Details of the Drug-Related molecule(s) Interaction Atlas

General Information of Drug (ID: DMTA5OE)

Drug Name
Azacitidine Drug Info
Synonyms
Azacitidina; Azacitidinum; Azacytidine; Ladakamycin; Mylosar; Vidaza; Mylo sar; Pharmion Brand of Azacitidine;A 2385; Antibiotic U 18496; U 18496; Wr 183027; Azacitidina [INN-Spanish]; Azacitidine [USAN:INN]; Azacitidinum [INN-Latin]; NS-17; Pyrimidine antimetabolite: inhibits nucleic acid replication; U-18496; Vidaz (TN); Vidaza (TN); WR-183027; Azacitidine (JAN/USAN/INN); S-Triazin-2(1H)-one, 4-amino-1-beta-D-ribofuranosyl-(8CI); 2-(beta-D-Ribofuranosyl)-4-amino-1,3,5-triazin-2-one; 4-Amino-1-(beta-D-ribofuranosyl)-1,3,5-triazin-2(1H)-one; 4-Amino-1-beta-D-ribofuranosyl-1,3,5-traizin-2(1H)-one; 4-Amino-1-beta-D-ribofuranosyl-1,3,5-triazine-2(1H)-one; 4-Amino-1-beta-D-ribofuranosyl-s-triazin-2(1H)-one; 4-Amino-1-beta-d-ribofuranosyl-1,3,5-triazin-2(1H)-one; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triaz; 4-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,3,5-triazin-2-one; 4-amino-1-beta-L-ribofuranosyl-1,3,5-triazin-2(1H)-one; 5 AZC; 5 Azacytidine; 5-AC; 5-AZAC; 5-AZCR; 5-aza-CR; 5-azacitidine; 5-azacytidine; 5-azacytidine, Mylosar, Ladakamycin, Vidaza, Azacitidine; 5AzaC
Indication
Disease Entry ICD 11 Status REF
Acute myelogenous leukaemia 2A41 Approved [1]
Chronic myelomonocytic leukemia Approved [1]
Leukemia Approved [1]
Myelodysplastic syndrome 2A37 Approved [2]
Myeloproliferative neoplasm 2A20 Approved [1]
Plasma cell myeloma 2A83.1 Approved [1]
Therapeutic Class
Anticancer Agents
Cross-matching ID
PubChem CID
9444
ChEBI ID
CHEBI:2038
CAS Number
CAS 320-67-2
TTD Drug ID
DMTA5OE
VARIDT Drug ID
DR00983
INTEDE Drug ID
DR0163

Molecule-Related Drug Atlas

Molecule-Related Drug Atlas
Molecule Type:
DTT
DME
DOT
Drug Status:
Clinical Trial Drug(s)
Patented Agent(s)
Investigative Drug(s)
Approved Drug(s)
Preclinical Drug(s)
Download the Complete Related Drug List
Drug(s) Targeting DNA [cytosine-5]-methyltransferase (DNMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Curcumin DMQPH29 Solid tumour/cancer 2A00-2F9Z Phase 3 [10]
S-110 DMXY34J Acute myeloid leukaemia 2A60 Phase 3 [11]
ASTX727 DM4HK8Z Chronic myelogenous leukaemia 2A20.0 Phase 3 [12]
PMID27376512-Compound-PG-11047 DM5K4YF N. A. N. A. Patented [13]
PMID27376512-Compound-PG-11048 DM3U7RN N. A. N. A. Patented [13]
PMID27376512-Compound-MTC-434 DM70CTE N. A. N. A. Patented [13]
PMID27376512-Compound-CROs DMBFUTL N. A. N. A. Patented [13]
(L-)-S-adenosyl-L-homocysteine DMDUN83 Discovery agent N.A. Investigative [14]
NSC-622445 DME35CB Discovery agent N.A. Investigative [10]
NSC-622444 DMM5UT9 Discovery agent N.A. Investigative [10]
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Drug(s) Metabolized By Cytidine aminohydrolase (CDA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [15]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [16]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [17]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [18]
Drug(s) Metabolized By Cytidine deaminase (cdd)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [5]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [5]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [5]
Drug(s) Affected By Bcl-2-like protein 1 (BCL2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [19]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [20]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Selenium DM25CGV N. A. N. A. Approved [22]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [23]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [25]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [26]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [28]
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Drug(s) Affected By Cytochrome P450 1A1 (CYP1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [29]
Riluzole DMECBWN Amyotrophic lateral sclerosis 8B60.0 Approved [30]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [31]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [32]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [33]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [28]
Ethacrynic acid DM60QMR Edema MG29 Approved [34]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [35]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [36]
Clofibrate DMPC1J7 Dysbetalipoproteinemia 5C80.2 Approved [37]
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Drug(s) Affected By Cytochrome P450 1A2 (CYP1A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zolmitriptan DM1IB4Q Migraine 8A80 Approved [38]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [38]
Etoricoxib DM6A4NW Rheumatoid arthritis FA20 Approved [38]
Capsaicin DMGMF6V Back pain ME84.Z Approved [39]
Hesperetin DMKER83 High blood cholesterol level 5C80.00 Approved [40]
Stiripentol DMMSDOY Dravet syndrome 8A61.11 Approved [41]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [42]
Zileuton DMVRIC2 Allergic asthma CA23.0 Approved [43]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [44]
Clonidine DM6RZ9Q Attention deficit hyperactivity disorder 6A05.Z Approved [45]
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Drug(s) Affected By Aryl hydrocarbon receptor (AHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [47]
Citalopram DM2G9AE Acute coronary syndrome BA41 Approved [48]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [49]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [50]
Quercetin DM3NC4M Obesity 5B81 Approved [51]
Omeprazole DM471KJ Cystic fibrosis CA25 Approved [52]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [54]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [55]
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Drug(s) Affected By Cytochrome P450 1B1 (CYP1B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [30]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [57]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [58]
Estrone DM5T6US Acne vulgaris ED80 Approved [59]
Melatonin DMKWFBT Depression 6A70-6A7Z Approved [60]
Vitamin A DMJ2AH4 Night blindness 9D45 Approved [61]
Amodiaquine DME4RA8 Malaria 1F40-1F45 Approved [62]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [63]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [64]
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Drug(s) Affected By Sulfotransferase 1C2 (SULT1C2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [70]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [74]
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Drug(s) Affected By Phospholipid phosphatase 1 (PLPP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [80]
Paclitaxel DMLB81S Breast carcinoma Approved [81]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [81]
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Drug(s) Affected By Tectonin beta-propeller repeat-containing protein 2 (TECPR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [84]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [85]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
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Drug(s) Affected By TBC1 domain family member 4 (TBC1D4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [92]
Vinblastine DM5TVS3 Advanced cancer 2A00-2F9Z Approved [80]
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Drug(s) Affected By Multiple epidermal growth factor-like domains protein 6 (MEGF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
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Drug(s) Affected By Stanniocalcin-2 (STC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [98]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [100]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [101]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [102]
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Drug(s) Affected By Integrin beta-2 (ITGB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [103]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [107]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [108]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
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Drug(s) Affected By Protein S100-A9 (S100A9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Primidone DM0WX6I Epilepsy 8A60-8A68 Approved [109]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [114]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [116]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
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Drug(s) Affected By Receptor-type tyrosine-protein phosphatase C (PTPRC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [117]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [118]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [119]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [121]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [124]
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Drug(s) Affected By Delta-aminolevulinic acid dehydratase (ALAD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Estrone DM5T6US Acne vulgaris ED80 Approved [125]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [127]
Mestranol DMG3F94 Contraception QA21 Approved [125]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [125]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [128]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [129]
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Drug(s) Affected By Hepatocyte growth factor (HGF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [131]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [133]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [133]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [134]
Etodolac DM6WJO9 Osteoarthritis FA00-FA05 Approved [135]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [136]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
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Drug(s) Affected By Heat shock 70 kDa protein 6 (HSPA6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [101]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [139]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [140]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [141]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [35]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
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Drug(s) Affected By Gamma-aminobutyric acid receptor subunit beta-1 (GABRB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [142]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Folic Acid DMEMBJC Colorectal carcinoma Approved [143]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [144]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
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Drug(s) Affected By Transcription factor E3 (TFE3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [148]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [149]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [149]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
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Drug(s) Affected By Pro-thyrotropin-releasing hormone (TRH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethanol DMDRQZU Chronic pain MG30 Approved [151]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [154]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
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Drug(s) Affected By Protein S100-P (S100P)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [155]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [158]
Estrone DM5T6US Acne vulgaris ED80 Approved [159]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Adenosine triphosphate DM79F6G Malnutrition 5B50-5B71 Approved [161]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
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Drug(s) Affected By Protein PML (PML)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [162]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [132]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Menthol DMG2KW7 Back pain ME84.Z Approved [164]
Mitoxantrone DMM39BF Acute myelogenous leukaemia 2A41 Approved [165]
Epirubicin DMPDW6T Solid tumour/cancer 2A00-2F9Z Approved [165]
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Drug(s) Affected By DNA-binding protein inhibitor ID-1 (ID1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [166]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [64]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [168]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
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Drug(s) Affected By Cyclin-dependent kinase 4 inhibitor B (CDKN2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Gefitinib DM15F0X Colon adenocarcinoma Approved [171]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Prednisone DM2HG4X Acute asthma CA23 Approved [172]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [173]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [174]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By LIM and senescent cell antigen-like-containing domain protein 1 (LIMS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Bortezomib DMNO38U Leukemia Approved [176]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 SUMO-protein ligase RanBP2 (RANBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Arsenic DMTL2Y1 N. A. N. A. Approved [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 1C (CDKN1C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [22]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [180]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related protein Rab-13 (RAB13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
