General Information of Disease (ID: DISR1UCN)

Disease Name Colorectal neoplasm
Synonyms
large bowel tumour; tumour of large bowel; tumor of the large bowel; large bowel neoplasm; tumor of colorectum; large intestine tumor; neoplasm of the large bowel; neoplasm of colorectum; large intestine tumour; colorectal tumour; tumour of colorectum; colorectal neoplasm; large intestinal neoplasm; tumor of large bowel; large intestine neoplasm; colorectum neoplasm (disease); colorectum tumour; neoplasm of large bowel; colorectal tumor; tumour of the large bowel; colorectum tumor; colorectum neoplasm; large bowel tumor
Definition
A benign or malignant neoplasm that affects the colon or rectum. Representative examples of benign neoplasms include lipoma and leiomyoma. Representative examples of malignant neoplasms include carcinoma, lymphoma, and sarcoma. Colorectal adenomas always exhibit epithelial dysplasia and are considered premalignant neoplasms.
Disease Hierarchy
DISK0GUH: Intestinal neoplasm
DISTBY9Z: Tumour
DISKU8JE: Large intestine disorder
DISR1UCN: Colorectal neoplasm
Disease Identifiers
MONDO ID
MONDO_0005335
MESH ID
D015179
UMLS CUI
C0009404
MedGen ID
3171
HPO ID
HP:0100834
SNOMED CT ID
126837005

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 314 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCB1 TT3OT40 Limited Biomarker [1]
ACVR2A TTX2DRI Limited Genetic Variation [2]
ADK TTL732K Limited Altered Expression [3]
ALDH2 TTFLN4T Limited Genetic Variation [4]
AMACR TTLN1AP Limited Altered Expression [5]
CD24 TTCTYNP Limited Altered Expression [6]
CEACAM5 TTY6DTE Limited Biomarker [7]
CSF2 TTNYZG2 Limited Biomarker [8]
CYP1A2 TTS1DTU Limited Biomarker [9]
EPHA4 TTG84D3 Limited Altered Expression [10]
EPHB2 TTKPV6O Limited Posttranslational Modification [11]
FZD10 TTP1S2F Limited Altered Expression [12]
KCNK9 TTL4FMB Limited Genetic Variation [13]
KDR TTUTJGQ Limited Therapeutic [14]
LTC4S TTW7OTG Limited Genetic Variation [15]
MAP2K2 TT8H9GB Limited Biomarker [16]
MMP2 TTLM12X Limited Genetic Variation [17]
NME1 TTDY8JH Limited Biomarker [18]
NTN1 TT0AH4L Limited Altered Expression [19]
PDX1 TT8SGZK Limited Altered Expression [20]
PIK3CA TTEUNMR Limited Biomarker [21]
PTK7 TTXH2ZN Limited Altered Expression [22]
ROBO4 TT3S9TY Limited Biomarker [23]
SIK3 TTW6L4V Limited Biomarker [24]
SLC6A14 TTB6H2S Limited Altered Expression [25]
SUV39H1 TTUWQTK Limited Posttranslational Modification [26]
TCF7L2 TT80QAL Limited Genetic Variation [27]
TLR2 TTY7ZHS Limited Biomarker [28]
TLR4 TTISGCA Limited Biomarker [29]
TMEM97 TT9NXW4 Limited Biomarker [30]
TRPM7 TTFPVZO Limited Biomarker [31]
TXNRD1 TTR7UJ3 Limited Biomarker [32]
ACKR3 TTRQJTC Disputed Biomarker [29]
APC2 TTSMK36 Disputed Biomarker [33]
DHFR TTYZVDJ Disputed Biomarker [18]
GPNMB TT7315J Disputed Biomarker [33]
LY96 TT8S9AV Disputed Biomarker [29]
PRKD1 TTSLUMT Disputed Biomarker [33]
RRM2 TT1S4LJ Disputed Biomarker [18]
AKT2 TTH24WI moderate Genetic Variation [34]
AURKA TTPS3C0 moderate Biomarker [35]
ESR2 TTOM3J0 moderate Biomarker [36]
FAT1 TTGUJYV moderate Biomarker [37]
GREM1 TTOUZN5 moderate Altered Expression [38]
GUCY2C TTLDPRG moderate Altered Expression [39]
IGF2 TTE8WGO moderate Altered Expression [40]
MLH1 TTISG27 moderate Biomarker [41]
MSH2 TTCAWRT moderate Altered Expression [42]
NRAS TTW2R9X moderate Genetic Variation [43]
PTBP1 TTWMX0U moderate Biomarker [44]
PTGS2 TTVKILB moderate Biomarker [45]
SOD2 TT9O4C5 moderate Biomarker [46]
ABCC2 TTFLHJV Strong Biomarker [47]
ABCG2 TTIMJ02 Strong Altered Expression [48]
ACO2 TTMTF2P Strong Genetic Variation [49]
ADORA3 TTJFY5U Strong Altered Expression [50]
ALOX12 TT12ABZ Strong Genetic Variation [51]
ALOX15 TTN9T81 Strong Posttranslational Modification [52]
ATF3 TTCE793 Strong Altered Expression [53]
ATP7B TTOPO51 Strong Biomarker [54]
ATXN2 TTPQJ7P Strong Genetic Variation [55]
B2M TTY7FKA Strong Genetic Variation [43]
BAGE TTS5GLJ Strong Genetic Variation [56]
BBC3 TT7JUKC Strong Biomarker [57]
BCAT1 TTES57P Strong Biomarker [58]
BCL2 TTFOUV4 Strong Biomarker [59]
BCL2L1 TTRE6AX Strong Biomarker [60]
BIRC5 TTTPU1G Strong Biomarker [61]
BMP2 TTP3IGX Strong Biomarker [62]
BMP4 TTD3BSX Strong Genetic Variation [62]
BRCA2 TTUARD6 Strong Genetic Variation [63]
BUB1 TT78309 Strong Genetic Variation [64]
CA12 TTSYM0R Strong Biomarker [65]
CALR TTUZ7OA Strong Therapeutic [66]
CASP6 TTKW4ML Strong Genetic Variation [67]
CASP8 TT6SZNG Strong Biomarker [68]
CBR1 TTVG0SN Strong Biomarker [69]
CD1A TTBGTFN Strong Biomarker [70]
CD209 TTBXIM9 Strong Biomarker [71]
CD44 TTWFBT7 Strong Genetic Variation [72]
CD55 TT5Z9WY Strong Altered Expression [73]
CD83 TTT9MRQ Strong Biomarker [70]
CDC25C TTESBNC Strong Biomarker [74]
CDH3 TTARMD9 Strong Genetic Variation [62]
CDH5 TTXLCFO Strong Biomarker [75]
CDK1 TTH6V3D Strong Altered Expression [76]
CDKN1A TT9GUW0 Strong Altered Expression [77]
CDKN2A TTFTWQ8 Strong Genetic Variation [43]
CEACAM6 TTIGH2W Strong Biomarker [78]
CES1 TTMF541 Strong Altered Expression [79]
CFLAR TTJZQYH Strong Altered Expression [80]
CGA TTFC29G Strong Biomarker [81]
CHEK2 TT9ABMF Strong Biomarker [82]
CHKA TT10AWB Strong Altered Expression [83]
CHUK TT1F8OQ Strong Biomarker [84]
CLIC1 TT8KZG6 Strong Altered Expression [85]
COL7A1 TTBCOKN Strong Biomarker [75]
CREBBP TTFRCTK Strong Genetic Variation [43]
CRY1 TT5MLZR Strong Altered Expression [86]
CRY2 TTAO58M Strong Biomarker [86]
CSE1L TTTRULD Strong Biomarker [87]
CSK TTX6F0Q Strong Biomarker [88]
CTSH TT3G406 Strong Biomarker [89]
CUBN TT9YLCR Strong Genetic Variation [90]
CYP17A1 TTRA5BZ Strong Genetic Variation [91]
CYP1B1 TTI84H7 Strong Biomarker [92]
CYP2A6 TTAQ6ZW Strong Altered Expression [93]
CYP2C9 TTR40YJ Strong Genetic Variation [94]
DCLK1 TTOHTCY Strong Altered Expression [95]
DIABLO TTN74LE Strong Altered Expression [96]
DNMT1 TT6S2FE Strong Posttranslational Modification [97]
DPEP1 TTYUENF Strong Biomarker [98]
DPYSL2 TTZCW3T Strong Biomarker [99]
EIF5A TTIVCNR Strong Biomarker [100]
EIF5A2 TTH53G9 Strong Altered Expression [101]
ENAH TTY36UA Strong Altered Expression [102]
EPHA1 TTLFZVU Strong Biomarker [103]
EPHA5 TTV9KOD Strong Genetic Variation [104]
EPHB4 TTI4ZX2 Strong Biomarker [105]
ERAP1 TT60XFL Strong Genetic Variation [90]
ERBB2 TTR5TV4 Strong Genetic Variation [43]
ERBB3 TTSINU2 Strong Genetic Variation [43]
FADS2 TTT2VDU Strong Genetic Variation [55]
FAP TTGPQ0F Strong Altered Expression [106]
FBXW7 TT29KY7 Strong Genetic Variation [43]
FES TTLBY21 Strong Biomarker [107]
FGF19 TTGCH11 Strong Biomarker [108]
FGF7 TTFY134 Strong Biomarker [109]
FHIT TTMS54D Strong Altered Expression [110]
FHL1 TTI7ENL Strong Altered Expression [111]
FKBP5 TT0J5KQ Strong Genetic Variation [62]
FOLR2 TTT54CI Strong Altered Expression [112]
FZD7 TTUQMO5 Strong Biomarker [113]
GATA3 TT45KOB Strong Genetic Variation [114]
GATA4 TT1VDN2 Strong Biomarker [115]
GGH TTZJRL0 Strong Altered Expression [116]
GJC1 TTEP7OC Strong Posttranslational Modification [117]
GNA11 TTSRXJW Strong Altered Expression [118]
GRIN2A TTKJEMQ Strong Altered Expression [119]
HCRTR1 TT60Q8D Strong Biomarker [120]
HDAC1 TT6R7JZ Strong Biomarker [121]
HOXB13 TTZ6I58 Strong Biomarker [118]
HRH4 TTXJ178 Strong Altered Expression [122]
HSD11B1 TTN7BL9 Strong Altered Expression [123]
HSPE1 TTWYMFE Strong Biomarker [124]
ID1 TTBXVDE Strong Altered Expression [125]
IDH1 TTV2A1R Strong Genetic Variation [43]
IFNA2 TTSIUJ9 Strong Therapeutic [126]
IGFBP3 TTZHNQA Strong Biomarker [33]
ITGA4 TTJMF9P Strong Biomarker [127]
KCNH1 TT9XKUC Strong Genetic Variation [63]
KISS1 TTU2O6T Strong Altered Expression [128]
KLF4 TTTI53X Strong Altered Expression [129]
