General Information of Drug (ID: DM8VCBE)

Drug Name
Ibuprofen Drug Info
Synonyms
ibuprofen; 15687-27-1; 2-(4-Isobutylphenyl)propanoic acid; Motrin; Brufen; Advil; Nurofen; Dolgit; Nuprin; Liptan; Ibuprocin; Buburone; Medipren; Butylenin; Ibumetin; Anflagen; Lamidon; Ebufac; Mynosedin; Trendar; Roidenin; Apsifen; Haltran; Epobron; Nobgen; Adran; Nobfen; Rufen; PediaProfen; Andran; Bluton; Nobfelon; Pantrop; Brufort; Suspren; Rebugen; Tabalon; Inabrin; (RS)-Ibuprofen; Urem; Anco; 2-[4-(2-methylpropyl)phenyl]propanoic acid; Ibu-slo; Napacetin; Brufanic; Ibuprohm; Ibufen; Ibren; 4-Isobutylhydratropic acid; p-Isobutylhydratropic acid; Actiprofen; Alaxan; Algofen; Amelior; Amersol; Amibufen; Anafen; Antagil; Antalfene; Antarene; Antiflam; Artofen; Artril; Balkaprofen; Betaprofen; Bloom; Brofen; Bruflam; Bufeno; Bufigen; Bukrefen; Bupron; Buracaps; Burana; Carol;Cesra; Citalgan; Cobo; Codral; Combiflam; Cunil; Daiprophen; Dalsy; Dansida; Dentigoa; Dibufen; Dignoflex; Dolgirid; Dolibu; Dolmaral; Dolocyl; Dolofen; Dolofin; Dolofort; Dologel; Dolomax; Doloren; Dolormin; Doltibil; Dolven; Dorival; Drin; Duafen; Duobrus; Dysdolen; Easifon; Emflam; Eputex; Ergix; Esprenit; Exneural; Faspic; Femadon; Femafen; Femapirin; Femidol; Fenbid;Fendol; Fenspan; Fibraflex; Gelufene; Gofen; Grefen; Gynofug; Ibol; Ibu; Ibubest; Ibubeta; Ibucasen; Ibudol; Ibudolor; Ibuflamar; Ibufug; Ibugel; Ibugen; Ibugesic; Ibuhexal; Ibulagic; Ibular; Ibulav; Ibuleve; Ibulgan; Ibumed; Ibumerck; Ibupirac; Ibuprin; Ibuprofene; Ibuprofeno; Ibuprofenum; Ibuprophen; Ibusal; Ibutid; Ifen; Inflam; Inoven; Ipren; Irfen; Isodol; Jenaprofen; Junifen; Kesan; Kratalgin; Lebrufen; Librofem; Lidifen; Lopane; Malafene; Manypren; Melfen; Mensoton; Midol; Moment; Narfen; Neobrufen; Nerofen; Noalgil; Nobafon; Noritis; Norton; Novadol; Novogent; Novoprofen; Nuprilan; Optifen; Opturem; Oralfene; Ostarin; Ostofen; Ozonol; Paduden; Panafen; Paxofen; Perofen; Proartinal; Profen; Proflex; Provon; Quadrax; Rafen; Ranofen; Relcofen; Rhinadvil; Rofen; Rufin; Rupan; Sadefen; Salivia; Salprofen; Seclodin; Sednafen; Seklodin; Seskafen; Siyafen; Solpaflex; Solufen; Stelar; Sugafen; Suprafen; Syntofene; Tatanal; Tempil; Tofen; Tonal; Unipron; Upfen; Uprofen; Zafen; Zofen; DOLO PUREN; Deep Relief; Donjust B; Motrin IB; Novogent N; Togal N; Adex 200; Artril 300; Brufen 400; I 4883; IP 82; IP82; Midol 200; RD 13621; Tabalon 400; U 18573; UCB 79171; VUFB 9649; Act-3; Advil (TN); Ak+C2278tren; Aktre (TN); Alaxan (TN); Algoflex (TN); Alivium (TN); Am-Fam 400; Apsifen-F; Arthrofen (TN); Bonifen (TN); Brufen (TN); Bugesic (TN); Burana (TN); Caldolor (TN); Calprofen (TN); Cap-Profen; Dalsy (TN); Dismenol (TN); Diverin (TN); Dolgit (TN); Dolo-Dolgit; Dolofen-F; Dolofort (TN); Doloraz (TN); Dolormin (TN); Dorival (TN); Dura-Ibu; Ebufac (TN); Emflam-200; EmuProfen (TN); Espidifen (TN); Eve (TN); Fenbid (TN); Fenpaed (TN); Finalflex (TN); Galprofen (TN); Hedex (TN); Herron Blue (TN); IB-100; IBUFEN (TN); IP-82; Ibalgin (TN); Ibu-Attritin; Ibu-Tab; Ibu-Tab 200; Ibu-slow; IbuHEXAL (TN); Ibugel (TN); Ibuleve (TN); Ibum (TN); Ibumax (TN); Ibumetin (TN); Ibuprom (TN); Ibuprosyn (TN); Ibux (TN); Ibuxin (TN); Ipren (TN); Kratalgin (TN); Medicol (TN); Moment (TN); Motrin (TN); Nagifen-D; Narfen (TN); Neo-Helvagit; Neo-Mindol; Neobrufen (TN); Neofen (TN); Norvectan (TN); Novo-Profen; Nuprin (TN); Nureflex (TN); Nurofen (TN); Orbifen (TN); Panafen (TN); Pedia-Profen; Perifar (TN); Profin (TN); Ratiodolor (TN); Retard (TN); Rimafen (TN); Salvarina (TN); Solpaflex (TN); Spedifen (TN); Speedpain NANO (TN); Spidifen (TN); Tab-Profen; U-18573; Upfen (TN); ACHES-N-PAIN; Act-3 (TN); Dolo-Spedifen (TN); I-profen (TN); IBU-Ratiopharm (TN); Ibu-Vivimed (TN); U-18,573; IBUPROPHEN
Indication
Disease Entry ICD 11 Status REF
Dysmenorrhea GA34.3 Approved [1]
Fever MG26 Approved [1]
Headache 8A80-8A84 Approved [1]
Osteoarthritis FA00-FA05 Approved [1]
Pain MG30-MG3Z Approved [2]
Patent ductus arteriosus Approved [1]
Therapeutic Class
Analgesics
Cross-matching ID
PubChem CID
3672
ChEBI ID
CHEBI:5855
CAS Number
CAS 15687-27-1
TTD Drug ID
DM8VCBE
VARIDT Drug ID
DR00663
INTEDE Drug ID
DR0844
ACDINA Drug ID
D00320

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DTP
DME
DOT
Drug Status:
Clinical Trial Drug(s)
Discontinued Drug(s)
Investigative Drug(s)
Approved Drug(s)
Patented Agent(s)
Preclinical Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Reparixin DMVBA7I Pancreatic islet transplantation failure NE84 Phase 3 [3]
SCH-527123 DMPUAOE Chronic obstructive pulmonary disease CA22 Phase 2 [18]
SX-682 DMHMG6X Melanoma 2C30 Phase 1 [19]
INDOPROFEN DM5QSKN Gout FA25 Withdrawn from market [3]
R-ketoprofen DMHSUQ1 N. A. N. A. Discontinued in Phase 2 [3]
2-(3-Isopropyl-phenyl)-propionic acid DMUOWNE Discovery agent N.A. Investigative [3]
2-[3-(1-Phenyl-ethyl)-phenyl]-propionic acid DMWIUR0 Discovery agent N.A. Investigative [3]
(R)-2-(4-Isobutyl-phenyl)-propionamide DMBQ0PR Discovery agent N.A. Investigative [3]
(R)-N-Hydroxy-2-(4-isobutyl-phenyl)-propionamide DMWRIQG Discovery agent N.A. Investigative [3]
2-[3-(2-Methyl-butyl)-phenyl]-propionic acid DMKSDT4 Discovery agent N.A. Investigative [3]
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Drug(s) Targeting Interleukin-8 (IL8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
ABX-IL8 DMCZFMS Melanoma 2C30 Phase 2 [20]
BMS-986253 DM42B0C Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2 [21]
MDX-018 DML5FX2 Autoimmune diabetes 5A10 Phase 1 [22]
R-ketoprofen DMHSUQ1 N. A. N. A. Discontinued in Phase 2 [4]
2-(2-(2,5-dichlorophenylamino)phenyl)acetic acid DM54M6C Discovery agent N.A. Investigative [4]
2-(2-(2-chlorophenylamino)phenyl)acetic acid DMPLV3A Discovery agent N.A. Investigative [4]
2-(2-(2-fluorophenylamino)phenyl)acetic acid DMVQ68F Discovery agent N.A. Investigative [4]
2-(2-(2-chlorophenoxy)phenyl)acetic acid DMBP1TQ Discovery agent N.A. Investigative [4]
2-(2-(2-fluorophenoxy)phenyl)acetic acid DMDSUR2 Discovery agent N.A. Investigative [4]
⏷ Show the Full List of 9 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clotrimazole DMMFCIH Cutaneous candidiasis 1F23.14 Approved [23]
Reparixin DMVBA7I Pancreatic islet transplantation failure NE84 Phase 3 [3]
SCH-527123 DMPUAOE Chronic obstructive pulmonary disease CA22 Phase 2 [24]
SB-265610 DM8TKG5 Asthma CA23 Phase 2 [25]
AZD-5069 DM3JSFK Asthma CA23 Phase 2 [26]
PS-938285 DMHZIFJ Chronic obstructive pulmonary disease CA22 Phase 2 [27]
GSK1325756 DMA6RBF Chronic obstructive pulmonary disease CA22 Phase 2 [28]
SB-656933 DMCY785 Chronic obstructive pulmonary disease CA22 Phase 2 [29]
RIST4721 DMA3DKO Hidradenitis suppurativa ED92.0 Phase 2 [30]
SX-682 DMHMG6X Melanoma 2C30 Phase 1 [19]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Naproxen DMZ5RGV Bursitis Approved [31]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [32]
Indomethacin DMSC4A7 Bursitis Approved [33]
Celecoxib DM6LOQU Dysmenorrhea GA34.3 Approved [34]
Nabumetone DMAT2XH Osteoarthritis FA00-FA05 Approved [35]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [36]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [37]
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [38]
Aminosalicylic Acid DMENSL5 Crohn disease DD70 Approved [33]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [39]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [7]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [7]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [40]
Quercetin DM3NC4M Obesity 5B81 Approved [7]
Propicillin DMWDHUZ Bacterial infection 1A00-1C4Z Approved [7]
Milchsaure DM462BT Pruritus EC90 Investigative [41]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [6]
Phosphate DMUXQG7 Constipation DD91.1 Approved [6]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [6]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [6]
Drug(s) Metabolized By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [42]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [43]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [44]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [45]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [46]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [47]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [48]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [49]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [43]
Verapamil DMA7PEW Angina pectoris BA40 Approved [11]
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Drug(s) Metabolized By Cytochrome P450 2C8 (CYP2C8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [50]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [51]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [51]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [9]
Verapamil DMA7PEW Angina pectoris BA40 Approved [52]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [53]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [54]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [51]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [55]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Metabolized By Cytochrome P450 2C9 (CYP2C9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [57]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [58]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [59]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [9]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [60]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [9]
