General Information of Disease (ID: DISMNGZ0)

Disease Name Thyroid gland carcinoma
Synonyms
thyroid cancer; head and neck cancer, thyroid; thyroid gland cancer; cancer of thyroid; cancer of the thyroid; carcinoma of thyroid gland; thyroid carcinoma; thyroid gland carcinoma; carcinoma of thyroid; carcinoma of the thyroid; carcinoma of the thyroid gland
Definition A carcinoma arising from the thyroid gland. It is usually an adenocarcinoma and includes the following main subtypes: follicular, papillary, medullary, poorly differentiated, and anaplastic.
Disease Hierarchy
DIS3VLDH: Thyroid cancer
DISH9F1N: Carcinoma
DISMNGZ0: Thyroid gland carcinoma
Disease Identifiers
MONDO ID
MONDO_0015075
MESH ID
D013964
UMLS CUI
C0549473
MedGen ID
107811
HPO ID
HP:0002890
Orphanet ID
100088

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 155 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
BMP1 TT0L58T Limited Biomarker [1]
CALCA TTVSFJW Limited Genetic Variation [2]
DICER1 TTTEOPU Limited Genetic Variation [3]
DUSP5 TTZN92A Limited Biomarker [4]
ENPP2 TTSCIM2 Limited Biomarker [5]
FAP TTGPQ0F Limited Altered Expression [6]
FYN TT2B9KF Limited Altered Expression [7]
GJB3 TTVRQ8L Limited Altered Expression [8]
IL32 TTD4G7L Limited Biomarker [9]
KSR1 TTHL1TV Limited Posttranslational Modification [10]
LASP1 TTZJA87 Limited Biomarker [11]
MAP4K4 TT6NI13 Limited Altered Expression [12]
MMP11 TTZW4MV Limited Biomarker [13]
MUC15 TTGQ6MI Limited Biomarker [14]
NOX4 TTQRBSJ Limited Biomarker [15]
PRKAR1A TTNAHEX Limited Genetic Variation [16]
RAPGEF3 TTOE7I0 Limited Biomarker [17]
RAPGEF4 TTOS63B Limited Biomarker [17]
S1PR2 TTVSMOH Limited Biomarker [18]
SCN10A TT90XZ8 Limited Biomarker [19]
SDHD TTVH9W8 Limited Genetic Variation [20]
SLC26A4 TT7X02I Limited Genetic Variation [21]
SLC6A9 TTHJTF7 Limited Biomarker [22]
SPHK1 TTOHFIY Limited Biomarker [23]
STOML2 TTOI329 Limited Altered Expression [24]
TIAM1 TTNU6I5 Limited Biomarker [25]
TNFRSF13B TTL9OD4 Limited Altered Expression [26]
TSG101 TTHU7JA Limited Biomarker [27]
YES1 TT0SQ8J Limited Altered Expression [28]
ATIC TT9NVXQ Disputed Biomarker [29]
FGF19 TTGCH11 Disputed Biomarker [30]
SORT1 TTRX9AV Disputed Biomarker [31]
STK4 TTCPLVN Disputed Biomarker [32]
ARAF TT5TURO moderate Genetic Variation [33]
BCAT2 TTF9OQ6 moderate Altered Expression [34]
CCNE2 TTLDRGX moderate Altered Expression [35]
CNTN1 TTPR8FK moderate Biomarker [36]
CSF2 TTNYZG2 moderate Biomarker [5]
EPO TTQG4NR moderate Biomarker [37]
EPOR TTAUX24 moderate Biomarker [37]
IDH1 TTV2A1R moderate Genetic Variation [38]
IFNA2 TTSIUJ9 moderate Therapeutic [39]
LIMK1 TTWL9TY moderate Biomarker [40]
MAPKAP1 TTWDKCL moderate Altered Expression [41]
MVD TTE5J6X moderate Altered Expression [42]
NDUFA13 TTRU1NG moderate Biomarker [43]
PDGFA TTSM78N moderate Biomarker [5]
PPARG TTT2SVW moderate Genetic Variation [44]
PRKCQ TT1MS7X moderate Biomarker [45]
PTGES2 TTWU04I moderate Biomarker [46]
RUNX2 TTD6SZ8 moderate Altered Expression [47]
RXRA TT6PEUO moderate Biomarker [48]
SSTR2 TTZ6T9E moderate Altered Expression [49]
TPCN1 TTODQE2 moderate Biomarker [50]
TRPC1 TTA76X0 moderate Biomarker [51]
VDAC1 TTAMKGB moderate Altered Expression [52]
WNK1 TTJ9UMX moderate Posttranslational Modification [53]
XRCC5 TTCB9KW moderate Altered Expression [54]
ACVR1B TTPKHTZ Strong Altered Expression [55]
AGK TTJETQC Strong Genetic Variation [56]
AKT3 TTO6SGY Strong Biomarker [57]
ALK TTPMQSO Strong Biomarker [58]
ARG2 TTV1AG6 Strong Biomarker [59]
ATM TTKBM7V Strong Genetic Variation [60]
BRD4 TTSRAOU Strong Biomarker [61]
BUB1 TT78309 Strong Altered Expression [62]
CA12 TTSYM0R Strong Biomarker [63]
CBX7 TTBN3HC Strong Biomarker [64]
CCKBR TTVFO0U Strong Altered Expression [65]
CCL2 TTNAY0P Strong Biomarker [66]
CCND1 TTFCJ7S Strong Biomarker [67]
CDH1 TTLAWO6 Strong Genetic Variation [68]
CDH5 TTXLCFO Strong Posttranslational Modification [69]
CDH6 TT9QHUK Strong Biomarker [70]
CDK2 TT7HF4W Strong Biomarker [71]
CDK5 TTL4Q97 Strong Biomarker [72]
CDKN1B TTLGFVW Strong Biomarker [73]
CHEK2 TT9ABMF Strong Biomarker [74]
CXCL10 TTQOVYA Strong Biomarker [75]
CXCR1 TTMWT8Z Strong Altered Expression [76]
CXXC5 TTVS4C3 Strong Altered Expression [77]
CYP19A1 TTSZLWK Strong Altered Expression [78]
CYP24A1 TT82UI1 Strong Biomarker [79]
DPEP1 TTYUENF Strong Genetic Variation [80]
EIF2AK2 TTXEZJ4 Strong Biomarker [81]
F9 TTFEZ5Q Strong Genetic Variation [82]
FGFR4 TT1KX2S Strong Biomarker [30]
GAS6 TT69QD2 Strong Biomarker [53]
GPER1 TTDSB34 Strong Biomarker [83]
GRK2 TTAZ3MN Strong Altered Expression [84]
HIF1A TTSN6QU Strong Genetic Variation [85]
HIPK2 TTOB49C Strong Biomarker [86]
HLA-G TTLKFB3 Strong Biomarker [87]
HMGA1 TTBA219 Strong Biomarker [88]
HMGA2 TTSTVM0 Strong Biomarker [89]
HRAS TT28ZON Strong Biomarker [90]
IDUA TT0IUKX Strong Biomarker [91]
IL1R2 TT51DEV Strong Genetic Variation [92]
IMP3 TTEJA2R Strong Biomarker [93]
ITCH TT5SEWD Strong Biomarker [94]
KEAP1 TT3Z6Y9 Strong Biomarker [95]
KLB TTARBVH Strong Altered Expression [96]
KRAS TTM8FR7 Strong Biomarker [97]
KRT19 TT3JF9E Strong Altered Expression [98]
LGR4 TTY6C71 Strong Altered Expression [99]
MAP2K1 TTIDAPM Strong Biomarker [100]
MAP2K7 TT6QY3J Strong Genetic Variation [101]
MCM7 TT1RM3F Strong Altered Expression [102]
MRGPRX1 TTIX6PK Strong Genetic Variation [103]
MTOR TTCJG29 Strong Biomarker [104]
NCOA4 TT8OY02 Strong Altered Expression [36]
NR1D1 TTAD1O8 Strong Genetic Variation [105]
NRAS TTW2R9X Strong Biomarker [106]
NRG1 TTEH395 Strong Biomarker [107]
NTRK3 TTXABCW Strong Biomarker [16]
OGFR TT6IEYX Strong Biomarker [108]
PAM TTF4ZPC Strong Biomarker [109]
PDPK1 TTYMGWX Strong Biomarker [110]
PLA2R1 TTHKW7D Strong Altered Expression [111]
PPARGC1B TTKSQ3W Strong Genetic Variation [85]
PPM1D TTENJAB Strong Genetic Variation [74]
PTGS2 TTVKILB Strong Biomarker [112]
PTPRJ TTWMKXP Strong Genetic Variation [113]
RARB TTISP28 Strong Biomarker [114]
RGS4 TTGTKX9 Strong Biomarker [115]
RHBDF2 TTH1ZOP Strong Biomarker [116]
RXFP1 TTMAHD1 Strong Altered Expression [117]
