Details of the Drug Combination

General Information of Drug Combination (ID: DCFCPVE)

Drug Combination Name
Amiodarone Acetylcysteine
Indication
Disease Entry Status REF
Thoracic Surgery Phase 3 [1]
Component Drugs Amiodarone   DMUTEX3 Acetylcysteine   DMWSXI4
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Amiodarone
Disease Entry ICD 11 Status REF
Tachyarrhythmias BC71 Approved [2]
Ventricular tachycardia BC71 Approved [3]
Coronavirus Disease 2019 (COVID-19) 1D6Y Phase 2/3 [4]
Amiodarone Interacts with 2 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Potassium channel unspecific (KC) TT1VOHK NOUNIPROTAC Modulator [13]
HUMAN two pore channel subtype 2 (TPC2) TTHQJ2Y TPC2_HUMAN Blocker [14]
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Amiodarone Interacts with 1 DTP Molecule(s)
DTP Name DTP ID UniProt ID Mode of Action REF
P-glycoprotein 1 (ABCB1) DTUGYRD MDR1_HUMAN Substrate [15]
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Amiodarone Interacts with 7 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [16]
Cytochrome P450 1A2 (CYP1A2) DEJGDUW CP1A2_HUMAN Metabolism [17]
Cytochrome P450 1A1 (CYP1A1) DE6OQ3W CP1A1_HUMAN Metabolism [18]
Cytochrome P450 2D6 (CYP2D6) DECB0K3 CP2D6_HUMAN Metabolism [19]
Cytochrome P450 2C8 (CYP2C8) DES5XRU CP2C8_HUMAN Metabolism [20]
Cytochrome P450 2C9 (CYP2C9) DE5IED8 CP2C9_HUMAN Metabolism [21]
Mephenytoin 4-hydroxylase (CYP2C19) DEGTFWK CP2CJ_HUMAN Metabolism [18]
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⏷ Show the Full List of 7 DME(s)
Amiodarone Interacts with 627 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) OTQGYY83 CP3A4_HUMAN Decreases Activity [22]
Cytochrome P450 2D6 (CYP2D6) OTZJC802 CP2D6_HUMAN Increases Expression [8]
Cytochrome P450 2C9 (CYP2C9) OTGLBN29 CP2C9_HUMAN Increases Expression [23]
Potassium voltage-gated channel subfamily H member 2 (KCNH2) OTZX881H KCNH2_HUMAN Decreases Activity [24]
Sodium channel protein type 5 subunit alpha (SCN5A) OTGYZWR6 SCN5A_HUMAN Affects Response To Substance [25]
Tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) OTA1CPBV TR10B_HUMAN Increases Expression [26]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Decreases Activity [27]
Cytochrome P450 2C8 (CYP2C8) OTHCWT42 CP2C8_HUMAN Decreases Activity [22]
Nuclear protein 1 (NUPR1) OT4FU8C0 NUPR1_HUMAN Increases Expression [7]
Serine protease hepsin (HPN) OT7QNA61 HEPS_HUMAN Increases Expression [7]
Fatty acid-binding protein, liver (FABP1) OTR34ETM FABPL_HUMAN Increases Expression [7]
Solute carrier family 2, facilitated glucose transporter member 3 (SLC2A3) OT2HZK5M GTR3_HUMAN Decreases Expression [7]
Lanosterol synthase (LSS) OT9W2SFH LSS_HUMAN Increases Expression [7]
Inhibin beta E chain (INHBE) OTOI2NYG INHBE_HUMAN Increases Expression [7]
Acid ceramidase (ASAH1) OT1DNGXL ASAH1_HUMAN Increases Expression [7]
Cytochrome P450 1A2 (CYP1A2) OTLLBX48 CP1A2_HUMAN Decreases Activity [28]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Increases Expression [29]
AP-1 complex subunit sigma-1A (AP1S1) OTQ2H8DN AP1S1_HUMAN Decreases Expression [29]
Transgelin (TAGLN) OTAEZ0KP TAGL_HUMAN Decreases Expression [29]
Lysophospholipase D GDPD3 (GDPD3) OTOHM9QM GDPD3_HUMAN Increases Expression [29]
Fibronectin type III domain-containing protein 4 (FNDC4) OTOQK0WK FNDC4_HUMAN Increases Expression [29]
Protein DEPP1 (DEPP1) OTB36PHJ DEPP1_HUMAN Increases Expression [29]
PLAC8-like protein 1 (PLAC8L1) OTHF4LKX PL8L1_HUMAN Increases Expression [8]
ADP-ribose glycohydrolase MACROD2 (MACROD2) OTNQCHC6 MACD2_HUMAN Increases Expression [8]
FERM domain-containing protein 3 (FRMD3) OT0CD2GG FRMD3_HUMAN Increases Expression [8]
EF-hand calcium-binding domain-containing protein 5 (EFCAB5) OTKVCIP6 EFCB5_HUMAN Increases Expression [8]
Olfactory receptor 14I1 (OR14I1) OTYOYAMT O14I1_HUMAN Increases Expression [8]
Proline-rich protein 19 (PRR19) OTWBR3LB PRR19_HUMAN Increases Expression [8]
ERI1 exoribonuclease 2 (ERI2) OTBVAFYC ERI2_HUMAN Increases Expression [8]
PHD finger protein 20-like protein 1 (PHF20L1) OTCLYOCL P20L1_HUMAN Increases Expression [8]
ATP-dependent RNA helicase DDX39A (DDX39A) OT0Z6E1K DX39A_HUMAN Increases Expression [8]
Phospholemman (FXYD1) OTNKT6GP PLM_HUMAN Increases Expression [8]
Activator of apoptosis harakiri (HRK) OTR4GWJ0 HRK_HUMAN Increases Expression [8]
26S proteasome non-ATPase regulatory subunit 11 (PSMD11) OT8KO67V PSD11_HUMAN Increases Expression [8]
Class E basic helix-loop-helix protein 40 (BHLHE40) OTITX14U BHE40_HUMAN Increases Expression [8]
Suppressor of cytokine signaling 6 (SOCS6) OT2O5ZBK SOCS6_HUMAN Increases Expression [8]
Acyl-coenzyme A thioesterase 8 (ACOT8) OTHY684G ACOT8_HUMAN Increases Expression [8]
Free fatty acid receptor 3 (FFAR3) OTSAF60T FFAR3_HUMAN Increases Expression [8]
Protein lin-7 homolog A (LIN7A) OTFL3PUX LIN7A_HUMAN Increases Expression [8]
NEDD4-binding protein 3 (N4BP3) OTZW1RQS N4BP3_HUMAN Increases Expression [8]
Fanconi anemia group A protein (FANCA) OTPEFJD4 FANCA_HUMAN Increases Expression [8]
Transcription factor MafG (MAFG) OTBQFUZH MAFG_HUMAN Increases Expression [8]
Period circadian protein homolog 1 (PER1) OTVQF3WX PER1_HUMAN Increases Expression [8]
Cytochrome P450 26A1 (CYP26A1) OTL1DFWV CP26A_HUMAN Increases Expression [8]
Interleukin-1 receptor-associated kinase-like 2 (IRAK2) OT6Y1QZN IRAK2_HUMAN Increases Expression [8]
Rho guanine nucleotide exchange factor 9 (ARHGEF9) OTB1FLIW ARHG9_HUMAN Increases Expression [8]
Krueppel-like factor 4 (KLF4) OT4O9RQW KLF4_HUMAN Increases Expression [8]
Bcl-2-like protein 11 (BCL2L11) OTNQQWFJ B2L11_HUMAN Increases Expression [8]
Maleylacetoacetate isomerase (GSTZ1) OTQ43JCE MAAI_HUMAN Increases Expression [8]
Protocadherin-7 (PCDH7) OTP091X8 PCDH7_HUMAN Increases Expression [8]
Signal-induced proliferation-associated 1-like protein 3 (SIPA1L3) OTNYFUM3 SI1L3_HUMAN Increases Expression [8]
Cyclin-T1 (CCNT1) OTDYVGCP CCNT1_HUMAN Increases Expression [8]
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 (HCN1) OTVOWKQ7 HCN1_HUMAN Increases Expression [8]
SH2 domain-containing protein 1A (SH2D1A) OTLU49I5 SH21A_HUMAN Increases Expression [8]
Oligophrenin-1 (OPHN1) OTDURZAV OPHN1_HUMAN Increases Expression [8]
Checkpoint protein HUS1 (HUS1) OTY1XON9 HUS1_HUMAN Increases Expression [8]
Microphthalmia-associated transcription factor (MITF) OT6XJCZH MITF_HUMAN Increases Expression [8]
Carboxyl-terminal PDZ ligand of neuronal nitric oxide synthase protein (NOS1AP) OTDFOBRU CAPON_HUMAN Increases Expression [8]
Transmembrane and coiled-coil domains protein 2 (TMCC2) OT0D7IYD TMCC2_HUMAN Increases Expression [8]
Calcium-responsive transactivator (SS18L1) OT9ZEGV7 CREST_HUMAN Increases Expression [8]
Low-density lipoprotein receptor-related protein 5 (LRP5) OTCC4JPH LRP5_HUMAN Increases Expression [8]
PC4 and SFRS1-interacting protein (PSIP1) OT4YAFUS PSIP1_HUMAN Increases Expression [8]
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5L (TAF5L) OTCP6ZYD TAF5L_HUMAN Increases Expression [8]
Polycomb protein EED (EED) OTJFHCDF EED_HUMAN Increases Expression [8]
