Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMHYLQ2)

Drug Name
Lithium chloride Drug Info
Synonyms
LITHIUM CHLORIDE; 7447-41-8; Lithiumchloride; Lithium chloride (LiCl); LiCl; chlorure de lithium; Chlorku litu; chlorolithium; Lithiumchlorid; Chlorku litu [Polish]; Luthium chloride; Chlorure de lithium [French]; CCRIS 5924; UNII-G4962QA067; HSDB 4281; EINECS 231-212-3; lithium(1+) ion chloride; NSC 327172; CHEMBL69710; CHEBI:48607; NSC327172; MFCD00011078; G4962QA067; Lithium chloride, 99%, extra pure; ClLi; Lithium chloride, 99+%, ACS reagent; Lithium chloride, 99%, for molecular biology; Lithium chloride, 99%, for analysis, anhyd
Indication
Disease Entry ICD 11 Status REF
Discovery agent N.A. Investigative [1]
Cross-matching ID
PubChem CID
433294
ChEBI ID
CHEBI:48607
CAS Number
CAS 7447-41-8
TTD Drug ID
DMHYLQ2

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DOT
Drug Status:
Approved Drug(s)
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Preclinical Drug(s)
Discontinued Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting Glycogen synthase kinase-3 alpha (GSK-3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [5]
LY2090314 DMTBFE4 Acute myeloid leukaemia 2A60 Phase 2 [6]
Lithium DMZ3OU6 Bipolar disorder 6A60 Phase 2 [7]
KENPAULLONE DMAGVXW Discovery agent N.A. Patented [6]
CHIR-99021 DMB8MNU Allergic inflammation 4A80-4A85 Patented [6]
TDZD-8 DMG6Q45 Malignant glioma 2A00.0 Patented [6]
AR-A014418 DMUPN01 Ovarian cancer 2C73 Patented [6]
PMID27828716-Compound-21 DMO1NAR N. A. N. A. Patented [6]
Thiadiazolidindione derivative 2 DM5AUL0 N. A. N. A. Patented [6]
PMID27828716-Compound-18 DMNR6KL N. A. N. A. Patented [6]
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Drug(s) Affected By Cyclic AMP-responsive element-binding protein 1 (CREB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [8]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [9]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [10]
Selenium DM25CGV N. A. N. A. Approved [11]
Methotrexate DM2TEOL Anterior urethra cancer Approved [12]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [13]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [14]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [14]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [15]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [16]
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Drug(s) Affected By Apoptosis regulator Bcl-2 (BCL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [17]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [18]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [19]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [20]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [21]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Verapamil DMA7PEW Angina pectoris BA40 Approved [23]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [24]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [25]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [26]
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Drug(s) Affected By Paired box protein Pax-3 (PAX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [27]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [28]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [28]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [28]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [30]
Dabigatran DMDI6R4 Stroke 8B20 Approved [28]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [28]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [32]
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Drug(s) Affected By Glycogen synthase kinase-3 beta (GSK3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [33]
Gefitinib DM15F0X Colon adenocarcinoma Approved [34]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [35]
Selenium DM25CGV N. A. N. A. Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [36]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [37]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [39]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [41]
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Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [42]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [43]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [44]
Selenium DM25CGV N. A. N. A. Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [45]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [47]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [48]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [49]
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Drug(s) Affected By Homeobox protein SIX1 (SIX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [54]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
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Drug(s) Affected By Acetylcholinesterase (ACHE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetylcholine DMDF79Z Cataract 9B10 Approved [59]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [60]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [61]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [63]
L-Glutamic Acid DM4PUDW Schizophrenia 6A20 Approved [61]
Tacrine DM51FY6 Alzheimer disease 8A20 Approved [64]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [65]
Neostigmine DM6T2J3 Myasthenia gravis 8C6Y Approved [66]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
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Drug(s) Affected By Cell division cycle 7-related protein kinase (CDC7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [71]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [73]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [74]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [75]
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Drug(s) Affected By Pyridoxal kinase (PDXK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Bortezomib DMNO38U Leukemia Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
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Drug(s) Affected By Cdc42 effector protein 2 (CDC42EP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [87]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [89]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
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Drug(s) Affected By Dihydroxyacetone phosphate acyltransferase (GNPAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [92]
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Drug(s) Affected By Transmembrane protease serine 2 (TMPRSS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [93]
Diazepam DM08E9O Alcohol withdrawal Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Selenium DM25CGV N. A. N. A. Approved [11]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [93]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [93]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [93]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [93]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [93]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [93]
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Drug(s) Affected By Intermediate conductance calcium-activated potassium channel protein 4 (KCNN4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Chlorzoxazone DMCYVDT Acute pain MG31 Approved [95]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Charybdotoxin DMKN345 Scorpion envenoming syndrome 8D43 Approved [96]
Clotrimazole DMMFCIH Cutaneous candidiasis 1F23.14 Approved [95]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [97]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [99]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [100]
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Drug(s) Affected By Heat shock 70 kDa protein 12A (HSPA12A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
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Drug(s) Affected By Phospholipid phosphatase 2 (PLPP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Paclitaxel DMLB81S Breast carcinoma Approved [108]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [109]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [110]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [111]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
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Drug(s) Affected By Microphthalmia-associated transcription factor (MITF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [9]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [113]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [115]
Vemurafenib DM62UG5 Melanoma 2C30 Approved [116]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
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Drug(s) Affected By Kelch repeat and BTB domain-containing protein 11 (KBTBD11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [119]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [120]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
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Drug(s) Affected By CUGBP Elav-like family member 2 (CELF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Selenium DM25CGV N. A. N. A. Approved [11]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [123]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Menthol DMG2KW7 Back pain ME84.Z Approved [125]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
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Drug(s) Affected By Netrin-1 (NTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [127]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [128]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
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Drug(s) Affected By Adenomatous polyposis coli protein 2 (APC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Arsenic DMTL2Y1 N. A. N. A. Approved [130]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [131]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [132]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
UNC0379 DMD1E4J Hepatocellular carcinoma 2C12.02 Preclinical [133]
AHPN DM8G6O4 Discovery agent N.A. Investigative [134]
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Drug(s) Affected By Histone-lysine N-methyltransferase NSD2 (NSD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [137]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [73]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