Verapamil DMA7PEW Angina pectoris BA40 Approved [61]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [62]
Estrone DM5T6US Acne vulgaris ED80 Approved [63]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
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Drug(s) Metabolized By Mephenytoin 4-hydroxylase (CYP2C19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amoxicillin DMUYNEI Acute otitis media AB00 Approved [65]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [57]
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [66]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [67]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [9]
Verapamil DMA7PEW Angina pectoris BA40 Approved [68]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [69]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [64]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [70]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [56]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tamoxifen DMLB0EZ Breast cancer 2C60-2C65 Approved [71]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [72]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [73]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [55]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [74]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [75]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [76]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [77]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [11]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [79]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [80]
Cerivastatin DMXCM7H Hyperlipidaemia 5C80 Approved [81]
PITAVASTATIN CALCIUM DM1UJO0 Dyslipidemia 5C80-5C81 Approved [74]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [75]
Ezetimibe DM7A8TW Atherosclerosis BD40 Approved [82]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [77]
Losartan DM72JXH Diabetic kidney disease GB61.Z Approved [11]
Naproxen DMZ5RGV Bursitis Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [84]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [78]
Sorafenib DMS8IFC Adenocarcinoma 2D40 Approved [85]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [11]
Mycophenolate mofetil DMPQAGE Hepatosplenic T-cell lymphoma Approved [86]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [11]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [87]
Nateglinide DMLK2QH Diabetic complication 5A2Y Approved [11]
Haloperidol DM96SE0 Delirium Approved [11]
Naproxen DMZ5RGV Bursitis Approved [83]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexibuprofen DMFYBD0 Ankylosing spondylitis FA92.0 Approved [88]
Drug(s) Affected By Myeloperoxidase (MPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dapsone DM4LT8A Acne vulgaris ED80 Approved [89]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [89]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [91]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [92]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [93]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [94]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [95]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [96]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [97]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Phenoxybenzamine DM8KSQH Malignant essential hypertension BA00 Approved [98]
Quinine DMSWYF5 Malaria 1F40-1F45 Approved [99]
Trospium chloride DM32XZT Discovery agent N.A. Approved [100]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [101]
Lamivudine DMI347A Chronic HBV infection 1E51.0Z Approved [102]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [103]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [108]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [103]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [109]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [103]
Succinic acid DMDWICP Malnutrition 5B50-5B71 Approved [110]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [103]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [111]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [103]
Ketoprofen DMRKXPT Bursitis Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [103]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [103]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [114]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [104]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [103]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [103]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [103]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [116]
Mefenamic acid DMK7HFI Dysmenorrhea GA34.3 Approved [103]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [117]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [103]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [118]
Ketoprofen DMRKXPT Bursitis Approved [103]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [103]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Paclitaxel DMLB81S Breast carcinoma Approved [120]
Allopurinol DMLPAOB Gout FA25 Approved [120]
Bumetanide DMRV7H0 Congestive heart failure BD10 Approved [120]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [120]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [120]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [120]
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [121]
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Drug(s) Affected By Aromatase (CYP19A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [122]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [123]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [124]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [124]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
FADROZOLE DM3C5GZ Breast cancer 2C60-2C65 Approved [127]
Bifonazole DM3KN7V Fungal infection 1F29-1F2F Approved [128]
Quercetin DM3NC4M Obesity 5B81 Approved [129]
Fluoxetine DM3PD2C Bipolar depression Approved [124]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [130]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [132]
Quercetin DM3NC4M Obesity 5B81 Approved [133]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [134]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [135]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Bupivacaine DM4PRFC Anaesthesia 9A78.6 Approved [137]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
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Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Selenium DM25CGV N. A. N. A. Approved [140]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [141]
Methotrexate DM2TEOL Anterior urethra cancer Approved [142]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [144]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [146]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Fedratinib DM4ZBK6 Myelofibrosis 2A20.2 Approved [147]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [147]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [148]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Selenium DM25CGV N. A. N. A. Approved [140]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Folic Acid DMEMBJC Colorectal carcinoma Approved [152]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Arsenic DMTL2Y1 N. A. N. A. Approved [153]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [155]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [155]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
Milchsaure DM462BT Pruritus EC90 Investigative [157]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [158]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Annexin A9 (ANXA9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [162]
Urethane DM7NSI0 N. A. N. A. Phase 4 [163]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [138]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [164]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [165]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [167]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [139]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [169]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [171]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [142]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [172]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [173]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Folic Acid DMEMBJC Colorectal carcinoma Approved [176]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [177]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [178]
PD-0325901 DM27D4J Breast cancer 2C60-2C65 Phase 2 [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Complement C3 (C3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [182]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [183]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-1 alpha (IL1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [185]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [185]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [187]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [185]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [134]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A1 (ANXA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [188]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [190]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Selenium DM25CGV N. A. N. A. Approved [193]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [195]
