General Information of Disease (ID: DISW0LMR)

Disease Name Endometrial cancer
Synonyms
tumour of endometrium; neoplasm of endometrium; endometrial neoplasm; tumor of endometrium; malignant neoplasm of endometrium; endometrial Ca; primary malignant neoplasm of endometrium; malignant endometrial neoplasm; malignant endometrium neoplasm; endometrial cancer; cancer of endometrium; endometrial carcinoma, somatic; endometrial cancer, susceptibility to, autosomal dominant, somatic mutation; endometrium cancer; endometrial cancer, familial, autosomal dominant, somatic mutation
Disease Class 2C76: Endometrial cancer
Definition Primary or metastatic malignant neoplasm involving the endometrium (mucous membrane that lines the endometrial cavity).
Disease Hierarchy
DIS6OS2L: Endometrium neoplasm
DISAT1Z9: Advanced cancer
DIS3QDT8: Malignant uterine tumour
DISW0LMR: Endometrial cancer
ICD Code
ICD-11
ICD-11: 2C76
ICD-9
ICD-9: 182
Expand ICD-11
'2C76.Z
Expand ICD-9
182
Disease Identifiers
MONDO ID
MONDO_0011962
UMLS CUI
C0007103
MedGen ID
2840
SNOMED CT ID
188192002

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 3 Approved Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
Dostarlimab DM78NWP Approved Antibody [1]
Lurbinectedin DMEFRTZ Approved Small molecular drug [2]
Mirvetuximab soravtansine DM5S4LX Approved NA [2]
------------------------------------------------------------------------------------
This Disease is Treated as An Indication in 13 Clinical Trial Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
AL3818 DM3WP0N Phase 3 NA [2]
TKI258 DMYLT67 Phase 3 Small molecular drug [3]
DKN-01 DMOHT5V Phase 2 Antibody [2]
Folate binding protein vaccine DMW2SNN Phase 2 NA [4]
FP-1039 DMUAXS5 Phase 2 NA [5]
ONC201 DMM5SCF Phase 2 NA [2]
PF-04691502 DMS610L Phase 2 Small molecular drug [6]
Virexxa DMEXMV5 Phase 2 NA [7]
XBIO-101 DMUI7WV Phase 2 NA [2]
Folate binding protein-E39 DMA28O6 Phase 1/2 NA [8]
GALE-301 DMNEM46 Phase 1/2 NA [9]
Anti-meso-CAR vector transduced T cells DM5UQA9 Phase 1 CAR T Cell Therapy [10]
COTI-2 DM6K3JQ Phase 1 NA [2]
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 Drug(s)
This Disease is Treated as An Indication in 2 Discontinued Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
GSK1059615 DMI6KQM Discontinued in Phase 1 Small molecular drug [11]
RU-46556 DM8B1DH Terminated NA [12]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 177 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ADH7 TT3LE7P Limited Altered Expression [13]
ADIPOQ TTXKA7D Limited Genetic Variation [14]
AGR2 TT9K86S Limited Biomarker [15]
AGTR1 TT8DBY3 Limited Biomarker [16]
AKR1C3 TT5ZWB6 Limited Altered Expression [17]
AR TTKPW01 Limited Biomarker [18]
BRD2 TTDP48B Limited Biomarker [19]
CD44 TTWFBT7 Limited Altered Expression [20]
CHEK2 TT9ABMF Limited Genetic Variation [21]
DHCR24 TTTK0NH Limited Biomarker [22]
DICER1 TTTEOPU Limited Genetic Variation [23]
DNMT3B TT6VZ78 Limited Altered Expression [24]
EIF4EBP1 TTKGEBL Limited Biomarker [25]
ESRRG TT9ZRHB Limited Biomarker [26]
EZR TTE47YC Limited Altered Expression [27]
GPI TT19JIZ Limited Altered Expression [28]
HDGF TTKGV26 Limited Altered Expression [29]
HNF1A TT01M3K Limited Biomarker [30]
HSD17B2 TT0PT1R Limited Biomarker [31]
HTRA1 TT8POQR Limited Biomarker [32]
IFNB1 TT4TZ8J Limited Biomarker [33]
IGFBP7 TTUQ01B Limited Biomarker [34]
JAK1 TT6DM01 Limited Altered Expression [35]
KCNN4 TT7M9I6 Limited Altered Expression [36]
KITLG TTDJ51N Limited Biomarker [37]
KLK4 TT4319X Limited Altered Expression [38]
LPAR1 TTQ6S1K Limited Biomarker [39]
LPAR2 TTB7Y8I Limited Altered Expression [40]
MDM2 TT9TE0O Limited Biomarker [41]
MGMT TTJ8DV7 Limited Genetic Variation [21]
MMP11 TTZW4MV Limited Biomarker [42]
MTDH TTH6SA5 Limited Biomarker [43]
MUC16 TTC1PS3 Limited Biomarker [44]
MUTYH TTNB0ZK Limited Genetic Variation [45]
OGG1 TTRU01G Limited Genetic Variation [46]
PAK4 TT7Y3BZ Limited Biomarker [47]
PPME1 TTXQ54R Limited Biomarker [48]
PSMD10 TT2H4LN Limited Biomarker [49]
PTGES2 TTWU04I Limited Biomarker [50]
S100A6 TT716MY Limited Biomarker [51]
SCGB1A1 TTONPVW Limited Altered Expression [52]
SLC22A16 TTITAVR Limited Biomarker [53]
SNCG TT5TQNZ Limited Altered Expression [54]
XPA TTGT87E Limited Genetic Variation [55]
ALCAM TT2AFT6 Disputed Biomarker [56]
EGLN1 TT9ISBX Disputed Biomarker [57]
FLT4 TTDCBX5 Disputed Biomarker [58]
FOLR1 TTVC37M Disputed Genetic Variation [59]
HGFAC TTD96RW Disputed Altered Expression [60]
NEDD4 TT1QU6G Disputed Altered Expression [61]
SLC7A5 TTPH2JB Disputed Altered Expression [62]
SRD5A2 TTT02K8 Disputed Altered Expression [63]
ST14 TTPRO7W Disputed Altered Expression [60]
VEGFD TTOM5H4 Disputed Altered Expression [58]
CDK8 TTBJR4L moderate Altered Expression [64]
CYP11A1 TTSYVO6 moderate Altered Expression [63]
FBXW7 TT29KY7 moderate Biomarker [65]
FGR TTPOGS1 moderate Biomarker [66]
FOLR2 TTT54CI moderate Biomarker [67]
PDE7A TT1BC3A moderate Biomarker [68]
ADAMTS1 TTS2TEI Strong Altered Expression [69]
AGPAT2 TT9AYVR Strong Biomarker [70]
AMHR2 TTZDCPK Strong Altered Expression [71]
ARRB1 TTMVD4A Strong Biomarker [72]
ARRB2 TT8SO2I Strong Biomarker [73]
ATAD2 TT9A0HI Strong Altered Expression [74]
ATR TT8ZYBQ Strong Biomarker [75]
BRD3 TTHE657 Strong Biomarker [19]
BST2 TT90BJT Strong Biomarker [76]
BTG1 TTL7N2W Strong Altered Expression [77]
C1QBP TTWTD7F Strong Altered Expression [78]
CACNA2D3 TTN7T29 Strong Biomarker [79]
CASP5 TTWR48J Strong Genetic Variation [80]
CASP7 TTM7Y45 Strong Genetic Variation [81]
CCK TT90CMU Strong Biomarker [82]
CCNA2 TTAMQ62 Strong Biomarker [83]
CD274 TT8ZLTI Strong Biomarker [84]
CDC20 TTBKFDV Strong Biomarker [85]
CDC25A TTLZS4Q Strong Biomarker [86]
CDC25C TTESBNC Strong Biomarker [87]
CGB3 TTUH273 Strong Altered Expression [88]
CHST15 TTFK7E1 Strong Genetic Variation [89]
COMT TTKWFB8 Strong Genetic Variation [90]
CRHR2 TTIY658 Strong Biomarker [91]
CSPG4 TT7MYXI Strong Altered Expression [92]
CTCFL TTY0RZT Strong Biomarker [93]
CTNNB1 TTRPKQG Strong Genetic Variation [94]
CTSV TTSD9T1 Strong Biomarker [95]
CUL3 TTPCU0Q Strong Biomarker [19]
CXCL11 TTWG0RE Strong Biomarker [96]
CYP3A4 TTWP7HQ Strong Genetic Variation [97]
DDX5 TTZKPVC Strong Biomarker [29]
DEPTOR TTLYP6D Strong Biomarker [98]
DGKA TTGL8F0 Strong Biomarker [99]
EGFL7 TT7WD0H Strong Biomarker [100]
EIF2AK2 TTXEZJ4 Strong Altered Expression [101]
EPCAM TTZ8WH4 Strong Biomarker [102]
ESRRA TTPNQAC Strong Biomarker [103]
ESRRB TTKF0XS Strong Biomarker [104]
F2RL2 TTVSEBF Strong Altered Expression [105]
F2RL3 TTD0652 Strong Biomarker [106]
FAM83B TT1Q347 Strong Biomarker [107]
FECH TTQ6VF4 Strong Biomarker [108]
FGF4 TTCEKVZ Strong Altered Expression [109]
FOXO1 TTLRVIA Strong Biomarker [30]
FTO TTFW3BT Strong Biomarker [110]
GALR1 TTX3HNZ Strong Genetic Variation [111]
GHRHR TTG4R8V Strong Biomarker [112]
GNRH1 TT0ID4A Strong Genetic Variation [113]
GNRHR TT8R70G Strong Altered Expression [114]
HAAO TTWON83 Strong Posttranslational Modification [115]
HOXB13 TTZ6I58 Strong Altered Expression [116]
HPN TT25MVL Strong Biomarker [117]
HSD17B13 TTDJYZR Strong Altered Expression [118]
HSD17B4 TTL1WGS Strong Genetic Variation [119]
HSPA5 TTW26OG Strong Biomarker [120]
HTR1B TTK8CXU Strong Biomarker [121]
IGFBP6 TTLAYV8 Strong Altered Expression [122]
IL11RA TTZPLJS Strong Biomarker [123]
KDM4A TTZHPB8 Strong Biomarker [124]
KLK5 TTULSEW Strong Biomarker [125]
KRT17 TTKV0EC Strong Biomarker [126]
LILRB2 TTHC6XU Strong Biomarker [127]
MAP3K1 TTW8TJI Strong Genetic Variation [128]
MSLN TT4RXME Strong Biomarker [102]
MSMB TTYH1ZK Strong Biomarker [129]
MSTN TTM8I2X Strong Altered Expression [130]
MTNR1B TT32JK8 Strong Biomarker [131]
NPY5R TTY6EWA Strong Altered Expression [132]
NR1H3 TTECBXN Strong Biomarker [133]
NRP2 TTRXUVC Strong Altered Expression [134]
NTSR1 TTTUMEP Strong Altered Expression [135]
OLFM4 TTK1CX7 Strong Altered Expression [136]
P2RY2 TTOZHQC Strong Altered Expression [137]
PCSK6 TT75LN9 Strong Altered Expression [138]
PDGFD TTSN0GA Strong Altered Expression [139]
PGC TT7K6AD Strong Altered Expression [140]
PIM2 TT69J2Z Strong Biomarker [141]
PKN1 TTSL41O Strong Biomarker [142]
PLOD2 TT8MEUD Strong Biomarker [143]
PMS1 TTX1ISF Strong Genetic Variation [144]
PRLR TTBPXMA Strong Biomarker [145]
PRMT1 TTVOJAI Strong Biomarker [146]
PROM1 TTXMZ81 Strong Altered Expression [20]
PTPN7 TT2C1DT Strong Biomarker [147]
RICTOR TT143WL Strong Altered Expression [148]
ROR1 TTDEJAU Strong Biomarker [149]
ROR2 TTUDPCI Strong Biomarker [149]
RXFP1 TTMAHD1 Strong Biomarker [150]
SCUBE2 TTWREQP Strong Biomarker [151]
SERPINA6 TTJL8VG Strong Altered Expression [152]
SGO1 TTBPKGD Strong Biomarker [153]
SGPL1 TT618Q2 Strong Biomarker [154]
SIRPA TTBRJS9 Strong Biomarker [155]
SIRT5 TTH0IOD Strong Altered Expression [156]
SLC9A1 TTGSEFH Strong Altered Expression [157]
SREBF1 TTER0UB Strong Biomarker [30]
SSRP1 TTETDKQ Strong Biomarker [158]
STC2 TT4EFTR Strong Biomarker [159]
STEAP1 TT9E64S Strong Altered Expression [160]
TMPRSS6 TTL9KE7 Strong Biomarker [131]
TNFRSF11A TT3K9S2 Strong Biomarker [161]
TNFSF12 TTBTDM1 Strong Altered Expression [162]
TNK2 TTIET93 Strong Genetic Variation [163]
TNKS2 TTFQI4H Strong Genetic Variation [164]
TOP2B TT4NVEM Strong Genetic Variation [165]
TRIM27 TTTO3QN Strong Altered Expression [166]
TWIST1 TTX1MY7 Strong Altered Expression [167]
UTS2R TTW5UDX Strong Genetic Variation [168]
VSIR TT51SK8 Strong Altered Expression [169]
ABCC4 TTUEAFL Definitive Biomarker [170]
CSF1 TT0IQER Definitive Biomarker [35]
GLO1 TTV9A7R Definitive Altered Expression [171]
KRT19 TT3JF9E Definitive Altered Expression [172]
MTA1 TTO4HUS Definitive Altered Expression [25]
PTP4A3 TT7YM8D Definitive Biomarker [173]
VEGFB TTPJQHE Definitive Biomarker [144]
------------------------------------------------------------------------------------
⏷ Show the Full List of 177 DTT(s)
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC14A2 DT8QC7K Strong Genetic Variation [168]
SLC2A6 DTS4MKQ Strong Altered Expression [174]
------------------------------------------------------------------------------------
This Disease Is Related to 12 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
AKR1B10 DEP6GT1 Limited Altered Expression [175]
AKR1C1 DE7P2FB Limited Biomarker [176]
HSD17B7 DEDMWFX Limited Altered Expression [118]
ACSS2 DEE76VW Disputed Biomarker [177]
HSD3B1 DERDQWN Disputed Altered Expression [63]
HSD3B2 DEN0GVQ Disputed Altered Expression [63]
BAAT DERA3OF Strong Altered Expression [178]
CHST3 DEQIZP2 Strong Biomarker [179]
GGCT DEKW6PB Strong Biomarker [180]
PER1 DE9HF0I Strong Altered Expression [181]
UGT2B17 DEAZDL8 Strong Altered Expression [182]
UGT2B7 DEB3CV1 Strong Genetic Variation [183]
------------------------------------------------------------------------------------
⏷ Show the Full List of 12 DME(s)
This Disease Is Related to 303 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ADIPOR1 OT65ZFZN Limited Biomarker [184]
AZIN2 OT8OB7CG Limited Biomarker [185]
BHLHE41 OTY9GJ1Y Limited Biomarker [186]
CD82 OTH8MC64 Limited Altered Expression [187]
CDKN2B OTAG24N1 Limited Biomarker [188]
CHD4 OTBDEHDP Limited Genetic Variation [189]
CHFR OTRAD2TT Limited Biomarker [190]
CIB1 OT4BVCRU Limited Biomarker [37]
CKS1B OTNUPLUJ Limited Biomarker [37]
CTBP2 OTGZGT87 Limited Biomarker [129]
CTCF OT8ZB70U Limited Genetic Variation [191]
CTHRC1 OTV88X2G Limited Biomarker [192]
EBAG9 OTTQLQCP Limited Altered Expression [193]
ERCC2 OT1C8HQ4 Limited Genetic Variation [194]
FGF3 OT9PK2SI Limited Genetic Variation [195]
FOXA2 OTJOCVOY Limited Biomarker [196]
GADL1 OTJM4A0R Limited Biomarker [185]
GHRH OT94U6MO Limited Biomarker [112]
HOXA10 OTB6GQ09 Limited Altered Expression [197]
HSD17B6 OTSB55D2 Limited Altered Expression [13]
HTRA2 OTC7616F Limited Biomarker [198]
INTS2 OT2N5TCK Limited Genetic Variation [195]
JAZF1 OTXTYSYD Limited Biomarker [129]
KLF9 OTBFEJRQ Limited Biomarker [199]
LEF1 OTWS5I5H Limited Altered Expression [200]
LSR OTR8Y32X Limited Biomarker [201]
MMP26 OT9O89KU Limited Altered Expression [202]
NEU1 OTH9BY8Y Limited Biomarker [100]
NEURL1 OT2C4P70 Limited Biomarker [100]
