Details of the Drug Combination

General Information of Drug Combination (ID: DCGF04P)

Drug Combination Name
Paclitaxel Bortezomib
Indication
Disease Entry Status REF
Unspecified Adult Solid Tumor, Protocol Specific Phase 1 [1]
Component Drugs Paclitaxel   DMLB81S Bortezomib   DMNO38U
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Paclitaxel
Disease Entry ICD 11 Status REF
Breast carcinoma N.A. Approved [2]
Cutaneous melanoma 2C30 Approved [2]
Cutaneous squamous cell carcinoma 2C30 Approved [2]
Epithelial ovarian cancer 2B5D Approved [2]
Extragonadal germ cell tumor N.A. Approved [2]
Fallopian tube neoplasm N.A. Approved [2]
Gastroesophageal junction adenocarcinoma 2B71 Approved [2]
Inflammatory breast cancer 2C62 Approved [2]
Kaposi sarcoma 2B57 Approved [2]
Lung adenocarcinoma N.A. Approved [2]
Lung cancer 2C25.0 Approved [2]
Non-small-cell lung cancer 2C25.Y Approved [2]
Ocular hypertension 9C61.01 Approved [2]
Ovarian neoplasm N.A. Approved [2]
Ovarian serous cystadenocarcinoma N.A. Approved [2]
Pain MG30-MG3Z Approved [2]
Pancreatic ductal carcinoma 2C10.0 Approved [2]
Primary peritoneal carcinoma N.A. Approved [2]
Testicular germ cell tumor N.A. Approved [2]
Urethral cancer 2C93 Approved [2]
Lung large cell carcinoma N.A. Investigative [2]
Paclitaxel Interacts with 11 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
Multidrug resistance-associated protein 1 (ABCC1) DTSYQGK MRP1_HUMAN Substrate [19]
Multidrug resistance-associated protein 2 (ABCC2) DTFI42L MRP2_HUMAN Substrate [20]
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [21]
Breast cancer resistance protein (ABCG2) DTI7UX6 ABCG2_HUMAN Substrate [22]
Organic anion transporter 2 (SLC22A7) DT0OC1Q S22A7_HUMAN Substrate [23]
Organic anion transporting polypeptide 1B1 (SLCO1B1) DT3D8F0 SO1B1_HUMAN Substrate [24]
Multidrug resistance-associated protein 3 (ABCC3) DTQ3ZHF MRP3_HUMAN Substrate [25]
Multidrug resistance protein 3 (ABCB4) DTZRMK5 MDR3_HUMAN Substrate [26]
Organic anion transporting polypeptide 1B3 (SLCO1B3) DT9C1TS SO1B3_HUMAN Substrate [27]
TAP-like protein (ABCB9) DT68UV2 ABCB9_HUMAN Substrate [28]
Multidrug resistance-associated protein 7 (ABCC10) DTPS120 MRP7_HUMAN Substrate [29]
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⏷ Show the Full List of 11 DTP(s)
Paclitaxel Interacts with 478 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Decreases Expression [30]
ATP-binding cassette sub-family C member 10 (ABCC10) OT2JRWWJ MRP7_HUMAN Increases Expression [31]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Expression [31]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Decreases Response To Substance [32]
Multidrug resistance-associated protein 1 (ABCC1) OTGUN89S MRP1_HUMAN Decreases Response To Substance [33]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Decreases Response To Substance [34]
Phosphatidylcholine translocator ABCB4 (ABCB4) OTE6PY83 MDR3_HUMAN Decreases Response To Substance [35]
Solute carrier family 22 member 7 (SLC22A7) OTKTNH1W S22A7_HUMAN Increases Transport [23]
Cyclin-dependent kinase 20 (CDK20) OTOLNN68 CDK20_HUMAN Decreases Expression [36]
Alkaline phosphatase, tissue-nonspecific isozyme (ALPL) OTG7J4BP PPBT_HUMAN Increases ADR [6]
Lipoprotein lipase (LPL) OTTW0267 LIPL_HUMAN Increases ADR [6]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Activity [37]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Increases Expression [38]
TNF receptor-associated factor 1 (TRAF1) OTTLM5RU TRAF1_HUMAN Decreases Expression [36]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Decreases Expression [39]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Decreases Expression [39]
Bcl2-associated agonist of cell death (BAD) OT63ERYM BAD_HUMAN Increases Expression [11]
Poly polymerase 1 (PARP1) OTIESHK4 PARP1_ARATH Increases ADR [6]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Activity [40]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Increases Activity [41]
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Increases Expression [42]
Dihydropyrimidine dehydrogenase (DPYD) OTWRF2NR DPYD_HUMAN Decreases Expression [7]
Arylamine N-acetyltransferase 1 (NAT1) OTCCNQ3H ARY1_HUMAN Decreases Activity [43]
NAD-dependent protein deacetylase sirtuin-1 (SIRT1) OTAYZMOY SIR1_HUMAN Decreases Expression [44]
Nitric oxide synthase 3 (NOS3) OTLDT7NR NOS3_HUMAN Decreases Expression [37]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Increases Expression [37]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Decreases Activity [45]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Decreases Activity [45]
Cytochrome P450 2C9 (CYP2C9) OTGLBN29 CP2C9_HUMAN Decreases Activity [45]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Decreases Activity [46]
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) OTBPCU2O TR10A_HUMAN Increases Expression [47]
DNA fragmentation factor subunit alpha (DFFA) OTFPFMT8 DFFA_HUMAN Decreases Expression [9]
Sulfhydryl oxidase 1 (QSOX1) OT4ZPK4P QSOX1_HUMAN Decreases Expression [8]
Serine/threonine-protein kinase PLK4 (PLK4) OTV8KZDZ PLK4_HUMAN Decreases Expression [8]
TNF receptor-associated factor 5 (TRAF5) OTSBTLO0 TRAF5_HUMAN Decreases Expression [8]
Myc box-dependent-interacting protein 1 (BIN1) OTK8O0X8 BIN1_HUMAN Increases Expression [48]
Nucleoside diphosphate kinase, mitochondrial (NME4) OT2JTT42 NDKM_HUMAN Decreases Expression [9]
Potassium channel subfamily K member 3 (KCNK3) OTWMAV6G KCNK3_HUMAN Increases Expression [9]
Apoptotic protease-activating factor 1 (APAF1) OTJWIVY0 APAF_HUMAN Increases Expression [39]
Acyl-coenzyme A thioesterase 8 (ACOT8) OTHY684G ACOT8_HUMAN Decreases Expression [49]
Telomerase reverse transcriptase (TERT) OT085VVA TERT_HUMAN Decreases Expression [50]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [47]
Neuropilin-1 (NRP1) OTCGULYV NRP1_HUMAN Increases Expression [48]
Aurora kinase A (AURKA) OTMX0HYT AURKA_HUMAN Increases Expression [51]
Mitogen-activated protein kinase 13 (MAPK13) OT0W9GE7 MK13_HUMAN Increases Expression [9]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [52]
High affinity copper uptake protein 1 (SLC31A1) OTXLRTUB COPT1_HUMAN Increases Expression [31]
ATP-binding cassette sub-family C member 5 (ABCC5) OT34G4US MRP5_HUMAN Increases Expression [31]
N-glycosylase/DNA lyase (OGG1) OTJ97TF3 OGG1_HUMAN Increases Expression [9]
Retinoschisin (RS1) OTEW1ZM5 XLRS1_HUMAN Decreases Secretion [53]
Kunitz-type protease inhibitor 2 (SPINT2) OTQV7BKQ SPIT2_HUMAN Decreases Expression [48]
Adenylate cyclase type 6 (ADCY6) OTFOY4WW ADCY6_HUMAN Decreases Expression [8]
Protein regulator of cytokinesis 1 (PRC1) OTHD0XS0 PRC1_HUMAN Increases Expression [51]
Mitotic checkpoint protein BUB3 (BUB3) OTU91HAU BUB3_HUMAN Increases Expression [9]
Phospholipid phosphatase 2 (PLPP2) OT0BQAXX PLPP2_HUMAN Decreases Expression [48]
Myelin protein zero-like protein 2 (MPZL2) OTKFNDUI MPZL2_HUMAN Decreases Expression [48]
Dual specificity protein phosphatase CDC14B (CDC14B) OTAESVOZ CC14B_HUMAN Decreases Expression [36]
Hyaluronan mediated motility receptor (HMMR) OT4M0JTZ HMMR_HUMAN Decreases Expression [9]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1) OTY9R6FZ ERN1_HUMAN Increases Expression [54]
Death effector domain-containing protein (DEDD) OTIL349E DEDD_HUMAN Decreases Expression [8]
Serine hydrolase RBBP9 (RBBP9) OT0Z04L6 RBBP9_HUMAN Decreases Expression [8]
Tumor necrosis factor ligand superfamily member 13 (TNFSF13) OT90OWIO TNF13_HUMAN Increases Expression [36]
ATP-dependent Clp protease ATP-binding subunit clpX-like, mitochondrial (CLPX) OTIT4JL0 CLPX_HUMAN Increases Expression [9]
Apoptosis-inducing factor 1, mitochondrial (AIFM1) OTKPWB7Q AIFM1_HUMAN Increases Expression [36]
Securin (PTTG1) OTIMYS4W PTTG1_HUMAN Affects Expression [55]
G1/S-specific cyclin-E2 (CCNE2) OTBBUKQQ CCNE2_HUMAN Decreases Expression [8]
Aldehyde dehydrogenase 1A1 (ALDH1A1) OTCUWZKB AL1A1_HUMAN Decreases Expression [56]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Decreases Expression [36]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [9]
Pro-epidermal growth factor (EGF) OTANRJ0L EGF_HUMAN Decreases Expression [36]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Increases Expression [57]
Collagen alpha-1(I) chain (COL1A1) OTI31178 CO1A1_HUMAN Increases Expression [48]
Collagen alpha-1(IV) chain (COL4A1) OTL6D1YE CO4A1_HUMAN Increases Expression [48]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Increases Expression [58]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Increases Phosphorylation [59]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Increases Expression [60]
Thy-1 membrane glycoprotein (THY1) OTVONVTB THY1_HUMAN Increases Expression [48]
Apolipoprotein D (APOD) OTT77XW8 APOD_HUMAN Increases Expression [48]
Propionyl-CoA carboxylase alpha chain, mitochondrial (PCCA) OTWJTCRK PCCA_HUMAN Decreases Expression [9]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Increases Phosphorylation [54]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Increases Expression [61]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Decreases Expression [62]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Increases Phosphorylation [63]
Transcription factor AP-2-alpha (TFAP2A) OTMYT3NK AP2A_HUMAN Increases Expression [64]
Keratin, type I cytoskeletal 18 (KRT18) OTVLQFIP K1C18_HUMAN Increases Expression [65]
Gelsolin (GSN) OT4KS2UU GELS_HUMAN Decreases Expression [8]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Increases Phosphorylation [66]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Decreases Expression [36]
Fatty acid-binding protein, liver (FABP1) OTR34ETM FABPL_HUMAN Decreases Expression [49]
Prosaposin (PSAP) OTUOEKY7 SAP_HUMAN Decreases Expression [8]
Collagen alpha-2(IV) chain (COL4A2) OTJK1LKN CO4A2_HUMAN Increases Expression [48]
SPARC (SPARC) OTPN90H0 SPRC_HUMAN Increases Expression [48]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [67]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [61]
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Decreases Localization [68]
Microtubule-associated protein tau (MAPT) OTMTP2Z7 TAU_HUMAN Decreases Expression [69]
Cyclin-dependent kinase 4 (CDK4) OT7EP05T CDK4_HUMAN Decreases Expression [70]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Decreases Expression [70]
Collagen alpha-1(VI) chain (COL6A1) OTYKSCOB CO6A1_HUMAN Increases Expression [48]
Collagen alpha-2(VI) chain (COL6A2) OTQC6PPO CO6A2_HUMAN Increases Expression [48]
ADP/ATP translocase 1 (SLC25A4) OTKYLK2J ADT1_HUMAN Decreases Expression [8]
Bone morphogenetic protein 4 (BMP4) OTPZMDFH BMP4_HUMAN Decreases Expression [12]
Elongation factor 2 (EEF2) OTZ7SZ39 EF2_HUMAN Decreases Expression [8]
Glial fibrillary acidic protein (GFAP) OTQ01ZAS GFAP_HUMAN Increases Expression [71]
Interleukin-1 receptor type 1 (IL1R1) OTTU8959 IL1R1_HUMAN Decreases Expression [9]
Amphiregulin (AREG) OTJFOR67 AREG_HUMAN Increases Expression [72]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Increases Expression [73]
Epithelial cell adhesion molecule (EPCAM) OTHBZK5X EPCAM_HUMAN Decreases Expression [48]
Integrin beta-6 (ITGB6) OTI3DJ7U ITB6_HUMAN Decreases Expression [48]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Increases Expression [54]
DNA ligase 1 (LIG1) OTEEQS43 DNLI1_HUMAN Decreases Expression [8]
Sodium/hydrogen exchanger 1 (SLC9A1) OT6HNHFV SL9A1_HUMAN Decreases Activity [74]
Integrin alpha-L (ITGAL) OTCUQAIS ITAL_HUMAN Decreases Expression [62]
Ephrin-A1 (EFNA1) OTU2NUA2 EFNA1_HUMAN Decreases Expression [48]
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) OTVLI4DD TNAP3_HUMAN Increases Expression [36]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Increases Expression [61]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) OTBZKX4P ROA2_HUMAN Decreases Expression [8]
Insulin-like growth factor-binding protein 4 (IGFBP4) OT2HZRBD IBP4_HUMAN Increases Expression [48]
Carnitine O-palmitoyltransferase 2, mitochondrial (CPT2) OTIN6G20 CPT2_HUMAN Decreases Expression [49]
Follicle-stimulating hormone receptor (FSHR) OT9MVMLI FSHR_HUMAN Decreases Expression [12]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [70]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Increases Activity [75]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Decreases Expression [48]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Decreases Expression [76]
Protein S100-P (S100P) OTJCXNJG S100P_HUMAN Decreases Expression [48]
Protein S100-A4 (S100A4) OTLRGFSQ S10A4_HUMAN Increases Expression [48]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Phosphorylation [12]
Long-chain specific acyl-CoA dehydrogenase, mitochondrial (ACADL) OTP7Y0UF ACADL_HUMAN Decreases Expression [9]
Caspase-1 (CASP1) OTZ3YQFU CASP1_HUMAN Increases Expression [57]
M-phase inducer phosphatase 3 (CDC25C) OTPQI71S MPIP3_HUMAN Decreases Expression [36]
Adenylosuccinate synthetase isozyme 2 (ADSS2) OTW26XXB PURA2_HUMAN Decreases Expression [9]
RAC-beta serine/threonine-protein kinase (AKT2) OTBB632K AKT2_HUMAN Increases Phosphorylation [77]
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) OTFRWOLM HNRH1_HUMAN Decreases Expression [8]
Stress-induced-phosphoprotein 1 (STIP1) OT7TXLOX STIP1_HUMAN Increases Expression [9]
Syndecan-2 (SDC2) OTEEHY1D SDC2_HUMAN Increases Expression [48]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Decreases Phosphorylation [12]
Tyrosine-protein phosphatase non-receptor type 7 (PTPN7) OTXYSIIV PTN7_HUMAN Increases Expression [9]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Decreases Expression [9]
Fibrillin-1 (FBN1) OTYCJT63 FBN1_HUMAN Increases Expression [48]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [54]
