Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DM5TVS3)

Drug Name
Vinblastine Drug Info
Synonyms
Nincaluicolflastine; Rozevin; VLB; Vinblastin; Vinblastina; Vinblastinum; Vincaleucoblastin; Vincaleucoblastine; Vincaleukoblastine; Vincoblastine; Vinblastina [DCIT]; VR-8; Vinblastina (TN); Vinblastine (INN); Vinblastine [INN:BAN]; Vinblastinum [INN-Latin]; NDC 0002-1452-01; (2ALPHA,2'BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE; (2xi,3beta,4'beta,19xi)-vincaleukoblastine; 1H-Indolizino(8,1-cd)carbazole-5-carboxylic acid
Indication
Disease Entry ICD 11 Status REF
Advanced cancer 2A00-2F9Z Approved [1]
Anterior urethra cancer Approved [1]
Extragonadal germ cell tumor Approved [1]
Gestational trophoblastic neoplasia 2F33-2F76 Approved [1]
Kaposi sarcoma 2B57 Approved [1]
Mycosis fungoides 2B01 Approved [1]
Posterior urethra cancer Approved [1]
Solid tumour/cancer 2A00-2F9Z Approved [2]
Testicular cancer 2C80 Approved [1]
Testicular germ cell tumor Approved [1]
Classic Hodgkin lymphoma Investigative [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
13342
CAS Number
CAS 865-21-4
TTD Drug ID
DM5TVS3
VARIDT Drug ID
DR00308
INTEDE Drug ID
DR1689

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Clinical Trial Drug(s)
Investigative Drug(s)
Approved Drug(s)
Preclinical Drug(s)
Patented Agent(s)
Download the Complete Related Drug List
Drug(s) Targeting Tubulin beta-2 chain (TUBB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DOLASTATIN-10 DMDUV1S Solid tumour/cancer 2A00-2F9Z Phase 2 [15]
3-bromo-4,4',5-trimethoxy-(Z)-stilbene DMPZ4M8 Discovery agent N.A. Investigative [16]
6-ile-ustiloxin DMQF8JG Discovery agent N.A. Investigative [15]
3,4',5-trimethoxy-(Z)-stilbene DMYHC3S Discovery agent N.A. Investigative [16]
Ustiloxin D DMA8JH7 Discovery agent N.A. Investigative [15]
Ustiloxin F DMT1LS0 Discovery agent N.A. Investigative [15]
3,4,4',5-tetramethoxy-(Z)-stilbene DMSN814 Discovery agent N.A. Investigative [16]
2,3'-diamino-3,4,4',5-tetramethoxy-(Z)-stillbene DM2UWDR Discovery agent N.A. Investigative [16]
USTILOXIN A DMZP32O Discovery agent N.A. Investigative [15]
N-(4-(3-(pyridin-2-yl)acryloyl)phenyl)acetamide DMRH987 Discovery agent N.A. Investigative [17]
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Drug(s) Transported By Multidrug resistance-associated protein 1 (ABCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [18]
Methotrexate DM2TEOL Anterior urethra cancer Approved [19]
Folic Acid DMEMBJC Colorectal carcinoma Approved [20]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [21]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [23]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [24]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [25]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [26]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [27]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [78]
Folic Acid DMEMBJC Colorectal carcinoma Approved [20]
Methotrexate DM2TEOL Anterior urethra cancer Approved [79]
Quercetin DM3NC4M Obesity 5B81 Approved [80]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [81]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [82]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [84]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [85]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [85]
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Drug(s) Transported By Multidrug resistance-associated protein 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [28]
Methotrexate DM2TEOL Anterior urethra cancer Approved [29]
Folic Acid DMEMBJC Colorectal carcinoma Approved [30]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [31]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [32]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [33]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [34]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [35]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [36]
Oxaliplatin DMQNWRD Adenocarcinoma 2D40 Approved [37]
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Drug(s) Transported By P-glycoprotein 1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [23]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [38]
Methotrexate DM2TEOL Anterior urethra cancer Approved [39]
Folic Acid DMEMBJC Colorectal carcinoma Approved [40]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [39]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [39]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [41]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [39]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [42]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [43]
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Drug(s) Transported By Breast cancer resistance protein (ABCG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [44]
Methotrexate DM2TEOL Anterior urethra cancer Approved [45]
Folic Acid DMEMBJC Colorectal carcinoma Approved [46]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [47]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [48]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [49]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [50]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [49]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [51]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [52]
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Drug(s) Transported By Multidrug resistance protein 3 (ABCB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [4]
Digoxin DMQCTIH Arrhythmia BC9Z Approved [4]
SILODOSIN DMJSBT6 Benign prostatic hyperplasia GA90 Approved [53]
Paclitaxel DMLB81S Breast carcinoma Approved [4]
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [54]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [55]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [56]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [57]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [58]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [59]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [60]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [61]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [55]
Verapamil DMA7PEW Angina pectoris BA40 Approved [62]
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Drug(s) Metabolized By Cytochrome P450 2D6 (CYP2D6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [10]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [63]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [64]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [58]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [62]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [65]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [66]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [67]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [68]
Propranolol DM79NTF Angina pectoris BA40 Approved [69]
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Drug(s) Metabolized By Cytochrome P450 3A5 (CYP3A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [11]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [70]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [71]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [73]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [74]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [75]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [76]
Verapamil DMA7PEW Angina pectoris BA40 Approved [77]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [72]
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Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [86]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [87]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [88]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [89]
Cepharanthine DM9Y5JB N. A. N. A. Approved [90]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [91]
Clozapine DMFC71L Schizophrenia 6A20 Approved [92]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [93]
Trifluoperazine DMKBYWI Anxiety Approved [94]
Olanzapine DMPFN6Y Bipolar depression Approved [92]
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Drug(s) Affected By ATP-binding cassette sub-family C member 2 (ABCC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lopinavir DMITQS0 Human immunodeficiency virus infection 1C62 Approved [95]
Sulfinpyrazone DMEV954 Gout FA25 Approved [96]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [14]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [97]
Methotrexate DM2TEOL Anterior urethra cancer Approved [79]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [98]
Cholic Acid DM7OKQV Cholelithiasis DC11 Approved [99]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [83]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [100]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
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Drug(s) Affected By Bile salt export pump (ABCB11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [102]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [103]
Glipizide DMZA5PQ Diabetic complication 5A2Y Approved [103]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [104]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [102]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [103]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [105]