Topotecan DMP6G8T Central nervous system neoplasm Approved [80]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
SB-431542 DM0YOXQ Pulmonary fibrosis CB03.4 Preclinical [183]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [184]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lysozyme C (LYZ)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Glibenclamide DM8JXPZ Diabetic complication 5A2Y Approved [188]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [189]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [150]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [190]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-10 (CLDN10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [192]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [129]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [129]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [194]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sushi repeat-containing protein SRPX (SRPX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [195]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [196]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein delta homolog 1 (DLK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [197]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [198]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [129]
Indomethacin DMSC4A7 Bursitis Approved [199]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA-binding protein inhibitor ID-3 (ID3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [64]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [200]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [201]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [202]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Collagen alpha-1(XIV) chain (COL14A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [204]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethanol DMDRQZU Chronic pain MG30 Approved [151]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Equilibrative nucleoside transporter 2 (SLC29A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [206]
Uridine DMQTREB Depression 6A70-6A7Z Approved [207]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytohesin-1 (CYTH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [211]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By C3a anaphylatoxin chemotactic receptor (C3AR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [212]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [181]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [84]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Sulforaphane DMQY3L0 Skin disease EA00-EM0Z Investigative [213]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA dC->dU-editing enzyme APOBEC-3F (APOBEC3F)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [214]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Angiogenic factor with G patch and FHA domains 1 (AGGF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [216]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase Praja-1 (PJA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [22]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-10 (CASP10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [218]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [219]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [220]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tetraspanin-32 (TSPAN32)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [221]
Mivebresib DMCPF90 Acute myeloid leukaemia 2A60 Phase 1 [222]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
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Drug(s) Affected By Tribbles homolog 1 (TRIB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Lipopolysaccharide-induced tumor necrosis factor-alpha factor (LITAF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Menthol DMG2KW7 Back pain ME84.Z Approved [164]
Mecamylamine DMGQFYB Essential hypertension BA00 Approved [224]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha (PIP5K1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [190]
Bortezomib DMNO38U Leukemia Approved [176]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [226]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Centromere protein O (CENPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [144]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [228]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
GSK2110183 DMZHB37 leukaemia 2A60-2B33 Phase 2 [229]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [230]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Iron-sulfur cluster assembly 1 homolog, mitochondrial (ISCA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Bortezomib DMNO38U Leukemia Approved [176]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [22]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase TRIM8 (TRIM8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Panobinostat DM58WKG Chronic graft versus host disease Approved [232]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Uncharacterized protein C6orf62 (C6ORF62)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [126]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Bortezomib DMNO38U Leukemia Approved [176]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [234]
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metal transporter CNNM2 (CNNM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [228]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [235]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [190]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pantothenate kinase 3 (PANK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [237]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [238]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA dC->dU-editing enzyme APOBEC-3G (APOBEC3G)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Bortezomib DMNO38U Leukemia Approved [176]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [214]
Isoflavone DM7U58J N. A. N. A. Phase 4 [239]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [221]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuritin (NRN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Arsenic DMTL2Y1 N. A. N. A. Approved [179]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [89]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By NTF2-related export protein 2 (NXT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [240]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By THUMP domain-containing protein 1 (THUMPD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [241]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [242]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [243]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [244]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protein FAM8A1 (FAM8A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [181]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [84]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
Milchsaure DM462BT Pruritus EC90 Investigative [245]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [246]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Methionine-R-sulfoxide reductase B2, mitochondrial (MSRB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [247]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [235]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mitotic spindle assembly checkpoint protein MAD1 (MAD1L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [248]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [249]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [57]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Signal-regulatory protein beta-1 (SIRPB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [250]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Syntenin-1 (SDCBP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [251]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Benzatropine DMF7EXL Parkinsonian disorder Approved [253]
Clozapine DMFC71L Schizophrenia 6A20 Approved [253]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Complexin-1 (CPLX1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [254]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Nephrocystin-1 (NPHP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [244]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Phosphatase and actin regulator 2 (PHACTR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [92]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nuclear factor of activated T-cells, cytoplasmic 1 (NFATC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [255]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [256]
Menthol DMG2KW7 Back pain ME84.Z Approved [164]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [257]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Hydroxychloroquine DMSIVND Chronic renal failure GB61.Z Approved [258]
Arsenic DMTL2Y1 N. A. N. A. Approved [259]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [260]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Acyl-CoA 6-desaturase (FADS2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluoxetine DM3PD2C Bipolar depression Approved [237]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [261]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [262]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [263]
Bortezomib DMNO38U Leukemia Approved [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Metalloproteinase inhibitor 1 (TIMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Pentoxifylline DMU3DNC Alcoholic hepatitis DB94.1 Approved [45]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [264]
Verapamil DMA7PEW Angina pectoris BA40 Approved [265]
Selenium DM25CGV N. A. N. A. Approved [266]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [265]
Quercetin DM3NC4M Obesity 5B81 Approved [267]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [219]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [268]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [269]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cystatin-C (CST3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [247]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [270]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [271]
Gentamicin DMKINJO Bacteremia 1A73 Approved [272]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cystatin-S (CST4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [273]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [89]
Drug(s) Affected By Interstitial collagenase (MMP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [274]
Etretinate DM2CZFA Keratosis ED56 Approved [275]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [276]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [277]
Quercetin DM3NC4M Obesity 5B81 Approved [278]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [279]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [280]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Integrin beta-1 (ITGB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [282]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Methotrexate DM2TEOL Anterior urethra cancer Approved [283]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Fructose DM43AN2 Vomiting MD90 Approved [284]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [285]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [286]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type II cytoskeletal 8 (KRT8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Selenium DM25CGV N. A. N. A. Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [287]
Quercetin DM3NC4M Obesity 5B81 Approved [288]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [191]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [290]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurofilament light polypeptide (NEFL)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [291]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [112]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein disulfide-isomerase (P4HB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [292]
Etretinate DM2CZFA Keratosis ED56 Approved [293]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [292]
Quercetin DM3NC4M Obesity 5B81 Approved [294]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [219]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [292]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [295]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [292]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Decorin (DCN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [296]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [297]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Folic Acid DMEMBJC Colorectal carcinoma Approved [298]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Profilin-1 (PFN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Selenium DM25CGV N. A. N. A. Approved [22]