Epinephrine DM3KJBC Acute asthma CA23 Approved [196]
Quercetin DM3NC4M Obesity 5B81 Approved [197]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [199]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [194]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [201]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [202]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [203]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [204]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [205]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [206]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peptide YY (PYY)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [207]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [207]
Orlistat DMRJSP8 Obesity 5B81 Approved [208]
Arsenic DMTL2Y1 N. A. N. A. Approved [209]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [138]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Clusterin (CLU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [210]
Selenium DM25CGV N. A. N. A. Approved [140]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [210]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Levamisole DM5EN79 Parasitic infection 1D0Y-1G2Z Approved [212]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
Methazolamide DM7J2TA Glaucoma/ocular hypertension 9C61 Approved [210]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [169]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [214]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [216]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [218]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [219]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [220]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A3 (ANXA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C-C motif chemokine 2 (CCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [203]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Gefitinib DM15F0X Colon adenocarcinoma Approved [222]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [223]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [224]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [225]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [226]
Quercetin DM3NC4M Obesity 5B81 Approved [227]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [229]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [230]
Methotrexate DM2TEOL Anterior urethra cancer Approved [231]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [232]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [233]
Quercetin DM3NC4M Obesity 5B81 Approved [234]
Fructose DM43AN2 Vomiting MD90 Approved [235]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [236]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [230]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [237]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [238]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [200]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [240]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [207]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [241]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [242]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [243]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [244]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [245]
Capsaicin DMGMF6V Back pain ME84.Z Approved [246]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [247]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD(P)H dehydrogenase 1 (NQO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [248]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [250]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [251]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [252]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [253]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [254]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [256]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [257]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [258]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [259]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [261]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [262]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-3 (CDH3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Selenium DM25CGV N. A. N. A. Approved [140]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [265]
Folic Acid DMEMBJC Colorectal carcinoma Approved [266]
Menthol DMG2KW7 Back pain ME84.Z Approved [267]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tenascin (TNC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [268]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [270]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [271]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Capsaicin DMGMF6V Back pain ME84.Z Approved [272]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [273]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nitric oxide synthase 1 (NOS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [275]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Testosterone DM7HUNW Hot flushes GA30 Approved [276]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [277]
Menthol DMG2KW7 Back pain ME84.Z Approved [267]
Capsaicin DMGMF6V Back pain ME84.Z Approved [278]
Bortezomib DMNO38U Leukemia Approved [279]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [280]
Interferon gamma-1b DMWUMRL Chronic granulomatous disease 4A00.0Y Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein PML (PML)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [281]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [200]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Menthol DMG2KW7 Back pain ME84.Z Approved [267]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [282]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [282]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [283]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Menthol DMG2KW7 Back pain ME84.Z Approved [267]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [285]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [286]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [287]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [287]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [288]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [169]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [289]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [290]
Terbinafine DMI6HUW Fungal infection 1F29-1F2F Approved [291]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [289]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [292]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [293]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FosB (FOSB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [294]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [143]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [296]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [265]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [297]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fractalkine (CX3CL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Fructose DM43AN2 Vomiting MD90 Approved [235]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [299]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [300]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [301]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [303]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [228]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [304]
paraquat DMR8O3X Discovery agent N.A. Investigative [305]
⏷ Show the Full List of 9 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [283]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [306]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [307]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [308]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [309]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Desmocollin-1 (DSC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [218]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [136]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [310]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [311]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Corneodesmosin (CDSN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [161]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [312]
Milchsaure DM462BT Pruritus EC90 Investigative [157]
⏷ Show the Full List of 6 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Urethane DM7NSI0 N. A. N. A. Phase 4 [163]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [313]
Okadaic acid DM47CO1 Discovery agent N.A. Investigative [314]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [273]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [315]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [171]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [304]
⏷ Show the Full List of 8 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [265]
Folic Acid DMEMBJC Colorectal carcinoma Approved [176]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [317]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [262]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [162]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [318]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [319]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