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Drug(s) Affected By Complement factor D (CFD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [140]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ethanol DMDRQZU Chronic pain MG30 Approved [141]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [142]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
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Drug(s) Affected By Intercellular adhesion molecule 1 (ICAM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Erythromycin DM4K7GQ Acne vulgaris ED80 Approved [143]
Dicloxacillin DM8EU0Z Bacterial infection 1A00-1C4Z Approved [143]
Ergonovine DM0VEC1 Postpartum haemorrhage JA43 Approved [21]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [144]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [145]
Mizolastine DM1FDN8 Allergic rhinitis CA08.0 Approved [146]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [147]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [148]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [149]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [150]
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Drug(s) Affected By Keratin, type I cytoskeletal 19 (KRT19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [94]
Selenium DM25CGV N. A. N. A. Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [152]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [152]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
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Drug(s) Affected By Tropomyosin alpha-1 chain (TPM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Etretinate DM2CZFA Keratosis ED56 Approved [156]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [157]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Bortezomib DMNO38U Leukemia Approved [80]
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Drug(s) Affected By Heme oxygenase 1 (HMOX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [142]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [159]
Verapamil DMA7PEW Angina pectoris BA40 Approved [160]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [161]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Selenium DM25CGV N. A. N. A. Approved [163]
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [150]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [164]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
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Drug(s) Affected By Microtubule-associated protein tau (MAPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [33]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [165]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [166]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [37]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
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Drug(s) Affected By Alkaline phosphatase, germ cell type (ALPG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [167]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [168]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [169]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [170]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [167]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [171]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [172]
Hydroxyestradiol DMJXQME N. A. N. A. Investigative [169]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [173]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hyaluronan and proteoglycan link protein 1 (HAPLN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [99]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [174]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [29]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [175]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [29]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [176]
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Drug(s) Affected By Laminin subunit gamma-1 (LAMC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [137]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Indomethacin DMSC4A7 Bursitis Approved [179]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [180]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Coagulation factor V (F5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [181]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [183]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cystic fibrosis transmembrane conductance regulator (CFTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivacaftor DMZC1HS Cystic fibrosis CA25 Approved [184]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Rhucin DM3ADGP Erectile dysfunction HA01.1 Approved [185]
Quercetin DM3NC4M Obesity 5B81 Approved [186]
Miglustat DM5J64S Niemann-Pick disease type C Approved [187]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [188]
Milrinone DM8TUPF Congestive heart failure BD10 Approved [185]
Oxidized glutathione DM9EQC0 Breast cancer 2C60-2C65 Approved [189]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
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Drug(s) Affected By Metallothionein-1G (MT1G)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [193]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Motexafin gadolinium DMEJKRF Brain cancer 2A00 Approved [194]
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Drug(s) Affected By Plastin-2 (LCP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [196]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [197]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
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Drug(s) Affected By Acylamino-acid-releasing enzyme (APEH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [198]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Troponin T, slow skeletal muscle (TNNT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [199]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [200]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [201]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [54]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [202]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [201]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-1,4-galactosyltransferase 1 (B4GALT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [203]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [204]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [204]
Estriol DMOEM2I Hormone deficiency 5A61.1 Approved [204]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CD44 antigen (CD44)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [206]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Selenium DM25CGV N. A. N. A. Approved [207]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [208]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [209]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [210]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [211]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-2 (CDH2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [213]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [214]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [215]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [216]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [217]
Testosterone DM7HUNW Hot flushes GA30 Approved [218]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [219]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanine nucleotide-binding protein G(z) subunit alpha (GNAZ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Arachidonate 5-lipoxygenase-activating protein (ALOX5AP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [220]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [221]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [80]
Warfarin DMJYCVW Atrial fibrillation BC81.3 Approved [223]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By B-cell lymphoma 3 protein (BCL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [224]
Selenium DM25CGV N. A. N. A. Approved [11]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [225]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [155]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [155]
Menthol DMG2KW7 Back pain ME84.Z Approved [125]
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Drug(s) Affected By Receptor tyrosine-protein kinase erbB-3 (ERBB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [226]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [227]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [30]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [201]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [228]
Chloroquine DMSI5CB Malaria 1F40-1F45 Approved [229]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Iduronate 2-sulfatase (IDS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [220]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [155]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pentraxin-related protein PTX3 (PTX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [230]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [231]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [73]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [232]
Bortezomib DMNO38U Leukemia Approved [233]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5-hydroxytryptamine receptor 2A (HTR2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [21]
Fluphenazine DMIT8LX Psychotic disorder 6A20-6A25 Approved [234]
Paliperidone DM7NPJS Psychotic disorder 6A20-6A25 Approved [235]