NUCB2 OTHO6JWN Limited Biomarker [203]
PDCD4 OTZ6NXUX Limited Altered Expression [204]
PPP2R1A OTYA3GB4 Limited Genetic Variation [205]
PROK1 OT8S7RUG Limited Biomarker [206]
PTPA OTRGFOI7 Limited Genetic Variation [205]
RASSF1 OTEZIPB7 Limited Posttranslational Modification [207]
RPL10 OTBHOZGC Limited Genetic Variation [208]
RPL11 OT3VZ6OE Limited Genetic Variation [208]
RPL36A OT1LYV85 Limited Biomarker [209]
SLN OTERIU75 Limited Biomarker [210]
SMAD2 OTC6VB4K Limited Biomarker [211]
SOCS2 OTBPNKJQ Limited Altered Expression [212]
SOX17 OT9H4WWE Limited Biomarker [213]
SUMO1 OTJFD4P5 Limited Altered Expression [214]
TET1 OTZDHT1D Limited Altered Expression [171]
TGFBR3 OTQOOUC4 Limited Genetic Variation [215]
THEMIS2 OTI1OBLN Limited Biomarker [216]
TTF1 OT4K90WD Limited Biomarker [217]
ACCS OTHIHI9D Disputed Biomarker [177]
CCN3 OTOW5YL4 Disputed Biomarker [218]
ELAVL2 OT6EJ8MQ Disputed Biomarker [219]
HAND2 OTCXYW4Y Disputed Biomarker [220]
LPXN OTUNV3CK Disputed Altered Expression [221]
PLA2G15 OT6VJTPA Disputed Biomarker [177]
PRDX3 OTLB2WEU Disputed Biomarker [222]
SEMA3F OTQFMS8S Disputed Altered Expression [223]
SIRT7 OT5M4OT4 Disputed Biomarker [224]
SIX1 OT70YYWM Disputed Altered Expression [225]
COX7A2L OTY21FKV moderate Biomarker [226]
DCC OT2C1SHW moderate Altered Expression [227]
EMP2 OTPS2H0L moderate Biomarker [228]
FOXA1 OTEBY0TD moderate Biomarker [229]
PIK3R2 OTZSUQK5 moderate Biomarker [230]
RAP1GAP OTC31ONQ moderate Biomarker [231]
SCGB2A1 OT9L87U9 moderate Biomarker [232]
SRA1 OTYOGMTG moderate Biomarker [233]
STK11 OT1YZSP3 moderate Biomarker [234]
ABCF2 OTXIBZ3N Strong Altered Expression [235]
ABHD5 OTY829Z3 Strong Biomarker [236]
ADARB1 OTGKSZEV Strong Posttranslational Modification [237]
ADD2 OTRCPCD2 Strong Biomarker [238]
ADGRG2 OTPAD5S1 Strong Biomarker [239]
ADSL OTSNJALL Strong Biomarker [240]
AFDN OTTRU341 Strong Altered Expression [241]
AMELX OTIN26MM Strong Altered Expression [242]
AMH OT5FH4BD Strong Biomarker [243]
ANO2 OT650E98 Strong Biomarker [244]
AQP2 OTQLBKK6 Strong Altered Expression [245]
ARHGEF1 OTXU4HBW Strong Biomarker [246]
ASCL2 OT3D62WB Strong Biomarker [121]
ATAD1 OTJ02XFL Strong Genetic Variation [247]
ATP6AP2 OT0IABVV Strong Altered Expression [248]
BBS2 OTPF9JIB Strong Altered Expression [249]
BCOR OTG013AX Strong Genetic Variation [250]
BHLHE22 OTZUQY5L Strong Biomarker [220]
BHLHE40 OTITX14U Strong Biomarker [186]
BLM OTEJOAJX Strong Genetic Variation [251]
C1GALT1C1 OTRTZUF5 Strong Genetic Variation [252]
CALB1 OTM7IXDG Strong Altered Expression [253]
CAPG OTJ86KI6 Strong Biomarker [254]
CAVIN3 OTOLBK79 Strong Genetic Variation [255]
CCDC7 OTNCL9JR Strong Biomarker [256]
CDC42SE2 OT8SG9I1 Strong Biomarker [257]
CDC73 OT6JASZ1 Strong Biomarker [258]
CDO1 OTLG1P77 Strong Posttranslational Modification [220]
CELF4 OT4FS4F5 Strong Biomarker [259]
CGRRF1 OTLMNRCL Strong Altered Expression [260]
CHL1 OT6E6E8P Strong Biomarker [261]
CIRBP OTXWTPBL Strong Biomarker [262]
CLDN3 OT71MN9S Strong Biomarker [263]
CLDN7 OTNE0XHQ Strong Biomarker [264]
COL14A1 OTLNJ13O Strong Biomarker [265]
COPZ2 OTM5W0BK Strong Posttranslational Modification [266]
CPEB1 OTLCXC6H Strong Altered Expression [267]
CTNNBIP1 OTX9SBJG Strong Biomarker [268]
DAB1 OTPL9MA3 Strong Altered Expression [269]
DAB2 OTRMQTMZ Strong Biomarker [270]
DAB2IP OTF456VC Strong Genetic Variation [271]
DACH1 OTMKNAGG Strong Altered Expression [272]
DDT OTF5HTYL Strong Biomarker [273]
DDX39B OTEVCFVU Strong Biomarker [120]
DDX3X OTDO4TRX Strong Altered Expression [274]
DDX53 OTHK3EGZ Strong Biomarker [275]
DHRS11 OTU3J0ZL Strong Altered Expression [118]
DLGAP4 OTNELLIN Strong Genetic Variation [276]
DOLPP1 OTRHICBA Strong Biomarker [277]
DPH7 OTTD7ZZ8 Strong Genetic Variation [173]
DPYSL4 OT3SBS2S Strong Biomarker [265]
DROSHA OTCE68KZ Strong Altered Expression [278]
DUSP6 OT4H6RKW Strong Altered Expression [279]
DYNLL2 OTLIT58K Strong Genetic Variation [280]
E2F7 OTWW358N Strong Biomarker [281]
EDIL3 OTDVVNS0 Strong Altered Expression [282]
EIF3C OTR8RF9X Strong Altered Expression [283]
EIF3H OT61RBF5 Strong Altered Expression [283]
EIF4G1 OT2CF1E6 Strong Altered Expression [283]
EIF5 OT79PQUN Strong Biomarker [283]
EIF6 OTEXMUED Strong Biomarker [283]
EMP3 OTODMJ1D Strong Biomarker [244]
ENOSF1 OT65D3ZK Strong Genetic Variation [284]
ERMP1 OT9CIEO2 Strong Altered Expression [285]
ERRFI1 OT7VZ2IZ Strong Biomarker [209]
ETV5 OTE2OBM4 Strong Biomarker [286]
FAT4 OT7QONNV Strong Altered Expression [287]
FHDC1 OTMMV8ZN Strong Biomarker [100]
FLOT1 OT0JPPJZ Strong Altered Expression [288]
FOXD3 OTXYV6GO Strong Biomarker [289]
FZD6 OTBCPII8 Strong Altered Expression [20]
GAB2 OTBFN705 Strong Altered Expression [290]
GEMIN2 OT4L6TLL Strong Altered Expression [291]
GKN1 OT7ZYFQ9 Strong Biomarker [292]
GORASP2 OTL3PLD2 Strong Biomarker [293]
GPR68 OT1NXSMN Strong Altered Expression [294]
GREB1 OTU6ZA26 Strong Biomarker [295]
H4C1 OTB71W46 Strong Biomarker [296]
HERPUD1 OT9EROL6 Strong Biomarker [297]
HIVEP1 OT7CAG4A Strong Biomarker [298]
HJURP OTWMV16B Strong Biomarker [299]
HNF1B OTSYIC3T Strong Genetic Variation [300]
HOMER2 OT4JGKJF Strong Altered Expression [301]
HOXB3 OT9UC5PE Strong Altered Expression [302]
HOXB9 OTMVHQOU Strong Biomarker [303]
HPR OTXSC9UB Strong Genetic Variation [304]
HS3ST2 OTWFA0GJ Strong Biomarker [305]
HYAL3 OTG6VUSP Strong Altered Expression [306]
IGSF9 OTNTKWS2 Strong Biomarker [307]
JPH4 OTRLNPJK Strong Altered Expression [308]
JPT1 OT6CRZEU Strong Biomarker [309]
KCNE1 OTZNQUW9 Strong Biomarker [310]
KDM4B OT5P1UPY Strong Altered Expression [124]
KIF5B OTT34MT8 Strong Altered Expression [311]
KLF12 OTVH4KD4 Strong Altered Expression [312]
KLLN OTV3FPH0 Strong Genetic Variation [313]
KLRC3 OT9EPHV3 Strong Biomarker [240]
KMT2C OTC59BCO Strong Genetic Variation [250]
KNSTRN OTYA7UXS Strong Biomarker [219]
LAT OTZC1XZ1 Strong Biomarker [314]
LEFTY2 OT3RX4QF Strong Altered Expression [315]
LGALS7 OTMSVI7R Strong Altered Expression [316]
LLGL1 OTAIQSXZ Strong Altered Expression [317]
LRG1 OTLD0KWA Strong Altered Expression [318]
LYPD5 OTGP7UKA Strong Biomarker [25]
MACROD1 OTWFEVRW Strong Altered Expression [319]
MAGI2 OTXDDKZS Strong Biomarker [320]
MAL OTBM30SW Strong Posttranslational Modification [321]
MAML3 OTZFV53Z Strong Altered Expression [322]
MAP2K4 OTZPZX11 Strong Altered Expression [323]
MARCHF3 OT89V4N5 Strong Altered Expression [324]
MARCHF7 OTG9SF10 Strong Altered Expression [325]
MARCHF8 OTH7PNN2 Strong Genetic Variation [326]
MAX OTKZ0YKM Strong Biomarker [327]
MBD4 OTWR9YXE Strong Genetic Variation [80]
MDC1 OTEUQH4J Strong Biomarker [328]
MDH2 OT7364GY Strong Altered Expression [329]
METTL14 OT6TPQMH Strong Genetic Variation [330]
MINDY4 OTBZ2SZB Strong Biomarker [331]
MLH3 OT91PPBI Strong Genetic Variation [332]
MRE11 OTGU8TZM Strong Genetic Variation [328]
MRPS18B OT1K9PFX Strong Altered Expression [333]
MSN OTZJ4J6G Strong Biomarker [334]
MT1E OTXJKU4Y Strong Altered Expression [335]
MYBL2 OTZ3JX8Q Strong Altered Expression [336]
MZF1 OTMVZCPW Strong Altered Expression [337]
NCOA1 OTLIUJQD Strong Biomarker [338]
NCOA2 OTMQFPBB Strong Biomarker [339]
NEDD4L OT1B19RU Strong Altered Expression [340]
NELL2 OTS4MJZ7 Strong Altered Expression [134]
NFYA OTWFFOVH Strong Biomarker [341]
NID1 OTKLBLS6 Strong Biomarker [286]
NLRP7 OTE9BI32 Strong Biomarker [342]
NOL3 OT1K0L0D Strong Biomarker [343]
NR2F1 OTGWZWYL Strong Biomarker [344]
NRIP1 OTIZOJQV Strong Biomarker [345]
NSD2 OTQ6SW4R Strong Biomarker [346]
NTMT1 OTLRH78U Strong Genetic Variation [347]
NUP98 OTNT12G2 Strong Posttranslational Modification [237]
NUPR1 OT4FU8C0 Strong Biomarker [286]
OTUB1 OT8WWM9O Strong Altered Expression [348]
PAEP OTQA0NV4 Strong Altered Expression [349]
PAQR5 OTGGWXQE Strong Altered Expression [350]
PAQR7 OTIWX5AM Strong Altered Expression [350]
PAQR8 OTGZ8W9F Strong Altered Expression [350]
PARD3 OTH5BPLO Strong Altered Expression [105]
PAX2 OTKP1N8F Strong Biomarker [351]
PDIA3 OTHPQ0Q3 Strong Altered Expression [352]
PELP1 OTVXQNOT Strong Biomarker [353]
PIK3R1 OT5BZ1J9 Strong Genetic Variation [354]
PIWIL1 OT7CRGZ3 Strong Biomarker [355]
PIWIL2 OT1PXQIF Strong Biomarker [356]
PLXNA1 OTN0BING Strong Altered Expression [357]
PMS2 OTNLWTMI Strong Genetic Variation [358]
PNN OT0HXICH Strong Biomarker [359]
POLD1 OTWO4UCJ Strong Genetic Variation [360]
POLE OTFM3MMU Strong Genetic Variation [361]
POT1 OTNBXJCQ Strong Biomarker [362]
POU4F3 OTILD0XS Strong Biomarker [320]
PRAP1 OT48QD82 Strong Genetic Variation [363]
PRB2 OTAD4JZ0 Strong Altered Expression [364]
PRG2 OT0BCPQG Strong Biomarker [298]
PSMD4 OTH1VZTM Strong Altered Expression [365]
PSME3 OTSTC4YY Strong Genetic Variation [366]
PTPN18 OT0S09B3 Strong Biomarker [367]
PTPRD OTZPJ3GX Strong Biomarker [368]
PTPRN OTAP7NOL Strong Biomarker [369]
RAD50 OTYMU9G1 Strong Genetic Variation [328]
RBL2 OTBQSOE6 Strong Altered Expression [370]
RBMX OTFZN66E Strong Biomarker [198]
RIT1 OTVNOGOH Strong Altered Expression [371]
RNASE1 OTKZ7CO9 Strong Genetic Variation [372]
RNF144B OTN7FCDE Strong Biomarker [373]
RPL17 OTTYMPS6 Strong Biomarker [374]
RPL22 OTVCN8K0 Strong Genetic Variation [375]
SCAF11 OTX59D0X Strong Altered Expression [291]
SEMA3B OTCZCPMS Strong Altered Expression [376]
SEMA5A OTUOIOJV Strong Altered Expression [377]
SESN1 OTSFDZWL Strong Biomarker [378]
SFN OTLJCZ1U Strong Altered Expression [379]
SHBG OTPWU5IW Strong Genetic Variation [380]
SIRT4 OT5S0J23 Strong Altered Expression [156]
SLIT3 OTU8MKEU Strong Biomarker [381]
SMOC2 OTK1EQ49 Strong Altered Expression [20]
SMUG1 OT2YIOCQ Strong Biomarker [382]
SOX18 OTPUMHWA Strong Biomarker [383]
SOX3 OT1CRCOB Strong Biomarker [384]
SOX4 OTSS40SS Strong Altered Expression [383]
SOX6 OTT0W0LE Strong Biomarker [385]
SOX7 OTOZOFAG Strong Altered Expression [200]
SPAM1 OTMPOB4E Strong Altered Expression [306]
SPATA2 OTOA45GL Strong Biomarker [374]
SPINT1 OT1CLR5L Strong Biomarker [291]
SPOCK2 OTXSVTSA Strong Biomarker [386]
SPON1 OTC06MY4 Strong Biomarker [387]
SPOP OTP0107S Strong Biomarker [388]
SPP2 OTX254AR Strong Genetic Variation [389]
ST6GALNAC1 OT3JQD99 Strong Genetic Variation [252]
STARD13 OTB4U1HY Strong Genetic Variation [280]
STIP1 OT7TXLOX Strong Genetic Variation [390]
SUFU OT0IRYG1 Strong Altered Expression [391]
SUSD2 OTSJTAZP Strong Altered Expression [392]
TBX5 OT70PISV Strong Biomarker [220]
TEAD1 OTK6971C Strong Altered Expression [201]
TES OTL8PP6V Strong Posttranslational Modification [393]
TET3 OT76U3YF Strong Biomarker [394]
TFAP2B OTR1T8E9 Strong Altered Expression [395]
TFAP2C OTUDIW05 Strong Altered Expression [396]
THBS2 OTXET551 Strong Altered Expression [397]
THUMPD1 OTKU8KWH Strong Biomarker [398]
TMEFF2 OT1WZ2QO Strong Posttranslational Modification [265]
TNFAIP8 OT1G9297 Strong Genetic Variation [399]
TNXB OTVBWAV5 Strong Biomarker [400]
TOPBP1 OT6UPZPD Strong Genetic Variation [165]
TRA2B OTZYQW52 Strong Biomarker [401]
TRAF4 OTJLRVMC Strong Altered Expression [402]
TRAM1 OT3I0H8E Strong Biomarker [403]
TRIM22 OTJBLG5R Strong Biomarker [404]
TRIM44 OT0B1T2B Strong Biomarker [405]
TSHZ1 OTYQ9ECW Strong Genetic Variation [406]
TSPYL5 OT7QEI2X Strong Biomarker [407]
CCDC54 OTW5WCX9 Definitive Biomarker [408]
CCL18 OT7JYSK9 Definitive Altered Expression [311]
EFEMP2 OT0I2B4J Definitive Biomarker [298]
ELF3 OTUTLEQO Definitive Biomarker [409]
HMMR OT4M0JTZ Definitive Altered Expression [410]
HTRA3 OTXJ0H4X Definitive Biomarker [411]
MAPK8IP2 OTDUHLN0 Definitive Biomarker [369]
MSH6 OT46FP09 Definitive Autosomal dominant [412]
MUC20 OTYYE1GK Definitive Biomarker [413]
NOP53 OTA2YKO6 Definitive Altered Expression [414]
PGK1 OT6V1ICH Definitive Altered Expression [415]
RBM10 OTES2MES Definitive Altered Expression [416]
RBP1 OTRP1MFC Definitive Biomarker [417]
RETN OTW5Z1NH Definitive Genetic Variation [418]
SPA17 OT8J7T7U Definitive Biomarker [408]
TRIB3 OTG5OS7X Definitive Altered Expression [310]
------------------------------------------------------------------------------------
⏷ Show the Full List of 303 DOT(s)

References

1 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health Human Services.