Milchsaure DM462BT Pruritus EC90 Investigative [157]
⏷ Show the Full List of 8 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [321]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
Arsenic DMTL2Y1 N. A. N. A. Approved [209]
Urethane DM7NSI0 N. A. N. A. Phase 4 [163]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [322]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
⏷ Show the Full List of 7 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [265]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [262]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [323]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [262]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
⏷ Show the Full List of 7 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [207]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [207]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [324]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [319]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfotransferase 1E1 (SULT1E1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [325]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [325]
Methotrexate DM2TEOL Anterior urethra cancer Approved [326]
Estrone DM5T6US Acne vulgaris ED80 Approved [327]
Dienestrol DMBSXI0 Atrophic vaginitis GA30.2 Approved [327]
Ethanol DMDRQZU Chronic pain MG30 Approved [328]
Folic Acid DMEMBJC Colorectal carcinoma Approved [176]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [329]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [218]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [327]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [17]
Diazepam DM08E9O Alcohol withdrawal Approved [330]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [331]
Desogestrel DM27U4Y Contraception QA21 Approved [331]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [17]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [17]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [332]
Quercetin DM3NC4M Obesity 5B81 Approved [333]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [17]
Diazepam DM08E9O Alcohol withdrawal Approved [330]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [334]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [335]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [17]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [17]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [337]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Progesterone DMUY35B Amenorrhea GA20.0 Approved [338]
Meclofenamic acid DM05FXR Ankylosing spondylitis FA92.0 Approved [17]
Diazepam DM08E9O Alcohol withdrawal Approved [330]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [339]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [17]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [17]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [172]
Glimepiride DM5FSJA Diabetic complication 5A2Y Approved [340]
Ethacrynic acid DM60QMR Edema MG29 Approved [339]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [17]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Folic Acid DMEMBJC Colorectal carcinoma Approved [176]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [14]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [170]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [341]
⏷ Show the Full List of 9 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [307]
Haloperidol DM96SE0 Delirium Approved [342]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [299]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [344]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [345]
Fluoxetine DM3PD2C Bipolar depression Approved [346]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [347]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [348]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [347]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cochlin (COCH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [14]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [294]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [350]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [351]
Methotrexate DM2TEOL Anterior urethra cancer Approved [142]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [296]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [301]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [353]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [354]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Ethanol DMDRQZU Chronic pain MG30 Approved [355]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [357]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [336]
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [358]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [360]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [361]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [362]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [242]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [363]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [364]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein AMBP (AMBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [365]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [366]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [367]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Benazepril DMH1M9B Hypertension BA00-BA04 Approved [368]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [162]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [138]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Methotrexate DM2TEOL Anterior urethra cancer Approved [370]
Quercetin DM3NC4M Obesity 5B81 Approved [371]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [347]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [372]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [373]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Selenium DM25CGV N. A. N. A. Approved [140]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [374]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [243]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [375]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [376]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [377]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [378]
Paclitaxel DMLB81S Breast carcinoma Approved [379]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [380]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [381]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [382]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [383]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [384]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [384]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [384]
Capsaicin DMGMF6V Back pain ME84.Z Approved [385]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [386]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [387]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [388]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [389]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [390]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-enolase (ENO1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [391]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Methotrexate DM2TEOL Anterior urethra cancer Approved [370]
Quercetin DM3NC4M Obesity 5B81 Approved [371]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [337]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [392]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [393]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [394]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [394]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Asparagine synthetase (ASNS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [294]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [395]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [396]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [395]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [397]
Fluoxetine DM3PD2C Bipolar depression Approved [395]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [274]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [398]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [399]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [400]
Ethanol DMDRQZU Chronic pain MG30 Approved [401]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [402]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [403]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [404]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [405]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [406]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [407]
Naloxone DM3FXMA Narcotic depression 6A7Z Approved [408]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [409]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [410]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [411]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [412]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [342]