Haloperidol DM96SE0 Delirium Approved [235]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Olanzapine DMPFN6Y Bipolar depression Approved [236]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [237]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [238]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Progranulin (GRN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [239]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [180]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein S100-A3 (S100A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [240]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amiloride-sensitive sodium channel subunit alpha (SCNN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [242]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Testosterone DM7HUNW Hot flushes GA30 Approved [243]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [244]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By TGF-beta receptor type-2 (TGFBR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [245]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [12]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [246]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [177]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Peroxisome proliferator-activated receptor gamma (PPARG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [247]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Quercetin DM3NC4M Obesity 5B81 Approved [249]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [138]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [250]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [251]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [252]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [253]
Stavudine DM6DEK9 Human immunodeficiency virus infection 1C62 Approved [254]
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Drug(s) Affected By Alpha-synuclein (SNCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [137]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [120]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Bortezomib DMNO38U Leukemia Approved [255]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [256]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [104]
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Drug(s) Affected By Melanocyte protein PMEL (PMEL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [257]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Vemurafenib DM62UG5 Melanoma 2C30 Approved [116]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [137]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [127]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
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Drug(s) Affected By Signal transducer and activator of transcription 6 (STAT6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [258]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [259]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [260]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [258]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Prednisone DM2HG4X Acute asthma CA23 Approved [262]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [263]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [264]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [265]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [266]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [267]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [268]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 4 inhibitor B (CDKN2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Gefitinib DM15F0X Colon adenocarcinoma Approved [269]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Prednisone DM2HG4X Acute asthma CA23 Approved [262]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [270]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [271]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurogenic locus notch homolog protein 1 (NOTCH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [272]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [273]
Propranolol DM79NTF Angina pectoris BA40 Approved [274]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [275]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [276]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Mebendazole DMO14SG Ascariasis 1F62 Approved [277]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adhesion G protein-coupled receptor E5 (ADGRE5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [278]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [279]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [280]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Paxillin (PXN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [281]
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [282]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [283]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [2]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [284]
Terbinafine DMI6HUW Fungal infection 1F29-1F2F Approved [285]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-4 (CASP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [286]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [287]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [288]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [290]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [291]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCAAT/enhancer-binding protein delta (CEBPD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [292]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [293]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Annexin A11 (ANXA11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Ethanol DMDRQZU Chronic pain MG30 Approved [295]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
Methotrexate DM2TEOL Anterior urethra cancer Approved [170]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [296]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [297]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-5 (CASP5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [298]
Menthol DMG2KW7 Back pain ME84.Z Approved [125]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Paclitaxel DMLB81S Breast carcinoma Approved [299]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [300]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
9-hydroxyoctadecadienoic acid DM0FWNJ Discovery agent N.A. Investigative [301]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [300]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitogen-activated protein kinase 10 (MAPK10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Sorbitol DMAN0DE Constipation DD91.1 Approved [302]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [303]
Ethanol DMDRQZU Chronic pain MG30 Approved [295]
Dicumarol DMFQCB1 Bleeding disorder GA20-GA21 Approved [302]
Menthol DMG2KW7 Back pain ME84.Z Approved [125]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [304]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [302]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Estrogen-related receptor gamma (ESRRG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [305]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [246]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [306]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Troponin C, slow skeletal and cardiac muscles (TNNC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [307]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [238]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A1 (CCNA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [220]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [308]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [220]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [309]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [308]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [293]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [310]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Helix-loop-helix protein 1 (NHLH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
Drug(s) Affected By Proteasome activator complex subunit 1 (PSME1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [104]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [87]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [220]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [311]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [120]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [312]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bone marrow stromal antigen 2 (BST2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Methotrexate DM2TEOL Anterior urethra cancer Approved [313]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [313]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Tofacitinib DMBS370 Rheumatoid arthritis FA20 Approved [314]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Kinesin heavy chain isoform 5A (KIF5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [131]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [315]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [316]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
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Drug(s) Affected By Protein AF1q (MLLT11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [317]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [240]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [318]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Bortezomib DMNO38U Leukemia Approved [80]
Bexarotene DMOBIKY Cutaneous T-cell lymphoma 2B01 Approved [319]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phospholipase D1 (PLD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [320]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [321]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [322]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA topoisomerase 3-alpha (TOP3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [323]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [323]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [323]
Adenine DMZLHKJ Malnutrition 5B50-5B71 Approved [323]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
Torcetrapib DMDHYM7 Hyperlipidaemia 5C80 Discontinued in Phase 2 [324]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protein disulfide-isomerase A5 (PDIA5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [155]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [155]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [155]
Adefovir Dipivoxil DMMAWY1 Hepatitis B virus infection 1E51.0 Approved [155]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Platelet-derived growth factor receptor-like protein (PDGFRL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [54]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ecto-NOX disulfide-thiol exchanger 2 (ENOX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