Gefitinib DM15F0X Colon adenocarcinoma Approved [102]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [106]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [102]
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Drug(s) Affected By Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [107]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [108]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [109]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [111]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ibrutinib DMHZCPO Mantle cell lymphoma 2A85.5 Approved [114]
Sulfasalazine DMICA9H Irritable bowel syndrome DD91.0 Approved [115]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [116]
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Drug(s) Affected By Nuclear receptor subfamily 1 group I member 2 (NR1I2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [117]
Vidarabine DM0N85H Hepatosplenic T-cell lymphoma Approved [117]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [118]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [119]
Secobarbital DM14RF5 Epilepsy 8A60-8A68 Approved [120]
Etidronic acid DM1XHYJ Bone Paget disease Approved [117]
Tiaprofenic acid DM23D7J Osteoarthritis FA00-FA05 Approved [117]
Bromperidol DM24XYQ Schizophrenia 6A20 Approved [117]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [121]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [122]
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Drug(s) Affected By Superoxide dismutase , mitochondrial (SOD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Selenium DM25CGV N. A. N. A. Approved [124]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [126]
Epinephrine DM3KJBC Acute asthma CA23 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [128]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [129]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [130]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
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Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [125]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [133]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [135]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [136]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [139]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [125]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [141]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [141]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [142]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [143]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [144]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [145]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [146]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [147]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [148]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [149]
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Drug(s) Affected By Transcription factor Jun (JUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [150]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [151]
Fructose DM43AN2 Vomiting MD90 Approved [142]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [152]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [153]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [154]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [157]
Methotrexate DM2TEOL Anterior urethra cancer Approved [158]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-8 (CXCL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [159]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [160]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [161]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [135]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [153]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [164]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [162]
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Drug(s) Affected By Integrin alpha-L (ITGAL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [167]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [169]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Paclitaxel DMLB81S Breast carcinoma Approved [170]
Bortezomib DMNO38U Leukemia Approved [171]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
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Drug(s) Affected By NF-kappa-B inhibitor alpha (NFKBIA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [142]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [173]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [107]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [175]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [176]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [177]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 8 (MAPK8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [179]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [152]
Gefitinib DM15F0X Colon adenocarcinoma Approved [180]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [123]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [157]
Quercetin DM3NC4M Obesity 5B81 Approved [181]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [182]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [183]
Ethacrynic acid DM60QMR Edema MG29 Approved [184]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [185]
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Drug(s) Affected By Mitogen-activated protein kinase 9 (MAPK9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [152]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [157]
Methotrexate DM2TEOL Anterior urethra cancer Approved [186]
Quercetin DM3NC4M Obesity 5B81 Approved [187]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [188]
Sorbitol DMAN0DE Constipation DD91.1 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
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Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Gefitinib DM15F0X Colon adenocarcinoma Approved [193]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [194]
Epinephrine DM3KJBC Acute asthma CA23 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [196]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [197]
Fructose DM43AN2 Vomiting MD90 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [199]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [200]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [201]
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Drug(s) Affected By Protein kinase C delta type (PRKCD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [202]
Butorphanol DM5KYPJ Pain MG30-MG3Z Approved [203]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [204]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [205]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [208]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
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Drug(s) Affected By Nuclear factor of activated T-cells, cytoplasmic 4 (NFATC4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [210]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ethanol DMDRQZU Chronic pain MG30 Approved [212]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [213]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
Phenylephrine DMZHUO5 Allergic rhinitis CA08.0 Approved [215]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [211]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [216]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [217]
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Drug(s) Affected By Transcriptional regulator QRICH1 (QRICH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Paclitaxel DMLB81S Breast carcinoma Approved [218]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [219]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [221]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Sorting nexin-10 (SNX10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [224]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [225]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.2 (H1-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [230]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-1 beta (IL1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [174]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Gefitinib DM15F0X Colon adenocarcinoma Approved [233]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [162]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [139]
Selenium DM25CGV N. A. N. A. Approved [124]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [234]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [235]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Friend leukemia integration 1 transcription factor (FLI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [237]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [238]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [192]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfotransferase 1A1 (SULT1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [241]
Minoxidil DMA2Z4F Alopecia ED70 Approved [242]