2 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
3 Phase 2 study of dovitinib in patients with metastatic or unresectable adenoid cystic carcinoma. Cancer. 2015 Aug 1;121(15):2612-7.
4 Clinical pipeline report, company report or official report of Galena Biopharma.
5 ClinicalTrials.gov (NCT01244438) Study of FP-1039 in Subjects With Endometrial Cancers. U.S. National Institutes of Health.
6 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7936).
7 ClinicalTrials.gov (NCT02064725) Virexxa (Sodium Cridanimod) w/Progestin Therapy in Pts w/Progesterone Receptor Neg Recurrent/Persistent Endometrial CA. U.S. National Institutes of Health.
8 Clinical pipeline report, company report or official report of Galena biopharma.
9 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800035004)
10 ClinicalTrials.gov (NCT02580747) Treatment of Relapsed and/or Chemotherapy Refractory Advanced Malignancies by CART-meso
11 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028447)
12 Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003252)
13 Expression of a retinol dehydrogenase (hRoDH-4), a member of the retinol/steroid dehydrogenase family implicated in retinoic acid biosynthesis, in normal and neoplastic endometria.Am J Obstet Gynecol. 2002 Apr;186(4):675-83. doi: 10.1067/mob.2002.122127.
14 Circulating adipokines and risk of obesity related cancers: A systematic review and meta-analysis.Obes Res Clin Pract. 2019 Jul-Aug;13(4):329-339. doi: 10.1016/j.orcp.2019.03.006. Epub 2019 Apr 16.
15 High AGR2 protein is a feature of low grade endometrial cancer cells.Oncotarget. 2018 Jul 31;9(59):31459-31472. doi: 10.18632/oncotarget.25838. eCollection 2018 Jul 31.
16 Silencing of angiotensin receptor 1 interferes with angiotensin II oncogenic activity in endometrial cancer.J Cell Biochem. 2018 Nov;119(11):9110-9121. doi: 10.1002/jcb.27174. Epub 2018 Aug 13.
17 AKR1C1 and AKR1C3 may determine progesterone and estrogen ratios in endometrial cancer.Mol Cell Endocrinol. 2006 Mar 27;248(1-2):126-35. doi: 10.1016/j.mce.2005.10.009. Epub 2005 Dec 9.
18 Delayed endometrial decidualisation in polycystic ovary syndrome; the role of AR-MAGEA11.J Mol Med (Berl). 2019 Sep;97(9):1315-1327. doi: 10.1007/s00109-019-01809-6. Epub 2019 Jun 29.
19 Opposing effects of cancer-type-specific SPOP mutants on BET protein degradation and sensitivity to BET inhibitors.Nat Med. 2017 Sep;23(9):1046-1054. doi: 10.1038/nm.4372. Epub 2017 Aug 14.
20 Targeting cancer stem cell signature gene SMOC-2 Overcomes chemoresistance and inhibits cell proliferation of endometrial carcinoma.EBioMedicine. 2019 Feb;40:276-289. doi: 10.1016/j.ebiom.2018.12.044. Epub 2018 Dec 26.
21 CHEK2, MGMT, SULT1E1 and SULT1A1 polymorphisms and endometrial cancer risk.Twin Res Hum Genet. 2011 Aug;14(4):328-32. doi: 10.1375/twin.14.4.328.
22 Preoperative quantitative dynamic contrast-enhanced MRI and diffusion-weighted imaging predict aggressive disease in endometrial cancer.Acta Radiol. 2018 Aug;59(8):1010-1017. doi: 10.1177/0284185117740932. Epub 2017 Nov 14.
23 Genetic variants in the microRNA machinery gene (Dicer) have a prognostic value in the management of endometrial cancer.J Cancer Res Ther. 2018 Oct-Dec;14(6):1279-1284. doi: 10.4103/0973-1482.187291.
24 RG108 induces the apoptosis of endometrial cancer Ishikawa cell lines by inhibiting the expression of DNMT3B and demethylation of HMLH1.Eur Rev Med Pharmacol Sci. 2017 Nov;21(22):5056-5064. doi: 10.26355/eurrev_201711_13818.
25 Metastasis-associated protein 1, modulated by miR-30c, promotes endometrial cancer progression through AKT/mTOR/4E-BP1 pathway.Gynecol Oncol. 2019 Jul;154(1):207-217. doi: 10.1016/j.ygyno.2019.04.005. Epub 2019 Apr 9.
26 The effect of estrogen on the proliferation of endometrial cancer cells is mediated by ERR through AKT and ERK1/2.Eur J Cancer Prev. 2014 Sep;23(5):418-24. doi: 10.1097/CEJ.0000000000000052.
27 Upregulation of miR-183-5p is responsible for the promotion of apoptosis and inhibition of the epithelial-mesenchymal transition, proliferation, invasion and migration of human endometrial cancer cells by downregulating Ezrin.Int J Mol Med. 2018 Nov;42(5):2469-2480. doi: 10.3892/ijmm.2018.3853. Epub 2018 Sep 4.
28 Autocrine motility factor promotes endometrial cancer progression by targeting GPER-1.Cell Commun Signal. 2019 Mar 5;17(1):22. doi: 10.1186/s12964-019-0336-4.
29 Hepatoma-Derived Growth Factor and DDX5 Promote Carcinogenesis and Progression of Endometrial Cancer by Activating -Catenin.Front Oncol. 2019 Apr 11;9:211. doi: 10.3389/fonc.2019.00211. eCollection 2019.
30 Roles of SIRT1/FoxO1/SREBP-1 in the development of progestin resistance in endometrial cancer.Arch Gynecol Obstet. 2018 Nov;298(5):961-969. doi: 10.1007/s00404-018-4893-3. Epub 2018 Sep 11.
31 Local estrogen metabolism (intracrinology) in endometrial cancer: A systematic review.Mol Cell Endocrinol. 2019 Jun 1;489:45-65. doi: 10.1016/j.mce.2018.10.004. Epub 2018 Oct 13.
32 Expression and functional significance of HtrA1 loss in endometrial cancer.Clin Cancer Res. 2011 Feb 1;17(3):427-36. doi: 10.1158/1078-0432.CCR-09-3069. Epub 2010 Nov 23.
33 Safety Studies in Tumor and Non-Tumor-Bearing Mice in Support of Clinical Trials Using Oncolytic VSV-IFN-NIS.Hum Gene Ther Clin Dev. 2016 Sep;27(3):111-22. doi: 10.1089/humc.2016.061.
34 IGFBP-rP1 acts as a potential tumor suppressor via the suppression of ERK signaling pathway in endometrial cancer cells.Mol Med Rep. 2017 Aug;16(2):1445-1450. doi: 10.3892/mmr.2017.6713. Epub 2017 Jun 7.
35 Colonystimulating factor 1 receptor inhibition blocks macrophage infiltration and endometrial cancer cell proliferation.Mol Med Rep. 2019 Apr;19(4):3139-3147. doi: 10.3892/mmr.2019.9963. Epub 2019 Feb 18.
36 Blockage of intermediate-conductance-Ca(2+) -activated K(+) channels inhibits progression of human endometrial cancer.Oncogene. 2007 Aug 2;26(35):5107-14. doi: 10.1038/sj.onc.1210308. Epub 2007 Feb 19.
37 TGF- activates APC through Cdh1 binding for Cks1 and Skp2 proteasomal destruction stabilizing p27kip1 for normal endometrial growth.Cell Cycle. 2016;15(7):931-47. doi: 10.1080/15384101.2016.1150393.
38 Kallikrein 4 overexpression in endometrial carcinoma and upregulation by estrogen via mitogen-activated protein kinase signal pathway.Int J Gynecol Cancer. 2009 Nov;19(8):1377-83. doi: 10.1111/IGC.0b013e3181a83e1a.
39 Altered expression of lysophosphatidic acid receptors, in association with the synthesis of estrogens and androgens in type 1 endometrial cancer biology.Gynecol Endocrinol. 2018 May;34(5):422-427. doi: 10.1080/09513590.2017.1409707. Epub 2017 Nov 28.
40 The G protein-coupled receptor GPR30 mediates the nontranscriptional effect of estrogen on the activation of PI3K/Akt pathway in endometrial cancer cells.Int J Gynecol Cancer. 2013 Jan;23(1):52-9. doi: 10.1097/IGC.0b013e31827912b8.
41 Impact of MDM2, TP53 and P14ARF Polymorphisms on Endometrial Cancer Risk and Onset.In Vivo. 2019 May-Jun;33(3):917-924. doi: 10.21873/invivo.11559.
42 Overexpression of the matrix metalloproteinase 11 gene is a potential biomarker for type 1 endometrial cancer.Oncol Lett. 2018 Jul;16(1):1073-1078. doi: 10.3892/ol.2018.8714. Epub 2018 May 16.
43 MTDH is an oncogene in multiple myeloma, which is suppressed by Bortezomib treatment.Oncotarget. 2016 Jan 26;7(4):4559-69. doi: 10.18632/oncotarget.6610.
44 Comparison of serum human epididymis protein 4 and CA125 on endometrial cancer detection: A meta-analysis.Clin Chim Acta. 2019 Jan;488:215-220. doi: 10.1016/j.cca.2018.11.011. Epub 2018 Nov 7.
45 Risk of extracolonic cancers for people with biallelic and monoallelic mutations in MUTYH.Int J Cancer. 2016 Oct 1;139(7):1557-63. doi: 10.1002/ijc.30197. Epub 2016 Jun 2.
46 Association analysis between 8-oxoguanine DNA glycosylase genetic variants and endometrial cancer susceptibility in Chinese Han population.J Pharm Pharmacol. 2015 Apr;67(4):559-64. doi: 10.1111/jphp.12348. Epub 2014 Dec 10.
47 Cross-talk between p21-activated kinase 4 and ER signaling triggers endometrial cancer cell proliferation.Oncotarget. 2017 Jul 12;8(40):68083-68094. doi: 10.18632/oncotarget.19188. eCollection 2017 Sep 15.
48 Inhibition of protein methylesterase 1 decreased cancerous phenotypes in endometrial adenocarcinoma cell lines and xenograft tumor models.Tumour Biol. 2016 Sep;37(9):11835-11842. doi: 10.1007/s13277-016-5036-8. Epub 2016 Apr 5.
49 Bu Shen Yang Xue Prescription Has Treating Effect on Endometrial Cancer through FSH/PI3K/AKT/Gankyrin/HIF-/cyclinD 1 Pathway in Ishikawa Cells.Evid Based Complement Alternat Med. 2018 Oct 9;2018:8412984. doi: 10.1155/2018/8412984. eCollection 2018.
50 Prostaglandin E2 triggers cytochrome P450 17 hydroxylase overexpression via signal transducer and activator of transcription 3 phosphorylation and promotes invasion in endometrial cancer.Oncol Lett. 2018 Oct;16(4):4577-4585. doi: 10.3892/ol.2018.9165. Epub 2018 Jul 18.
51 Isomorph expression of BAG-1 gene, ER and PR in endometrial cancer.Anticancer Res. 2010 Oct;30(10):4103-8.
52 Expression of uteroglobin and matrix metalloproteinase-9 genes in endometrial cancer: relationship to estrogen and progesterone receptor status.Oncol Rep. 2004 Feb;11(2):427-33.
53 Expression of organic cation transporter SLC22A16 in human endometria.Int J Gynecol Pathol. 2007 Jan;26(1):53-60. doi: 10.1097/01.pgp.0000225845.67245.b3.
54 Alternative splicing of synuclein gamma in endometrial cancer: identification of a novel isoform.Oncotarget. 2015 Sep 8;6(26):22553-63. doi: 10.18632/oncotarget.4155.
55 Nucleotide excision repair genotype and the incidence of endometrial cancer: effect of other risk factors on the association.Gynecol Oncol. 2006 Dec;103(3):891-6. doi: 10.1016/j.ygyno.2006.05.020. Epub 2006 Jun 23.
56 ALCAM shedding at the invasive front of the tumor is a marker of myometrial infiltration and promotes invasion in endometrioid endometrial cancer.Oncotarget. 2018 Mar 30;9(24):16648-16664. doi: 10.18632/oncotarget.24625. eCollection 2018 Mar 30.
57 Downregulation of Proline Hydroxylase 2 and Upregulation of Hypoxia-Inducible Factor 1 are Associated with Endometrial Cancer Aggressiveness.Cancer Manag Res. 2019 Nov 22;11:9907-9912. doi: 10.2147/CMAR.S223421. eCollection 2019.
58 Expression Profile of VEGF-C, VEGF-D, and VEGFR-3 in Different Grades of Endometrial Cancer.Curr Pharm Biotechnol. 2019;20(12):1004-1010. doi: 10.2174/1389201020666190718164431.
59 Final analysis of a phase I/IIa trial of the folate-binding protein-derived E39 peptide vaccine to prevent recurrence in ovarian and endometrial cancer patients.Cancer Med. 2019 Aug;8(10):4678-4687. doi: 10.1002/cam4.2378. Epub 2019 Jul 5.
60 Regulation of matriptase and HAI-1 system, a novel therapeutic target in human endometrial cancer cells.Oncotarget. 2018 Jan 3;9(16):12682-12694. doi: 10.18632/oncotarget.23913. eCollection 2018 Feb 27.
61 NEDD4 ubiquitin ligase is a putative oncogene in endometrial cancer that activates IGF-1R/PI3K/Akt signaling.Gynecol Oncol. 2015 Oct;139(1):127-33. doi: 10.1016/j.ygyno.2015.07.098. Epub 2015 Jul 17.
62 High throughput silencing identifies novel genes in endometrioid endometrial cancer.Taiwan J Obstet Gynecol. 2018 Apr;57(2):217-226. doi: 10.1016/j.tjog.2018.02.009.
63 Altered expression of genes involved in progesterone biosynthesis, metabolism and action in endometrial cancer.Chem Biol Interact. 2013 Feb 25;202(1-3):210-7. doi: 10.1016/j.cbi.2012.11.012. Epub 2012 Nov 27.
64 Tumor-suppressive effects of CDK8 in endometrial cancer cells.Cell Cycle. 2013 Mar 15;12(6):987-99. doi: 10.4161/cc.24003. Epub 2013 Mar 1.
65 Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition.Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25880-25890. doi: 10.1073/pnas.1911310116. Epub 2019 Nov 26.
66 Use of Porphysomes to detect primary tumour, lymph node metastases, intra-abdominal metastases and as a tool for image-guided lymphadenectomy: proof of concept in endometrial cancer.Theranostics. 2019 Apr 13;9(9):2727-2738. doi: 10.7150/thno.31225. eCollection 2019.
67 Folate receptor- targeted near-infrared fluorescence imaging in high-risk endometrial cancer patients: a tissue microarray and clinical feasibility study.Oncotarget. 2017 Dec 11;9(1):791-801. doi: 10.18632/oncotarget.23155. eCollection 2018 Jan 2.
68 The tumor-suppressive microRNA-1/133a cluster targets PDE7A and inhibits cancer cell migration and invasion in endometrial cancer.Int J Oncol. 2015 Jul;47(1):325-34. doi: 10.3892/ijo.2015.2986. Epub 2015 May 5.
69 PGF2-F-prostanoid receptor signalling via ADAMTS1 modulates epithelial cell invasion and endothelial cell function in endometrial cancer.BMC Cancer. 2010 Sep 14;10:488. doi: 10.1186/1471-2407-10-488.
70 Lysophosphatidic acid acyltransferase-beta is a prognostic marker and therapeutic target in gynecologic malignancies.Cancer Res. 2005 Oct 15;65(20):9415-25. doi: 10.1158/0008-5472.CAN-05-0516.
71 Transcriptome analysis reveals that Mllerian inhibiting substance regulates signaling pathways that contribute to endometrial carcinogenesis.Int J Oncol. 2015 May;46(5):2039-46. doi: 10.3892/ijo.2015.2920. Epub 2015 Mar 6.