Etretinate DM2CZFA Keratosis ED56 Approved [293]
Quercetin DM3NC4M Obesity 5B81 Approved [299]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [300]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [148]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [301]
Haloperidol DM96SE0 Delirium Approved [253]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [302]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Proto-oncogene tyrosine-protein kinase receptor Ret (RET)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [265]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [265]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Irbesartan DMTP1DC Diabetic kidney disease GB61.Z Approved [303]
Estrone DM5T6US Acne vulgaris ED80 Approved [125]
Methazolamide DM7J2TA Glaucoma/ocular hypertension 9C61 Approved [265]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [304]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tropomyosin beta chain (TPM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Benzatropine DMF7EXL Parkinsonian disorder Approved [253]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [271]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor Sp1 (SP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fructose DM43AN2 Vomiting MD90 Approved [45]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [305]
Quercetin DM3NC4M Obesity 5B81 Approved [306]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [307]
Penicillamine DM40EF6 Cystinuria 5C60.2 Approved [308]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [309]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [305]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [310]
Plicamycin DM7C8YV Hypercalcaemia 5B91.0 Approved [311]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cytoskeletal 19 (KRT19)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-like growth factor-binding protein 1 (IGFBP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [46]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [312]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Lisinopril DMUOK4C Chronic heart failure BD1Z Approved [313]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [314]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein uS2 (RPSA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Quercetin DM3NC4M Obesity 5B81 Approved [294]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [315]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [316]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [317]
Dopamine DMPGUCF Acromegaly 5A60.0 Approved [318]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [319]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Glycodelin (PAEP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [270]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [320]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [211]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 SUMO-protein ligase EGR2 (EGR2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pregnancy-specific beta-1-glycoprotein 1 (PSG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
PEITC DMOMN31 Prostate cancer 2C82.0 Phase 2 [323]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Collagen alpha-3(VI) chain (COL6A3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [324]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [209]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [325]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Parathyroid hormone-related protein (PTHLH)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Ceruletide DM2WE5K Caerulein stimulated gastric and pancreatic secretion 5A4Y Approved [326]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [327]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Testosterone DM7HUNW Hot flushes GA30 Approved [328]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [185]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plastin-3 (PLS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Haloperidol DM96SE0 Delirium Approved [253]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Clozapine DMFC71L Schizophrenia 6A20 Approved [253]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [329]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
Arsenic DMTL2Y1 N. A. N. A. Approved [179]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial (MTHFD2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [98]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [330]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [330]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Lindane DMB8CNL Infestations of lice and scabies 1G00.Z Approved [330]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Pyruvate kinase PKM (PKM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Selenium DM25CGV N. A. N. A. Approved [22]
Epinephrine DM3KJBC Acute asthma CA23 Approved [331]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [332]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [333]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [290]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [302]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Carboxypeptidase E (CPE)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethanol DMDRQZU Chronic pain MG30 Approved [334]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [236]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High mobility group protein HMG-I/HMG-Y (HMGA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [335]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Ethanol DMDRQZU Chronic pain MG30 Approved [336]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Methamphetamine DMPM4SK Anxiety Approved [337]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gap junction alpha-1 protein (GJA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [338]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [339]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Folic Acid DMEMBJC Colorectal carcinoma Approved [340]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [196]
Letrozole DMH07Y3 Estrogen-receptor positive breast cancer Approved [338]
Carvedilol DMHTEAO Chronic heart failure BD1Z Approved [341]
Flutamide DMK0O7U Prostate cancer 2C82.0 Approved [342]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Desmin (DES)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Selenium DM25CGV N. A. N. A. Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [343]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [344]
Artesunate DMR27C8 Infection of P. falciparum 1F40 Approved [345]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [346]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [347]
Zalcitabine DMH7MUV Human immunodeficiency virus infection 1C62 Approved [45]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Plasma membrane calcium-transporting ATPase 1 (ATP2B1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [286]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [250]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [348]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A2 (CCNA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [349]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [350]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [352]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [353]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [355]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 5'-nucleotidase (NT5E)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Quercetin DM3NC4M Obesity 5B81 Approved [356]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibroblast growth factor 7 (FGF7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [357]
Methotrexate DM2TEOL Anterior urethra cancer Approved [203]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [324]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [137]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [203]
Nifedipine DMSVOZT Angina pectoris BA40 Approved [358]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [359]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Insulin-like growth factor-binding protein 4 (IGFBP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [97]
Selenium DM25CGV N. A. N. A. Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [360]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [361]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription elongation factor A protein 1 (TCEA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [362]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D1 (CCND1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [363]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [364]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [365]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [366]
Gefitinib DM15F0X Colon adenocarcinoma Approved [367]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [368]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [369]
Selenium DM25CGV N. A. N. A. Approved [22]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [370]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [371]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tenascin (TNC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Diazepam DM08E9O Alcohol withdrawal Approved [372]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [132]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [373]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [241]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [270]
Capsaicin DMGMF6V Back pain ME84.Z Approved [374]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By V-type proton ATPase 16 kDa proteolipid subunit c (ATP6V0C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [375]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [211]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [376]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [377]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Protein ITPRID2 (ITPRID2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 1 (DUSP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [138]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [378]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [379]
Methotrexate DM2TEOL Anterior urethra cancer Approved [380]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [314]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [381]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-12 subunit beta (IL12B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [382]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [383]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [384]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [385]
Ergotidine DM78IME Osteoarthritis FA00-FA05 Approved [386]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [387]
Capsaicin DMGMF6V Back pain ME84.Z Approved [388]
Dinoprostone DMTYOPD Medical abortion JA00.1Z Approved [389]
Bryostatin-1 DM1JOXY Alzheimer disease 8A20 Phase 2 [390]
RGI-2001 DM4AC2F Graft-versus-host disease 4B24 Phase 2 [391]
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Drug(s) Affected By Neurotensin/neuromedin N (NTS)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [392]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [393]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [322]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [80]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [394]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [393]
phorbol 12-myristate 13-acetate DMJWD62 Acute myeloid leukaemia 2A60 Phase 2 [392]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanylate-binding protein 2 (GBP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By MHC class II transactivator (CIITA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Verapamil DMA7PEW Angina pectoris BA40 Approved [395]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [124]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [396]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [124]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [348]
Arsenic DMTL2Y1 N. A. N. A. Approved [397]
Ritonavir DMU764S Human immunodeficiency virus infection 1C62 Approved [396]
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Drug(s) Affected By Cyclin-dependent kinase inhibitor 1 (CDKN1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [398]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [357]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [282]
Gefitinib DM15F0X Colon adenocarcinoma Approved [399]
Talazoparib DM1KS78 Breast cancer 2C60-2C65 Approved [368]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [56]
Etretinate DM2CZFA Keratosis ED56 Approved [400]