Capsaicin DMGMF6V Back pain ME84.Z Approved [325]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [326]
Phenoxodiol DMBUJVX Ovarian cancer 2C73 Phase 1/2 [326]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [327]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Reticulon-1 (RTN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [328]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [29]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein D53 (TPD52L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [155]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(XIII) chain (COL13A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [329]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [330]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein MEX3B (MEX3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable RNA-binding protein 23 (RBM23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [332]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [333]
Drug(s) Affected By Dynein regulatory complex protein 11 (IQCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [334]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [335]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein FAM90A1 (FAM90A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [336]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
acetaldehyde DMJFKG4 Discovery agent N.A. Investigative [337]
Drug(s) Affected By E3 ubiquitin-protein ligase MIB1 (MIB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [338]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [275]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GRAM domain-containing protein 2A (GRAMD2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [339]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [340]
Drug(s) Affected By cTAGE family member 4 (CTAGE4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [2]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [170]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [336]
Drug(s) Affected By MARVEL domain-containing protein 2 (MARVELD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [336]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (GBGT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [127]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [341]
GALLICACID DM6Y3A0 Discovery agent N.A. Investigative [342]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Myc target protein 1 (MYCT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ethanol DMDRQZU Chronic pain MG30 Approved [295]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [176]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Formylglycine-generating enzyme (SUMF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Probable aminopeptidase NPEPL1 (NPEPL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
THAPSIGARGIN DMDMQIE N. A. N. A. Preclinical [343]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [86]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By sn-1-specific diacylglycerol lipase ABHD11 (ABHD11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [87]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [344]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [170]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [87]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [345]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein phosphatase 1 regulatory subunit 14C (PPP1R14C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [346]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Jun dimerization protein 2 (JDP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ampicillin DMHWE7P Acute epiglottitis Approved [101]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [120]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By FXYD domain-containing ion transport regulator 5 (FXYD5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [246]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [347]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [246]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [104]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Corrinoid adenosyltransferase MMAB (MMAB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [332]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [348]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GRAM domain-containing protein 2B (GRAMD2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [349]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [72]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sperm-associated antigen 5 (SPAG5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [350]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tribbles homolog 3 (TRIB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [246]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [351]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [191]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [352]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [351]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [353]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centrosome-associated protein CEP250 (CEP250)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [92]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Tripartite motif-containing protein 6 (TRIM6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [232]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [175]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [29]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor protein 63 (TP63)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [354]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [355]
Panobinostat DM58WKG Chronic graft versus host disease Approved [356]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [339]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Topotecan DMP6G8T Central nervous system neoplasm Approved [357]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein ILRUN (ILRUN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [358]
Selenium DM25CGV N. A. N. A. Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [30]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [358]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [358]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [359]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinoid-inducible serine carboxypeptidase (SCPEP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [192]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [137]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Bortezomib DMNO38U Leukemia Approved [80]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CDC42 small effector protein 1 (CDC42SE1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [54]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [197]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [360]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-directed RNA polymerase III subunit RPC2 (POLR3B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [104]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Telomeric repeat-binding factor 2-interacting protein 1 (TERF2IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Arsenic DMTL2Y1 N. A. N. A. Approved [361]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [11]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [176]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [362]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Abl interactor 2 (ABI2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [363]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [364]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Formin-2 (FMN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [58]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [29]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sedoheptulokinase (SHPK)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [303]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [364]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Purine-rich element-binding protein gamma (PURG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [220]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [29]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Protein phosphatase 1H (PPM1H)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [74]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [202]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Apoptosis-associated speck-like protein containing a CARD (PYCARD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Selenium DM25CGV N. A. N. A. Approved [11]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [298]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [365]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ethanol DMDRQZU Chronic pain MG30 Approved [366]
Menthol DMG2KW7 Back pain ME84.Z Approved [125]
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Drug(s) Affected By Zinc finger protein PLAGL1 (PLAGL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Riboflavin DM8YMWE Acne vulgaris ED80 Approved [367]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [368]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [369]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Melanoma-associated antigen D2 (MAGED2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [129]
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Drug(s) Affected By Potassium channel subfamily K member 6 (KCNK6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [370]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [112]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [29]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [364]
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Drug(s) Affected By Pleckstrin homology domain-containing family A member 6 (PLEKHA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanine deaminase (GDA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [371]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [87]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oligoribonuclease, mitochondrial (REXO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