RXRB TTKLV96 Strong Biomarker [118]
SERPINB5 TT1KW50 Strong Posttranslational Modification [119]
SLC1A3 TT8WRDA Strong Altered Expression [120]
SLCO2B1 TTDL3UZ Strong Biomarker [121]
SMAD3 TTHQZV7 Strong Biomarker [122]
SORD TTLSRBZ Strong Genetic Variation [123]
SSTR3 TTJX3UE Strong Altered Expression [124]
STC1 TTDLUER Strong Biomarker [125]
TACSTD2 TTP2HE5 Strong Biomarker [126]
TEP1 TTQGAVX Strong Biomarker [127]
TERT TTQY2EJ Strong Genetic Variation [128]
THBS1 TTKI0H1 Strong Biomarker [129]
THRA TTTSEPU Strong Genetic Variation [105]
THRB TTGER3L Strong Biomarker [130]
TKTL1 TTNQ1J3 Strong Biomarker [131]
TP53BP1 TTX4UE9 Strong Altered Expression [132]
TTK TTP7EGM Strong Biomarker [91]
TXNIP TTTLDZK Strong Biomarker [133]
VCP TTHNLSB Strong Altered Expression [134]
WRN TT2H5WQ Strong Genetic Variation [135]
CCR6 TTFDB30 Definitive Biomarker [136]
ELAVL1 TTPC9D0 Definitive Biomarker [137]
FOLH1 TT9G4N0 Definitive Altered Expression [138]
GAP43 TTSGLN5 Definitive Biomarker [139]
IL13RA2 TTMPZ7V Definitive Biomarker [140]
PAK1 TTFN95D Definitive Biomarker [141]
PKM TT4LOT8 Definitive Biomarker [142]
SLIT2 TTDWK85 Definitive Biomarker [143]
------------------------------------------------------------------------------------
⏷ Show the Full List of 155 DTT(s)
This Disease Is Related to 2 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC16A2 DTQ8MP1 Limited Altered Expression [144]
SLC5A8 DTE3TAW moderate Genetic Variation [21]
------------------------------------------------------------------------------------
This Disease Is Related to 13 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
CYB5R3 DE4A3BL Limited Biomarker [145]
HIF1AN DEY1CBW Limited Biomarker [146]
MT1A DE5ME8A Limited Biomarker [147]
PTGDS DER3H9C Limited Altered Expression [148]
HPGD DEHKSC6 moderate Therapeutic [149]
UPP1 DEFZWAX moderate Altered Expression [150]
BAAT DERA3OF Strong Genetic Variation [105]
CYP1A1 DE6OQ3W Strong Altered Expression [151]
GGCT DEKW6PB Strong Biomarker [152]
GSTM1 DEYZEJA Strong Biomarker [153]
GSTT1 DE3PKUG Strong Genetic Variation [153]
NNMT DECVGJ3 Strong Altered Expression [154]
AKR1C2 DEOY5ZM Definitive Altered Expression [155]
------------------------------------------------------------------------------------
⏷ Show the Full List of 13 DME(s)
This Disease Is Related to 318 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
AFM OTPOR8IO Limited Biomarker [156]
AGPS OTFBFPV4 Limited Biomarker [157]
AKAP4 OTL4Z99V Limited Biomarker [158]
AMBP OTLU8GU8 Limited Altered Expression [159]
ANO5 OTOW8R6H Limited Altered Expression [160]
ATG9B OTJMJZW8 Limited Biomarker [161]
BAG3 OTVXYUDQ Limited Altered Expression [162]
BASP1 OTF4VS5G Limited Altered Expression [163]
BHLHE41 OTY9GJ1Y Limited Biomarker [164]
BID OTOSHSHU Limited Biomarker [161]
BLM OTEJOAJX Limited Altered Expression [165]
BTG2 OTZF6K1H Limited Altered Expression [166]
BUB3 OTU91HAU Limited Genetic Variation [62]
C14orf93 OTMHTPMZ Limited Biomarker [167]
CCL15 OTOGZ85M Limited Biomarker [168]
CETN1 OTGQ8JOZ Limited Altered Expression [145]
CITED1 OTUJQ3VL Limited Biomarker [169]
COPZ1 OTJXGQQW Limited Biomarker [170]
DIAPH1 OTZBYPLH Limited Biomarker [145]
DIPK2A OTL1DBIM Limited Biomarker [145]
EHF OTY6TPWD Limited Altered Expression [171]
EIF4A3 OTYYFE7K Limited Biomarker [172]
EPB41L4A OTJAFRTL Limited Genetic Variation [173]
FHOD3 OT1WUBQX Limited Genetic Variation [174]
FXYD5 OT81DIOD Limited Altered Expression [159]
FZD8 OTZ9IRFL Limited Altered Expression [175]
GATAD2A OTFM8D3O Limited Biomarker [176]
HMGN4 OTD7GPRL Limited Biomarker [177]
HORMAD2 OTL2ENWI Limited Altered Expression [178]
HUWE1 OTFH6BJS Limited Biomarker [179]
IFT88 OTDR3VBD Limited Altered Expression [180]
IGF2BP3 OTB97VIK Limited Altered Expression [181]
IL17RB OT0KDNSF Limited Altered Expression [182]
ING5 OTRNNSFM Limited Biomarker [183]
KIR2DS5 OTXLEN11 Limited Genetic Variation [184]
LETM1 OT8N4MRU Limited Altered Expression [185]
LRP4 OTO4M459 Limited Altered Expression [186]
LRRC34 OTSPZLKF Limited Genetic Variation [173]
MREG OT0LUIRG Limited Biomarker [187]
NCOA5 OTOGWTWB Limited Biomarker [188]
NFIL3 OTQH9HM3 Limited Biomarker [189]
NRCAM OT80HHQ2 Limited Biomarker [190]
PAX8 OTRPD9MI Limited Biomarker [191]
PCBP1 OTHN0TD7 Limited Altered Expression [192]
PCNX2 OT90S9W6 Limited Genetic Variation [173]
PEG3 OTHQW98S Limited Biomarker [193]
PIWIL2 OT1PXQIF Limited Biomarker [194]
POT1 OTNBXJCQ Limited Genetic Variation [195]
POU5F1B OT0FKQ51 Limited Genetic Variation [196]
RAB11A OTC4FW0J Limited Altered Expression [197]
RBMY1A1 OTM2F25H Limited Genetic Variation [198]
RBP2 OTR8QG5V Limited Biomarker [199]
RCC1 OT25AGMB Limited Genetic Variation [200]
RNASE1 OTKZ7CO9 Limited Altered Expression [201]
SDF4 OTQ7WFYW Limited Altered Expression [145]
SGSM3 OTIB1P8A Limited Altered Expression [91]
SLC35F2 OTSAD4EQ Limited Biomarker [202]
SPRY4 OT2VK9N0 Limited Biomarker [203]
SRGAP1 OTL89HGW Limited Genetic Variation [204]
SRP72 OTPV73W7 Limited Altered Expression [174]
STK17B OT4NYNO8 Limited Altered Expression [205]
SYTL2 OTUIOWKL Limited Altered Expression [24]
TCP1 OT1MGUX9 Limited Biomarker [206]
TCTN1 OTG5KEV8 Limited Biomarker [207]
TINAGL1 OTZZO56M Limited Altered Expression [208]
TPM3 OT5RU5G6 Limited Biomarker [16]
TRIM29 OT2DNESG Limited Altered Expression [209]
TRIM44 OT0B1T2B Limited Biomarker [210]
ADGRE2 OTUYJVYG Disputed Altered Expression [211]
ADGRE5 OTTSB84Q Disputed Altered Expression [211]
DCTN6 OTI8PIN9 Disputed Biomarker [212]
DDT OTF5HTYL Disputed Biomarker [213]
FOXE1 OT5IR5IT Disputed Altered Expression [214]
GPD2 OTV232Y7 Disputed Biomarker [215]
IFI27 OTI2XGIT Disputed Biomarker [212]
IQGAP1 OTZRWTGA Disputed Altered Expression [216]
MYO1F OTOAV4AR Disputed Biomarker [217]
NCOA1 OTLIUJQD Disputed Altered Expression [218]
NEMP1 OTWN3S47 Disputed Biomarker [219]
PELI1 OTMLBCLC Disputed Biomarker [220]
PRDM6 OTKY12D9 Disputed Biomarker [220]
PRIMA1 OT9ITT3P Disputed Posttranslational Modification [221]