72 Beta-arrestin 2 modulates resveratrol-induced apoptosis and regulation of Akt/GSK3? pathways. Biochim Biophys Acta. 2010 Sep;1800(9):912-8. doi: 10.1016/j.bbagen.2010.04.015. Epub 2010 May 7.
73 -arrestin-2 up-regulates toll-like receptor 2 signaling and inhibits apoptosis in human endometrial cancer heterotransplants in nude mice.BMC Cancer. 2019 Nov 1;19(1):1035. doi: 10.1186/s12885-019-6254-4.
74 ATAD2 overexpression links to enrichment of B-MYB-translational signatures and development of aggressive endometrial carcinoma.Oncotarget. 2015 Sep 29;6(29):28440-52. doi: 10.18632/oncotarget.4955.
75 Anti-Tumor Effect of Inhibition of DNA Damage Response Proteins, ATM and ATR, in Endometrial Cancer Cells.Cancers (Basel). 2019 Dec 1;11(12):1913. doi: 10.3390/cancers11121913.
76 Plasma membrane proteomics identifies bone marrow stromal antigen 2 as a potential therapeutic target in endometrial cancer.Int J Cancer. 2013 Jan 15;132(2):472-84. doi: 10.1002/ijc.27679. Epub 2012 Jul 9.
77 Identification and allelic frequencies of novel single-nucleotide polymorphisms in the DUSP1 and BTG1 genes.J Hum Genet. 2001;46(3):155-7. doi: 10.1007/s100380170105.
78 Overexpression of HABP1 correlated with clinicopathological characteristics and unfavorable prognosis in endometrial cancer.Tumour Biol. 2015 Feb;36(2):1299-306. doi: 10.1007/s13277-014-2761-8. Epub 2014 Oct 30.
79 Progesterone induces cell apoptosis via the CACNA2D3/Ca2+/p38 MAPK pathway in endometrial cancer.Oncol Rep. 2020 Jan;43(1):121-132. doi: 10.3892/or.2019.7396. Epub 2019 Oct 31.
80 Analysis of candidate target genes for mononucleotide repeat mutation in microsatellite instability-high (MSI-H) endometrial cancer.Int J Oncol. 2009 Nov;35(5):977-82. doi: 10.3892/ijo_00000411.
81 Polymorphisms and haplotypes in the caspase-3, caspase-7, and caspase-8 genes and risk for endometrial cancer: a population-based, case-control study in a Chinese population.Cancer Epidemiol Biomarkers Prev. 2009 Jul;18(7):2114-22. doi: 10.1158/1055-9965.EPI-09-0152. Epub 2009 Jun 16.
82 MicroRNA?95 inhibits epithelialmesenchymal transition by targeting G proteincoupled estrogen receptor 1 in endometrial carcinoma.Mol Med Rep. 2019 Nov;20(5):4023-4032. doi: 10.3892/mmr.2019.10652. Epub 2019 Sep 6.
83 Identification of prognosis markers for endometrial cancer by integrated analysis of DNA methylation and RNA-Seq data.Sci Rep. 2019 Jul 9;9(1):9924. doi: 10.1038/s41598-019-46195-8.
84 Deep and Durable Response With Combination CTLA-4 and PD-1 Blockade in Mismatch Repair (MMR)-proficient Endometrial Cancer.J Immunother. 2019 Feb-Mar;42(2):51-54. doi: 10.1097/CJI.0000000000000244.
85 Identification of Potential Crucial Genes Associated With the Pathogenesis and Prognosis of Endometrial Cancer.Front Genet. 2019 Apr 26;10:373. doi: 10.3389/fgene.2019.00373. eCollection 2019.
86 MiR-449a functions as a tumor suppressor in endometrial cancer by targeting CDC25A.Oncol Rep. 2014 Sep;32(3):1193-9. doi: 10.3892/or.2014.3303. Epub 2014 Jul 3.
87 Alteration of G2 cell cycle regulators occurs during carcinogenesis of the endometrium.Oncology. 2003;65(2):159-66. doi: 10.1159/000072342.
88 hLH/hCG-receptor expression correlates with in vitro invasiveness in human primary endometrial cancer.Gynecol Oncol. 2008 Dec;111(3):496-501. doi: 10.1016/j.ygyno.2008.08.018. Epub 2008 Oct 1.
89 Structure, expression and mutational analysis of the hBRAG gene on 10q in the frequently deleted region in human endometrial cancer.Oncol Rep. 2000 Nov-Dec;7(6):1339-42. doi: 10.3892/or.7.6.1339.
90 Catechol-O-methyltransferase and cytochrome P-450 1B1 polymorphisms and endometrial cancer risk: a meta-analysis.Int J Gynecol Cancer. 2013 Mar;23(3):422-30. doi: 10.1097/IGC.0b013e3182849e0d.
91 Urocortin suppresses endometrial cancer cell migration via CRFR2 and its system components are differentially modulated by estrogen.Cancer Med. 2017 Feb;6(2):408-415. doi: 10.1002/cam4.967. Epub 2017 Jan 21.
92 Chondroitin sulfate proteoglycan protein is stimulated by interleukin11 and promotes endometrial epithelial cancer cell proliferation and migration.Int J Oncol. 2017 Mar;50(3):798-804. doi: 10.3892/ijo.2017.3848. Epub 2017 Jan 13.
93 Hypomethylation of the CTCFL/BORIS promoter and aberrant expression during endometrial cancer progression suggests a role as an Epi-driver gene.Oncotarget. 2014 Feb 28;5(4):1052-61. doi: 10.18632/oncotarget.1697.
94 Immunohistochemical Nuclear Expression of -Catenin as a Surrogate of CTNNB1 Exon 3 Mutation in Endometrial Cancer.Am J Clin Pathol. 2019 Apr 2;151(5):529-538. doi: 10.1093/ajcp/aqy178.
95 Expression of cysteine protease cathepsin L is increased in endometrial cancer and correlates with expression of growth regulatory genes.Cancer Invest. 2012 Jun;30(5):398-403. doi: 10.3109/07357907.2012.672608. Epub 2012 Mar 27.
96 Chemokines mRNA expression in relation to the Macrophage Migration Inhibitory Factor (MIF) mRNA and Vascular Endothelial Growth Factor (VEGF) mRNA expression in the microenvironment of endometrial cancer tissue and normal endometrium: a pilot study.Cytokine. 2013 Nov;64(2):509-15. doi: 10.1016/j.cyto.2013.07.024. Epub 2013 Aug 25.
97 Association between CYP3A4 genotype and risk of endometrial cancer following tamoxifen use.Carcinogenesis. 2007 Oct;28(10):2139-42. doi: 10.1093/carcin/bgm087. Epub 2007 Apr 13.
98 Argininosuccinate Synthase 1-Deficiency Enhances the Cell Sensitivity to Arginine through Decreased DEPTOR Expression in Endometrial Cancer.Sci Rep. 2017 Mar 30;7:45504. doi: 10.1038/srep45504.
99 Diacylglycerol kinase mediates 17--estradiol-induced proliferation, motility, and anchorage-independent growth of Hec-1A endometrial cancer cell line through the G protein-coupled estrogen receptor GPR30.Cell Signal. 2011 Dec;23(12):1988-96. doi: 10.1016/j.cellsig.2011.07.009. Epub 2011 Jul 22.
100 A two-step strategy for identification of plasma protein biomarkers for endometrial and ovarian cancer.Clin Proteomics. 2018 Dec 1;15:38. doi: 10.1186/s12014-018-9216-y. eCollection 2018.
101 Significance of calreticulin as a prognostic factor in endometrial cancer.Oncol Lett. 2018 Jun;15(6):8999-9008. doi: 10.3892/ol.2018.8495. Epub 2018 Apr 13.
102 CD44, TGM2 and EpCAM as novel plasma markers in endometrial cancer diagnosis.BMC Cancer. 2019 Apr 29;19(1):401. doi: 10.1186/s12885-019-5556-x.
103 Dual targeting of estrogen receptor and estrogen-related receptor : a novel endocrine therapy for endometrial cancer.Onco Targets Ther. 2019 Aug 20;12:6757-6767. doi: 10.2147/OTT.S216146. eCollection 2019.
104 The agonist activity of tamoxifen is inhibited by the short heterodimer partner orphan nuclear receptor in human endometrial cancer cells. Endocrinology. 2002 Mar;143(3):853-67.
105 Loss of polarity alters proliferation and differentiation in low-grade endometrial cancers by disrupting Notch signaling.PLoS One. 2017 Dec 5;12(12):e0189081. doi: 10.1371/journal.pone.0189081. eCollection 2017.
106 Inactivation of the candidate tumor suppressor par-4 in endometrial cancer.Cancer Res. 2007 Mar 1;67(5):1927-34. doi: 10.1158/0008-5472.CAN-06-2687.
107 Knocking down FAM83B inhibits endometrial cancer cell proliferation and metastasis by silencing the PI3K/AKT/mTOR pathway.Biomed Pharmacother. 2019 Jul;115:108939. doi: 10.1016/j.biopha.2019.108939. Epub 2019 May 9.
108 Comparative Study of the Effects of Ferrochelatase-siRNA Transfection Mediated by Ultrasound Microbubbles and Polyethyleneimine in Combination with Low-dose ALA to Enhance PpIX Accumulation in Human Endometrial Cancer Xenograft Nude Mice Models.Photochem Photobiol. 2019 Jul;95(4):1045-1051. doi: 10.1111/php.13076. Epub 2019 Feb 11.
109 Expressions of the fibroblast growth factor family (FGF-1, -2 and -4) mRNA in endometrial cancers.Tumour Biol. 1996;17(4):226-33. doi: 10.1159/000217984.
110 FTO expression is associated with the occurrence of gastric cancer and prognosis.Oncol Rep. 2017 Oct;38(4):2285-2292. doi: 10.3892/or.2017.5904. Epub 2017 Aug 14.
111 GALR1 methylation in vaginal swabs is highly accurate in identifying women with endometrial cancer.Int J Gynecol Cancer. 2013 Jul;23(6):1050-5. doi: 10.1097/IGC.0b013e3182959103.
112 Growth hormone-releasing hormone antagonist inhibits the invasiveness of human endometrial cancer cells by down-regulating twist and N-cadherin expression.Oncotarget. 2017 Jan 17;8(3):4410-4421. doi: 10.18632/oncotarget.13877.
113 (99m)Tc-LHRH in tumor receptor imaging.Oncol Lett. 2017 Jul;14(1):569-578. doi: 10.3892/ol.2017.6246. Epub 2017 May 24.
114 GnRH agonist inhibits human telomerase reverse transcriptase mRNA expression in endometrial cancer cells.Int J Mol Med. 2002 Nov;10(5):593-7.
115 Promoter hypermethylation of CIDEA, HAAO and RXFP3 associated with microsatellite instability in endometrial carcinomas.Gynecol Oncol. 2010 May;117(2):239-47. doi: 10.1016/j.ygyno.2010.02.006. Epub 2010 Mar 7.
116 Tumor-associated macrophage-derived CXCL8 could induce ER suppression via HOXB13 in endometrial cancer.Cancer Lett. 2016 Jun 28;376(1):127-36. doi: 10.1016/j.canlet.2016.03.036. Epub 2016 Mar 24.
117 Hepsin inhibits the cell growth of endometrial cancer.Int J Mol Med. 2008 Sep;22(3):389-97.
118 Blocking 17-hydroxysteroid dehydrogenase type 1 in endometrial cancer: a potential novel endocrine therapeutic approach.J Pathol. 2018 Feb;244(2):203-214. doi: 10.1002/path.5004. Epub 2018 Jan 3.
119 Polymorphisms in genes hydroxysteroid-dehydrogenase-17b type 2 and type 4 and endometrial cancer risk.Gynecol Oncol. 2011 Apr;121(1):54-8. doi: 10.1016/j.ygyno.2010.11.014. Epub 2010 Dec 3.
120 Proteomic analysis in endometrial cancer and endometrial hyperplasia tissues by 2D-DIGE technique.J Gynecol Obstet Hum Reprod. 2020 Feb;49(2):101652. doi: 10.1016/j.jogoh.2019.101652. Epub 2019 Nov 26.
121 Discovery and validation of methylation markers for endometrial cancer.Int J Cancer. 2014 Oct 15;135(8):1860-8. doi: 10.1002/ijc.28843. Epub 2014 Mar 31.
122 Suppressed expression of insulin-like growth factor binding protein-1 mRNA in the endometrium: a molecular mechanism associating endometrial cancer with its risk factors.Int J Cancer. 1994 Nov 1;59(3):307-12. doi: 10.1002/ijc.2910590303.
123 Targeting Interleukin-11 Receptor- Impairs Human Endometrial Cancer Cell Proliferation and Invasion In Vitro and Reduces Tumor Growth and Metastasis In Vivo.Mol Cancer Ther. 2016 Apr;15(4):720-30. doi: 10.1158/1535-7163.MCT-15-0677. Epub 2016 Feb 4.
124 KDM4B and KDM4A promote endometrial cancer progression by regulating androgen receptor, c-myc, and p27kip1.Oncotarget. 2015 Oct 13;6(31):31702-20. doi: 10.18632/oncotarget.5165.
125 Expression and clinical significance of KLK5-8 in endometrial cancer.Am J Transl Res. 2019 Jul 15;11(7):4180-4191. eCollection 2019.
126 Keratin 17 is a negative prognostic biomarker in high-grade endometrial carcinomas.Hum Pathol. 2019 Dec;94:40-50. doi: 10.1016/j.humpath.2019.09.005. Epub 2019 Oct 23.
127 Immune inhibitory receptor LILRB2 is critical for the endometrial cancer progression.Biochem Biophys Res Commun. 2018 Nov 17;506(1):243-250. doi: 10.1016/j.bbrc.2018.09.114. Epub 2018 Oct 19.
128 Novel breast cancer risk alleles and endometrial cancer risk.Int J Cancer. 2008 Dec 15;123(12):2961-4. doi: 10.1002/ijc.23862.
129 Multiple loci identified in a genome-wide association study of prostate cancer.Nat Genet. 2008 Mar;40(3):310-5. doi: 10.1038/ng.91. Epub 2008 Feb 10.
130 Deep Infiltrating Endometriosis and Endometrial Adenocarcinoma Express High Levels of Myostatin and Its Receptors Messenger RNAs.Reprod Sci. 2017 Dec;24(12):1577-1582. doi: 10.1177/1933719117698579. Epub 2017 Mar 27.
131 Ramelteon, a selective MT1/MT2 receptor agonist, suppresses the proliferation and invasiveness of endometrial cancer cells.Hum Cell. 2017 Jul;30(3):209-215. doi: 10.1007/s13577-017-0169-7. Epub 2017 Apr 5.
132 Cloning and functional expression of the hNPY Y5 receptor in human endometrial cancer (HEC-1B) cells.Can J Physiol Pharmacol. 2000 Feb;78(2):134-42.
133 Expression of NR1H3 in endometrial carcinoma and its effect on the proliferation of Ishikawa cells in vitro.Onco Targets Ther. 2019 Jan 18;12:685-697. doi: 10.2147/OTT.S180534. eCollection 2019.
134 Expression of NRP-1 and NRP-2 in Endometrial Cancer.Curr Pharm Biotechnol. 2019;20(3):254-260. doi: 10.2174/1389201020666190219121602.
135 Expression of neurotensin receptor 1 in endometrial adenocarcinoma is correlated with histological grade and clinical outcome.Virchows Arch. 2017 Oct;471(4):521-530. doi: 10.1007/s00428-017-2215-y. Epub 2017 Aug 24.
136 Olfactomedin-4 regulation by estrogen in the human endometrium requires epidermal growth factor signaling. Am J Pathol. 2010 Nov;177(5):2495-508. doi: 10.2353/ajpath.2010.100026.
137 Expression and responsiveness of P2Y2 receptors in human endometrial cancer cell lines.J Clin Endocrinol Metab. 1999 Nov;84(11):4085-91. doi: 10.1210/jcem.84.11.6119.
138 Proprotein convertases in post-menopausal endometrial cancer: distinctive regulation and non-invasive diagnosis.Biochem Biophys Res Commun. 2012 Mar 23;419(4):809-14. doi: 10.1016/j.bbrc.2012.02.111. Epub 2012 Feb 27.
139 Over-expression of platelet-derived growth factor-D promotes tumor growth and invasion in endometrial cancer.Int J Mol Sci. 2014 Mar 18;15(3):4780-94. doi: 10.3390/ijms15034780.
140 Pepsinogen C expression, regulation and its relationship with cancer.Cancer Cell Int. 2017 May 23;17:57. doi: 10.1186/s12935-017-0426-6. eCollection 2017.