KLRK1 TTLRN4A Strong Altered Expression [130]
KSR1 TTHL1TV Strong Biomarker [105]
L1CAM TTC9D3K Strong Altered Expression [131]
LAMB3 TT2WOUQ Strong Biomarker [132]
LGMN TTPTWV5 Strong Altered Expression [133]
LGR5 TTTSGRH Strong Biomarker [134]
LPAR1 TTQ6S1K Strong Genetic Variation [62]
LRP1 TTF2V7I Strong Genetic Variation [62]
LRP6 TTSXOWE Strong Posttranslational Modification [135]
MAGEA1 TT63M7Q Strong Genetic Variation [136]
MAP2K1 TTIDAPM Strong Genetic Variation [43]
MASP2 TTR01E9 Strong Altered Expression [137]
MCM7 TT1RM3F Strong Altered Expression [138]
MGLL TTZ963I Strong Biomarker [139]
MGMT TTJ8DV7 Strong Posttranslational Modification [140]
MKI67 TTB4UNG Strong Biomarker [42]
MMP1 TTMX39J Strong Biomarker [141]
MMP10 TTXLEG7 Strong Biomarker [142]
MMP11 TTZW4MV Strong Biomarker [142]
MMP3 TTUZ2L5 Strong Altered Expression [143]
MTDH TTH6SA5 Strong Biomarker [144]
MTHFR TTQWOU1 Strong Genetic Variation [145]
MUC15 TTGQ6MI Strong Altered Expression [146]
MUC5AC TTEL90S Strong Biomarker [147]
MUTYH TTNB0ZK Strong Genetic Variation [148]
MYC TTNQ5ZP Strong Biomarker [62]
NAMPT TTD1WIG Strong Biomarker [149]
NCR1 TTQNRJM Strong Biomarker [150]
NFE2L2 TTA6ZN2 Strong Therapeutic [151]
NOD2 TTYPUHA Strong Biomarker [152]
NOTCH4 TTXDIK2 Strong Genetic Variation [27]
NPR1 TTM9IYA Strong Altered Expression [153]
NQO1 TT8XK6L Strong Biomarker [154]
NR0B1 TTTK36V Strong Biomarker [155]
NR4A2 TT9HKN3 Strong Biomarker [156]
NR5A2 TTAU3SY Strong Biomarker [157]
NRP2 TTRXUVC Strong Altered Expression [158]
NTSR1 TTTUMEP Strong Posttranslational Modification [159]
NUAK1 TT65FL0 Strong Biomarker [160]
ODC1 TTUMGNO Strong Biomarker [161]
OLFM4 TTK1CX7 Strong Altered Expression [162]
OPHN1 TTU7HRD Strong Altered Expression [163]
PARP1 TTVDSZ0 Strong Biomarker [164]
PBK TTMY6BZ Strong Biomarker [165]
PDCD1 TTNBFWK Strong Biomarker [166]
PDXP TT9UYG4 Strong Biomarker [167]
PEBP1 TT1BGU8 Strong Posttranslational Modification [168]
PHGDH TT8DRCK Strong Genetic Variation [169]
PIGU TT2LHI6 Strong Genetic Variation [62]
PIM2 TT69J2Z Strong Biomarker [170]
PKLR TT31N4S Strong Altered Expression [171]
PLA2G2A TTO8QRU Strong Altered Expression [172]
PLAUR TTNOSTX Strong Genetic Variation [173]
PLCG1 TT6T4JI Strong Altered Expression [174]
PLD1 TT3T17P Strong Altered Expression [175]
PLD2 TTRLMKF Strong Biomarker [176]
PMS1 TTX1ISF Strong Biomarker [177]
POLB TTA0XPV Strong Biomarker [178]
POSTN TT8ALTZ Strong Biomarker [179]
PPARG TTT2SVW Strong Posttranslational Modification [180]
PPARGC1B TTKSQ3W Strong Altered Expression [181]
PPT1 TTSQC14 Strong Altered Expression [182]
PRDX5 TTLPJWH Strong Altered Expression [183]
PRKCB TTYPXQF Strong Biomarker [184]
PRKCE TT57MT2 Strong Biomarker [184]
PRNP TTY5F9C Strong Biomarker [185]
PROM1 TTXMZ81 Strong Altered Expression [48]
PSMB8 TTEAD9J Strong Altered Expression [186]
PTGES TTYLQ8V Strong Altered Expression [187]
PTP4A3 TT7YM8D Strong Altered Expression [188]
PTPN13 TT405FP Strong Genetic Variation [189]
RAC1 TT2M9CG Strong Altered Expression [190]
RAF1 TTAN5W2 Strong Genetic Variation [43]
REG4 TTVZEHU Strong Altered Expression [191]
RET TT4DXQT Strong Biomarker [192]
RHOA TTP2U16 Strong Genetic Variation [43]
RNF43 TTD91BL Strong Altered Expression [193]
RNF6 TT4S09X Strong Altered Expression [194]
RSPO1 TTI9HL4 Strong Altered Expression [38]
RSPO3 TT7HJTF Strong Biomarker [195]
RUNX3 TTKCVO7 Strong Posttranslational Modification [196]
SCGB2A2 TT1W3RE Strong Biomarker [197]
SDC1 TTYDSVG Strong Biomarker [198]
SERPINB5 TT1KW50 Strong Biomarker [199]
SFRP4 TTX8I1Y Strong Biomarker [200]
SGO1 TTBPKGD Strong Altered Expression [201]
SH2B3 TT36N7Z Strong Genetic Variation [55]
SIK2 TTCUGZR Strong Altered Expression [202]
SLC19A1 TT09I7D Strong Genetic Variation [203]
SLC1A5 TTF7WRM Strong Biomarker [155]
SLC22A16 TTITAVR Strong Genetic Variation [204]
SLC22A3 TTG2UMS Strong Genetic Variation [205]
SLCO1B3 TTU86P0 Strong Biomarker [206]
SLCO2A1 TTKVTQO Strong Genetic Variation [27]
SMAD3 TTHQZV7 Strong Genetic Variation [62]
SMAD6 TTON5JB Strong Genetic Variation [62]
SMAD7 TT0J32Z Strong Genetic Variation [55]
SMAD9 TTX8EBV Strong Genetic Variation [62]
SNCG TT5TQNZ Strong Altered Expression [207]
SORD TTLSRBZ Strong Altered Expression [208]
SPARC TTBQFM7 Strong Biomarker [209]
SPDEF TT2ZUPY Strong Altered Expression [210]
SRC TT6PKBN Strong Altered Expression [211]
SSTR2 TTZ6T9E Strong Altered Expression [212]
ST14 TTPRO7W Strong Altered Expression [213]
STRAP TT165DP Strong Altered Expression [214]
TDG TTEXRQD Strong Genetic Variation [215]
TDGF1 TTN7HMG Strong Altered Expression [216]
TDP2 TTYF26D Strong Genetic Variation [217]
TFF1 TTNOJIZ Strong Biomarker [218]
TFRC TT8MG4S Strong Biomarker [219]
THPO TTCG5PE Strong Altered Expression [220]
TIAM1 TTNU6I5 Strong Biomarker [221]
TK1 TTP3QRF Strong Biomarker [18]
TMPRSS2 TT1GM2Z Strong Biomarker [222]
TMSB4X TTMVAIU Strong Altered Expression [223]
TNFRSF4 TTL31H0 Strong Altered Expression [224]
TNFRSF9 TTPW9LJ Strong Biomarker [225]
TNFSF10 TTA5MS9 Strong Therapeutic [226]
TNFSF13 TTOI1RM Strong Biomarker [227]
TNKS TTVUSO7 Strong Genetic Variation [228]
TOP1 TTGTQHC Strong Altered Expression [229]
TOP2A TTCGY2K Strong Altered Expression [230]
TPP1 TTOVYPT Strong Altered Expression [182]
TREM1 TTHZQP0 Strong Altered Expression [231]
TRIM28 TTQ2BKV Strong Biomarker [62]
TRIM59 TT613U4 Strong Altered Expression [232]
TRPC6 TTRBT3W Strong Genetic Variation [62]
TRPM4 TTJ2HKA Strong Altered Expression [233]
TXNIP TTTLDZK Strong ModifyingMutation [234]
TYMP TTO0IB8 Strong Altered Expression [235]
TYMS TTP1UKZ Strong Biomarker [236]
UCHL1 TTX9IFP Strong Posttranslational Modification [237]
UGT1A1 TT34ZAF Strong Genetic Variation [238]
UMPS TTAFJUD Strong Genetic Variation [239]
USP7 TTXU3EQ Strong Biomarker [240]
VDR TTK59TV Strong Altered Expression [241]
VEGFC TT0QUFV Strong Altered Expression [242]
WRN TT2H5WQ Strong Posttranslational Modification [243]
XPO1 TTCJUR4 Strong Genetic Variation [43]
YAP1 TT8UN2D Strong Biomarker [62]
YES1 TT0SQ8J Strong Biomarker [244]
ABCA1 TTJW1GN Definitive Biomarker [47]
ABCA4 TTLB52K Definitive Biomarker [47]
ABCB11 TTUXCAF Definitive Biomarker [47]
ABCB4 TTJUXV6 Definitive Biomarker [47]
ABCC1 TTOI92F Definitive Biomarker [47]
ABCC3 TTVLG21 Definitive Biomarker [47]
ABCC4 TTUEAFL Definitive Biomarker [47]
ABCC8 TTP835K Definitive Biomarker [47]
ABCG1 TTMWDGU Definitive Biomarker [47]
AKT1 TTWTSCV Definitive Biomarker [245]
CD9 TTZEIBV Definitive Biomarker [246]
CFTR TTRLZHP Definitive Biomarker [47]
GAPDH TTUGSWA Definitive Biomarker [236]
KDM2A TT8XTY2 Definitive Biomarker [236]
KLK6 TTLPF4X Definitive Altered Expression [247]
LCT TTA0OSE Definitive Genetic Variation [248]
MAGEA3 TTWSKHD Definitive Posttranslational Modification [249]
PPOX TTNFMS9 Definitive Biomarker [236]
TGFBR1 TTP4520 Definitive Genetic Variation [250]
------------------------------------------------------------------------------------
⏷ Show the Full List of 314 DTT(s)
This Disease Is Related to 24 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC16A7 DTLT3UG Strong Altered Expression [251]
SLC25A26 DT8HR5O Strong Genetic Variation [62]
SLC25A3 DTCRIWV Strong Genetic Variation [252]
SLC26A3 DTN1FMD Strong Altered Expression [253]
SLC39A14 DTZ6IJW Strong Biomarker [254]
SLC39A7 DTDQSAM Strong Altered Expression [255]
SLC4A11 DTH2J1G Strong Altered Expression [256]
SLC5A8 DTE3TAW Strong Altered Expression [257]
SLC5A9 DT1CP40 Strong Biomarker [258]
SLC6A18 DTGQ7FH Strong Genetic Variation [62]
ABCA10 DTVU0E3 Definitive Biomarker [47]
ABCA12 DT7LDG0 Definitive Biomarker [47]
ABCA3 DT2T6VQ Definitive Biomarker [47]