Pigment epithelium-derived factor (SERPINF1) OTWZH98J PEDF_HUMAN Increases Expression [48]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Decreases Expression [78]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Decreases Expression [79]
Collagen alpha-1(XVIII) chain (COL18A1) OTJFUH6O COIA1_HUMAN Increases Expression [48]
Signal transducer and activator of transcription 3 (STAT3) OTAAGKYZ STAT3_HUMAN Decreases Activity [80]
Replication factor C subunit 5 (RFC5) OTAD79RT RFC5_HUMAN Decreases Expression [9]
Serine/threonine-protein kinase mTOR (MTOR) OTHH8KU7 MTOR_HUMAN Decreases Phosphorylation [70]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Expression [81]
Mitogen-activated protein kinase 8 (MAPK8) OTEREYS5 MK08_HUMAN Increases Activity [82]
Mitogen-activated protein kinase 9 (MAPK9) OTCEVJ9E MK09_HUMAN Increases Expression [83]
Tumor necrosis factor ligand superfamily member 6 (FASLG) OTZARCHH TNFL6_HUMAN Increases Expression [84]
Isocitrate dehydrogenase , mitochondrial (IDH2) OTTQA4PB IDHP_HUMAN Decreases Expression [8]
4-trimethylaminobutyraldehyde dehydrogenase (ALDH9A1) OTNWHUJ1 AL9A1_HUMAN Increases Expression [9]
Fatty acid synthase (FASN) OTFII9KG FAS_HUMAN Decreases Expression [49]
Centromere protein F (CENPF) OT7AG0SW CENPF_HUMAN Increases Expression [85]
Caspase-4 (CASP4) OTVQTV1L CASP4_HUMAN Increases Expression [36]
NADH dehydrogenase flavoprotein 1, mitochondrial (NDUFV1) OTEVK4WW NDUV1_HUMAN Decreases Expression [8]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Increases Phosphorylation [86]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) OTI862QH CPT1A_HUMAN Decreases Expression [49]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Increases Expression [9]
Cyclin-dependent kinase 7 (CDK7) OTAO19PQ CDK7_HUMAN Increases Activity [87]
Palmitoyl-protein thioesterase 1 (PPT1) OTM3S4DE PPT1_HUMAN Decreases Expression [49]
Dual specificity protein phosphatase 3 (DUSP3) OTPJX9B4 DUS3_HUMAN Decreases Expression [8]
Matrix metalloproteinase-16 (MMP16) OTSFQ2BJ MMP16_HUMAN Decreases Expression [36]
Caspase-5 (CASP5) OT0F2THD CASP5_HUMAN Increases Expression [36]
Cyclin-H (CCNH) OTKDU3SR CCNH_HUMAN Increases Expression [9]
Activated RNA polymerase II transcriptional coactivator p15 (SUB1) OTK71JYU TCP4_HUMAN Decreases Expression [9]
Epithelial membrane protein 3 (EMP3) OTODMJ1D EMP3_HUMAN Increases Expression [48]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Expression [36]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Expression [36]
Cadherin-11 (CDH11) OTIZKPTF CAD11_HUMAN Increases Expression [48]
Tumor protein D52 (TPD52) OTPKSK43 TPD52_HUMAN Decreases Expression [48]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Increases Cleavage [71]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) OTOWDUNT PTEN_HUMAN Increases Activity [88]
Eukaryotic initiation factor 4A-I (EIF4A1) OTMTBX6N IF4A1_HUMAN Decreases Expression [9]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Increases Expression [89]
Ras-related C3 botulinum toxin substrate 1 (RAC1) OTKRO61U RAC1_HUMAN Decreases Expression [8]
SH3 domain-binding protein 2 (SH3BP2) OT90JNBS 3BP2_HUMAN Decreases Expression [9]
General transcription factor II-I (GTF2I) OTUYL1TQ GTF2I_HUMAN Decreases Expression [8]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Increases Expression [9]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Decreases Expression [70]
Antigen peptide transporter 1 (TAP1) OTJL27PW TAP1_HUMAN Increases Expression [31]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Decreases Expression [50]
Copper-transporting ATPase 1 (ATP7A) OTMR3GXP ATP7A_HUMAN Increases Expression [31]
Protein kinase C delta type (PRKCD) OTSEH90E KPCD_HUMAN Affects Localization [60]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [11]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Decreases Expression [36]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Decreases Expression [39]
Heat shock protein beta-3 (HSPB3) OTE67YM5 HSPB3_HUMAN Increases Expression [9]
Lymphocyte cytosolic protein 2 (LCP2) OT57KE22 LCP2_HUMAN Increases Expression [9]
FAS-associated death domain protein (FADD) OTV7GFHH FADD_HUMAN Increases Expression [36]
Mitogen-activated protein kinase kinase kinase 1 (MAP3K1) OTS3FVTY M3K1_HUMAN Increases Cleavage [82]
MAGUK p55 subfamily member 3 (MPP3) OTNOL0HA MPP3_HUMAN Increases Expression [9]
Rho-associated protein kinase 1 (ROCK1) OTSXYVW1 ROCK1_HUMAN Increases Expression [8]
Short transient receptor potential channel 3 (TRPC3) OTNR61OD TRPC3_HUMAN Increases Expression [9]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 (ENPP2) OTTUU92F ENPP2_HUMAN Increases Expression [48]
Protein-tyrosine kinase 6 (PTK6) OT7NWIQ0 PTK6_HUMAN Increases Expression [8]
Interleukin-18 (IL18) OTBB2A8O IL18_HUMAN Increases Expression [57]
Protein BTG3 (BTG3) OT9ANHVT BTG3_HUMAN Increases Expression [9]
Src substrate cortactin (CTTN) OTJRG4ES SRC8_HUMAN Decreases Expression [9]
Caprin-1 (CAPRIN1) OTEJAMS3 CAPR1_HUMAN Decreases Expression [36]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Expression [36]
Periostin (POSTN) OTWP62UA POSTN_HUMAN Increases Expression [48]
Procollagen C-endopeptidase enhancer 1 (PCOLCE) OTJXOAN4 PCOC1_HUMAN Increases Expression [48]
Transcription factor E2F5 (E2F5) OT1XWING E2F5_HUMAN Increases Expression [8]
Microtubule-associated protein RP/EB family member 1 (MAPRE1) OTCVQD60 MARE1_HUMAN Decreases Localization [90]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [11]
Transcriptional regulator QRICH1 (QRICH1) OTPVAX04 QRIC1_HUMAN Increases Phosphorylation [91]
Parafibromin (CDC73) OT6JASZ1 CDC73_HUMAN Decreases Expression [36]
Inactive caspase-12 (CASP12) OTY2W6FG CASPC_HUMAN Decreases Expression [50]
Heme A synthase COX15 (COX15) OTUIYHIW COX15_HUMAN Decreases Expression [8]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) OTE8GBUR RIR2B_HUMAN Increases Expression [92]
Cell division cycle and apoptosis regulator protein 1 (CCAR1) OTUXLQZZ CCAR1_HUMAN Increases Expression [36]
NAD-dependent protein deacetylase sirtuin-2 (SIRT2) OT5Q6SVK SIR2_HUMAN Decreases Expression [54]
Abnormal spindle-like microcephaly-associated protein (ASPM) OTKXQMNA ASPM_HUMAN Increases Expression [51]
Phospholipid-transporting ATPase ABCA7 (ABCA7) OT51S50X ABCA7_HUMAN Increases Expression [31]
Centromere protein S (CENPS) OTZ4J391 CENPS_HUMAN Increases Expression [36]
NAD-dependent protein deacylase sirtuin-6 (SIRT6) OTF755ZO SIR6_HUMAN Decreases Expression [54]
Cholesterol transporter ABCA5 (ABCA5) OT4B9D92 ABCA5_HUMAN Increases Expression [31]
MAP kinase-activating death domain protein (MADD) OTUFYVGG MADD_HUMAN Decreases Expression [8]
Mucin-16 (MUC16) OTHPPE67 MUC16_HUMAN Decreases Expression [93]
Rap guanine nucleotide exchange factor 5 (RAPGEF5) OT53VS75 RPGF5_HUMAN Increases Expression [9]
Estrogen receptor beta (ESR2) OTXNR2WQ ESR2_HUMAN Decreases Expression [12]
Transcription factor AP-2 gamma (TFAP2C) OTUDIW05 AP2C_HUMAN Decreases Expression [48]
Caspase-10 (CASP10) OTE6J88E CASPA_HUMAN Increases Expression [36]
Engulfment and cell motility protein 3 (ELMO3) OTQHO9VM ELMO3_HUMAN Increases Expression [9]
p53 apoptosis effector related to PMP-22 (PERP) OTP0YL53 PERP_HUMAN Increases Expression [36]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [94]
Cell division cycle 5-like protein (CDC5L) OTTPFUU5 CDC5L_HUMAN Decreases Expression [36]
M-phase phosphoprotein 6 (MPHOSPH6) OT6E2S48 MPH6_HUMAN Decreases Expression [9]
Heterogeneous nuclear ribonucleoprotein A/B (HNRNPAB) OTUKPFOK ROAA_HUMAN Decreases Expression [8]
Transmembrane protein 243 (TMEM243) OT8NQ79G TM243_HUMAN Increases Expression [95]
Cell division cycle-associated protein 7 (CDCA7) OT12HDZY CDCA7_HUMAN Decreases Expression [36]
Transmembrane gamma-carboxyglutamic acid protein 4 (PRRG4) OT2SZQI7 TMG4_HUMAN Decreases Expression [48]
TRIO and F-actin-binding protein (TRIOBP) OTGB5WHC TARA_HUMAN Increases Expression [9]
ATP-binding cassette sub-family B member 6 (ABCB6) OTPGZFES ABCB6_HUMAN Decreases Expression [31]
Bridging integrator 3 (BIN3) OTMIWWDW BIN3_HUMAN Decreases Expression [9]
Diablo IAP-binding mitochondrial protein (DIABLO) OTHJ9MCZ DBLOH_HUMAN Increases Expression [50]
NAD-dependent protein deacetylase sirtuin-7 (SIRT7) OT5M4OT4 SIR7_HUMAN Decreases Expression [54]
Olfactomedin-like protein 3 (OLFML3) OTDN45FN OLFL3_HUMAN Increases Expression [48]
G2 and S phase-expressed protein 1 (GTSE1) OTPP742Z GTSE1_HUMAN Increases Expression [9]
ETS homologous factor (EHF) OTY6TPWD EHF_HUMAN Decreases Expression [48]
Programmed cell death 1 ligand 1 (CD274) OTJ0VFDL PD1L1_HUMAN Increases Expression [96]
DNA polymerase kappa (POLK) OTKZ38JH POLK_HUMAN Decreases Expression [8]
Protein Hook homolog 1 (HOOK1) OTTTKV7V HOOK1_HUMAN Decreases Expression [48]
PR domain zinc finger protein 4 (PRDM4) OTD9PAZJ PRDM4_HUMAN Decreases Expression [9]
F-box only protein 5 (FBXO5) OTTR957W FBX5_HUMAN Affects Expression [55]
Neurabin-1 (PPP1R9A) OTJL2TOC NEB1_HUMAN Decreases Expression [8]
Matrix metalloproteinase-17 (MMP17) OT5TMIQ6 MMP17_HUMAN Decreases Expression [36]
Microtubule-associated protein RP/EB family member 3 (MAPRE3) OTSCLETV MARE3_HUMAN Affects Localization [90]
Cyclin-D-binding Myb-like transcription factor 1 (DMTF1) OTDKO9OO DMTF1_HUMAN Decreases Expression [8]
RuvB-like 2 (RUVBL2) OTGWJ4T4 RUVB2_HUMAN Decreases Expression [9]
C-type lectin domain family 11 member A (CLEC11A) OT9KBH7C CLC11_HUMAN Increases Expression [48]
Tumor necrosis factor ligand superfamily member 13B (TNFSF13B) OTND26XR TN13B_HUMAN Increases Expression [36]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5) OT03QCLM ATF5_HUMAN Decreases Expression [8]
Protein-arginine deiminase type-2 (PADI2) OTT40K94 PADI2_HUMAN Decreases Expression [9]
Mitochondrial import inner membrane translocase subunit Tim22 (TIMM22) OTJMHX1V TIM22_HUMAN Increases Expression [9]
Small ribosomal subunit protein mS40 (MRPS18B) OT1K9PFX RT18B_HUMAN Decreases Expression [9]
Transforming acidic coiled-coil-containing protein 3 (TACC3) OTRNEZTA TACC3_HUMAN Decreases Expression [9]
Sorting nexin-10 (SNX10) OT05B7BT SNX10_HUMAN Affects Response To Substance [14]
Superoxide dismutase (SOD2) OT08HOR5 Q4ZJI1_HUMAN Increases ADR [6]
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) OT0DZGY4 E2AK3_HUMAN Affects Response To Substance [14]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Decreases Response To Substance [97]
Phospholipid phosphatase 1 (PLPP1) OT0IIMI5 PLPP1_HUMAN Decreases Response To Substance [98]
Interleukin-17 receptor B (IL17RB) OT0KDNSF I17RB_HUMAN Decreases Response To Substance [98]
Oxysterol-binding protein-related protein 10 (OSBPL10) OT0TFMBE OSB10_HUMAN Affects Response To Substance [14]
NADH dehydrogenase 1 alpha subcomplex subunit 13 (NDUFA13) OT0UOKIT NDUAD_HUMAN Affects Response To Substance [14]
Tripartite motif-containing protein 2 (TRIM2) OT0V1YVC TRIM2_HUMAN Affects Response To Substance [14]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Increases Response To Substance [99]
Condensin complex subunit 3 (NCAPG) OT1AI9EO CND3_HUMAN Affects Response To Substance [14]
Integrin beta-5 (ITGB5) OT21MF51 ITB5_HUMAN Decreases Response To Substance [34]
NADH dehydrogenase 1 beta subcomplex subunit 7 (NDUFB7) OT2CHQQ1 NDUB7_HUMAN Affects Response To Substance [14]
Aldehyde oxidase (AOX1) OT2FZP6H AOXA_HUMAN Affects Response To Substance [14]
U11/U12 small nuclear ribonucleoprotein 25 kDa protein (SNRNP25) OT2MR6O2 SNR25_HUMAN Affects Response To Substance [14]
Epidermal growth factor-like protein 6 (EGFL6) OT331X59 EGFL6_HUMAN Decreases Response To Substance [17]
Biglycan (BGN) OT3AV6IF PGS1_HUMAN Affects Response To Substance [14]
Cytidine deaminase (CDA) OT3HXP6N CDD_HUMAN Affects Response To Substance [100]
Collagen alpha-1(VII) chain (COL7A1) OT3MIRZJ CO7A1_HUMAN Increases Response To Substance [98]
Solute carrier family 12 member 2 (SLC12A2) OT3ZJ3LH S12A2_HUMAN Decreases Response To Substance [98]
NADH dehydrogenase 1 beta subcomplex subunit 2, mitochondrial (NDUFB2) OT4717TF NDUB2_HUMAN Affects Response To Substance [14]
High mobility group protein B1 (HMGB1) OT4B7CPF HMGB1_HUMAN Affects Response To Substance [14]
Deoxycytidylate deaminase (DCTD) OT4FLFT4 DCTD_HUMAN Affects Response To Substance [14]
Sorcin (SRI) OT4R3EAC SORCN_HUMAN Decreases Response To Substance [101]
Beclin-1 (BECN1) OT4X293M BECN1_HUMAN Affects Response To Substance [57]
Ubiquitin-like protein ISG15 (ISG15) OT53QQ7N ISG15_HUMAN Affects Response To Substance [14]
MARVEL domain-containing protein 1 (MARVELD1) OT5CPOJE MALD1_HUMAN Increases Response To Substance [102]
Small ribosomal subunit protein uS15m (MRPS15) OT5HRAPP RT15_HUMAN Affects Response To Substance [14]
RAC-gamma serine/threonine-protein kinase (AKT3) OT5M2LFI AKT3_HUMAN Affects Response To Substance [77]
Signal recognition particle receptor subunit alpha (SRPRA) OT5NMYTY SRPRA_HUMAN Affects Response To Substance [14]
Annexin A1 (ANXA1) OT5OFDJC ANXA1_HUMAN Increases Response To Substance [98]
Beta-sarcoglycan (SGCB) OT5R5LAT SGCB_HUMAN Affects Response To Substance [14]
Collagen alpha-2(V) chain (COL5A2) OT5VOSQE CO5A2_HUMAN Decreases Response To Substance [17]
Transmembrane protein 135 (TMEM135) OT63ZT3X TM135_HUMAN Affects Response To Substance [14]
Farnesyl pyrophosphate synthase (FDPS) OT6CKWV5 FPPS_HUMAN Increases Response To Substance [34]
Ferritin heavy chain (FTH1) OT6IFS0O FRIH_HUMAN Decreases Response To Substance [34]
DNA topoisomerase 2-alpha (TOP2A) OT6LPS08 TOP2A_HUMAN Increases Response To Substance [34]
Claudin-3 (CLDN3) OT71MN9S CLD3_HUMAN Decreases Response To Substance [98]