141 Negative regulation of AMPK1 by PIM2 promotes aerobic glycolysis and tumorigenesis in endometrial cancer.Oncogene. 2019 Sep;38(38):6537-6549. doi: 10.1038/s41388-019-0898-z. Epub 2019 Jul 29.
142 Individualised proteome profiling of human endometrial tumours improves detection of new prognostic markers.Br J Cancer. 2013 Aug 6;109(3):704-13. doi: 10.1038/bjc.2013.359. Epub 2013 Jul 9.
143 Laparoendoscopic Single-Site Sentinel Lymph Node Detection in Endometrial Cancer.J Minim Invasive Gynecol. 2018 Jul-Aug;25(5):776. doi: 10.1016/j.jmig.2017.10.035. Epub 2017 Nov 13.
144 Genomic Comparison of Endometrioid Endometrial Carcinoma and Its Precancerous Lesions in Chinese Patients by High-Depth Next Generation Sequencing.Front Oncol. 2019 Mar 4;9:123. doi: 10.3389/fonc.2019.00123. eCollection 2019.
145 Serum Prolactin Contributes to Enhancing Prolactin Receptor and pJAK2 in Type I Endometrial Cancer Cells in Young Women Without Insulin Resistance.Int J Gynecol Pathol. 2019 Jul;38(4):318-325. doi: 10.1097/PGP.0000000000000527.
146 Genetic variants in ER cofactor genes and endometrial cancer risk.PLoS One. 2012;7(8):e42445. doi: 10.1371/journal.pone.0042445. Epub 2012 Aug 2.
147 Gefitinib enhances sensitivity of endometrial cancer cells to progestin therapy via dual-specificity phosphatase 1.Oncotarget. 2017 Dec 15;8(70):115360-115369. doi: 10.18632/oncotarget.23264. eCollection 2017 Dec 29.
148 RICTOR expression in esophageal squamous cell carcinoma and its clinical significance.Med Oncol. 2017 Mar;34(3):32. doi: 10.1007/s12032-017-0894-5. Epub 2017 Jan 28.
149 ROR1 and ROR2 play distinct and opposing roles in endometrial cancer.Gynecol Oncol. 2018 Mar;148(3):576-584. doi: 10.1016/j.ygyno.2018.01.025. Epub 2018 Feb 1.
150 Relaxin 2/RXFP1 Signaling Induces Cell Invasion via the -Catenin Pathway in Endometrial Cancer.Int J Mol Sci. 2018 Aug 18;19(8):2438. doi: 10.3390/ijms19082438.
151 Expression of SCUBE2 gene declines in high grade endometrial cancer and associates with expression of steroid hormone receptors and tumor suppressor PTEN.Gynecol Endocrinol. 2013 Dec;29(12):1031-5. doi: 10.3109/09513590.2013.829441. Epub 2013 Sep 20.
152 Effects of sex steroid hormones on corticosteroid-binding globulin gene expression in human endometrial cancer cell line Ishikawa.Ann Clin Biochem. 1998 Sep;35 ( Pt 5):637-42. doi: 10.1177/000456329803500507.
153 Endometrial cancer surveillance adherence reduces utilization and subsequent costs.Gynecol Oncol. 2017 Sep;146(3):514-518. doi: 10.1016/j.ygyno.2017.06.024. Epub 2017 Jul 19.
154 A small compound spindlactone A sensitizes human endometrial cancer cells to TRAIL-induced apoptosis via the inhibition of NAD(P)H dehydrogenase quinone 1.Onco Targets Ther. 2018 Jun 21;11:3609-3617. doi: 10.2147/OTT.S165723. eCollection 2018.
155 CD47 Blockade Inhibits Tumor Progression through Promoting Phagocytosis of Tumor Cells by M2 Polarized Macrophages in Endometrial Cancer.J Immunol Res. 2018 Nov 7;2018:6156757. doi: 10.1155/2018/6156757. eCollection 2018.
156 Assessing sirtuin expression in endometrial carcinoma and non-neoplastic endometrium.Oncotarget. 2016 Jan 12;7(2):1144-54. doi: 10.18632/oncotarget.6691.
157 Negative Effect of Ellagic Acid on Cytosolic pH Regulation and Glycolytic Flux in Human Endometrial Cancer Cells.Cell Physiol Biochem. 2017;41(6):2374-2382. doi: 10.1159/000475655. Epub 2017 Apr 27.
158 SOX15 regulates proliferation and migration of endometrial cancer cells.Biosci Rep. 2017 Oct 17;37(5):BSR20171045. doi: 10.1042/BSR20171045. Print 2017 Oct 31.
159 Stanniocalcin-2 May Be a Potentially Valuable Prognostic Marker in Endometrial Cancer: a Preliminary Study.Pathol Oncol Res. 2019 Apr;25(2):751-757. doi: 10.1007/s12253-018-00576-y. Epub 2019 Jan 19.
160 Six-transmembrane epithelial antigen of the prostate 1 is associated with tumor invasion and migration in endometrial carcinomas.J Cell Biochem. 2019 Jul;120(7):11172-11189. doi: 10.1002/jcb.28393. Epub 2019 Feb 3.
161 Receptor Activator of Nuclear Factor Kappa B (RANK) and Clinicopathological Variables in Endometrial Cancer: A Study at Protein and Gene Level.Int J Mol Sci. 2018 Jun 22;19(7):1848. doi: 10.3390/ijms19071848.
162 TWEAK/Fn14 promotes apoptosis of human endometrial cancer cells via caspase pathway.Cancer Lett. 2010 Aug 1;294(1):91-100. doi: 10.1016/j.canlet.2010.01.027. Epub 2010 Feb 26.
163 Mutational analysis of the tyrosine kinome in serous and clear cell endometrial cancer uncovers rare somatic mutations in TNK2 and DDR1.BMC Cancer. 2014 Nov 26;14:884. doi: 10.1186/1471-2407-14-884.
164 Telomere length and genetic analyses in population-based studies of endometrial cancer risk.Cancer. 2010 Sep 15;116(18):4275-82. doi: 10.1002/cncr.25328.
165 Topoisomerase II binding protein 1 c.*229C>T (rs115160714) gene polymorphism and endometrial cancer risk.Pathol Oncol Res. 2014 Jul;20(3):597-602. doi: 10.1007/s12253-013-9737-7. Epub 2013 Dec 18.
166 Role of the tripartite motif protein 27 in cancer development.J Natl Cancer Inst. 2012 Jun 20;104(12):941-52. doi: 10.1093/jnci/djs224. Epub 2012 May 3.
167 miR-214-3p inhibits epithelial-to-mesenchymal transition and metastasis of endometrial cancer cells by targeting TWIST1.Onco Targets Ther. 2019 Nov 18;12:9449-9458. doi: 10.2147/OTT.S181037. eCollection 2019.
168 Genetic variation in CYP17A1 and pancreatic cancer in a population-based case-control study in the San Francisco Bay Area, California.Int J Cancer. 2010 Feb 1;126(3):790-5. doi: 10.1002/ijc.24792.
169 VISTA expressed in tumour cells regulates T cell function.Br J Cancer. 2019 Jan;120(1):115-127. doi: 10.1038/s41416-018-0313-5. Epub 2018 Nov 9.
170 Long Non-coding RNA CDKN2B Antisense RNA 1 Gene Contributes to Paclitaxel Resistance in Endometrial Carcinoma.Front Oncol. 2019 Jan 29;9:27. doi: 10.3389/fonc.2019.00027. eCollection 2019.
171 Metformin sensitizes endometrial cancer cells to progestin by targeting TET1 to downregulate glyoxalase I expression.Biomed Pharmacother. 2019 May;113:108712. doi: 10.1016/j.biopha.2019.108712. Epub 2019 Mar 6.
172 Quantitative RT-PCR Assay for Detecting Lymph Node Metastasis in Endometrial Cancer: A Preliminary Study.Oncology. 2019;96(4):179-182. doi: 10.1159/000493485. Epub 2018 Nov 14.
173 Identification of new fusion genes and their clinical significance in endometrial cancer.Chin Med J (Engl). 2019 Jun 5;132(11):1314-1321. doi: 10.1097/CM9.0000000000000203.
174 Knockout of glucose transporter GLUT6 has minimal effects on whole body metabolic physiology in mice.Am J Physiol Endocrinol Metab. 2018 Aug 1;315(2):E286-E293. doi: 10.1152/ajpendo.00082.2018. Epub 2018 Apr 17.
175 STAR and AKR1B10 are down-regulated in high-grade endometrial cancer.J Steroid Biochem Mol Biol. 2017 Jul;171:43-53. doi: 10.1016/j.jsbmb.2017.02.015. Epub 2017 Feb 21.
176 Mechanism of progestin resistance in endometrial precancer/cancer through Nrf2-AKR1C1 pathway.Oncotarget. 2016 Mar 1;7(9):10363-72. doi: 10.18632/oncotarget.7004.
177 Preoperative frailty is a risk factor for non-home discharge in patients undergoing surgery for endometrial cancer.J Geriatr Oncol. 2018 Sep;9(5):513-515. doi: 10.1016/j.jgo.2018.02.005. Epub 2018 Mar 9.
178 BAT-26 microsatellite instability does not correlate with the loss of hMLH1 and hMSH2 protein expression in sporadic endometrial cancers.Oncol Rep. 2003 Jul-Aug;10(4):1039-43.
179 Loss of heterozygosity of BRCA1, TP53 and TCRD markers analysed in sporadic endometrial cancer.Eur J Cancer. 1998 Oct;34(11):1770-6. doi: 10.1016/s0959-8049(98)00270-6.
180 GGC and StuI polymorphism on the androgen receptor gene in endometrial cancer patients.Biochem Biophys Res Commun. 2005 Apr 1;329(1):100-4. doi: 10.1016/j.bbrc.2005.01.104.
181 Abnormal expression of period 1 (PER1) in endometrial carcinoma.J Pathol. 2005 May;206(1):111-20. doi: 10.1002/path.1756.
182 Function of UDP-glucuronosyltransferase 2B17 (UGT2B17) is involved in endometrial cancer.Carcinogenesis. 2010 Sep;31(9):1620-6. doi: 10.1093/carcin/bgq124. Epub 2010 Jun 16.
183 Genetic variations in UGT1A1 and UGT2B7 and endometrial cancer risk.Pharmacogenet Genomics. 2009 Mar;19(3):239-43. doi: 10.1097/FPC.0b013e328323f66c.
184 Acrp30 inhibits leptin-induced metastasis by downregulating the JAK/STAT3 pathway via AMPK activation in aggressive SPEC-2 endometrial cancer cells.Oncol Rep. 2012 May;27(5):1488-96. doi: 10.3892/or.2012.1670. Epub 2012 Feb 2.
185 Utility of diffusion-weighted imaging in association with pathologic upgrading in biopsy-proven grade I endometrial cancer.J Magn Reson Imaging. 2020 Jan;51(1):117-123. doi: 10.1002/jmri.26840. Epub 2019 Jun 17.
186 Mutual suppression between BHLHE40/BHLHE41 and the MIR301B-MIR130B cluster is involved in epithelial-to-mesenchymal transition of endometrial cancer cells.Oncotarget. 2019 Jul 23;10(45):4640-4654. doi: 10.18632/oncotarget.27061. eCollection 2019 Jul 23.
187 The relationships between the immunoexpression of KAI1, MMP-2, MMP-9 and steroid receptors expression in endometrial cancer.Folia Histochem Cytobiol. 2014;52(3):187-94. doi: 10.5603/FHC.2014.0022.
188 Rearrangement and allelic imbalance on chromosome 5 leads to homozygous deletions in the CDKN2A/2B tumor suppressor gene region in rat endometrial cancer.Cancer Genet Cytogenet. 2008 Jul;184(1):9-21. doi: 10.1016/j.cancergencyto.2008.02.016.
189 CHD4 mutations promote endometrial cancer stemness by activating TGF-beta signaling.Am J Cancer Res. 2018 May 1;8(5):903-914. eCollection 2018.
190 RNA interference targeting CHFR enhances taxol chemosensitivity in endometrial cancer cells.Oncol Rep. 2012 Jul;28(1):248-54. doi: 10.3892/or.2012.1752. Epub 2012 Apr 2.
191 CTCF Expression is Essential for Somatic Cell Viability and Protection Against Cancer.Int J Mol Sci. 2018 Nov 30;19(12):3832. doi: 10.3390/ijms19123832.
192 CTHRC1 promotes M2-like macrophage recruitment and myometrial invasion in endometrial carcinoma by integrin-Akt signaling pathway.Clin Exp Metastasis. 2019 Aug;36(4):351-363. doi: 10.1007/s10585-019-09971-4. Epub 2019 May 22.
193 Expression of receptor-binding cancer antigen expressed on SiSo cells and estrogen receptor subtypes in the normal, hyperplastic, and carcinomatous endometrium.Int J Gynecol Cancer. 2008 Jan-Feb;18(1):152-8. doi: 10.1111/j.1525-1438.2007.00966.x. Epub 2007 Apr 26.
194 The R156R ERCC2 polymorphism as a risk factor of endometrial cancer.Tumour Biol. 2016 Feb;37(2):2171-6. doi: 10.1007/s13277-015-4040-8. Epub 2015 Sep 9.
195 Mutations and amplification of oncogenes in endometrial cancer.Oncology. 1999;56(1):59-65. doi: 10.1159/000011931.
196 Generation of Mouse for Conditional Expression of Forkhead Box A2.Endocrinology. 2018 Apr 1;159(4):1897-1909. doi: 10.1210/en.2018-00158.
197 Tumor-suppressor role of miR-139-5p in endometrial cancer.Cancer Cell Int. 2018 Apr 2;18:51. doi: 10.1186/s12935-018-0545-8. eCollection 2018.
198 HNRNP G and HTRA2-BETA1 regulate estrogen receptor alpha expression with potential impact on endometrial cancer.BMC Cancer. 2015 Feb 27;15:86. doi: 10.1186/s12885-015-1088-1.
199 Krppel-like factor 9 loss-of-expression in human endometrial carcinoma links altered expression of growth-regulatory genes with aberrant proliferative response to estrogen.Biol Reprod. 2011 Aug;85(2):378-85. doi: 10.1095/biolreprod.110.090654. Epub 2011 May 4.
200 Down-regulation of Sox7 is associated with aberrant activation of Wnt/b-catenin signaling in endometrial cancer.Oncotarget. 2012 Dec;3(12):1546-56. doi: 10.18632/oncotarget.667.
201 Loss of tricellular tight junction protein LSR promotes cell invasion and migration via upregulation of TEAD1/AREG in human endometrial cancer.Sci Rep. 2017 Jan 10;7:37049. doi: 10.1038/srep37049.
202 Matrix metalloproteinase-26 (matrilysin-2) expression is high in endometrial hyperplasia and decreases with loss of histological differentiation in endometrial cancer.Gynecol Oncol. 2004 Sep;94(3):661-70. doi: 10.1016/j.ygyno.2004.05.024.
203 Nucleobindin 2 (NUCB2) in human endometrial carcinoma: a potent prognostic factor associated with cell proliferation and migration.Endocr J. 2016;63(3):287-99. doi: 10.1507/endocrj.EJ15-0490. Epub 2016 Feb 4.
204 Downregulation of PDCD4 induced by progesterone is mediated by the PI3K/AKT signaling pathway in human endometrial cancer cells.Oncol Rep. 2019 Aug;42(2):849-856. doi: 10.3892/or.2019.7202. Epub 2019 Jun 18.
205 Precision Therapy for Aggressive Endometrial Cancer by Reactivation of Protein Phosphatase 2A.Cancer Res. 2019 Aug 15;79(16):4009-4010. doi: 10.1158/0008-5472.CAN-19-1938.
206 Endocrine gland-derived vascular endothelial growth factor is expressed in human peri-implantation endometrium, but not in endometrial carcinoma.Endocrinology. 2006 Jan;147(1):88-95. doi: 10.1210/en.2005-0543. Epub 2005 Oct 6.
207 Potential of RASSF1A promoter methylation as biomarker for endometrial cancer: A systematic review and meta-analysis.Gynecol Oncol. 2017 Sep;146(3):603-608. doi: 10.1016/j.ygyno.2017.06.017. Epub 2017 Jun 29.
208 Role of ribosomal protein mutations in tumor development (Review).Int J Oncol. 2016 Apr;48(4):1313-24. doi: 10.3892/ijo.2016.3387. Epub 2016 Feb 9.
209 Mig-6 Mouse Model of Endometrial Cancer.Adv Exp Med Biol. 2017;943:243-259. doi: 10.1007/978-3-319-43139-0_8.
210 The utility of sentinel lymph node mapping in the management of endometrial atypical hyperplasia.Gynecol Oncol. 2018 Mar;148(3):485-490. doi: 10.1016/j.ygyno.2017.12.026. Epub 2017 Dec 28.