Prednisone DM2HG4X Acute asthma CA23 Approved [172]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [401]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [201]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Exosome RNA helicase MTR4 (MTREX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [402]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [376]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [403]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [89]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [244]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-S1-casein (CSN1S1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Nuclear receptor-interacting protein 1 (NRIP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [46]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [404]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [250]
Teniposide DMLW57T Acute lymphoblastic leukaemia 2A85 Approved [405]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein Hox-A1 (HOXA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [406]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [199]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [80]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [407]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ectonucleoside triphosphate diphosphohydrolase 1 (ENTPD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [408]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [409]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [181]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [22]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ephrin-A3 (EFNA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [144]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [244]
KOJIC ACID DMP84CS Discovery agent N.A. Investigative [410]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1 (ART1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Uracil mustard DMHL7OB Acute myeloid leukaemia 2A60 Approved [45]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
Drug(s) Affected By Branched-chain-amino-acid aminotransferase, cytosolic (BCAT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [149]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [149]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microfibrillar-associated protein 2 (MFAP2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [112]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [112]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [411]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Laminin subunit beta-2 (LAMB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [412]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [413]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NHP2-like protein 1 (SNU13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [22]
DNCB DMDTVYC Immune System disease 4A01-4B41 Phase 2 [414]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PP-242 DM2348V Discovery agent N.A. Investigative [415]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [243]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein DLX-6 (DLX6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [270]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neurotrypsin (PRSS12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [333]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [317]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Arsenic DMTL2Y1 N. A. N. A. Approved [397]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Elongation factor 1-alpha 1 (EEF1A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Etretinate DM2CZFA Keratosis ED56 Approved [293]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [187]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [416]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [290]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [302]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Menthol DMG2KW7 Back pain ME84.Z Approved [164]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein 1A (MAP1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Haloperidol DM96SE0 Delirium Approved [253]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Clozapine DMFC71L Schizophrenia 6A20 Approved [253]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [417]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By E3 ubiquitin-protein ligase Mdm2 (MDM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Flucytosine DM13VTW Cryptococcal meningitis Approved [25]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [25]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [418]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [419]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [420]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [295]
Amifostine DM5FL14 Mucositis CA00 Approved [421]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome c oxidase subunit 6A2, mitochondrial (COX6A2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [344]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [347]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [211]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [71]
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Drug(s) Affected By cAMP-responsive element modulator (CREM)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Bortezomib DMNO38U Leukemia Approved [176]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [422]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caldesmon (CALD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [423]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [424]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Benzatropine DMF7EXL Parkinsonian disorder Approved [253]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By ATP-dependent RNA helicase A (DHX9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [425]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ursodeoxycholic acid DMCUT21 Cholelithiasis DC11 Approved [426]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Gemcitabine DMSE3I7 Anterior urethra cancer Approved [427]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [240]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase PAK 1 (PAK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Quercetin DM3NC4M Obesity 5B81 Approved [131]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [428]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity mitogen-activated protein kinase kinase 5 (MAP2K5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [148]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Hesperidin DMI5DW1 Vascular purpura 3B60 Approved [429]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [216]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [216]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chitotriosidase-1 (CHIT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [431]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Ras and Rab interactor 1 (RIN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [227]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [432]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [144]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [129]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Keratin, type I cuticular Ha2 (KRT32)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Semaphorin-3A (SEMA3A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [228]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [235]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras GTPase-activating protein 3 (RASA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [433]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [422]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [242]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [422]
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Drug(s) Affected By Mediator of DNA damage checkpoint protein 1 (MDC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [227]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Bortezomib DMNO38U Leukemia Approved [176]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane glycoprotein NMB (GPNMB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [157]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Mortality factor 4-like protein 2 (MORF4L2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [434]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [435]
COUMESTROL DM40TBU Discovery agent N.A. Investigative [436]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [437]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By kinase isozyme 1, mitochondrial (PDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [66]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ifosfamide DMCT3I8 Adult central nervous system germ cell tumor Approved [149]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [344]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [438]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase 38 (STK38)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [439]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein phosphatase 2A activator (PTPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [22]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [221]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [440]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Reticulocalbin-1 (RCN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Haloperidol DM96SE0 Delirium Approved [253]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [271]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Menadione DMSJDTY Vitamin K deficiency 5B59 Approved [75]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Olfactory receptor 8B8 (OR8B8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Leukotriene B4 receptor 1 (LTB4R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [300]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Diphenylpyraline DMW4X37 Allergic rhinitis CA08.0 Approved [260]
Tamibarotene DM3G74J T-cell leukaemia 2A90 Phase 3 [104]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
BRN-3548355 DM4KXT0 N. A. N. A. Investigative [441]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [89]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/arginine-rich splicing factor 7 (SRSF7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [186]
Selenium DM25CGV N. A. N. A. Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [442]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Clozapine DMFC71L Schizophrenia 6A20 Approved [253]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanylate kinase (GUK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Aspirin DM672AH Acute coronary syndrome BA41 Approved [148]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [221]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
chloropicrin DMSGBQA Discovery agent N.A. Investigative [443]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Filamin A-interacting protein 1-like (FILIP1L)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [444]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ampicillin DMHWE7P Acute epiglottitis Approved [66]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Nucleolar MIF4G domain-containing protein 1 (NOM1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [445]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [422]
Sodium phenylbutyrate DMXLBCQ Spinal muscular atrophy 8B61 Approved [446]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [227]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Opioid growth factor receptor-like protein 1 (OGFRL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [409]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein kinase MRCK alpha (CDC42BPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Irinotecan DMP6SC2 Adenocarcinoma 2D40 Approved [236]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Extracellular sulfatase Sulf-1 (SULF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [247]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [228]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-acetyllactosaminide beta-1,6-N-acetylglucosaminyl-transferase (GCNT2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Bortezomib DMNO38U Leukemia Approved [176]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Cytarabine DMZD5QR Acute lymphoblastic leukaemia 2A85 Approved [92]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxidation resistance protein 1 (OXR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [347]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [447]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-2,8-sialyltransferase 8B (ST8SIA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Panobinostat DM58WKG Chronic graft versus host disease Approved [232]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [448]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [232]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Type II iodothyronine deiodinase (DIO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Quercetin DM3NC4M Obesity 5B81 Approved [449]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [450]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [451]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [203]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Mifepristone DMGZQEF Cushing disease 5A70 Approved [196]