Plasminogen activator inhibitor 2 (SERPINB2) OT72QLZB PAI2_HUMAN Affects Response To Substance [14]
DNA-binding protein RFX5 (RFX5) OT73KJ5P RFX5_HUMAN Decreases Response To Substance [34]
CD40 ligand (CD40LG) OT75Z6A6 CD40L_HUMAN Decreases Response To Substance [103]
Large ribosomal subunit protein P1 (RPLP1) OT7B0SIB RLA1_HUMAN Decreases Response To Substance [34]
Fibroblast growth factor 2 (FGF2) OT7YUJ9F FGF2_HUMAN Decreases Response To Substance [104]
Nucleolar and spindle-associated protein 1 (NUSAP1) OT85HIJ5 NUSAP_HUMAN Affects Response To Substance [14]
Peroxisomal multifunctional enzyme type 2 (HSD17B4) OT8733D7 DHB4_HUMAN Affects Response To Substance [14]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Response To Substance [105]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) OT8KME51 BUB1B_HUMAN Affects Response To Substance [106]
Thrombomodulin (THBD) OT8VHLKY TRBM_HUMAN Decreases Response To Substance [107]
Transcriptional repressor CTCF (CTCF) OT8ZB70U CTCF_HUMAN Decreases Response To Substance [34]
Neuron navigator 3 (NAV3) OT97M1TR NAV3_HUMAN Affects Response To Substance [14]
Solute carrier family 22 member 18 (SLC22A18) OT9C3KR4 S22AI_HUMAN Decreases Response To Substance [98]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) OT9DERT1 GILT_HUMAN Decreases Response To Substance [34]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Response To Substance [34]
Beta-glucuronidase (GUSB) OT9N1DK3 BGLR_HUMAN Affects Response To Substance [14]
FXYD domain-containing ion transport regulator 3 (FXYD3) OT9PPRHE FXYD3_HUMAN Increases Response To Substance [34]
Proteasome subunit beta type-6 (PSMB6) OT9VXPNW PSB6_HUMAN Affects Response To Substance [14]
High mobility group nucleosome-binding domain-containing protein 3 (HMGN3) OTA2TBWS HMGN3_HUMAN Affects Response To Substance [14]
Atypical chemokine receptor 3 (ACKR3) OTA6GA4F ACKR3_HUMAN Decreases Response To Substance [34]
Diphosphoinositol polyphosphate phosphohydrolase NUDT4B (NUDT4) OTA6ICI2 NUD4B_HUMAN Affects Response To Substance [14]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Increases Response To Substance [108]
Proteasome subunit alpha type-4 (PSMA4) OTAD2XXI PSA4_HUMAN Affects Response To Substance [14]
POM121 and ZP3 fusion protein (POMZP3) OTAH2JOK POZP3_HUMAN Affects Response To Substance [14]
Mediator of RNA polymerase II transcription subunit 4 (MED4) OTALFN4S MED4_HUMAN Affects Response To Substance [14]
snRNA-activating protein complex subunit 1 (SNAPC1) OTAPN1NI SNPC1_HUMAN Increases Response To Substance [98]
Collagen alpha-3(VI) chain (COL6A3) OTAS6R6I CO6A3_HUMAN Affects Response To Substance [14]
MAP kinase-activated protein kinase 5 (MAPKAPK5) OTAZHPVK MAPK5_HUMAN Affects Response To Substance [14]
Desmoplakin (DSP) OTB2MOP8 DESP_HUMAN Affects Response To Substance [14]
Large ribosomal subunit protein mL40 (MRPL40) OTB2QZDY RM40_HUMAN Affects Response To Substance [14]
Large ribosomal subunit protein uL16 (RPL10) OTBHOZGC RL10_HUMAN Affects Response To Substance [14]
Prominin-1 (PROM1) OTBHV8NX PROM1_HUMAN Decreases Response To Substance [109]
Probable ATP-dependent RNA helicase DDX23 (DDX23) OTBJHS8C DDX23_HUMAN Affects Response To Substance [14]
Coatomer subunit epsilon (COPE) OTBKHBT7 COPE_HUMAN Affects Response To Substance [14]
Protein FAM3C (FAM3C) OTBR6U9G FAM3C_HUMAN Affects Response To Substance [14]
Transmembrane protein 134 (TMEM134) OTBX9H9D TM134_HUMAN Affects Response To Substance [14]
Tight junction protein ZO-3 (TJP3) OTC1K8HC ZO3_HUMAN Decreases Response To Substance [98]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Affects Response To Substance [110]
Cyclin-dependent kinase 4 inhibitor C (CDKN2C) OTCLOV90 CDN2C_HUMAN Affects Response To Substance [14]
Cytochrome c oxidase copper chaperone (COX17) OTCP4LH2 COX17_HUMAN Affects Response To Substance [14]
Trefoil factor 1 (TFF1) OTCYQH4F TFF1_HUMAN Increases Response To Substance [34]
S-phase kinase-associated protein 2 (SKP2) OTD5B41X SKP2_HUMAN Affects Response To Substance [14]
Integrin alpha-1 (ITGA1) OTDITIST ITA1_HUMAN Increases Response To Substance [17]
Stathmin (STMN1) OTDJ4RV0 STMN1_HUMAN Affects Response To Substance [111]
Gamma-adducin (ADD3) OTDRSHAZ ADDG_HUMAN Affects Response To Substance [14]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Decreases Response To Substance [34]
Superkiller complex protein 8 (SKIC8) OTDSQYDN SKI8_HUMAN Affects Response To Substance [14]
DNA-binding protein RFXANK (RFXANK) OTDX1026 RFXK_HUMAN Affects Response To Substance [14]
Transcription initiation factor TFIID subunit 1 (TAF1) OTDYS5G4 TAF1_HUMAN Affects Response To Substance [112]
EF-hand calcium-binding domain-containing protein 7 (EFCAB7) OTE0EG10 EFCB7_HUMAN Affects Response To Substance [14]
Glucose-6-phosphate isomerase (GPI) OTEGSRXG G6PI_HUMAN Affects Response To Substance [14]
GTP cyclohydrolase 1 feedback regulatory protein (GCHFR) OTEOT8GI GFRP_HUMAN Decreases Response To Substance [98]
Tyrosine-protein phosphatase non-receptor type 13 (PTPN13) OTESFZSO PTN13_HUMAN Increases Response To Substance [98]
Rho GDP-dissociation inhibitor 1 (ARHGDIA) OTEXWJDO GDIR1_HUMAN Affects Response To Substance [113]
Caveolin-1 (CAV1) OTEZUR1L CAV1_HUMAN Increases Response To Substance [34]
Serglycin (SRGN) OTFAVSX0 SRGN_HUMAN Affects Response To Substance [14]
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PIK3C2A) OTFBU4GD P3C2A_HUMAN Affects Response To Substance [14]
Laminin subunit alpha-2 (LAMA2) OTFROQWE LAMA2_HUMAN Increases Response To Substance [17]
Squalene synthase (FDFT1) OTGDISIT FDFT_HUMAN Affects Response To Substance [14]
Cytotoxic granule associated RNA binding protein TIA1 (TIA1) OTGPN3P8 TIA1_HUMAN Affects Response To Substance [14]
Stanniocalcin-1 (STC1) OTGVVXYF STC1_HUMAN Affects Response To Substance [14]
Gasdermin-D (GSDMD) OTH39BKI GSDMD_HUMAN Affects Response To Substance [57]
Low-density lipoprotein receptor (LDLR) OTH559LU LDLR_HUMAN Affects Response To Substance [14]
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Increases Response To Substance [16]
Catalase (CAT) OTHEBX9R CATA_HUMAN Increases Response To Substance [114]
Metallothionein-2 (MT2A) OTHOACHD MT2_HUMAN Increases Response To Substance [34]
Neurogenic locus notch homolog protein 1 (NOTCH1) OTI1WADQ NOTC1_HUMAN Decreases Response To Substance [115]
Interstitial collagenase (MMP1) OTI4I2V1 MMP1_HUMAN Affects Response To Substance [14]
G2/mitotic-specific cyclin-B2 (CCNB2) OTIEXTDK CCNB2_HUMAN Affects Response To Substance [14]
Polycystin-2 (PKD2) OTIXBU8H PKD2_HUMAN Increases Response To Substance [98]
G/T mismatch-specific thymine DNA glycosylase (TDG) OTJB0YIH TDG_HUMAN Affects Response To Substance [14]
E3 ubiquitin-protein ligase FANCL (FANCL) OTJC7QPQ FANCL_HUMAN Affects Response To Substance [14]
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1 (PLCE1) OTJISZOX PLCE1_HUMAN Decreases Response To Substance [98]
Transmembrane protein 168 (TMEM168) OTJKZ6G9 TM168_HUMAN Affects Response To Substance [14]
Plakophilin-2 (PKP2) OTJOVF68 PKP2_HUMAN Decreases Response To Substance [98]
C-X-C chemokine receptor type 6 (CXCR6) OTK9R50G CXCR6_HUMAN Decreases Response To Substance [34]
Tyrosine-protein kinase receptor UFO (AXL) OTKA2SUX UFO_HUMAN Increases Response To Substance [98]
NADH dehydrogenase 1 alpha subcomplex subunit 1 (NDUFA1) OTKBUQXP NDUA1_HUMAN Affects Response To Substance [14]
CCN family member 1 (CCN1) OTKJBEMD CCN1_HUMAN Increases Response To Substance [98]
Serine/threonine-protein kinase PLK2 (PLK2) OTKMJXJ8 PLK2_HUMAN Increases ADR [6]
Galectin-4 (LGALS4) OTKQCG0H LEG4_HUMAN Decreases Response To Substance [98]
Methylsterol monooxygenase 1 (MSMO1) OTKV62RZ MSMO1_HUMAN Affects Response To Substance [14]
Leukocyte surface antigen CD47 (CD47) OTLDZ0KZ CD47_HUMAN Decreases Response To Substance [34]
Pyruvate kinase PKM (PKM) OTLHHMC2 KPYM_HUMAN Affects Response To Substance [14]
Transcription factor E2F1 (E2F1) OTLKYBBC E2F1_HUMAN Increases Response To Substance [99]
Glutathione S-transferase P (GSTP1) OTLP0A0Y GSTP1_HUMAN Increases Response To Substance [16]
Peptidyl-prolyl cis-trans isomerase B (PPIB) OTLPH6KN PPIB_HUMAN Affects Response To Substance [14]
Annexin A8 (ANXA8) OTLSSQCY ANXA8_HUMAN Increases Response To Substance [98]
Keratin, type II cytoskeletal 7 (KRT7) OTLT3JFN K2C7_HUMAN Increases Response To Substance [98]
Lysosome-associated membrane glycoprotein 2 (LAMP2) OTLUGEJC LAMP2_HUMAN Affects Response To Substance [14]
Peroxiredoxin-2 (PRDX2) OTLWCY9T PRDX2_HUMAN Affects Response To Substance [14]
Hemicentin-1 (HMCN1) OTLZAS0P HMCN1_HUMAN Increases Response To Substance [17]
Furin (FURIN) OTM2665Z FURIN_HUMAN Decreases Response To Substance [34]
NADH dehydrogenase iron-sulfur protein 8, mitochondrial (NDUFS8) OTMEAWKO NDUS8_HUMAN Affects Response To Substance [14]
Probable dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase (ALG8) OTMFG2YY ALG8_HUMAN Affects Response To Substance [14]
Glutathione S-transferase Mu 5 (GSTM5) OTMMBFY8 GSTM5_HUMAN Decreases Response To Substance [34]
Unconventional myosin-Va (MYO5A) OTMWLP3E MYO5A_HUMAN Increases Response To Substance [98]
Integral membrane protein 2B (ITM2B) OTMXEPXB ITM2B_HUMAN Affects Response To Substance [14]
Succinate--CoA ligase subunit beta, mitochondrial (SUCLA2) OTMZD4PW SUCB1_HUMAN Affects Response To Substance [14]
Four and a half LIM domains protein 1 (FHL1) OTN535SU FHL1_HUMAN Increases Response To Substance [98]
L-lactate dehydrogenase A chain (LDHA) OTN7K4XB LDHA_HUMAN Increases Response To Substance [116]
Proto-oncogene serine/threonine-protein kinase mos (MOS) OTNMQPFJ MOS_HUMAN Increases ADR [6]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Increases ADR [6]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1) OTNYXOZO KCMA1_HUMAN Affects Response To Substance [14]
G-protein coupled receptor 35 (GPR35) OTO23NRK GPR35_HUMAN Decreases Response To Substance [98]
Histone deacetylase 9 (HDAC9) OTO8O0LF HDAC9_HUMAN Increases Response To Substance [98]
Receptor tyrosine-protein kinase erbB-2 (ERBB2) OTOAUNCK ERBB2_HUMAN Decreases Response To Substance [117]
Arginine/serine-rich protein 1 (RSRP1) OTOAZLCL RSRP1_HUMAN Affects Response To Substance [14]
Malectin (MLEC) OTOPGRF5 MLEC_HUMAN Affects Response To Substance [14]
Oncostatin-M-specific receptor subunit beta (OSMR) OTORWHPL OSMR_HUMAN Increases Response To Substance [98]
E3 ubiquitin-protein ligase Mdm2 (MDM2) OTOVXARF MDM2_HUMAN Decreases Response To Substance [118]
Delta(24)-sterol reductase (DHCR24) OTP301JW DHC24_HUMAN Affects Response To Substance [14]
Interleukin-13 receptor subunit alpha-2 (IL13RA2) OTPC2G0X I13R2_HUMAN Affects Response To Substance [14]
DNA dC->dU-editing enzyme APOBEC-3C (APOBEC3C) OTPL0AI1 ABC3C_HUMAN Affects Response To Substance [14]
Prostaglandin E synthase 3 (PTGES3) OTPPQWI0 TEBP_HUMAN Affects Response To Substance [14]
Large ribosomal subunit protein uL23 (RPL23A) OTPYLCCX RL23A_HUMAN Decreases Response To Substance [34]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Increases Response To Substance [34]
Eukaryotic translation initiation factor 5A-1 (EIF5A) OTQ8DJX5 IF5A1_HUMAN Increases Response To Substance [98]
Membrane cofactor protein (CD46) OTQ8NWJD MCP_HUMAN Increases Response To Substance [34]
Glutamine--fructose-6-phosphate aminotransferase 1 (GFPT1) OTQBDO45 GFPT1_HUMAN Decreases Response To Substance [98]
Clusterin (CLU) OTQGG0JM CLUS_HUMAN Decreases Response To Substance [119]
MAPK/MAK/MRK overlapping kinase (MOK) OTQK7M9V MOK_HUMAN Affects Response To Substance [14]
Keratin, type I cytoskeletal 23 (KRT23) OTQW6UAG K1C23_HUMAN Increases Response To Substance [17]
Fibroblast growth factor 5 (FGF5) OTQXGHBY FGF5_HUMAN Affects Response To Substance [14]
Solute carrier family 22 member 3 (SLC22A3) OTQYGVXX S22A3_HUMAN Affects Response To Substance [14]
Nuclear body protein SP140 (SP140) OTQZHFMT SP140_HUMAN Affects Response To Substance [14]
Transforming growth factor-beta-induced protein ig-h3 (TGFBI) OTR443C5 BGH3_HUMAN Decreases Response To Substance [17]
E3 ubiquitin-protein ligase CHFR (CHFR) OTRAD2TT CHFR_HUMAN Decreases Response To Substance [120]
Large ribosomal subunit protein mL63 (MRPL57) OTRB659E RT63_HUMAN Affects Response To Substance [14]
Protein CREG1 (CREG1) OTRHJ8HK CREG1_HUMAN Affects Response To Substance [14]
Acidic leucine-rich nuclear phosphoprotein 32 family member A (ANP32A) OTRHPFO2 AN32A_HUMAN Affects Response To Substance [14]
Retinol-binding protein 1 (RBP1) OTRP1MFC RET1_HUMAN Increases Response To Substance [98]
Receptor tyrosine-protein kinase erbB-3 (ERBB3) OTRSST0A ERBB3_HUMAN Decreases Response To Substance [98]
Aldo-keto reductase family 1 member B1 (AKR1B1) OTRX72TH ALDR_HUMAN Increases Response To Substance [98]
Arrestin-C (ARR3) OTRZ00CH ARRC_HUMAN Decreases Response To Substance [34]
MHC class I polypeptide-related sequence B (MICB) OTS2DVDW MICB_HUMAN Increases Response To Substance [98]
Latent-transforming growth factor beta-binding protein 2 (LTBP2) OTS88GSD LTBP2_HUMAN Affects Response To Substance [14]
Calcium/calmodulin-dependent protein kinase type II subunit beta (CAMK2B) OTS9YK3E KCC2B_HUMAN Affects Response To Substance [14]
Lumican (LUM) OTSRC874 LUM_HUMAN Decreases Response To Substance [17]
Rhotekin (RTKN) OTSS8XR6 RTKN_HUMAN Decreases Response To Substance [121]
3-phosphoinositide-dependent protein kinase 1 (PDPK1) OTT09ZVP PDPK1_HUMAN Decreases Response To Substance [105]
Plasminogen activator inhibitor 1 (SERPINE1) OTT0MPQ3 PAI1_HUMAN Affects Response To Substance [14]
Collagen alpha-1(III) chain (COL3A1) OTT1EMLM CO3A1_HUMAN Decreases Response To Substance [17]
Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF) OTT5JX1F LITAF_HUMAN Affects Response To Substance [14]