Benzyl alcohol DMBVYDI Head and body lice 1G00.0 Approved [243]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [242]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [244]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Methotrexate DM2TEOL Anterior urethra cancer Approved [246]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H3-like centromeric protein A (CENPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [249]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA polymerase zeta catalytic subunit (REV3L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [253]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [255]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [256]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [256]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rab11 family-interacting protein 1 (RAB11FIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Panobinostat DM58WKG Chronic graft versus host disease Approved [259]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxysterol-binding protein-related protein 10 (OSBPL10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [255]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [262]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein inhibitor ID-2 (ID2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Selenium DM25CGV N. A. N. A. Approved [264]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [265]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [266]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [267]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [202]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [268]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [265]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [269]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [270]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [219]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tripartite motif-containing protein 2 (TRIM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [272]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lamin-B1 (LMNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [274]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [276]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [277]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [278]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Borealin (CDCA8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [279]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [282]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [284]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Selenium DM25CGV N. A. N. A. Approved [285]
Etretinate DM2CZFA Keratosis ED56 Approved [286]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [287]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [288]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [272]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin complex subunit 3 (NCAPG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By m7GpppX diphosphatase (DCPS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Bortezomib DMNO38U Leukemia Approved [171]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By KN motif and ankyrin repeat domain-containing protein 1 (KANK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [291]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aldehyde oxidase (AOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [129]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [125]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [293]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [294]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By U11/U12 small nuclear ribonucleoprotein 25 kDa protein (SNRNP25)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [296]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pyruvate dehydrogenase E1 component subunit beta, mitochondrial (PDHB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [298]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [299]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [300]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [301]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-acetylglucosamine-1-phosphotransferase subunits alpha/beta (GNPTAB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ethanol DMDRQZU Chronic pain MG30 Approved [302]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Superoxide dismutase (SOD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [304]
Haloperidol DM96SE0 Delirium Approved [142]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [305]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [306]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [307]
Methotrexate DM2TEOL Anterior urethra cancer Approved [308]
Epinephrine DM3KJBC Acute asthma CA23 Approved [127]
Quercetin DM3NC4M Obesity 5B81 Approved [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 3 (BIRC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [310]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [173]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [311]
Methotrexate DM2TEOL Anterior urethra cancer Approved [312]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [267]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [313]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [314]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chromosome-associated kinesin KIF4A (KIF4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 beta subcomplex subunit 2, mitochondrial (NDUFB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Selenium DM25CGV N. A. N. A. Approved [264]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [298]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [316]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High mobility group protein B1 (HMGB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Gefitinib DM15F0X Colon adenocarcinoma Approved [233]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [318]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [319]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [320]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By c-Myc-binding protein (MYCBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hyaluronan mediated motility receptor (HMMR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [272]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [272]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription termination factor 2 (TTF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [291]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [325]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neprilysin (MME)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [326]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Folic Acid DMEMBJC Colorectal carcinoma Approved [327]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [328]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Arsenic DMTL2Y1 N. A. N. A. Approved [329]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Selenium DM25CGV N. A. N. A. Approved [264]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [330]
Bortezomib DMNO38U Leukemia Approved [171]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA topoisomerase 2-alpha (TOP2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [331]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [332]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [155]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [333]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [334]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [335]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Electron transfer flavoprotein subunit beta (ETFB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Flap endonuclease 1 (FEN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [337]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G-protein-signaling modulator 2 (GPSM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Testosterone enanthate DMB6871 N. A. N. A. Approved [338]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Promegestone DMK4S8I Gynecological disease GA6Z Approved [339]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen activator inhibitor 2 (SERPINB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [137]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [278]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [278]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [340]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [341]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CD40 ligand (CD40LG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [343]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [344]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [345]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [346]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [347]
Menthol DMG2KW7 Back pain ME84.Z Approved [348]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [349]
Eptifibatide DMQXTJS Acute cardiac ischemic events BA40.Z Approved [350]