PSMD9 OT6Y5CC3 Disputed Biomarker [212]
RASAL1 OTAHUNN7 Disputed Biomarker [222]
SDHB OTRE1M1T Disputed Genetic Variation [223]
TCIM OTARUXQF Disputed Genetic Variation [224]
TICAM2 OTK7GIJ5 Disputed Biomarker [212]
TMED7 OTONO8E6 Disputed Biomarker [212]
TMPRSS4 OTCCGY2K Disputed Altered Expression [225]
ABCE1 OTH19LOA moderate Biomarker [226]
ABI3 OTQTDSHP moderate Posttranslational Modification [227]
ARHGEF7 OT9BPJCL moderate Altered Expression [228]
ASCC1 OTH4VAP9 moderate Altered Expression [228]
ATP5F1E OTMPLAIS moderate Altered Expression [229]
BCAM OTHZOPSD moderate Biomarker [34]
CARD11 OTRCTLYC moderate Altered Expression [230]
CCNG2 OTII38K2 moderate Biomarker [71]
CDH16 OTR0GE9G moderate Biomarker [231]
CPSF2 OTU6QXZE moderate Biomarker [232]
CRYGD OTW29JC4 moderate Genetic Variation [233]
CTDSPL OTZJ0CZK moderate Biomarker [234]
DUSP4 OT6WAO12 moderate Biomarker [235]
GNB3 OTA6HYBA moderate Genetic Variation [236]
GORASP1 OTQS91S7 moderate Posttranslational Modification [53]
GRB14 OTFET2YM moderate Altered Expression [237]
HLTF OTRX2OSF moderate Altered Expression [238]
HOXC10 OT5WF17M moderate Biomarker [239]
MSH6 OT46FP09 moderate Biomarker [240]
MT1G OTAV1OCR moderate Altered Expression [241]
NIBAN1 OTYOLI12 moderate Biomarker [242]
PA2G4 OT7IG7HT moderate Biomarker [222]
PDZK1IP1 OTWA6M5K moderate Altered Expression [243]
PPP6C OTR1STMJ moderate Biomarker [45]
RBX1 OTYA1UIO moderate Biomarker [244]
REC8 OT6JAVXE moderate Altered Expression [245]
RTN4IP1 OTHUZANE moderate Altered Expression [246]
SASH1 OTQA8BD4 moderate Biomarker [247]
SERPINA5 OTTZXPGD moderate Biomarker [235]
SLIT3 OTU8MKEU moderate Biomarker [248]
SOX17 OT9H4WWE moderate Posttranslational Modification [249]
SPC24 OT1HVYV4 moderate Altered Expression [250]
SYT1 OTVTPOI6 moderate Posttranslational Modification [53]
TBX15 OTAZ9QDX moderate Biomarker [251]
TCF7L1 OTTUTF0O moderate Biomarker [48]
TPR OTUBBA4W moderate Biomarker [48]
ABI3BP OTW8DN50 Strong Biomarker [252]
ACP1 OTJ9CKLU Strong Biomarker [253]
AFAP1L2 OTJBI0VN Strong Altered Expression [254]
AKAP9 OT7Z2YRP Strong Biomarker [255]
ANKRD36B OT3MW415 Strong Biomarker [256]
ATF1 OT251CI0 Strong Altered Expression [257]
ATF2 OTNIZPEA Strong Altered Expression [258]
BUB1B OT8KME51 Strong Biomarker [62]
C1D OTI9PMN1 Strong Biomarker [259]
CBX1 OT2L4XZX Strong Biomarker [260]
CBX5 OT8VYY84 Strong Biomarker [260]
CCDC6 OTXRQDYG Strong Genetic Variation [82]
CCDC80 OTOZSYEM Strong Biomarker [261]
CD63 OT2UGZA9 Strong Altered Expression [262]
CDC23 OTC4O83E Strong Biomarker [263]
CDH17 OT9EV2XK Strong Altered Expression [264]
CDSN OTQW4HV6 Strong Biomarker [265]
CENPJ OTZCQZN5 Strong Biomarker [266]
CITED2 OT812TV7 Strong Biomarker [267]
CLEC4D OTT7X1UC Strong Genetic Variation [60]
CORO1A OTVAZOHC Strong Altered Expression [268]
CREB3L2 OT09MHV0 Strong Genetic Variation [269]
CREB5 OTJDUJPI Strong Biomarker [270]
CRIP1 OT0EICG3 Strong Altered Expression [271]
CRIP2 OTVVJSYX Strong Biomarker [271]
DACT2 OTNLCC0K Strong Posttranslational Modification [272]
DMBT1 OTVNU9D9 Strong Altered Expression [110]
DR1 OTR081M4 Strong Biomarker [273]
DUOX2 OTU14HCN Strong Altered Expression [274]
DUSP6 OT4H6RKW Strong Biomarker [4]
ECM1 OT1K65VW Strong Altered Expression [225]
EFNB2 OT0DCUOM Strong Altered Expression [275]
ENDOU OTB7OF7Y Strong Biomarker [276]
ERRFI1 OT7VZ2IZ Strong Biomarker [277]
EXOSC6 OTAC10N6 Strong Biomarker [276]
FAM107B OT5RG4J0 Strong Altered Expression [278]
FCGBP OT63T6XQ Strong Altered Expression [279]
FGD3 OTIH6283 Strong Biomarker [280]
FGF3 OT9PK2SI Strong Biomarker [281]
FLCN OTVM78XM Strong Genetic Variation [282]
FOXA1 OTEBY0TD Strong Altered Expression [283]
FSD1 OT8P6PT3 Strong Biomarker [284]
FSD1L OTBQ48RF Strong Biomarker [284]
GADD45G OT8V1J4M Strong Biomarker [285]
GINS2 OT974IYI Strong Biomarker [267]
GOLGA5 OTG6HB6U Strong Genetic Variation [286]
GOT2 OT6XBWN0 Strong Biomarker [287]
GPLD1 OTUUQOVY Strong Altered Expression [288]
GPR68 OT1NXSMN Strong Altered Expression [289]
GYPA OTABU4YV Strong Genetic Variation [290]
HABP2 OTAUIPW0 Strong Genetic Variation [291]
HEMGN OTZPYUOY Strong Biomarker [292]
HLA-DQA2 OT1DH0N9 Strong Altered Expression [293]
HNRNPD OT5UO1FA Strong Altered Expression [294]
HNRNPF OTSMBXMF Strong Biomarker [295]
HOOK1 OTTTKV7V Strong Biomarker [296]
HOPX OTBSR6C9 Strong Altered Expression [297]
HSF2 OTXNJIJ9 Strong Biomarker [111]
ID3 OTUULW5Z Strong Altered Expression [298]
IGFBP4 OT2HZRBD Strong Biomarker [299]
INF2 OT8ZM13C Strong Biomarker [300]
INSL3 OT7KUNTE Strong Altered Expression [301]
INTS2 OT2N5TCK Strong Biomarker [281]
ITGA3 OTBCH21D Strong Biomarker [302]
IYD OT8BQWTE Strong Altered Expression [303]
KLF17 OT5NWVP7 Strong Biomarker [304]
KLLN OTV3FPH0 Strong Genetic Variation [305]
LRG1 OTLD0KWA Strong Biomarker [306]
LTBP2 OTS88GSD Strong Biomarker [307]
MADD OTUFYVGG Strong Biomarker [308]
MAPK4 OTVWWUYS Strong Altered Expression [309]
MASTL OTQ7YKK5 Strong Biomarker [310]
MIB2 OTJCC3HS Strong Biomarker [304]
MLF1 OTC5BKHU Strong Biomarker [311]
MMP20 OT16S5S3 Strong Altered Expression [312]
MMRN1 OT7ZNYHT Strong Genetic Variation [225]
MPEG1 OT7DAO0F Strong Biomarker [91]
MR1 OTZU3XX7 Strong Altered Expression [313]
MRGPRX3 OTRKCCDS Strong Genetic Variation [103]
MRGPRX4 OTOBHZVA Strong Genetic Variation [103]
MRO OT5U38CP Strong Biomarker [314]
MT1M OTVT8PLU Strong Altered Expression [315]
NAPSA OT6F8IAL Strong Biomarker [316]
ND1 OTCLGIXV Strong Genetic Variation [317]
NDRG2 OT5L6KD7 Strong Altered Expression [318]
NECTIN1 OTTE5ZR6 Strong Altered Expression [319]
NPC2 OTE9UEJC Strong Biomarker [320]
NR2F1 OTGWZWYL Strong Altered Expression [321]
NRARP OTMYHUV2 Strong Biomarker [322]
OXA1L OTS0BFRD Strong Biomarker [323]
PARP4 OTXBK59G Strong Biomarker [324]
PEA15 OTKCKTSX Strong Altered Expression [325]
PHF20 OTCBVH5P Strong Biomarker [304]
PJA2 OT45TMC4 Strong Altered Expression [326]
PPL OTTM4WDO Strong Biomarker [270]
PPP1R15A OTYG179K Strong Altered Expression [327]
PRDM2 OT8L7CGX Strong Biomarker [328]