Syntaxin-11 (STX11) OTHFRSFP STX11_HUMAN Increases Expression [8]
Death effector domain-containing protein (DEDD) OTIL349E DEDD_HUMAN Increases Expression [8]
TOM1-like protein 1 (TOM1L1) OT37NXR0 TM1L1_HUMAN Increases Expression [8]
Protein phosphatase 1B (PPM1B) OTZMH6V3 PPM1B_HUMAN Increases Expression [8]
Serine/threonine-protein kinase 16 (STK16) OTUOY83H STK16_HUMAN Increases Expression [8]
Protein phosphatase 1 regulatory subunit 15A (PPP1R15A) OTYG179K PR15A_HUMAN Increases Expression [8]
Gamma-butyrobetaine dioxygenase (BBOX1) OTKEX4RK BODG_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase RNF8 (RNF8) OTRR43PZ RNF8_HUMAN Increases Expression [8]
Cystatin-F (CST7) OTQWZUVQ CYTF_HUMAN Increases Expression [8]
Dolichol phosphate-mannose biosynthesis regulatory protein (DPM2) OTDERBWM DPM2_HUMAN Increases Expression [8]
FERM, ARHGEF and pleckstrin domain-containing protein 2 (FARP2) OTNRQIMK FARP2_HUMAN Increases Expression [8]
SLIT and NTRK-like protein 3 (SLITRK3) OT018P93 SLIK3_HUMAN Increases Expression [8]
Protein HEXIM1 (HEXIM1) OTBK7278 HEXI1_HUMAN Increases Expression [8]
Semaphorin-3D (SEMA3D) OTD5TJV1 SEM3D_HUMAN Increases Expression [8]
Elongator complex protein 1 (ELP1) OTYEWBF7 ELP1_HUMAN Increases Expression [8]
Protocadherin-8 (PCDH8) OTDDOQM2 PCDH8_HUMAN Increases Expression [8]
Growth arrest and DNA damage-inducible protein GADD45 gamma (GADD45G) OT8V1J4M GA45G_HUMAN Increases Expression [8]
Supervillin (SVIL) OTWQQ1WK SVIL_HUMAN Increases Expression [8]
Neuroendocrine secretory protein 55 (GNAS) OTMH8BKJ GNAS3_HUMAN Increases Expression [8]
Neuronal pentraxin receptor (NPTXR) OTQJEOIH NPTXR_HUMAN Increases Expression [8]
T-cell leukemia/lymphoma protein 1B (TCL1B) OT4CSO39 TCL1B_HUMAN Increases Expression [8]
Tyrosine-protein kinase ABL1 (ABL1) OT09YVXH ABL1_HUMAN Increases Expression [8]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Increases Expression [8]
Proenkephalin-B (PDYN) OTEJ6430 PDYN_HUMAN Increases Expression [8]
Interleukin-1 alpha (IL1A) OTPSGILV IL1A_HUMAN Increases Expression [8]
Albumin (ALB) OTVMM513 ALBU_HUMAN Increases Expression [8]
Semenogelin-1 (SEMG1) OT6Z4BPQ SEMG1_HUMAN Increases Expression [8]
HLA class II histocompatibility antigen, DP beta 1 chain (HLA-DPB1) OTW8JHU2 DPB1_HUMAN Increases Expression [8]
Metallothionein-1F (MT1F) OTZVUYG1 MT1F_HUMAN Increases Expression [8]
Intercellular adhesion molecule 1 (ICAM1) OTTOIX77 ICAM1_HUMAN Increases Expression [8]
Phosphoglycerate kinase 2 (PGK2) OTMD662Q PGK2_HUMAN Increases Expression [8]
Acylphosphatase-1 (ACYP1) OTR77NZD ACYP1_HUMAN Increases Expression [8]
Amino acid transporter heavy chain SLC3A2 (SLC3A2) OTBR33M9 4F2_HUMAN Increases Expression [8]
Nuclear factor 1 C-type (NFIC) OTLMCUIB NFIC_HUMAN Increases Expression [8]
Alpha-2A adrenergic receptor (ADRA2A) OTZFGOTP ADA2A_HUMAN Increases Expression [8]
Homeobox protein Hox-C4 (HOXC4) OT52VJ6V HXC4_HUMAN Increases Expression [8]
Annexin A4 (ANXA4) OTUCRYXL ANXA4_HUMAN Increases Expression [8]
2',3'-cyclic-nucleotide 3'-phosphodiesterase (CNP) OTB8HCED CN37_HUMAN Increases Expression [8]
Histone H2A type 1 (H2AC11) OTN9P0BO H2A1_HUMAN Increases Expression [8]
Oncomodulin-1 (OCM) OTQRML29 ONCO_HUMAN Increases Expression [8]
LIM and senescent cell antigen-like-containing domain protein 3 (LIMS3) OTTMS7V8 LIMS3_HUMAN Increases Expression [8]
Sulfotransferase 1A3 (SULT1A4) OTHJ8WWV ST1A3_HUMAN Increases Expression [8]
Adenosine receptor A3 (ADORA3) OTHO1BLK AA3R_HUMAN Increases Expression [8]
Receptor-type tyrosine-protein phosphatase F (PTPRF) OTH5KF2D PTPRF_HUMAN Increases Expression [8]
Microsomal glutathione S-transferase 1 (MGST1) OTGN1KVZ MGST1_HUMAN Increases Expression [8]
Chromogranin-A (CHGA) OTXYX5JH CMGA_HUMAN Increases Expression [8]
Thyroid hormone receptor beta (THRB) OTBBIRHZ THB_HUMAN Increases Expression [8]
Proto-oncogene DBL (MCF2) OTB9N93T MCF2_HUMAN Increases Expression [8]
Interferon regulatory factor 1 (IRF1) OT43DI6J IRF1_HUMAN Increases Expression [8]
E3 SUMO-protein ligase EGR2 (EGR2) OTAVQ78J EGR2_HUMAN Increases Expression [8]
Glucose-6-phosphate 1-dehydrogenase (G6PD) OT300SMK G6PD_HUMAN Increases Expression [8]
Collagen alpha-1(XI) chain (COL11A1) OTB0DRMS COBA1_HUMAN Increases Expression [8]
Myosin light chain 4 (MYL4) OTURFCSE MYL4_HUMAN Increases Expression [8]
5-aminolevulinate synthase, non-specific, mitochondrial (ALAS1) OTQY6ZSF HEM1_HUMAN Increases Expression [8]
Metallothionein-1G (MT1G) OTAV1OCR MT1G_HUMAN Increases Expression [8]
Troponin T, slow skeletal muscle (TNNT1) OT8PBOAR TNNT1_HUMAN Increases Expression [8]
Leukemia inhibitory factor (LIF) OTO46S5S LIF_HUMAN Increases Expression [8]
Cytotoxic T-lymphocyte protein 4 (CTLA4) OTYQR611 CTLA4_HUMAN Increases Expression [8]
Homeobox protein Hox-B6 (HOXB6) OT3TFQ0U HXB6_HUMAN Increases Expression [8]
CCAAT/enhancer-binding protein beta (CEBPB) OTM9MQIA CEBPB_HUMAN Increases Expression [8]
Early growth response protein 1 (EGR1) OTCP6XGZ EGR1_HUMAN Increases Expression [8]
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma (PDE6G) OTWA8TIQ CNRG_HUMAN Increases Expression [8]
Cyclic AMP-dependent transcription factor ATF-3 (ATF3) OTC1UOHP ATF3_HUMAN Increases Expression [8]
Inter-alpha-trypsin inhibitor heavy chain H2 (ITIH2) OTG3WBBE ITIH2_HUMAN Increases Expression [8]
Calpain-3 (CAPN3) OTCHG3YK CAN3_HUMAN Increases Expression [8]
Tumor necrosis factor alpha-induced protein 3 (TNFAIP3) OTVLI4DD TNAP3_HUMAN Increases Expression [8]
Kit ligand (KITLG) OTB9AVQ4 SCF_HUMAN Increases Expression [8]
Lutropin-choriogonadotropic hormone receptor (LHCGR) OTSVIJ6I LSHR_HUMAN Increases Expression [8]
Paired box protein Pax-3 (PAX3) OTN5PJZV PAX3_HUMAN Increases Expression [8]
Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A) OTDRV63V GA45A_HUMAN Increases Expression [8]
Deoxyribonuclease-1 (DNASE1) OTM4KWB3 DNAS1_HUMAN Increases Expression [8]
Collagen alpha-2(VIII) chain (COL8A2) OTASWJ69 CO8A2_HUMAN Increases Expression [8]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Increases Expression [8]
Tyrosine-protein phosphatase non-receptor type 3 (PTPN3) OTSLZBVY PTN3_HUMAN Increases Expression [8]
Dual specificity protein phosphatase 1 (DUSP1) OTN6BR75 DUS1_HUMAN Increases Expression [8]
M-phase inducer phosphatase 1 (CDC25A) OTSLKKCO MPIP1_HUMAN Increases Expression [8]
Guanylate-binding protein 2 (GBP2) OTVU4G07 GBP2_HUMAN Increases Expression [8]
Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial (DUT) OT0THBVA DUT_HUMAN Increases Expression [8]
Guanylate cyclase soluble subunit alpha-2 (GUCY1A2) OTR6DVAA GCYA2_HUMAN Increases Expression [8]
Mannose-6-phosphate isomerase (MPI) OTBH6ZK1 MPI_HUMAN Increases Expression [8]
Merlin (NF2) OT6E5ACG MERL_HUMAN Increases Expression [8]
Sepiapterin reductase (SPR) OT1ROA8B SPRE_HUMAN Increases Expression [8]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Increases Expression [8]
Basigin (BSG) OTD0CVEC BASI_HUMAN Increases Expression [8]
DNA damage-inducible transcript 3 protein (DDIT3) OTI8YKKE DDIT3_HUMAN Increases Expression [8]
Myosin-11 (MYH11) OTVNVWY3 MYH11_HUMAN Increases Expression [8]