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Drug(s) Affected By Ankyrin repeat and SOCS box protein 1 (ASB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Selenium DM25CGV N. A. N. A. Approved [11]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [11]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [359]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [86]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sulfide:quinone oxidoreductase, mitochondrial (SQOR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Baculoviral IAP repeat-containing protein 5 (BIRC5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [372]
Gefitinib DM15F0X Colon adenocarcinoma Approved [373]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [374]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [44]
Etretinate DM2CZFA Keratosis ED56 Approved [375]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [376]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [377]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [378]
Quercetin DM3NC4M Obesity 5B81 Approved [379]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [380]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA-binding protein Musashi homolog 1 (MSI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [381]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [382]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [76]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [383]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [384]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adhesion G protein-coupled receptor B3 (ADGRB3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [175]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [385]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [122]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
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Drug(s) Affected By Frizzled-6 (FZD6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [321]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [75]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [75]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Low-density lipoprotein receptor-related protein 6 (LRP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [386]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [190]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [200]
Ethanol DMDRQZU Chronic pain MG30 Approved [387]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B2 (CCNB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [372]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [350]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [388]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [389]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [390]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTP-binding protein Di-Ras3 (DIRAS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ethanol DMDRQZU Chronic pain MG30 Approved [391]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [182]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [392]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [176]
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Drug(s) Affected By TBC1 domain family member 8 (TBC1D8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Zinc finger protein SNAI1 (SNAI1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [226]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [393]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [394]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [395]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [396]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Aldosterone DM9S2JW Hypertension BA00-BA04 Approved [397]
Sanguinarine DMDINFS Dental plaque DA08.4 Approved [398]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-E2 (CCNE2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [372]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [323]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [399]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [400]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [401]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [155]
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Drug(s) Affected By Epidermal growth factor receptor (EGFR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
BIBW 2992 DMTKD7Q Non-small-cell lung cancer 2C25.Y Approved [402]
Gefitinib DM15F0X Colon adenocarcinoma Approved [403]
Erlotinib DMCMBHA Adrenal gland neoplasm Approved [404]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [405]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [406]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [407]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [286]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Selenium DM25CGV N. A. N. A. Approved [408]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [409]
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Drug(s) Affected By Urokinase-type plasminogen activator (PLAU)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [317]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [410]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [317]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [411]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [412]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [413]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [286]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [414]
Gefitinib DM15F0X Colon adenocarcinoma Approved [269]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [220]
Selenium DM25CGV N. A. N. A. Approved [415]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [416]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [417]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [418]
Methotrexate DM2TEOL Anterior urethra cancer Approved [281]
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Drug(s) Affected By Osteocalcin (BGLAP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [419]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [420]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [248]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [421]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [422]
Pamidronate DMB4AVP Bone Paget disease Approved [423]
Falecalcitrol DMBI9ZJ Hyperparathyroidism 5A51 Approved [424]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [425]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [339]
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Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [426]
Methotrexate DM2TEOL Anterior urethra cancer Approved [281]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [265]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [427]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [428]
Paclitaxel DMLB81S Breast carcinoma Approved [429]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [430]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [42]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [431]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [432]
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Drug(s) Affected By Alkaline phosphatase, placental type (ALPP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lidocaine DML4ZOT Anaesthesia 9A78.6 Approved [21]
Paricalcitol DMYBV3G Hyperparathyroidism 5A51 Approved [21]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [433]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [434]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Isoproterenol DMK7MEY Atrioventricular block Approved [435]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [168]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [436]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA excision repair protein ERCC-1 (ERCC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [29]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [437]
Pemetrexed DMMX2E6 Central nervous system lymphoma 2B33.5 Approved [438]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [74]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [439]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent translocase ABCB1 (ABCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [440]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [441]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [442]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [443]
Cepharanthine DM9Y5JB N. A. N. A. Approved [444]
Itraconazole DMCR1MV Aspergillosis 1F20 Approved [445]
Clozapine DMFC71L Schizophrenia 6A20 Approved [446]
Midostaurin DMI6E0R Acute myeloid leukaemia 2A60 Approved [447]
Trifluoperazine DMKBYWI Anxiety Approved [448]
Olanzapine DMPFN6Y Bipolar depression Approved [446]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Amino acid transporter heavy chain SLC3A2 (SLC3A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [376]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [449]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [351]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [351]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [155]
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Drug(s) Affected By Matrilysin (MMP7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [450]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [222]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [347]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [451]
Clozapine DMFC71L Schizophrenia 6A20 Approved [452]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [453]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2A type 1 (H2AC11)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [401]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [454]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [54]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bone morphogenetic protein 4 (BMP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [226]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [455]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [456]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [393]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [457]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [458]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [459]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [460]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [461]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tissue factor (F3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [462]
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [463]