Ergocalciferol DMHO0AR Hypoparathyroidism 5A50 Approved [452]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G-patch domain and KOW motifs-containing protein (GPKOW)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [227]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Tocopherol DMBIJZ6 N. A. N. A. Phase 2 [22]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Rho guanine nucleotide exchange factor 2 (ARHGEF2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [423]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [167]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Mebendazole DMO14SG Ascariasis 1F62 Approved [453]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [216]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [129]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homogentisate 1,2-dioxygenase (HGD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [454]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [242]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Secretory carrier-associated membrane protein 4 (SCAMP4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Protein bicaudal D homolog 1 (BICD1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [235]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [455]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ankyrin repeat and SOCS box protein 2 (ASB2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [122]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [456]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Eyes absent homolog 1 (EYA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [457]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [457]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [457]
Nilotinib DM7HXWT Chronic myelogenous leukaemia 2A20.0 Approved [457]
Ramelteon DM7IW9J Insomnia 7A00-7A0Z Approved [457]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [457]
Dabigatran DMDI6R4 Stroke 8B20 Approved [457]
Abacavir DMMN36E Human immunodeficiency virus infection 1C62 Approved [457]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Bcl-2-like protein 13 (BCL2L13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [209]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [458]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
Duvelisib DM7USVA Follicular lymphoma 2A80 Phase 2 Trial [459]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [227]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [184]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By RNA helicase Mov10l1 (MOV10L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
Drug(s) Affected By Rac GTPase-activating protein 1 (RACGAP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [425]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [335]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [460]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Ras-related protein Rab-1B (RAB1B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [461]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [71]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Semaphorin-6C (SEMA6C)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [84]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Sentrin-specific protease 3 (SENP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [227]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Bortezomib DMNO38U Leukemia Approved [176]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [462]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [435]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Ribonuclease P protein subunit p21 (RPP21)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [463]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Protocadherin-18 (PCDH18)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Epigallocatechin gallate DMCGWBJ Hepatic fibrosis DB93.0 Phase 3 [464]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [465]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
Trichostatin A DM9C8NX Solid tumour/cancer 2A00-2F9Z Investigative [185]
⏷ Show the Full List of 9 Drug(s)
Drug(s) Affected By Protein S100-A14 (S100A14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [212]
Phenobarbital DMXZOCG Cluster headache 8A81.0 Approved [182]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [466]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tryptase gamma (TPSG1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Rho GTPase-activating protein 35 (ARHGAP35)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Folic Acid DMEMBJC Colorectal carcinoma Approved [467]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [190]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
PMID28870136-Compound-52 DMFDERP N. A. N. A. Patented [227]
COUMARIN DM0N8ZM Discovery agent N.A. Investigative [227]
3R14S-OCHRATOXIN A DM2KEW6 Discovery agent N.A. Investigative [468]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Neuroligin-3 (NLGN3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [469]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
PDX-101 DM6OC53 Plasma cell myeloma 2A83.1 Phase 2 [68]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28460551-Compound-2 DM4DOUB N. A. N. A. Patented [86]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Polycystin-2-like protein 1 (PKD2L1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [470]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [471]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [195]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [241]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [95]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytoplasmic phosphatidylinositol transfer protein 1 (PITPNC1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor SOX-13 (SOX13)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Afadin- and alpha-actinin-binding protein (SSX2IP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Piroxicam DMTK234 Osteoarthritis FA00-FA05 Approved [240]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Permethrin DMZ0Q1G Pediculus capitis infestation 1G00.0 Approved [329]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transmembrane emp24 domain-containing protein 3 (TMED3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [129]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [129]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [221]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 7 Drug(s)
Drug(s) Affected By Protocadherin beta-4 (PCDHB4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Protocadherin beta-14 (PCDHB14)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [442]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [68]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [145]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Adenylate kinase isoenzyme 5 (AK5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [228]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Methamphetamine DMPM4SK Anxiety Approved [472]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [473]
Afimoxifene DMFORDT Breast cancer 2C60-2C65 Phase 2 [448]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Albumin (ALB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Sulfamethoxazole DMB08GE Acute otitis media AB00 Approved [45]
Tolbutamide DM02AWV Advanced cancer 2A00-2F9Z Approved [474]
Diazepam DM08E9O Alcohol withdrawal Approved [475]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [476]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [477]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [478]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [479]
Methotrexate DM2TEOL Anterior urethra cancer Approved [480]
Quercetin DM3NC4M Obesity 5B81 Approved [481]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Alpha-fetoprotein (AFP)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [482]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [477]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [483]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Isoniazid DM5JVS3 Latent tuberculosis infection Approved [482]
Chlorpromazine DMBGZI3 Acute intermittent hepatic porphyria 5C58.11 Approved [314]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [484]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [271]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cytochrome P450 3A4 (CYP3A4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Eplerenone DMF0NQR Heart failure BD10-BD13 Approved [485]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [486]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [487]
Voriconazole DMAOL2S Aspergillosis 1F20 Approved [488]
Proguanil DMBL79I Malaria 1F40-1F45 Approved [489]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [489]
Loratadine DMF3AN7 Allergy 4A80-4A85 Approved [490]
Nelfinavir mesylate DMFX6G8 N. A. N. A. Approved [491]
Capsaicin DMGMF6V Back pain ME84.Z Approved [492]
Axitinib DMGVH6N Renal cell carcinoma 2C90 Approved [493]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine aminotransferase (TAT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Colchicine DM2POTE Acute gout flare FA25.0 Approved [494]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [495]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [496]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [497]
Miconazole DMPMYE8 Cutaneous candidiasis 1F23.14 Approved [498]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [458]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepatocyte nuclear factor 4-alpha (HNF4A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [499]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [477]
Fructose DM43AN2 Vomiting MD90 Approved [500]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [501]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [482]
SR141716A DMCO5JZ Obesity 5B81 Approved [502]
Bosentan DMIOGBU Pulmonary arterial hypertension BB01.0 Approved [496]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [503]
Estriol DMOEM2I Hormone deficiency 5A61.1 Approved [504]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By CCAAT/enhancer-binding protein alpha (CEBPA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [234]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [505]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [506]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [507]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [134]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [134]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [508]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hematopoietically-expressed homeobox protein HHEX (HHEX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [187]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [115]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [150]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Chenodiol DMQ8JIK Cholelithiasis DC11 Approved [509]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [80]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Suppressor of cytokine signaling 3 (SOCS3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [46]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [510]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [112]
Fedratinib DM4ZBK6 Myelofibrosis 2A20.2 Approved [511]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Pyrimethamine DM5X7VY Malaria 1F40-1F45 Approved [511]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [132]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Telomerase reverse transcriptase (TERT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [512]
Gefitinib DM15F0X Colon adenocarcinoma Approved [513]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [514]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [515]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [516]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [517]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [518]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [519]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Aquaporin-9 (AQP9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [520]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [79]
Cholecalciferol DMGU74E Adult acute monocytic leukemia Approved [521]
Arsenic DMTL2Y1 N. A. N. A. Approved [522]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Malathion DMXZ84M Pediculus capitis infestation 1G00.0 Approved [329]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [520]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-7 (GNG7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [270]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Niclosamide DMJAGXQ Cestodes infection 1F70-1F76 Approved [144]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [129]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [129]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [145]
Genistein DM0JETC Menopause symptom GA30.0 Phase 2/3 [523]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-7 (CLDN7)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [524]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Sodium lauryl sulfate DMLJ634 Constipation DD91.1 Approved [235]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-9 (CLDN9)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [524]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [422]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Myc proto-oncogene protein (MYC)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [525]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [138]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [351]