Insulin-like growth factor-binding protein complex acid labile subunit (IGFALS) OTTWCZYM ALS_HUMAN Increases Expression [8]
Gap junction alpha-5 protein (GJA5) OTRMZVO6 CXA5_HUMAN Increases Expression [8]
Transcription factor 7 (TCF7) OT1ID822 TCF7_HUMAN Increases Expression [8]
Activin receptor type-1B (ACVR1B) OT778HIQ ACV1B_HUMAN Increases Expression [8]
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A (PIGA) OT51UWUR PIGA_HUMAN Increases Expression [8]
Growth/differentiation factor 5 (GDF5) OTOV8S81 GDF5_HUMAN Increases Expression [8]
Cell surface glycoprotein MUC18 (MCAM) OTT8XKGE MUC18_HUMAN Increases Expression [8]
Nuclear receptor subfamily 4 group A member 2 (NR4A2) OT3F9IR2 NR4A2_HUMAN Increases Expression [8]
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform (PHKA1) OTLPQCRF KPB1_HUMAN Increases Expression [8]
Lys-63-specific deubiquitinase BRCC36 (BRCC3) OTK0ZN7Y BRCC3_HUMAN Increases Expression [8]
Mannan-binding lectin serine protease 1 (MASP1) OTWWCNZP MASP1_HUMAN Increases Expression [8]
Tryptophan 2,3-dioxygenase (TDO2) OTV5HKJ4 T23O_HUMAN Increases Expression [8]
DNA primase large subunit (PRIM2) OTGT0KTF PRI2_HUMAN Increases Expression [8]
Regulator of G-protein signaling 6 (RGS6) OT48432Z RGS6_HUMAN Increases Expression [8]
Presenilin-1 (PSEN1) OTKL39RT PSN1_HUMAN Increases Expression [8]
Cytochrome P450 2J2 (CYP2J2) OTJBTEH8 CP2J2_HUMAN Increases Expression [8]
C-C chemokine receptor type 9 (CCR9) OT5FSOD8 CCR9_HUMAN Increases Expression [8]
H(+)/Cl(-) exchange transporter 5 (CLCN5) OT9YXZSO CLCN5_HUMAN Increases Expression [8]
H(+)/Cl(-) exchange transporter 6 (CLCN6) OT9QW5R4 CLCN6_HUMAN Increases Expression [8]
Transketolase-like protein 1 (TKTL1) OTPP3M35 TKTL1_HUMAN Increases Expression [8]
Protein FosB (FOSB) OTW6C05J FOSB_HUMAN Increases Expression [8]
Clathrin heavy chain 2 (CLTCL1) OT6W5BNR CLH2_HUMAN Increases Expression [8]
Sodium/myo-inositol cotransporter (SLC5A3) OT6FY2KA SC5A3_HUMAN Increases Expression [8]
Protein HIRA (HIRA) OTON40EJ HIRA_HUMAN Increases Expression [8]
Telomeric repeat-binding factor 1 (TERF1) OTIJCMGB TERF1_HUMAN Increases Expression [8]
Eukaryotic translation initiation factor 5 (EIF5) OT79PQUN IF5_HUMAN Increases Expression [8]
GTP-binding protein GEM (GEM) OT6SK8ZV GEM_HUMAN Increases Expression [8]
Peregrin (BRPF1) OTPC9GXB BRPF1_HUMAN Increases Expression [8]
Caspase-9 (CASP9) OTD4RFFG CASP9_HUMAN Increases Expression [8]
Cadherin-15 (CDH15) OTJ1TO02 CAD15_HUMAN Increases Expression [8]
Caveolin-3 (CAV3) OTWSFDB4 CAV3_HUMAN Increases Expression [8]
T-box transcription factor TBX4 (TBX4) OTW58FG4 TBX4_HUMAN Increases Expression [8]
Sestrin-2 (SESN2) OT889IXY SESN2_HUMAN Increases Expression [8]
Small integral membrane protein 11 (SMIM11) OTZPLVUC SIM11_HUMAN Increases Expression [8]
Actin-related protein 2/3 complex subunit 4 (ARPC4) OT0ZE01B ARPC4_HUMAN Increases Expression [8]
Ras-related C3 botulinum toxin substrate 3 (RAC3) OT2RE7A7 RAC3_HUMAN Increases Expression [8]
Lysozyme C (LYZ) OTD7H0G6 LYSC_HUMAN Increases Expression [8]
Histone H4 (H4C1) OTB71W46 H4_HUMAN Increases Expression [8]
Histone H2B type 1-C/E/F/G/I (H2BC10) OTLQH0D6 H2B1C_HUMAN Increases Expression [8]
Calcineurin subunit B type 1 (PPP3R1) OTGQNFJQ CANB1_HUMAN Increases Expression [8]
Inward rectifier potassium channel 2 (KCNJ2) OT2OQEZS KCNJ2_HUMAN Increases Expression [8]
Histone H3.1 (H3C1) OTGBGOZW H31_HUMAN Increases Expression [8]
Disks large homolog 4 (DLG4) OTD9E2LU DLG4_HUMAN Increases Expression [8]
UDP-galactose translocator (SLC35A2) OTQOTOWZ S35A2_HUMAN Increases Expression [8]
Metallothionein-1X (MT1X) OT9AKFVS MT1X_HUMAN Increases Expression [8]
Large ribosomal subunit protein eL42 (RPL36A) OT1LYV85 RL36A_HUMAN Increases Expression [8]
Rho GTPase-activating protein 4 (ARHGAP4) OTXV053R RHG04_HUMAN Increases Expression [8]
Cyclin-dependent kinase 17 (CDK17) OTO35W64 CDK17_HUMAN Increases Expression [8]
Spectrin beta chain, non-erythrocytic 1 (SPTBN1) OTOVM4D4 SPTB2_HUMAN Increases Expression [8]
Transcription factor RelB (RELB) OTU3QYEF RELB_HUMAN Increases Expression [8]
Guanylate cyclase soluble subunit beta-1 (GUCY1B1) OTSHPHVB GCYB1_HUMAN Increases Expression [8]
AT-rich interactive domain-containing protein 5A (ARID5A) OTQT7CG9 ARI5A_HUMAN Increases Expression [8]
Keratin, type I cytoskeletal 17 (KRT17) OT6Y1DPK K1C17_HUMAN Increases Expression [8]
Hepatocyte growth factor activator (HGFAC) OTKI6HM0 HGFA_HUMAN Increases Expression [8]
Max dimerization protein 1 (MXD1) OTS5CTHX MAD1_HUMAN Increases Expression [8]
Neuronal acetylcholine receptor subunit beta-3 (CHRNB3) OTE5XENW ACHB3_HUMAN Increases Expression [8]
Myocyte-specific enhancer factor 2C (MEF2C) OTZGF1Y5 MEF2C_HUMAN Increases Expression [8]
Sperm-associated antigen 1 (SPAG1) OT29JZKW SPAG1_HUMAN Increases Expression [8]
Protocadherin-1 (PCDH1) OT7KDEL3 PCDH1_HUMAN Increases Expression [8]
Schlafen family member 5 (SLFN5) OTT1AESL SLFN5_HUMAN Increases Expression [8]
Putative sodium-coupled neutral amino acid transporter 11 (SLC38A11) OTFXRU35 S38AB_HUMAN Increases Expression [8]
Neuroblast differentiation-associated protein AHNAK (AHNAK) OT6KH1WG AHNK_HUMAN Increases Expression [8]
Thyrotroph embryonic factor (TEF) OTY3LAD9 TEF_HUMAN Increases Expression [8]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1) OTNYXOZO KCMA1_HUMAN Increases Expression [8]
PR domain zinc finger protein 2 (PRDM2) OT8L7CGX PRDM2_HUMAN Increases Expression [8]
Acetyl-CoA carboxylase 1 (ACACA) OT5CQPZY ACACA_HUMAN Increases Expression [8]
Krueppel-like factor 10 (KLF10) OT4F4UGS KLF10_HUMAN Increases Expression [8]
Dehydrogenase/reductase SDR family member 2, mitochondrial (DHRS2) OTFHWIY8 DHRS2_HUMAN Increases Expression [8]
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform (PPP2R5C) OTF7CGO2 2A5G_HUMAN Increases Expression [8]
Sequestosome-1 (SQSTM1) OTGY5D5J SQSTM_HUMAN Increases Expression [8]
Interleukin-10 receptor subunit alpha (IL10RA) OTOX3D1D I10R1_HUMAN Increases Expression [8]
Rho guanine nucleotide exchange factor 7 (ARHGEF7) OT9BPJCL ARHG7_HUMAN Increases Expression [8]
Dynactin subunit 1 (DCTN1) OT5B51FJ DCTN1_HUMAN Increases Expression [8]
Metabotropic glutamate receptor 2 (GRM2) OTD88Q92 GRM2_HUMAN Increases Expression [8]
Hepatocyte nuclear factor 4-gamma (HNF4G) OTTSIHJP HNF4G_HUMAN Increases Expression [8]
Plastin-1 (PLS1) OTWURB8U PLSI_HUMAN Increases Expression [8]
DNA replication complex GINS protein PSF1 (GINS1) OTVQZMMQ PSF1_HUMAN Increases Expression [8]
Prostaglandin reductase 1 (PTGR1) OTMAR351 PTGR1_HUMAN Increases Expression [8]
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein (HERPUD1) OT9EROL6 HERP1_HUMAN Increases Expression [8]
Platelet-derived growth factor receptor-like protein (PDGFRL) OTJPRECT PGFRL_HUMAN Increases Expression [8]
Homeobox protein SIX1 (SIX1) OT70YYWM SIX1_HUMAN Increases Expression [8]
Cystatin-M (CST6) OTZVHJTF CYTM_HUMAN Increases Expression [8]
Syntaxin-binding protein 2 (STXBP2) OTX8GUC4 STXB2_HUMAN Increases Expression [8]
Urea transporter 2 (SLC14A2) OTYI6SX1 UT2_HUMAN Increases Expression [8]