Nucleophosmin (NPM1) OTTBYYT0 NPM_HUMAN Decreases Response To Substance [122]
Amyloid beta precursor like protein 2 (APLP2) OTTFE53M APLP2_HUMAN Affects Response To Substance [14]
Collagen alpha-1(XV) chain (COL15A1) OTTFKK18 COFA1_HUMAN Decreases Response To Substance [17]
Fascin (FSCN1) OTTGIHTM FSCN1_HUMAN Increases Response To Substance [98]
Keratin, type I cytoskeletal 13 (KRT13) OTTYSKGX K1C13_HUMAN Decreases Response To Substance [34]
Annexin A4 (ANXA4) OTUCRYXL ANXA4_HUMAN Decreases Response To Substance [123]
C-X-C chemokine receptor type 4 (CXCR4) OTUFSBX2 CXCR4_HUMAN Decreases Response To Substance [34]
N-acetylgalactosaminyltransferase 7 (GALNT7) OTUJSCAO GALT7_HUMAN Affects Response To Substance [14]
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1 (DAD1) OTUUNQBT DAD1_HUMAN Increases ADR [6]
Mitochondrial Rho GTPase 2 (RHOT2) OTV8WT2L MIRO2_HUMAN Affects Response To Substance [14]
Matrilin-2 (MATN2) OTVDR68G MATN2_HUMAN Decreases Response To Substance [17]
NADPH--cytochrome P450 reductase (POR) OTVIDOCH NCPR_HUMAN Increases Response To Substance [16]
Integrin beta-1-binding protein 1 (ITGB1BP1) OTVQFNGS ITBP1_HUMAN Affects Response To Substance [14]
U2 small nuclear ribonucleoprotein A' (SNRPA1) OTWJZFAP RU2A_HUMAN Affects Response To Substance [14]
Decorin (DCN) OTWLJL7K PGS2_HUMAN Decreases Response To Substance [17]
Glypican-3 (GPC3) OTWS8WSW GPC3_HUMAN Increases Response To Substance [17]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Decreases Response To Substance [124]
Transmembrane protein 59 (TMEM59) OTX4EKES TMM59_HUMAN Affects Response To Substance [14]
Nucleotide triphosphate diphosphatase NUDT15 (NUDT15) OTX8SZOT NUD15_HUMAN Affects Response To Substance [14]
Metallothionein-1E (MT1E) OTXJKU4Y MT1E_HUMAN Increases Response To Substance [34]
NADH dehydrogenase 1 alpha subcomplex subunit 3 (NDUFA3) OTXL10N9 NDUA3_HUMAN Affects Response To Substance [14]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1) OTXNGZCG MD2L1_HUMAN Affects Response To Substance [106]
Neuroendocrine protein 7B2 (SCG5) OTXSJMT1 7B2_HUMAN Affects Response To Substance [14]
Peripheral myelin protein 22 (PMP22) OTXWYWCZ PMP22_HUMAN Decreases Response To Substance [34]
Collagen alpha-2(I) chain (COL1A2) OTY7G382 CO1A2_HUMAN Increases Response To Substance [17]
Bone morphogenetic protein 7 (BMP7) OTYATP2K BMP7_HUMAN Increases Response To Substance [34]
Serine/threonine-protein phosphatase PP1-beta catalytic subunit (PPP1CB) OTYFTYFR PP1B_HUMAN Affects Response To Substance [14]
Ferritin light chain (FTL) OTYQA8A6 FRIL_HUMAN Decreases Response To Substance [34]
Proteasome subunit beta type-1 (PSMB1) OTYRFBAH PSB1_HUMAN Affects Response To Substance [14]
Procathepsin L (CTSL) OTYTUW29 CATL1_HUMAN Increases Response To Substance [34]
ADP-ribosylation factor 3 (ARF3) OTYYQX85 ARF3_HUMAN Affects Response To Substance [14]
V-type proton ATPase catalytic subunit A (ATP6V1A) OTYZ2S9E VATA_HUMAN Affects Response To Substance [14]
Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) OTYZQJD3 TIM13_HUMAN Affects Response To Substance [14]
Erythropoietin (EPO) OTZ90CN4 EPO_HUMAN Decreases Response To Substance [125]
Tissue factor pathway inhibitor 2 (TFPI2) OTZCRWOR TFPI2_HUMAN Affects Response To Substance [14]
Insulin-induced gene 1 protein (INSIG1) OTZF5X1D INSI1_HUMAN Affects Response To Substance [14]
C-X-C motif chemokine 5 (CXCL5) OTZOUPCA CXCL5_HUMAN Affects Response To Substance [14]
------------------------------------------------------------------------------------
⏷ Show the Full List of 478 DOT(s)
Indication(s) of Bortezomib
Disease Entry ICD 11 Status REF
Leukemia N.A. Approved [3]
Lung cancer 2C25.0 Approved [3]
Lymphoproliferative syndrome N.A. Approved [3]
MALT lymphoma N.A. Approved [3]
Mantle cell lymphoma 2A85.5 Approved [4]
Minimally invasive lung adenocarcinoma N.A. Approved [3]
Multiple myeloma 2A83 Approved [5]
Nodal marginal zone lymphoma 2A85.0 Approved [3]
Plasma cell myeloma 2A83.1 Approved [3]
Recurrent adult burkitt lymphoma 2A85.6 Approved [3]
Non-hodgkin lymphoma 2B33.5 Phase 3 [5]
B-cell neoplasm N.A. Investigative [3]
Colon cancer 2B90.Z Investigative [3]
Gastric cancer 2B72 Investigative [3]
Bortezomib Interacts with 3 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Cationic trypsinogen (PRSS1) TT2WR1T TRY1_HUMAN Inhibitor [132]
Kallikrein-related peptidase (KLK) TT5L2VC NOUNIPROTAC Inhibitor [132]
Proteasome (PS) TTU7ZMG NOUNIPROTAC Modulator [133]
------------------------------------------------------------------------------------
Bortezomib Interacts with 1 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [134]
------------------------------------------------------------------------------------
Bortezomib Interacts with 5 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [135]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Metabolism [136]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Metabolism [137]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Metabolism [138]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Metabolism [137]
------------------------------------------------------------------------------------
Bortezomib Interacts with 686 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Decreases Expression [139]
Extended synaptotagmin-2 (ESYT2) OTWCXTX3 ESYT2_HUMAN Decreases Expression [126]
Alternative prion protein (PRNP) OTE85L1Q APRIO_HUMAN Increases Expression [126]
Serine/threonine-protein kinase Sgk1 (SGK1) OT301T1U SGK1_HUMAN Increases Expression [126]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) OT7C68YV BACH_HUMAN Decreases Expression [126]
GTP-binding protein 1 (GTPBP1) OTA9KV6C GTPB1_HUMAN Decreases Expression [126]
Galectin-8 (LGALS8) OT71LJ8T LEG8_HUMAN Increases Expression [126]
26S proteasome non-ATPase regulatory subunit 12 (PSMD12) OTWICA51 PSD12_HUMAN Increases Expression [126]
Leukocyte-specific transcript 1 protein (LST1) OTUVG424 LST1_HUMAN Decreases Expression [126]
Agrin (AGRN) OTWJENAZ AGRIN_HUMAN Decreases Expression [126]
Krev interaction trapped protein 1 (KRIT1) OT58AP1I KRIT1_HUMAN Increases Expression [126]
Beta-1,3-N-acetylglucosaminyltransferase manic fringe (MFNG) OTUX45ZF MFNG_HUMAN Decreases Expression [126]
Pirin (PIR) OT8ALXHU PIR_HUMAN Increases Expression [126]
Pyridoxal kinase (PDXK) OT40AJ5J PDXK_HUMAN Increases Expression [126]
Stearoyl-CoA desaturase (SCD) OTB1073G SCD_HUMAN Decreases Expression [126]
Suppressor of cytokine signaling 3 (SOCS3) OTY183WJ SOCS3_HUMAN Increases Expression [126]
TRAF-type zinc finger domain-containing protein 1 (TRAFD1) OT7AU2R3 TRAD1_HUMAN Increases Expression [126]
Cytoplasmic dynein 1 intermediate chain 1 (DYNC1I1) OTFX1KCG DC1I1_HUMAN Increases Expression [126]
Chromodomain-helicase-DNA-binding protein 2 (CHD2) OTRKL6YC CHD2_HUMAN Increases Expression [126]
Golgi SNAP receptor complex member 2 (GOSR2) OTYHIYN2 GOSR2_HUMAN Increases Expression [126]
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10) OTOKUXUH ADA10_HUMAN Decreases Expression [126]
Apolipoprotein L1 (APOL1) OT8QBVTY APOL1_HUMAN Increases Expression [126]
Interferon-inducible protein AIM2 (AIM2) OT86QUI8 AIM2_HUMAN Increases Expression [126]
Myosin regulatory light chain 12B (MYL12B) OTXMLQOT ML12B_HUMAN Increases Expression [126]
Centrosomal protein of 290 kDa (CEP290) OTVN52VH CE290_HUMAN Increases Expression [126]
Small ribosomal subunit protein uS12m (MRPS12) OTGY4GIX RT12_HUMAN Decreases Expression [126]
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (OGT) OT1Z1ZXE OGT1_HUMAN Decreases Expression [126]
V-type proton ATPase subunit e 1 (ATP6V0E1) OTZZIUYY VA0E1_HUMAN Increases Expression [126]
ATP-binding cassette sub-family C member 4 (ABCC4) OTO27PAL MRP4_HUMAN Decreases Expression [126]
Transcription factor MafG (MAFG) OTBQFUZH MAFG_HUMAN Increases Expression [126]
Interleukin-1 receptor-associated kinase-like 2 (IRAK2) OT6Y1QZN IRAK2_HUMAN Increases Expression [126]
PHD finger protein 1 (PHF1) OTW2PSIR PHF1_HUMAN Increases Expression [126]
Synaptogyrin-2 (SYNGR2) OTJX84RI SNG2_HUMAN Decreases Expression [126]
Cytohesin-interacting protein (CYTIP) OTRJ3ZC5 CYTIP_HUMAN Increases Expression [126]
Growth arrest-specific protein 7 (GAS7) OT0M5TNY GAS7_HUMAN Decreases Expression [126]
F-box-like/WD repeat-containing protein TBL1X (TBL1X) OTXQ51E0 TBL1X_HUMAN Increases Expression [126]
Glycosaminoglycan xylosylkinase (FAM20B) OTOA0UYT XYLK_HUMAN Decreases Expression [126]
Suppressor of cytokine signaling 5 (SOCS5) OTN1ABYR SOCS5_HUMAN Increases Expression [126]
Protein tyrosine phosphatase type IVA 3 (PTP4A3) OTXMMWUN TP4A3_HUMAN Decreases Expression [126]
Deformed epidermal autoregulatory factor 1 homolog (DEAF1) OTCLX3ZW DEAF1_HUMAN Decreases Expression [126]
Calpain-15 (CAPN15) OT0WE161 CAN15_HUMAN Decreases Expression [126]
Carbonyl reductase 3 (CBR3) OT9G6SF0 CBR3_HUMAN Increases Expression [126]
Triple functional domain protein (TRIO) OT71X1AK TRIO_HUMAN Decreases Expression [126]
Cystatin-F (CST7) OTQWZUVQ CYTF_HUMAN Increases Expression [126]
ATP-dependent DNA helicase Q4 (RECQL4) OT59LSW7 RECQ4_HUMAN Increases Expression [126]
Erlin-2 (ERLIN2) OT551BVG ERLN2_HUMAN Decreases Expression [126]
Pre-mRNA-processing factor 6 (PRPF6) OT3U0ABN PRP6_HUMAN Decreases Expression [126]
Lysine-specific demethylase 4B (KDM4B) OT5P1UPY KDM4B_HUMAN Decreases Expression [126]
Methyl-CpG-binding domain protein 4 (MBD4) OTWR9YXE MBD4_HUMAN Increases Expression [126]
Arginyl-tRNA--protein transferase 1 (ATE1) OT3QNM39 ATE1_HUMAN Increases Expression [126]
GDH/6PGL endoplasmic bifunctional protein (H6PD) OTO7TNDD G6PE_HUMAN Decreases Expression [126]
NAD kinase (NADK) OTYN9GX0 NADK_HUMAN Decreases Expression [126]
AP-2 complex subunit alpha-1 (AP2A1) OTEFZB21 AP2A1_HUMAN Decreases Expression [126]
Mitogen-activated protein kinase kinase kinase kinase 4 (MAP4K4) OTBMJUOC M4K4_HUMAN Increases Expression [126]
Acyl-CoA 6-desaturase (FADS2) OTUX531P FADS2_HUMAN Decreases Expression [126]
Phosphatidylserine lipase ABHD16A (ABHD16A) OTDS9K1Z ABHGA_HUMAN Increases Expression [126]
G patch domain and ankyrin repeat-containing protein 1 (GPANK1) OT1TN2KT GPAN1_HUMAN Increases Expression [126]
Putative lipid scramblase CLPTM1 (CLPTM1) OT14QP7N CLPT1_HUMAN Decreases Expression [126]
Glutathione reductase, mitochondrial (GSR) OTM2TUYM GSHR_HUMAN Increases Expression [126]
HLA class II histocompatibility antigen, DR alpha chain (HLA-DRA) OT7KZMP2 DRA_HUMAN Decreases Expression [126]
Myelin basic protein (MBP) OTFZCEDB MBP_HUMAN Decreases Expression [126]
Thy-1 membrane glycoprotein (THY1) OTVONVTB THY1_HUMAN Decreases Expression [126]
HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1) OTW8JHU2 DPB1_HUMAN Decreases Expression [126]
T-cell surface glycoprotein CD5 (CD5) OTC5JEG5 CD5_HUMAN Decreases Expression [126]
Alpha-galactosidase A (GLA) OTBSR6DT AGAL_HUMAN Increases Expression [126]
HLA class II histocompatibility antigen, DO alpha chain (HLA-DOA) OTZE5Q7R DOA_HUMAN Decreases Expression [126]
Cathepsin D (CTSD) OTQZ36F3 CATD_HUMAN Increases Expression [126]
Trypsin-2 (PRSS2) OTOMVUWL TRY2_HUMAN Decreases Expression [126]
Prosaposin (PSAP) OTUOEKY7 SAP_HUMAN Increases Expression [126]
Guanine nucleotide-binding protein G(i) subunit alpha-3 (GNAI3) OT89UWAR GNAI3_HUMAN Increases Expression [126]
Steryl-sulfatase (STS) OTXTJQPC STS_HUMAN Decreases Expression [126]
Monoacylglycerol lipase ABHD2 (ABHD2) OTCRUOCS ABHD2_HUMAN Increases Expression [126]
Gamma-enolase (ENO2) OTRODL0T ENOG_HUMAN Increases Expression [126]
Tropomyosin alpha-1 chain (TPM1) OTD73X6R TPM1_HUMAN Increases Expression [126]
Cancer/testis antigen family 45 member A6 (CT45A5) OTIFETOM CT456_HUMAN Increases Expression [126]
Schwannomin-interacting protein 1 (SCHIP1) OTF3FR4A SCHI1_HUMAN Decreases Expression [126]
Granzyme B (GZMB) OTPPVIRS GRAB_HUMAN Increases Expression [126]
Clusterin (CLU) OTQGG0JM CLUS_HUMAN Increases Expression [126]
Endoplasmic reticulum chaperone BiP (HSPA5) OTFUIRAO BIP_HUMAN Increases Expression [126]
Phenylethanolamine N-methyltransferase (PNMT) OTGLCPE8 PNMT_HUMAN Decreases Expression [126]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) OT2HZK5M GTR3_HUMAN Increases Expression [126]
Ras-related protein Ral-A (RALA) OT734R7X RALA_HUMAN Increases Expression [126]
Breakpoint cluster region protein (BCR) OTCN76C1 BCR_HUMAN Decreases Expression [126]
Glucose-6-phosphate 1-dehydrogenase (G6PD) OT300SMK G6PD_HUMAN Decreases Expression [126]
Steroid hormone receptor ERR1 (ESRRA) OTTDTUSP ERR1_HUMAN Decreases Expression [126]
B-cell antigen receptor complex-associated protein alpha chain (CD79A) OTOJC8DV CD79A_HUMAN Decreases Expression [126]
Granzyme A (GZMA) OT43R33L GRAA_HUMAN Decreases Expression [126]
Cytochrome b-245 light chain (CYBA) OT16N9ZO CY24A_HUMAN Decreases Expression [126]
Sodium/potassium-transporting ATPase subunit alpha-3 (ATP1A3) OTM8EG6H AT1A3_HUMAN Decreases Expression [126]
Perforin-1 (PRF1) OTFVXD7H PERF_HUMAN Decreases Expression [126]
Insulin-degrading enzyme (IDE) OT5GQTJ5 IDE_HUMAN Increases Expression [126]
Ras-related C3 botulinum toxin substrate 2 (RAC2) OTAOHFNH RAC2_HUMAN Decreases Expression [126]
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A (GSPT1) OT18H1B0 ERF3A_HUMAN Decreases Expression [126]
Folate receptor alpha (FOLR1) OT0QZ0H6 FOLR1_HUMAN Decreases Expression [126]
Cyclic AMP-dependent transcription factor ATF-2 (ATF2) OTNIZPEA ATF2_HUMAN Increases Expression [126]
NAD(P)H dehydrogenase 1 (NQO1) OTZGGIVK NQO1_HUMAN Increases Expression [126]
Immunoglobulin lambda-like polypeptide 1 (IGLL1) OTRTNVOG IGLL1_HUMAN Decreases Expression [126]
Mucin-1 (MUC1) OTHQI7IY MUC1_HUMAN Decreases Expression [126]
Ribosyldihydronicotinamide dehydrogenase (NQO2) OTGDAJRZ NQO2_HUMAN Increases Expression [126]