Candesartan DMRK8OT Chronic heart failure BD1Z Approved [347]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [352]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleolar and spindle-associated protein 1 (NUSAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stanniocalcin-2 (STC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [354]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [272]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [249]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [356]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [357]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pirin (PIR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [278]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [268]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [230]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [358]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 alpha subcomplex subunit 7 (NDUFA7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [359]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [224]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [264]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [360]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [271]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [361]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [254]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By G0/G1 switch protein 2 (G0S2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Selenium DM25CGV N. A. N. A. Approved [124]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [362]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [363]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [364]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Replication protein A 14 kDa subunit (RPA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [366]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [367]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Folic Acid DMEMBJC Colorectal carcinoma Approved [368]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [369]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Deoxyribose-phosphate aldolase (DERA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase iron-sulfur protein 6, mitochondrial (NDUFS6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [370]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [361]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [371]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 subunit C2 (NDUFC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [372]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [373]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [296]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-glucuronidase (GUSB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [374]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [375]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [207]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fos-related antigen 1 (FOSL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [354]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [293]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [376]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [364]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [377]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High mobility group nucleosome-binding domain-containing protein 3 (HMGN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (NUDT4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [379]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine-rich PDZ-binding protein (CRIPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [258]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Replication factor C subunit 5 (RFC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [380]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Clozapine DMFC71L Schizophrenia 6A20 Approved [381]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [294]
Paclitaxel DMLB81S Breast carcinoma Approved [382]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit e, mitochondrial (ATP5ME)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Selenium DM25CGV N. A. N. A. Approved [264]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [370]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [383]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Indomethacin DMSC4A7 Bursitis Approved [384]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 14A (TMEM14A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [375]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By MAP kinase-activated protein kinase 5 (MAPKAPK5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [385]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [386]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
PMID26560530-Compound-35 DMO36RL N. A. N. A. Patented [388]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [371]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Shootin-1 (SHTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [389]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [389]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [214]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [390]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 2 (CDK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [284]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [391]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [392]
Selenium DM25CGV N. A. N. A. Approved [285]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [287]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [393]
Methotrexate DM2TEOL Anterior urethra cancer Approved [394]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [395]
Quercetin DM3NC4M Obesity 5B81 Approved [396]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibronectin (FN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [397]
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
Quercetin DM3NC4M Obesity 5B81 Approved [398]
Aripiprazole DM3NUMH Bipolar I disorder Approved [399]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [400]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [401]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ethacrynic acid DM60QMR Edema MG29 Approved [402]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [403]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [404]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-like growth factor 2 mRNA-binding protein 3 (IGF2BP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Arsenic DMTL2Y1 N. A. N. A. Approved [405]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [207]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Membrane-associated progesterone receptor component 1 (PGRMC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Gefitinib DM15F0X Colon adenocarcinoma Approved [406]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable ATP-dependent RNA helicase DDX23 (DDX23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [407]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [262]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [262]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [219]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM3C (FAM3C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [278]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [278]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [82]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 134 (TMEM134)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein kinase TTK (TTK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCN family member 2 (CCN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [408]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [354]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [362]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [409]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [125]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [410]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [356]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 4 inhibitor C (CDKN2C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [411]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [376]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytoskeleton-associated protein 2 (CKAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Testosterone enanthate DMB6871 N. A. N. A. Approved [338]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c oxidase copper chaperone (COX17)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [171]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [412]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [12]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Topotecan DMP6G8T Central nervous system neoplasm Approved [12]
Coprexa DMA0WEK Neurological disorder 6B60 Phase 3 [413]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tetraspanin-13 (TSPAN13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [207]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By S-phase kinase-associated protein 2 (SKP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [414]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [415]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Succinate--CoA ligase subunit alpha, mitochondrial (SUCLG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Benzatropine DMF7EXL Parkinsonian disorder Approved [381]