NT-3 growth factor receptor (NTRK3) OTII30MY NTRK3_HUMAN Increases Expression [8]
U11/U12 small nuclear ribonucleoprotein 35 kDa protein (SNRNP35) OTHHFU00 U1SBP_HUMAN Increases Expression [8]
Tafazzin (TAFAZZIN) OTDR57KI TAZ_HUMAN Increases Expression [8]
Drebrin (DBN1) OTZVKG8A DREB_HUMAN Increases Expression [8]
Receptor-type tyrosine-protein phosphatase-like N (PTPRN) OTAP7NOL PTPRN_HUMAN Increases Expression [8]
Tigger transposable element-derived protein 6 (TIGD6) OT8S6ZQW TIGD6_HUMAN Increases Expression [8]
Intestine-specific homeobox (ISX) OTULQRWA ISX_HUMAN Increases Expression [8]
Coiled-coil domain-containing protein 96 (CFAP184) OT71LKTT CCD96_HUMAN Increases Expression [8]
CST complex subunit CTC1 (CTC1) OTRJY7QD CTC1_HUMAN Increases Expression [8]
GON-4-like protein (GON4L) OTWQVLO9 GON4L_HUMAN Increases Expression [8]
Probable E3 SUMO-protein ligase RNF212 (RNF212) OTVBTDNF RN212_HUMAN Increases Expression [8]
Malonate--CoA ligase ACSF3, mitochondrial (ACSF3) OT3WZW8S ACSF3_HUMAN Increases Expression [8]
Enhancer of polycomb homolog 2 (EPC2) OTTG0W9R EPC2_HUMAN Increases Expression [8]
Rho GTPase-activating protein 15 (ARHGAP15) OT9CKHDC RHG15_HUMAN Increases Expression [8]
Puratrophin-1 (PLEKHG4) OT3RBPFL PKHG4_HUMAN Increases Expression [8]
RUN domain-containing protein 3A (RUNDC3A) OTHP1DRS RUN3A_HUMAN Increases Expression [8]
Putative tripartite motif-containing protein 61 (TRIM61) OTDOWYJY TRI61_HUMAN Increases Expression [8]
Transmembrane protein 31 (TMEM31) OTKDPZD4 TMM31_HUMAN Increases Expression [8]
Kidney mitochondrial carrier protein 1 (SLC25A30) OT2VA5PI KMCP1_HUMAN Increases Expression [8]
Clavesin-2 (CLVS2) OTMIUTUF CLVS2_HUMAN Increases Expression [8]
Uncharacterized protein C6orf141 (C6ORF141) OTUS3SIQ CF141_HUMAN Increases Expression [8]
DC-STAMP domain-containing protein 2 (DCST2) OTBFFT75 DCST2_HUMAN Increases Expression [8]
Late cornified envelope-like proline-rich protein 1 (LELP1) OTOQIVV0 LELP1_HUMAN Increases Expression [8]
G kinase-anchoring protein 1 (GKAP1) OTHZRJ56 GKAP1_HUMAN Increases Expression [8]
Protein SLX4IP (SLX4IP) OTRZQJV9 SLX4I_HUMAN Increases Expression [8]
MORN repeat-containing protein 5 (MORN5) OTC7R3YL MORN5_HUMAN Increases Expression [8]
Janus kinase and microtubule-interacting protein 3 (JAKMIP3) OT4EDANR JKIP3_HUMAN Increases Expression [8]
Protein stum homolog (STUM) OTORRHZ9 STUM_HUMAN Increases Expression [8]
TBC1 domain family member 3C (TBC1D3) OT1GW0K2 TBC3C_HUMAN Increases Expression [8]
Speckle-type POZ protein-like (SPOPL) OTS42VUL SPOPL_HUMAN Increases Expression [8]
Tau-tubulin kinase 2 (TTBK2) OT90YSM5 TTBK2_HUMAN Increases Expression [8]
Polypeptide N-acetylgalactosaminyltransferase 17 (GALNT17) OTMF0W2U GLT17_HUMAN Increases Expression [8]
Mitochondrial adenyl nucleotide antiporter SLC25A25 (SLC25A25) OTMNPSNY SCMC2_HUMAN Increases Expression [8]
N-alpha-acetyltransferase 16, NatA auxiliary subunit (NAA16) OTWMA7LK NAA16_HUMAN Increases Expression [8]
Putative ATP-dependent RNA helicase DHX57 (DHX57) OTFAT1PG DHX57_HUMAN Increases Expression [8]
Protein C3orf33 (C3ORF33) OTP8MJAN CC033_HUMAN Increases Expression [8]
tRNA methyltransferase 10 homolog B (TRMT10B) OT3EJP6J TM10B_HUMAN Increases Expression [8]
Complexin-2 (CPLX2) OTU5QWFH CPLX2_HUMAN Increases Expression [8]
Adhesion G-protein coupled receptor D1 (ADGRD1) OT0PVQCW AGRD1_HUMAN Increases Expression [8]
POTE ankyrin domain family member H (POTEH) OTRAB984 POTEH_HUMAN Increases Expression [8]
SLP adapter and CSK-interacting membrane protein (SCIMP) OT9BF7RC SCIMP_HUMAN Increases Expression [8]
Lactase-like protein (LCTL) OTN36T21 LCTL_HUMAN Increases Expression [8]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 7 (ENPP7) OTWOBMQ9 ENPP7_HUMAN Increases Expression [8]
ALK and LTK ligand 1 (ALKAL1) OTZGAZ79 ALKL1_HUMAN Increases Expression [8]
Protein delta homolog 2 (DLK2) OT56Y83S DLK2_HUMAN Increases Expression [8]
Vitamin D 25-hydroxylase (CYP2R1) OT0L1M1D CP2R1_HUMAN Increases Expression [8]
Neuropeptide S receptor (NPSR1) OTVQ0T75 NPSR1_HUMAN Increases Expression [8]
FYVE, RhoGEF and PH domain-containing protein 5 (FGD5) OT5VIRP2 FGD5_HUMAN Increases Expression [8]
Solute carrier organic anion transporter family member 4C1 (SLCO4C1) OTVILUUN SO4C1_HUMAN Increases Expression [8]
Putative glycerol kinase 5 (GK5) OT65U8L1 GLPK5_HUMAN Increases Expression [8]
Mitochondrial S-adenosylmethionine carrier protein (SLC25A26) OTSF2NXD SAMC_HUMAN Increases Expression [8]
Transmembrane and ubiquitin-like domain-containing protein 2 (TMUB2) OTULVRZ0 TMUB2_HUMAN Increases Expression [8]
Endonuclease/exonuclease/phosphatase family domain-containing protein 1 (EEPD1) OTTOGO05 EEPD1_HUMAN Increases Expression [8]
Activity-regulated cytoskeleton-associated protein (ARC) OTN2QQPG ARC_HUMAN Increases Expression [8]
PHD finger-like domain-containing protein 5A (PHF5A) OTS94JFM PHF5A_HUMAN Increases Expression [8]
Highly divergent homeobox (HDX) OTXD5MU6 HDX_HUMAN Increases Expression [8]
LisH domain-containing protein ARMC9 (ARMC9) OT0MZER2 ARMC9_HUMAN Increases Expression [8]
Transmembrane protease serine 9 (TMPRSS9) OT7ETD15 TMPS9_HUMAN Increases Expression [8]
Podocan (PODN) OTV3P7P5 PODN_HUMAN Increases Expression [8]
FERM domain-containing protein 5 (FRMD5) OTC73XJK FRMD5_HUMAN Increases Expression [8]
DnaJ homolog subfamily B member 7 (DNAJB7) OT4BOECZ DNJB7_HUMAN Increases Expression [8]
Large ribosomal subunit protein uL10m (MRPL10) OTPVFZYT RM10_HUMAN Increases Expression [8]
Serine/threonine-protein kinase Nek8 (NEK8) OT8AD4JC NEK8_HUMAN Increases Expression [8]
Telomerase-binding protein EST1A (SMG6) OTRCEJQL EST1A_HUMAN Increases Expression [8]
Amphoterin-induced protein 1 (AMIGO1) OT2EPDFC AMGO1_HUMAN Increases Expression [8]
Proline and serine-rich protein 2 (PROSER2) OT1SX3LS PRSR2_HUMAN Increases Expression [8]
Extracellular matrix organizing protein FRAS1 (FRAS1) OTLPESF3 FRAS1_HUMAN Increases Expression [8]
Spermatogenesis-associated protein 2-like protein (SPATA2L) OTER1D66 SPA2L_HUMAN Increases Expression [8]
Epidermal growth factor-like protein 6 (EGFL6) OT331X59 EGFL6_HUMAN Increases Expression [8]
F-box only protein 16 (FBXO16) OTTEJJVJ FBX16_HUMAN Increases Expression [8]
Cadherin-like protein 26 (CDH26) OTFW5YN6 CAD26_HUMAN Increases Expression [8]
MICAL-like protein 2 (MICALL2) OT1IQM3K MILK2_HUMAN Increases Expression [8]
Dynein regulatory complex subunit 7 (DRC7) OTGURR1R DRC7_HUMAN Increases Expression [8]
Collagen alpha-1(XXVII) chain (COL27A1) OTQ5VDRH CORA1_HUMAN Increases Expression [8]
Gap junction delta-3 protein (GJD3) OT1WZFXO CXD3_HUMAN Increases Expression [8]
Cardiomyopathy-associated protein 5 (CMYA5) OTYV0RME CMYA5_HUMAN Increases Expression [8]
T-cell activation inhibitor, mitochondrial (TCAIM) OTOBD7YO TCAIM_HUMAN Increases Expression [8]
Thioredoxin domain-containing protein 3 (NME8) OT4RULP5 TXND3_HUMAN Increases Expression [8]
Fibrinogen C domain-containing protein 1 (FIBCD1) OTSVT07B FBCD1_HUMAN Increases Expression [8]