Leukosialin (SPN) OTFW338K LEUK_HUMAN Decreases Expression [126]
Transcription factor JunD (JUND) OTNKACJD JUND_HUMAN Decreases Expression [126]
Integrin beta-6 (ITGB6) OTI3DJ7U ITB6_HUMAN Increases Expression [126]
Ras-related protein Rab-5A (RAB5A) OTFR2KM4 RAB5A_HUMAN Decreases Expression [126]
Integrin alpha-L (ITGAL) OTCUQAIS ITAL_HUMAN Decreases Expression [126]
B-cell lymphoma 3 protein (BCL3) OT1M5B95 BCL3_HUMAN Decreases Expression [126]
5'-nucleotidase (NT5E) OT7J5LT6 5NTD_HUMAN Decreases Expression [126]
Ephrin type-A receptor 1 (EPHA1) OTGJMRZ0 EPHA1_HUMAN Decreases Expression [126]
CD9 antigen (CD9) OT2184XU CD9_HUMAN Increases Expression [126]
Integrin alpha-6 (ITGA6) OT3FA39C ITA6_HUMAN Decreases Expression [126]
Ribosomal protein S6 kinase beta-1 (RPS6KB1) OTAELNGX KS6B1_HUMAN Increases Expression [126]
Tyrosine-protein kinase JAK1 (JAK1) OT0X3D17 JAK1_HUMAN Decreases Expression [126]
ER lumen protein-retaining receptor 1 (KDELR1) OT8YBS5G ERD21_HUMAN Decreases Expression [126]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [126]
Polypyrimidine tract-binding protein 1 (PTBP1) OT2OBJUK PTBP1_HUMAN Decreases Expression [126]
NKG2-D type II integral membrane protein (KLRK1) OTQWXK71 NKG2D_HUMAN Decreases Expression [126]
CD82 antigen (CD82) OTH8MC64 CD82_HUMAN Decreases Expression [126]
HLA class II histocompatibility antigen, DM beta chain (HLA-DMB) OT17HGXJ DMB_HUMAN Decreases Expression [126]
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 (CD38) OTG0TTX7 CD38_HUMAN Decreases Expression [126]
Ephrin type-B receptor 2 (EPHB2) OT8VZ6C5 EPHB2_HUMAN Decreases Expression [126]
Flavin reductase (BLVRB) OTHCFN2C BLVRB_HUMAN Increases Expression [126]
G1/S-specific cyclin-D2 (CCND2) OTDULQF9 CCND2_HUMAN Decreases Expression [126]
Homeobox protein Hox-A11 (HOXA11) OT42C4HF HXA11_HUMAN Decreases Expression [126]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Increases Expression [126]
Stress-induced-phosphoprotein 1 (STIP1) OT7TXLOX STIP1_HUMAN Decreases Expression [126]
Guanylate-binding protein 2 (GBP2) OTVU4G07 GBP2_HUMAN Increases Expression [126]
Multidrug resistance-associated protein 1 (ABCC1) OTGUN89S MRP1_HUMAN Decreases Expression [126]
Protein phosphatase 1A (PPM1A) OT1U770U PPM1A_HUMAN Increases Expression [126]
Transcription factor 7 (TCF7) OT1ID822 TCF7_HUMAN Decreases Expression [126]
Dual specificity mitogen-activated protein kinase kinase 2 (MAP2K2) OTUE7Z91 MP2K2_HUMAN Decreases Expression [126]
Transgelin-2 (TAGLN2) OTUXZGDQ TAGL2_HUMAN Decreases Expression [126]
Pre-B-cell leukemia transcription factor 3 (PBX3) OT8WMVM4 PBX3_HUMAN Decreases Expression [126]
Interleukin-15 (IL15) OTQSYWQS IL15_HUMAN Increases Expression [126]
Trifunctional enzyme subunit alpha, mitochondrial (HADHA) OTO557N2 ECHA_HUMAN Increases Expression [126]
Eukaryotic translation initiation factor 2 subunit 3 (EIF2S3) OTARRES9 IF2G_HUMAN Decreases Expression [126]
B-cell lymphoma 6 protein (BCL6) OTQAWWO1 BCL6_HUMAN Increases Expression [126]
Lysine-specific demethylase 5C (KDM5C) OTZ6E0HY KDM5C_HUMAN Decreases Expression [126]
Eukaryotic translation initiation factor 1 (EIF1) OTB4GZ0V EIF1_HUMAN Increases Expression [126]
5-hydroxytryptamine receptor 2B (HTR2B) OTM1AD9J 5HT2B_HUMAN Decreases Expression [126]
Lamina-associated polypeptide 2, isoform alpha (TMPO) OTL68EL4 LAP2A_HUMAN Decreases Expression [126]
ETS translocation variant 4 (ETV4) OT8C98UZ ETV4_HUMAN Decreases Expression [126]
Killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4) OT00N6UJ KI2S4_HUMAN Decreases Expression [126]
26S proteasome regulatory subunit 6B (PSMC4) OTS3XN41 PRS6B_HUMAN Increases Expression [126]
Lys-63-specific deubiquitinase BRCC36 (BRCC3) OTK0ZN7Y BRCC3_HUMAN Decreases Expression [126]
LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1) OT729S0T LIMS1_HUMAN Increases Expression [126]
NADP-dependent malic enzyme (ME1) OTSVEUQE MAOX_HUMAN Increases Expression [126]
MAP kinase-activated protein kinase 2 (MAPKAPK2) OT460SBO MAPK2_HUMAN Decreases Expression [126]
Large ribosomal subunit protein bL19m (MRPL19) OTRBKF6R RM19_HUMAN Increases Expression [126]
Beta-arrestin-1 (ARRB1) OT2NJS37 ARRB1_HUMAN Decreases Expression [126]
Ubiquitin-conjugating enzyme E2 R1 (CDC34) OTNBK390 UB2R1_HUMAN Increases Expression [126]
Choline-phosphate cytidylyltransferase A (PCYT1A) OTMH0YLN PCY1A_HUMAN Increases Expression [126]
Protein phosphatase 1F (PPM1F) OTU0MVR7 PPM1F_HUMAN Increases Expression [126]
Protein numb homolog (NUMB) OTMB586Q NUMB_HUMAN Increases Expression [126]
Presenilin-1 (PSEN1) OTKL39RT PSN1_HUMAN Decreases Expression [126]
Cytosolic purine 5'-nucleotidase (NT5C2) OTJMF66Z 5NTC_HUMAN Increases Expression [126]
DNA ligase 4 (LIG4) OT40DNXU DNLI4_HUMAN Increases Expression [126]
Dynamin-2 (DNM2) OTUYU2U3 DYN2_HUMAN Decreases Expression [126]
Poly(A) polymerase alpha (PAPOLA) OTPHD65D PAPOA_HUMAN Decreases Expression [126]
Tyrosine-protein kinase Blk (BLK) OT1EB8MT BLK_HUMAN Decreases Expression [126]
Succinate-semialdehyde dehydrogenase, mitochondrial (ALDH5A1) OTF3TBTK SSDH_HUMAN Decreases Expression [126]
26S proteasome non-ATPase regulatory subunit 7 (PSMD7) OT7PZZ4K PSMD7_HUMAN Increases Expression [126]
N-sulphoglucosamine sulphohydrolase (SGSH) OTLSSEOS SPHM_HUMAN Increases Expression [126]
AF4/FMR2 family member 1 (AFF1) OTT2C78E AFF1_HUMAN Increases Expression [126]
Importin subunit alpha-1 (KPNA2) OTU7FOE6 IMA1_HUMAN Increases Expression [126]
Diacylglycerol kinase epsilon (DGKE) OTWS86AS DGKE_HUMAN Decreases Expression [126]
Dual specificity mitogen-activated protein kinase kinase 6 (MAP2K6) OTK13JKC MP2K6_HUMAN Decreases Expression [126]
Rho GDP-dissociation inhibitor 1 (ARHGDIA) OTEXWJDO GDIR1_HUMAN Decreases Expression [126]
Cysteine-rich protein 2 (CRIP2) OTVVJSYX CRIP2_HUMAN Decreases Expression [126]
Serine/threonine-protein phosphatase 5 (PPP5C) OTC3HT6Y PPP5_HUMAN Decreases Expression [126]
Delta-1-pyrroline-5-carboxylate synthase (ALDH18A1) OT6W40XU P5CS_HUMAN Decreases Expression [126]
Proteinase-activated receptor 2 (F2RL1) OTMRMJ8N PAR2_HUMAN Decreases Expression [126]
Myc-associated zinc finger protein (MAZ) OTEHKN1M MAZ_HUMAN Decreases Expression [126]
ADP-ribosylation factor-like protein 4C (ARL4C) OTQ3QNNU ARL4C_HUMAN Decreases Expression [126]
Small integral membrane protein 11 (SMIM11) OTZPLVUC SIM11_HUMAN Decreases Expression [126]
Triosephosphate isomerase (TPI1) OT14KP4B TPIS_HUMAN Increases Expression [126]
Cell division control protein 42 homolog (CDC42) OT5QBC5M CDC42_HUMAN Decreases Expression [126]
C-X-C chemokine receptor type 4 (CXCR4) OTUFSBX2 CXCR4_HUMAN Decreases Expression [126]
Large ribosomal subunit protein uL24 (RPL26) OTFNRC27 RL26_HUMAN Increases Expression [126]
cAMP-dependent protein kinase inhibitor alpha (PKIA) OT8M5GVO IPKA_HUMAN Increases Expression [126]
AP-1 complex subunit sigma-1A (AP1S1) OTQ2H8DN AP1S1_HUMAN Decreases Expression [126]
Small ribosomal subunit protein uS17 (RPS11) OTILZE44 RS11_HUMAN Increases Expression [126]
ADP-ribosylation factor 6 (ARF6) OTVV7KJO ARF6_HUMAN Increases Expression [126]
Peptidyl-prolyl cis-trans isomerase FKBP1A (FKBP1A) OT6285L4 FKB1A_HUMAN Decreases Expression [126]
Calcineurin subunit B type 1 (PPP3R1) OTGQNFJQ CANB1_HUMAN Decreases Expression [126]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) OT9297OG 2ABA_HUMAN Increases Expression [126]
Small ubiquitin-related modifier 1 (SUMO1) OTJFD4P5 SUMO1_HUMAN Increases Expression [126]
Eukaryotic translation initiation factor 5A-1 (EIF5A) OTQ8DJX5 IF5A1_HUMAN Decreases Expression [126]
DNA-dependent protein kinase catalytic subunit (PRKDC) OTJVS4EG PRKDC_HUMAN Decreases Expression [126]
Small ribosomal subunit protein uS5m (MRPS5) OTZZR208 RT05_HUMAN Decreases Expression [126]
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) OTOVM4D4 SPTB2_HUMAN Increases Expression [126]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Decreases Expression [126]
2-oxoglutarate dehydrogenase complex component E1 (OGDH) OTHGTQWF ODO1_HUMAN Decreases Expression [126]
Methylmalonate-semialdehyde/malonate-semialdehyde dehydrogenase , mitochondrial (ALDH6A1) OT8LCZCT MMSA_HUMAN Decreases Expression [126]
Mitochondrial 2-oxoglutarate/malate carrier protein (SLC25A11) OT7EVFBK M2OM_HUMAN Decreases Expression [126]
Glutathione S-transferase Mu 4 (GSTM4) OTOTF8DU GSTM4_HUMAN Decreases Expression [126]
cAMP-responsive element modulator (CREM) OTJIJ5AL CREM_HUMAN Increases Expression [126]
Centromere protein C (CENPC) OTVJ6VE9 CENPC_HUMAN Increases Expression [126]
Transcription factor p65 (RELA) OTUJP9CN TF65_HUMAN Decreases Expression [126]
Neurogenic locus notch homolog protein 2 (NOTCH2) OTQ3Y9PA NOTC2_HUMAN Decreases Expression [126]
CTD small phosphatase-like protein 2 (CTDSPL2) OTPF8W4P CTSL2_HUMAN Decreases Expression [126]
Tyrosine-protein phosphatase non-receptor type 11 (PTPN11) OTFH9M73 PTN11_HUMAN Decreases Expression [126]
Early activation antigen CD69 (CD69) OTGJHSVP CD69_HUMAN Increases Expression [126]
Serine/arginine-rich splicing factor 1 (SRSF1) OTF61HOV SRSF1_HUMAN Decreases Expression [126]
Rho GTPase-activating protein 1 (ARHGAP1) OT0H2ZBZ RHG01_HUMAN Decreases Expression [126]
FACT complex subunit SSRP1 (SSRP1) OT5TYJK9 SSRP1_HUMAN Decreases Expression [126]
Sodium/bile acid cotransporter 7 (SLC10A7) OTYLAWNV NTCP7_HUMAN Increases Expression [126]
Apolipoprotein B receptor (APOBR) OT9EUZX3 APOBR_HUMAN Decreases Expression [126]
Nuclear factor 1 A-type (NFIA) OTDHQ9CG NFIA_HUMAN Decreases Expression [126]
Interferon-related developmental regulator 2 (IFRD2) OT2URF18 IFRD2_HUMAN Decreases Expression [126]
Protein AF1q (MLLT11) OTG5RVHC AF1Q_HUMAN Increases Expression [126]
PR domain zinc finger protein 2 (PRDM2) OT8L7CGX PRDM2_HUMAN Decreases Expression [126]
Dual specificity protein phosphatase 4 (DUSP4) OT6WAO12 DUS4_HUMAN Decreases Expression [126]
Oxysterols receptor LXR-alpha (NR1H3) OT54YZ9I NR1H3_HUMAN Decreases Expression [126]
Chromobox protein homolog 3 (CBX3) OTOP9RLD CBX3_HUMAN Increases Expression [126]
Phosducin-like protein (PDCL) OTDNHIXG PHLP_HUMAN Increases Expression [126]
DNA-binding protein Ikaros (IKZF1) OTCW1FKL IKZF1_HUMAN Decreases Expression [126]
Protein OS-9 (OS9) OTB5B2TY OS9_HUMAN Increases Expression [126]
Peptidyl-prolyl cis-trans isomerase FKBP5 (FKBP5) OT404F9K FKBP5_HUMAN Decreases Expression [126]
Sequestosome-1 (SQSTM1) OTGY5D5J SQSTM_HUMAN Increases Expression [126]
Transformer-2 protein homolog alpha (TRA2A) OT5NHOO3 TRA2A_HUMAN Decreases Expression [126]
Rap guanine nucleotide exchange factor 1 (RAPGEF1) OTZ0TBN1 RPGF1_HUMAN Decreases Expression [126]
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A (PDE7A) OTVDV4IT PDE7A_HUMAN Decreases Expression [126]
Nuclear transcription factor Y subunit gamma (NFYC) OTZVVEV7 NFYC_HUMAN Decreases Expression [126]
Transcription factor Dp-1 (TFDP1) OT6RZ7VT TFDP1_HUMAN Decreases Expression [126]
Fas-activated serine/threonine kinase (FASTK) OTTHFZMP FASTK_HUMAN Decreases Expression [126]
Mediator of DNA damage checkpoint protein 1 (MDC1) OTEUQH4J MDC1_HUMAN Decreases Expression [126]
Structural maintenance of chromosomes protein 1A (SMC1A) OT9ZMRK9 SMC1A_HUMAN Decreases Expression [126]
Neutral alpha-glucosidase AB (GANAB) OTYLXY4M GANAB_HUMAN Decreases Expression [126]
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PPP2R5D) OT43TTX0 2A5D_HUMAN Decreases Expression [126]
Kinesin-like protein KIF22 (KIF22) OTY6X6BL KIF22_HUMAN Decreases Expression [126]
Killer cell immunoglobulin-like receptor 3DS1 (KIR3DS1) OTJWIO4T KI3S1_HUMAN Decreases Expression [126]
Killer cell immunoglobulin-like receptor 2DS3 (KIR2DS3) OT3PSLDL KI2S3_HUMAN Decreases Expression [126]
DAZ-associated protein 2 (DAZAP2) OTNURO9F DAZP2_HUMAN Decreases Expression [126]
Neutrophil cytosol factor 4 (NCF4) OTX007YL NCF4_HUMAN Decreases Expression [126]
kinase isozyme 2, mitochondrial (PDK2) OTM436F9 PDK2_HUMAN Decreases Expression [126]
Leucine-rich repeat-containing protein 41 (LRRC41) OT4YSBV5 LRC41_HUMAN Decreases Expression [126]
Ras suppressor protein 1 (RSU1) OTO5GHT1 RSU1_HUMAN Increases Expression [126]
Scaffold attachment factor B1 (SAFB) OTGRV2LW SAFB1_HUMAN Decreases Expression [126]
NF-kappa-B inhibitor beta (NFKBIB) OTY1ZJXH IKBB_HUMAN Increases Expression [126]
NGFI-A-binding protein 2 (NAB2) OTG4BDF3 NAB2_HUMAN Decreases Expression [126]
Neuronal pentraxin-1 (NPTX1) OTKVHCV0 NPTX1_HUMAN Decreases Expression [126]
Coiled-coil domain-containing protein 6 (CCDC6) OTXRQDYG CCDC6_HUMAN Decreases Expression [126]
Drebrin (DBN1) OTZVKG8A DREB_HUMAN Increases Expression [126]
Solute carrier family 35 member G1 (SLC35G1) OTKZUA8O S35G1_HUMAN Decreases Expression [126]
Protein mono-ADP-ribosyltransferase PARP6 (PARP6) OTWSXW4O PARP6_HUMAN Decreases Expression [126]
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) OTN7XAUD LRRF1_HUMAN Increases Expression [126]
Polycomb group RING finger protein 3 (PCGF3) OTY7TPPZ PCGF3_HUMAN Increases Expression [126]
NAD kinase 2, mitochondrial (NADK2) OT1I8GDE NAKD2_HUMAN Increases Expression [126]
B-cell CLL/lymphoma 7 protein family member A (BCL7A) OTYFUJTP BCL7A_HUMAN Decreases Expression [126]
Glycerol-3-phosphate acyltransferase 3 (GPAT3) OTJUGPK0 GPAT3_HUMAN Increases Expression [126]
Acylglycerol kinase, mitochondrial (AGK) OTJGWBYT AGK_HUMAN Decreases Expression [126]
Vesicle transport protein SFT2C (SFT2D3) OT0IEAAR SFT2C_HUMAN Decreases Expression [126]
Transmembrane protein 41B (TMEM41B) OTW0B0KS TM41B_HUMAN Increases Expression [126]
Torsin-1A-interacting protein 1 (TOR1AIP1) OTTG8MAK TOIP1_HUMAN Decreases Expression [126]
Tetratricopeptide repeat protein 39A (TTC39A) OT80PQWX TT39A_HUMAN Increases Expression [126]