PROK1 OT8S7RUG Strong Biomarker [329]
PROX1 OT68R6IO Strong Altered Expression [330]
PSME3 OTSTC4YY Strong Biomarker [331]
PTCH2 OTOQ0K9V Strong Biomarker [332]
PTMA OT2W4T1M Strong Biomarker [333]
PTMS OT9PS4Q0 Strong Biomarker [333]
PTPRF OTH5KF2D Strong Biomarker [50]
PTTG1 OTIMYS4W Strong Biomarker [334]
PTTG1IP OTX21QTE Strong Biomarker [334]
RAC2 OTAOHFNH Strong Altered Expression [335]
RAD52 OT0OTDHI Strong Genetic Variation [336]
RAMP1 OT7UT2XB Strong Biomarker [337]
RASIP1 OTCRY2AN Strong Altered Expression [47]
RASSF1 OTEZIPB7 Strong Posttranslational Modification [338]
RASSF10 OTGB7EBG Strong Posttranslational Modification [339]
RASSF2 OT2JHDO4 Strong Biomarker [340]
RBBP4 OTG3BT3M Strong Biomarker [341]
RCAN1 OT1MVXC7 Strong Altered Expression [342]
REV1 OTHIKICX Strong Altered Expression [343]
RGCC OTYJMLWM Strong Biomarker [263]
RLN2 OTY3OG71 Strong Altered Expression [344]
RNF139 OT0PR1X5 Strong Biomarker [345]
RPL29 OTUFIBJL Strong Altered Expression [346]
RPL36A OT1LYV85 Strong Biomarker [277]
RPS27 OTFXKY7P Strong Biomarker [91]
RREB1 OT62460U Strong Biomarker [304]
RSPO2 OT3HHXU0 Strong Altered Expression [99]
RYR2 OT0PF19E Strong Altered Expression [347]
SAGE1 OT4H6FFA Strong Biomarker [348]
SCG5 OTXSJMT1 Strong Biomarker [63]
SDC4 OTKUVUGZ Strong Biomarker [311]
SDS OT5WTJ2M Strong Genetic Variation [123]
SEC23B OT2NFSIQ Strong Genetic Variation [349]
SEC62 OTCWEL5F Strong Altered Expression [350]
SIRT4 OT5S0J23 Strong Altered Expression [351]
SIRT7 OT5M4OT4 Strong Altered Expression [352]
SLURP1 OT89YD2E Strong Genetic Variation [353]
SMG1 OTTS3SXE Strong Biomarker [354]
SMURF1 OT5UIZR8 Strong Biomarker [355]
SNAI2 OT7Y8EJ2 Strong Altered Expression [356]
SNX5 OT6ZOWMU Strong Biomarker [357]
SOD3 OTIOZQAB Strong Altered Expression [358]
SOX15 OTTB37I1 Strong Biomarker [359]
SPAG9 OT45AHMB Strong Altered Expression [360]
SSH2 OT8NCK82 Strong Altered Expression [361]
SSX2 OT2Z6RLL Strong Altered Expression [362]
ST13 OTNML6UP Strong Altered Expression [346]
STK3 OTLNSCQD Strong Biomarker [340]
STRN OTLOZL5I Strong Altered Expression [363]
TAF1 OTDYS5G4 Strong Biomarker [287]
TAS2R38 OTX5MM36 Strong Genetic Variation [82]
TCEAL4 OTX24CQI Strong Altered Expression [364]
TFF3 OTJJDRTU Strong Altered Expression [365]
TFG OT2KJENI Strong Biomarker [366]
TIMM44 OTXP7MXN Strong Genetic Variation [367]
TIMP4 OT8A68SW Strong Altered Expression [356]
TMEM184C OTCA2HUW Strong Altered Expression [368]
TMSB10 OTLVZ13T Strong Biomarker [369]
TOMM20 OT76TPR2 Strong Biomarker [370]
TRAP1 OTNG0L8J Strong Biomarker [371]
TSC2 OT47LWI9 Strong Biomarker [372]
TSPAN13 OTCS9BZY Strong Altered Expression [373]
TTF1 OT4K90WD Strong Altered Expression [316]
TTF2 OT5LJOWM Strong Biomarker [374]
ALX4 OTNS9A29 Definitive Altered Expression [375]
AMPD1 OTU17BCI Definitive Altered Expression [376]
ATF7IP OTU6ZA7F Definitive Biomarker [377]
BMP8A OT1997IN Definitive Altered Expression [378]
CAVIN2 OTFHHDRU Definitive Biomarker [379]
DEUP1 OTXLM86J Definitive Altered Expression [380]
EIF1AX OTWG2LAB Definitive Biomarker [381]
ETFA OTXX61VZ Definitive Biomarker [382]
FBLIM1 OTFHXMON Definitive Altered Expression [383]
FUCA1 OTW71IK4 Definitive Altered Expression [384]
GOPC OTRBGH71 Definitive Altered Expression [383]
HCP5 OTV0YRI8 Definitive Biomarker [385]
IGSF1 OT3XD6U2 Definitive Altered Expression [386]
INPP4B OTLROA7G Definitive Altered Expression [387]
KIF22 OTY6X6BL Definitive Biomarker [388]
KLHL14 OTYOS55H Definitive Biomarker [389]
LIMD2 OTSIFTD8 Definitive Biomarker [390]
LRIG1 OTY5HZN5 Definitive Genetic Variation [391]
MIEF1 OTFSP3FS Definitive Biomarker [392]
NOC2L OTNT7R33 Definitive Biomarker [393]
NOVA1 OT6A9KHY Definitive Biomarker [394]
OBP2A OTBIJ5TI Definitive Biomarker [388]
PATZ1 OT0X9WGR Definitive Biomarker [395]
PKHD1L1 OTREFCAA Definitive Altered Expression [396]
RAP1B OTHEIIMM Definitive Altered Expression [397]
RRS1 OTTNCZN6 Definitive Biomarker [398]
SHOC2 OTUNQ2CT Definitive Biomarker [399]
SOSTDC1 OTAKDNSM Definitive Altered Expression [189]
SPANXA1 OTMK3QIS Definitive Biomarker [400]
TFAP2B OTR1T8E9 Definitive Altered Expression [401]
TFCP2L1 OT7QIJ0X Definitive Biomarker [402]
TRIP13 OTFM3TI9 Definitive Altered Expression [403]
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⏷ Show the Full List of 318 DOT(s)

References

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89 HMGA2 Gene Expression in Fine-needle Aspiration Samples of Thyroid Nodules as a Marker for Preoperative Diagnosis of Thyroid Cancer.Appl Immunohistochem Mol Morphol. 2019 Jul;27(6):471-476. doi: 10.1097/PAI.0000000000000637.
90 Tipifarnib Inhibits HRAS-Driven Dedifferentiated Thyroid Cancers.Cancer Res. 2018 Aug 15;78(16):4642-4657. doi: 10.1158/0008-5472.CAN-17-1925. Epub 2018 May 14.
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98 BRAF(V600E)-induced KRT19 expression in thyroid cancer promotes lymph node metastasis via EMT.Oncol Lett. 2019 Jul;18(1):927-935. doi: 10.3892/ol.2019.10360. Epub 2019 May 14.
99 Upregulation of RSPO2-GPR48/LGR4 signaling in papillary thyroid carcinoma contributes to tumor progression.Oncotarget. 2017 Nov 25;8(70):114980-114994. doi: 10.18632/oncotarget.22692. eCollection 2017 Dec 29.
100 Radioiodine-Refractory Thyroid Cancer: Molecular Basis of Redifferentiation Therapies, Management, and Novel Therapies.Cancers (Basel). 2019 Sep 17;11(9):1382. doi: 10.3390/cancers11091382.
101 A Phase I Trial of the VEGF Receptor Tyrosine Kinase Inhibitor Pazopanib in Combination with the MEK Inhibitor Trametinib in Advanced Solid Tumors and Differentiated Thyroid Cancers.Clin Cancer Res. 2019 Sep 15;25(18):5475-5484. doi: 10.1158/1078-0432.CCR-18-1881. Epub 2019 Jun 11.
102 Diagnostic and prognostic value of cell-cycle regulatory genes in malignant thyroid neoplasms.World J Surg. 2006 May;30(5):767-74. doi: 10.1007/s00268-005-0308-2.
103 GPCR-mediated PI3K pathway mutations in pediatric and adult thyroid cancer.Oncotarget. 2019 Jun 25;10(41):4107-4124. doi: 10.18632/oncotarget.26993. eCollection 2019 Jun 25.