Methotrexate DM2TEOL Anterior urethra cancer Approved [464]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [465]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [466]
Quercetin DM3NC4M Obesity 5B81 Approved [467]
Fructose DM43AN2 Vomiting MD90 Approved [468]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [469]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [463]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [119]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Beta-galactosidase (GLB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [470]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [471]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [472]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Bendamustine hydrochloride DMFH15Z leukaemia 2A60-2B33 Approved [473]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.2 (H1-2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine-rich secretory protein 2 (CRISP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [474]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [475]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
Calphostin C DM9X2D0 N. A. N. A. Terminated [476]
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Drug(s) Affected By Cyclic AMP-dependent transcription factor ATF-4 (ATF4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [286]
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [477]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Selenium DM25CGV N. A. N. A. Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [376]
Pyrazinamide DM4IF32 Meningeal tuberculosis Approved [478]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [41]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [479]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [480]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [481]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [482]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [483]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [414]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [484]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [485]
Methotrexate DM2TEOL Anterior urethra cancer Approved [350]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [486]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [487]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [488]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [489]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [26]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [490]
Gefitinib DM15F0X Colon adenocarcinoma Approved [403]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [491]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [492]
Selenium DM25CGV N. A. N. A. Approved [11]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [416]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [493]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tenascin (TNC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [245]
Methotrexate DM2TEOL Anterior urethra cancer Approved [281]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [213]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [213]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [494]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [293]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [30]
Capsaicin DMGMF6V Back pain ME84.Z Approved [495]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NF-kappa-B inhibitor alpha (NFKBIA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [21]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [496]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [161]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [162]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [497]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [498]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [499]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [500]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin beta-8 (ITGB8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [107]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [348]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [501]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [128]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [502]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Threonine--tRNA ligase 1, cytoplasmic (TARS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [503]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [358]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By M-phase inducer phosphatase 3 (CDC25C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [191]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [504]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [505]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane 4 L6 family member 1 (TM4SF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [122]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [119]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [506]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent serotonin transporter (SLC6A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Paroxetine DM5PVQE Anxiety disorder 6B00-6B0Z Approved [507]
Fluoxetine DM3PD2C Bipolar depression Approved [508]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [509]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [510]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [511]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Aripiprazole DM3NUMH Bipolar I disorder Approved [512]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [510]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM4 (MCM4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [486]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [506]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM5 (MCM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [513]
Selenium DM25CGV N. A. N. A. Approved [11]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [389]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM7 (MCM7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Selenium DM25CGV N. A. N. A. Approved [11]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [487]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Catenin beta-1 (CTNNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [514]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [212]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [515]
Quercetin DM3NC4M Obesity 5B81 Approved [516]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [517]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [518]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [519]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [520]
Testosterone DM7HUNW Hot flushes GA30 Approved [218]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [521]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nitric oxide synthase, inducible (NOS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Indomethacin DMSC4A7 Bursitis Approved [522]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [523]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [524]
Methotrexate DM2TEOL Anterior urethra cancer Approved [46]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [525]
Quercetin DM3NC4M Obesity 5B81 Approved [526]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [49]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [527]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [334]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostaglandin G/H synthase 2 (PTGS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eicosapentaenoic acid/docosa-hexaenoic acid DMMUCG4 Hypertriglyceridemia 5C80.1 Approved [528]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [529]
Gamolenic acid DMQN30Z Allergy 4A80-4A85 Approved [530]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [247]
Flupentixol DM0DJ9O Schizophrenia 6A20 Approved [531]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [532]
Ibandronate DM0QZBN Hypercalcaemia 5B91.0 Approved [533]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [226]
Fexofenadine DM17ONX Allergic rhinitis CA08.0 Approved [534]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [535]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [400]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [536]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [287]
Gefitinib DM15F0X Colon adenocarcinoma Approved [373]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [491]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Etretinate DM2CZFA Keratosis ED56 Approved [375]
Prednisone DM2HG4X Acute asthma CA23 Approved [262]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [537]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [323]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase mTOR (MTOR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [538]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [539]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [540]
Gefitinib DM15F0X Colon adenocarcinoma Approved [541]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [542]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [416]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [510]
Quercetin DM3NC4M Obesity 5B81 Approved [543]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [140]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [544]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1B (CDKN1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [545]
Gefitinib DM15F0X Colon adenocarcinoma Approved [403]
Prednisone DM2HG4X Acute asthma CA23 Approved [262]
Methotrexate DM2TEOL Anterior urethra cancer Approved [546]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [547]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [405]
Quercetin DM3NC4M Obesity 5B81 Approved [548]