Gefitinib DM15F0X Colon adenocarcinoma Approved [171]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Selenium DM25CGV N. A. N. A. Approved [526]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [370]
Trametinib DM2JGQ3 Melanoma 2C30 Approved [527]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [528]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcitonin (CALCA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ranitidine DM0GUSX Gastric ulcer DA60 Approved [529]
Fructose DM43AN2 Vomiting MD90 Approved [284]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Nizatidine DMGFV3Z Acid-reflux disorder DA22 Approved [529]
Capsaicin DMGMF6V Back pain ME84.Z Approved [530]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor (TNF)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Indomethacin DMSC4A7 Bursitis Approved [531]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [532]
Fructose DM43AN2 Vomiting MD90 Approved [45]
Ketoprofen DMRKXPT Bursitis Approved [45]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [533]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [534]
Baclofen DM0QV1J Multiple sclerosis 8A40 Approved [535]
Gefitinib DM15F0X Colon adenocarcinoma Approved [536]
Ganciclovir DM1MBYQ Cytomegalovirus infection 1D82 Approved [537]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [296]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Estrogen receptor (ESR1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [538]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [366]
Gefitinib DM15F0X Colon adenocarcinoma Approved [539]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [540]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [541]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [542]
Quercetin DM3NC4M Obesity 5B81 Approved [543]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [544]
Procaine DM4LSNE Anaesthesia 9A78.6 Approved [540]
Estrone DM5T6US Acne vulgaris ED80 Approved [545]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cellular tumor antigen p53 (TP53)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [546]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [420]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [547]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [548]
Paclitaxel DMLB81S Breast carcinoma Approved [549]
Floxuridine DM04LR2 Colorectal cancer 2B91.Z Approved [550]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [19]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [551]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [552]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-4 (IL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [553]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [554]
Tolnaftate DM28MU7 Dermatophytosis 1F28.2 Approved [555]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [556]
Salicyclic acid DM2F8XZ Acne vulgaris ED80 Approved [557]
Prednisone DM2HG4X Acute asthma CA23 Approved [558]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [559]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [510]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [560]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 (IL6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [203]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [561]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Pantothenic acid DM091H2 Vitamin deficiency 5B55-5B71 Approved [64]
Indinavir DM0T3YH Human immunodeficiency virus infection 1C62 Approved [562]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [563]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [296]
Imiquimod DM1TMA3 Alopecia areata ED70.2 Approved [564]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [565]
Methotrexate DM2TEOL Anterior urethra cancer Approved [203]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tyrosine-protein kinase Fyn (FYN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [566]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [158]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ethanol DMDRQZU Chronic pain MG30 Approved [567]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [568]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [433]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 1 (CDK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [350]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [569]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [526]
Etretinate DM2CZFA Keratosis ED56 Approved [400]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [162]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [180]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By L-lactate dehydrogenase B chain (LDHB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [79]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [570]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [571]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Dihydroartemisinin DMBXVMZ Malaria 1F40-1F45 Approved [302]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Fenofibrate DMFKXDY Coronary atherosclerosis Approved [79]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thyroid peroxidase (TPO)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [572]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [573]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [574]
Propylthiouracil DM6D7N8 Hyperthyroidism 5A02 Approved [575]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [576]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Glutathione DMAHMT9 Human immunodeficiency virus infection 1C62 Approved [574]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [576]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Prostate-specific antigen (KLK3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [46]
Levonorgestrel DM1DP7T Atypical endometrial hyperplasia Approved [577]
Selenium DM25CGV N. A. N. A. Approved [578]
Quercetin DM3NC4M Obesity 5B81 Approved [579]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [580]
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [581]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [582]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [583]
Testosterone DM7HUNW Hot flushes GA30 Approved [584]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H1.0 (H1-0)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethanol DMDRQZU Chronic pain MG30 Approved [334]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Interleukin-6 receptor subunit alpha (IL6R)
Drug Name Drug ID Indication ICD 11 Highest Status REF
TECFIDERA DM2OVDT Multiple sclerosis 8A40 Approved [585]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [219]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [586]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [185]
Emetine DMCT2YF Hepatitis virus infection 1E50-1E51 Approved [587]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [588]
Azathioprine DMMZSXQ Lupus nephritis 4A40.0Y Approved [150]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Gamma-enolase (ENO2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [589]
Estrone DM5T6US Acne vulgaris ED80 Approved [159]
Aluminium DM6ECN9 Hyperhidrosis EE00 Approved [590]
LY2835219 DM93VBZ Breast cancer 2C60-2C65 Approved [591]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Androgen receptor (AR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Prasterone DM67VKL Chronic obstructive pulmonary disease CA22 Approved [592]
Nilutamide DMFN07X Prostate cancer 2C82.0 Approved [592]
Hydroxyflutamide DMGIZF5 Prostate cancer 2C82.0 Approved [592]
Enzalutamide DMGL19D Prostate cancer 2C82.0 Approved [593]
Bicalutamide DMZMSPF Prostate cancer 2C82.0 Approved [594]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [595]
Drospirenone DM1A9W3 Acne vulgaris ED80 Approved [596]
Nitrendipine DM21C09 Hypertension BA00-BA04 Approved [597]
Selenium DM25CGV N. A. N. A. Approved [578]
Spironolactone DM2AQ5N Chronic heart failure BD1Z Approved [598]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Microtubule-associated protein tau (MAPT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [599]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [600]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [378]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [601]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [602]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Chromogranin-A (CHGA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [603]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [190]
Ethinyl Estradiol DMODJ40 Acne vulgaris ED80 Approved [604]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [605]
Resveratrol DM3RWXL Giant cell arteritis 4A44.2 Phase 3 [606]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 4 (CDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Palbociclib DMD7L94 Breast cancer 2C60-2C65 Approved [607]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [608]
Selenium DM25CGV N. A. N. A. Approved [526]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [609]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [610]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [611]
Quercetin DM3NC4M Obesity 5B81 Approved [180]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cadherin-1 (CDH1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [612]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [613]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [614]
Liraglutide DM3FXPS Non-insulin dependent diabetes 5A11 Approved [542]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [615]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Polyethylene glycol DM4I1JP Constipation DD91.1 Approved [285]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G2/mitotic-specific cyclin-B1 (CCNB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [350]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [282]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [526]
Etretinate DM2CZFA Keratosis ED56 Approved [400]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [401]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [616]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [98]
Methotrexate DM2TEOL Anterior urethra cancer Approved [354]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By 15-hydroxyprostaglandin dehydrogenase (HPGD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Rofecoxib DM3P5DA Osteoarthritis FA00-FA05 Approved [132]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [321]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [617]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Flurbiprofen DMGN4BY Osteoarthritis FA00-FA05 Approved [617]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Histone H2AX (H2AX)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [618]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [619]
Selenium DM25CGV N. A. N. A. Approved [22]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [620]
Etretinate DM2CZFA Keratosis ED56 Approved [621]
Methotrexate DM2TEOL Anterior urethra cancer Approved [622]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [623]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [624]
Lapatinib DM3BH1Y Breast cancer 2C60-2C65 Approved [625]
Quercetin DM3NC4M Obesity 5B81 Approved [626]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Methylated-DNA--protein-cysteine methyltransferase (MGMT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [627]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [158]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [628]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Disulfiram DMCL2OK Alcohol dependence 6C40.2 Approved [629]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Dexamethasone DMMWZET Acute adrenal insufficiency Approved [630]
Phenytoin DMNOKBV Epilepsy 8A60-8A68 Approved [631]
Dacarbazine DMNPZL4 Adenocarcinoma 2D40 Approved [632]
Topotecan DMP6G8T Central nervous system neoplasm Approved [633]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Thyrotropin receptor (TSHR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [575]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [573]
Nevirapine DM6HX9B Human immunodeficiency virus infection 1C62 Approved [576]
Efavirenz DMC0GSJ Human immunodeficiency virus infection 1C62 Approved [576]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Folic Acid DMEMBJC Colorectal carcinoma Approved [121]
Vorinostat DMWMPD4 Adult acute monocytic leukemia Approved [634]
Nicotine DMWX5CO Lung cancer 2C25.0 Approved [635]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [636]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Hepatocyte nuclear factor 1-alpha (HNF1A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ethanol DMDRQZU Chronic pain MG30 Approved [637]
Diclofenac DMPIHLS Chronic renal failure GB61.Z Approved [216]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [638]