211 MicroRNA?09 may function as a tumor suppressor in endometrial carcinoma cells by targeting Smad2.Mol Med Rep. 2019 Jan;19(1):622-628. doi: 10.3892/mmr.2018.9642. Epub 2018 Nov 12.
212 Molecular markers of endometrial carcinoma detected in uterine aspirates.Int J Cancer. 2011 Nov 15;129(10):2435-44. doi: 10.1002/ijc.25901. Epub 2011 Apr 8.
213 SOX17 in cellular reprogramming and cancer.Semin Cancer Biol. 2020 Dec;67(Pt 1):65-73. doi: 10.1016/j.semcancer.2019.08.008. Epub 2019 Aug 13.
214 Prostaglandin E2 (PGE2) promotes proliferation and invasion by enhancing SUMO-1 activity via EP4 receptor in endometrial cancer.Tumour Biol. 2016 Sep;37(9):12203-12211. doi: 10.1007/s13277-016-5087-x. Epub 2016 May 26.
215 Significance of TGFBR3 allelic loss in the deregulation of TGF signaling in primary human endometrial carcinomas.Oncol Rep. 2016 Feb;35(2):932-8. doi: 10.3892/or.2015.4400. Epub 2015 Nov 5.
216 Silencing of the icb-1 gene inhibits the induction of differentiation-associated genes by vitamin D3 and all-trans retinoic acid in gynecological cancer cells.Int J Mol Med. 2011 Jul;28(1):121-7. doi: 10.3892/ijmm.2011.663. Epub 2011 Mar 31.
217 Expressions and significances of TTF-1 and PTEN in early endometrial cancer.Eur Rev Med Pharmacol Sci. 2017 Jul;21(3 Suppl):20-26.
218 Cyr61, a member of ccn (connective tissue growth factor/cysteine-rich 61/nephroblastoma overexpressed) family, predicts survival of patients with endometrial cancer of endometrioid subtype.Gynecol Oncol. 2009 Jan;112(1):229-34. doi: 10.1016/j.ygyno.2008.09.039. Epub 2008 Nov 12.
219 Clinical and Expression Significance of AKT1 by Co-expression Network Analysis in Endometrial Cancer.Front Oncol. 2019 Nov 6;9:1147. doi: 10.3389/fonc.2019.01147. eCollection 2019.
220 Combined genetic mutations and DNA-methylated genes as biomarkers for endometrial cancer detection from cervical scrapings.Clin Epigenetics. 2019 Nov 28;11(1):170. doi: 10.1186/s13148-019-0765-3.
221 Leupaxin is expressed in mammary carcinoma and acts as a transcriptional activator of the estrogen receptor .Int J Oncol. 2015 Jul;47(1):106-14. doi: 10.3892/ijo.2015.2988. Epub 2015 May 6.
222 Overexpression of peroxiredoxin-3 and -5 is a potential biomarker for prognosis in endometrial cancer.Oncol Lett. 2018 Apr;15(4):5111-5118. doi: 10.3892/ol.2018.7909. Epub 2018 Jan 31.
223 Changes in Expression Pattern of SEMA3F Depending on Endometrial Cancer Grade - Pilot Study.Curr Pharm Biotechnol. 2019;20(9):727-732. doi: 10.2174/1389201020666190619145655.
224 Sirtuin-7 knockdown inhibits the growth of endometrial cancer cells by inducing apoptosis via the NF-B signaling pathway.Oncol Lett. 2019 Jan;17(1):937-943. doi: 10.3892/ol.2018.9698. Epub 2018 Nov 14.
225 MicroRNA-23a inhibits endometrial cancer cell development by targeting SIX1.Oncol Lett. 2019 Oct;18(4):3792-3802. doi: 10.3892/ol.2019.10694. Epub 2019 Jul 31.
226 Mitochondrial supercomplex assembly promotes breast and endometrial tumorigenesis by metabolic alterations and enhanced hypoxia tolerance.Nat Commun. 2019 Sep 11;10(1):4108. doi: 10.1038/s41467-019-12124-6.
227 Expression of DCC and netrin-1 in normal human endometrium and its implication in endometrial carcinogenesis.Gynecol Oncol. 2004 Nov;95(2):281-9. doi: 10.1016/j.ygyno.2004.07.050.
228 EMP2 is a novel therapeutic target for endometrial cancer stem cells.Oncogene. 2017 Oct 19;36(42):5793-5807. doi: 10.1038/onc.2017.142. Epub 2017 Jun 12.
229 Comparative Cistromics Reveals Genomic Cross-talk between FOXA1 and ER in Tamoxifen-Associated Endometrial Carcinomas.Cancer Res. 2016 Jul 1;76(13):3773-84. doi: 10.1158/0008-5472.CAN-14-1813. Epub 2016 May 6.
230 New routes to old places: PIK3R1 and PIK3R2 join PIK3CA and PTEN as endometrial cancer genes.Cancer Discov. 2011 Jul;1(2):106-7. doi: 10.1158/2159-8290.CD-11-0116.
231 Rap1GAP inhibits tumor progression in endometrial cancer.Biochem Biophys Res Commun. 2017 Apr 1;485(2):476-483. doi: 10.1016/j.bbrc.2017.02.044. Epub 2017 Feb 11.
232 Mammaglobin B expression in human endometrial cancer.Int J Gynecol Cancer. 2008 Sep-Oct;18(5):1090-6. doi: 10.1111/j.1525-1438.2007.01137.x. Epub 2007 Nov 16.
233 MicroRNA-449a Inhibits Tumor Metastasis through AKT/ERK1/2 Inactivation by Targeting Steroid Receptor Coactivator (SRC) in Endometrial Cancer.J Cancer. 2019 Jan 1;10(2):547-555. doi: 10.7150/jca.27748. eCollection 2019.
234 LKB1 loss promotes endometrial cancer progression via CCL2-dependent macrophage recruitment.J Clin Invest. 2015 Nov 2;125(11):4063-76. doi: 10.1172/JCI82152. Epub 2015 Sep 28.
235 Can ABCF2 protein expression predict the prognosis of uterine cancer?.Br J Cancer. 2008 Nov 18;99(10):1651-5. doi: 10.1038/sj.bjc.6604734.
236 Oncogenic role of ABHD5 in endometrial cancer.Cancer Manag Res. 2019 Mar 14;11:2139-2150. doi: 10.2147/CMAR.S188648. eCollection 2019.
237 Metabolomic and Lipidomic Profiling Identifies The Role of the RNA Editing Pathway in Endometrial Carcinogenesis.Sci Rep. 2017 Aug 18;7(1):8803. doi: 10.1038/s41598-017-09169-2.
238 MiR-218 suppresses metastasis and invasion of endometrial cancer via negatively regulating ADD2.Eur Rev Med Pharmacol Sci. 2019 Feb;23(4):1408-1417. doi: 10.26355/eurrev_201902_17097.
239 G-protein coupled receptor 64 (GPR64) acts as a tumor suppressor in endometrial cancer.BMC Cancer. 2019 Aug 14;19(1):810. doi: 10.1186/s12885-019-5998-1.
240 Adenylosuccinate lyase enhances aggressiveness of endometrial cancer by increasing killer cell lectin-like receptor C3 expression by fumarate.Lab Invest. 2018 Apr;98(4):449-461. doi: 10.1038/s41374-017-0017-0. Epub 2018 Feb 21.
241 Loss of AF-6/afadin induces cell invasion, suppresses the formation of glandular structures and might be a predictive marker of resistance to chemotherapy in endometrial cancer.BMC Cancer. 2015 Apr 12;15:275. doi: 10.1186/s12885-015-1286-x.
242 AMG 479, a novel IGF-1-R antibody, inhibits endometrial cancer cell proliferation through disruption of the PI3K/Akt and MAPK pathways.Reprod Sci. 2011 Sep;18(9):832-41. doi: 10.1177/1933719111398501.
243 Anti-Mllerian Hormone Expression in Endometrial Cancer Tissue.Int J Mol Sci. 2019 Mar 15;20(6):1325. doi: 10.3390/ijms20061325.
244 Estrogen receptor alpha activates MAPK signaling pathway to promote the development of endometrial cancer.J Cell Biochem. 2019 Oct;120(10):17593-17601. doi: 10.1002/jcb.29027. Epub 2019 May 29.
245 AQP2 is regulated by estradiol in human endometrium and is associated with spheroid attachment invitro.Mol Med Rep. 2019 Aug;20(2):1306-1312. doi: 10.3892/mmr.2019.10338. Epub 2019 Jun 5.
246 Trocar site hernia development in patients undergoing robotically assisted or standard laparoscopic staging surgery for endometrial cancer.Gynecol Oncol. 2017 Nov;147(2):371-374. doi: 10.1016/j.ygyno.2017.09.005. Epub 2017 Sep 22.
247 Cytochrome P450 1A1 gene polymorphisms and endometrial cancer risk: a meta-analysis.Int J Gynecol Cancer. 2011 Feb;21(2):323-31. doi: 10.1097/IGC.0b013e31820575c0.
248 Expression of renin-angiotensin system (RAS) components in endometrial cancer.Endocr Connect. 2017 Jan;6(1):9-19. doi: 10.1530/EC-16-0082. Epub 2016 Dec 12.
249 Expression of gastrin-releasing peptide receptors in endometrial cancer.J Am Coll Surg. 2003 Jun;196(6):898-904. doi: 10.1016/S1072-7515(03)00290-4.
250 Chromatin remodelling and DNA repair genes are frequently mutated in endometrioid endometrial carcinoma.Int J Cancer. 2017 Apr 1;140(7):1551-1563. doi: 10.1002/ijc.30573. Epub 2017 Feb 2.
251 Colorectal and Endometrial Cancer Risk and Age at Diagnosis in BLMAsh Mutation Carriers.Isr Med Assoc J. 2017 Jun;19(6):365-367.
252 The Role of Sialyl-Tn in Cancer.Int J Mol Sci. 2016 Feb 24;17(3):275. doi: 10.3390/ijms17030275.
253 Expression of calbindin-D28k is inversely correlated with proapototic gene expression in hydrogen peroxide-induced cell death in endometrial cancer cells.Int J Oncol. 2011 Apr;38(4):1059-66. doi: 10.3892/ijo.2011.916. Epub 2011 Jan 21.
254 Targeted Proteomics Identifies Proteomic Signatures in Liquid Biopsies of the Endometrium to Diagnose Endometrial Cancer and Assist in the Prediction of the Optimal Surgical Treatment.Clin Cancer Res. 2017 Nov 1;23(21):6458-6467. doi: 10.1158/1078-0432.CCR-17-0474. Epub 2017 Aug 8.
255 Genetic polymorphism of PRKCDBP is associated with an increased risk of endometrial cancer.Cancer Invest. 2012 Nov;30(9):642-5. doi: 10.3109/07357907.2012.727054. Epub 2012 Sep 28.
256 Expression of human Biot2 and its potential function on carcinogenesis in endometrial cancer.Acta Obstet Gynecol Scand. 2007;86(12):1503-9. doi: 10.1080/00016340701736946.
257 Culture characters, genetic background, estrogen/progesterone receptor expression, and tumorigenic activities of frequently used sixteen endometrial cancer cell lines.Clin Chim Acta. 2019 Feb;489:225-232. doi: 10.1016/j.cca.2018.08.013. Epub 2018 Aug 11.
258 Potential new biomarkers for endometrial cancer.Cancer Cell Int. 2019 Jan 21;19:19. doi: 10.1186/s12935-019-0731-3. eCollection 2019.
259 Integrated Epigenomics Analysis Reveals a DNA Methylation Panel for Endometrial Cancer Detection Using Cervical Scrapings.Clin Cancer Res. 2017 Jan 1;23(1):263-272. doi: 10.1158/1078-0432.CCR-16-0863. Epub 2016 Aug 9.
260 CGRRF1 as a novel biomarker of tissue response to metformin in the context of obesity.Gynecol Oncol. 2014 Apr;133(1):83-9. doi: 10.1016/j.ygyno.2013.12.006.
261 Long noncoding RNA CHL1-AS1 promotes cell proliferation and migration by sponging miR-6076 to regulate CHL1 expression in endometrial cancer.J Cell Biochem. 2020 Mar;121(3):2655-2663. doi: 10.1002/jcb.29486. Epub 2019 Nov 17.
262 Cold-inducible RNA-binding protein contributes to human antigen R and cyclin E1 deregulation in breast cancer.Mol Carcinog. 2010 Feb;49(2):130-40. doi: 10.1002/mc.20582.
263 Overexpression of claudin-3 and claudin-4 receptors in uterine serous papillary carcinoma: novel targets for a type-specific therapy using Clostridium perfringens enterotoxin (CPE).Cancer. 2007 Apr 1;109(7):1312-22. doi: 10.1002/cncr.22536.
264 Downregulation of lipolysis-stimulated lipoprotein receptor promotes cell invasion via claudin-1-mediated matrix metalloproteinases in human endometrial cancer.Oncol Lett. 2017 Dec;14(6):6776-6782. doi: 10.3892/ol.2017.7038. Epub 2017 Sep 22.
265 Quantitative DNA methylation analysis of selected genes in endometrial carcinogenesis.Taiwan J Obstet Gynecol. 2015 Oct;54(5):572-9. doi: 10.1016/j.tjog.2015.08.010.
266 miR-152 is a tumor suppressor microRNA that is silenced by DNA hypermethylation in endometrial cancer.Cancer Res. 2011 Oct 15;71(20):6450-62. doi: 10.1158/0008-5472.CAN-11-0364. Epub 2011 Aug 25.
267 MicroRNA-183 induces epithelial-mesenchymal transition and promotes endometrial cancer cell migration and invasion in by targeting CPEB1.J Cell Biochem. 2018 Nov;119(10):8123-8137. doi: 10.1002/jcb.26763. Epub 2018 Jun 20.
268 HE4 transcription- and splice variants-specific expression in endometrial cancer and correlation with patient survival.Int J Mol Sci. 2013 Nov 18;14(11):22655-77. doi: 10.3390/ijms141122655.
269 Disabled-1 is a large common fragile site gene, inactivated in multiple cancers.Genes Chromosomes Cancer. 2008 Feb;47(2):165-74. doi: 10.1002/gcc.20519.
270 Expression and clinical significance of the transforming growth factor- signalling pathway in endometrial cancer.Histopathology. 2011 Jul;59(1):63-72. doi: 10.1111/j.1365-2559.2011.03892.x.
271 A mononucleotide repeat in PRRT2 is an important, frequent target of mismatch repair deficiency in cancer.Oncotarget. 2017 Jan 24;8(4):6043-6056. doi: 10.18632/oncotarget.13464.
272 Epigenetic regulation of DACH1, a novel Wnt signaling component in colorectal cancer.Epigenetics. 2013 Dec;8(12):1373-83. doi: 10.4161/epi.26781. Epub 2013 Oct 22.
273 Gene expression profiling in Ishikawa cells: a fingerprint for estrogen active compounds. Toxicol Appl Pharmacol. 2009 Apr 1;236(1):85-96.
274 Endometrial miR-181a and miR-98 expression is altered during transition from normal into cancerous state and target PGR, PGRMC1, CYP19A1, DDX3X, and TIMP3.J Clin Endocrinol Metab. 2012 Jul;97(7):E1316-26. doi: 10.1210/jc.2012-1018. Epub 2012 Apr 6.
275 Frequent immune responses to a cancer/testis antigen, CAGE, in patients with microsatellite instability-positive endometrial cancer.Clin Cancer Res. 2005 May 15;11(10):3949-57. doi: 10.1158/1078-0432.CCR-04-1702.
276 Exome-Wide Rare Variant Analysis From the DiscovEHR Study Identifies Novel Candidate Predisposition Genes for Endometrial Cancer.Front Oncol. 2019 Jul 5;9:574. doi: 10.3389/fonc.2019.00574. eCollection 2019.
277 Identification of a potential prognostic lncRNA-miRNA-mRNA signature in endometrial cancer based on the competing endogenous RNA network.J Cell Biochem. 2019 Nov;120(11):18845-18853. doi: 10.1002/jcb.29200. Epub 2019 Jul 24.
278 Major regulators of microRNAs biogenesis Dicer and Drosha are down-regulated in endometrial cancer.Tumour Biol. 2011 Aug;32(4):769-76. doi: 10.1007/s13277-011-0179-0. Epub 2011 May 11.
279 Dusp6 inhibits epithelial-mesenchymal transition in endometrial adenocarcinoma via ERK signaling pathway.Radiol Oncol. 2019 Sep 24;53(3):307-315. doi: 10.2478/raon-2019-0034.
280 Co-regulatory expression quantitative trait loci mapping: method and application to endometrial cancer.BMC Med Genomics. 2011 Jan 12;4:6. doi: 10.1186/1755-8794-4-6.