Clozapine DMFC71L Schizophrenia 6A20 Approved [381]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [416]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome activator complex subunit 4 (PSME4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Testosterone enanthate DMB6871 N. A. N. A. Approved [338]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-adducin (ADD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Selenium DM25CGV N. A. N. A. Approved [264]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [337]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [418]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Superkiller complex protein 8 (SKIC8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dickkopf-related protein 3 (DKK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [192]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Folic Acid DMEMBJC Colorectal carcinoma Approved [419]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [420]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Geminin (GMNN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By EF-hand calcium-binding domain-containing protein 7 (EFCAB7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [232]
OXYQUINOLINE DMZVS9Y Discovery agent N.A. Investigative [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Vitamin K-dependent gamma-carboxylase (GGCX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [207]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [421]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [219]
Nickel chloride DMI12Y8 Discovery agent N.A. Investigative [422]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit f, mitochondrial (ATP5MF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [359]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [423]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Maternal embryonic leucine zipper kinase (MELK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein pelota homolog (PELO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [424]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [425]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [426]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [424]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [424]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [424]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serglycin (SRGN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [298]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [427]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sortilin (SORT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [381]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Testosterone DM7HUNW Hot flushes GA30 Approved [428]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exosome complex component RRP45 (EXOSC9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [207]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 2 (BIRC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paclitaxel DMLB81S Breast carcinoma Approved [310]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [173]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [429]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [411]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [430]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [410]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [431]
Trovafloxacin DM6AN32 Acute gonococcal cervicitis Approved [314]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [432]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [433]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High mobility group protein B2 (HMGB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [434]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [435]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [249]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipid-transporting ATPase ABCA3 (ABCA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [436]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [437]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [407]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Indomethacin DMSC4A7 Bursitis Approved [438]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sigma intracellular receptor 2 (TMEM97)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane protein 156 (TMEM156)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [439]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Epithelial cell adhesion molecule (EPCAM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [440]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Paclitaxel DMLB81S Breast carcinoma Approved [441]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [442]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein regulator of cytokinesis 1 (PRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [408]
Methotrexate DM2TEOL Anterior urethra cancer Approved [443]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [230]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catalase (CAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [163]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [444]
Haloperidol DM96SE0 Delirium Approved [142]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [445]
Selenium DM25CGV N. A. N. A. Approved [446]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [447]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [448]
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [449]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF11 (KIF11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [450]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Actin-binding LIM protein 1 (ABLIM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [451]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [452]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By U6 snRNA-associated Sm-like protein LSm7 (LSM7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [453]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [454]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [264]
PP-242 DM2348V Discovery agent N.A. Investigative [455]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [456]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [297]
Milchsaure DM462BT Pruritus EC90 Investigative [457]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF1B (KIF1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [458]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [264]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [459]
Etretinate DM2CZFA Keratosis ED56 Approved [460]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [461]
Methotrexate DM2TEOL Anterior urethra cancer Approved [312]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [462]
Quercetin DM3NC4M Obesity 5B81 Approved [463]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [464]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [465]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [268]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein Mis18-beta (OIP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [214]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B2 (CCNB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [466]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [376]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [422]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Securin (PTTG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [467]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [422]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [468]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 7 (BIRC7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [343]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Bortezomib DMNO38U Leukemia Approved [469]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [269]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [470]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [471]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [471]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [472]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aurora kinase B (AURKB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [434]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [288]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [230]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 subunit C1, mitochondrial (NDUFC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [370]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [473]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [359]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [316]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Low molecular weight phosphotyrosine protein phosphatase (ACP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [474]
Aminoglutethimide DMWFHMZ Cushing disease 5A70 Approved [475]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [476]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [264]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [301]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G/T mismatch-specific thymine DNA glycosylase (TDG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Indomethacin DMSC4A7 Bursitis Approved [384]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase FANCL (FANCL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [477]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [256]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial (HADH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [416]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [359]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysophosphatidic acid receptor 1 (LPAR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [437]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [478]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [452]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [227]