DTI-015 DMXZRW0 Brain cancer 2A00 Approved [211]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [216]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Fibulin-1 (FBLN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Selenium DM25CGV N. A. N. A. Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [203]
Methylprednisolone DM4BDON Acute adrenal insufficiency Approved [203]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [639]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Growth arrest and DNA damage-inducible protein GADD45 alpha (GADD45A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [101]
Sertraline DM0FB1J Coronary heart disease BA80.Z Approved [138]
Gefitinib DM15F0X Colon adenocarcinoma Approved [640]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [641]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [98]
Methotrexate DM2TEOL Anterior urethra cancer Approved [642]
Dactinomycin DM2YGNW Adult kidney Wilms tumor Approved [643]
Quercetin DM3NC4M Obesity 5B81 Approved [644]
Furazolidone DM3P6V7 Diarrhea ME05.1 Approved [645]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [646]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase 2 (CDK2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Mechlorethamine DM0CVXA Chronic myelogenous leukaemia 2A20.0 Approved [350]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [647]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [648]
Selenium DM25CGV N. A. N. A. Approved [526]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [401]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [649]
Methotrexate DM2TEOL Anterior urethra cancer Approved [650]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [610]
Quercetin DM3NC4M Obesity 5B81 Approved [180]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By DNA cytosine-5)-methyltransferase 1 (DNMT1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [569]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [651]
Cladribine DM3JDRP Hairy cell leukaemia 2A82.2 Approved [652]
Quercetin DM3NC4M Obesity 5B81 Approved [653]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [654]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [655]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [656]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [657]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [658]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By G1/S-specific cyclin-D2 (CCND2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Selenium DM25CGV N. A. N. A. Approved [526]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [180]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [659]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [660]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [398]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [661]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Oxytocin receptor (OXTR)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [225]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [436]
Progesterone DMUY35B Amenorrhea GA20.0 Approved [346]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-3 (CASP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Sevoflurane DMC9O43 Anaesthesia 9A78.6 Approved [662]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [663]
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [664]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [548]
Docetaxel DMDI269 Advanced cancer 2A00-2F9Z Approved [665]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [666]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [667]
Mannitol DMSCDY9 Bronchiectasis CA24 Approved [668]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [669]
Aprepitant DM053KT Depression 6A70-6A7Z Approved [670]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-dependent kinase inhibitor 2A (CDKN2A)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [170]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Prednisone DM2HG4X Acute asthma CA23 Approved [172]
Thioridazine DM35M8J Schizophrenia 6A20 Approved [611]
Quercetin DM3NC4M Obesity 5B81 Approved [27]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [202]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [420]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [671]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [672]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [673]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Melanoma-associated antigen 1 (MAGEA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Vemurafenib DM62UG5 Melanoma 2C30 Approved [674]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [675]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [676]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Melanoma-associated antigen 3 (MAGEA3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Clorgyline DMCEUJD Parkinson disease 8A00.0 Approved [404]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [677]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [376]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Killer cell immunoglobulin-like receptor 2DL1 (KIR2DL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [176]
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Drug(s) Affected By Killer cell immunoglobulin-like receptor 2DL2 (KIR2DL2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Drug(s) Affected By Killer cell immunoglobulin-like receptor 2DL3 (KIR2DL3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [66]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
PMID28870136-Compound-48 DMPIM9L N. A. N. A. Patented [126]
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [678]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By Killer cell immunoglobulin-like receptor 3DL1 (KIR3DL1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [679]
Drug(s) Affected By Killer cell immunoglobulin-like receptor 2DS4 (KIR2DS4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Bortezomib DMNO38U Leukemia Approved [176]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [636]
bisphenol A DM2ZLD7 Discovery agent N.A. Investigative [93]
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 6 (FASLG)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [93]
Gefitinib DM15F0X Colon adenocarcinoma Approved [680]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [681]
Epinephrine DM3KJBC Acute asthma CA23 Approved [682]
Quercetin DM3NC4M Obesity 5B81 Approved [683]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [28]
Fructose DM43AN2 Vomiting MD90 Approved [284]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [684]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [685]
Rifampicin DM5DSFZ Non-insulin dependent diabetes 5A11 Approved [686]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Stromal cell-derived factor 1 (CXCL12)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [687]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [105]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Estrone DM5T6US Acne vulgaris ED80 Approved [125]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [688]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Propofol DMB4OLE Anaesthesia 9A78.6 Approved [689]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tuberin (TSC2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Selenium DM25CGV N. A. N. A. Approved [22]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
Quercetin DM3NC4M Obesity 5B81 Approved [180]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [690]
Methamphetamine DMPM4SK Anxiety Approved [691]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [692]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tumor necrosis factor ligand superfamily member 10 (TNFSF10)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Bepridil DM0RKS4 Chronic/stable angina BA40.1 Approved [693]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [191]
Selenium DM25CGV N. A. N. A. Approved [22]
Ribavirin DMEYLH9 Hepatitis C virus infection 1E51.1 Approved [694]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [695]
Methotrexate DM2TEOL Anterior urethra cancer Approved [650]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [28]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [248]
Isotretinoin DM4QTBN Acne vulgaris ED80 Approved [696]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By High mobility group protein HMGI-C (HMGA2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [357]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Demecolcine DMCZQGK Solid tumour/cancer 2A00-2F9Z Approved [89]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Dasatinib DMJV2EK Blast phase chronic myelogenous leukemia, BCR-ABL1 positive Approved [228]
Melphalan DMOLNHF Hematologic disease 3C0Z Approved [348]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [433]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein Nkx-2.5 (NKX2-5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [433]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [84]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
AHPN DM8G6O4 Discovery agent N.A. Investigative [697]
⏷ Show the Full List of 8 Drug(s)
Drug(s) Affected By Death-associated protein kinase 1 (DAPK1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [603]
Menthol DMG2KW7 Back pain ME84.Z Approved [164]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [698]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [699]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-6 (CLDN6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [524]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [194]
Carbamazepine DMZOLBI Epilepsy 8A60-8A68 Approved [78]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [700]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
SNDX-275 DMH7W9X Breast cancer 2C60-2C65 Phase 3 [68]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [254]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Claudin-8 (CLDN8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Leuprorelin acetate DM15HAT Prostate cancer 2C82.0 Approved [701]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [524]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Testosterone DM7HUNW Hot flushes GA30 Approved [94]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [94]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [702]
Tetracycline DMZA017 Acne vulgaris ED80 Approved [194]
Dihydrotestosterone DM3S8XC Prostate hyperplasia GA90 Phase 4 [242]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Small ribosomal subunit protein eS6 (RPS6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [703]
Methotrexate DM2TEOL Anterior urethra cancer Approved [65]
Crizotinib DM4F29C Non-small-cell lung cancer 2C25.Y Approved [704]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [705]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [289]
Aspirin DM672AH Acute coronary syndrome BA41 Approved [706]
Testosterone DM7HUNW Hot flushes GA30 Approved [707]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [708]
Capivasertib DM9SKW8 Breast cancer 2C60-2C65 Approved [709]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform (PPP2CA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [378]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [710]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [711]
Imatinib DM7RJXL Acute lymphoblastic leukaemia 2A85 Approved [712]
Pioglitazone DMKJ485 Amyotrophic lateral sclerosis 8B60.0 Approved [713]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Daunorubicin DMQUSBT Acute monocytic leukemia Approved [714]
Cocaine DMSOX7I Anaesthesia 9A78.6 Approved [246]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [715]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-A1 (CCNA1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [113]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [251]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [113]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Acocantherin DM7JT24 Atrial fibrillation BC81.3 Approved [716]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [251]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [241]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Folic Acid DMEMBJC Colorectal carcinoma Approved [193]
Atropine DMEN6X7 Organophosphate poisoning NE6Z Approved [717]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Heat shock factor protein 1 (HSF1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [718]
SPI-1005 DM6XFHS Reperfusion injury ND56.Z Approved [719]
Imipramine DM2NUH3 Depression 6A70-6A7Z Approved [719]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [720]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [721]
Ceftazidime DM41GRA Bacteremia 1A73 Approved [719]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Chlorpheniramine DM5URA2 Allergic rhinitis CA08.0 Approved [719]
Ethacrynic acid DM60QMR Edema MG29 Approved [719]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [719]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor p65 (RELA)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Beta-carotene DM0RXBT Vitamin deficiency 5B55-5B71 Approved [365]
Selenium DM25CGV N. A. N. A. Approved [22]
Sulindac DM2QHZU Acute myelogenous leukaemia 2A41 Approved [162]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [722]
