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Ponatinib FDA Label
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Pathologic significance of a novel oncoprotein in thyroid cancer progression.Head Neck. 2017 Dec;39(12):2459-2469. doi: 10.1002/hed.24913. Epub 2017 Oct 11.
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Function of HSP90 and p23 in the telomerase complex of thyroid tumors.Pathol Res Pract. 2003;199(9):573-9. doi: 10.1078/0344-0338-00464.
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nc886, a non-coding RNA and suppressor of PKR, exerts an oncogenic function in thyroid cancer.Oncotarget. 2016 Nov 15;7(46):75000-75012. doi: 10.18632/oncotarget.11852.
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Autotaxin is an inflammatory mediator and therapeutic target in thyroid cancer.Endocr Relat Cancer. 2015 Aug;22(4):593-607. doi: 10.1530/ERC-15-0045. Epub 2015 Jun 2.
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Upregulation of Tyrosine Kinase FYN in Human Thyroid Carcinoma: Role in Modulating Tumor Cell Proliferation, Invasion, and Migration.Cancer Biother Radiopharm. 2017 Nov;32(9):320-326. doi: 10.1089/cbr.2017.2218.
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Inhibitory Effects of Antagonists of Growth Hormone-Releasing Hormone (GHRH) in Thyroid Cancer.Horm Cancer. 2017 Dec;8(5-6):314-324. doi: 10.1007/s12672-017-0307-4. Epub 2017 Sep 18.
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Ginsenoside improves papillary thyroid cancer cell malignancies partially through upregulating connexin 31.Kaohsiung J Med Sci. 2018 Jun;34(6):313-320. doi: 10.1016/j.kjms.2017.12.006. Epub 2018 Jan 17.
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Mitochondrial metabolism is inhibited by the HIF1-MYC-PGC-1 axis in BRAF V600E thyroid cancer.FEBS J. 2019 Apr;286(7):1420-1436. doi: 10.1111/febs.14786. Epub 2019 Mar 5.
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Genetic Alterations in Hungarian Patients with Papillary Thyroid Cancer.Pathol Oncol Res. 2016 Jan;22(1):27-33. doi: 10.1007/s12253-015-9969-9. Epub 2015 Aug 11.
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KSR1 is coordinately regulated with Notch signaling and oxidative phosphorylation in thyroid cancer.J Mol Endocrinol. 2015 Apr;54(2):115-24. doi: 10.1530/JME-14-0270. Epub 2015 Jan 21.
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Silencing of LIM and SH3 Protein 1 (LASP-1) Inhibits Thyroid Cancer Cell Proliferation and Invasion.Oncol Res. 2017 Jul 5;25(6):879-886. doi: 10.3727/096504016X14785415155643. Epub 2016 Nov 17.
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Synergistic effects of BET and MEK inhibitors promote regression of anaplastic thyroid tumors.Oncotarget. 2018 Oct 23;9(83):35408-35421. doi: 10.18632/oncotarget.26253. eCollection 2018 Oct 23.
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Functional analysis of a novel, thyroglobulin-embedded microRNA gene deregulated in papillary thyroid carcinoma.Sci Rep. 2017 Aug 30;7(1):9942. doi: 10.1038/s41598-017-10318-w.
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Promotion of tumor progression and cancer stemness by MUC15 in thyroid cancer via the GPCR/ERK and integrin-FAK signaling pathways.Oncogenesis. 2018 Nov 12;7(11):85. doi: 10.1038/s41389-018-0094-y.
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TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease.J Clin Endocrinol Metab. 2017 Jun 1;102(6):1898-1907. doi: 10.1210/jc.2016-2785.
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MicroRNA-146a targets PRKCE to modulate papillary thyroid tumor development.Int J Cancer. 2014 Jan 15;134(2):257-67. doi: 10.1002/ijc.28141. Epub 2013 Sep 18.
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Expression of the cAMP binding protein EPAC1 in thyroid tumors and growth regulation of thyroid cells and thyroid carcinoma cells by EPAC proteins.Horm Metab Res. 2015 Mar;47(3):200-8. doi: 10.1055/s-0034-1390484. Epub 2014 Nov 5.
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Sphingosine 1-phosphate attenuates MMP2 and MMP9 in human anaplastic thyroid cancer C643 cells: Importance of S1P2.PLoS One. 2018 May 7;13(5):e0196992. doi: 10.1371/journal.pone.0196992. eCollection 2018.