ABCA5 DT195NK Definitive Biomarker [47]
ABCA6 DTLMZUF Definitive Biomarker [47]
ABCA8 DT9NXMV Definitive Biomarker [47]
ABCA9 DTE3V8W Definitive Biomarker [47]
ABCB5 DTKVEXO Definitive Biomarker [47]
ABCB6 DTF9Y2V Definitive Biomarker [47]
ABCC5 DTYVM24 Definitive Biomarker [47]
ABCC6 DT582KR Definitive Biomarker [47]
ABCD2 DT4MBHD Definitive Biomarker [47]
ABCD3 DTGLZO4 Definitive Biomarker [47]
ABCD4 DTI8AFW Definitive Biomarker [47]
------------------------------------------------------------------------------------
⏷ Show the Full List of 24 DTP(s)
This Disease Is Related to 27 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
ADH1B DEEN9RD Limited Genetic Variation [4]
MTRR DE6NIY9 Limited Biomarker [259]
PRODH DEVJIHS Limited Biomarker [260]
NT5C DE4E31Z Disputed Biomarker [18]
ADH1C DEM1HNL Strong Genetic Variation [261]
AKR1B10 DEP6GT1 Strong Altered Expression [262]
BAAT DERA3OF Strong Genetic Variation [263]
CES2 DETHCPD Strong Altered Expression [264]
CYP1A1 DE6OQ3W Strong Genetic Variation [265]
EPHX1 DELB4KP Strong Biomarker [266]
FPGS DECWT2V Strong Biomarker [18]
GSTM1 DEYZEJA Strong Biomarker [267]
HK1 DEDMAGE Strong Biomarker [268]
HPGD DEHKSC6 Strong Biomarker [69]
NAT1 DE7OAB3 Strong Genetic Variation [269]
NAT2 DER7TA0 Strong Genetic Variation [270]
NNMT DECVGJ3 Strong Altered Expression [271]
PARK7 DEPOVCH Strong Altered Expression [272]
PER1 DE9HF0I Strong Biomarker [273]
SAT1 DEMWO83 Strong Altered Expression [274]
SULT1A1 DEYWLRK Strong Genetic Variation [275]
UGT1A6 DESD26P Strong Genetic Variation [276]
UGT1A7 DEZO4N3 Strong Genetic Variation [277]
FADS1 DE05S8C Definitive Biomarker [246]
PGM1 DEA3VM1 Definitive Biomarker [236]
PMM2 DEBRX3L Definitive Biomarker [236]
SULT2B1 DEZBN53 Definitive Biomarker [278]
------------------------------------------------------------------------------------
⏷ Show the Full List of 27 DME(s)
This Disease Is Related to 465 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACTR2 OT3C8U5T Limited Altered Expression [279]
ADAM23 OTVWT6JZ Limited Posttranslational Modification [280]
ARHGAP8 OT19H5Q9 Limited Altered Expression [281]
ATP6V0A1 OT1IK0KA Limited Altered Expression [282]
B4GALT1 OTBCXEK7 Limited Biomarker [283]
CBFB OTIAC6W4 Limited Altered Expression [284]
CENPH OTPOO9LK Limited Altered Expression [285]
CLDN1 OT27KV99 Limited Biomarker [286]
CLDN12 OTO55YZI Limited Altered Expression [287]
CLDN8 OT7IIWXG Limited Altered Expression [287]
CNOT7 OTJBKCPI Limited Altered Expression [288]
CNPY2 OTGY8ESX Limited Altered Expression [289]
CTU1 OTNTM9D1 Limited Biomarker [290]
EMX2 OT0V8OYK Limited Altered Expression [291]
FUT7 OTJF6BSN Limited Altered Expression [292]
GSTT2 OTANW3TJ Limited Genetic Variation [293]
HLTF OTRX2OSF Limited Genetic Variation [294]
HNRNPF OTSMBXMF Limited Altered Expression [295]
ID4 OTPMJ39I Limited Altered Expression [296]
KLK11 OT5PKX7Y Limited Altered Expression [297]
LAMP3 OTN0XL3W Limited Altered Expression [298]
LLGL1 OTAIQSXZ Limited Altered Expression [299]
MCM2 OTGGORIQ Limited Biomarker [300]
MOB1A OTSPBZ4Z Limited Altered Expression [301]
MYOD1 OTV2S79X Limited Posttranslational Modification [302]
NKD1 OTY3MO97 Limited Genetic Variation [303]
NR2F6 OTNVO2B6 Limited Altered Expression [304]
PCNX2 OT90S9W6 Limited Biomarker [305]
PDHX OTG7O271 Limited Altered Expression [20]
POLR2F OTF9T8I2 Limited Altered Expression [282]
PPP1R3A OTJL9VYP Limited Altered Expression [306]
RAD50 OTYMU9G1 Limited Biomarker [307]
RASAL1 OTAHUNN7 Limited Altered Expression [308]
RASL11A OTDO6CMY Limited Altered Expression [309]
RIN1 OTPBROUD Limited Biomarker [310]
SELENBP1 OT3NZNTR Limited Biomarker [311]
SELENOP OT02B8IR Limited Biomarker [32]
SEMG1 OT6Z4BPQ Limited Genetic Variation [312]
SOX7 OTOZOFAG Limited Altered Expression [313]
TAF1B OTMZB09B Limited Biomarker [305]
TCF7 OT1ID822 Limited Altered Expression [314]
TCN2 OT41D0L3 Limited Biomarker [259]
TMEM8B OTJZWPS6 Limited Altered Expression [315]
TRMT9B OTU3UPEE Limited Altered Expression [316]
BOLL OT5FAEJJ Disputed Biomarker [317]
CABLES1 OTMN4XSX Disputed Biomarker [318]
CABYR OTKYMT99 Disputed Biomarker [317]
CD109 OTDADBM4 Disputed Biomarker [33]
CDH7 OTQEXCKU Disputed Biomarker [319]
CHD5 OTS5EVHH Disputed Biomarker [33]
CTBP1 OTVYH2DH Disputed Biomarker [320]
EFEMP1 OTZVUOOB Disputed Biomarker [317]
EYA4 OTINGR3Z Disputed Biomarker [33]
FBLN2 OTEHR7N7 Disputed Biomarker [317]
FBN2 OT3KYJQL Disputed Biomarker [33]
FLNC OT3F8J6Y Disputed Biomarker [33]
FOXL2 OTFRQUYL Disputed Biomarker [317]
GNB4 OTC1GPHA Disputed Biomarker [317]
GRID1 OTJ3WIKC Disputed Biomarker [33]
GSTM3 OTLA2WJT Disputed Biomarker [317]
GUCY1A2 OTR6DVAA Disputed Biomarker [33]
HAPLN1 OTXWR9TJ Disputed Biomarker [33]
HOXD1 OTN4V9ZF Disputed Biomarker [317]
ICAM5 OTDGGAFH Disputed Biomarker [33]
JPH3 OTHTJO2I Disputed Biomarker [317]
LAMA1 OTQZMP86 Disputed Biomarker [33]
LGR6 OTPZ1PWR Disputed Biomarker [33]
LRRC3B OT9VDGPR Disputed Biomarker [321]
NEURL1 OT2C4P70 Disputed Biomarker [317]
NME2 OTCYGLHV Disputed Biomarker [18]
NRCAM OT80HHQ2 Disputed Biomarker [33]
NTNG1 OTF48IID Disputed Biomarker [33]
PPM1E OTXRH3YA Disputed Biomarker [33]
PPP1R14A OTQODWZB Disputed Biomarker [317]
PTPRD OTZPJ3GX Disputed Biomarker [33]
RNF111 OTO3QT6Q Disputed Genetic Variation [322]
SH3TC1 OT0HYZIU Disputed Biomarker [33]
SLC22A15 OT60WAAI Disputed Biomarker [33]
STARD8 OTY9IAKW Disputed Biomarker [33]
SYNE1 OTSBSLUH Disputed Biomarker [33]
TCERG1L OTSBSCLF Disputed Biomarker [33]
ADIPOR2 OT2HDTL8 moderate Altered Expression [323]
CCND2 OTDULQF9 moderate Genetic Variation [55]
DSC1 OTNII6GZ moderate Biomarker [324]
DSC2 OTODVH8K moderate Biomarker [324]
DSC3 OTYG47F8 moderate Biomarker [324]
ERCC2 OT1C8HQ4 moderate Genetic Variation [325]
EXTL3 OT2BRUBN moderate Altered Expression [326]
KLRC2 OTT4N86S moderate Altered Expression [327]
MLH3 OT91PPBI moderate Genetic Variation [328]
OXA1L OTS0BFRD moderate Altered Expression [329]
SFRP2 OT8GZ0CA moderate Posttranslational Modification [330]
ST13 OTNML6UP moderate Altered Expression [331]
ACAD8 OT3JI5GB Strong Biomarker [332]
ACOXL OTW680HT Strong Genetic Variation [114]
ACP1 OTJ9CKLU Strong Genetic Variation [333]
ACTR1B OTGBCKLO Strong Genetic Variation [334]
ACTRT3 OT2U08K8 Strong Genetic Variation [334]
ADAMTSL3 OTMC2WFG Strong Genetic Variation [335]
ADGRE2 OTUYJVYG Strong Altered Expression [336]
ADGRE5 OTTSB84Q Strong Altered Expression [337]
ADGRG1 OTQBB8NT Strong Biomarker [338]
AIM2 OT86QUI8 Strong Biomarker [339]
AKAP10 OTPNFTOU Strong Genetic Variation [340]
ALOX15B OTWQQ08W Strong Altered Expression [341]
ARHGDIA OTEXWJDO Strong Biomarker [342]
ARID1A OTRWDV3P Strong Biomarker [343]
ARL11 OTF6UDDB Strong Genetic Variation [344]
ARL4C OTQ3QNNU Strong Biomarker [345]
ARNT OTMSIEZY Strong Biomarker [9]
ASAH2 OT47TIF3 Strong Biomarker [346]
ASS1 OT4ZMG0Q Strong Biomarker [347]
ATF1 OT251CI0 Strong Genetic Variation [62]
ATXN7 OTL3YF1H Strong Biomarker [348]
AXIN1 OTRGZGZ5 Strong Biomarker [349]
AXIN2 OTRMGQNU Strong Posttranslational Modification [350]
B3GNT6 OTAX8BNJ Strong Altered Expression [351]
BAALC OTUZSRVF Strong Genetic Variation [352]
BABAM1 OTCFPER6 Strong Genetic Variation [63]
BAG1 OTRQNIA4 Strong Altered Expression [353]
BCAS1 OTQKJR81 Strong Altered Expression [256]
BHLHE22 OTZUQY5L Strong Biomarker [354]
BICC1 OTYRKIJ1 Strong Genetic Variation [91]
BLM OTEJOAJX Strong Genetic Variation [355]
BMP3 OTCTI0UW Strong Biomarker [356]
BMP5 OTC0Y6E0 Strong Genetic Variation [62]
BOC OTXBCY9W Strong Biomarker [62]
BTBD9 OTWQ6GA3 Strong Genetic Variation [357]
BTG4 OTT3TKPI Strong Posttranslational Modification [358]