Sperm-associated microtubule inner protein 4 (SPMIP4) OTSDTMZP SMIP4_HUMAN Increases Expression [8]
Protein SREK1IP1 (SREK1IP1) OTI29LKO SR1IP_HUMAN Increases Expression [8]
Dynein axonemal assembly factor 3 (DNAAF3) OT3OHO0O DAAF3_HUMAN Increases Expression [8]
Protein boule-like (BOLL) OT5FAEJJ BOLL_HUMAN Increases Expression [8]
Phospholipid-transporting ATPase IG (ATP11C) OTKMV2K5 AT11C_HUMAN Increases Expression [8]
Proprotein convertase subtilisin/kexin type 9 (PCSK9) OTI0DU9Y PCSK9_HUMAN Increases Expression [8]
Trinucleotide repeat-containing gene 6A protein (TNRC6A) OT493IOM TNR6A_HUMAN Increases Expression [8]
Transmembrane protein 161B (TMEM161B) OTHVICQS T161B_HUMAN Increases Expression [8]
Myosin-IIIa (MYO3A) OTPM8PHS MYO3A_HUMAN Increases Expression [8]
Folliculin (FLCN) OTVM78XM FLCN_HUMAN Increases Expression [8]
DNA helicase B (HELB) OT769EC5 HELB_HUMAN Increases Expression [8]
Olfactory receptor 9Q2 (OR9Q2) OT8FQCR1 OR9Q2_HUMAN Increases Expression [8]
Olfactory receptor 52N2 (OR52N2) OTR9P3MX O52N2_HUMAN Increases Expression [8]
Olfactory receptor 4C16 (OR4C16) OT2E6H5F OR4CG_HUMAN Increases Expression [8]
Olfactory receptor 6T1 (OR6T1) OT2EEZ75 OR6T1_HUMAN Increases Expression [8]
Olfactory receptor 4F5 (OR4F5) OTKDDVIS OR4F5_HUMAN Increases Expression [8]
Killer cell immunoglobulin-like receptor 2DL5B (KIR2DL5B) OTSV0JL9 KI2LB_HUMAN Increases Expression [8]
GTPase RhebL1 (RHEBL1) OTPOMM5J REBL1_HUMAN Increases Expression [8]
Ermin (ERMN) OTS3PBOH ERMIN_HUMAN Increases Expression [8]
Ras and Rab interactor 3 (RIN3) OT5Z6F8O RIN3_HUMAN Increases Expression [8]
DEP domain-containing mTOR-interacting protein (DEPTOR) OTCBP1BT DPTOR_HUMAN Increases Expression [8]
Protein cornichon homolog 3 (CNIH3) OTNLZ2QS CNIH3_HUMAN Increases Expression [8]
Protein FAM81A (FAM81A) OT2MA138 FA81A_HUMAN Increases Expression [8]
Ciliary microtubule-associated protein 3 (CIMAP3) OT8RL1WO CMAP3_HUMAN Increases Expression [8]
Caskin-2 (CASKIN2) OTCIT4EF CSKI2_HUMAN Increases Expression [8]
Dynein axonemal heavy chain 7 (DNAH7) OTTI8FRY DYH7_HUMAN Increases Expression [8]
Nanos homolog 1 (NANOS1) OT3UNZZY NANO1_HUMAN Increases Expression [8]
Rho GTPase-activating protein 45 (ARHGAP45) OTL86FEQ HMHA1_HUMAN Increases Expression [8]
Protein TFG (TFG) OT2KJENI TFG_HUMAN Increases Expression [8]
Transcription factor AP-2 gamma (TFAP2C) OTUDIW05 AP2C_HUMAN Increases Expression [8]
Prospero homeobox protein 1 (PROX1) OT68R6IO PROX1_HUMAN Increases Expression [8]
Coronin-2A (CORO2A) OTVK7PK3 COR2A_HUMAN Increases Expression [8]
Probable ATP-dependent RNA helicase DDX17 (DDX17) OTXRMMBP DDX17_HUMAN Increases Expression [8]
Semaphorin-4D (SEMA4D) OTJ5WDV9 SEM4D_HUMAN Increases Expression [8]
Transcription factor ATOH1 (ATOH1) OTBZYG2R ATOH1_HUMAN Increases Expression [8]
RNA-binding protein with multiple splicing (RBPMS) OT1RDKR9 RBPMS_HUMAN Increases Expression [8]
Thymic stromal lymphopoietin (TSLP) OT52AOIG TSLP_HUMAN Increases Expression [8]
Immunoglobulin superfamily member 8 (IGSF8) OTU22IKI IGSF8_HUMAN Increases Expression [8]
F-box only protein 32 (FBXO32) OTUE978R FBX32_HUMAN Increases Expression [8]
Oxysterol-binding protein 2 (OSBP2) OTDGLB4J OSBP2_HUMAN Increases Expression [8]
Galactose-3-O-sulfotransferase 3 (GAL3ST3) OTOXAVMS G3ST3_HUMAN Increases Expression [8]
Peptidyl-prolyl cis-trans isomerase FKBP10 (FKBP10) OTYKLW1K FKB10_HUMAN Increases Expression [8]
Engulfment and cell motility protein 3 (ELMO3) OTQHO9VM ELMO3_HUMAN Increases Expression [8]
ELL-associated factor 2 (EAF2) OTSOET5L EAF2_HUMAN Increases Expression [8]
Reticulocalbin-3 (RCN3) OTHWE0NF RCN3_HUMAN Increases Expression [8]
Ras-related protein Rab-39B (RAB39B) OTDCLLT0 RB39B_HUMAN Increases Expression [8]
RNA-binding protein 33 (RBM33) OT4JQ9YG RBM33_HUMAN Increases Expression [8]
CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7) OTI7Q2JW CKLF7_HUMAN Increases Expression [8]
Protein FAM89A (FAM89A) OTNASAXT FA89A_HUMAN Increases Expression [8]
Uncharacterized protein C16orf74 (C16ORF74) OTLLVHH0 CP074_HUMAN Increases Expression [8]
RCC1-like G exchanging factor-like protein (RCC1L) OT97PWCG RCC1L_HUMAN Increases Expression [8]
ATP-binding cassette sub-family C member 11 (ABCC11) OTVHL7OR MRP8_HUMAN Increases Expression [8]
CUGBP Elav-like family member 6 (CELF6) OT111JZ3 CELF6_HUMAN Increases Expression [8]
Membrane-spanning 4-domains subfamily A member 14 (MS4A14) OTX8BPFZ M4A14_HUMAN Increases Expression [8]
Melanoma-associated antigen D4 (MAGED4B) OTO37U7W MAGD4_HUMAN Increases Expression [8]
PDZ and LIM domain protein 2 (PDLIM2) OTEURRPD PDLI2_HUMAN Increases Expression [8]
Spermatogenesis-associated protein 17 (SPATA17) OT6SK923 SPT17_HUMAN Increases Expression [8]
Kinesin-like protein KIF16B (KIF16B) OTDWIFQ2 KI16B_HUMAN Increases Expression [8]
Fc receptor-like protein 2 (FCRL2) OT0RLDOD FCRL2_HUMAN Increases Expression [8]
Fc receptor-like protein 1 (FCRL1) OTXOYT29 FCRL1_HUMAN Increases Expression [8]
Coiled-coil domain-containing protein 17 (CCDC17) OTXXE5AN CCD17_HUMAN Increases Expression [8]
FYVE, RhoGEF and PH domain-containing protein 4 (FGD4) OTYXJQCW FGD4_HUMAN Increases Expression [8]
DGAT1/2-independent enzyme synthesizing storage lipids (TMEM68) OTNSZSH7 DIESL_HUMAN Increases Expression [8]
Fc receptor-like protein 3 (FCRL3) OTIFXFWL FCRL3_HUMAN Increases Expression [8]
CCA tRNA nucleotidyltransferase 1, mitochondrial (TRNT1) OTD57ILL TRNT1_HUMAN Increases Expression [8]
Sorting nexin-18 (SNX18) OT68KT3X SNX18_HUMAN Increases Expression [8]
Tribbles homolog 3 (TRIB3) OTG5OS7X TRIB3_HUMAN Increases Expression [8]
Mitochondrial import inner membrane translocase subunit Tim17-A (TIMM17A) OTVFRL8G TI17A_HUMAN Increases Expression [8]
DNA endonuclease RBBP8 (RBBP8) OTRHJ3GI CTIP_HUMAN Increases Expression [8]
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1A) OTVTB5R5 PI51A_HUMAN Increases Expression [8]
Protein arginine N-methyltransferase 1 (PRMT1) OTN8GTXW ANM1_HUMAN Increases Expression [8]
BAG family molecular chaperone regulator 1 (BAG1) OTRQNIA4 BAG1_HUMAN Increases Expression [8]
Cyclic AMP-dependent transcription factor ATF-6 beta (ATF6B) OTT2ZGSR ATF6B_HUMAN Increases Expression [8]
Growth/differentiation factor 15 (GDF15) OTWQN50N GDF15_HUMAN Increases Expression [8]
BTB/POZ domain-containing protein KCTD14 (KCTD14) OTG8O2EZ KCD14_HUMAN Increases Expression [8]
Rho GTPase-activating protein 9 (ARHGAP9) OTJNHX96 RHG09_HUMAN Increases Expression [8]
Protein fuzzy homolog (FUZ) OTC427QQ FUZZY_HUMAN Increases Expression [8]
Histone H2A.J (H2AJ) OTVA4XTW H2AJ_HUMAN Increases Expression [8]
Protein crumbs homolog 3 (CRB3) OTQKPTMU CRUM3_HUMAN Increases Expression [8]
Programmed cell death protein 10 (PDCD10) OTCHJTSF PDC10_HUMAN Increases Expression [8]
Glutathione-specific gamma-glutamylcyclotransferase 1 (CHAC1) OTJGE772 CHAC1_HUMAN Increases Expression [8]
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase (ALG12) OTVAT4OJ ALG12_HUMAN Increases Expression [8]
Kinesin-like protein KIFC1 (KIFC1) OTNQDS00 KIFC1_HUMAN Increases Expression [8]
Replication initiator 1 (REPIN1) OTVTPXNX REPI1_HUMAN Increases Expression [8]