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New Treatment of Medullary and Papillary Human Thyroid Cancer: Biological Effects of Hyaluronic Acid Hydrogel Loaded With Quercetin Alone or in Combination to an Inhibitor of Aurora Kinase.J Cell Physiol. 2016 Aug;231(8):1784-95. doi: 10.1002/jcp.25283. Epub 2016 Feb 2.
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LncRNA-SLC6A9-5:2: A potent sensitizer in 131I-resistant papillary thyroid carcinoma with PARP-1 induction.Oncotarget. 2017 Apr 4;8(14):22954-22967. doi: 10.18632/oncotarget.14578.
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Stomatin-like protein 2 overexpression in papillary thyroid carcinoma is significantly associated with high-risk clinicopathological parameters and BRAFV600E mutation.APMIS. 2016 Apr;124(4):271-7. doi: 10.1111/apm.12505. Epub 2016 Jan 11.
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Long noncoding RNA H19 competitively binds miR-17-5p to regulate YES1 expression in thyroid cancer.FEBS J. 2016 Jun;283(12):2326-39. doi: 10.1111/febs.13741. Epub 2016 May 12.
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The AMPK-activator AICAR in thyroid cancer: effects on CXCL8 secretion and on CXCL8-induced neoplastic cell migration.J Endocrinol Invest. 2018 Nov;41(11):1275-1282. doi: 10.1007/s40618-018-0862-8. Epub 2018 Mar 15.
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Neurotrophin Receptors TrkA, p75(NTR), and Sortilin Are Increased and Targetable in Thyroid Cancer.Am J Pathol. 2018 Jan;188(1):229-241. doi: 10.1016/j.ajpath.2017.09.008. Epub 2017 Oct 14.
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RAF-1 promotes survival of thyroid cancer cells harboring RET/PTC1 rearrangement independently of ERK activation.Mol Cell Endocrinol. 2015 Nov 5;415:64-75. doi: 10.1016/j.mce.2015.08.006. Epub 2015 Aug 8.
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DARC (Duffy) and BCAM (Lutheran) reduced expression in thyroid cancer.Blood Cells Mol Dis. 2013 Mar;50(3):161-5. doi: 10.1016/j.bcmd.2012.10.009. Epub 2012 Nov 17.
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BTG1 expression in thyroid carcinoma: diagnostic indicator and prognostic marker.Int J Oncol. 2014 Oct;45(4):1574-82. doi: 10.3892/ijo.2014.2543. Epub 2014 Jul 11.
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Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 and cyclin E2.Oncotarget. 2015 Oct 13;6(31):31780-91. doi: 10.18632/oncotarget.5566.
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Immunohistochemical cellular distribution of proteins related to M phase regulation in early proliferative lesions induced by tumor promotion in rat two-stage carcinogenesis models.Exp Toxicol Pathol. 2014 Jan;66(1):1-11. doi: 10.1016/j.etp.2013.07.001. Epub 2013 Jul 23.
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Contactin 1 as a potential biomarker promotes cell proliferation and invasion in thyroid cancer.Int J Clin Exp Pathol. 2015 Oct 1;8(10):12473-81. eCollection 2015.
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Influence of CYP3A4/5 and ABC transporter polymorphisms on lenvatinib plasma trough concentrations in Japanese patients with thyroid cancer. Sci Rep. 2019 Apr 1;9(1):5404.
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A phase II trial of doxorubicin and interferon alpha 2b in advanced, non-medullary thyroid cancer.Invest New Drugs. 2008 Apr;26(2):183-8. doi: 10.1007/s10637-007-9091-2. Epub 2007 Oct 2.
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Interplay between thyroid cancer cells and macrophages: effects on IL-32 mediated cell death and thyroid cancer cell migration.Cell Oncol (Dordr). 2019 Oct;42(5):691-703. doi: 10.1007/s13402-019-00457-9. Epub 2019 Jun 14.
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MiR-20a is upregulated in anaplastic thyroid cancer and targets LIMK1.PLoS One. 2014 May 23;9(5):e96103. doi: 10.1371/journal.pone.0096103. eCollection 2014.
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SIN1, a critical component of the mTOR-Rictor complex, is overexpressed and associated with AKT activation in medullary and aggressive papillary thyroid carcinomas.Surgery. 2014 Dec;156(6):1542-8; discussion 1548-9. doi: 10.1016/j.surg.2014.08.095. Epub 2014 Nov 11.
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Evaluation of thyroid cancer in Chinese females with breast cancer by vascular endothelial growth factor (VEGF), microvessel density, and contrast-enhanced ultrasound (CEUS).Tumour Biol. 2014 Jul;35(7):6521-9. doi: 10.1007/s13277-014-1868-2. Epub 2014 Apr 1.