BUB1B OT8KME51 Strong Biomarker [359]
CABLES2 OTGD9A2A Strong Genetic Variation [55]
CAPN10 OTS9LJW4 Strong Genetic Variation [360]
CASP8AP2 OTTWT68S Strong Genetic Variation [189]
CBLN2 OT29SSBE Strong Genetic Variation [357]
CD226 OT4UG0KB Strong Genetic Variation [319]
CDC42 OT5QBC5M Strong Altered Expression [361]
CDC5L OTTPFUU5 Strong Biomarker [362]
CDH17 OT9EV2XK Strong Biomarker [363]
CDK2AP1 OTNFOHDJ Strong Altered Expression [364]
CDX1 OTOHTMJE Strong Altered Expression [365]
CEACAM7 OTKFDTZY Strong Biomarker [366]
CEMIP OTK80FYN Strong Altered Expression [367]
CENPA OT0NEJ4X Strong Altered Expression [368]
CFAP44 OT1273MD Strong Genetic Variation [357]
CHD1 OT9R9G0H Strong Genetic Variation [62]
CHFR OTRAD2TT Strong Genetic Variation [369]
CHPT1 OT4FJ0K3 Strong Biomarker [370]
CHRDL2 OTJU2I5H Strong Genetic Variation [62]
CLDN2 OTRF3D6Y Strong Altered Expression [371]
CLDN3 OT71MN9S Strong Altered Expression [372]
CLDN7 OTNE0XHQ Strong Biomarker [286]
CLEC3A OTTOAEGT Strong Genetic Variation [217]
CMTM3 OTS75IGC Strong Biomarker [373]
COL4A2 OTJK1LKN Strong Genetic Variation [62]
COL4A5 OTHG60RE Strong Altered Expression [374]
COL4A6 OTUREU5Z Strong Altered Expression [374]
COLCA1 OT8BP6UD Strong Genetic Variation [55]
COX2 OTTMVBJJ Strong Biomarker [45]
CRTC3 OTVIGVUW Strong Genetic Variation [334]
CSMD1 OTIVDSC4 Strong Genetic Variation [375]
CSTB OT3U0JF8 Strong Altered Expression [376]
CTNNBIP1 OTX9SBJG Strong Altered Expression [377]
CTNNBL1 OT6KLHPA Strong Altered Expression [378]
CTTN OTJRG4ES Strong Altered Expression [379]
CXCL5 OTZOUPCA Strong Altered Expression [380]
DACT1 OT19Z704 Strong Biomarker [62]
DACT2 OTNLCC0K Strong Altered Expression [381]
DACT3 OTSNQ55G Strong Posttranslational Modification [382]
DCBLD1 OTA702JK Strong Genetic Variation [383]
DCC OT2C1SHW Strong Genetic Variation [384]
DDX53 OTHK3EGZ Strong Genetic Variation [385]
DENND5B OTNDJJUR Strong Genetic Variation [27]
DHDDS OTVLYBUS Strong Biomarker [370]
DIP2B OTP6KH82 Strong Genetic Variation [90]
DKC1 OTX7DJR6 Strong Altered Expression [386]
DKK4 OTWCCVF6 Strong Altered Expression [387]
DNAJA3 OT61924T Strong Altered Expression [388]
DOCK3 OTF3YS2W Strong Genetic Variation [357]
DRG1 OTIFYMI3 Strong Genetic Variation [357]
DSCC1 OTPUVLZT Strong Altered Expression [389]
DUSP6 OT4H6RKW Strong Altered Expression [390]
DYNLRB1 OTWVKOFB Strong Genetic Variation [391]
E2F4 OTB3JFH4 Strong Genetic Variation [392]
ECT2L OTOSDMGV Strong Genetic Variation [217]
EEF1A1 OT00THXS Strong Genetic Variation [393]
EFCAB2 OTXEFI4O Strong Genetic Variation [27]
EFTUD2 OT3X7QG2 Strong Biomarker [394]
EIF3H OT61RBF5 Strong Biomarker [395]
EIF4A2 OT08H03R Strong Altered Expression [396]
EIF4ENIF1 OTZWDB2X Strong Genetic Variation [357]
ELOVL5 OT375W1Z Strong Genetic Variation [397]
EMILIN1 OT94R6M1 Strong Altered Expression [188]
ESM1 OT331Y8V Strong Altered Expression [398]
ETV4 OT8C98UZ Strong Altered Expression [399]
ETV6 OTCZMG61 Strong Genetic Variation [400]
EVL OTZ8ZDNY Strong Biomarker [33]
EXO1 OTI87RS5 Strong Biomarker [401]
EYA1 OTHU807A Strong Altered Expression [402]
FABP6 OTIRQWLW Strong Altered Expression [403]
FAM193A OTT0W53G Strong Genetic Variation [357]
FANCD2 OTVEB5LF Strong Genetic Variation [404]
FEN1 OT6QGG7O Strong Genetic Variation [334]
FGF20 OTJIQ8YZ Strong Biomarker [387]
FHL3 OTMPRLZ5 Strong Biomarker [62]
FLCN OTVM78XM Strong Genetic Variation [405]
FMN1 OT9CID5R Strong Genetic Variation [62]
FRY OT74IAG2 Strong Genetic Variation [63]
FRZB OTTO3DPY Strong Altered Expression [406]
FSD1 OT8P6PT3 Strong Biomarker [407]
FSD1L OTBQ48RF Strong Biomarker [407]
FUCA1 OTW71IK4 Strong Biomarker [408]
FXYD3 OT9PPRHE Strong Biomarker [409]
GAB2 OTBFN705 Strong Altered Expression [410]
GALNT12 OTVIBUST Strong Altered Expression [411]
GATA5 OTO81B63 Strong Biomarker [115]
GBP1 OTUM7RPJ Strong Biomarker [412]
GCNT3 OTQ9ALTR Strong Altered Expression [413]
GDF11 OTOSNMND Strong Altered Expression [414]
GIPC1 OTXLVCPJ Strong Altered Expression [415]
GIPC2 OT68YFO1 Strong Altered Expression [415]
GLRX3 OTUPAU1N Strong Biomarker [416]
GNAS OTMH8BKJ Strong Genetic Variation [27]
GNG12 OTOGF42G Strong Genetic Variation [357]
GPATCH1 OTQRDBY6 Strong Genetic Variation [417]
GPR143 OTWUA2AV Strong Genetic Variation [418]
GPX2 OTXI2NTI Strong Biomarker [419]
GPX4 OTRAFFX2 Strong Biomarker [420]
GUCA2A OTUSF75G Strong Biomarker [421]
H6PD OTO7TNDD Strong Altered Expression [422]
HAND1 OTN4IPVV Strong Altered Expression [423]
HECA OTWG3P6C Strong Biomarker [424]
HERC2 OTNQYKOB Strong Genetic Variation [357]
HHIP OT77RQYS Strong Genetic Variation [62]
HHLA2 OTYBTVQS Strong Altered Expression [425]
HLA-F OT76CM19 Strong Genetic Variation [357]
HMMR OT4M0JTZ Strong Altered Expression [77]
HNF1B OTSYIC3T Strong Genetic Variation [63]
HNRNPM OTFU3OEZ Strong Biomarker [426]
HOXD9 OTZ4GVR1 Strong Biomarker [427]
HSPA12A OTFOCDD6 Strong Genetic Variation [428]
HSPH1 OTVRR73T Strong Genetic Variation [429]
IDH2 OTTQA4PB Strong Genetic Variation [43]
IFITM1 OTECO1G8 Strong Biomarker [430]
IFNA1 OTPMKY0L Strong Therapeutic [431]
IL6ST OT1N9C70 Strong Biomarker [432]
ING4 OT0VVG4V Strong Therapeutic [433]
KCNIP4 OTB1BS0X Strong Genetic Variation [357]
KDM4D OTN6KAE6 Strong Altered Expression [434]
KIF2C OTJ8G3NP Strong Altered Expression [435]
KLF2 OTIP1UFX Strong Biomarker [62]
KLF5 OT1ABI9N Strong Genetic Variation [62]
KLF6 OTQY9S7F Strong Genetic Variation [436]
KLF9 OTBFEJRQ Strong Biomarker [437]
KRT18 OTVLQFIP Strong Altered Expression [438]
KRT20 OT4RB40L Strong Altered Expression [100]
KRT8 OTTM4X11 Strong Genetic Variation [63]
L1TD1 OTB2W20Y Strong Genetic Variation [27]
LAMA5 OTIIXE4M Strong Genetic Variation [62]
LAMC1 OTIG527N Strong Genetic Variation [55]
LCP1 OTK61F2A Strong Altered Expression [439]
LEMD1 OTII3FTO Strong Altered Expression [440]
LIMA1 OTONPC9R Strong Genetic Variation [441]
LMAN1 OTYHKDEO Strong Biomarker [442]
LRIG1 OTY5HZN5 Strong Genetic Variation [55]
LSAMP OTYXVQX2 Strong Genetic Variation [217]
LSR OTR8Y32X Strong Altered Expression [443]
LXN OTZQ2M6Y Strong Biomarker [444]
LYPD3 OTLR2PYX Strong Biomarker [445]
MACC1 OTV3DLX0 Strong Altered Expression [446]
MACF1 OTVIHD77 Strong Genetic Variation [17]
MAD2L1 OTXNGZCG Strong Biomarker [359]
MAD2L2 OT24ZO59 Strong Altered Expression [447]
MAF OT1GR3IZ Strong Biomarker [62]
MAL OTBM30SW Strong Biomarker [448]
MAMSTR OT4J6Z7G Strong Genetic Variation [334]
MAP9 OTZD5099 Strong Biomarker [449]
MBD4 OTWR9YXE Strong Genetic Variation [450]
MCC OTQVI1EM Strong Genetic Variation [451]
MEGF8 OT5G38CH Strong Altered Expression [311]
MEP1A OTY2Z48T Strong Biomarker [452]
MGAT4A OT0ZW5FM Strong Biomarker [453]
MIB1 OT5C404P Strong Biomarker [42]
MOS OTNMQPFJ Strong Genetic Variation [454]
MPG OTAHW80B Strong Genetic Variation [215]
MPZ OTAR2YXH Strong Biomarker [155]
MRE11 OTGU8TZM Strong Biomarker [307]
MSH6 OT46FP09 Strong Genetic Variation [455]
MTHFD1 OTMKHVWC Strong Genetic Variation [456]
MTX1 OTLSDNZO Strong Genetic Variation [63]
MUC13 OTWKS9MF Strong Altered Expression [457]
MUC2 OT3X4QVX Strong Biomarker [458]
MYBL2 OTZ3JX8Q Strong Altered Expression [459]
MYCL OT1MFQ5U Strong Genetic Variation [460]
MYH11 OTVNVWY3 Strong Genetic Variation [461]
MYNN OT61R1HP Strong Genetic Variation [462]
MYO16 OTMS3D8W Strong Genetic Variation [357]
MYRF OTKF6AEB Strong Genetic Variation [27]
MZF1 OTMVZCPW Strong Genetic Variation [62]
NABP1 OTFTNFHW Strong Genetic Variation [463]
NANP OTR0RNB1 Strong Biomarker [258]
NCOR1 OT04XNOU Strong Biomarker [464]
ND5 OT45LW1K Strong Genetic Variation [181]
NDP OTGDJ4US Strong Biomarker [465]