281 MicroRNA-424 may function as a tumor suppressor in endometrial carcinoma cells by targeting E2F7.Oncol Rep. 2015 May;33(5):2354-60. doi: 10.3892/or.2015.3812. Epub 2015 Feb 20.
282 Evaluation of Changes in the Expression Pattern of EDIL3 in Different Grades of Endometrial Cancer.Curr Pharm Biotechnol. 2019;20(6):483-488. doi: 10.2174/1389201020666190408112822.
283 The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer.Int J Mol Sci. 2019 Dec 6;20(24):6169. doi: 10.3390/ijms20246169.
284 Association of thymidylate synthase gene with endometrial cancer risk in a Chinese population.Cancer Epidemiol Biomarkers Prev. 2009 Feb;18(2):579-84. doi: 10.1158/1055-9965.EPI-08-0831. Epub 2009 Feb 3.
285 miR-148b Functions as a Tumor Suppressor by Targeting Endoplasmic Reticulum Metallo Protease 1 in Human Endometrial Cancer Cells.Oncol Res. 2018 Dec 27;27(1):81-88. doi: 10.3727/096504018X15202988139874. Epub 2018 Mar 9.
286 Nidogen 1 and Nuclear Protein 1: novel targets of ETV5 transcription factor involved in endometrial cancer invasion.Clin Exp Metastasis. 2015 Jun;32(5):467-78. doi: 10.1007/s10585-015-9720-7. Epub 2015 Apr 30.
287 FAT4-USP51 complex regulates the proliferation and invasion of endometrial cancer via Hippo pathway.Am J Transl Res. 2019 May 15;11(5):2784-2800. eCollection 2019.
288 Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade.Cancer Invest. 2016;34(1):26-31. doi: 10.3109/07357907.2015.1084313. Epub 2015 Dec 18.
289 In silico, in vitro and in vivo analysis identifies a potential role for steroid hormone regulation of FOXD3 in endometriosis-associated genes.Hum Reprod. 2016 Feb;31(2):345-54. doi: 10.1093/humrep/dev307. Epub 2015 Dec 23.
290 YAP/TAZ-Mediated Upregulation of GAB2 Leads to Increased Sensitivity to Growth Factor-Induced Activation of the PI3K Pathway.Cancer Res. 2017 Apr 1;77(7):1637-1648. doi: 10.1158/0008-5472.CAN-15-3084. Epub 2017 Feb 15.
291 The role of hepatocyte growth factor activator inhibitor (HAI)-1 and HAI-2 in endometrial cancer.Int J Cancer. 2011 Jun 1;128(11):2613-24. doi: 10.1002/ijc.25606. Epub 2010 Oct 4.
292 Evaluating Myometrial Invasion in Endometrial Cancer: Comparison of Reduced Field-of-view Diffusion-weighted Imaging and Dynamic Contrast-enhanced MR Imaging.Magn Reson Med Sci. 2018 Jan 10;17(1):28-34. doi: 10.2463/mrms.mp.2016-0128. Epub 2017 May 18.
293 Joint Effect of Genotypic and Phenotypic Features of Reproductive Factors on Endometrial Cancer Risk.Sci Rep. 2015 Oct 26;5:15582. doi: 10.1038/srep15582.
294 Comprehensive Assessment of GPR68 Expression in Normal and Neoplastic Human Tissues Using a Novel Rabbit Monoclonal Antibody.Int J Mol Sci. 2019 Oct 23;20(21):5261. doi: 10.3390/ijms20215261.
295 The transcriptional co-activator NCOA6 promotes estrogen-induced GREB1 transcription by recruiting ER and enhancing enhancer-promoter interactions.J Biol Chem. 2019 Dec 20;294(51):19667-19682. doi: 10.1074/jbc.RA119.010704. Epub 2019 Nov 19.
296 SUMO-1 Promotes Ishikawa Cell Proliferation and Apoptosis in Endometrial Cancer by Increasing Sumoylation of Histone H4.Int J Gynecol Cancer. 2015 Oct;25(8):1364-8. doi: 10.1097/IGC.0000000000000501.
297 Medroxyprogesterone acetate causes the alterations of endoplasmic reticulum related mRNAs and lncRNAs in endometrial cancer cells.BMC Med Genomics. 2019 Nov 12;12(1):163. doi: 10.1186/s12920-019-0601-9.
298 X chromosome-linked long noncoding RNA lnc-XLEC1 regulates c-Myc-dependent cell growth by collaborating with MBP-1 in endometrial cancer.Int J Cancer. 2019 Aug 15;145(4):927-940. doi: 10.1002/ijc.32166. Epub 2019 Feb 23.
299 Identification of key pathways and genes in endometrial cancer using bioinformatics analyses.Oncol Lett. 2019 Jan;17(1):897-906. doi: 10.3892/ol.2018.9667. Epub 2018 Nov 5.
300 Cumulative evidence for relationships between multiple variants of HNF1B and the risk of prostate and endometrial cancers.BMC Med Genet. 2018 Jul 27;19(1):128. doi: 10.1186/s12881-018-0640-7.
301 Overexpression of HOMER2 predicts better outcome in low-grade endometrioid endometrial adenocarcinoma.Pathology. 2018 Aug;50(5):499-503. doi: 10.1016/j.pathol.2018.03.004. Epub 2018 Jun 8.
302 miR-10b Inhibits Apoptosis and Promotes Proliferation and Invasion of Endometrial Cancer Cells via Targeting HOXB3.Cancer Biother Radiopharm. 2016 Aug;31(6):225-31. doi: 10.1089/cbr.2016.1998.
303 HOXB9 promotes endometrial cancer progression by targeting E2F3.Cell Death Dis. 2018 May 1;9(5):509. doi: 10.1038/s41419-018-0556-3.
304 A functional polymorphism in the promoter of the progesterone receptor gene associated with endometrial cancer risk.Proc Natl Acad Sci U S A. 2002 Sep 17;99(19):12263-8. doi: 10.1073/pnas.192172299. Epub 2002 Sep 6.
305 Methylation status of KLF4 and HS3ST2 genes as predictors of endometrial cancer and hyperplastic endometrial lesions.Int J Mol Med. 2018 Dec;42(6):3318-3328. doi: 10.3892/ijmm.2018.3872. Epub 2018 Sep 12.
306 Expression patterns of hyaluronan, hyaluronan synthases and hyaluronidases indicate a role for hyaluronan in the progression of endometrial cancer.Gynecol Oncol. 2005 Aug;98(2):193-202. doi: 10.1016/j.ygyno.2005.02.031.
307 RNA-seq Reveals the Overexpression of IGSF9 in Endometrial Cancer.J Oncol. 2018 Feb 14;2018:2439527. doi: 10.1155/2018/2439527. eCollection 2018.
308 Dysregulated microRNAs and their predicted targets associated with endometrioid endometrial adenocarcinoma in Hong Kong women.Int J Cancer. 2009 Mar 15;124(6):1358-65. doi: 10.1002/ijc.24071.
309 Jupiter microtubule-associated homolog 1 (JPT1): A predictive and pharmacodynamic biomarker of metformin response in endometrial cancers.Cancer Med. 2020 Feb;9(3):1092-1103. doi: 10.1002/cam4.2729. Epub 2019 Dec 6.
310 TRIB3 suppresses proliferation and invasion and promotes apoptosis of endometrial cancer cells by regulating the AKT signaling pathway.Onco Targets Ther. 2019 Mar 27;12:2235-2245. doi: 10.2147/OTT.S189001. eCollection 2019.
311 Macrophage ER promoted invasion of endometrial cancer cell by mTOR/KIF5B-mediated epithelial to mesenchymal transition.Immunol Cell Biol. 2019 Jul;97(6):563-576. doi: 10.1111/imcb.12245. Epub 2019 Mar 14.
312 Dysregulation of Krppel-like factor 12 in the development of endometrial cancer.Gynecol Oncol. 2019 Jan;152(1):177-184. doi: 10.1016/j.ygyno.2018.10.028. Epub 2018 Oct 25.
313 Germline PTEN, SDHB-D, and KLLN alterations in endometrial cancer patients with Cowden and Cowden-like syndromes: an international, multicenter, prospective study.Cancer. 2015 Mar 1;121(5):688-96. doi: 10.1002/cncr.29106. Epub 2014 Nov 5.
314 LAT1 is a putative therapeutic target in endometrioid endometrial carcinoma.Int J Cancer. 2016 Dec 1;139(11):2529-39. doi: 10.1002/ijc.30371. Epub 2016 Aug 16.
315 miR?15 promotes epithelial to mesenchymal transition and proliferation by regulating LEFTY2 in endometrial cancer.Int J Mol Med. 2018 Sep;42(3):1229-1236. doi: 10.3892/ijmm.2018.3703. Epub 2018 May 22.
316 Galectin-7 is elevated in endometrioid (type I) endometrial cancer and promotes cell migration.Oncol Lett. 2018 Oct;16(4):4721-4728. doi: 10.3892/ol.2018.9193. Epub 2018 Jul 23.
317 Loss of Hugl-1 expression associates with lymph node metastasis in endometrial cancer.Oncol Res. 2007;16(9):431-5. doi: 10.3727/000000007783980855.
318 LRG1 is an independent prognostic factor for endometrial carcinoma.Tumour Biol. 2014 Jul;35(7):7125-33. doi: 10.1007/s13277-014-1953-6. Epub 2014 Apr 24.
319 Induction of the LRP16 gene by estrogen promotes the invasive growth of Ishikawa human endometrial cancer cells through the downregulation of E-cadherin.Cell Res. 2007 Oct;17(10):869-80. doi: 10.1038/cr.2007.79.
320 The feasibility of detecting endometrial and ovarian cancer using DNA methylation biomarkers in cervical scrapings.J Gynecol Oncol. 2018 Jan;29(1):e17. doi: 10.3802/jgo.2018.29.e17.
321 CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer.J Clin Pathol. 2014 Dec;67(12):1067-71. doi: 10.1136/jclinpath-2014-202616. Epub 2014 Oct 3.
322 SOX17 is a tumor suppressor in endometrial cancer.Oncotarget. 2016 Nov 15;7(46):76036-76046. doi: 10.18632/oncotarget.12582.
323 Functional and clinicopathological analysis of loss of MKK4 expression in endometrial cancer.Oncology. 2010;79(3-4):238-46. doi: 10.1159/000322644. Epub 2011 Mar 3.
324 Effect of Total Laparoscopic Hysterectomy vs Total Abdominal Hysterectomy on Disease-Free Survival Among Women With Stage I Endometrial Cancer: A Randomized Clinical Trial.JAMA. 2017 Mar 28;317(12):1224-1233. doi: 10.1001/jama.2017.2068.
325 miR-27b-3p/MARCH7 regulates invasion and metastasis of endometrial cancer cells through Snail-mediated pathway.Acta Biochim Biophys Sin (Shanghai). 2019 May 23;51(5):492-500. doi: 10.1093/abbs/gmz030.
326 Genotype misclassification in genetic association studies of the rs1042522 TP53 (Arg72Pro) polymorphism: a systematic review of studies of breast, lung, colorectal, ovarian, and endometrial cancer.Am J Epidemiol. 2013 Jun 15;177(12):1317-25. doi: 10.1093/aje/kws394. Epub 2013 May 31.
327 MAX Mutations in Endometrial Cancer: Clinicopathologic Associations and Recurrent MAX p.His28Arg Functional Characterization.J Natl Cancer Inst. 2018 May 1;110(5):517-526. doi: 10.1093/jnci/djx238.
328 Loss of MDC1 in Endometrial Carcinoma Is Associated With Loss of MRN Complex and MMR Deficiency.Anticancer Res. 2019 Dec;39(12):6547-6553. doi: 10.21873/anticanres.13870.
329 MDH2 Stimulated by Estrogen-GPR30 Pathway Down-Regulated PTEN Expression Promoting the Proliferation and Invasion of Cells in Endometrial Cancer.Transl Oncol. 2017 Apr;10(2):203-210. doi: 10.1016/j.tranon.2017.01.009. Epub 2017 Feb 9.
330 m(6)A mRNA methylation regulates AKT activity to promote the proliferation and tumorigenicity of endometrial cancer.Nat Cell Biol. 2018 Sep;20(9):1074-1083. doi: 10.1038/s41556-018-0174-4. Epub 2018 Aug 27.
331 Aquaporin-1 plays a crucial role in estrogen-induced tubulogenesis of vascular endothelial cells.J Clin Endocrinol Metab. 2013 Apr;98(4):E672-82. doi: 10.1210/jc.2012-4081. Epub 2013 Feb 28.
332 MLH3 mutation in endometrial cancer.Cancer Res. 2006 Aug 1;66(15):7502-8. doi: 10.1158/0008-5472.CAN-06-0248.
333 The MRPS18-2 protein levels correlate with prostate tumor progression and it induces CXCR4-dependent migration of cancer cells.Sci Rep. 2018 Feb 2;8(1):2268. doi: 10.1038/s41598-018-20765-8.
334 A monoclonal antibody (MSN-1) against a newly established uterine endometrial cancer cell line (SNG-II) and its application to immunohistochemistry and flow cytometry.Am J Obstet Gynecol. 1989 Oct;161(4):1079-86. doi: 10.1016/0002-9378(89)90787-4.
335 Epigenetic alteration of the metallothionein 1E gene in human endometrial carcinomas.Tumour Biol. 2009;30(2):93-9. doi: 10.1159/000218032. Epub 2009 May 6.
336 Estrogen receptor transcript variants associate with oncogene expression in endometrial cancer.Int J Mol Med. 2012 Jun;29(6):1127-36. doi: 10.3892/ijmm.2012.929. Epub 2012 Feb 28.
337 DNA methylation promotes paired box 2 expression via myeloid zinc finger 1 in endometrial cancer.Oncotarget. 2016 Dec 20;7(51):84785-84797. doi: 10.18632/oncotarget.12626.
338 Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.Proc Natl Acad Sci U S A. 2009 May 26;106(21):8677-82. doi: 10.1073/pnas.0903632106. Epub 2009 May 13.
339 Steroid Receptor Coactivator-2 Controls the Pentose Phosphate Pathway through RPIA in Human Endometrial Cancer Cells.Sci Rep. 2018 Sep 3;8(1):13134. doi: 10.1038/s41598-018-31372-y.
340 Neural precursor cell-expressed developmentally down-regulated 4-like: a new biomarker in the pathophysiology of endometrial cancer.J Int Med Res. 2018 Sep;46(9):3709-3716. doi: 10.1177/0300060518777944. Epub 2018 Jul 12.
341 Prognostic role of NF-YA splicing isoforms and Lamin A status in low grade endometrial cancer.Oncotarget. 2017 Jan 31;8(5):7935-7945. doi: 10.18632/oncotarget.13854.
342 Inflammasome as a Key Pathogenic Mechanism in Endometriosis.Curr Drug Targets. 2017;18(9):997-1002. doi: 10.2174/1389450117666160709013850.
343 MiR-29a-5p inhibits proliferation and invasion and induces apoptosis in endometrial carcinoma via targeting TPX2.Cell Cycle. 2018;17(10):1268-1278. doi: 10.1080/15384101.2018.1475829. Epub 2018 Jul 23.
344 Long noncoding RNA NR2F1-AS1 enhances the malignant properties of osteosarcoma by increasing forkhead box A1 expression via sponging of microRNA-483-3p.Aging (Albany NY). 2019 Dec 4;11(23):11609-11623. doi: 10.18632/aging.102563. Epub 2019 Dec 4.
345 New target genes in endometrial tumors show a role for the estrogen-receptor pathway in microsatellite-unstable cancers.Hum Mutat. 2014 Dec;35(12):1514-23. doi: 10.1002/humu.22700.
346 miR-34a, miR-424 and miR-513 inhibit MMSET expression to repress endometrial cancer cell invasion and sphere formation.Oncotarget. 2018 May 1;9(33):23253-23263. doi: 10.18632/oncotarget.25298. eCollection 2018 May 1.
347 Select human cancer mutants of NRMT1 alter its catalytic activity and decrease N-terminal trimethylation.Protein Sci. 2017 Aug;26(8):1639-1652. doi: 10.1002/pro.3202. Epub 2017 Jun 11.
348 OTU Domain-containing ubiquitin aldehyde-binding protein 1 (OTUB1) deubiquitinates estrogen receptor (ER) alpha and affects ERalpha transcriptional activity.J Biol Chem. 2009 Jun 12;284(24):16135-16145. doi: 10.1074/jbc.M109.007484. Epub 2009 Apr 21.
349 The Roles of Glycodelin in Cancer Development and Progression.Front Immunol. 2017 Nov 29;8:1685. doi: 10.3389/fimmu.2017.01685. eCollection 2017.