FUN14 domain-containing protein 2 (FUNDC2) OTY3TQM5 FUND2_HUMAN Increases Expression [8]
Tapasin-related protein (TAPBPL) OTTS1YNP TPSNR_HUMAN Increases Expression [8]
Krueppel-like factor 16 (KLF16) OTTPV4NB KLF16_HUMAN Increases Expression [8]
NF-kappa-B inhibitor zeta (NFKBIZ) OTU728KS IKBZ_HUMAN Increases Expression [8]
ATP-binding cassette sub-family A member 2 (ABCA2) OTVSYK0X ABCA2_HUMAN Increases Expression [8]
Protein Niban 1 (NIBAN1) OTYOLI12 NIBA1_HUMAN Increases Expression [8]
Forkhead box protein P3 (FOXP3) OTA9Z9OC FOXP3_HUMAN Increases Expression [8]
Testis-specific gene 10 protein (TSGA10) OTIF1O1T TSG10_HUMAN Increases Expression [8]
Sperm flagellar protein 2 (SPEF2) OTO04K1T SPEF2_HUMAN Increases Expression [8]
Olfactory receptor 2B2 (OR2B2) OTW2XE6D OR2B2_HUMAN Increases Expression [8]
Carbohydrate sulfotransferase 6 (CHST6) OTXD2IWK CHST6_HUMAN Increases Expression [8]
Extracellular glycoprotein lacritin (LACRT) OTROSU7Z LACRT_HUMAN Increases Expression [8]
Neuroblastoma breakpoint family member 3 (NBPF3) OTRM16MN NBPF3_HUMAN Increases Expression [8]
Mitochondrial glutamate carrier 2 (SLC25A18) OT64J803 GHC2_HUMAN Increases Expression [8]
Myosin light chain kinase 2, skeletal/cardiac muscle (MYLK2) OTVISMUK MYLK2_HUMAN Increases Expression [8]
Olfactory receptor 2D2 (OR2D2) OTXTAXN1 OR2D2_HUMAN Increases Expression [8]
Caspase recruitment domain-containing protein 9 (CARD9) OTJ81AWD CARD9_HUMAN Increases Expression [8]
Enhancer of polycomb homolog 1 (EPC1) OT3Q25ND EPC1_HUMAN Increases Expression [8]
Testis-specific Y-encoded-like protein 2 (TSPYL2) OTGGW2EF TSYL2_HUMAN Increases Expression [8]
Solute carrier organic anion transporter family member 5A1 (SLCO5A1) OTNXXTH0 SO5A1_HUMAN Increases Expression [8]
BolA-like protein 2 (BOLA2) OTVZP6YB BOLA2_HUMAN Increases Expression [8]
Semaphorin-6B (SEMA6B) OT3VVVUO SEM6B_HUMAN Increases Expression [8]
Ribokinase (RBKS) OTDG01Y9 RBSK_HUMAN Increases Expression [8]
Glutathione S-transferase omega-2 (GSTO2) OTVDSNLH GSTO2_HUMAN Increases Expression [8]
Alpha-1,3/1,6-mannosyltransferase ALG2 (ALG2) OT77B384 ALG2_HUMAN Increases Expression [8]
Ankyrin repeat and SOCS box protein 7 (ASB7) OT9SAYDY ASB7_HUMAN Increases Expression [8]
Coiled-coil domain-containing protein 134 (CCDC134) OT70OQQV CC134_HUMAN Increases Expression [8]
Nucleolar protein 6 (NOL6) OT6OIF2Q NOL6_HUMAN Increases Expression [8]
Dedicator of cytokinesis protein 5 (DOCK5) OT63I0CL DOCK5_HUMAN Increases Expression [8]
Probable ATP-dependent RNA helicase DDX31 (DDX31) OTNWY581 DDX31_HUMAN Increases Expression [8]
Metal transporter CNNM2 (CNNM2) OTZHO8WU CNNM2_HUMAN Increases Expression [8]
Inositol-pentakisphosphate 2-kinase (IPPK) OT251AAR IPPK_HUMAN Increases Expression [8]
Histone-lysine N-methyltransferase EHMT1 (EHMT1) OT6QC8GK EHMT1_HUMAN Increases Expression [8]
Dysbindin domain-containing protein 1 (DBNDD1) OTATKUA8 DBND1_HUMAN Increases Expression [8]
EF-hand and coiled-coil domain-containing protein 1 (EFCC1) OTW20MOF EFCC1_HUMAN Increases Expression [8]
Potassium channel subfamily K member 12 (KCNK12) OTFP82TK KCNKC_HUMAN Increases Expression [8]
Peptide deformylase, mitochondrial (PDF) OTZ75ZK5 DEFM_HUMAN Increases Expression [8]
Rho guanine nucleotide exchange factor 10-like protein (ARHGEF10L) OTUAMHIZ ARGAL_HUMAN Increases Expression [8]
3',5'-cyclic-AMP phosphodiesterase 7B (PDE7B) OTK3SHT2 PDE7B_HUMAN Increases Expression [8]
Ras-related protein Rab-9B (RAB9B) OTNWICHJ RAB9B_HUMAN Increases Expression [8]
5'(3')-deoxyribonucleotidase, mitochondrial (NT5M) OTJF73BA NT5M_HUMAN Increases Expression [8]
CD320 antigen (CD320) OT8CSNU2 CD320_HUMAN Increases Expression [8]
Uncharacterized protein C11orf16 (C11ORF16) OTG0887Q CK016_HUMAN Increases Expression [8]
G-protein coupled receptor family C group 5 member C (GPRC5C) OT45AJT3 GPC5C_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase TRIM36 (TRIM36) OT37JQ8Y TRI36_HUMAN Increases Expression [8]
PR domain zinc finger protein 8 (PRDM8) OTRA3265 PRDM8_HUMAN Increases Expression [8]
CDC42 small effector protein 1 (CDC42SE1) OTV3MRFE C42S1_HUMAN Increases Expression [8]
Rho GTPase-activating protein 35 (ARHGAP35) OTJ8POG0 RHG35_HUMAN Increases Expression [8]
Three-prime repair exonuclease 1 (TREX1) OTQG7K12 TREX1_HUMAN Increases Expression [8]
BMP-2-inducible protein kinase (BMP2K) OT0IRJBY BMP2K_HUMAN Increases Expression [8]
StAR-related lipid transfer protein 5 (STARD5) OTH0PF56 STAR5_HUMAN Increases Expression [8]
PAK4-inhibitor INKA2 (INKA2) OT9RA64U INKA2_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase RNF146 (RNF146) OTE4CO7E RN146_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase RNF19A (RNF19A) OTKWCV80 RN19A_HUMAN Increases Expression [8]
Trimethyllysine dioxygenase, mitochondrial (TMLHE) OTH4ZLJP TMLH_HUMAN Increases Expression [8]
FGFR1 oncogene partner 2 (FGFR1OP2) OTAHO1ZC FGOP2_HUMAN Increases Expression [8]
Spermine oxidase (SMOX) OT11E62Y SMOX_HUMAN Increases Expression [8]
3-oxoacyl- synthase, mitochondrial (OXSM) OTMDWHOM OXSM_HUMAN Increases Expression [8]
DNA damage-inducible transcript 4 protein (DDIT4) OTHY8SY4 DDIT4_HUMAN Increases Expression [8]
Glucose-fructose oxidoreductase domain-containing protein 1 (GFOD1) OTOHDWX1 GFOD1_HUMAN Increases Expression [8]
Kelch-like protein 28 (KLHL28) OTA051QG KLH28_HUMAN Increases Expression [8]
DnaJ homolog subfamily B member 12 (DNAJB12) OTL2ZFTX DJB12_HUMAN Increases Expression [8]
Protein EURL homolog (C21ORF91) OTERV7NW EURL_HUMAN Increases Expression [8]
Retinol dehydrogenase 8 (RDH8) OTSFFV9B RDH8_HUMAN Increases Expression [8]
Taste receptor type 2 member 10 (TAS2R10) OT4RWZZD T2R10_HUMAN Increases Expression [8]
Eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3) OT0DZGY4 E2AK3_HUMAN Increases Expression [8]
Adenosine deaminase 2 (ADA2) OTGCV24S ADA2_HUMAN Increases Expression [8]
Mediator of RNA polymerase II transcription subunit 11 (MED11) OTBXTVGO MED11_HUMAN Increases Expression [8]
Kallikrein-14 (KLK14) OTILMO80 KLK14_HUMAN Increases Expression [8]
Actin-related protein 3B (ACTR3B) OTNEC9UT ARP3B_HUMAN Increases Expression [8]
Kinesin-like protein KIF17 (KIF17) OTHASX9G KIF17_HUMAN Increases Expression [8]
Myelin expression factor 2 (MYEF2) OTSXZ356 MYEF2_HUMAN Increases Expression [8]
DnaJ homolog subfamily B member 9 (DNAJB9) OT38EQT6 DNJB9_HUMAN Increases Expression [8]
DNA polymerase lambda (POLL) OTZ24QGM DPOLL_HUMAN Increases Expression [8]
Transcription factor 20 (TCF20) OT8LQAOV TCF20_HUMAN Increases Expression [8]
HMG domain-containing protein 4 (HMGXB4) OTB1QT9U HMGX4_HUMAN Increases Expression [8]
Protein FAM153A (FAM153A) OTNHG4S2 F153A_HUMAN Increases Expression [8]
Brain-specific angiogenesis inhibitor 1-associated protein 2-like protein 1 (BAIAP2L1) OTZ71SK9 BI2L1_HUMAN Increases Expression [8]
Krueppel-like factor 15 (KLF15) OTGMQMVR KLF15_HUMAN Increases Expression [8]
Death-associated protein kinase 2 (DAPK2) OTWODUQG DAPK2_HUMAN Increases Expression [8]
CCR4-NOT transcription complex subunit 7 (CNOT7) OTJBKCPI CNOT7_HUMAN Increases Expression [8]