NEIL1 OTHBU5DJ Strong Genetic Variation [215]
NEIL2 OTV6JEON Strong Genetic Variation [215]
NEK10 OTN0JAYL Strong Genetic Variation [63]
NIPBL OTF6OOLU Strong Genetic Variation [466]
NLK OT2LETFS Strong Biomarker [467]
NPAS2 OTMRT2TS Strong Altered Expression [468]
NR2F2 OTJFS67N Strong Biomarker [469]
NXN OT35N40G Strong Genetic Variation [62]
OR1J2 OTIQTQHU Strong Genetic Variation [357]
OVOL2 OTFM1GKF Strong Altered Expression [121]
PA2G4 OT7IG7HT Strong Biomarker [470]
PATZ1 OT0X9WGR Strong Biomarker [471]
PAX8 OTRPD9MI Strong Biomarker [427]
PCDH10 OT2GIT0E Strong Posttranslational Modification [472]
PCNX1 OTFP8XHC Strong Genetic Variation [17]
PI3 OT47MTC3 Strong Altered Expression [473]
PIK3R1 OT5BZ1J9 Strong Genetic Variation [43]
PLCH1 OT6Z1L2E Strong Genetic Variation [474]
PLEKHG6 OTZWA27A Strong Genetic Variation [62]
PMAIP1 OTXEE550 Strong Altered Expression [60]
PMP22 OTXWYWCZ Strong Biomarker [155]
PMS2 OTNLWTMI Strong Genetic Variation [475]
PNKD OT6G9UXN Strong Genetic Variation [55]
PNN OT0HXICH Strong Altered Expression [476]
POLD3 OTEQEFQ2 Strong Genetic Variation [55]
POLE OTFM3MMU Strong Genetic Variation [43]
POU5F1B OT0FKQ51 Strong Genetic Variation [55]
PPP1R11 OTSHYPPW Strong Biomarker [477]
PPP1R21 OTWN6N7T Strong Genetic Variation [27]
PPP2R1A OTYA3GB4 Strong Genetic Variation [43]
PPP2R1B OTFIHQGD Strong Altered Expression [478]
PPRC1 OT6GB3WR Strong Altered Expression [181]
PRB2 OTAD4JZ0 Strong Biomarker [479]
PREX1 OTUTPVA9 Strong Genetic Variation [27]
PRR5 OTYHSGJL Strong Altered Expression [480]
PSMA7 OTPHI6ST Strong Biomarker [481]
PTPRH OTDUHQGF Strong Altered Expression [482]
PTPRU OTHDO0QG Strong Genetic Variation [252]
PTTG1 OTIMYS4W Strong Biomarker [483]
PXN OTVMMUOF Strong Biomarker [484]
PYCARD OT67RON3 Strong Posttranslational Modification [485]
RAD18 OTQ9PLNT Strong Genetic Variation [486]
RAD51B OTCJVRMY Strong Genetic Variation [63]
RAD51C OTUD6SY5 Strong Genetic Variation [348]
RALY OT78NNWY Strong Genetic Variation [63]
RASA3 OT9C54MN Strong Biomarker [487]
RASGRF1 OTNWJ7EN Strong Genetic Variation [488]
RASSF1 OTEZIPB7 Strong Posttranslational Modification [489]
RASSF2 OT2JHDO4 Strong Genetic Variation [490]
RASSF5 OT6Q41I2 Strong Posttranslational Modification [491]
RB1CC1 OTZK8PFX Strong Genetic Variation [492]
RBM3 OTAJ7R31 Strong Altered Expression [493]
RBSN OTAIAS93 Strong Biomarker [348]
REG1A OTMHUH1D Strong Biomarker [494]
RETREG3 OTEUQ2MI Strong Genetic Variation [217]
RFXANK OTDX1026 Strong Altered Expression [495]
RHBDD3 OTJ3OLC8 Strong Altered Expression [496]
RHPN2 OTTYWMF6 Strong Genetic Variation [55]
RIPOR3 OTHZ4RKK Strong Genetic Variation [62]
RMDN1 OTE1NB6U Strong Altered Expression [449]
RMDN2 OTK5WSFI Strong Altered Expression [449]
RMDN3 OTKO7AUM Strong Altered Expression [449]
RNASEH2B OT8KHYFY Strong Genetic Variation [497]
RNF146 OTE4CO7E Strong Biomarker [498]
RNF182 OT08FLHZ Strong Biomarker [75]
RNF20 OT9NK6ZT Strong Genetic Variation [466]
RNF4 OTCMXQRE Strong Genetic Variation [357]
RNGTT OT59E0KX Strong Genetic Variation [217]
RPH3AL OT9VFJEL Strong Genetic Variation [499]
RTEL1 OTI3PJCT Strong Genetic Variation [62]
S100A11 OTI57KDN Strong Biomarker [500]
SART3 OTC1AM7S Strong Biomarker [501]
SAT2 OT28QL7H Strong Altered Expression [502]
SATB2 OT2W80XC Strong Biomarker [62]
SBF2 OTBB8NO8 Strong Genetic Variation [334]
SCAF8 OTSCFMK3 Strong Genetic Variation [217]
SCG5 OTXSJMT1 Strong Biomarker [503]
SCO2 OTJQQDRS Strong Altered Expression [504]
SEPTIN4 OTD16B30 Strong Biomarker [505]
SEPTIN9 OT1VMRFQ Strong Posttranslational Modification [506]
SERPINE2 OTYF5340 Strong Altered Expression [507]
SFN OTLJCZ1U Strong Altered Expression [508]
SFRP1 OT0U9G41 Strong Posttranslational Modification [330]
SFRP5 OTLCVVSH Strong Posttranslational Modification [330]
SHROOM2 OTZ2FJ7Q Strong Genetic Variation [334]
SKI OT4KJ8F6 Strong Altered Expression [509]
SKIL OTNBXH32 Strong Biomarker [322]
SLC16A4 OT1YXBKC Strong Altered Expression [251]
SLC2A4RG OTW3LX8D Strong Genetic Variation [488]
SLIT1 OT35RBNT Strong Biomarker [118]
SMAD4 OTWQWCKG Strong Genetic Variation [43]
SMC1A OT9ZMRK9 Strong Genetic Variation [466]
SMC3 OTWGFRHD Strong Genetic Variation [466]
SNAI1 OTDPYAMC Strong Altered Expression [510]
SNAI2 OT7Y8EJ2 Strong Altered Expression [241]
SOX17 OT9H4WWE Strong Biomarker [511]
SPARCL1 OT74DWMV Strong Altered Expression [512]
SPATA13 OTQ8NPAW Strong Genetic Variation [513]
SPINK1 OTSUVAL2 Strong Altered Expression [514]
SPINT1 OT1CLR5L Strong Altered Expression [213]
SPSB2 OT7ZVT8R Strong Genetic Variation [91]
SRPX OT5B9LXS Strong Altered Expression [476]
SSPN OTYG2SL7 Strong Genetic Variation [515]
STAG3 OTEV0AOD Strong Genetic Variation [466]
SYBU OT3FQV7N Strong Altered Expression [449]
SYMPK OTYAUDXV Strong Genetic Variation [417]
TANC1 OTF6TZ8E Strong Genetic Variation [62]
TAPBP OTL81AVZ Strong Biomarker [516]
TBX3 OTM64N7K Strong Genetic Variation [463]
TCF4 OTB9ASTK Strong Biomarker [121]
TET2 OTKKT03T Strong Genetic Variation [62]
TFEB OTJUJJQY Strong Genetic Variation [334]
TFF3 OTJJDRTU Strong Altered Expression [517]
TFPI2 OTZCRWOR Strong Biomarker [518]
TGIF1 OTN9VHAG Strong Biomarker [519]
TIMP1 OTOXC51H Strong Biomarker [142]
TIMP4 OT8A68SW Strong Altered Expression [520]
TJP1 OTBDCUPK Strong Posttranslational Modification [521]
TMBIM1 OTE47B57 Strong Genetic Variation [55]
TMEFF2 OT1WZ2QO Strong Posttranslational Modification [522]
TMEM258 OTXSDU14 Strong Genetic Variation [27]
TMIGD2 OTWWAHTV Strong Biomarker [523]
TMTC1 OTZ7NW96 Strong Genetic Variation [217]
TNFRSF19 OTTVT4MB Strong Altered Expression [524]
TNFSF9 OTV9L89D Strong Biomarker [78]
TNN OTQK2AMX Strong Altered Expression [525]
TNS3 OTPG2D8Z Strong Genetic Variation [334]
TOMM34 OTH6MITE Strong Altered Expression [193]
TOX2 OT7RZRVK Strong Genetic Variation [62]
TP63 OT0WOOKQ Strong Biomarker [526]
TPD52 OTPKSK43 Strong Altered Expression [85]
TRAP1 OTNG0L8J Strong Biomarker [527]
TRIB3 OTG5OS7X Strong Biomarker [528]
TRIM47 OTM9DGUD Strong Altered Expression [529]
TRO OTRZQMU8 Strong Biomarker [530]
TTC22 OTFNNLI1 Strong Genetic Variation [62]
ABCA13 OTTHTUQN Definitive Biomarker [47]
ABCB10 OT1C44F9 Definitive Biomarker [47]
ABCE1 OTH19LOA Definitive Biomarker [47]
ANP32A OTRHPFO2 Definitive Biomarker [236]
ARMCX1 OTOGL58Z Definitive Altered Expression [531]
CACUL1 OT6P1ZVP Definitive Biomarker [236]
CALCOCO2 OTRGX0OV Definitive Biomarker [236]
CBX5 OT8VYY84 Definitive Biomarker [236]
CDH22 OTQEUWQN Definitive Biomarker [236]
CNPPD1 OT8G88R2 Definitive Biomarker [236]
DONSON OTN5HE0W Definitive Biomarker [236]
DPAGT1 OTYEJAGZ Definitive Biomarker [236]
ETV1 OT6PMJIK Definitive Biomarker [532]
GNB5 OT3ZSAXH Definitive Biomarker [236]
IPP OTCGBS3H Definitive Biomarker [236]
KDM4B OT5P1UPY Definitive Altered Expression [533]
MYO1A OTS80FOD Definitive Posttranslational Modification [534]
NUSAP1 OT85HIJ5 Definitive Biomarker [236]
PAIP2 OTFNVLSK Definitive Biomarker [236]
PHETA1 OT4IMC0X Definitive Biomarker [236]
PHLPP1 OTIFXW8D Definitive Altered Expression [535]
POLD1 OTWO4UCJ Definitive Biomarker [536]
SESN2 OT889IXY Definitive Biomarker [537]
SFXN1 OTL66767 Definitive Biomarker [236]
STIM2 OTYNXAW0 Definitive Altered Expression [538]
THSD1 OTKPGFHS Definitive Posttranslational Modification [539]
------------------------------------------------------------------------------------
⏷ Show the Full List of 465 DOT(s)

References

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2 Loss of activin receptor type 2 protein expression in microsatellite unstable colon cancers.Gastroenterology. 2004 Mar;126(3):654-9. doi: 10.1053/j.gastro.2004.01.008.