Methotrexate DM2TEOL Anterior urethra cancer Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [479]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF15 (KIF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [352]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By TBC1 domain family member 4 (TBC1D4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Azacitidine DMTA5OE Acute myelogenous leukaemia 2A41 Approved [224]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [480]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase receptor UFO (AXL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [481]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [380]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [481]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [482]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [230]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [230]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-glutamylcyclotransferase (GGCT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [426]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [379]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [483]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 alpha subcomplex subunit 1 (NDUFA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Fenretinide DMRD5SP Macular degeneration 9B78.3 Phase 3 [484]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Origin recognition complex subunit 6 (ORC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [294]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sideroflexin-1 (SFXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [485]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [486]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lamina-associated polypeptide 2, isoform alpha (TMPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Quercetin DM3NC4M Obesity 5B81 Approved [258]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor E2F1 (E2F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [487]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [391]
Gefitinib DM15F0X Colon adenocarcinoma Approved [488]
Selenium DM25CGV N. A. N. A. Approved [264]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [424]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [489]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [380]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Striatin (STRN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [324]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [211]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [264]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Succinate--CoA ligase subunit beta, mitochondrial (SUCLA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [473]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [490]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [491]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein downstream neighbor of Son (DONSON)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [172]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [321]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [297]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c oxidase subunit 6B1 (COX6B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [492]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [271]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [493]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratinocyte-associated transmembrane protein 2 (C5ORF15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
Drug(s) Affected By Receptor tyrosine-protein kinase erbB-2 (ERBB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Trastuzumab DMZQOUX Breast cancer 2C60-2C65 Approved [142]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [494]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [495]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [496]
Gefitinib DM15F0X Colon adenocarcinoma Approved [497]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [165]
Selenium DM25CGV N. A. N. A. Approved [264]
Methotrexate DM2TEOL Anterior urethra cancer Approved [312]
Quercetin DM3NC4M Obesity 5B81 Approved [396]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By tRNA (TRMT5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [262]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [262]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [498]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [297]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Ribonucleoside-diphosphate reductase subunit M2 (RRM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [499]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c oxidase subunit 5A, mitochondrial (COX5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [500]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Capsaicin DMGMF6V Back pain ME84.Z Approved [501]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [315]
Arsenic DMTL2Y1 N. A. N. A. Approved [502]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [493]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA fragmentation factor subunit beta (DFFB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [503]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [202]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [366]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-13 receptor subunit alpha-2 (IL13RA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [504]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [451]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [477]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [505]
Arsenic DMTL2Y1 N. A. N. A. Approved [506]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [507]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Testosterone enanthate DMB6871 N. A. N. A. Approved [338]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Artesunate DMR27C8 Infection of P. falciparum 1F40 Approved [508]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kazrin (KAZN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [505]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [389]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [12]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2 and S phase-expressed protein 1 (GTSE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [132]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [279]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [450]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [282]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostaglandin E synthase 3 (PTGES3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [509]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [142]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Epithelial membrane protein 2 (EMP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [510]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [511]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [512]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [513]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ornithine decarboxylase antizyme 1 (OAZ1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Folic Acid DMEMBJC Colorectal carcinoma Approved [514]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [456]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sister chromatid cohesion protein DCC1 (DSCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [134]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [378]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [515]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [154]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [496]
Gefitinib DM15F0X Colon adenocarcinoma Approved [516]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [268]
Selenium DM25CGV N. A. N. A. Approved [285]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [517]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [518]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [519]
Methotrexate DM2TEOL Anterior urethra cancer Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pentraxin-related protein PTX3 (PTX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [124]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [520]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [294]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [477]
Bortezomib DMNO38U Leukemia Approved [521]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ran-specific GTPase-activating protein (RANBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [342]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [468]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [468]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rac GTPase-activating protein 1 (RACGAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [380]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [422]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By MAPK/MAK/MRK overlapping kinase (MOK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [411]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [522]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [523]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [12]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Topotecan DMP6G8T Central nervous system neoplasm Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [524]
Testosterone DM7HUNW Hot flushes GA30 Approved [525]