Ofloxacin DM0VQN3 Acute gonococcal cervicitis Approved [413]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [414]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [413]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.2 (H1-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [415]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [416]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [14]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [350]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [417]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Selenium DM25CGV N. A. N. A. Approved [140]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [418]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [419]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [420]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [421]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [422]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor E3 (TFE3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [423]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [424]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Selenium DM25CGV N. A. N. A. Approved [425]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [426]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [427]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [428]
Acitretin DM8BKU9 Psoriasis vulgaris EA90 Approved [429]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [430]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Iduronate 2-sulfatase (IDS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [301]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [274]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [334]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [431]
Methotrexate DM2TEOL Anterior urethra cancer Approved [432]
Epinephrine DM3KJBC Acute asthma CA23 Approved [433]
Quercetin DM3NC4M Obesity 5B81 Approved [410]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [434]
Fructose DM43AN2 Vomiting MD90 Approved [235]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [274]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [394]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [435]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [207]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [162]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [436]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [394]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Folic Acid DMEMBJC Colorectal carcinoma Approved [152]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [437]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Folic Acid DMEMBJC Colorectal carcinoma Approved [176]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [242]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 14-3-3 protein sigma (SFN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Gefitinib DM15F0X Colon adenocarcinoma Approved [438]
Methotrexate DM2TEOL Anterior urethra cancer Approved [439]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [440]
Quercetin DM3NC4M Obesity 5B81 Approved [441]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [440]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [442]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [443]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [422]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [444]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [445]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [446]
Quercetin DM3NC4M Obesity 5B81 Approved [447]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [241]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [448]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [449]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [434]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [450]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [451]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [452]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [321]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [392]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [343]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [216]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [453]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [454]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [392]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [455]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [456]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [394]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [353]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [114]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [366]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dipeptidyl peptidase 1 (CTSC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [304]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Folic Acid DMEMBJC Colorectal carcinoma Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ataxin-1 (ATXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Selenium DM25CGV N. A. N. A. Approved [140]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [361]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [457]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [265]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [14]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [458]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [459]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [383]
Gefitinib DM15F0X Colon adenocarcinoma Approved [460]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [461]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [187]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [462]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [463]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Selenium DM25CGV N. A. N. A. Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [242]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [113]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [442]
Estrone DM5T6US Acne vulgaris ED80 Approved [463]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [436]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Reserpine DM6VM38 Hypertension BA00-BA04 Approved [89]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [14]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [464]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [259]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [465]
Verapamil DMA7PEW Angina pectoris BA40 Approved [466]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [350]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [250]
Selenium DM25CGV N. A. N. A. Approved [140]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [467]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [253]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [195]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [468]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [469]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [470]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [471]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [472]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [351]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [473]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [474]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein D53 (TPD52L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Testosterone enanthate DMB6871 N. A. N. A. Approved [316]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [475]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [358]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [304]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RRP12-like protein (RRP12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [142]
Quercetin DM3NC4M Obesity 5B81 Approved [313]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Exemestane DM9HPW3 Hormonally-responsive breast cancer 2C60-2C65 Approved [476]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [477]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [478]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dipeptidyl peptidase 9 (DPP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [479]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Arsenic DMTL2Y1 N. A. N. A. Approved [209]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [318]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [318]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [480]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [216]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [423]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [481]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pantothenate kinase 1 (PANK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [104]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [273]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [304]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Methotrexate DM2TEOL Anterior urethra cancer Approved [283]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [482]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [364]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM89A (FAM89A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [219]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [255]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [483]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [483]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Perilipin-2 (PLIN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [439]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [242]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [484]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [207]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [294]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [334]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [361]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Quercetin DM3NC4M Obesity 5B81 Approved [469]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [485]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [486]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [487]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [321]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