3 Adenosine kinase gene expression in human colorectal cancer.Nucleosides Nucleotides Nucleic Acids. 2008 Jun;27(6):750-4. doi: 10.1080/15257770802145629.
4 Polymorphisms of alcohol dehydrogenase 2 and aldehyde dehydrogenase 2 and colorectal cancer risk in Chinese males.World J Gastroenterol. 2008 Aug 28;14(32):5078-83. doi: 10.3748/wjg.14.5078.
5 AMACR expression in colorectal cancer is associated with left-sided tumor localization.Virchows Arch. 2008 Sep;453(3):243-8. doi: 10.1007/s00428-008-0646-1. Epub 2008 Aug 19.
6 Targeting CD24 for treatment of colorectal and pancreatic cancer by monoclonal antibodies or small interfering RNA. Cancer Res. 2008 Apr 15;68(8):2803-12.
7 Suppression of murine colitis and its associated cancer by carcinoembryonic antigen-specific regulatory T cells.Mol Ther. 2014 May;22(5):1018-28. doi: 10.1038/mt.2014.41. Epub 2014 Mar 6.
8 An Oncolytic Adenovirus Encoding Decorin and Granulocyte Macrophage Colony Stimulating Factor Inhibits Tumor Growth in a Colorectal Tumor Model by Targeting Pro-Tumorigenic Signals and via Immune Activation.Hum Gene Ther. 2017 Aug;28(8):667-680. doi: 10.1089/hum.2017.033.
9 Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia.Carcinogenesis. 2011 Feb;32(2):203-9. doi: 10.1093/carcin/bgq237. Epub 2010 Nov 16.
10 Overexpression of EphA4 gene and reduced expression of EphB2 gene correlates with liver metastasis in colorectal cancer.Int J Oncol. 2008 Sep;33(3):573-7.
11 TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors.Cancer Res. 2014 Nov 15;74(22):6693-704. doi: 10.1158/0008-5472.CAN-14-1331. Epub 2014 Sep 19.
12 Inverse correlation of the up-regulation of FZD10 expression and the activation of beta-catenin in synchronous colorectal tumors.Cancer Sci. 2009 Mar;100(3):405-12. doi: 10.1111/j.1349-7006.2008.01052.x. Epub 2008 Dec 24.
13 Altered expression of KCNK9 in colorectal cancers.APMIS. 2004 Sep;112(9):588-94. doi: 10.1111/j.1600-0463.2004.apm1120905.x.
14 (-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells. Chem Biol Interact. 2010 May 14;185(3):247-52. doi: 10.1016/j.cbi.2010.03.036. Epub 2010 Mar 25.
15 Microsomal glutathione S-transferase gene polymorphisms and colorectal cancer risk in a Han Chinese population.Int J Colorectal Dis. 2007 Oct;22(10):1185-94. doi: 10.1007/s00384-007-0308-9. Epub 2007 May 5.
16 Activation of MEK1 or MEK2 isoform is sufficient to fully transform intestinal epithelial cells and induce the formation of metastatic tumors.BMC Cancer. 2008 Nov 17;8:337. doi: 10.1186/1471-2407-8-337.
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285 Centromere protein H is up-regulated in primary human colorectal cancer and its overexpression induces aneuploidy.Cancer Res. 2005 Jun 1;65(11):4683-9. doi: 10.1158/0008-5472.CAN-04-3613.
286 Anti-Claudin-1 Conjugated to a Near-Infrared Fluorophore Targets Colon Cancer in PDOX MouseModels.J Surg Res. 2019 Oct;242:145-150. doi: 10.1016/j.jss.2019.04.048. Epub 2019 May 9.
287 Differential expression of genes encoding tight junction proteins in colorectal cancer: frequent dysregulation of claudin-1, -8 and -12.Int J Colorectal Dis. 2007 Jun;22(6):651-9. doi: 10.1007/s00384-006-0197-3. Epub 2006 Oct 18.
288 Analysis of the transcription regulator, CNOT7, as a candidate chromosome 8 tumor suppressor gene in colorectal cancer.Int J Cancer. 2003 Sep 10;106(4):505-509. doi: 10.1002/ijc.11264.
289 Decreasing CNPY2 Expression Diminishes Colorectal Tumor Growth and Development through Activation of p53 Pathway.Am J Pathol. 2016 Apr;186(4):1015-24. doi: 10.1016/j.ajpath.2015.11.012. Epub 2016 Feb 3.
290 Expression pattern of breast-cancer-associated protein pS2/BCEI in colorectal tumors.Int J Cancer. 1994 Jan 2;56(1):52-5. doi: 10.1002/ijc.2910560110.
291 EMX2 gene expression predicts liver metastasis and survival in colorectal cancer.BMC Cancer. 2017 Aug 22;17(1):555. doi: 10.1186/s12885-017-3556-2.
292 Alpha1,3 fucosyltransferase VII plays a role in colorectal carcinoma metastases by promoting the carbohydration of glycoprotein CD24.Oncol Rep. 2010 Jun;23(6):1609-17. doi: 10.3892/or_00000802.
293 GSTT2 promoter polymorphisms and colorectal cancer risk.BMC Cancer. 2007 Jan 25;7:16. doi: 10.1186/1471-2407-7-16.
294 Helicase-like transcription factor (Hltf) gene-deletion promotes oxidative phosphorylation (OXPHOS) in colorectal tumors of AOM/DSS-treated mice.PLoS One. 2019 Aug 28;14(8):e0221751. doi: 10.1371/journal.pone.0221751. eCollection 2019.
295 Altered expression and localization of creatine kinase B, heterogeneous nuclear ribonucleoprotein F, and high mobility group box 1 protein in the nuclear matrix associated with colon cancer.Cancer Res. 2006 Jan 15;66(2):763-9. doi: 10.1158/0008-5472.CAN-05-3771.
296 Cdc42 is highly expressed in colorectal adenocarcinoma and downregulates ID4 through an epigenetic mechanism.Int J Oncol. 2008 Jul;33(1):185-93.
297 KLK11 mRNA expression predicts poor disease-free and overall survival in colorectal adenocarcinoma patients.Biomark Med. 2014;8(5):671-85. doi: 10.2217/bmm.13.151.
298 Expression of lysosome-associated membrane proteins in human colorectal neoplasms and inflammatory diseases.Am J Pathol. 2001 Aug;159(2):449-55. doi: 10.1016/S0002-9440(10)61716-6.
299 Reduced expression of Hugl-1, the human homologue of Drosophila tumour suppressor gene lgl, contributes to progression of colorectal cancer.Oncogene. 2005 Apr 28;24(19):3100-9. doi: 10.1038/sj.onc.1208520.
300 mRNA expression of minichromosome maintenance 2 in colonic adenoma and adenocarcinoma.Eur J Cancer Prev. 2009 Feb;18(1):40-5. doi: 10.1097/CEJ.0b013e32830c8d5a.
301 Clinical significance of the loss of MATS1 mRNA expression in colorectal cancer.Int J Oncol. 2007 Aug;31(2):333-8.
302 Hypermethylation of the MYOD1 gene is a novel prognostic factor in patients with colorectal cancer.Int J Mol Med. 2004 Mar;13(3):413-7.
303 Mutations in the human naked cuticle homolog NKD1 found in colorectal cancer alter Wnt/Dvl/beta-catenin signaling.PLoS One. 2009 Nov 24;4(11):e7982. doi: 10.1371/journal.pone.0007982.
304 The orphan nuclear receptor EAR2 is overexpressed in colorectal cancer and it regulates survivability of colon cancer cells.Cancer Lett. 2011 Oct 28;309(2):137-44. doi: 10.1016/j.canlet.2011.05.025. Epub 2011 Jun 22.
305 Identification of MARCKS, FLJ11383 and TAF1B as putative novel target genes in colorectal carcinomas with microsatellite instability.Oncogene. 2002 Aug 1;21(33):5081-7. doi: 10.1038/sj.onc.1205703.
306 PPP1R3 gene (protein phosphatase 1) alterations in colorectal cancer and its relationship to metastasis.Oncol Rep. 2005 Jun;13(6):1223-7.
307 RAD50/MRE11/NBS1 proteins in relation to tumour development and prognosis in patients with microsatellite stable colorectal cancer.Histol Histopathol. 2008 Dec;23(12):1495-502. doi: 10.14670/HH-23.1495.
308 Decreased expression of the RAS-GTPase activating protein RASAL1 is associated with colorectal tumor progression.Gastroenterology. 2009 Jan;136(1):206-16. doi: 10.1053/j.gastro.2008.09.063. Epub 2008 Oct 2.
309 Induced Chromosomal Aneuploidy Results in Global and Consistent Deregulation of the Transcriptome of Cancer Cells.Neoplasia. 2019 Jul;21(7):721-729. doi: 10.1016/j.neo.2019.04.009. Epub 2019 Jun 4.
310 Analysis of RIN1 gene expression in colorectal cancer.Oncol Rep. 2007 May;17(5):1171-5.
311 Expression of selenium-binding protein 1 characterizes intestinal cell maturation and predicts survival for patients with colorectal cancer.Mol Nutr Food Res. 2008 Nov;52(11):1289-99. doi: 10.1002/mnfr.200700331.
312 Mutations in two short noncoding mononucleotide repeats in most microsatellite-unstable colorectal cancers.Cancer Res. 2005 Jun 1;65(11):4607-13. doi: 10.1158/0008-5472.CAN-05-0165.
313 Sox7 Is an independent checkpoint for beta-catenin function in prostate and colon epithelial cells.Mol Cancer Res. 2008 Sep;6(9):1421-30. doi: 10.1158/1541-7786.MCR-07-2175.
314 Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB.Cell. 2002 Oct 18;111(2):251-63. doi: 10.1016/s0092-8674(02)01015-2.
315 Expression of tumor related genes NGX6, NAG-7, BRD7 in gastric and colorectal cancer.World J Gastroenterol. 2003 Aug;9(8):1729-33. doi: 10.3748/wjg.v9.i8.1729.
316 Mapping of a candidate colorectal cancer tumor-suppressor gene to a 900-kilobase region on the short arm of chromosome 8.Genes Chromosomes Cancer. 2004 Jul;40(3):247-60. doi: 10.1002/gcc.20039.
317 Comparing the DNA hypermethylome with gene mutations in human colorectal cancer.PLoS Genet. 2007 Sep;3(9):1709-23. doi: 10.1371/journal.pgen.0030157. Epub 2007 Jul 31.
318 The Cables gene on chromosome 18q is silenced by promoter hypermethylation and allelic loss in human colorectal cancer.Am J Pathol. 2007 Nov;171(5):1509-19. doi: 10.2353/ajpath.2007.070331.