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Identification of thyroid carcinoma related genes with mRMR and shortest path approaches.PLoS One. 2014 Apr 9;9(4):e94022. doi: 10.1371/journal.pone.0094022. eCollection 2014.
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Prostaglandin synthases influence thyroid follicular cell proliferation but not carcinogenesis in rats initiated with N-bis(2-hydroxypropyl)nitrosamine.Toxicol Sci. 2012 Jun;127(2):339-47. doi: 10.1093/toxsci/kfs097. Epub 2012 Mar 2.
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RAIN Is a Novel Enhancer-Associated lncRNA That Controls RUNX2 Expression and Promotes Breast and Thyroid Cancer.Mol Cancer Res. 2020 Jan;18(1):140-152. doi: 10.1158/1541-7786.MCR-19-0564. Epub 2019 Oct 17.
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Cancer-related genes transcriptionally induced by the fungicide penconazole.Toxicol In Vitro. 2014 Feb;28(1):125-30. doi: 10.1016/j.tiv.2013.06.006. Epub 2013 Jun 27.
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Cowden syndrome-associated germline succinate dehydrogenase complex subunit D (SDHD) variants cause PTEN-mediated down-regulation of autophagy in thyroid cancer cells.Hum Mol Genet. 2017 Apr 1;26(7):1365-1375. doi: 10.1093/hmg/ddx037.
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Inhibition of microRNA-875-5p promotes radioiodine uptake in poorly differentiated thyroid carcinoma cells by upregulating sodium-iodide symporter.J Endocrinol Invest. 2020 Apr;43(4):439-450. doi: 10.1007/s40618-019-01125-3. Epub 2019 Oct 14.
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Is transketolase like 1 a target for the treatment of differentiated thyroid carcinoma? A study on thyroid cancer cell lines.Invest New Drugs. 2009 Aug;27(4):297-303. doi: 10.1007/s10637-008-9174-8. Epub 2008 Sep 20.
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Evaluation of preclinical efficacy of everolimus and pasireotide in thyroid cancer cell lines and xenograft models.PLoS One. 2019 Feb 26;14(2):e0206309. doi: 10.1371/journal.pone.0206309. eCollection 2019.
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Transient Receptor Potential Canonical 1 (TRPC1) Channels as Regulators of Sphingolipid and VEGF Receptor Expression: IMPLICATIONS FOR THYROID CANCER CELL MIGRATION AND PROLIFERATION.J Biol Chem. 2015 Jun 26;290(26):16116-31. doi: 10.1074/jbc.M115.643668. Epub 2015 May 13.
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miR-217 inhibits proliferation, migration, and invasion via targeting AKT3 in thyroid cancer.Biomed Pharmacother. 2017 Nov;95:1718-1724. doi: 10.1016/j.biopha.2017.09.074. Epub 2017 Oct 6.
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Characterization of thyroid cancer driven by known and novel ALK fusions.Endocr Relat Cancer. 2019 Nov;26(11):803-814. doi: 10.1530/ERC-19-0325.
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Inhibition of BRD4 suppresses tumor growth and enhances iodine uptake in thyroid cancer. Biochem Biophys Res Commun. 2016 Jan 15;469(3):679-85. doi: 10.1016/j.bbrc.2015.12.008. Epub 2015 Dec 18.
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Overexpression of the mitotic spindle assembly checkpoint genes hBUB1, hBUBR1 and hMAD2 in thyroid carcinomas with aggressive nature.Anticancer Res. 2008 Jan-Feb;28(1A):139-44.
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Molecular markers for discrimination of benign and malignant follicular thyroid tumors.Tumour Biol. 2006;27(4):211-20. doi: 10.1159/000093056. Epub 2006 May 2.
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The loss of the CBX7 gene expression represents an adverse prognostic marker for survival of colon carcinoma patients.Eur J Cancer. 2010 Aug;46(12):2304-13. doi: 10.1016/j.ejca.2010.05.011. Epub 2010 Jun 9.
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The cholecystokinin2-receptor mediates calcitonin secretion, gene expression, and proliferation in the human medullary thyroid carcinoma cell line, TT.Regul Pept. 2004 Apr 15;118(1-2):111-7. doi: 10.1016/j.regpep.2003.11.007.
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The multifaceted anti-cancer effects of BRAF-inhibitors.Oncotarget. 2019 Nov 12;10(61):6623-6640. doi: 10.18632/oncotarget.27304. eCollection 2019 Nov 12.
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Long non-coding RNA NR2F1-AS1 promoted proliferation and migration yet suppressed apoptosis of thyroid cancer cells through regulating miRNA-338-3p/CCND1 axis.J Cell Mol Med. 2019 Sep;23(9):5907-5919. doi: 10.1111/jcmm.14386. Epub 2019 Jul 14.