Potassium voltage-gated channel subfamily E regulatory beta subunit 5 (KCNE5) OTF4JYGZ KCNE5_HUMAN Increases Expression [8]
Probable E3 ubiquitin-protein ligase MID2 (MID2) OTAAQNZA TRIM1_HUMAN Increases Expression [8]
Tubulointerstitial nephritis antigen (TINAG) OTY7BSD7 TINAG_HUMAN Increases Expression [8]
SERTA domain-containing protein 3 (SERTAD3) OTQP9BWM SRTD3_HUMAN Increases Expression [8]
Uncharacterized protein C3orf18 (C3ORF18) OTSFU1NZ CC018_HUMAN Increases Expression [8]
Protein Z-dependent protease inhibitor (SERPINA10) OTZ8OZ67 ZPI_HUMAN Increases Expression [8]
Solute carrier family 13 member 4 (SLC13A4) OTP3N8N3 S13A4_HUMAN Increases Expression [8]
Sarcosine dehydrogenase, mitochondrial (SARDH) OTQ49Q27 SARDH_HUMAN Increases Expression [8]
Alpha-1,3-mannosyl-glycoprotein 4-beta-N-acetylglucosaminyltransferase A (MGAT4A) OT0ZW5FM MGT4A_HUMAN Increases Expression [8]
ALK tyrosine kinase receptor (ALK) OTV3P4V8 ALK_HUMAN Increases Expression [8]
Calpain-11 (CAPN11) OTEHK57V CAN11_HUMAN Increases Expression [8]
Protocadherin gamma-C3 (PCDHGC3) OTDXTUMI PCDGK_HUMAN Increases Expression [8]
Exonuclease 1 (EXO1) OTI87RS5 EXO1_HUMAN Increases Expression [8]
Calcium/calmodulin-dependent protein kinase type II subunit alpha (CAMK2A) OTJGX19T KCC2A_HUMAN Increases Expression [8]
E3 ubiquitin-protein ligase RNF6 (RNF6) OTNAXM6D RNF6_HUMAN Increases Expression [8]
Phospholipase A-2-activating protein (PLAA) OTZ7NJGA PLAP_HUMAN Increases Expression [8]
Coiled-coil domain-containing protein 9 (CCDC9) OT4SKM1W CCDC9_HUMAN Increases Expression [8]
Pygopus homolog 1 (PYGO1) OT8L4L2R PYGO1_HUMAN Increases Expression [8]
Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) OT8M52QY LMBL1_HUMAN Increases Expression [8]
Jerky protein homolog-like (JRKL) OTHZNWS4 JERKL_HUMAN Increases Expression [8]
Malignant fibrous histiocytoma-amplified sequence 1 (MFHAS1) OTS922CJ MFHA1_HUMAN Increases Expression [8]
Tubulin monoglycylase TTLL3 (TTLL3) OT7JWXHA TTLL3_HUMAN Increases Expression [8]
Protocadherin alpha-C2 (PCDHAC2) OTNFJS0M PCDC2_HUMAN Increases Expression [8]
Mitochondrial import inner membrane translocase subunit Tim13 (TIMM13) OTYZQJD3 TIM13_HUMAN Increases Expression [8]
Transient receptor potential cation channel subfamily V member 2 (TRPV2) OT0A9AVD TRPV2_HUMAN Increases Expression [8]
Transcription factor ETV7 (ETV7) OTIAADPA ETV7_HUMAN Increases Expression [8]
NAD-dependent protein lipoamidase sirtuin-4, mitochondrial (SIRT4) OT5S0J23 SIR4_HUMAN Increases Expression [8]
Proton-coupled zinc antiporter SLC30A1 (SLC30A1) OTY8J0S4 ZNT1_HUMAN Increases Expression [8]
Probable ATP-dependent RNA helicase DDX49 (DDX49) OT13VWB7 DDX49_HUMAN Increases Expression [8]
Dual specificity protein phosphatase 10 (DUSP10) OTNG467B DUS10_HUMAN Increases Expression [8]
Bile salt export pump (ABCB11) OTRU7THO ABCBB_HUMAN Decreases Activity [30]
Stearoyl-CoA desaturase (SCD) OTB1073G SCD_HUMAN Increases Expression [31]
Acyl-CoA 6-desaturase (FADS2) OTUX531P FADS2_HUMAN Increases Expression [31]
Heterogeneous nuclear ribonucleoprotein A1 (HNRNPA1) OTIRPN6B ROA1_HUMAN Increases Expression [32]
Liver carboxylesterase 1 (CES1) OT9L0LR8 EST1_HUMAN Increases Expression [32]
Aldo-keto reductase family 1 member C1 (AKR1C1) OTQKR4CM AK1C1_HUMAN Increases Expression [32]
T-box transcription factor TBX3 (TBX3) OTM64N7K TBX3_HUMAN Increases Expression [12]
Trans-Golgi network integral membrane protein 2 (TGOLN2) OTM647IV TGON2_HUMAN Increases Expression [12]
Pendrin (SLC26A4) OTXUTLVS S26A4_HUMAN Decreases Expression [33]
Serine/threonine-protein kinase/endoribonuclease IRE1 (ERN1) OTY9R6FZ ERN1_HUMAN Increases Phosphorylation [34]
Diacylglycerol O-acyltransferase 1 (DGAT1) OTL104WL DGAT1_HUMAN Increases Expression [34]
Ubiquitin-like modifier-activating enzyme ATG7 (ATG7) OTVT4YA1 ATG7_HUMAN Increases Expression [35]
Phospholipid-transporting ATPase ABCA1 (ABCA1) OT94G6BQ ABCA1_HUMAN Decreases Expression [36]
Zinc finger protein SNAI1 (SNAI1) OTDPYAMC SNAI1_HUMAN Decreases Expression [10]
Superoxide dismutase (SOD1) OT39TA1L SODC_HUMAN Decreases Expression [37]
Epidermal growth factor receptor (EGFR) OTAPLO1S EGFR_HUMAN Decreases Phosphorylation [10]
Angiotensinogen (AGT) OTBZLYR3 ANGT_HUMAN Increases Expression [38]
Low-density lipoprotein receptor (LDLR) OTH559LU LDLR_HUMAN Decreases Expression [39]
Thyrotropin subunit beta (TSHB) OTFDI39D TSHB_HUMAN Increases Expression [40]
Thyroglobulin (TG) OT3ELHIJ THYG_HUMAN Decreases Expression [33]
Tumor necrosis factor (TNF) OT4IE164 TNFA_HUMAN Increases Expression [37]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Increases Expression [37]
Serotransferrin (TF) OT41PEMS TRFE_HUMAN Increases Expression [23]
Ferritin light chain (FTL) OTYQA8A6 FRIL_HUMAN Increases Expression [23]
Metallothionein-2 (MT2A) OTHOACHD MT2_HUMAN Increases Expression [23]
Catalase (CAT) OTHEBX9R CATA_HUMAN Decreases Expression [37]
Apolipoprotein B-100 (APOB) OTH0UOCZ APOB_HUMAN Decreases Expression [36]
Superoxide dismutase , mitochondrial (SOD2) OTIWXGZ9 SODM_HUMAN Decreases Expression [37]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Decreases Expression [11]
Metallothionein-1E (MT1E) OTXJKU4Y MT1E_HUMAN Increases Expression [23]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Decreases Activity [41]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Increases Phosphorylation [42]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Increases Expression [43]
Beta-hexosaminidase subunit alpha (HEXA) OT48T897 HEXA_HUMAN Increases Expression [44]
Thyroid peroxidase (TPO) OTJJLL20 PERT_HUMAN Decreases Expression [33]
Glutathione peroxidase 1 (GPX1) OTE2O72Q GPX1_HUMAN Decreases Expression [37]
Cathepsin D (CTSD) OTQZ36F3 CATD_HUMAN Affects Cleavage [44]
Beta-2 adrenergic receptor (ADRB2) OTSDOX4Q ADRB2_HUMAN Decreases Expression [45]
Procathepsin L (CTSL) OTYTUW29 CATL1_HUMAN Affects Cleavage [44]
Cathepsin B (CTSB) OTP9G5QB CATB_HUMAN Affects Cleavage [44]
Beta-1 adrenergic receptor (ADRB1) OTQBWN4U ADRB1_HUMAN Decreases Expression [45]
Insulin-like growth factor-binding protein 1 (IGFBP1) OT6UQV2K IBP1_HUMAN Increases Expression [46]
Glutathione S-transferase A2 (GSTA2) OTW7UB1H GSTA2_HUMAN Increases Expression [23]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Increases Expression [33]
Apoptosis regulator Bcl-2 (BCL2) OT9DVHC0 BCL2_HUMAN Decreases Expression [37]
Thyroid hormone receptor alpha (THRA) OTKRLVD7 THA_HUMAN Affects Binding [47]
Endoplasmic reticulum chaperone BiP (HSPA5) OTFUIRAO BIP_HUMAN Increases Expression [42]
Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) OTA675TJ GTR1_HUMAN Decreases Expression [23]
Cadherin-1 (CDH1) OTFJMXPM CADH1_HUMAN Increases Expression [10]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Increases Expression [12]
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2) OT1LQSGX MTDC_HUMAN Increases Expression [23]
Platelet glycoprotein 4 (CD36) OT5CZWKY CD36_HUMAN Decreases Expression [36]
Integrin beta-5 (ITGB5) OT21MF51 ITB5_HUMAN Decreases Expression [12]