104 mTOR Pathway in Papillary Thyroid Carcinoma: Different Contributions of mTORC1 and mTORC2 Complexes for Tumor Behavior and SLC5A5 mRNA Expression.Int J Mol Sci. 2018 May 13;19(5):1448. doi: 10.3390/ijms19051448.
105 Thyroid cancer susceptibility and THRA1 and BAT-40 repeats polymorphisms.Cancer Epidemiol Biomarkers Prev. 2005 Mar;14(3):638-42. doi: 10.1158/1055-9965.EPI-04-0424.
106 TERT, BRAF, and NRAS in Primary Thyroid Cancer and Metastatic Disease.J Clin Endocrinol Metab. 2017 Jun 1;102(6):1898-1907. doi: 10.1210/jc.2016-2785.
107 NRG1 regulates redox homeostasis via NRF2 in papillary thyroid cancer.Int J Oncol. 2018 Aug;53(2):685-693. doi: 10.3892/ijo.2018.4426. Epub 2018 May 31.
108 Growth inhibition of thyroid follicular cell-derived cancers by the opioid growth factor (OGF) - opioid growth factor receptor (OGFr) axis.BMC Cancer. 2009 Oct 18;9:369. doi: 10.1186/1471-2407-9-369.
109 Human peptidylglycine alpha-amidating monooxygenase: cDNA, cloning and functional expression of a truncated form in COS cells.Biochem Biophys Res Commun. 1990 Jun 15;169(2):551-8. doi: 10.1016/0006-291x(90)90366-u.
110 Expression of PDK-1 and DMBT1 in the thyroid carcinoma and its clinicopathological significance.Oncol Lett. 2019 Sep;18(3):2819-2824. doi: 10.3892/ol.2019.10639. Epub 2019 Jul 18.
111 E2F, HSF2, and miR-26 in thyroid carcinoma: bioinformatic analysis of RNA-sequencing data.Genet Mol Res. 2016 Mar 11;15(1):15017576. doi: 10.4238/gmr.15017576.
112 Senescent thyrocytes and thyroid tumor cells induce M2-like macrophage polarization of human monocytes via a PGE2-dependent mechanism.J Exp Clin Cancer Res. 2019 May 21;38(1):208. doi: 10.1186/s13046-019-1198-8.
113 The tyrosine phosphatase PTPRJ/DEP-1 genotype affects thyroid carcinogenesis.Oncogene. 2004 Nov 4;23(52):8432-8. doi: 10.1038/sj.onc.1207766.
114 Family of microRNA-146 Regulates RAR in Papillary Thyroid Carcinoma.PLoS One. 2016 Mar 24;11(3):e0151968. doi: 10.1371/journal.pone.0151968. eCollection 2016.
115 Genome-wide gene expression profiles of thyroid carcinoma: Identification of molecular targets for treatment of thyroid carcinoma.Oncol Rep. 2008 Jul;20(1):105-21.
116 Tc-99m HYNIC-TOC scintigraphy in dedifferentiated thyroid cancer.BMJ Case Rep. 2019 Apr 1;12(4):e227910. doi: 10.1136/bcr-2018-227910.
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132 Effect of low-dose tungsten on human thyroid stem/precursor cells and their progeny.Endocr Relat Cancer. 2019 Aug;26(8):713-725. doi: 10.1530/ERC-19-0176.
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134 Targeting Novel Sodium Iodide Symporter Interactors ADP-Ribosylation Factor 4 and Valosin-Containing Protein Enhances Radioiodine Uptake.Cancer Res. 2020 Jan 1;80(1):102-115. doi: 10.1158/0008-5472.CAN-19-1957. Epub 2019 Oct 31.
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136 Role of chemokine receptors in thyroid cancer and immunotherapy.Endocr Relat Cancer. 2019 Aug;26(8):R465-R478. doi: 10.1530/ERC-19-0163.
137 The HuR CMLD-2 inhibitor exhibits antitumor effects via MAD2 downregulation in thyroid cancer cells.Sci Rep. 2019 May 14;9(1):7374. doi: 10.1038/s41598-019-43894-0.
138 Neovascular PSMA expression is a common feature in malignant neoplasms of the thyroid.Oncotarget. 2018 Jan 4;9(11):9867-9874. doi: 10.18632/oncotarget.23984. eCollection 2018 Feb 9.
139 Growth-associated protein 43 promotes thyroid cancer cell lines progression via epithelial-mesenchymal transition.J Cell Mol Med. 2019 Dec;23(12):7974-7984. doi: 10.1111/jcmm.14460. Epub 2019 Sep 30.
140 IL13RA2 Is Differentially Regulated in Papillary Thyroid Carcinoma vs Follicular Thyroid Carcinoma.J Clin Endocrinol Metab. 2019 Nov 1;104(11):5573-5584. doi: 10.1210/jc.2019-00040.
141 MAPK- and AKT-activated thyroid cancers are sensitive to group I PAK inhibition.Endocr Relat Cancer. 2019 Aug;26(8):699-712. doi: 10.1530/ERC-19-0188.
142 Activation of AMPK promotes thyroid cancer cell migration through its interaction with PKM2 and -catenin.Life Sci. 2019 Dec 15;239:116877. doi: 10.1016/j.lfs.2019.116877. Epub 2019 Oct 25.
143 The role of Slit2 as a tumor suppressor in thyroid cancer.Mol Cell Endocrinol. 2019 Mar 1;483:87-96. doi: 10.1016/j.mce.2019.01.010. Epub 2019 Jan 12.
144 Differential regulation of monocarboxylate transporter 8 expression in thyroid cancer and hyperthyroidism.Eur J Endocrinol. 2017 Sep;177(3):243-250. doi: 10.1530/EJE-17-0279. Epub 2017 Jun 2.
145 RAGE Mediates the Pro-Migratory Response of Extracellular S100A4 in Human Thyroid Cancer Cells.Thyroid. 2015 May;25(5):514-27. doi: 10.1089/thy.2014.0257. Epub 2015 Apr 3.
146 Effect of perioperative treatment with a hypoxia-inducible factor-1-alpha inhibitor in an orthotopic surgical mouse model of thyroid cancer.Anticancer Res. 2015 Apr;35(4):2049-54.
147 Circulating tumour DNA is a potential biomarker for disease progression and response to targeted therapy in advanced thyroid cancer.Eur J Cancer. 2018 Nov;103:165-175. doi: 10.1016/j.ejca.2018.08.013. Epub 2018 Sep 22.
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149 Indomethacin, a cox inhibitor, enhances 15-PGDH and decreases human tumoral C cells proliferation.Prostaglandins Other Lipid Mediat. 2001 May;65(1):11-20. doi: 10.1016/s0090-6980(01)00116-2.
150 Uridine phosphorylase 1 associates to biological and clinical significance in thyroid carcinoma cell lines.J Cell Mol Med. 2019 Nov;23(11):7438-7448. doi: 10.1111/jcmm.14612. Epub 2019 Sep 9.
151 Gene Expression of CYP1A1 and its Possible Clinical Application in Thyroid Cancer Cases.Asian Pac J Cancer Prev. 2016;17(7):3477-82.
152 Haplotype analysis of XRCC1 gene polymorphisms and the risk of thyroid carcinoma.J BUON. 2018 Jan-Feb;23(1):234-243.
153 Glutathione S-transferase M1, T1, and P1 polymorphisms and thyroid cancer risk: a meta-analysis.Cancer Epidemiol. 2012 Dec;36(6):e333-40. doi: 10.1016/j.canep.2012.06.002. Epub 2012 Jul 4.
154 Activation of nicotinamide N-methyltransferase gene promoter by hepatocyte nuclear factor-1beta in human papillary thyroid cancer cells.Mol Endocrinol. 2005 Feb;19(2):527-39. doi: 10.1210/me.2004-0215. Epub 2004 Oct 14.
155 Up-Regulated AKR1C2 is correlated with favorable prognosis in thyroid carcinoma.J Cancer. 2019 Jun 9;10(15):3543-3552. doi: 10.7150/jca.28364. eCollection 2019.
156 Afamin promotes glucose metabolism in papillary thyroid carcinoma.Mol Cell Endocrinol. 2016 Oct 15;434:108-15. doi: 10.1016/j.mce.2016.06.013. Epub 2016 Jun 18.
157 Effect of alkylglycerone phosphate synthase on the expression profile of circRNAs in the human thyroid cancer cell line FRO.Oncol Lett. 2018 May;15(5):7889-7899. doi: 10.3892/ol.2018.8356. Epub 2018 Mar 26.
158 Silencing of A-Kinase Anchor Protein 4 (AKAP4) Inhibits Proliferation and Progression of Thyroid Cancer.Oncol Res. 2017 Jul 5;25(6):873-878. doi: 10.3727/096504016X14783701102564. Epub 2016 Nov 8.