Protein furry homolog (FRY) OT74IAG2 FRY_HUMAN Increases Expression [126]
Probable E3 ubiquitin-protein ligase HECTD2 (HECTD2) OTDIBGQV HECD2_HUMAN Increases Expression [126]
G-protein coupled receptor 157 (GPR157) OTE7K9D7 GP157_HUMAN Decreases Expression [126]
Obscurin (OBSCN) OTT14OVX OBSCN_HUMAN Decreases Expression [126]
G kinase-anchoring protein 1 (GKAP1) OTHZRJ56 GKAP1_HUMAN Increases Expression [126]
Protein TASOR 2 (TASOR2) OTN4VE8H TASO2_HUMAN Decreases Expression [126]
Sushi domain-containing protein 4 (SUSD4) OTWCJTT3 SUSD4_HUMAN Decreases Expression [126]
Proteasome adapter and scaffold protein ECM29 (ECPAS) OT1C0KOI ECM29_HUMAN Increases Expression [126]
DENN domain-containing protein 4C (DENND4C) OT8SYN47 DEN4C_HUMAN Increases Expression [126]
Pecanex-like protein 4 (PCNX4) OTV474RQ PCX4_HUMAN Increases Expression [126]
Protein SPT2 homolog (SPTY2D1) OT1RY99Z SPT2_HUMAN Increases Expression [126]
CWF19-like protein 1 (CWF19L1) OTAMYTOW C19L1_HUMAN Decreases Expression [126]
U11/U12 small nuclear ribonucleoprotein 48 kDa protein (SNRNP48) OTSR6DEJ SNR48_HUMAN Increases Expression [126]
Tyrosine-protein kinase STYK1 (STYK1) OT61CSU7 STYK1_HUMAN Increases Expression [126]
SPRY domain-containing SOCS box protein 3 (SPSB3) OTHGEE2K SPSB3_HUMAN Increases Expression [126]
E3 ubiquitin-protein ligase TRIM65 (TRIM65) OTSQTK3A TRI65_HUMAN Decreases Expression [126]
Leucine-rich repeat and fibronectin type-III domain-containing protein 4 (LRFN4) OT7RWBKE LRFN4_HUMAN Decreases Expression [126]
Type-1 angiotensin II receptor-associated protein (AGTRAP) OT02N7LD ATRAP_HUMAN Decreases Expression [126]
Transmembrane protein 92 (TMEM92) OTTKJ2C0 TMM92_HUMAN Decreases Expression [126]
MICOS complex subunit MIC27 (APOOL) OTC1WT8O MIC27_HUMAN Increases Expression [126]
DnaJ homolog subfamily C member 14 (DNAJC14) OT7DPIVN DJC14_HUMAN Decreases Expression [126]
TBC1 domain family member 9 (TBC1D9) OTSSCTB5 TBCD9_HUMAN Increases Expression [126]
Ras-associated and pleckstrin homology domains-containing protein 1 (RAPH1) OTMQXW7S RAPH1_HUMAN Increases Expression [126]
Serine/threonine-protein kinase MARK2 (MARK2) OTJWGLUZ MARK2_HUMAN Decreases Expression [126]
Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B) OTE8GBUR RIR2B_HUMAN Increases Expression [126]
Probable C-mannosyltransferase DPY19L4 (DPY19L4) OTQ89TXA D19L4_HUMAN Increases Expression [126]
Coiled-coil domain-containing protein 186 (CCDC186) OTONSQAD CC186_HUMAN Increases Expression [126]
C-myc promoter-binding protein (DENND4A) OT8FFZ29 MYCPP_HUMAN Increases Expression [126]
Cytochrome P450 2U1 (CYP2U1) OT6RXLXS CP2U1_HUMAN Increases Expression [126]
HAUS augmin-like complex subunit 6 (HAUS6) OT7ZVR57 HAUS6_HUMAN Increases Expression [126]
Type 1 phosphatidylinositol 4,5-bisphosphate 4-phosphatase (PIP4P1) OT991XS0 PP4P1_HUMAN Decreases Expression [126]
Kinectin (KTN1) OTQAV541 KTN1_HUMAN Increases Expression [126]
Phosphatidylcholine:ceramide cholinephosphotransferase 1 (SGMS1) OTZQE7PW SMS1_HUMAN Increases Expression [126]
Sodium-independent sulfate anion transporter (SLC26A11) OTWBV9CR S2611_HUMAN Increases Expression [126]
RNA-binding protein MEX3D (MEX3D) OTAUWRK7 MEX3D_HUMAN Decreases Expression [126]
Dynein axonemal assembly factor 5 (DNAAF5) OTN0CT52 DAAF5_HUMAN Decreases Expression [126]
Syntaxin-12 (STX12) OT5IBQ62 STX12_HUMAN Increases Expression [126]
Mitogen-activated protein kinase kinase kinase kinase 3 (MAP4K3) OTNJX38T M4K3_HUMAN Increases Expression [126]
Protein FAM219A (FAM219A) OTAFZHY9 F219A_HUMAN Increases Expression [126]
Mitofusin-1 (MFN1) OTCBXQZF MFN1_HUMAN Decreases Expression [126]
Pleckstrin homology domain-containing family M member 2 (PLEKHM2) OT4ZYV73 PKHM2_HUMAN Decreases Expression [126]
Mitochondrial Rho GTPase 2 (RHOT2) OTV8WT2L MIRO2_HUMAN Decreases Expression [126]
Xaa-Arg dipeptidase (PM20D2) OTD2Y7LU P20D2_HUMAN Increases Expression [126]
Solute carrier family 38 member 6 (SLC38A6) OTIC8SHQ S38A6_HUMAN Increases Expression [126]
Abl interactor 1 (ABI1) OT5H4M62 ABI1_HUMAN Increases Expression [126]
N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2) OTRUIMC4 GNT2A_HUMAN Increases Expression [126]
Protein FAM43A (FAM43A) OT5RPQRE FA43A_HUMAN Decreases Expression [126]
CAP-Gly domain-containing linker protein 4 (CLIP4) OT75KVQK CLIP4_HUMAN Increases Expression [126]
Putative transporter SVOPL (SVOPL) OTJ4G2ND SVOPL_HUMAN Decreases Expression [126]
Polypeptide N-acetylgalactosaminyltransferase 4 (GALNT4) OT6WKC13 GALT4_HUMAN Increases Expression [126]
Coiled-coil domain-containing protein 82 (CCDC82) OT16EAZ7 CCD82_HUMAN Increases Expression [126]
SH2 domain-containing protein 3C (SH2D3C) OTAGXO0N SH2D3_HUMAN Decreases Expression [126]
Methyltransferase-like protein 27 (METTL27) OTOF0GTU MET27_HUMAN Decreases Expression [126]
ADP-ribosylation factor GTPase-activating protein 1 (ARFGAP1) OTM3KHIE ARFG1_HUMAN Decreases Expression [126]
Protein KRI1 homolog (KRI1) OT1IGOK7 KRI1_HUMAN Increases Expression [126]
ATPase family gene 2 protein homolog A (AFG2A) OTPZKWN7 AFG2A_HUMAN Increases Expression [126]
Equilibrative nucleobase transporter 1 (SLC43A3) OTR60ZLA S43A3_HUMAN Decreases Expression [126]
Retinol dehydrogenase 13 (RDH13) OT48VJ65 RDH13_HUMAN Increases Expression [126]
Neuropilin and tolloid-like protein 2 (NETO2) OT0YAMC0 NETO2_HUMAN Decreases Expression [126]
Polyhomeotic-like protein 3 (PHC3) OTTTLIAP PHC3_HUMAN Increases Expression [126]
Glutathione S-transferase C-terminal domain-containing protein (GSTCD) OTIIINMT GSTCD_HUMAN Decreases Expression [126]
Folliculin (FLCN) OTVM78XM FLCN_HUMAN Increases Expression [126]
Tubulin--tyrosine ligase (TTL) OTSS1CK4 TTL_HUMAN Decreases Expression [126]
Protein NEDD1 (NEDD1) OTBD6X77 NEDD1_HUMAN Increases Expression [126]
Protein FAM76A (FAM76A) OT28WHO4 FA76A_HUMAN Increases Expression [126]
Proline-rich protein 7 (PRR7) OT56XAQK PRR7_HUMAN Decreases Expression [126]
Transmembrane protein 254 (TMEM254) OTGDPU8S TM254_HUMAN Decreases Expression [126]
Retinol dehydrogenase 11 (RDH11) OTIND43N RDH11_HUMAN Increases Expression [126]
POC1 centriolar protein homolog B (POC1B) OTDIMIRZ POC1B_HUMAN Increases Expression [126]
Interferon-induced protein 44 (IFI44) OTOKSZVA IFI44_HUMAN Increases Expression [126]
Large ribosomal subunit protein uL30m (MRPL30) OT26OPYV RM30_HUMAN Decreases Expression [126]
RB1-inducible coiled-coil protein 1 (RB1CC1) OTZK8PFX RBCC1_HUMAN Increases Expression [126]
Elongator complex protein 5 (ELP5) OTW5R7YD ELP5_HUMAN Decreases Expression [126]
DDB1- and CUL4-associated factor 11 (DCAF11) OTNSGYK1 DCA11_HUMAN Decreases Expression [126]
Arginine/serine-rich protein PNISR (PNISR) OTUM02FW PNISR_HUMAN Increases Expression [126]
General transcription factor 3C polypeptide 2 (GTF3C2) OTWDANLJ TF3C2_HUMAN Decreases Expression [126]
Transmembrane protein 263 (TMEM263) OTO1RSTS TM263_HUMAN Increases Expression [126]
Protein THEM6 (THEM6) OT51SVLH THEM6_HUMAN Decreases Expression [126]
Pleckstrin homology-like domain family A member 1 (PHLDA1) OTFTWMIQ PHLA1_HUMAN Increases Expression [126]
Hexosaminidase D (HEXD) OTTMQKLM HEXD_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase RNF138 (RNF138) OTPU0CO4 RN138_HUMAN Increases Expression [126]
Heterogeneous nuclear ribonucleoprotein L-like (HNRNPLL) OTA6Q5E0 HNRLL_HUMAN Increases Expression [126]
Uncharacterized protein C4orf3 (C4ORF3) OT6TFN1O CD003_HUMAN Decreases Expression [126]
tRNA-splicing endonuclease subunit Sen15 (TSEN15) OT14UW31 SEN15_HUMAN Decreases Expression [126]
Palladin (PALLD) OTZ2MUJZ PALLD_HUMAN Increases Expression [126]
Protein N-lysine methyltransferase METTL21A (METTL21A) OTXJTNXY MT21A_HUMAN Increases Expression [126]
Histone acetyltransferase KAT6B (KAT6B) OTMUDTAH KAT6B_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase rififylin (RFFL) OT85MGDH RFFL_HUMAN Increases Expression [126]
Aquaporin-3 (AQP3) OT2J7JPD AQP3_HUMAN Increases Expression [126]
Proteasome inhibitor PI31 subunit (PSMF1) OTX84WLQ PSMF1_HUMAN Decreases Expression [126]
Protein FAM168A (FAM168A) OTDXQCS5 F168A_HUMAN Increases Expression [126]
Protein NDRG1 (NDRG1) OTVO66BO NDRG1_HUMAN Increases Expression [126]
TRAF family member-associated NF-kappa-B activator (TANK) OTZSGFIK TANK_HUMAN Increases Expression [126]
Ras-related protein Rab-8B (RAB8B) OTBPUHV9 RAB8B_HUMAN Decreases Expression [126]
GTP-binding protein Rit1 (RIT1) OTVNOGOH RIT1_HUMAN Increases Expression [126]
Phosphorylase b kinase regulatory subunit beta (PHKB) OTKXZZIU KPBB_HUMAN Increases Expression [126]
BLOC-2 complex member HPS3 (HPS3) OTAKROK7 HPS3_HUMAN Decreases Expression [126]
F-box/WD repeat-containing protein 7 (FBXW7) OTJXE4OT FBXW7_HUMAN Decreases Expression [126]
Polyamine deacetylase HDAC10 (HDAC10) OTHCKKUQ HDA10_HUMAN Decreases Expression [126]
NXPE family member 3 (NXPE3) OTLVZ8W2 NXPE3_HUMAN Increases Expression [126]
Transmembrane protein 230 (TMEM230) OTAFALFV TM230_HUMAN Decreases Expression [126]
SOSS complex subunit B2 (NABP1) OTFTNFHW SOSB2_HUMAN Increases Expression [126]
Ankyrin repeat domain-containing protein 9 (ANKRD9) OT7VGO6G ANKR9_HUMAN Increases Expression [126]
ADP-ribosylation factor-like protein 8A (ARL8A) OTEYM6FA ARL8A_HUMAN Increases Expression [126]
m7GpppX diphosphatase (DCPS) OT1FZVC9 DCPS_HUMAN Decreases Expression [126]
Protein FAM241B (FAM241B) OTLISLRC F241B_HUMAN Increases Expression [126]
R3H domain-containing protein 4 (R3HDM4) OTE0Q78Q R3HD4_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase CHFR (CHFR) OTRAD2TT CHFR_HUMAN Decreases Expression [126]
ATP-dependent DNA helicase DDX11 (DDX11) OT1WR3MD DDX11_HUMAN Decreases Expression [126]
Kelch domain-containing protein 7B (KLHDC7B) OT2H5BNX KLD7B_HUMAN Increases Expression [126]
H/ACA ribonucleoprotein complex non-core subunit NAF1 (NAF1) OTMJKJAK NAF1_HUMAN Increases Expression [126]
Histone-lysine N-methyltransferase EHMT2 (EHMT2) OTC4DWB6 EHMT2_HUMAN Decreases Expression [126]
Uncharacterized protein C9orf85 (C9ORF85) OTJWBPL3 CI085_HUMAN Increases Expression [126]
Pannexin-2 (PANX2) OTAQ2S8R PANX2_HUMAN Increases Expression [126]
Ribosomal protein S6 kinase delta-1 (RPS6KC1) OT2LRTG4 KS6C1_HUMAN Increases Expression [126]
Structural maintenance of chromosomes protein 6 (SMC6) OT3IBHQD SMC6_HUMAN Increases Expression [126]
Protein orai-2 (ORAI2) OTYISRYH ORAI2_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase RING2 (RNF2) OTFPLOIN RING2_HUMAN Increases Expression [126]
Krueppel-like factor 6 (KLF6) OTQY9S7F KLF6_HUMAN Increases Expression [126]
Succinate dehydrogenase cytochrome b560 subunit, mitochondrial (SDHC) OTC8G2MX C560_HUMAN Decreases Expression [126]
Sigma non-opioid intracellular receptor 1 (SIGMAR1) OTDORW5C SGMR1_HUMAN Decreases Expression [126]
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1A) OTVTB5R5 PI51A_HUMAN Decreases Expression [126]
Apolipoprotein L4 (APOL4) OTTOH86V APOL4_HUMAN Decreases Expression [126]
Protein NipSnap homolog 1 (NIPSNAP1) OTKXKUT8 NIPS1_HUMAN Decreases Expression [126]
Protein FAM118B (FAM118B) OTRLY4B0 F118B_HUMAN Increases Expression [126]
Target of rapamycin complex 2 subunit MAPKAP1 (MAPKAP1) OTYKB9G3 SIN1_HUMAN Decreases Expression [126]
TM2 domain-containing protein 3 (TM2D3) OT6MS96W TM2D3_HUMAN Increases Expression [126]
Ferroptosis suppressor protein 1 (AIFM2) OT57XWXO FSP1_HUMAN Increases Expression [126]
Tubulin-specific chaperone D (TBCD) OTS4JKNQ TBCD_HUMAN Decreases Expression [126]
Iron-sulfur cluster assembly 1 homolog, mitochondrial (ISCA1) OTU230MC ISCA1_HUMAN Increases Expression [126]
Bublin coiled-coil protein (BBLN) OTUMVEWE BBLN_HUMAN Decreases Expression [126]
Coiled-coil domain-containing protein 32 (CCDC32) OTPPUFIF CCD32_HUMAN Increases Expression [126]
Kinesin-like protein KIFC1 (KIFC1) OTNQDS00 KIFC1_HUMAN Decreases Expression [126]
Katanin p60 ATPase-containing subunit A-like 1 (KATNAL1) OTBUZ7KA KATL1_HUMAN Increases Expression [126]
Protein C1orf43 (C1ORF43) OTT9CVZR CA043_HUMAN Decreases Expression [126]
TM2 domain-containing protein 2 (TM2D2) OTB51WEY TM2D2_HUMAN Increases Expression [126]
Sphingosine-1-phosphate phosphatase 1 (SGPP1) OT9X54CQ SGPP1_HUMAN Increases Expression [126]
FSD1-like protein (FSD1L) OTBQ48RF FSD1L_HUMAN Increases Expression [126]
C-type lectin domain family 7 member A (CLEC7A) OTRTBH27 CLC7A_HUMAN Increases Expression [126]
Serrate RNA effector molecule homolog (SRRT) OTMYPSWV SRRT_HUMAN Decreases Expression [126]
Protein kinase C and casein kinase substrate in neurons protein 1 (PACSIN1) OT07Z2RQ PACN1_HUMAN Increases Expression [126]
Sterile alpha motif domain-containing protein 10 (SAMD10) OTBKWB5C SAM10_HUMAN Decreases Expression [126]
ATP-binding cassette sub-family A member 2 (ABCA2) OTVSYK0X ABCA2_HUMAN Decreases Expression [126]
INO80 complex subunit B (INO80B) OTSHV8JF IN80B_HUMAN Decreases Expression [126]
Uncharacterized protein C6orf62 (C6ORF62) OTGK4G35 CF062_HUMAN Increases Expression [126]
Gamma-aminobutyric acid receptor-associated protein-like 1 (GABARAPL1) OT4U7SBG GBRL1_HUMAN Increases Expression [126]
Nuclear ubiquitous casein and cyclin-dependent kinase substrate 1 (NUCKS1) OTL4VJC5 NUCKS_HUMAN Decreases Expression [126]
Oxysterol-binding protein-related protein 2 (OSBPL2) OTCK671N OSBL2_HUMAN Increases Expression [126]
Dual specificity protein phosphatase 15 (DUSP15) OTS6PQYL DUS15_HUMAN Decreases Expression [126]
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 3 (KCTD10) OT5HFZXU BACD3_HUMAN Increases Expression [126]
UPF0696 protein C11orf68 (C11ORF68) OTOKOGZ6 CK068_HUMAN Decreases Expression [126]
Differentially expressed in FDCP 6 homolog (DEF6) OTIRBYVK DEFI6_HUMAN Decreases Expression [126]
