 Nov;23(11):875-884. doi: 10.1111/cns.12758. Epub 2017 Sep 21.
6 Deficiency of -Arrestin 2 in Dendritic Cells Contributes to Autoimmune Diseases.J Immunol. 2019 Jan 15;202(2):407-420. doi: 10.4049/jimmunol.1800261. Epub 2018 Dec 12.
7 The Alzheimer's Disease-Associated Protein BACE1 Modulates T Cell Activation and Th17 Function.J Immunol. 2019 Aug 1;203(3):665-675. doi: 10.4049/jimmunol.1800363. Epub 2019 Jun 17.
8 Deletion of the complement anaphylatoxin C3a receptor attenuates, whereas ectopic expression of C3a in the brain exacerbates, experimental autoimmune encephalomyelitis.J Immunol. 2004 Oct 1;173(7):4708-14. doi: 10.4049/jimmunol.173.7.4708.
9 RON-regulated innate immunity is protective in an animal model of multiple sclerosis.Ann Neurol. 2005 Jun;57(6):883-95. doi: 10.1002/ana.20502.
10 Variants within the immunoregulatory CBLB gene are associated with multiple sclerosis.Nat Genet. 2010 Jun;42(6):495-7. doi: 10.1038/ng.584. Epub 2010 May 9.
11 Cellular FLIP (long isoform) overexpression in T cells drives Th2 effector responses and promotes immunoregulation in experimental autoimmune encephalomyelitis.J Immunol. 2004 Dec 1;173(11):6619-26. doi: 10.4049/jimmunol.173.11.6619.
12 The change of PD1, PDL1 in experimental autoimmune encephalomyelitis treated by 1,25(OH)(2)D(3).J Neuroimmunol. 2020 Jan 15;338:577079. doi: 10.1016/j.jneuroim.2019.577079. Epub 2019 Oct 31.
13 A CD40 targeting peptide prevents severe symptoms in experimental autoimmune encephalomyelitis.J Neuroimmunol. 2019 Jul 15;332:8-15. doi: 10.1016/j.jneuroim.2019.03.013. Epub 2019 Mar 21.
14 Endogenous Expression of the Human CD83 Attenuates EAE Symptoms in Humanized Transgenic Mice and Increases the Activity of Regulatory T Cells.Front Immunol. 2019 Jun 25;10:1442. doi: 10.3389/fimmu.2019.01442. eCollection 2019.
15 Inhibition of Cdk8/Cdk19 Activity Promotes Treg Cell Differentiation and Suppresses Autoimmune Diseases.Front Immunol. 2019 Aug 20;10:1988. doi: 10.3389/fimmu.2019.01988. eCollection 2019.
16 Acetylcholine-producing NK cells attenuate CNS inflammation via modulation of infiltrating monocytes/macrophages.Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6202-E6211. doi: 10.1073/pnas.1705491114. Epub 2017 Jul 10.
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