Bortezomib DMNO38U Leukemia Approved [479]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [89]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [347]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfiredoxin-1 (SRXN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [488]
Ethacrynic acid DM60QMR Edema MG29 Approved [489]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [394]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [207]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [490]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [491]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [492]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [493]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [173]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [494]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [495]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [496]
⏷ Show the Full List of 8 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [414]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [169]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [14]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [14]
Arsenic DMTL2Y1 N. A. N. A. Approved [209]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [318]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Lumiracoxib DM1S4AG Chronic renal failure GB61.Z Approved [185]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [185]
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [497]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Fluoxetine DM3PD2C Bipolar depression Approved [394]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [313]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [14]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [14]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [477]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [492]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein piccolo (PCLO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [217]
Arsenic DMTL2Y1 N. A. N. A. Approved [209]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [255]
Urethane DM7NSI0 N. A. N. A. Phase 4 [163]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [319]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [492]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [149]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [475]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [498]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [353]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Ampicillin DMHWE7P Acute epiglottitis Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [499]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [500]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [501]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [502]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [503]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
2-deoxyglucose DMIAHVU Solid tumour/cancer 2A00-2F9Z Approved [504]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Methotrexate DM2TEOL Anterior urethra cancer Approved [283]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [505]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [14]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [506]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [507]
Fructose DM43AN2 Vomiting MD90 Approved [89]
Ketoprofen DMRKXPT Bursitis Approved [89]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [508]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [509]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [510]
Gefitinib DM15F0X Colon adenocarcinoma Approved [511]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [512]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [359]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [513]
Etretinate DM2CZFA Keratosis ED56 Approved [514]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [515]
Methotrexate DM2TEOL Anterior urethra cancer Approved [283]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [516]
Quercetin DM3NC4M Obesity 5B81 Approved [517]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [518]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [519]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [301]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [263]
Selenium DM25CGV N. A. N. A. Approved [140]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [520]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [521]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [522]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [442]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [523]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [524]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [524]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [89]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [525]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [526]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [527]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [528]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [529]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [530]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [225]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [531]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [532]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [533]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [534]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Momelotinib DMF98Q0 Myelofibrosis 2A20.2 Approved [535]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [536]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [104]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [537]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [538]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [104]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A2 (ANXA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [345]
Quercetin DM3NC4M Obesity 5B81 Approved [188]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [539]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [540]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [541]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [191]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thrombospondin-1 (THBS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [436]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [194]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [295]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [184]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [542]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [543]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [544]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [175]
Oxaprozin DM9UB0P Osteoarthritis FA00-FA05 Approved [545]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromelysin-1 (MMP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [89]
Fluvastatin DM4MDJY Arteriosclerosis BD40 Approved [89]
Pravastatin DM6A0X7 Adult acute monocytic leukemia Approved [89]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [89]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [546]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [180]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [515]
Methotrexate DM2TEOL Anterior urethra cancer Approved [547]
Quercetin DM3NC4M Obesity 5B81 Approved [548]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [518]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Galectin-1 (LGALS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [453]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [237]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [190]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [549]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [538]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [550]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [294]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [350]
Gefitinib DM15F0X Colon adenocarcinoma Approved [551]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [334]
Selenium DM25CGV N. A. N. A. Approved [140]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [134]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [402]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [350]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [396]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [414]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Quercetin DM3NC4M Obesity 5B81 Approved [552]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [453]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [537]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [553]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [452]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [151]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [15]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [299]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Platelet glycoprotein 4 (CD36)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [403]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [554]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [555]