Dydrogesterone DMAKIDV Menstrual disorder GA20.3 Approved [526]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [527]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Dutasteride DMQ4TJK Benign prostatic hyperplasia GA90 Approved [528]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [526]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Solute carrier family 22 member 3 (SLC22A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Epinephrine DM3KJBC Acute asthma CA23 Approved [529]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [529]
Norepinephrine DMOUC09 Alopecia ED70 Approved [529]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [352]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [530]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [531]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [451]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Large ribosomal subunit protein mL63 (MRPL57)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Topotecan DMP6G8T Central nervous system neoplasm Approved [12]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [532]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [297]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Dickkopf-related protein 1 (DKK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Quercetin DM3NC4M Obesity 5B81 Approved [533]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [422]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [534]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Olfactory receptor 1I1 (OR1I1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
Drug(s) Affected By Protein CREG1 (CREG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [252]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Arsenic DMTL2Y1 N. A. N. A. Approved [535]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [252]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [214]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proepiregulin (EREG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [162]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [162]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [312]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [536]
Penbutolol DM4ES8F Hypertension BA00-BA04 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinetochore protein NDC80 homolog (NDC80)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [352]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [537]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Latent-transforming growth factor beta-binding protein 2 (LTBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Folic Acid DMEMBJC Colorectal carcinoma Approved [514]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [207]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [12]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein D53 (TPD52L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [230]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [230]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [230]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [230]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Inhibin beta A chain (INHBA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [353]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [407]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [451]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [254]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [505]
Arsenic DMTL2Y1 N. A. N. A. Approved [538]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Leucine-rich repeat-containing protein 1 (LRRC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [225]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [389]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [217]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase flavoprotein 2, mitochondrial (NDUFV2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [298]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [539]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [540]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasminogen activator inhibitor 1 (SERPINE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [541]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [354]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [542]
Methotrexate DM2TEOL Anterior urethra cancer Approved [543]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [544]
Quercetin DM3NC4M Obesity 5B81 Approved [545]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [130]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [546]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [293]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [366]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho GTPase-activating protein SYDE1 (SYDE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [273]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Urethane DM7NSI0 N. A. N. A. Phase 4 [295]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [264]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Isocitrate dehydrogenase , mitochondrial (IDH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [547]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [383]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Folic Acid DMEMBJC Colorectal carcinoma Approved [548]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Paclitaxel DMLB81S Breast carcinoma Approved [549]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Importin subunit alpha-1 (KPNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [550]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [551]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [552]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [280]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By General transcription factor II-I (GTF2I)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [272]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [171]
Paclitaxel DMLB81S Breast carcinoma Approved [549]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [553]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin beta-1-binding protein 1 (ITGB1BP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [450]
Heroin diacetylmorphine DMDBWHY Neurological disorder 6B60 Approved [554]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [555]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [478]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [556]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [323]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [557]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor IIIA (GTF3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [363]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [558]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [371]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-binding cassette sub-family A member 2 (ABCA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [559]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [560]
Bortezomib DMNO38U Leukemia Approved [171]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [227]
Methotrexate DM2TEOL Anterior urethra cancer Approved [13]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [284]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Selenium DM25CGV N. A. N. A. Approved [285]
Etretinate DM2CZFA Keratosis ED56 Approved [286]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [561]
Methotrexate DM2TEOL Anterior urethra cancer Approved [312]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [380]
Quercetin DM3NC4M Obesity 5B81 Approved [396]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase 26 (STK26)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [437]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [101]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [247]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homer protein homolog 1 (HOMER1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Selenium DM25CGV N. A. N. A. Approved [264]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [562]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [290]
Arsenic DMTL2Y1 N. A. N. A. Approved [289]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acyl-coenzyme A thioesterase 13 (ACOT13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [245]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [222]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [262]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [262]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [257]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Divergent protein kinase domain 1A (DIPK1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [563]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [564]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [214]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [232]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [211]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Urokinase-type plasminogen activator (PLAU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [481]
Methotrexate DM2TEOL Anterior urethra cancer Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [565]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [481]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [566]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [567]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hematopoietic lineage cell-specific protein (HCLS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [355]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [568]