Fluoxetine DM3PD2C Bipolar depression Approved [549]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [550]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [551]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Retinaldehyde dehydrogenase 3 (ALDH1A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [21]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [552]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol transfer protein beta isoform (PITPNB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Clozapine DMFC71L Schizophrenia 6A20 Approved [503]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [553]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein F (CENPF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Methotrexate DM2TEOL Anterior urethra cancer Approved [350]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [554]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM2 (MCM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [294]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [71]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [193]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein kinase CLK2 (CLK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [334]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [283]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [555]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [57]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [92]
T83193 DMHO29Y Discovery agent N.A. Patented [556]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [557]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Regulator of G-protein signaling 4 (RGS4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [281]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [313]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [124]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [313]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1C (CDKN1C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Selenium DM25CGV N. A. N. A. Approved [11]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [486]
Quercetin DM3NC4M Obesity 5B81 Approved [69]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [152]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [152]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/myo-inositol cotransporter (SLC5A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [10]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [449]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ethanol DMDRQZU Chronic pain MG30 Approved [391]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcipressin-1 (RCAN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [558]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [559]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [104]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [558]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GTP-binding protein RAD (RRAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [154]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Testosterone enanthate DMB6871 N. A. N. A. Approved [78]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [52]
Ethanol DMDRQZU Chronic pain MG30 Approved [560]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP synthase subunit e, mitochondrial (ATP5ME)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [68]
Selenium DM25CGV N. A. N. A. Approved [11]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [561]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [303]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Indomethacin DMSC4A7 Bursitis Approved [562]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [563]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho-related GTP-binding protein RhoE (RND3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Selenium DM25CGV N. A. N. A. Approved [11]
Methotrexate DM2TEOL Anterior urethra cancer Approved [350]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [77]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [564]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ADP-ribosylation factor 6 (ARF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Propranolol DM79NTF Angina pectoris BA40 Approved [565]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [332]
Bortezomib DMNO38U Leukemia Approved [80]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [566]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [121]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H4 (H4C1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [22]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [190]
Selenium DM25CGV N. A. N. A. Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [376]
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Panobinostat DM58WKG Chronic graft versus host disease Approved [567]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcineurin subunit B type 1 (PPP3R1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [54]
Bortezomib DMNO38U Leukemia Approved [80]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [348]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [21]
Sirolimus DMGW1ID Advanced cancer 2A00-2F9Z Approved [21]
Cimetidine DMH61ZB Acid-reflux disorder DA22 Approved [21]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 4-aminobutyrate aminotransferase, mitochondrial (ABAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [246]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [168]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By POU domain, class 5, transcription factor 1 (POU5F1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [568]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [569]
Testosterone DM7HUNW Hot flushes GA30 Approved [570]
Lamotrigine DM8SXYG Bipolar disorder 6A60 Approved [571]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [572]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein inhibitor ID-3 (ID3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [159]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [206]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [454]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [323]
Methotrexate DM2TEOL Anterior urethra cancer Approved [281]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [264]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [313]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [26]
Selenium DM25CGV N. A. N. A. Approved [11]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [573]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [574]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [500]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [575]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [576]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glutamate receptor ionotropic, NMDA 1 (GRIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [510]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [510]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [577]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [510]
Testosterone DM7HUNW Hot flushes GA30 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Hydroxyurea DMOQVU9 Chronic myelogenous leukaemia 2A20.0 Approved [510]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [578]
Arsenic DMTL2Y1 N. A. N. A. Approved [579]
Sulfadiazine DMTW3R8 Rheumatic fever 1B40-1B42 Approved [510]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Induced myeloid leukemia cell differentiation protein Mcl-1 (MCL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [25]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [151]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [113]
Methotrexate DM2TEOL Anterior urethra cancer Approved [580]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [581]
Quercetin DM3NC4M Obesity 5B81 Approved [516]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [527]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [151]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [582]
Ethacrynic acid DM60QMR Edema MG29 Approved [583]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phorbol-12-myristate-13-acetate-induced protein 1 (PMAIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [158]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [513]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [44]
Methotrexate DM2TEOL Anterior urethra cancer Approved [584]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [585]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [586]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [527]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [308]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [191]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium channel protein type 5 subunit alpha (SCN5A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Disopyramide DM5SYZP Long QT syndrome BC65.0 Approved [21]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [587]
Flecainide DMSQDLE Tachyarrhythmias BC71 Approved [588]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [589]
Meloxicam DM2AR7L Arthritis FA20 Approved [590]
Quercetin DM3NC4M Obesity 5B81 Approved [591]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [592]
Nefazodone DM4ZS8M Major depressive disorder 6A70.3 Approved [593]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [55]
Retigabine DMGNYIH Behcet disease 4A62 Approved [594]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA replication licensing factor MCM6 (MCM6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Methotrexate DM2TEOL Anterior urethra cancer Approved [350]
Quercetin DM3NC4M Obesity 5B81 Approved [38]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [595]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [596]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [206]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Fluoxetine DM3PD2C Bipolar depression Approved [351]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Estrone DM5T6US Acne vulgaris ED80 Approved [206]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [155]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [155]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho GTPase-activating protein 29 (ARHGAP29)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [486]
Quercetin DM3NC4M Obesity 5B81 Approved [92]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [213]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Folic Acid DMEMBJC Colorectal carcinoma Approved [597]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein Largen (PRR16)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [153]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Folic Acid DMEMBJC Colorectal carcinoma Approved [597]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [598]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase RNF144B (RNF144B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [213]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [178]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [85]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [105]