Tolcapone DM8MNVO Parkinson disease 8A00.0 Approved [444]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [556]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [159]
Asasantin DMCZIHT Cerebrovascular ischaemia 8B1Z Approved [557]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [194]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [16]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [194]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [452]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [558]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [356]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [370]
Quercetin DM3NC4M Obesity 5B81 Approved [371]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [559]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [560]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [561]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [562]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [563]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxiredoxin-6 (PRDX6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [564]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Ethanol DMDRQZU Chronic pain MG30 Approved [565]
Capsaicin DMGMF6V Back pain ME84.Z Approved [566]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [239]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [567]
Arsenic DMTL2Y1 N. A. N. A. Approved [568]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxiredoxin-2 (PRDX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [569]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Quercetin DM3NC4M Obesity 5B81 Approved [133]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [570]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [114]
Repaglinide DM5SXUV Diabetic complication 5A2Y Approved [571]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [301]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [572]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [255]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [273]
Benzoic Acid DMKB9FI Alopecia areata ED70.2 Approved [573]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [574]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [206]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [575]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [576]
Quercetin DM3NC4M Obesity 5B81 Approved [577]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [578]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [435]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [249]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Clavulanate DM2FGRT Bacteremia 1A73 Approved [575]
Quercetin DM3NC4M Obesity 5B81 Approved [579]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [181]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [343]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [442]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [580]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [581]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fatty acid synthase (FASN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [582]
Selenium DM25CGV N. A. N. A. Approved [140]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [583]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [403]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [584]
Quercetin DM3NC4M Obesity 5B81 Approved [436]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [585]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [348]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-secretase 1 (BACE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [402]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [192]
Quercetin DM3NC4M Obesity 5B81 Approved [586]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [189]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [264]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [587]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
TRIENTINE DMD2WPG Inborn error of metabolism 5C50-5C59 Approved [588]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [140]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Methotrexate DM2TEOL Anterior urethra cancer Approved [370]
Quercetin DM3NC4M Obesity 5B81 Approved [552]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [191]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [538]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [414]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Clozapine DMFC71L Schizophrenia 6A20 Approved [342]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [285]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [589]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [490]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [590]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [345]
Etretinate DM2CZFA Keratosis ED56 Approved [369]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [591]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [538]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [115]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [592]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [593]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [593]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [594]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [595]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [593]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [593]
Ethacrynic acid DM60QMR Edema MG29 Approved [593]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [593]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [596]
Quercetin DM3NC4M Obesity 5B81 Approved [597]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [598]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [599]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [600]
Testosterone DM7HUNW Hot flushes GA30 Approved [601]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [503]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 4A11 (CYP4A11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [602]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [603]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [603]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [198]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [136]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [136]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [603]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [603]
Oxaprozin DM9UB0P Osteoarthritis FA00-FA05 Approved [603]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plectin (PLEC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [342]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [149]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Selenium DM25CGV N. A. N. A. Approved [140]
Quercetin DM3NC4M Obesity 5B81 Approved [552]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [352]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [150]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [14]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [14]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [284]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [428]
Testosterone DM7HUNW Hot flushes GA30 Approved [213]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [138]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [604]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [605]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [257]
Arsenic DMTL2Y1 N. A. N. A. Approved [209]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [606]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ELAV-like protein 1 (ELAVL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [269]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [607]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [353]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [536]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [608]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [302]
Amsacrine DMZKYIV Acute lymphoblastic leukaemia 2A85 Approved [609]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [610]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [611]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [612]
Prednisone DM2HG4X Acute asthma CA23 Approved [613]
Triamterene DM2HU9I Congestive heart failure BD10 Approved [613]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [614]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [615]
Epinephrine DM3KJBC Acute asthma CA23 Approved [616]
Quercetin DM3NC4M Obesity 5B81 Approved [410]
Fluoxetine DM3PD2C Bipolar depression Approved [346]
Romiplostim DM3U7SZ Thrombocytopenia 3B64 Approved [617]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [414]
Probenecid DMMFWOJ Acute gonococcal cervicitis Approved [618]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [619]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [313]