319 Prognostic and predictive relevance of DNAM-1, SOCS6 and CADH-7 genes on chromosome 18q in colorectal cancer.Oncology. 2005;68(2-3):246-55. doi: 10.1159/000086781. Epub 2005 Jul 7.
320 Adenomatous polyposis coli control of C-terminal binding protein-1 stability regulates expression of intestinal retinol dehydrogenases.J Biol Chem. 2006 Dec 8;281(49):37828-35. doi: 10.1074/jbc.M602119200. Epub 2006 Oct 6.
321 Epigenetic silencing of LRRC3B in colorectal cancer.Scand J Gastroenterol. 2009;44(1):79-84. doi: 10.1080/00365520802400834.
322 Enhancement of TGF- signaling responses by the E3 ubiquitin ligase Arkadia provides tumor suppression in colorectal cancer.Cancer Res. 2011 Oct 15;71(20):6438-49. doi: 10.1158/0008-5472.CAN-11-1645.
323 Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.Endocr Relat Cancer. 2008 Mar;15(1):289-99. doi: 10.1677/ERC-07-0197.
324 Desmocollin switching in colorectal cancer.Br J Cancer. 2006 Nov 20;95(10):1367-70. doi: 10.1038/sj.bjc.6603453. Epub 2006 Oct 31.
325 ERCC2 2251A>C genetic polymorphism was highly correlated with early relapse in high-risk stage II and stage III colorectal cancer patients: a preliminary study.BMC Cancer. 2008 Feb 12;8:50. doi: 10.1186/1471-2407-8-50.
326 Dysregulation of Reg gene expression occurs early in gastrointestinal tumorigenesis and regulates anti-apoptotic genes.Cancer Biol Ther. 2006 Dec;5(12):1714-20. doi: 10.4161/cbt.5.12.3469. Epub 2006 Dec 30.
327 Expansion of CMV-mediated NKG2C+ NK cells associates with the development of specific de novo malignancies in liver-transplanted patients.J Immunol. 2014 Jan 1;192(1):503-11. doi: 10.4049/jimmunol.1301951. Epub 2013 Dec 4.
328 Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome.Genes Chromosomes Cancer. 2009 Apr;48(4):340-50. doi: 10.1002/gcc.20644.
329 Sequestration of 9-Hydroxystearic Acid in FAHFA (Fatty Acid Esters of Hydroxy Fatty Acids) as a Protective Mechanism for Colon Carcinoma Cells to Avoid Apoptotic Cell Death.Cancers (Basel). 2019 Apr 12;11(4):524. doi: 10.3390/cancers11040524.
330 Silencing of secreted frizzled-related protein genes in MSI colorectal carcinogenesis.Hepatogastroenterology. 2008 Jul-Aug;55(85):1265-8.
331 Expression of ST13 in colorectal cancer and adjacent normal tissues.World J Gastroenterol. 2005 Jan 21;11(3):336-9. doi: 10.3748/wjg.v11.i3.336.
332 Ileal Pouch-Anal Anastomosis for Dysplasia or Cancer Complicating Inflammatory Bowel Disease: Is Total Mesorectal Excision Always Mandatory? An Analysis of 36 Consecutive Patients.J Crohns Colitis. 2017 Aug 1;11(8):936-941. doi: 10.1093/ecco-jcc/jjx044.
333 Crystal structure of the PTPL1/FAP-1 human tyrosine phosphatase mutated in colorectal cancer: evidence for a second phosphotyrosine substrate recognition pocket.J Biol Chem. 2005 Mar 4;280(9):8180-7. doi: 10.1074/jbc.M412211200. Epub 2004 Dec 20.
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335 ADAMTSL3/punctin-2, a gene frequently mutated in colorectal tumors, is widely expressed in normal and malignant epithelial cells, vascular endothelial cells and other cell types, and its mRNA is reduced in colon cancer.Int J Cancer. 2007 Oct 15;121(8):1710-6. doi: 10.1002/ijc.22882.
336 Expression and regulation of CD97 in colorectal carcinoma cell lines and tumor tissues.Am J Pathol. 2002 Nov;161(5):1657-67. doi: 10.1016/S0002-9440(10)64443-4.
337 CD97 overexpression in tumor cells at the invasion front in colorectal cancer (CC) is independently regulated of the canonical Wnt pathway.Mol Carcinog. 2006 Nov;45(11):881-6. doi: 10.1002/mc.20262.
338 GPR56 Drives Colorectal Tumor Growth and Promotes Drug Resistance through Upregulation of MDR1 Expression via a RhoA-Mediated Mechanism.Mol Cancer Res. 2019 Nov;17(11):2196-2207. doi: 10.1158/1541-7786.MCR-19-0436. Epub 2019 Aug 23.
339 Absent in Melanoma 2 (AIM2) is an important mediator of interferon-dependent and -independent HLA-DRA and HLA-DRB gene expression in colorectal cancers.Oncogene. 2012 Mar 8;31(10):1242-53. doi: 10.1038/onc.2011.320. Epub 2011 Aug 1.
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341 Expression of 15-lipoxygenase-1 in human colorectal cancer.Cancer Res. 1999 Jan 15;59(2):360-6.
342 Overexpression of Rho GDP-dissociation inhibitor alpha is associated with tumor progression and poor prognosis of colorectal cancer.J Proteome Res. 2008 Sep;7(9):3994-4003. doi: 10.1021/pr800271b. Epub 2008 Jul 24.
343 ARID1A loss impairs enhancer-mediated gene regulation and drives colon cancer in mice.Nat Genet. 2017 Feb;49(2):296-302. doi: 10.1038/ng.3744. Epub 2016 Dec 12.
344 Association of the ARLTS1 Cys148Arg variant with sporadic and familial colorectal cancer.Carcinogenesis. 2007 Aug;28(8):1687-91. doi: 10.1093/carcin/bgm098. Epub 2007 Apr 21.
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346 Functions of neutral ceramidase in the Golgi apparatus.J Lipid Res. 2018 Nov;59(11):2116-2125. doi: 10.1194/jlr.M088187. Epub 2018 Aug 28.
347 Argininosuccinate Synthase 1 is a Metabolic Regulator of Colorectal Cancer Pathogenicity.ACS Chem Biol. 2017 Apr 21;12(4):905-911. doi: 10.1021/acschembio.6b01158. Epub 2017 Mar 1.
348 Rad51C-ATXN7 fusion gene expression in colorectal tumors.Mol Cancer. 2016 Jun 13;15(1):47. doi: 10.1186/s12943-016-0527-1.
349 Colorectal cancer and genetic alterations in the Wnt pathway.Oncogene. 2006 Dec 4;25(57):7531-7. doi: 10.1038/sj.onc.1210059.
350 Epigenetic silencing of AXIN2 in colorectal carcinoma with microsatellite instability.Oncogene. 2006 Jan 5;25(1):139-46. doi: 10.1038/sj.onc.1209009.
351 Core 3 synthase is down-regulated in colon carcinoma and profoundly suppresses the metastatic potential of carcinoma cells.Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4572-7. doi: 10.1073/pnas.0407983102. Epub 2005 Mar 8.
352 Genetic susceptibility markers for a breast-colorectal cancer phenotype: Exploratory results from genome-wide association studies.PLoS One. 2018 Apr 26;13(4):e0196245. doi: 10.1371/journal.pone.0196245. eCollection 2018.
353 G-quadruplex located in the 5'UTR of the BAG-1 mRNA affects both its cap-dependent and cap-independent translation through global secondary structure maintenance.Nucleic Acids Res. 2019 Nov 4;47(19):10247-10266. doi: 10.1093/nar/gkz777.
354 Class III -tubulin Expression in Colorectal Neoplasms Is a Potential Predictive Biomarker for Paclitaxel Response.Anticancer Res. 2019 Feb;39(2):655-662. doi: 10.21873/anticanres.13160.
355 BLM heterozygosity and the risk of colorectal cancer.Science. 2002 Sep 20;297(5589):2013. doi: 10.1126/science.1074399.
356 Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development.Genes Chromosomes Cancer. 2008 Jun;47(6):449-60. doi: 10.1002/gcc.20552.
357 Bayesian and frequentist analysis of an Austrian genome-wide association study of colorectal cancer and advanced adenomas.Oncotarget. 2017 Oct 9;8(58):98623-98634. doi: 10.18632/oncotarget.21697. eCollection 2017 Nov 17.
358 Epigenetic silencing of microRNA-34b/c and B-cell translocation gene 4 is associated with CpG island methylation in colorectal cancer.Cancer Res. 2008 Jun 1;68(11):4123-32. doi: 10.1158/0008-5472.CAN-08-0325.
359 Aneuploidy is associated with TP53 expression but not with BRCA1 or TERT expression in sporadic colorectal cancer.Anticancer Res. 2009 Nov;29(11):4381-7.
360 Identification of a protective haplogenotype within CAPN10 gene influencing colorectal cancer susceptibility.J Gastroenterol Hepatol. 2007 Dec;22(12):2298-302. doi: 10.1111/j.1440-1746.2007.04843.x. Epub 2007 Jun 7.
361 MYC-nick promotes cell migration by inducing fascin expression and Cdc42 activation.Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5481-90. doi: 10.1073/pnas.1610994113. Epub 2016 Aug 26.
362 CDC5L Promotes hTERT Expression and Colorectal Tumor Growth.Cell Physiol Biochem. 2017;41(6):2475-2488. doi: 10.1159/000475916. Epub 2017 May 4.
363 Determination of Cadherin-17 in Tumor Tissues of Different Metastatic Grade Using a Single Incubation-Step Amperometric Immunosensor.Anal Chem. 2018 Sep 18;90(18):11161-11167. doi: 10.1021/acs.analchem.8b03506. Epub 2018 Sep 6.
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365 Cdx1 homeobox gene during human colon cancer progression.Oncogene. 2003 Sep 11;22(39):7913-21. doi: 10.1038/sj.onc.1206756.
366 Long-term prognostic value of detection of circulating colorectal cancer cells using CGM2 reverse transcriptase-polymerase chain reaction assay.Surgery. 2006 Apr;139(4):556-62. doi: 10.1016/j.surg.2005.09.025.
367 Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors.PLoS One. 2013 Jul 23;8(7):e69473. doi: 10.1371/journal.pone.0069473. Print 2013.
368 Overexpression and mistargeting of centromere protein-A in human primary colorectal cancer.Cancer Res. 2003 Jul 1;63(13):3511-6.
369 Coding region polymorphisms in the CHFR mitotic stress checkpoint gene are associated with colorectal cancer risk.Cancer Lett. 2008 Feb 18;260(1-2):170-9. doi: 10.1016/j.canlet.2007.10.036.
370 Survivin antagonizes chemotherapy-induced cell death of colorectal cancer cells.Oncotarget. 2018 Jun 12;9(45):27835-27850. doi: 10.18632/oncotarget.25600. eCollection 2018 Jun 12.