350 Membrane progesterone receptors and have potential as prognostic biomarkers of endometrial cancer.J Steroid Biochem Mol Biol. 2018 Apr;178:303-311. doi: 10.1016/j.jsbmb.2018.01.011. Epub 2018 Jan 17.
351 PAX2 in endometrial carcinogenesis and in differential diagnosis of endometrial hyperplasia: A systematic review and meta-analysis of diagnostic accuracy.Acta Obstet Gynecol Scand. 2019 Mar;98(3):287-299. doi: 10.1111/aogs.13512. Epub 2019 Jan 8.
352 Endoplasmic reticulum stress-mediated membrane expression of CRT/ERp57 induces immunogenic apoptosis in drug-resistant endometrial cancer cells.Oncotarget. 2017 May 8;8(35):58754-58764. doi: 10.18632/oncotarget.17678. eCollection 2017 Aug 29.
353 PELP1/MNAR suppression inhibits proliferation and metastasis of endometrial carcinoma cells.Oncol Rep. 2012 Dec;28(6):2035-42. doi: 10.3892/or.2012.2038. Epub 2012 Sep 17.
354 A First-in-Human Phase 1 Study of LY3023414, an Oral PI3K/mTOR Dual Inhibitor, in Patients with Advanced Cancer.Clin Cancer Res. 2018 Jul 15;24(14):3253-3262. doi: 10.1158/1078-0432.CCR-17-3421. Epub 2018 Apr 10.
355 Piwil1 causes epigenetic alteration of PTEN gene via upregulation of DNA methyltransferase in type I endometrial cancer.Biochem Biophys Res Commun. 2015 Aug 7;463(4):876-80. doi: 10.1016/j.bbrc.2015.06.028. Epub 2015 Jun 6.
356 Stem-cell protein Piwil2 is widely expressed in tumors and inhibits apoptosis through activation of Stat3/Bcl-XL pathway.Hum Mol Genet. 2006 Jan 15;15(2):201-11. doi: 10.1093/hmg/ddi430. Epub 2005 Dec 23.
357 Progesterone and 1,25-dihydroxyvitamin D? inhibit endometrial cancer cell growth by upregulating semaphorin 3B and semaphorin 3F. Mol Cancer Res. 2011 Nov;9(11):1479-92. doi: 10.1158/1541-7786.MCR-11-0213. Epub 2011 Sep 20.
358 Genetic and genomic basis of the mismatch repair system involved in Lynch syndrome.Int J Clin Oncol. 2019 Sep;24(9):999-1011. doi: 10.1007/s10147-019-01494-y. Epub 2019 Jul 4.
359 The influence of hormone therapy with drospirenone-estradiol on endometrioid type endometrial cancer patients.J Gynecol Oncol. 2018 Sep;29(5):e72. doi: 10.3802/jgo.2018.29.e72. Epub 2018 May 4.
360 Genetics of endometrial cancer.Fam Cancer. 2014 Sep;13(3):499-505. doi: 10.1007/s10689-014-9722-7.
361 Clinical outcomes of patients with POLE mutated endometrioid endometrial cancer.Gynecol Oncol. 2020 Jan;156(1):194-202. doi: 10.1016/j.ygyno.2019.10.028. Epub 2019 Nov 19.
362 Expression of hPOT1 in HeLa cells and the probability of gene variation of hpot1 Exon14 in endometrial cancer are much higher than in other cancers.Asian Pac J Cancer Prev. 2012;13(11):5659-63. doi: 10.7314/apjcp.2012.13.11.5659.
363 Genetic polymorphism of the plasminogen activator inhibitor-1 is associated with an increased risk of endometrial cancer.J Surg Oncol. 2011 Dec;104(7):755-9. doi: 10.1002/jso.22035. Epub 2011 Jul 14.
364 Expression of the retinoblastoma-related gene Rb2/p130 correlates with clinical outcome in endometrial cancer.J Clin Oncol. 1998 Mar;16(3):1085-93. doi: 10.1200/JCO.1998.16.3.1085.
365 Inhibition of PSMD4 blocks the tumorigenesis of hepatocellular carcinoma.Gene. 2019 Jun 20;702:66-74. doi: 10.1016/j.gene.2019.03.063. Epub 2019 Mar 28.
366 Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REG.Cancer Lett. 2015 May 1;360(2):269-79. doi: 10.1016/j.canlet.2015.02.028. Epub 2015 Feb 16.
367 Downregulation of PTPN18 can inhibit proliferation and metastasis and promote apoptosis of endometrial cancer.Clin Exp Pharmacol Physiol. 2019 Aug;46(8):734-742. doi: 10.1111/1440-1681.13098. Epub 2019 May 30.
368 Genetic overlap between endometriosis and endometrial cancer: evidence from cross-disease genetic correlation and GWAS meta-analyses.Cancer Med. 2018 May;7(5):1978-1987. doi: 10.1002/cam4.1445. Epub 2018 Apr 2.
369 Patterns of Failures and Clinical Outcome of Patients with Early-Stage, High-Risk, Node-Negative Endometrial Cancer Treated with Surgery Followed by Adjuvant Platinum-Based Chemotherapy and Vaginal Brachytherapy.Oncology. 2019;96(5):235-241. doi: 10.1159/000492430. Epub 2019 Mar 22.
370 Expression of Rb2/p130 in breast and endometrial cancer: correlations with hormone receptor status.Br J Cancer. 2001 Aug 17;85(4):546-51. doi: 10.1054/bjoc.2001.1923.
371 Elevated expression of RIT1 correlates with poor prognosis in endometrial cancer.Int J Clin Exp Pathol. 2015 Sep 1;8(9):10315-24. eCollection 2015.
372 Meta-dimensional data integration identifies critical pathways for susceptibility, tumorigenesis and progression of endometrial cancer.Oncotarget. 2016 Aug 23;7(34):55249-55263. doi: 10.18632/oncotarget.10509.
373 Pir2/Rnf144b is a potential endometrial cancer biomarker that promotes cell proliferation. Cell Death Dis. 2018 May 1;9(5):504. doi: 10.1038/s41419-018-0521-1.
374 Association of Polymerase e-Mutated and Microsatellite-Instable Endometrial Cancers With Neoantigen Load, Number of Tumor-Infiltrating Lymphocytes, and Expression of PD-1 and PD-L1.JAMA Oncol. 2015 Dec;1(9):1319-23. doi: 10.1001/jamaoncol.2015.2151.
375 Frequent mutations in the RPL22 gene and its clinical and functional implications.Gynecol Oncol. 2013 Mar;128(3):470-4. doi: 10.1016/j.ygyno.2012.10.026. Epub 2012 Nov 2.
376 Expression of Semaphorin 3B (SEMA3B) in Various Grades of Endometrial Cancer.Med Sci Monit. 2019 Jun 20;25:4569-4574. doi: 10.12659/MSM.916762.
377 Assessment of the Usefulness of the SEMA5A Concentration Profile Changes as a Molecular Marker in Endometrial Cancer.Curr Pharm Biotechnol. 2020;21(1):45-51. doi: 10.2174/1389201020666190911113611.
378 Interactions between microRNA-200 family and Sestrin proteins in endometrial cancer cell lines and their significance to anoikis.Mol Cell Biochem. 2019 Sep;459(1-2):21-34. doi: 10.1007/s11010-019-03547-2. Epub 2019 May 9.
379 Association of body mass index with ER, PR and 14-3-3 expression in tumor and stroma of type I and type II endometrial carcinoma.Oncotarget. 2017 Jun 27;8(26):42548-42559. doi: 10.18632/oncotarget.17209.
380 CYP1A1, SULT1A1, and SULT1E1 polymorphisms are risk factors for endometrial cancer susceptibility.Cancer. 2008 May 1;112(9):1964-73. doi: 10.1002/cncr.23392.
381 Curcumin exhibits anti-tumor effect and attenuates cellular migration via Slit-2 mediated down-regulation of SDF-1 and CXCR4 in endometrial adenocarcinoma cells.J Nutr Biochem. 2017 Jun;44:60-70. doi: 10.1016/j.jnutbio.2016.12.021. Epub 2017 Mar 16.
382 Para-aortic Lymph Node Invasion in High-risk Endometrial Cancer: Performance of (18)FDG PET-CT.Anticancer Res. 2019 Feb;39(2):619-625. doi: 10.21873/anticanres.13155.
383 SOX11 hypermethylation as a tumor biomarker in endometrial cancer.Biochimie. 2019 Jul;162:8-14. doi: 10.1016/j.biochi.2019.03.019. Epub 2019 Mar 29.
384 Overexpression of microRNA-194 suppresses the epithelial-mesenchymal transition in targeting stem cell transcription factor Sox3 in endometrial carcinoma stem cells.Tumour Biol. 2017 Jun;39(6):1010428317706217. doi: 10.1177/1010428317706217.
385 UBE2S mediates tumor progression via SOX6/-Catenin signaling in endometrial cancer.Int J Biochem Cell Biol. 2019 Apr;109:17-22. doi: 10.1016/j.biocel.2019.01.014. Epub 2019 Jan 25.
386 SPOCK2 Affects the Biological Behavior of Endometrial Cancer Cells by Regulation of MT1-MMP and MMP2.Reprod Sci. 2019 Mar 4:1933719119834341. doi: 10.1177/1933719119834341. Online ahead of print.
387 F-Spondin Is the Signal by Which 2-Methoxyestradiol Induces Apoptosis in the Endometrial Cancer Cell Line Ishikawa.Int J Mol Sci. 2019 Aug 7;20(16):3850. doi: 10.3390/ijms20163850.
388 Uterine function in the mouse requires speckle-type poz protein.Biol Reprod. 2018 Jun 1;98(6):856-869. doi: 10.1093/biolre/ioy060.
389 Association between the expression of secreted phosphoprotein - related genes and prognosis of human cancer.BMC Cancer. 2019 Dec 18;19(1):1230. doi: 10.1186/s12885-019-6441-3.
390 Associations between a single nucleotide polymorphism of stress-induced phosphoprotein 1 and endometriosis/adenomyosis.Taiwan J Obstet Gynecol. 2018 Apr;57(2):270-275. doi: 10.1016/j.tjog.2018.03.001.
391 Nomegestrol Acetate Suppresses Human Endometrial Cancer RL95-2 Cells Proliferation In Vitro and In Vivo Possibly Related to Upregulating Expression of SUFU and Wnt7a.Int J Mol Sci. 2017 Jun 22;18(7):1337. doi: 10.3390/ijms18071337.
392 Downregulation of endometrial mesenchymal marker SUSD2 causes cell senescence and cell death in endometrial carcinoma cells.PLoS One. 2017 Aug 25;12(8):e0183681. doi: 10.1371/journal.pone.0183681. eCollection 2017.
393 TESTIN was commonly hypermethylated and involved in the epithelial-mesenchymal transition of endometrial cancer.APMIS. 2015 May;123(5):394-400. doi: 10.1111/apm.12361. Epub 2015 Feb 27.
394 Differential expression of ten-eleven translocation genes in endometrial cancers.Tumour Biol. 2017 Mar;39(3):1010428317695017. doi: 10.1177/1010428317695017.
395 Decreased expression of TFAP2B in endometrial cancer predicts poor prognosis: A study based on TCGA data.Gynecol Oncol. 2018 Jun;149(3):592-597. doi: 10.1016/j.ygyno.2018.03.057. Epub 2018 Mar 28.
396 Nucleophosmin/B23 is a negative regulator of estrogen receptor expression via AP2 in endometrial cancer cells.Oncotarget. 2016 Sep 13;7(37):60038-60052. doi: 10.18632/oncotarget.11048.
397 Thrombospondin-1 and -2 messenger RNA expression in normal and neoplastic endometrial tissues: correlation with angiogenesis and prognosis.Int J Oncol. 2001 Aug;19(2):305-10. doi: 10.3892/ijo.19.2.305.
398 Imbalanced expression of TAN-1 and human Notch4 in endometrial cancers.Int J Oncol. 2000 Dec;17(6):1131-9. doi: 10.3892/ijo.17.6.1131.
399 Association of TNFAIP8 gene polymorphisms with endometrial cancer in northern Chinese women.Cancer Cell Int. 2019 Apr 23;19:105. doi: 10.1186/s12935-019-0827-9. eCollection 2019.
400 Identification of DNA methylation associated gene signatures in endometrial cancer via integrated analysis of DNA methylation and gene expression systematically.J Gynecol Oncol. 2017 Nov;28(6):e83. doi: 10.3802/jgo.2017.28.e83.
401 Expression of TRA2B in endometrial carcinoma and its regulatory roles in endometrial carcinoma cells.Oncol Lett. 2019 Sep;18(3):2455-2463. doi: 10.3892/ol.2019.10553. Epub 2019 Jul 3.
402 RETRACTED: TRAF4 promotes endometrial cancer cell growth and migration by activation of PI3K/AKT/Oct4 signaling.Exp Mol Pathol. 2019 Jun;108:9-16. doi: 10.1016/j.yexmp.2019.03.003. Epub 2019 Mar 7.
403 Effects of Intermediate-Conductance Ca(2+)-Activated K(+) Channels on Human Endometrial Carcinoma Cells.Cell Biochem Biophys. 2015 Jun;72(2):515-25. doi: 10.1007/s12013-014-0497-0.
404 Identification of TRIM22 as a progesterone-responsive gene in Ishikawa endometrial cancer cells.J Steroid Biochem Mol Biol. 2015 Nov;154:217-25. doi: 10.1016/j.jsbmb.2015.08.024. Epub 2015 Aug 24.
405 High TRIM44 expression in endometrial carcinoma is associated with a poorer patient outcome.Pathol Res Pract. 2018 May;214(5):727-731. doi: 10.1016/j.prp.2018.03.007. Epub 2018 Mar 6.
406 Meta-analysis of genome-wide association studies identifies common susceptibility polymorphisms for colorectal and endometrial cancer near SH2B3 and TSHZ1.Sci Rep. 2015 Dec 1;5:17369. doi: 10.1038/srep17369.
407 Expression of tumor suppressor genes related to the cell cycle in endometrial cancer patients.Adv Med Sci. 2016 Sep;61(2):317-324. doi: 10.1016/j.advms.2016.04.001. Epub 2016 Apr 13.
408 Sperm protein 17 is highly expressed in endometrial and cervical cancers.BMC Cancer. 2010 Aug 16;10:429. doi: 10.1186/1471-2407-10-429.
409 LVSI positive and NX in early endometrial cancer: Surgical restaging (and no further treatment if N0), or adjuvant ERT?.Gynecol Oncol. 2020 Jan;156(1):243-250. doi: 10.1016/j.ygyno.2019.09.016. Epub 2019 Nov 5.
410 Expression of the Receptor for Hyaluronic Acid-Mediated Motility (RHAMM) in Endometrial Cancer is Associated With Adverse Histologic Parameters and Tumor Progression.Appl Immunohistochem Mol Morphol. 2020 Jul;28(6):453-459. doi: 10.1097/PAI.0000000000000763.
411 Hypoxia is involved in the reduction of HtrA3 in patients with endometrial hyperplasia and cancer.Biochem Biophys Res Commun. 2018 Sep 18;503(4):2918-2923. doi: 10.1016/j.bbrc.2018.08.070. Epub 2018 Aug 20.
412 Germline mutation of MSH6 as the cause of hereditary nonpolyposis colorectal cancer. Nat Genet. 1997 Nov;17(3):271-2. doi: 10.1038/ng1197-271.
413 High expression of MUC20 drives tumorigenesis and predicts poor survival in endometrial cancer.J Cell Biochem. 2019 Jul;120(7):11859-11866. doi: 10.1002/jcb.28466. Epub 2019 Feb 19.
414 Abnormal Expression of PICT-1 and Its Codon 389 Polymorphism Is a Risk Factor for Human Endometrial Cancer.Oncology. 2018;95(1):43-51. doi: 10.1159/000487189. Epub 2018 Apr 4.
415 PGK1 facilities cisplatin chemoresistance by triggering HSP90/ERK pathway mediated DNA repair and methylation in endometrial endometrioid adenocarcinoma.Mol Med. 2019 Mar 29;25(1):11. doi: 10.1186/s10020-019-0079-0.
416 Alternative splicing of VEGFA is regulated by RBM10 in endometrial cancer.Kaohsiung J Med Sci. 2020 Jan;36(1):13-19. doi: 10.1002/kjm2.12127. Epub 2019 Oct 6.
417 Cellular retinol binding protein-1 expression in endometrial hyperplasia and carcinoma: diagnostic and possible therapeutic implications.Mod Pathol. 2006 Jun;19(6):797-803. doi: 10.1038/modpathol.3800586.
418 Investigation of resistin 420 and 62 gene polymorphism in patients with endometrial cancer.Taiwan J Obstet Gynecol. 2019 Jan;58(1):164-167. doi: 10.1016/j.tjog.2018.11.030.