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [620]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Quercetin DM3NC4M Obesity 5B81 Approved [112]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [423]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [458]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [621]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [260]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [255]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [139]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [622]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [166]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [139]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [623]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [561]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [156]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [624]
Milchsaure DM462BT Pruritus EC90 Investigative [157]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [345]
Methotrexate DM2TEOL Anterior urethra cancer Approved [126]
Quercetin DM3NC4M Obesity 5B81 Approved [625]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [347]
Panobinostat DM58WKG Chronic graft versus host disease Approved [138]
Leflunomide DMR8ONJ Arthritis FA20 Approved [145]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [215]
Ketorolac DMI4EL5 Postoperative inflammation 1A00-CA43.1 Approved [626]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA (DNMT3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [627]
Methotrexate DM2TEOL Anterior urethra cancer Approved [119]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [628]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [629]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [630]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [221]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [131]
Ethanol DMDRQZU Chronic pain MG30 Approved [631]
Folic Acid DMEMBJC Colorectal carcinoma Approved [632]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [160]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [633]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [634]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [635]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [445]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [132]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [636]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [637]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [185]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [638]
⏷ Show the Full List of 10 Drug(s)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Procainamide DMNMXR8 Ventricular arrhythmias BC71 Approved [639]
Hydralazine DMU8JGH Chronic heart failure BD1Z Approved [640]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [641]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [642]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [643]
Quercetin DM3NC4M Obesity 5B81 Approved [644]
Testosterone DM7HUNW Hot flushes GA30 Approved [151]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [116]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [304]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lymphotoxin-alpha (LTA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [134]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [228]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [168]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [645]
Arsenic DMTL2Y1 N. A. N. A. Approved [646]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [647]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [648]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [649]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [650]
⏷ Show the Full List of 10 Drug(s)

Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
C-X-C chemokine receptor type 1 (CXCR1) TTMWT8Z CXCR1_HUMAN Inhibitor [3]
C-X-C chemokine receptor type 2 (CXCR2) TT30C9G CXCR2_HUMAN Inhibitor [3]
Interleukin-8 (IL8) TTCTE1G IL8_HUMAN Inhibitor [4]
Prostaglandin G/H synthase 2 (COX-2) TTVKILB PGH2_HUMAN Inhibitor [5]

Drug Transporter (DTP)
DTP Name DTP ID UniProt ID MOA REF
Probable small intestine urate exporter (SLC17A4) DTHE530 S17A4_HUMAN Substrate [6]
Monocarboxylate transporter 2 (SLC16A7) DTLT3UG MOT2_HUMAN Substrate [7]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Substrate [8]
Cytochrome P450 2C9 (CYP2C9) Main DME DE5IED8 CP2C9_HUMAN Substrate [9]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Substrate [9]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Substrate [10]
UDP-glucuronosyltransferase 2B7 (UGT2B7) DEB3CV1 UD2B7_HUMAN Substrate [11]
UDP-glucuronosyltransferase 1A9 (UGT1A9) DE85D2P UD19_HUMAN Substrate [11]
UDP-glucuronosyltransferase 1A3 (UGT1A3) DEF2WXN UD13_HUMAN Substrate [11]
Acyl-CoA thioesterase 2 (ACOT2) DEMEPVJ ACOT2_HUMAN Substrate [12]
Alpha-methylacyl-CoA racemase (AMACR) DEGKWJB AMACR_HUMAN Substrate [13]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
(Lyso)-N-acylphosphatidylethanolamine lipase (ABHD4) OTQK3M9X ABHD4_HUMAN Gene/Protein Processing [14]
1,4-alpha-glucan-branching enzyme (GBE1) OTK2N05B GLGB_HUMAN Gene/Protein Processing [14]
14-3-3 protein sigma (SFN) OTLJCZ1U 1433S_HUMAN Gene/Protein Processing [14]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Gene/Protein Processing [15]
5'-AMP-activated protein kinase subunit beta-2 (PRKAB2) OTLVN68B AAKB2_HUMAN Gene/Protein Processing [14]
A disintegrin and metalloproteinase with thrombospondin motifs 8 (ADAMTS8) OT2KFY1S ATS8_HUMAN Gene/Protein Processing [16]
Adenylate cyclase type 1 (ADCY1) OTSLLFZO ADCY1_HUMAN Gene/Protein Processing [14]
Adenylate kinase 4, mitochondrial (AK4) OTA0T02Q KAD4_HUMAN Gene/Protein Processing [14]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Gene/Protein Processing [17]
Aldo-keto reductase family 1 member C2 (AKR1C2) OTQ2XMO3 AK1C2_HUMAN Gene/Protein Processing [17]

References

1 Ibuprofen FDA Label
2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2713).
3 2-Arylpropionic CXC chemokine receptor 1 (CXCR1) ligands as novel noncompetitive CXCL8 inhibitors. J Med Chem. 2005 Jun 30;48(13):4312-31.
4 Structure-Activity Relationship of novel phenylacetic CXCR1 inhibitors. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4026-30.
5 Maternal toxicity of nonsteroidal anti-inflammatory drugs as an important factor affecting prenatal development. Reprod Toxicol. 2009 Sep;28(2):239-44.
6 A Na+-phosphate cotransporter homologue (SLC17A4 protein) is an intestinal organic anion exporter. Am J Physiol Cell Physiol. 2012 Jun 1;302(11):C1652-60.
7 Monocarboxylate Transporters in Drug Disposition: Role in the Toxicokinetics and Toxicodynamics of the Drug of Abuse GHB.
8 PharmGKB summary: ibuprofen pathways. Pharmacogenet Genomics. 2015 Feb;25(2):96-106.
9 Summary of information on human CYP enzymes: human P450 metabolism data. Drug Metab Rev. 2002 Feb-May;34(1-2):83-448.
10 Influence of CYP2C8 polymorphisms on the hydroxylation metabolism of paclitaxel, repaglinide and ibuprofen enantiomers in vitro. Biopharm Drug Dispos. 2013 Jul;34(5):278-87.
11 Substrates, inducers, inhibitors and structure-activity relationships of human Cytochrome P450 2C9 and implications in drug development. Curr Med Chem. 2009;16(27):3480-675.
12 A study on the chiral inversion of mandelic acid in humans. Org Biomol Chem. 2014 Sep 14;12(34):6737-44.
13 Ibuprofen: pharmacology, efficacy and safety. Inflammopharmacology. 2009 Dec;17(6):275-342.
14 Transcriptomics hit the target: monitoring of ligand-activated and stress response pathways for chemical testing. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):7-18.
15 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) is up-regulated by flurbiprofen and other non-steroidal anti-inflammatory drugs in human colon cancer HT29 cells. Arch Biochem Biophys. 2009 Jul 15;487(2):139-45. doi: 10.1016/j.abb.2009.05.017. Epub 2009 Jun 6.
16 Rofecoxib modulates multiple gene expression pathways in a clinical model of acute inflammatory pain. Pain. 2007 Mar;128(1-2):136-47.
17 Type 5 17beta-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3): role in breast cancer and inhibition by non-steroidal anti-inflammatory drug analogs. Chem Biol Interact. 2009 Mar 16;178(1-3):221-7.
18 Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA)
19 Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer Models. Clin Cancer Res. 2020 Mar 15;26(6):1420-1431.
20 Fully humanized neutralizing antibodies to interleukin-8 (ABX-IL8) inhibit angiogenesis, tumor growth, and metastasis of human melanoma. Am J Pathol. 2002 Jul;161(1):125-34.
21 Phase I trial of HuMax-IL8 (BMS-986253), an anti-IL-8 monoclonal antibody, in patients with metastatic or unresectable solid tumors. J Immunother Cancer. 2019 Sep 5;7(1):240.
22 Company report (Genmab)
23 Mode of action of clotrimazole: implications for therapy. Am J Obstet Gynecol. 1985 Aug 1;152(7 Pt 2):939-44.
24 CXCR2 Antagonist MK-7123.A Phase 2 Proof-of-Concept Trial for Chronic Obstructive Pulmonary Disease.Am J Respir Crit Care Med.2015 May 1;191(9):1001-11.
25 Emerging drugs for the treatment of chronic obstructive pulmonary disease. Expert Opin Emerg Drugs. 2006 May;11(2):275-91.
26 Pharmacological characterization of AZD5069, a slowly reversible CXC chemokine receptor 2 antagonist. J Pharmacol Exp Ther. 2015 May;353(2):340-50.
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