371 Tight Junction Protein Claudin-2 Promotes Self-Renewal of Human Colorectal Cancer Stem-like Cells.Cancer Res. 2018 Jun 1;78(11):2925-2938. doi: 10.1158/0008-5472.CAN-17-1869. Epub 2018 Mar 6.
372 Claudins upregulation in human colorectal cancer.FEBS Lett. 2005 Nov 7;579(27):6179-85. doi: 10.1016/j.febslet.2005.09.091. Epub 2005 Oct 13.
373 CMTM3, located at the critical tumor suppressor locus 16q22.1, is silenced by CpG methylation in carcinomas and inhibits tumor cell growth through inducing apoptosis.Cancer Res. 2009 Jun 15;69(12):5194-201. doi: 10.1158/0008-5472.CAN-08-3694. Epub 2009 Jun 9.
374 Loss of expression of type IV collagen alpha5 and alpha6 chains in colorectal cancer associated with the hypermethylation of their promoter region.Am J Pathol. 2006 Mar;168(3):856-65. doi: 10.2353/ajpath.2006.050384.
375 Somatic mutations, allele loss, and DNA methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) gene reveals association with early age of diagnosis in colorectal cancer patients.PLoS One. 2013;8(3):e58731. doi: 10.1371/journal.pone.0058731. Epub 2013 Mar 7.
376 Expression and epigenetic regulation of cystatin B in lung cancer and colorectal cancer.Pathol Res Pract. 2017 Dec;213(12):1568-1574. doi: 10.1016/j.prp.2017.06.007. Epub 2017 Jun 6.
377 Overexpression of Icat induces G(2) arrest and cell death in tumor cell mutants for adenomatous polyposis coli, beta-catenin, or Axin.Cancer Res. 2002 Jun 1;62(11):3322-6.
378 Serum response factor enhances liver metastasis of colorectal carcinoma via alteration of the E-cadherin/beta-catenin complex.Oncol Rep. 2009 Jan;21(1):57-63.
379 pTyr421 cortactin is overexpressed in colon cancer and is dephosphorylated by curcumin: involvement of non-receptor type 1 protein tyrosine phosphatase (PTPN1).PLoS One. 2014 Jan 22;9(1):e85796. doi: 10.1371/journal.pone.0085796. eCollection 2014.
380 Disrupted expression of CXCL5 in colorectal cancer is associated with rapid tumor formation in rats and poor prognosis in patients.Clin Cancer Res. 2008 Apr 15;14(8):2276-84. doi: 10.1158/1078-0432.CCR-07-4045.
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383 Genome-wide association study of colorectal cancer identifies six new susceptibility loci.Nat Commun. 2015 Jul 7;6:7138. doi: 10.1038/ncomms8138.
384 Epigenetic and genetic alterations in Netrin-1 receptors UNC5C and DCC in human colon cancer.Gastroenterology. 2007 Dec;133(6):1849-57. doi: 10.1053/j.gastro.2007.08.074. Epub 2007 Sep 5.
385 Non-thermal plasma induces immunogenic cell death in vivo in murine CT26 colorectal tumors.Oncoimmunology. 2018 Jul 26;7(9):e1484978. doi: 10.1080/2162402X.2018.1484978. eCollection 2018.
386 Real-time PCR quantification of human DKC1 expression in colorectal cancer.Acta Oncol. 2008;47(8):1598-9. doi: 10.1080/02841860801898616.
387 DICKKOPF-4 and -2 genes are upregulated in human colorectal cancer.Cancer Sci. 2009 Oct;100(10):1923-30. doi: 10.1111/j.1349-7006.2009.01272.x. Epub 2009 Jul 2.
388 Progression of colorectal cancers correlates with overexpression and loss of polarization of expression of the htid-1 tumor suppressor.Int J Mol Med. 2008 Jan;21(1):19-31.
389 Overexpression of cohesion establishment factor DSCC1 through E2F in colorectal cancer.PLoS One. 2014 Jan 17;9(1):e85750. doi: 10.1371/journal.pone.0085750. eCollection 2014.
390 Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis.J Cell Physiol. 2019 May;234(5):6731-6745. doi: 10.1002/jcp.27420. Epub 2018 Oct 1.
391 Genetic and epigenetic analysis of the putative tumor suppressor km23 in primary ovarian, breast, and colorectal cancers.Clin Cancer Res. 2006 Jun 15;12(12):3713-5. doi: 10.1158/1078-0432.CCR-06-0800.
392 Functional impact of colorectal cancer-associated mutations in the transcription factor E2F4.Int J Oncol. 2013 Dec;43(6):2015-22. doi: 10.3892/ijo.2013.2131. Epub 2013 Oct 8.
393 Characterization of a major colon cancer susceptibility locus (Ccs3) on mouse chromosome 3.Oncogene. 2010 Feb 4;29(5):647-61. doi: 10.1038/onc.2009.369. Epub 2009 Nov 16.
394 Spliceosome protein Eftud2 promotes colitis-associated tumorigenesis by modulating inflammatory response of macrophage.Mucosal Immunol. 2019 Sep;12(5):1164-1173. doi: 10.1038/s41385-019-0184-y. Epub 2019 Jul 5.
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396 Eukaryotic initiation factor 4A2 promotes experimental metastasis and oxaliplatin resistance in colorectal cancer.J Exp Clin Cancer Res. 2019 May 14;38(1):196. doi: 10.1186/s13046-019-1178-z.
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398 Correlation between expression and differentiation of endocan in colorectal cancer.World J Gastroenterol. 2008 Jul 28;14(28):4562-8. doi: 10.3748/wjg.14.4562.
399 Association of Ets-related transcriptional factor E1AF expression with overexpression of matrix metalloproteinases, COX-2 and iNOS in the early stage of colorectal carcinogenesis.Carcinogenesis. 2005 May;26(5):892-9. doi: 10.1093/carcin/bgi029. Epub 2005 Feb 3.
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401 MLH3 and EXO1 alterations in familial colorectal cancer patients not fulfilling Amsterdam criteria.Cancer Genet Cytogenet. 2007 Jul 15;176(2):172-4. doi: 10.1016/j.cancergencyto.2007.04.011.
402 EYA1 promotes tumor angiogenesis by activating the PI3K pathway in colorectal cancer.Exp Cell Res. 2018 Jun 1;367(1):37-46. doi: 10.1016/j.yexcr.2018.02.028. Epub 2018 Feb 27.
403 Fatty acid binding protein 6 is overexpressed in colorectal cancer.Clin Cancer Res. 2006 Sep 1;12(17):5090-5. doi: 10.1158/1078-0432.CCR-05-2045.
404 Overexpression of Rad51C splice variants in colorectal tumors.Oncotarget. 2015 Apr 20;6(11):8777-87. doi: 10.18632/oncotarget.3209.
405 Mutations of the Birt-Hogg-Dub (BHD) gene in sporadic colorectal carcinomas and colorectal carcinoma cell lines with microsatellite instability.J Med Genet. 2003 May;40(5):364-7. doi: 10.1136/jmg.40.5.364.
406 Hypermethylation and expression regulation of secreted frizzled-related protein genes in colorectal tumor.World J Gastroenterol. 2006 Nov 28;12(44):7113-7. doi: 10.3748/wjg.v12.i44.7113.
407 PTBP1-associated microRNA-1 and -133b suppress the Warburg effect in colorectal tumors.Oncotarget. 2016 Apr 5;7(14):18940-52. doi: 10.18632/oncotarget.8005.
408 Decreased expression of alpha-L-fucosidase gene FUCA1 in human colorectal tumors.Int J Mol Sci. 2013 Aug 19;14(8):16986-98. doi: 10.3390/ijms140816986.
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412 Angiostatic immune reaction in colorectal carcinoma: Impact on survival and perspectives for antiangiogenic therapy.Int J Cancer. 2008 Nov 1;123(9):2120-9. doi: 10.1002/ijc.23764.
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415 Molecular cloning and characterization of human GIPC2, a novel gene homologous to human GIPC1 and Xenopus Kermit.Int J Oncol. 2002 Mar;20(3):571-6.
416 Identification and distribution of thioredoxin-like 2 as the antigen for the monoclonal antibody MC3 specific to colorectal cancer.Proteomics. 2008 Jun;8(11):2220-9. doi: 10.1002/pmic.200700770.
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494 REG1A expression is a prognostic marker in colorectal cancer and associated with peritoneal carcinomatosis.Int J Cancer. 2008 Jul 15;123(2):409-413. doi: 10.1002/ijc.23466.
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501 Expression of tumor rejection antigens in colorectal carcinomas.Cancer. 2002 Mar 15;94(6):1636-41. doi: 10.1002/cncr.10421.
502 Adenovirus-mediated expression of spermidine/spermine N1-acetyltransferase gene induces S-phase arrest in human colorectal cancer cells.Oncol Rep. 2008 Nov;20(5):1229-35.
503 Common genetic variants at the CRAC1 (HMPS) locus on chromosome 15q13.3 influence colorectal cancer risk.Nat Genet. 2008 Jan;40(1):26-8. doi: 10.1038/ng.2007.41. Epub 2007 Dec 16.
504 Molecular factors of 5-fluorouracil metabolism in colorectal cancer: analysis of primary tumor and lymph node metastasis.Int J Oncol. 2006 Feb;28(2):527-33. doi: 10.3892/ijo.28.2.527.
505 Impaired expression of a human septin family gene Bradeion inhibits the growth and tumorigenesis of colorectal cancer in vitro and in vivo.Cancer Gene Ther. 2002 Jun;9(6):483-8. doi: 10.1038/sj.cgt.7700460.
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516 Involvement of the chaperone tapasin in HLA-B44 allelic losses in colorectal tumors.Int J Cancer. 2005 Feb 10;113(4):611-8. doi: 10.1002/ijc.20526.
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531 ALEX1 suppresses colony formation ability of human colorectal carcinoma cell lines.Cancer Sci. 2012 Jul;103(7):1267-71. doi: 10.1111/j.1349-7006.2012.02300.x. Epub 2012 May 17.
532 Promoter capture Hi-C-based identification of recurrent noncoding mutations in colorectal cancer.Nat Genet. 2018 Oct;50(10):1375-1380. doi: 10.1038/s41588-018-0211-z. Epub 2018 Sep 17.
533 Stimulation of -catenin and colon cancer cell growth by the KDM4B histone demethylase.Int J Oncol. 2014 Apr;44(4):1341-8. doi: 10.3892/ijo.2014.2279. Epub 2014 Jan 27.
534 Brush border myosin Ia has tumor suppressor activity in the intestine.Proc Natl Acad Sci U S A. 2012 Jan 31;109(5):1530-5. doi: 10.1073/pnas.1108411109. Epub 2012 Jan 18.
535 PHLPP is a negative regulator of RAF1, which reduces colorectal cancer cell motility and prevents tumor progression in mice.Gastroenterology. 2014 May;146(5):1301-12.e1-10. doi: 10.1053/j.gastro.2014.02.003. Epub 2014 Feb 11.
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537 The interaction of Hemin and Sestrin2 modulates oxidative stress and colon tumor growth. Toxicol Appl Pharmacol. 2019 Jul 1;374:77-85.
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