Sentrin-specific protease 3 (SENP3) OTFQDOMC SENP3_HUMAN Decreases Expression [126]
ESF1 homolog (ESF1) OTHEDM0A ESF1_HUMAN Increases Expression [126]
RNA polymerase II-associated protein 3 (RPAP3) OTCW17LF RPAP3_HUMAN Increases Expression [126]
Sin3 histone deacetylase corepressor complex component SDS3 (SUDS3) OTZ1AARI SDS3_HUMAN Increases Expression [126]
Caspase activity and apoptosis inhibitor 1 (CAAP1) OTD2DN1Z CAAP1_HUMAN Increases Expression [126]
Kinesin-like protein KIF9 (KIF9) OT7W6VI1 KIF9_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase SMURF2 (SMURF2) OT3TRVL7 SMUF2_HUMAN Increases Expression [126]
Transcription factor IIIB 50 kDa subunit (BRF2) OT2C6TH2 BRF2_HUMAN Increases Expression [126]
Retinoid-inducible serine carboxypeptidase (SCPEP1) OT43LYEZ RISC_HUMAN Increases Expression [126]
POZ-, AT hook-, and zinc finger-containing protein 1 (PATZ1) OT0X9WGR PATZ1_HUMAN Decreases Expression [126]
DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G) OT410VP5 ABC3G_HUMAN Increases Expression [126]
DnaJ homolog subfamily C member 4 (DNAJC4) OT4BUBQU DNJC4_HUMAN Decreases Expression [126]
DNA-directed DNA/RNA polymerase mu (POLM) OT0SRIP4 DPOLM_HUMAN Decreases Expression [126]
Carbohydrate sulfotransferase 11 (CHST11) OTNJJ5Q1 CHSTB_HUMAN Decreases Expression [126]
Uncharacterized protein C14orf132 (C14ORF132) OTBVC3AO CN132_HUMAN Decreases Expression [126]
Putative RNA-binding protein Luc7-like 1 (LUC7L) OT77JDB7 LUC7L_HUMAN Increases Expression [126]
Prefoldin subunit 4 (PFDN4) OT5NRHER PFD4_HUMAN Increases Expression [126]
Solute carrier family 35 member C2 (SLC35C2) OT9H15XZ S35C2_HUMAN Decreases Expression [126]
Gephyrin (GPHN) OTAKK1SV GEPH_HUMAN Decreases Expression [126]
Endophilin-B2 (SH3GLB2) OTF7BB9S SHLB2_HUMAN Decreases Expression [126]
Muscleblind-like protein 1 (MBNL1) OTOV7J85 MBNL1_HUMAN Decreases Expression [126]
CDC42 small effector protein 2 (CDC42SE2) OT8SG9I1 C42S2_HUMAN Decreases Expression [126]
RNA-binding protein PNO1 (PNO1) OT010GIS PNO1_HUMAN Increases Expression [126]
DDB1- and CUL4-associated factor 13 (DCAF13) OTQQ0QXT DCA13_HUMAN Increases Expression [126]
FGFR1 oncogene partner 2 (FGFR1OP2) OTAHO1ZC FGOP2_HUMAN Increases Expression [126]
DNA-directed RNA polymerase III subunit RPC5 (POLR3E) OT69PWBM RPC5_HUMAN Increases Expression [126]
Anoctamin-10 (ANO10) OTG3BNOU ANO10_HUMAN Increases Expression [126]
BSD domain-containing protein 1 (BSDC1) OT853CP9 BSDC1_HUMAN Increases Expression [126]
G patch domain-containing protein 2-like (GPATCH2L) OTETUZ64 GPT2L_HUMAN Increases Expression [126]
Ceroid-lipofuscinosis neuronal protein 6 (CLN6) OT91IAYT CLN6_HUMAN Decreases Expression [126]
AFG2-interacting ribosome maturation factor (AIRIM) OTGG814L AIRIM_HUMAN Increases Expression [126]
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2 (B3GNT2) OTE69HV8 B3GN2_HUMAN Decreases Expression [126]
Opioid growth factor receptor (OGFR) OTROS6RJ OGFR_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase KCMF1 (KCMF1) OTVTKFAU KCMF1_HUMAN Increases Expression [126]
Stromal interaction molecule 2 (STIM2) OTYNXAW0 STIM2_HUMAN Decreases Expression [126]
Inhibitor of Bruton tyrosine kinase (IBTK) OTB2GM4G IBTK_HUMAN Increases Expression [126]
Phosphatidylinositol 4-kinase beta (PI4KB) OTI9UQSU PI4KB_HUMAN Decreases Expression [126]
E3 ubiquitin-protein ligase RNF14 (RNF14) OTWX0D0H RNF14_HUMAN Increases Expression [126]
Fibulin-5 (FBLN5) OTLVNZ8U FBLN5_HUMAN Decreases Expression [126]
Beta-1,4-galactosyltransferase 6 (B4GALT6) OTBM8F2U B4GT6_HUMAN Increases Expression [126]
LIM domain-containing protein 1 (LIMD1) OTN1CG6R LIMD1_HUMAN Increases Expression [126]
Protein NDRG3 (NDRG3) OTJTJCHD NDRG3_HUMAN Decreases Expression [126]
LIM domain and actin-binding protein 1 (LIMA1) OTONPC9R LIMA1_HUMAN Increases Expression [126]
AF4/FMR2 family member 4 (AFF4) OTTL5Y8R AFF4_HUMAN Increases Expression [126]
NADH-cytochrome b5 reductase 1 (CYB5R1) OTMDHMLA NB5R1_HUMAN Increases Expression [126]
Methyl-CpG-binding domain protein 1 (MBD1) OTD19VO6 MBD1_HUMAN Decreases Expression [126]
Oxidative stress-induced growth inhibitor 1 (OSGIN1) OT9KIVZW OSGI1_HUMAN Increases Expression [126]
Cell division cycle protein 23 homolog (CDC23) OTC4O83E CDC23_HUMAN Increases Expression [126]
Anaphase-promoting complex subunit 5 (ANAPC5) OTGTJNNR APC5_HUMAN Decreases Expression [126]
Calcipressin-3 (RCAN3) OTTS3CQA RCAN3_HUMAN Decreases Expression [126]
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1 (ASAP1) OT4DLRYY ASAP1_HUMAN Decreases Expression [126]
Tetratricopeptide repeat protein 7A (TTC7A) OTDHLPQM TTC7A_HUMAN Decreases Expression [126]
Nucleosome assembly protein 1-like 2 (NAP1L2) OT8QI4GF NP1L2_HUMAN Increases Expression [126]
Protein PHTF1 (PHTF1) OTYCZ84A PHTF1_HUMAN Increases Expression [126]
26S proteasome non-ATPase regulatory subunit 13 (PSMD13) OTNQ351N PSD13_HUMAN Increases Expression [126]
Cytosolic carboxypeptidase 1 (AGTPBP1) OTR92JFR CBPC1_HUMAN Increases Expression [126]
Serine/threonine-protein kinase ICK (CILK1) OTWOYEYP CILK1_HUMAN Increases Expression [126]
Structural maintenance of chromosomes protein 3 (SMC3) OTWGFRHD SMC3_HUMAN Increases Expression [126]
Myotubularin-related protein 6 (MTMR6) OTQPAWI3 MTMR6_HUMAN Increases Expression [126]
Phospholipase A-2-activating protein (PLAA) OTZ7NJGA PLAP_HUMAN Increases Expression [126]
Phenylalanine--tRNA ligase alpha subunit (FARSA) OT3U1P20 SYFA_HUMAN Decreases Expression [126]
Nck-associated protein 1 (NCKAP1) OTEZQXXJ NCKP1_HUMAN Increases Expression [126]
Kelch-like protein 20 (KLHL20) OTC0SFS9 KLH20_HUMAN Increases Expression [126]
ARF GTPase-activating protein GIT1 (GIT1) OTHO92S5 GIT1_HUMAN Decreases Expression [126]
RING finger protein 11 (RNF11) OTFBJSKQ RNF11_HUMAN Increases Expression [126]
Transformation/transcription domain-associated protein (TRRAP) OT68OI2Y TRRAP_HUMAN Decreases Expression [126]
Carbohydrate sulfotransferase 2 (CHST2) OTV11IZF CHST2_HUMAN Decreases Expression [126]
G-protein-signaling modulator 3 (GPSM3) OT2MO458 GPSM3_HUMAN Decreases Expression [126]
U6 snRNA-associated Sm-like protein LSm4 (LSM4) OTLKJB3A LSM4_HUMAN Decreases Expression [126]
DNA-directed RNA polymerase III subunit RPC8 (POLR3H) OT7GM7MX RPC8_HUMAN Decreases Expression [126]
NEDD8 ultimate buster 1 (NUB1) OTWA6RTX NUB1_HUMAN Increases Expression [126]
Selenoprotein K (SELENOK) OTKM7N7P SELK_HUMAN Increases Expression [126]
Nuclear receptor coactivator 3 (NCOA3) OTBX300Z NCOA3_HUMAN Increases Expression [126]
Numb-like protein (NUMBL) OTWMTMMH NUMBL_HUMAN Increases Expression [126]
ATPase MORC2 (MORC2) OT52A8BJ MORC2_HUMAN Increases Expression [126]
Aldo-keto reductase family 1 member B10 (AKR1B10) OTOA4HTH AK1BA_HUMAN Increases Expression [140]
Aldo-keto reductase family 1 member B1 (AKR1B1) OTRX72TH ALDR_HUMAN Increases Expression [140]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Increases Expression [140]
Aldo-keto reductase family 1 member C3 (AKR1C3) OTU2SXBA AK1C3_HUMAN Increases Expression [140]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Affects Expression [140]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Increases Expression [140]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Increases Expression [140]
Toll-like receptor 4 (TLR4) OTP7ML3S TLR4_HUMAN Increases Expression [141]
Tumor necrosis factor receptor superfamily member 10A (TNFRSF10A) OTBPCU2O TR10A_HUMAN Decreases Expression [142]
NF-kappa-B inhibitor epsilon (NFKBIE) OTLAYEL9 IKBE_HUMAN Increases Stability [143]
Myc box-dependent-interacting protein 1 (BIN1) OTK8O0X8 BIN1_HUMAN Increases Expression [131]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [144]
Inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) OT9RDS3H IKKB_HUMAN Decreases Expression [129]
Inhibitor of nuclear factor kappa-B kinase subunit alpha (CHUK) OTLF4ZB1 IKKA_HUMAN Increases Expression [129]
Apoptosis regulatory protein Siva (SIVA1) OTDT0XZK SIVA_HUMAN Decreases Expression [131]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [145]
High affinity copper uptake protein 1 (SLC31A1) OTXLRTUB COPT1_HUMAN Decreases Degradation [146]
CASP8 and FADD-like apoptosis regulator (CFLAR) OTX14BAS CFLAR_HUMAN Decreases Expression [131]
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1) OTDTF5BU SUV91_HUMAN Decreases Expression [131]
Serine protease HTRA2, mitochondrial (HTRA2) OTC7616F HTRA2_HUMAN Affects Localization [147]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Increases Activity [148]
Nuclear protein 1 (NUPR1) OT4FU8C0 NUPR1_HUMAN Increases Expression [149]
Toll-like receptor 2 (TLR2) OTGO5P4R TLR2_HUMAN Increases Expression [129]
DENN domain-containing protein 4B (DENND4B) OTFEO8KG DEN4B_HUMAN Increases Expression [150]
Growth arrest and DNA damage-inducible protein GADD45 beta (GADD45B) OTL9I7LO GA45B_HUMAN Increases Expression [150]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) OTYG179K PR15A_HUMAN Increases Expression [150]
Natural cytotoxicity triggering receptor 1 (NCR1) OT6MZKQY NCTR1_HUMAN Decreases Expression [151]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) OT8V1J4M GA45G_HUMAN Increases Expression [145]
BAG family molecular chaperone regulator 3 (BAG3) OTVXYUDQ BAG3_HUMAN Increases Expression [150]
Apoptosis-inducing factor 1, mitochondrial (AIFM1) OTKPWB7Q AIFM1_HUMAN Affects Localization [147]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [152]
Insulin-like growth factor II (IGF2) OTJ4O6MW IGF2_HUMAN Decreases Response To Substance [153]
Prelamin-A/C (LMNA) OT3SG7ZR LMNA_HUMAN Increases Cleavage [154]
RAF proto-oncogene serine/threonine-protein kinase (RAF1) OT51LSFO RAF1_HUMAN Decreases Expression [155]
Receptor tyrosine-protein kinase erbB-2 (ERBB2) OTOAUNCK ERBB2_HUMAN Decreases Phosphorylation [156]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Increases Activity [157]
Galectin-2 (LGALS2) OTY08TMQ LEG2_HUMAN Decreases Expression [131]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Increases Phosphorylation [158]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Decreases Expression [159]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Decreases Expression [129]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Decreases Expression [129]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Decreases Activity [127]
Integrin alpha-V (ITGAV) OTAM7JTR ITAV_HUMAN Increases Expression [129]
Cathepsin B (CTSB) OTP9G5QB CATB_HUMAN Increases Localization [148]
Heat shock protein HSP 90-alpha (HSP90AA1) OTLG1WPK HS90A_HUMAN Decreases Expression [129]
Heat shock protein HSP 90-beta (HSP90AB1) OTR69EG7 HS90B_HUMAN Increases Expression [141]
Growth-regulated alpha protein (CXCL1) OT3WCTZV GROA_HUMAN Increases Expression [150]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [150]
Poly polymerase 1 (PARP1) OT310QSG PARP1_HUMAN Increases Cleavage [160]
Heat shock 70 kDa protein 1A (HSPA1A) OTKGIE76 HS71A_HUMAN Increases Expression [141]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [150]
C-C motif chemokine 3 (CCL3) OTW2H3ND CCL3_HUMAN Decreases Expression [161]
Cytochrome c oxidase subunit 8A, mitochondrial (COX8A) OTU0NR39 COX8A_HUMAN Decreases Expression [157]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [162]
Osteopontin (SPP1) OTJGC23Y OSTP_HUMAN Decreases Expression [129]
Growth hormone receptor (GHR) OT8WUWMU GHR_HUMAN Increases Expression [141]
Parathyroid hormone-related protein (PTHLH) OTI1JF13 PTHR_HUMAN Decreases Expression [161]
Interferon-induced transmembrane protein 1 (IFITM1) OTECO1G8 IFM1_HUMAN Decreases Expression [131]
Protein Cripto (CRIPTO) OT46DZXJ TDGF1_HUMAN Increases Expression [141]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Decreases Expression [129]
Tissue factor (F3) OT3MSU3B TF_HUMAN Increases Expression [163]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Increases Expression [164]
Interleukin-1 receptor type 1 (IL1R1) OTTU8959 IL1R1_HUMAN Increases Expression [141]
Transcription factor 4 (TCF4) OTB9ASTK ITF2_HUMAN Increases Expression [141]
Histone H2AX (H2AX) OT18UX57 H2AX_HUMAN Decreases Phosphorylation [165]
Interleukin-7 receptor subunit alpha (IL7R) OTBMFLQQ IL7RA_HUMAN Increases Expression [129]
Heat shock 70 kDa protein 6 (HSPA6) OTH4S7WB HSP76_HUMAN Increases Expression [150]
Transcription factor JunB (JUNB) OTG2JXV5 JUNB_HUMAN Decreases Expression [166]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Decreases Expression [129]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Increases Expression [129]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [145]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Increases Expression [150]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Decreases Expression [167]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Affects Expression [142]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Decreases Activity [127]
Tumor necrosis factor receptor superfamily member 6 (FAS) OTP9XG86 TNR6_HUMAN Decreases Expression [129]
DnaJ homolog subfamily B member 1 (DNAJB1) OTCOSEVH DNJB1_HUMAN Increases Expression [150]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Increases Expression [141]
Pentraxin-related protein PTX3 (PTX3) OTPXHRKU PTX3_HUMAN Decreases Expression [129]
CD27 antigen (CD27) OTH7NA58 CD27_HUMAN Increases Expression [141]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Activity [155]
Calreticulin (CALR) OTYD2TR1 CALR_HUMAN Increases Expression [139]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Activity [155]
Tyrosine-protein phosphatase non-receptor type 6 (PTPN6) OT33XNZM PTN6_HUMAN Decreases Expression [131]
SHC-transforming protein 1 (SHC1) OT1J5IRN SHC1_HUMAN Decreases Expression [129]