159 Dysadherin specific drug conjugates for the treatment of thyroid cancers with aggressive phenotypes.Oncotarget. 2017 Apr 11;8(15):24457-24468. doi: 10.18632/oncotarget.14904.
160 Anoctamin5 regulates cell migration and invasion in thyroid cancer.Int J Oncol. 2017 Oct;51(4):1311-1319. doi: 10.3892/ijo.2017.4113. Epub 2017 Sep 1.
161 Comprehensive analysis of the clinical significance and prospective molecular mechanisms of differentially expressed autophagy-related genes in thyroid cancer.Int J Oncol. 2018 Aug;53(2):603-619. doi: 10.3892/ijo.2018.4404. Epub 2018 May 11.
162 The anti-apoptotic BAG3 protein is involved in BRAF inhibitor resistance in melanoma cells.Oncotarget. 2017 Jun 30;8(46):80393-80404. doi: 10.18632/oncotarget.18902. eCollection 2017 Oct 6.
163 Restoration of Brain Acid Soluble Protein 1 Inhibits Proliferation and Migration of Thyroid Cancer Cells.Chin Med J (Engl). 2016 Jun 20;129(12):1439-46. doi: 10.4103/0366-6999.183434.
164 The bHLH transcription factor DEC1 promotes thyroid cancer aggressiveness by the interplay with NOTCH1.Cell Death Dis. 2018 Aug 29;9(9):871. doi: 10.1038/s41419-018-0933-y.
165 Identification of Novel Oncogenic Mutations inThyroid Cancer.J Am Coll Surg. 2016 Jun;222(6):1036-1043.e2. doi: 10.1016/j.jamcollsurg.2015.12.047. Epub 2016 Jan 14.
166 Iodine-131 treatment of thyroid cancer cells leads to suppression of cell proliferation followed by induction of cell apoptosis and cell cycle arrest by regulation of B-cell translocation gene 2-mediated JNK/NF-B pathways.Braz J Med Biol Res. 2017 Jan 16;50(1):e5933. doi: 10.1590/1414-431X20165933.
167 C14orf93 (RTFC) is identified as a novel susceptibility gene for familial nonmedullary thyroid cancer.Biochem Biophys Res Commun. 2017 Jan 22;482(4):590-596. doi: 10.1016/j.bbrc.2016.11.078. Epub 2016 Nov 15.
168 Role of Chemokines in Thyroid Cancer Microenvironment: Is CXCL8 the Main Player?.Front Endocrinol (Lausanne). 2018 Jun 21;9:314. doi: 10.3389/fendo.2018.00314. eCollection 2018.
169 CITED1 gene promotes proliferation, migration and invasion in papillary thyroid cancer.Oncol Lett. 2018 Jul;16(1):105-112. doi: 10.3892/ol.2018.8653. Epub 2018 May 7.
170 Targeting COPZ1 non-oncogene addiction counteracts the viability of thyroid tumor cells.Cancer Lett. 2017 Dec 1;410:201-211. doi: 10.1016/j.canlet.2017.09.024. Epub 2017 Sep 23.
171 Increased expression of EHF contributes to thyroid tumorigenesis through transcriptionally regulating HER2 and HER3.Oncotarget. 2016 Sep 6;7(36):57978-57990. doi: 10.18632/oncotarget.11154.
172 Relationship of Focally Amplified Long Noncoding on Chromosome 1 (FAL1) lncRNA with E2F Transcription Factors in Thyroid Cancer.Medicine (Baltimore). 2016 Jan;95(4):e2592. doi: 10.1097/MD.0000000000002592.
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174 An integrated analysis of cancer genes in thyroid cancer.Oncol Rep. 2016 Feb;35(2):962-70. doi: 10.3892/or.2015.4466. Epub 2015 Dec 1.
175 Emerging roles of circRNA_NEK6 targeting miR-370-3p in the proliferation and invasion of thyroid cancer via Wnt signaling pathway.Cancer Biol Ther. 2018;19(12):1139-1152. doi: 10.1080/15384047.2018.1480888. Epub 2018 Sep 12.
176 Knockdown of GATAD2A suppresses cell proliferation in thyroid cancer invitro.Oncol Rep. 2017 Apr;37(4):2147-2152. doi: 10.3892/or.2017.5436. Epub 2017 Feb 10.
177 Elevated HMGN4 expression potentiates thyroid tumorigenesis.Carcinogenesis. 2017 Apr 1;38(4):391-401. doi: 10.1093/carcin/bgx015.
178 HORMAD2 methylation-mediated epigenetic regulation of gene expression in thyroid cancer.J Cell Mol Med. 2018 Oct;22(10):4640-4652. doi: 10.1111/jcmm.13680. Epub 2018 Jul 24.
179 Tumour suppressive function of HUWE1 in thyroid cancer.J Biosci. 2016 Sep;41(3):395-405. doi: 10.1007/s12038-016-9623-z.
180 Loss-of-function of IFT88 determines metabolic phenotypes in thyroid cancer.Oncogene. 2018 Aug;37(32):4455-4474. doi: 10.1038/s41388-018-0211-6. Epub 2018 May 10.
181 THADA fusion is a mechanism of IGF2BP3 activation and IGF1R signaling in thyroid cancer.Proc Natl Acad Sci U S A. 2017 Feb 28;114(9):2307-2312. doi: 10.1073/pnas.1614265114. Epub 2017 Feb 13.
182 IL-17RB enhances thyroid cancer cell invasion and metastasis via ERK1/2 pathway-mediated MMP-9 expression.Mol Immunol. 2017 Oct;90:126-135. doi: 10.1016/j.molimm.2017.06.034. Epub 2017 Jul 15.
183 Overexpression of ING5 inhibits HGF-induced proliferation, invasion and EMT in thyroid cancer cells via regulation of the c-Met/PI3K/Akt signaling pathway.Biomed Pharmacother. 2018 Feb;98:265-270. doi: 10.1016/j.biopha.2017.12.045. Epub 2017 Dec 27.
184 Activating KIR2DS5 receptor is a risk for thyroid cancer.Hum Immunol. 2012 Oct;73(10):1017-22. doi: 10.1016/j.humimm.2012.07.325. Epub 2012 Jul 23.
185 Coupling of LETM1 up-regulation with oxidative phosphorylation and platelet-derived growth factor receptor signaling via YAP1 transactivation.Oncotarget. 2016 Oct 11;7(41):66728-66739. doi: 10.18632/oncotarget.11456.
186 LRP4 promotes proliferation, migration, and invasion in papillary thyroid cancer.Biochem Biophys Res Commun. 2018 Sep 3;503(1):257-263. doi: 10.1016/j.bbrc.2018.06.012. Epub 2018 Jun 11.
187 MREG suppresses thyroid cancer cell invasion and proliferation by inhibiting Akt-mTOR signaling.Biochem Biophys Res Commun. 2017 Sep 9;491(1):72-78. doi: 10.1016/j.bbrc.2017.07.044. Epub 2017 Jul 8.
188 A novel tumor suppressor gene NCOA5 is correlated with progression in papillary thyroid carcinoma.Onco Targets Ther. 2018 Jan 11;11:307-311. doi: 10.2147/OTT.S154158. eCollection 2018.
189 E4BP4 promotes thyroid cancer proliferation by modulating iron homeostasis through repression of hepcidin.Cell Death Dis. 2018 Sep 24;9(10):987. doi: 10.1038/s41419-018-1001-3.
190 Positive Feedback Loops Between NrCAM and Major Signaling Pathways Contribute to Thyroid Tumorigenesis.J Clin Endocrinol Metab. 2017 Feb 1;102(2):613-624. doi: 10.1210/jc.2016-1677.
191 Low dose radiation regulates BRAF-induced thyroid cellular dysfunction and transformation.Cell Commun Signal. 2019 Feb 13;17(1):12. doi: 10.1186/s12964-019-0322-x.
192 Poly r(C) binding protein (PCBP) 1 expression is regulated at the post-translation level in thyroid carcinoma.Am J Transl Res. 2017 Feb 15;9(2):708-714. eCollection 2017.
193 Therapeutic effects of adenovirus-mediated CD and NIS expression combined with Na(131)I/5-FC on human thyroid cancer.Oncol Lett. 2017 Dec;14(6):7431-7436. doi: 10.3892/ol.2017.7175. Epub 2017 Oct 12.
194 Differential expression of PIWIL2 in papillary thyroid cancers.Gene. 2018 Apr 5;649:8-13. doi: 10.1016/j.gene.2018.01.066. Epub 2018 Jan 31.