Deoxycholic acid DM3GYAL Subcutaneous fat disorder EF02 Approved [723]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [724]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [104]
Glucosamine DM4ZLFD Osteoarthritis FA00-FA05 Approved [725]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Tight junction protein ZO-1 (TJP1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [726]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Ethanol DMDRQZU Chronic pain MG30 Approved [727]
Hydrocortisone DMGEMB7 Acne vulgaris ED80 Approved [728]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dihydropyrimidine dehydrogenase (DPYD)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fluorouracil DMUM7HZ Adenocarcinoma 2D40 Approved [729]
Capecitabine DMTS85L Adenocarcinoma 2D40 Approved [730]
Tegafur DM31ZQM Solid tumour/cancer 2A00-2F9Z Approved [731]
Flucytosine DM13VTW Cryptococcal meningitis Approved [45]
Selenium DM25CGV N. A. N. A. Approved [22]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [219]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [76]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By BCL2/adenovirus E1B 19 kDa protein-interacting protein 3 (BNIP3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [130]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Acetic Acid, Glacial DM4SJ5Y infection in the ear canal AA0Y Approved [295]
Quinolones DM5GVHU Bacterial infection 1A00-1C4Z Approved [732]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [733]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [734]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By N-myc-interactor (NMI)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [248]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [735]
Triclosan DMZUR4N Malaria 1F40-1F45 Approved [153]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By NAD(P) transhydrogenase, mitochondrial (NNT)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [217]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Clozapine DMFC71L Schizophrenia 6A20 Approved [253]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [736]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Runt-related transcription factor 3 (RUNX3)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [737]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [256]
Gentamicin DMKINJO Bacteremia 1A73 Approved [737]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [568]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [737]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [737]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Mitomycin DMH0ZJE Breast cancer 2C60-2C65 Approved [738]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Caspase-8 (CASP8)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Lovastatin DM9OZWQ Arteriosclerosis BD40 Approved [739]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [740]
Etoposide DMNH3PG Acute myelogenous leukaemia 2A41 Approved [741]
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [281]
Gefitinib DM15F0X Colon adenocarcinoma Approved [680]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [742]
Nitric Oxide DM1RBYG Hypertension BA00-BA04 Approved [21]
Selenium DM25CGV N. A. N. A. Approved [22]
Ciprofloxacin XR DM2NLS9 Acute gonococcal cervicitis Approved [743]
Methotrexate DM2TEOL Anterior urethra cancer Approved [110]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Cyclin-G2 (CCNG2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Fulvestrant DM0YZC6 Breast cancer 2C60-2C65 Approved [125]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Fluoxetine DM3PD2C Bipolar depression Approved [330]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Estrone DM5T6US Acne vulgaris ED80 Approved [125]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [106]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
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Drug(s) Affected By Occludin (OCLN)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [744]
Methotrexate DM2TEOL Anterior urethra cancer Approved [745]
Quercetin DM3NC4M Obesity 5B81 Approved [746]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [147]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [747]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Thioguanine DM7NKEV Acute lymphocytic leukaemia 2B33.3 Approved [748]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Ethanol DMDRQZU Chronic pain MG30 Approved [727]
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Drug(s) Affected By kinase isozyme 4, mitochondrial (PDK4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [156]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [749]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [750]
Liothyronine DM6IR3P Congenital hypothyroidism Approved [751]
Ibuprofen DM8VCBE Dysmenorrhea GA34.3 Approved [149]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Testosterone enanthate DMB6871 N. A. N. A. Approved [175]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Dual specificity protein phosphatase 6 (DUSP6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [75]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
obeticholic acid DM3Q1SM Primary biliary cholangitis DB96.1 Approved [219]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [197]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [752]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [87]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
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Drug(s) Affected By Ribonucleoside-diphosphate reductase subunit M2 B (RRM2B)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methotrexate DM2TEOL Anterior urethra cancer Approved [24]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [753]
Cyclophosphamide DM4O2Z7 Advanced cancer 2A00-2F9Z Approved [753]
Marinol DM70IK5 Anorexia nervosa cachexia 6B80 Approved [169]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Clodronate DM9Y6X7 Hypercalcaemia 5B91.0 Approved [149]
Cidofovir DMA13GD Cytomegalovirus infection 1D82 Approved [149]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/iodide cotransporter (SLC5A5)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Methimazole DM25FL8 Hyperthyroidism 5A02 Approved [575]
Quercetin DM3NC4M Obesity 5B81 Approved [754]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [755]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [756]
Tazarotene DM8SMD1 Acne vulgaris ED80 Approved [757]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [757]
Alitretinoin DMME8LH Kaposi sarcoma 2B57 Approved [757]
Amiodarone DMUTEX3 Tachyarrhythmias BC71 Approved [758]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [759]
Romidepsin DMT5GNL Cutaneous T-cell lymphoma 2B01 Approved [757]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Krueppel-like factor 6 (KLF6)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Cannabidiol DM0659E Dravet syndrome 8A61.11 Approved [96]
Hydrogen peroxide DM1NG5W Infectious disease 1A00-CA43.1 Approved [760]
Selenium DM25CGV N. A. N. A. Approved [22]
Colchicine DM2POTE Acute gout flare FA25.0 Approved [201]
Simvastatin DM30SGU Arteriosclerosis BD40 Approved [111]
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Troglitazone DM3VFPD Diabetic complication 5A2Y Approved [99]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Leflunomide DMR8ONJ Arthritis FA20 Approved [77]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Killer cell immunoglobulin-like receptor 2DL4 (KIR2DL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Arsenic DMTL2Y1 N. A. N. A. Approved [231]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
QUERCITRIN DM1DH96 Discovery agent N.A. Investigative [678]
Drug(s) Affected By Protein Niban 1 (NIBAN1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [761]
Hydroquinone DM6AVR4 Melasma ED60.1 Approved [160]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [223]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [762]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [252]
Ivermectin DMDBX5F Intestinal strongyloidiasis due to nematode parasite 1F6B Approved [163]
Ethanol DMDRQZU Chronic pain MG30 Approved [334]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Calcium homeostasis modulator protein 2 (CALHM2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Selenium DM25CGV N. A. N. A. Approved [22]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [78]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Arsenic DMTL2Y1 N. A. N. A. Approved [83]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
Doxorubicin DMVP5YE Acute myelogenous leukaemia 2A41 Approved [152]
(+)-JQ1 DM1CZSJ Testicular cancer 2C80 Phase 1 [221]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Homeobox protein SIX2 (SIX2)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Arsenic trioxide DM61TA4 Acute lymphoblastic leukaemia 2A85 Approved [69]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [430]
Benzo(a)pyrene DMN7J43 N. A. N. A. Phase 1 [146]
Formaldehyde DM7Q6M0 Discovery agent N.A. Investigative [437]
⏷ Show the Full List of 6 Drug(s)
Drug(s) Affected By 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Quercetin DM3NC4M Obesity 5B81 Approved [66]
Tretinoin DM49DUI Acne vulgaris ED80 Approved [53]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Diethylstilbestrol DMN3UXQ Gonorrheal vaginitis GA02 Approved [763]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Methamphetamine DMPM4SK Anxiety Approved [764]
Amphotericin B DMTAJQE Acne vulgaris ED80 Approved [765]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [205]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sal-like protein 4 (SALL4)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [67]
Lenalidomide DM6Q7U4 Adult T-cell leukemia/lymphoma Approved [766]
Thalidomide DM70BU5 Adult T-cell leukemia/lymphoma Approved [766]
Testosterone DM7HUNW Hot flushes GA30 Approved [177]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [88]
Pomalidomide DMTGBAX Plasma cell myeloma 2A83.1 Approved [766]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [123]
Estradiol DMUNTE3 Acne vulgaris ED80 Approved [436]
TAK-243 DM4GKV2 Solid tumour/cancer 2A00-2F9Z Phase 1 [376]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Transcription factor MafB (MAFB)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Tretinoin DM49DUI Acne vulgaris ED80 Approved [208]
Panobinostat DM58WKG Chronic graft versus host disease Approved [68]
Calcitriol DM8ZVJ7 Congenital alopecia LC30 Approved [120]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [82]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Zoledronate DMIXC7G Adenocarcinoma 2D40 Approved [90]
Temozolomide DMKECZD Adenocarcinoma 2D40 Approved [91]
Cupric Sulfate DMP0NFQ Fungal infection 1F29-1F2F Approved [73]
Cisplatin DMRHGI9 Adenocarcinoma 2D40 Approved [233]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [210]
⏷ Show the Full List of 10 Drug(s)
Drug(s) Affected By Sodium/nucleoside cotransporter 1 (SLC28A1)
Drug Name Drug ID Indication ICD 11 Highest Status REF
Uridine DMQTREB Depression 6A70-6A7Z Approved [767]
Ciclosporin DMAZJFX Graft-versus-host disease 4B24 Approved [71]
Valproate DMCFE9I Epilepsy 8A60-8A68 Approved [72]
Rosiglitazone DMILWZR Chronic kidney disease GB61 Approved [79]
Acetaminophen DMUIE76 Allergic rhinitis CA08.0 Approved [178]
Zidovudine DM4KI7O Human immunodeficiency virus infection 1C62 Approved [768]
Adenosine DMM2NSK Paroxysmal supraventricular tachycardia BC81.Z Approved [768]
Decitabine DMQL8XJ Acute myelogenous leukaemia 2A41 Approved [769]
DEOXYCYTIDINE DMYE5LJ Acute myeloid leukaemia 2A60 Approved [767]
Urethane DM7NSI0 N. A. N. A. Phase 4 [215]
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Molecular Interaction Atlas of This Drug

Molecular Interaction Atlas
Download the Complete Interaction Atlas for Visualization in Cytoscape

Drug Therapeutic Target (DTT)
DTT Name DTT ID UniProt ID MOA REF
DNA [cytosine-5]-methyltransferase (DNMT) TTHVCUP NOUNIPROTAC Inhibitor [3]

Drug-Metabolizing Enzyme (DME)
DME Name DME ID UniProt ID MOA REF
Cytidine aminohydrolase (CDA) DEKEDRC CDD_HUMAN Substrate [4]
Cytidine deaminase (cdd) DEYILK4 E0TLJ6_MYCHH Substrate [5]

Drug Off-Target (DOT)
DOT Name DOT ID UniProt ID Interaction REF
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1 (PLCB1) OT9HYT7A PLCB1_HUMAN Gene/Protein Processing [6]
15-hydroxyprostaglandin dehydrogenase (HPGD) OTYZI6JB PGDH_HUMAN Post-Translational Modifications [7]
5'-nucleotidase (NT5E) OT7J5LT6 5NTD_HUMAN Gene/Protein Processing [8]
A disintegrin and metalloproteinase with thrombospondin motifs 1 (ADAMTS1) OTTLJH8W ATS1_HUMAN Gene/Protein Processing [8]
Acyl-CoA 6-desaturase (FADS2) OTUX531P FADS2_HUMAN Gene/Protein Processing [8]
Adenylate kinase isoenzyme 5 (AK5) OTTGXLOT KAD5_HUMAN Gene/Protein Processing [8]
Afadin- and alpha-actinin-binding protein (SSX2IP) OTEIZ7N1 ADIP_HUMAN Gene/Protein Processing [8]
Albumin (ALB) OTVMM513 ALBU_HUMAN Gene/Protein Processing [9]
Alpha-2,8-sialyltransferase 8B (ST8SIA2) OTRBBBD8 SIA8B_HUMAN Gene/Protein Processing [8]
Alpha-fetoprotein (AFP) OT9GG3ZI FETA_HUMAN Gene/Protein Processing [9]

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