Nitric oxide synthase 1 (NOS1) OT7M8XVG NOS1_HUMAN Increases Expression [139]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Activity [155]
DNA replication licensing factor MCM7 (MCM7) OT6FXC6K MCM7_HUMAN Decreases Expression [131]
Catenin beta-1 (CTNNB1) OTZ932A3 CTNB1_HUMAN Increases Expression [168]
Replication protein A 14 kDa subunit (RPA3) OT8JAQGL RFA3_HUMAN Decreases Expression [131]
Pro-adrenomedullin (ADM) OT7T0TA4 ADML_HUMAN Decreases Expression [129]
Insulin receptor substrate 1 (IRS1) OTNO82CU IRS1_HUMAN Decreases Degradation [169]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [131]
Alpha-synuclein (SNCA) OTPWC1MR SYUA_HUMAN Increases Expression [141]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Decreases Expression [170]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [145]
Small ribosomal subunit protein eS19 (RPS19) OTBKGP48 RS19_HUMAN Increases Expression [150]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Activity [158]
Caspase-2 (CASP2) OTUDYSPP CASP2_HUMAN Increases Cleavage [150]
Mitogen-activated protein kinase 8 (MAPK8) OTEREYS5 MK08_HUMAN Increases Phosphorylation [171]
Mitogen-activated protein kinase 9 (MAPK9) OTCEVJ9E MK09_HUMAN Increases Phosphorylation [171]
Proliferation marker protein Ki-67 (MKI67) OTA8N1QI KI67_HUMAN Decreases Expression [172]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [127]
Tumor necrosis factor ligand superfamily member 6 (FASLG) OTZARCHH TNFL6_HUMAN Increases Expression [173]
Caspase-4 (CASP4) OTVQTV1L CASP4_HUMAN Increases Activity [158]
Isocitrate dehydrogenase subunit alpha, mitochondrial (IDH3A) OT5QQB5L IDH3A_HUMAN Decreases Expression [157]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Decreases Expression [174]
Small ribosomal subunit protein mS29 (DAP3) OTNPEZYM RT29_HUMAN Increases Expression [131]
Breast cancer type 2 susceptibility protein (BRCA2) OTF1XSV1 BRCA2_HUMAN Decreases Expression [170]
Interleukin-1 receptor-associated kinase 1 (IRAK1) OT133G8J IRAK1_HUMAN Decreases Expression [129]
DNA mismatch repair protein Msh6 (MSH6) OT46FP09 MSH6_HUMAN Decreases Expression [131]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Activity [175]
Caspase-6 (CASP6) OTXLD3EC CASP6_HUMAN Increases Cleavage [160]
Hepatocyte nuclear factor 3-alpha (FOXA1) OTEBY0TD FOXA1_HUMAN Decreases Expression [129]
BH3-interacting domain death agonist (BID) OTOSHSHU BID_HUMAN Increases Cleavage [145]
Histone deacetylase 4 (HDAC4) OTQNGD32 HDAC4_HUMAN Decreases Expression [131]
NACHT, LRR and PYD domains-containing protein 12 (NLRP12) OTGR132Z NAL12_HUMAN Increases Expression [129]
Beta-2-microglobulin (B2M) OTDWN6NX B2MG_HUMAN Decreases Expression [176]
C-C motif chemokine 8 (CCL8) OTCTWYN8 CCL8_HUMAN Affects Expression [142]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Affects Localization [147]
Heat shock factor protein 1 (HSF1) OTYNJ4KP HSF1_HUMAN Increases Expression [141]
Nuclear factor NF-kappa-B p100 subunit (NFKB2) OTS231V7 NFKB2_HUMAN Decreases Expression [167]
E3 ubiquitin-protein ligase Mdm2 (MDM2) OTOVXARF MDM2_HUMAN Increases Cleavage [177]
Dystonin (DST) OTHZBM4X DYST_HUMAN Increases Expression [131]
Heat shock factor protein 2 (HSF2) OTXNJIJ9 HSF2_HUMAN Increases Expression [178]
DNA repair protein RAD51 homolog 1 (RAD51) OTNVWGC1 RAD51_HUMAN Decreases Expression [170]
Fragile X messenger ribonucleoprotein 1 (FMR1) OTWEV0T5 FMR1_HUMAN Decreases Expression [131]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [179]
Bcl-2-like protein 1 (BCL2L1) OTRC5K9O B2CL1_HUMAN Decreases Expression [148]
Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1) OT2YYI1A MCL1_HUMAN Increases Cleavage [160]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3) OT4SO7J4 BNIP3_HUMAN Increases Expression [154]
Baculoviral IAP repeat-containing protein 1 (NAIP) OTLA925F BIRC1_HUMAN Affects Expression [167]
Chromatin assembly factor 1 subunit A (CHAF1A) OTXSSY4H CAF1A_HUMAN Decreases Expression [131]
S-phase kinase-associated protein 2 (SKP2) OTD5B41X SKP2_HUMAN Decreases Expression [180]
Serine-protein kinase ATM (ATM) OTQVOHLT ATM_HUMAN Increases Cleavage [177]
Bcl-2-interacting killer (BIK) OTTH1T3D BIK_HUMAN Increases Activity [148]
Interleukin-18 receptor 1 (IL18R1) OT83XMPQ IL18R_HUMAN Increases Expression [141]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Increases Expression [181]
Baculoviral IAP repeat-containing protein 2 (BIRC2) OTFXFREP BIRC2_HUMAN Decreases Expression [143]
Receptor-interacting serine/threonine-protein kinase 1 (RIPK1) OTC41R1E RIPK1_HUMAN Decreases Expression [129]
Cullin-1 (CUL1) OTXPE1UZ CUL1_HUMAN Increases Expression [141]
Cullin-3 (CUL3) OTDNOAPM CUL3_HUMAN Decreases Expression [131]
Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1) OTXEE550 APR_HUMAN Decreases Expression [167]
Caspase-8 (CASP8) OTA8TVI8 CASP8_HUMAN Increases Cleavage [177]
Transcription elongation factor A protein-like 1 (TCEAL1) OTAPG2L5 TCAL1_HUMAN Increases Expression [141]
Interferon regulatory factor 4 (IRF4) OT1DHQ1P IRF4_HUMAN Decreases Expression [166]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Increases Activity [157]
Hsp90 co-chaperone Cdc37 (CDC37) OTYDT4A7 CDC37_HUMAN Increases Expression [141]
Bcl-2 homologous antagonist/killer (BAK1) OTDP6ILW BAK_HUMAN Increases Expression [182]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Increases Expression [183]
Carbonic anhydrase 9 (CA9) OTNA51XT CAH9_HUMAN Decreases Expression [183]
TIR domain-containing adapter molecule 2 (TICAM2) OTK7GIJ5 TCAM2_HUMAN Increases Expression [129]
Cell division cycle and apoptosis regulator protein 1 (CCAR1) OTUXLQZZ CCAR1_HUMAN Increases Expression [184]
Ectodysplasin-A receptor-associated adapter protein (EDARADD) OT0G52MC EDAD_HUMAN Increases Expression [141]
DNA-binding death effector domain-containing protein 2 (DEDD2) OT0WXRWT DEDD2_HUMAN Increases Expression [131]
Heat shock protein 105 kDa (HSPH1) OTVRR73T HS105_HUMAN Increases Expression [145]
CREB-binding protein (CREBBP) OTPA4QGM CBP_HUMAN Decreases Expression [167]
Histone acetyltransferase KAT2B (KAT2B) OTWQITWK KAT2B_HUMAN Decreases Expression [129]
Bcl-2-like protein 2 (BCL2L2) OTMKVO0J B2CL2_HUMAN Increases Expression [185]
N-alpha-acetyltransferase 80 (NAA80) OTLWR71Z NAA80_HUMAN Decreases Expression [131]
MOB kinase activator 3A (MOB3A) OTILIOXF MOB3A_HUMAN Decreases Expression [131]
Baculoviral IAP repeat-containing protein 7 (BIRC7) OTITCGHB BIRC7_HUMAN Decreases Expression [186]
NACHT, LRR and PYD domains-containing protein 3 (NLRP3) OTZM6MHU NLRP3_HUMAN Decreases Expression [131]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [187]
Tribbles homolog 3 (TRIB3) OTG5OS7X TRIB3_HUMAN Increases Expression [139]
Cell growth regulator with EF hand domain protein 1 (CGREF1) OTBZQX97 CGRE1_HUMAN Increases Expression [141]
Myeloid differentiation primary response protein MyD88 (MYD88) OTB4D6FL MYD88_HUMAN Decreases Expression [129]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) OTJGE772 CHAC1_HUMAN Increases Expression [150]
Fanconi anemia group D2 protein (FANCD2) OTVEB5LF FACD2_HUMAN Decreases Expression [188]
Eukaryotic translation initiation factor 2A (EIF2A) OTWXELQP EIF2A_HUMAN Decreases Phosphorylation [189]
DNA replication factor Cdt1 (CDT1) OTVY53VG CDT1_HUMAN Decreases Expression [131]
Interleukin-23 subunit alpha (IL23A) OTYO99HC IL23A_HUMAN Increases Expression [141]
Transcription factor 7-like 2 (TCF7L2) OTVWPZ8B TF7L2_HUMAN Increases Expression [141]
Diablo IAP-binding mitochondrial protein (DIABLO) OTHJ9MCZ DBLOH_HUMAN Increases Expression [167]
Sphingosine kinase 1 (SPHK1) OTWYPBVD SPHK1_HUMAN Decreases Expression [190]
Anaphase-promoting complex subunit 11 (ANAPC11) OTK2SJXR APC11_HUMAN Decreases Expression [131]
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) OT0DZGY4 E2AK3_HUMAN Increases Phosphorylation [150]
Lipid transferase CIDEB (CIDEB) OT873IYM CIDEB_HUMAN Decreases Expression [131]
Adenine DNA glycosylase (MUTYH) OTXTKI7Q MUTYH_HUMAN Decreases Expression [131]
Cell cycle progression protein 1 (CCPG1) OT0IHDKL CCPG1_HUMAN Increases Expression [129]
FAS-associated factor 1 (FAF1) OTGAMLM4 FAF1_HUMAN Increases Expression [141]
Transcription factor 19 (TCF19) OT7NKLF9 TCF19_HUMAN Decreases Expression [131]
Cyclic AMP-dependent transcription factor ATF-5 (ATF5) OT03QCLM ATF5_HUMAN Increases Expression [145]
Rho-related BTB domain-containing protein 2 (RHOBTB2) OT2DATFX RHBT2_HUMAN Increases Response To Substance [191]
Beclin-1 (BECN1) OT4X293M BECN1_HUMAN Decreases Response To Substance [192]
Palmitoyl thioesterase CPT1C (CPT1C) OT8F1MBF CPT1C_HUMAN Increases Response To Substance [191]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 (ATP2A1) OT959A3A AT2A1_HUMAN Affects Response To Substance [193]
Histone deacetylase 6 (HDAC6) OT9W9MXQ HDAC6_HUMAN Decreases Response To Substance [194]
Serine/threonine-protein kinase 4 (STK4) OTBRYNNH STK4_HUMAN Increases Response To Substance [195]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Response To Substance [191]
Transcription factor SOX-8 (SOX8) OTEJXYZM SOX8_HUMAN Increases Response To Substance [191]
DNA repair endonuclease XPF (ERCC4) OTFIOPG1 XPF_HUMAN Increases Response To Substance [191]
Polyunsaturated fatty acid lipoxygenase ALOX12 (ALOX12) OTFL5KR5 LOX12_HUMAN Increases Response To Substance [191]
Heat shock protein beta-1 (HSPB1) OTHFZ8ED HSPB1_HUMAN Decreases Response To Substance [196]
Peroxisome proliferator-activated receptor delta (PPARD) OTI4WTOP PPARD_HUMAN Increases Response To Substance [191]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Increases Response To Substance [191]
Unconventional myosin-Va (MYO5A) OTMWLP3E MYO5A_HUMAN Increases Response To Substance [191]
Proteasome subunit beta type-5 (PSMB5) OTOZXAS6 PSB5_HUMAN Decreases Response To Substance [197]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Increases Response To Substance [198]
Mannose-binding protein C (MBL2) OTS63HG5 MBL2_HUMAN Increases Response To Substance [191]
Nucleophosmin (NPM1) OTTBYYT0 NPM_HUMAN Increases Response To Substance [199]
BRCA1-associated RING domain protein 1 (BARD1) OTTC0Z9Y BARD1_HUMAN Increases Response To Substance [198]
General transcription and DNA repair factor IIH helicase subunit XPB (ERCC3) OTVAW3P1 ERCC3_HUMAN Increases Response To Substance [191]
Insulin-like growth factor 1 receptor (IGF1R) OTXJIF13 IGF1R_HUMAN Increases Response To Substance [191]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1) OTY9R6FZ ERN1_HUMAN Decreases Response To Substance [158]
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⏷ Show the Full List of 686 DOT(s)

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106 Mitotic checkpoint genes, hsMAD2 and BubR1, in oesophageal squamous cancer cells and their association with 5-fluorouracil and cisplatin-based radiochemotherapy. Clin Oncol (R Coll Radiol). 2008 Oct;20(8):639-46. doi: 10.1016/j.clon.2008.06.010. Epub 2008 Aug 8.
107 Involvement of high mobility group box 1 in the development and maintenance of chemotherapy-induced peripheral neuropathy in rats. Toxicology. 2016 Jul 15;365:48-58. doi: 10.1016/j.tox.2016.07.016. Epub 2016 Jul 27.
108 CCL2 expression in primary ovarian carcinoma is correlated with chemotherapy response and survival outcomes. Anticancer Res. 2010 Dec;30(12):4791-8.
109 CD133+ cancer stem cell-like cells derived from uterine carcinosarcoma (malignant mixed Mllerian tumor). Stem Cells. 2011 Oct;29(10):1485-95. doi: 10.1002/stem.711.
110 ATF3 inhibits arsenic-induced malignant transformation of human bronchial epithelial cells by attenuating inflammation. Toxicology. 2021 Aug;460:152890. doi: 10.1016/j.tox.2021.152890. Epub 2021 Aug 6.
111 Therapeutic interactions between stathmin inhibition and chemotherapeutic agents in prostate cancer. Mol Cancer Ther. 2006 Dec;5(12):3248-57. doi: 10.1158/1535-7163.MCT-06-0227.
112 MIAT shuttled by tumor-secreted exosomes promotes paclitaxel resistance in esophageal cancer cells by activating the TAF1/SREBF1 axis. J Biochem Mol Toxicol. 2023 Aug;37(8):e23380. doi: 10.1002/jbt.23380. Epub 2023 May 3.
113 Reduced expression of Rho guanine nucleotide dissociation inhibitor-alpha modulates the cytotoxic effect of busulfan in HEK293 cells. Anticancer Drugs. 2007 Mar;18(3):333-40. doi: 10.1097/CAD.0b013e328011fd7f.
114 Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy. Biochem Pharmacol. 2011 Nov 15;82(10):1384-90. doi: 10.1016/j.bcp.2011.06.007. Epub 2011 Jun 13.
115 Inhibition of the notch signaling pathway overcomes resistance of cervical cancer cells to paclitaxel through retardation of the epithelial-mesenchymal transition process. Environ Toxicol. 2021 Sep;36(9):1758-1764. doi: 10.1002/tox.23296. Epub 2021 May 28.
116 Discovery of N-hydroxyindole-based inhibitors of human lactate dehydrogenase isoform A (LDH-A) as starvation agents against cancer cells. J Med Chem. 2011 Mar 24;54(6):1599-612. doi: 10.1021/jm101007q. Epub 2011 Feb 18.
117 Pculin02H, a curcumin derivative, inhibits proliferation and clinical drug resistance of HER2-overexpressing cancer cells. Chem Biol Interact. 2015 Jun 25;235:17-26. doi: 10.1016/j.cbi.2015.04.005. Epub 2015 Apr 10.
118 Antisense therapy targeting MDM2 oncogene in prostate cancer: Effects on proliferation, apoptosis, multiple gene expression, and chemotherapy. Proc Natl Acad Sci U S A. 2003 Sep 30;100(20):11636-41. doi: 10.1073/pnas.1934692100. Epub 2003 Sep 16.
119 Clusterin regulates drug-resistance in melanoma cells. J Invest Dermatol. 2005 Jun;124(6):1300-7. doi: 10.1111/j.0022-202X.2005.23720.x.
120 Epigenetic inactivation of the CHFR gene in cervical cancer contributes to sensitivity to taxanes. Int J Oncol. 2007 Oct;31(4):713-20.
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