195 A new POT1 germline mutation-expanding the spectrum of POT1-associated cancers.Fam Cancer. 2017 Oct;16(4):561-566. doi: 10.1007/s10689-017-9984-y.
196 The common genetic variant rs944289 on chromosome 14q13.3 associates with risk of both malignant and benign thyroid tumors in the Japanese population.Thyroid. 2015 Mar;25(3):333-40. doi: 10.1089/thy.2014.0431. Epub 2015 Feb 5.
197 MiR-150 Inhibits Cell Growth In Vitro and In Vivo by Restraining the RAB11A/WNT/-Catenin Pathway in Thyroid Cancer.Med Sci Monit. 2017 Oct 12;23:4885-4894. doi: 10.12659/msm.906997.
198 Vemurafenib-resistance via de novo RBM genes mutations and chromosome 5 aberrations is overcome by combined therapy with palbociclib in thyroid carcinoma with BRAF(V600E).Oncotarget. 2017 Sep 24;8(49):84743-84760. doi: 10.18632/oncotarget.21262. eCollection 2017 Oct 17.
199 Immunohistochemical expression of RBP2 and LSD1 in papillary thyroid carcinoma.Rom J Morphol Embryol. 2013;54(3):499-503.
200 A somatic mutation of RasGRP3 decreases Na(+)/I(-) symporter expression in metastases of radioactive iodine-refractory thyroid cancer by stimulating the Akt signaling pathway.Am J Cancer Res. 2018 Sep 1;8(9):1847-1855. eCollection 2018.
201 Analysis of ribonuclease activity in sub-nanoliter droplets by label-free fluorescence measurements.Analyst. 2017 Jul 10;142(14):2610-2616. doi: 10.1039/c6an02724e.
202 Solute carrier family 35 member F2 is indispensable for papillary thyroid carcinoma progression through activation of transforming growth factor- type I receptor/apoptosis signal-regulating kinase 1/mitogen-activated protein kinase signaling axis.Cancer Sci. 2018 Mar;109(3):642-655. doi: 10.1111/cas.13478. Epub 2018 Feb 1.
203 LncRNA SPRY4-IT was concerned with the poor prognosis and contributed to the progression of thyroid cancer.Cancer Gene Ther. 2018 Feb;25(1-2):39-46. doi: 10.1038/s41417-017-0003-0. Epub 2017 Dec 12.
204 HABP2 germline variants are uncommon in familial nonmedullary thyroid cancer.BMC Med Genet. 2016 Aug 17;17(1):60. doi: 10.1186/s12881-016-0323-1.
205 An epistatic interaction between the PAX8 and STK17B genes in papillary thyroid cancer susceptibility.PLoS One. 2013 Sep 23;8(9):e74765. doi: 10.1371/journal.pone.0074765. eCollection 2013.
206 Effect of Interferon- on the Basal and the TNF-Stimulated Secretion of CXCL8 in Thyroid Cancer Cell Lines Bearing Either the RET/PTC Rearrangement Or the BRAF V600e Mutation.Mediators Inflamm. 2016;2016:8512417. doi: 10.1155/2016/8512417. Epub 2016 Jul 31.
207 Silencing of TCTN1 inhibits proliferation, induces cell cycle arrest and apoptosis in human thyroid cancer.Exp Ther Med. 2017 Oct;14(4):3720-3726. doi: 10.3892/etm.2017.4940. Epub 2017 Aug 16.
208 Long non-coding RNA NEAT1 promotes malignant progression of thyroid carcinoma by regulating miRNA-214.Int J Oncol. 2017 Feb;50(2):708-716. doi: 10.3892/ijo.2016.3803. Epub 2016 Dec 14.
209 TRIM29 promotes progression of thyroid carcinoma via activating P13K/AKT signaling pathway.Oncol Rep. 2017 Mar;37(3):1555-1564. doi: 10.3892/or.2017.5364. Epub 2017 Jan 13.
210 Knockdown of TRIM44 inhibits the proliferation and invasion in papillary thyroid cancer cells through suppressing the Wnt/-catenin signaling pathway.Biomed Pharmacother. 2017 Dec;96:98-103. doi: 10.1016/j.biopha.2017.09.132. Epub 2017 Sep 29.
211 CD97 amplifies LPA receptor signaling and promotes thyroid cancer progression in a mouse model.Oncogene. 2013 May 30;32(22):2726-38. doi: 10.1038/onc.2012.301. Epub 2012 Jul 16.
212 Rewiring of the apoptotic TGF--SMAD/NFB pathway through an oncogenic function of p27 in human papillary thyroid cancer.Oncogene. 2017 Feb 2;36(5):652-666. doi: 10.1038/onc.2016.233. Epub 2016 Jul 25.
213 A nested case-control study of polychlorinated biphenyls, organochlorine pesticides, and thyroid cancer in the Janus Serum Bank cohort.Environ Res. 2018 Aug;165:125-132. doi: 10.1016/j.envres.2018.04.012. Epub 2018 Apr 23.
214 FOXE1 regulates migration and invasion in thyroid cancer cells and targets ZEB1.Endocr Relat Cancer. 2020 Mar;27(3):137-151. doi: 10.1530/ERC-19-0156.
215 Metformin Targets Mitochondrial Glycerophosphate Dehydrogenase to Control Rate of Oxidative Phosphorylation and Growth of Thyroid Cancer In Vitro and In Vivo.Clin Cancer Res. 2018 Aug 15;24(16):4030-4043. doi: 10.1158/1078-0432.CCR-17-3167. Epub 2018 Apr 24.
216 Knockdown of IQGAP1 inhibits proliferation and epithelial-mesenchymal transition by Wnt/-catenin pathway in thyroid cancer.Onco Targets Ther. 2017 Mar 13;10:1549-1559. doi: 10.2147/OTT.S128564. eCollection 2017.
217 Mutant MYO1F alters the mitochondrial network and induces tumor proliferation in thyroid cancer.Int J Cancer. 2018 Oct 1;143(7):1706-1719. doi: 10.1002/ijc.31548. Epub 2018 May 7.
218 Steroid receptor coactivator-1 interacts with NF-B to increase VEGFC levels in human thyroid cancer.Biosci Rep. 2018 Jun 12;38(3):BSR20180394. doi: 10.1042/BSR20180394. Print 2018 Jun 29.
219 Gene master regulators of papillary and anaplastic thyroid cancers.Oncotarget. 2017 Dec 19;9(2):2410-2424. doi: 10.18632/oncotarget.23417. eCollection 2018 Jan 5.
220 Pictorial Representation of Illness and Self Measure-Revised 2 (PRISM-R2): an effective tool to assess perceived burden of thyroid cancer in mainland China.Support Care Cancer. 2018 Sep;26(9):3267-3275. doi: 10.1007/s00520-018-4172-7. Epub 2018 Apr 11.
221 PRIMA-1 selectively induces global DNA demethylation in p53 mutant-type thyroid cancer cells.J Biomed Nanotechnol. 2014 Jul;10(7):1249-58. doi: 10.1166/jbn.2014.1862.
222 EBP1 suppresses growth, migration, and invasion of thyroid cancer cells through upregulating RASAL expression.Tumour Biol. 2015 Nov;36(11):8325-31. doi: 10.1007/s13277-015-3523-y. Epub 2015 May 26.
223 Germline and somatic SDHx alterations in apparently sporadic differentiated thyroid cancer.Endocr Relat Cancer. 2015 Apr;22(2):121-30. doi: 10.1530/ERC-14-0537.
224 The high expression of TC1 (C8orf4) was correlated with the expression of -catenin and cyclin D1 and the progression of squamous cell carcinomas of the tongue.Tumour Biol. 2015 Sep;36(9):7061-7. doi: 10.1007/s13277-015-3423-1. Epub 2015 Apr 14.
225 Vitamin D receptor expression is linked to potential markers of human thyroid papillary carcinoma.J Steroid Biochem Mol Biol. 2016 May;159:26-30. doi: 10.1016/j.jsbmb.2016.02.016. Epub 2016 Feb 22.
226 Effect of ABCE1-silencing gene, transfected by electrotransfer, on the proliferation, invasion, and migration of human thyroid carcinoma SW579 cells.Genet Mol Res. 2015 Nov 23;14(4):14680-9. doi: 10.4238/2015.November.18.32.
227 Transcriptional regulation of the potential tumor suppressor ABI3 gene in thyroid carcinomas: interplay between methylation and NKX2-1 availability.Oncotarget. 2016 May 3;7(18):25960-70. doi: 10.18632/oncotarget.8416.
228 The levels of NF-B p50 and NF-B p65 play a role in thyroid carcinoma malignancy in vivo.J Int Med Res. 2018 Oct;46(10):4092-4099. doi: 10.1177/0300060518785846. Epub 2018 Jul 17.