Cyclic AMP-dependent transcription factor ATF-4 (ATF4) OTRFV19J ATF4_HUMAN Decreases Expression [11]
Cadherin-2 (CDH2) OTH0Y56P CADH2_HUMAN Decreases Expression [10]
Transcription factor EB (TFEB) OTJUJJQY TFEB_HUMAN Affects Localization [44]
Nuclear factor NF-kappa-B p105 subunit (NFKB1) OTNRRD8I NFKB1_HUMAN Affects Expression [11]
Interleukin-10 (IL10) OTIRFRXC IL10_HUMAN Decreases Expression [37]
Ribosomal protein S6 kinase beta-1 (RPS6KB1) OTAELNGX KS6B1_HUMAN Decreases Phosphorylation [35]
Alanine aminotransferase 1 (GPT) OTOXOA0Q ALAT1_HUMAN Increases Activity [48]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Decreases Phosphorylation [10]
Calreticulin (CALR) OTYD2TR1 CALR_HUMAN Increases Expression [23]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Decreases Phosphorylation [10]
RAC-alpha serine/threonine-protein kinase (AKT1) OT8H2YY7 AKT1_HUMAN Decreases Phosphorylation [35]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Affects Expression [11]
Sterol regulatory element-binding protein 1 (SREBF1) OTWBRPAI SRBP1_HUMAN Increases Expression [34]
Peroxisome proliferator-activated receptor gamma (PPARG) OTHMARHO PPARG_HUMAN Decreases Expression [11]
Signal transducer and activator of transcription 1-alpha/beta (STAT1) OTLMBUZ6 STAT1_HUMAN Decreases Expression [11]
Caspase-3 (CASP3) OTIJRBE7 CASP3_HUMAN Increases Expression [49]
Excitatory amino acid transporter 1 (SLC1A3) OTILR60R EAA1_HUMAN Increases Expression [23]
Glutamate--cysteine ligase regulatory subunit (GCLM) OT6CP234 GSH0_HUMAN Increases Expression [23]
Fatty acid synthase (FASN) OTFII9KG FAS_HUMAN Affects Expression [36]
Glycogen synthase kinase-3 beta (GSK3B) OTL3L14B GSK3B_HUMAN Decreases Phosphorylation [10]
Type I iodothyronine deiodinase (DIO1) OTFYLYJ0 IOD1_HUMAN Decreases Activity [50]
Carnitine O-palmitoyltransferase 1, liver isoform (CPT1A) OTI862QH CPT1A_HUMAN Affects Expression [36]
Tumor necrosis factor ligand superfamily member 10 (TNFSF10) OT4PXBTA TNF10_HUMAN Increases Response To Substance [26]
Signal transducer and activator of transcription 2 (STAT2) OTO9G2RZ STAT2_HUMAN Decreases Expression [11]
ATP-citrate synthase (ACLY) OTRL9ZRP ACLY_HUMAN Increases Expression [51]
5'-AMP-activated protein kinase catalytic subunit alpha-2 (PRKAA2) OTU1KZPV AAPK2_HUMAN Increases Phosphorylation [35]
Microsomal triglyceride transfer protein large subunit (MTTP) OTNUVSDT MTP_HUMAN Decreases Expression [46]
Caspase-7 (CASP7) OTAPJ040 CASP7_HUMAN Increases Activity [52]
Hepatocyte nuclear factor 3-alpha (FOXA1) OTEBY0TD FOXA1_HUMAN Decreases Expression [46]
Actin, aortic smooth muscle (ACTA2) OTEDLG8E ACTA_HUMAN Increases Expression [9]
Metallothionein-1H (MT1H) OT0MVBM6 MT1H_HUMAN Increases Expression [23]
Pro-neuregulin-1, membrane-bound isoform (NRG1) OTZO6F1X NRG1_HUMAN Increases Expression [23]
DNA-binding protein inhibitor ID-2 (ID2) OT0U1D53 ID2_HUMAN Increases Expression [12]
Peroxiredoxin-1 (PRDX1) OTZ3BEC4 PRDX1_HUMAN Decreases Expression [23]
Apoptosis regulator BAX (BAX) OTAW0V4V BAX_HUMAN Increases Expression [49]
Peroxisomal bifunctional enzyme (EHHADH) OTBAAHL5 ECHP_HUMAN Decreases Expression [46]
5'-AMP-activated protein kinase catalytic subunit alpha-1 (PRKAA1) OT7TNF0L AAPK1_HUMAN Increases Phosphorylation [35]
Eukaryotic translation initiation factor 4E-binding protein 1 (EIF4EBP1) OTHBQVD5 4EBP1_HUMAN Decreases Phosphorylation [35]
Metal regulatory transcription factor 1 (MTF1) OTJWVLLF MTF1_HUMAN Decreases Expression [11]
Nuclear factor erythroid 2-related factor 2 (NFE2L2) OT0HENJ5 NF2L2_HUMAN Increases Expression [23]
Hypoxia-inducible factor 1-alpha (HIF1A) OTADSC03 HIF1A_HUMAN Decreases Expression [11]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Decreases Activity [41]
Metallothionein-1M (MT1M) OTVT8PLU MT1M_HUMAN Increases Expression [23]
Phospholipase A2 group XV (PLA2G15) OT6VJTPA PAG15_HUMAN Affects Expression [36]
Sodium/iodide cotransporter (SLC5A5) OTU7E9G7 SC5A5_HUMAN Decreases Expression [33]
Bcl-2-binding component 3, isoforms 3/4 (BBC3) OTUAXDAY BBC3B_HUMAN Increases Expression [23]
Eukaryotic translation initiation factor 2A (EIF2A) OTWXELQP EIF2A_HUMAN Increases Phosphorylation [26]
Microtubule-associated proteins 1A/1B light chain 3B (MAP1LC3B) OTUYHB84 MLP3B_HUMAN Increases Lipidation [34]
Very long chain fatty acid elongase 6 (ELOVL6) OTB26UJJ ELOV6_HUMAN Increases Expression [36]
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A) OTHCDQ22 PRGC1_HUMAN Increases Expression [46]
Peroxisomal carnitine O-octanoyltransferase (CROT) OTWK68MM OCTC_HUMAN Decreases Expression [46]
Transcription factor MafF (MAFF) OT9B7MX0 MAFF_HUMAN Increases Expression [23]
Cystine/glutamate transporter (SLC7A11) OTKJ6PXW XCT_HUMAN Increases Expression [23]
Angiopoietin-related protein 3 (ANGPTL3) OTCD5Z9W ANGL3_HUMAN Decreases Expression [46]
Autophagy protein 5 (ATG5) OT4T5SMS ATG5_HUMAN Affects Response To Substance [34]
Cytochrome P450 2A6 (CYP2A6) OT52TWG3 CP2A6_HUMAN Decreases Response To Substance [53]
Potassium voltage-gated channel subfamily KQT member 1 (KCNQ1) OT8SPJNX KCNQ1_HUMAN Increases ADR [54]
Solute carrier organic anion transporter family member 2B1 (SLCO2B1) OTERJ4VQ SO2B1_HUMAN Increases Uptake [55]
Cytochrome P450 2C19 (CYP2C19) OTFMJYYE CP2CJ_HUMAN Decreases Response To Substance [53]
Cytochrome P450 2E1 (CYP2E1) OTHQ17JG CP2E1_HUMAN Decreases Response To Substance [53]
Cytochrome P450 2B6 (CYP2B6) OTOYO4S7 CP2B6_HUMAN Decreases Response To Substance [53]
Cytochrome P450 3A5 (CYP3A5) OTSXFBXB CP3A5_HUMAN Decreases Response To Substance [53]
Cytochrome P450 3A7 (CYP3A7) OTTCDHHM CP3A7_HUMAN Decreases Response To Substance [53]
Cytochrome P450 2C18 (CYP2C18) OTY687L9 CP2CI_HUMAN Decreases Response To Substance [53]
Potassium voltage-gated channel subfamily E member 1 (KCNE1) OTZNQUW9 KCNE1_HUMAN Increases ADR [54]
Potassium voltage-gated channel subfamily H member 2 (KCNH2) OTZX881H KCNH2_HUMAN Increases ADR [56]
------------------------------------------------------------------------------------
⏷ Show the Full List of 627 DOT(s)
Indication(s) of Acetylcysteine
Disease Entry ICD 11 Status REF
Amyloidosis 5D00 Approved [5]
Bronchiectasis CA24 Approved [5]
Bronchitis CA20 Approved [5]
Bulimia nervosa 6B81 Approved [5]
Ischemia-reperfusion injury DB98.B Approved [5]
Liver disease DB90-BD99 Approved [6]
Paracetamol poisoning N.A. Approved [5]

References

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2 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2566).
3 FDA Approved Drug Products from FDA Official Website. 2019. Application Number: (ANDA) 204742.
4 ClinicalTrials.gov (NCT04351763) Amiodarone or Verapamil in COVID-19 Hospitalized Patients With Symptoms. U.S. National Institutes of Health.
5 Acetylcysteine FDA Label
6 Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
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39 Effects of triiodothyronine and amiodarone on the promoter of the human LDL receptor gene. Biochem Biophys Res Commun. 1998 Aug 19;249(2):517-21. doi: 10.1006/bbrc.1998.9174.
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