Indomethacin DMSC4A7 Bursitis Approved [562]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium-dependent phosphate transporter 1 (SLC20A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Phosphate DMUXQG7 Constipation DD91.1 Approved [599]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [118]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [449]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [600]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [73]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein naked cuticle homolog 1 (NKD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [513]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [601]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [513]
Arsenic DMTL2Y1 N. A. N. A. Approved [602]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By PDZ and LIM domain protein 5 (PDLIM5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [10]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Haloperidol DM96SE0 Delirium Approved [503]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Folic Acid DMEMBJC Colorectal carcinoma Approved [31]
Benzatropine DMF7EXL Parkinsonian disorder Approved [503]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Secreted frizzled-related protein 2 (SFRP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [195]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [603]
Arsenic DMTL2Y1 N. A. N. A. Approved [106]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [604]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cell division control protein 6 homolog (CDC6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [261]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [323]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [486]
Quercetin DM3NC4M Obesity 5B81 Approved [114]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [70]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [76]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [605]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2B type 1-L (H2BC13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [98]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [348]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
Berberine DMC5Q8X N. A. N. A. Phase 4 [606]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [364]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [360]
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Drug(s) Affected By Homeobox protein NANOG (NANOG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [607]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [208]
Quercetin DM3NC4M Obesity 5B81 Approved [568]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [241]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [211]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [569]
Testosterone DM7HUNW Hot flushes GA30 Approved [570]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [608]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Popeye domain-containing protein 3 (POPDC3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [72]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [88]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [55]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [609]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
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Drug(s) Affected By Large ribosomal subunit protein uL29m (MRPL47)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [610]
Urethane DM7NSI0 N. A. N. A. Phase 4 [56]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [360]
Milchsaure DM462BT Pruritus EC90 Investigative [611]
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Drug(s) Affected By Frizzled-3 (FZD3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [62]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [612]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [613]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cysteine and histidine-rich domain-containing protein 1 (CHORDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [11]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Haloperidol DM96SE0 Delirium Approved [503]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [79]
Clozapine DMFC71L Schizophrenia 6A20 Approved [503]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related protein Rab-23 (RAB23)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [454]
Testosterone DM7HUNW Hot flushes GA30 Approved [136]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [83]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [137]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [80]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [104]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [126]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Frizzled-4 (FZD4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [139]
Leflunomide DMR8ONJ Arthritis FA20 Approved [103]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [321]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [86]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By SH3 and multiple ankyrin repeat domains protein 2 (SHANK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Selenium DM25CGV N. A. N. A. Approved [11]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [510]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [510]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [50]
Gabapentin DM6T924 Complex partial seizure 8A68.0 Approved [510]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [331]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Axin-2 (AXIN2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Panobinostat DM58WKG Chronic graft versus host disease Approved [29]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [140]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [84]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [321]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [601]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [53]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [614]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [81]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [406]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepatoma-derived growth factor-related protein 3 (HDGFL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [102]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [72]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [346]
Methotrexate DM2TEOL Anterior urethra cancer Approved [170]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [615]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [200]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [364]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [360]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [58]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (PIK3CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [205]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [82]
Quercetin DM3NC4M Obesity 5B81 Approved [101]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [40]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [135]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [616]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [117]
Cantharidin DMBP5N3 Molluscum contagiosum infection 1E76 Approved [617]
Atorvastatin DMF28YC Acute coronary syndrome BA41 Approved [618]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [51]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
Glycogen synthase kinase-3 alpha (GSK-3A) TTRZQE3 GSK3A_HUMAN Inhibitor [1]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
3',5'-cyclic-AMP phosphodiesterase 4B (PDE4B) OTOA8WU2 PDE4B_HUMAN Gene/Protein Processing [2]
4-aminobutyrate aminotransferase, mitochondrial (ABAT) OTXAGR7J GABT_HUMAN Gene/Protein Processing [3]
5-hydroxytryptamine receptor 2A (HTR2A) OTWXJX0M 5HT2A_HUMAN Gene/Protein Processing [2]
Abl interactor 2 (ABI2) OT8GIIS5 ABI2_HUMAN Gene/Protein Processing [2]
Acetylcholinesterase (ACHE) OT2H8HG6 ACES_HUMAN Protein Interaction/Cellular Processes [4]
Acylamino-acid-releasing enzyme (APEH) OTX258QE ACPH_HUMAN Gene/Protein Processing [2]
Adenomatous polyposis coli protein 2 (APC2) OTRH91CX APCL_HUMAN Gene/Protein Processing [2]
Adhesion G protein-coupled receptor B3 (ADGRB3) OT1EWGRW AGRB3_HUMAN Gene/Protein Processing [3]
Adhesion G protein-coupled receptor E5 (ADGRE5) OTTSB84Q AGRE5_HUMAN Gene/Protein Processing [2]
ADP-ribosylation factor 6 (ARF6) OTVV7KJO ARF6_HUMAN Gene/Protein Processing [3]

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48 Simvastatin induces apoptosis in human colon cancer cells and in tumor xenografts, and attenuates colitis-associated colon cancer in mice. Int J Cancer. 2008 Aug 15;123(4):951-7. doi: 10.1002/ijc.23593.
49 Increased sensitivity for troglitazone-induced cytotoxicity using a human in vitro co-culture model. Toxicol In Vitro. 2009 Oct;23(7):1387-95.
50 Development of a neural teratogenicity test based on human embryonic stem cells: response to retinoic acid exposure. Toxicol Sci. 2011 Dec;124(2):370-7.
51 Integrative omics data analyses of repeated dose toxicity of valproic acid in vitro reveal new mechanisms of steatosis induction. Toxicology. 2018 Jan 15;393:160-170.
52 Characterization of formaldehyde's genotoxic mode of action by gene expression analysis in TK6 cells. Arch Toxicol. 2013 Nov;87(11):1999-2012.
53 Temozolomide induces activation of Wnt/-catenin signaling in glioma cells via PI3K/Akt pathway: implications in glioma therapy. Cell Biol Toxicol. 2020 Jun;36(3):273-278. doi: 10.1007/s10565-019-09502-7. Epub 2019 Nov 22.
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55 Gene Expression Regulation and Pathway Analysis After Valproic Acid and Carbamazepine Exposure in a Human Embryonic Stem Cell-Based Neurodevelopmental Toxicity Assay. Toxicol Sci. 2015 Aug;146(2):311-20. doi: 10.1093/toxsci/kfv094. Epub 2015 May 15.
56 Ethyl carbamate induces cell death through its effects on multiple metabolic pathways. Chem Biol Interact. 2017 Nov 1;277:21-32.
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