Testosterone enanthate DMB6871 N. A. N. A. Approved [338]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [477]
Arsenic DMTL2Y1 N. A. N. A. Approved [538]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [379]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleotide triphosphate diphosphatase NUDT15 (NUDT15)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [207]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [261]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
Mercaptopurine DMTM2IK Acute lymphoblastic leukaemia 2A85 Approved [569]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [221]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [113]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [412]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [317]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [380]
Quercetin DM3NC4M Obesity 5B81 Approved [398]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [570]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF20A (KIF20A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [257]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [424]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Condensin complex subunit 2 (NCAPH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [247]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [571]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Haloperidol DM96SE0 Delirium Approved [381]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [279]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [232]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin-like protein KIF23 (KIF23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [352]
Methotrexate DM2TEOL Anterior urethra cancer Approved [275]
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [228]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [168]
Testosterone DM7HUNW Hot flushes GA30 Approved [250]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [572]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [250]
Leflunomide DMR8ONJ Arthritis FA20 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAN (NSMAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [264]
Panobinostat DM58WKG Chronic graft versus host disease Approved [573]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Menthol DMG2KW7 Back pain ME84.Z Approved [348]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [574]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
Topotecan DMP6G8T Central nervous system neoplasm Approved [12]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proteasome subunit beta type-1 (PSMB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [575]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [364]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [231]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [226]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [476]
Paclitaxel DMLB81S Breast carcinoma Approved [12]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [387]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acetyl-CoA acetyltransferase, cytosolic (ACAT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [229]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [571]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [260]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Clozapine DMFC71L Schizophrenia 6A20 Approved [576]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [577]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G-protein coupled receptor 176 (GPR176)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [452]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [214]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [227]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [12]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [214]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [220]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [192]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Tissue factor pathway inhibitor 2 (TFPI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [178]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [110]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [206]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [190]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [209]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-X-C motif chemokine 5 (CXCL5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [283]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [354]
Panobinostat DM58WKG Chronic graft versus host disease Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [417]
Testosterone DM7HUNW Hot flushes GA30 Approved [112]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [191]
Clozapine DMFC71L Schizophrenia 6A20 Approved [578]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [451]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [281]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [579]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Tubulin beta-2 chain (TUBB2) TTJ2PTI TBB2A_HUMAN Inhibitor [3]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Multidrug resistance protein 3 (ABCB4) DTZRMK5 MDR3_HUMAN Substrate [4]
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [5]
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [6]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [7]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [8]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) Main DME DE4LYSA CP3A4_HUMAN Substrate [9]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Substrate [10]
Cytochrome P450 3A5 (CYP3A5) DEIBDNY CP3A5_HUMAN Substrate [11]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
14-3-3 protein theta OTWG7F3H 1433T_HUMAN Drug Response [12]
3-oxo-5-alpha-steroid 4-dehydrogenase 1 (SRD5A1) OTQRET2B S5A1_HUMAN Drug Response [12]
Acetyl-CoA acetyltransferase, cytosolic (ACAT2) OTZ092ZJ THIC_HUMAN Drug Response [12]
Actin-binding LIM protein 1 (ABLIM1) OTHXEK3E ABLM1_HUMAN Drug Response [12]
Acyl-coenzyme A thioesterase 13 (ACOT13) OTWRUST1 ACO13_HUMAN Drug Response [12]
Aldehyde oxidase (AOX1) OT2FZP6H AOXA_HUMAN Drug Response [12]
ATP synthase subunit e, mitochondrial (ATP5ME) OTADVEE2 ATP5I_HUMAN Drug Response [12]
ATP synthase subunit f, mitochondrial (ATP5MF) OTE4TBG9 ATPK_HUMAN Drug Response [12]
ATP-binding cassette sub-family A member 2 (ABCA2) OTVSYK0X ABCA2_HUMAN Drug Response [13]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Regulation of Drug Effects [14]

References

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8 Xenopus laevis oocytes expressing human P-glycoprotein: probing trans- and cis-inhibitory effects on [3H]vinblastine and [3H]digoxin efflux. Pharmacol Res. 2010 Jan;61(1):76-84.
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31 Enhancing chemosensitivity in oral squamous cell carcinoma by lentivirus vector-mediated RNA interference targeting EGFR and MRP2. Oncol Lett. 2016 Sep;12(3):2107-2114.
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33 Lentivirus-mediated RNAi silencing targeting ABCC2 increasing the sensitivity of a human nasopharyngeal carcinoma cell line against cisplatin. J Transl Med. 2008 Oct 4;6:55.
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37 Multidrug Resistance-Associated Protein 2 (MRP2) Mediated Transport of Oxaliplatin-Derived Platinum in Membrane Vesicles. PLoS One. 2015 Jul 1;10(7):e0130727.
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43 Association of genetic polymorphisms in the influx transporter SLCO1B3 and the efflux transporter ABCB1 with imatinib pharmacokinetics in patients with chronic myeloid leukemia. Ther Drug Monit. 2011 Apr;33(2):244-50.
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45 Wild-type breast cancer resistance protein (BCRP/ABCG2) is a methotrexate polyglutamate transporter. Cancer Res. 2003 Sep 1;63(17):5538-43.
46 The effect of low pH on breast cancer resistance protein (ABCG2)-mediated transport of methotrexate, 7-hydroxymethotrexate, methotrexate diglutamate, folic acid, mitoxantrone, topotecan, and resveratrol in in vitro drug transport models. Mol Pharmacol. 2007 Jan;71(1):240-9.
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49 Sterol transport by the human breast cancer resistance protein (ABCG2) expressed in Lactococcus lactis. J Biol Chem. 2003 Jun 6;278(23):20645-51.
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59 Potent mechanism-based inhibition of CYP3A4 by imatinib explains its liability to interact with CYP3A4 substrates. Br J Pharmacol. 2012 Apr;165(8):2787-98.
60 Effects of morin on the pharmacokinetics of etoposide in rats. Biopharm Drug Dispos. 2007 Apr;28(3):151-6.
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72 Drug Interactions Flockhart Table
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74 Urinary 6 beta-hydroxycortisol excretion in rheumatoid arthritis. Br J Rheumatol. 1997 Jan;36(1):54-8.
75 Clinical pharmacokinetics of imatinib. Clin Pharmacokinet. 2005;44(9):879-94.
76 Kinetics and regulation of cytochrome P450-mediated etoposide metabolism. Drug Metab Dispos. 2004 Sep;32(9):993-1000.
77 Differential mechanism-based inhibition of CYP3A4 and CYP3A5 by verapamil. Drug Metab Dispos. 2005 May;33(5):664-71.
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