229 Molecular Analysis by Gene Expression of Mitochondrial ATPase Subunits in Papillary Thyroid Cancer: Is ATP5E Transcript a Possible Early Tumor Marker?.Med Sci Monit. 2015 Jun 16;21:1745-51. doi: 10.12659/MSM.893597.
230 MiR-539 inhibits thyroid cancer cell migration and invasion by directly targeting CARMA1.Biochem Biophys Res Commun. 2015 Sep 4;464(4):1128-1133. doi: 10.1016/j.bbrc.2015.07.090. Epub 2015 Jul 20.
231 CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas.Endocrinology. 2012 Jan;153(1):522-34. doi: 10.1210/en.2011-1572. Epub 2011 Oct 25.
232 Loss of CPSF2 expression is associated with increased thyroid cancer cellular invasion and cancer stem cell population, and more aggressive disease.J Clin Endocrinol Metab. 2014 Jul;99(7):E1173-82. doi: 10.1210/jc.2013-4140. Epub 2014 Mar 21.
233 X-ray repair cross-complementing group 1(XRCC1) genetic polymorphisms and thyroid carcinoma risk: a meta-analysis.Asian Pac J Cancer Prev. 2012;13(12):6385-90. doi: 10.7314/apjcp.2012.13.12.6385.
234 Expression of miR-100 and RBSP3 in FTC-133 cells after exposure to 131I.Nucl Med Commun. 2014 Sep;35(9):932-8. doi: 10.1097/MNM.0000000000000142.
235 DNA methylation of MAPK signal-inhibiting genes in papillary thyroid carcinoma.Anticancer Res. 2013 Nov;33(11):4833-9.
236 Quantitative assessment of the association between GNB3 C825T polymorphism and cancer risk.J BUON. 2014 Oct-Dec;19(4):1092-5.
237 The insulin resistance Grb14 adaptor protein promotes thyroid cancer ret signaling and progression.Oncogene. 2012 Sep 6;31(36):4012-21. doi: 10.1038/onc.2011.569. Epub 2011 Dec 12.
238 Helicase-like transcription factor: a new marker of well-differentiated thyroid cancers.BMC Cancer. 2014 Jul 8;14:492. doi: 10.1186/1471-2407-14-492.
239 HOXC10 up-regulation contributes to human thyroid cancer and indicates poor survival outcome.Mol Biosyst. 2015 Nov;11(11):2946-54. doi: 10.1039/c5mb00253b.
240 Mismatch repair single nucleotide polymorphisms and thyroid cancer susceptibility.Oncol Lett. 2018 May;15(5):6715-6726. doi: 10.3892/ol.2018.8103. Epub 2018 Feb 21.
241 Metallothionein 1G functions as a tumor suppressor in thyroid cancer through modulating the PI3K/Akt signaling pathway.BMC Cancer. 2013 Oct 8;13:462. doi: 10.1186/1471-2407-13-462.
242 FAM129A regulates autophagy in thyroid carcinomas in an oncogene-dependent manner.Endocr Relat Cancer. 2019 Jan 1;26(1):227-238. doi: 10.1530/ERC-17-0530.
243 Identification of targets of Twist1 transcription factor in thyroid cancer cells.J Clin Endocrinol Metab. 2014 Sep;99(9):E1617-26. doi: 10.1210/jc.2013-3799. Epub 2014 May 21.
244 Frequent concerted genetic mechanisms disrupt multiple components of the NRF2 inhibitor KEAP1/CUL3/RBX1 E3-ubiquitin ligase complex in thyroid cancer.Mol Cancer. 2013 Oct 20;12(1):124. doi: 10.1186/1476-4598-12-124.
245 REC8 is a novel tumor suppressor gene epigenetically robustly targeted by the PI3K pathway in thyroid cancer.Oncotarget. 2015 Nov 17;6(36):39211-24. doi: 10.18632/oncotarget.5391.
246 RTN4IP1 is down-regulated in thyroid cancer and has tumor-suppressive function.J Clin Endocrinol Metab. 2013 Mar;98(3):E446-54. doi: 10.1210/jc.2012-3180. Epub 2013 Feb 7.
247 SASH1 inhibits proliferation and invasion of thyroid cancer cells through PI3K/Akt signaling pathway.Int J Clin Exp Pathol. 2015 Oct 1;8(10):12276-83. eCollection 2015.
248 Down-regulation of miR-218-2 and its host gene SLIT3 cooperate to promote invasion and progression of thyroid cancer.J Clin Endocrinol Metab. 2013 Aug;98(8):E1334-44. doi: 10.1210/jc.2013-1053. Epub 2013 May 29.
249 Epigenetic regulation of Wnt signaling pathway gene SRY-related HMG-box 17 in papillary thyroid carcinoma.Chin Med J (Engl). 2012 Oct;125(19):3526-31.
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389 A ceRNA Circuitry Involving the Long Noncoding RNA Klhl14-AS, Pax8, and Bcl2 Drives Thyroid Carcinogenesis.Cancer Res. 2019 Nov 15;79(22):5746-5757. doi: 10.1158/0008-5472.CAN-19-0039. Epub 2019 Sep 26.
390 LIMD2 targeted by miR?4a promotes the proliferation and invasion of nonsmall cell lung cancer cells.Mol Med Rep. 2018 Nov;18(5):4760-4766. doi: 10.3892/mmr.2018.9464. Epub 2018 Sep 6.
391 LRIG1 negatively regulates RET mutants and is downregulated in thyroid cancer.Int J Oncol. 2018 Apr;52(4):1189-1197. doi: 10.3892/ijo.2018.4273. Epub 2018 Feb 9.
392 Mst1 overexpression combined with Yap knockdown augments thyroid carcinoma apoptosis via promoting MIEF1-related mitochondrial fission and activating the JNK pathway.Cancer Cell Int. 2019 May 22;19:143. doi: 10.1186/s12935-019-0860-8. eCollection 2019.
393 Novel design of NIR-triggered plasmonic nanodots capped mesoporous silica nanoparticles loaded with natural capsaicin to inhibition of metastasis of human papillary thyroid carcinoma B-CPAP cells in thyroid cancer chemo-photothermal therapy.J Photochem Photobiol B. 2019 Aug;197:111534. doi: 10.1016/j.jphotobiol.2019.111534. Epub 2019 Jun 15.
394 MicroRNA-592 suppresses the malignant phenotypes of thyroid cancer by regulating lncRNA NEAT1 and downregulating NOVA1.Int J Mol Med. 2019 Sep;44(3):1172-1182. doi: 10.3892/ijmm.2019.4278. Epub 2019 Jul 16.
395 Loss of One or Two PATZ1 Alleles Has a Critical Role in the Progression of Thyroid Carcinomas Induced by the RET/PTC1 Oncogene.Cancers (Basel). 2018 Mar 27;10(4):92. doi: 10.3390/cancers10040092.
396 Original tumour suppressor gene polycystic kidney and hepatic disease 1-like 1 is associated with thyroid cancer cell progression.Oncol Lett. 2019 Sep;18(3):3227-3235. doi: 10.3892/ol.2019.10632. Epub 2019 Jul 18.
397 miR-206 inhibits thyroid cancer proliferation and invasion by targeting RAP1B.J Cell Biochem. 2019 Nov;120(11):18927-18936. doi: 10.1002/jcb.29213. Epub 2019 Jun 27.
398 RRS1 gene expression involved in the progression of papillary thyroid carcinoma.Cancer Cell Int. 2018 Feb 13;18:20. doi: 10.1186/s12935-018-0519-x. eCollection 2018.
399 MiR-299-3p functions as a tumor suppressor in thyroid cancer by regulating SHOC2.Eur Rev Med Pharmacol Sci. 2019 Jan;23(1):232-240. doi: 10.26355/eurrev_201901_16769.
400 Iodine promotes thyroid cancer development via SPANXA1 through the PI3K/AKT signalling pathway.Oncol Lett. 2019 Jul;18(1):637-644. doi: 10.3892/ol.2019.10391. Epub 2019 May 21.
401 TFAP2B overexpression contributes to tumor growth and progression of thyroid cancer through the COX-2 signaling pathway.Cell Death Dis. 2019 May 21;10(6):397. doi: 10.1038/s41419-019-1600-7.
402 TFCP2/TFCP2L1/UBP1 transcription factors in cancer.Cancer Lett. 2018 Apr 28;420:72-79. doi: 10.1016/j.canlet.2018.01.078. Epub 2018 Feb 7.
403 TRIP13 interference inhibits the proliferation and metastasis of thyroid cancer cells through regulating TTC5/p53 pathway and epithelial-mesenchymal transition related genes expression.Biomed Pharmacother. 2019 Dec;120:109508. doi: 10.1016/j.biopha.2019.109508. Epub 2019 Oct 22.