Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHN7CB)

Drug Name

Tributylstannanyl Drug Info

Synonyms

Tributyltin; tributylstannanyl; Tributlytin; Tributylstannic hydride; TRIBUTYL TIN; Tri-n-butylstannane hydride; UNII-4XDX163P3D; Tin, tri-n-butyl-, hydride; HSDB 6362; EINECS 211-704-4; BRN 3587329; 4XDX163P3D; Stannane, tri-n-butyl-, hydride; 20763-88-6; Tri-n-butyltin hydride, 97%; tri-n-butylstannyl radical; tributyl-tin; TBY; TBTH; AC1MHUMB; AC1Q2UP8; ACMC-1B91A; DTXSID0040709; CTK1A6693; MolPort-003-928-307; PIILXFBHQILWPS-UHFFFAOYSA-N; MolPort-035-869-643; EBD10558; ANW-35557; MFCD00009416; ZINC169748512; AKOS015909735

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Cross-matching ID

PubChem CID: 3032732
CAS Number: CAS 688-73-3
TTD Drug ID: DMHN7CB

Molecule-Related Drug Atlas

Molecule Type:

DTT

Drug Status:

Approved Drug(s)

Investigative Drug(s)

Download the Complete Related Drug List

Drug(s) Targeting Retinoic acid receptor RXR-alpha (RXRA)

Drug Name	Drug ID	Indication	ICD 11	Highest Status	REF
Alitretinoin	DMME8LH	Kaposi sarcoma	2B57	Approved	[2]
Bexarotene	DMOBIKY	Cutaneous T-cell lymphoma	2B01	Approved	[3]
2-chloro-5-nitro-N-phenylbenzamide	DMUGQIV	Discovery agent	N.A.	Investigative	[1]
AGN-34	DM5ECDM	Discovery agent	N.A.	Investigative	[4]
LG100754	DMEK4FY	Discovery agent	N.A.	Investigative	[5]
(5BETA)-PREGNANE-3,20-DIONE	DMVQ6RN	Discovery agent	N.A.	Investigative	[1]
Phytanic acid	DMSZ1RB	Discovery agent	N.A.	Investigative	[6]
CD3254	DM38MU1	Discovery agent	N.A.	Investigative	[7]
UVI3003	DM95UI1	Discovery agent	N.A.	Investigative	[8]
methoprene acid	DM58A0W	Discovery agent	N.A.	Investigative	[9]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

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Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Retinoic acid receptor RXR-alpha (RXRA)	TT6PEUO	RXRA_HUMAN	Inhibitor	[1]

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References

1	The Protein Data Bank. Nucleic Acids Res. 2000 Jan 1;28(1):235-42.
2	Retinoic acid receptors and retinoid X receptors: interactions with endogenous retinoic acids. Proc Natl Acad Sci U S A. 1993 Jan 1;90(1):30-4.
3	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.
4	Farnesoid X receptor: from structure to potential clinical applications. J Med Chem. 2005 Aug 25;48(17):5383-403.
5	The rexinoid LG100754 is a novel RXR:PPARgamma agonist and decreases glucose levels in vivo. Mol Endocrinol. 2001 Aug;15(8):1360-9.
6	Phytanic acid is a retinoid X receptor ligand. Eur J Biochem. 1996 Feb 15;236(1):328-33.
7	Co-regulator recruitment and the mechanism of retinoic acid receptor synergy. Nature. 2002 Jan 10;415(6868):187-92.
8	Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators thro... J Biol Chem. 2005 Jan 14;280(2):1625-33.
9	Activation of mammalian retinoid X receptors by the insect growth regulator methoprene. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):6157-60.