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Distinct patterns of E-cadherin CpG island methylation in papillary, follicular, Hurthle's cell, and poorly differentiated human thyroid carcinoma.Cancer Res. 1998 May 15;58(10):2063-6.
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Cadherin-6 promotes EMT and cancer metastasis by restraining autophagy.Oncogene. 2017 Feb 2;36(5):667-677. doi: 10.1038/onc.2016.237. Epub 2016 Jul 4.
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Cellular distributions of molecules with altered expression specific to thyroid proliferative lesions developing in a rat thyroid carcinogenesis model.Cancer Sci. 2009 Apr;100(4):617-25. doi: 10.1111/j.1349-7006.2009.01094.x. Epub 2009 Feb 25.
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Cyclin-dependent kinase 5 modulates STAT3 and androgen receptor activation through phosphorylation of Ser on STAT3 in prostate cancer cells.Am J Physiol Endocrinol Metab. 2013 Oct 15;305(8):E975-86. doi: 10.1152/ajpendo.00615.2012. Epub 2013 Aug 13.
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P18 is a tumor suppressor gene involved in human medullary thyroid carcinoma and pheochromocytoma development.Int J Cancer. 2009 Jan 15;124(2):339-45. doi: 10.1002/ijc.23977.
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Induction of sodium iodide symporter gene and molecular characterisation of HNF3 beta/FoxA2, TTF-1 and C/EBP beta in thyroid carcinoma cells.Br J Cancer. 2008 Sep 2;99(5):781-8. doi: 10.1038/sj.bjc.6604544.
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Identification of Key Genes in Thyroid Cancer Microenvironment.Med Sci Monit. 2019 Dec 16;25:9602-9608. doi: 10.12659/MSM.918519.
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Multiple anti-tumor effects of Reparixin on thyroid cancer.Oncotarget. 2017 May 30;8(22):35946-35961. doi: 10.18632/oncotarget.16412.
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The expression and role of serum response factor in papillary carcinoma of the thyroid.Int J Oncol. 2009 Jul;35(1):49-55.
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CYP24A1 depletion facilitates the antitumor effect of vitamin D3 on thyroid cancer cells.Exp Ther Med. 2018 Oct;16(4):2821-2830. doi: 10.3892/etm.2018.6536. Epub 2018 Jul 27.
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Coexpression of EpCAM, CD44 variant isoforms and claudin-7 in anaplastic thyroid carcinoma.PLoS One. 2014 Apr 11;9(4):e94487. doi: 10.1371/journal.pone.0094487. eCollection 2014.
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Clinical utility of EZH1 mutations in the diagnosis of follicular-patterned thyroid tumors.Hum Pathol. 2018 Nov;81:9-17. doi: 10.1016/j.humpath.2018.04.018. Epub 2018 May 1.
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Selected single-nucleotide polymorphisms in FOXE1, SERPINA5, FTO, EVPL, TICAM1 and SCARB1 are associated with papillary and follicular thyroid cancer risk: replication study in a German population.Carcinogenesis. 2016 Jul;37(7):677-684. doi: 10.1093/carcin/bgw047. Epub 2016 Apr 28.
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Neovascular PSMA expression is a common feature in malignant neoplasms of the thyroid.Oncotarget. 2018 Jan 4;9(11):9867-9874. doi: 10.18632/oncotarget.23984. eCollection 2018 Feb 9.
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TGF-1 induces HMGA1 expression: The role of HMGA1 in thyroid cancer proliferation and invasion.Int J Oncol. 2017 May;50(5):1567-1578. doi: 10.3892/ijo.2017.3958. Epub 2017 Apr 7.
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HMGA2 Gene Expression in Fine-needle Aspiration Samples of Thyroid Nodules as a Marker for Preoperative Diagnosis of Thyroid Cancer.Appl Immunohistochem Mol Morphol. 2019 Jul;27(6):471-476. doi: 10.1097/PAI.0000000000000637.
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Genetic polymorphisms in IL1R1 and IL1R2 are associated with susceptibility to thyroid cancer in the Chinese Han population.J Gene Med. 2019 Jun;21(6):e3093. doi: 10.1002/jgm.3093. Epub 2019 May 27.
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Lysyl Oxidase Is a Key Player in BRAF/MAPK Pathway-Driven Thyroid Cancer Aggressiveness.Thyroid. 2019 Jan;29(1):79-92. doi: 10.1089/thy.2018.0424. Epub 2018 Dec 28.
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