General Information of Disease (ID: DIS0BZB5)

Disease Name Hyperglycemia
Disease Class MA18: Blood chemistry clinical sympton
Definition Abnormally high level of glucose in the blood.
Disease Hierarchy
DIS5IK09: Glucose metabolism disease
DIS0BZB5: Hyperglycemia
ICD Code
ICD-11
ICD-11: MA18.0
ICD-10
ICD-10: R73, R73.9
ICD-9
ICD-9: 790.29
Expand ICD-11
'MA18.0
Expand ICD-10
'R73; 'R73.9
Expand ICD-9
790.29
Disease Identifiers
MONDO ID
MONDO_0002909
MESH ID
D006943
UMLS CUI
C0020456
MedGen ID
5689
HPO ID
HP:0003074
SNOMED CT ID
237598005

Drug-Interaction Atlas (DIA) of This Disease

Drug-Interaction Atlas (DIA)
This Disease is Treated as An Indication in 1 Investigative Drug(s)
Drug Name Drug ID Highest Status Drug Type REF
GSC-1 DMTKGA3 Investigative NA [1]
------------------------------------------------------------------------------------

Molecular Interaction Atlas (MIA) of This Disease

Molecular Interaction Atlas (MIA)
This Disease Is Related to 254 DTT Molecule(s)
Gene Name DTT ID Evidence Level Mode of Inheritance REF
ABCC8 TTP835K Limited Genetic Variation [2]
AKR1B1 TTFBNVI Limited Biomarker [3]
APOA4 TTNC3WS Limited Biomarker [4]
APOL1 TTDB8PW Limited Biomarker [5]
ARRB1 TTMVD4A Limited Altered Expression [6]
ARRB2 TT8SO2I Limited Altered Expression [6]
CACNA1D TT7RGTM Limited Altered Expression [7]
CAPN1 TT1WBIJ Limited Altered Expression [8]
CD163 TTTZ9DE Limited Biomarker [9]
CDC25C TTESBNC Limited Altered Expression [10]
CMKLR1 TT4UGZL Limited Biomarker [11]
ECE1 TTQ9RYT Limited Altered Expression [12]
ELAVL1 TTPC9D0 Limited Biomarker [13]
EPHX2 TT7WVHI Limited Altered Expression [14]
ESRRG TT9ZRHB Limited Biomarker [15]
FABP1 TTIV96N Limited Biomarker [16]
FN3K TTP6W8J Limited Biomarker [17]
GALR1 TTX3HNZ Limited Biomarker [18]
GCH1 TTLSWP6 Limited Altered Expression [19]
GP6 TTTJUVZ Limited Biomarker [20]
HKDC1 TTVUI8G Limited Altered Expression [21]
HMGA1 TTBA219 Limited Biomarker [22]
ICAM1 TTA1L39 Limited Biomarker [23]
INS TTZOPHG Limited Biomarker [24]
ITGAM TTB69FJ Limited Biomarker [9]
KAT2B TTVK7SB Limited Biomarker [25]
LIPE TTLUQ8E Limited Biomarker [26]
MAP4K4 TT6NI13 Limited Altered Expression [27]
MFGE8 TT1GLAJ Limited Biomarker [28]
MSI2 TTTXQF6 Limited Genetic Variation [29]
MSTN TTM8I2X Limited Altered Expression [30]
NCK1 TTMA3VF Limited Biomarker [31]
OPRK1 TTQW87Y Limited Biomarker [32]
PLTP TTZF6SN Limited Altered Expression [33]
PPID TTNAFOU Limited Altered Expression [34]
PPIF TTRFQTB Limited Altered Expression [34]
PRDX4 TTPBL9I Limited Therapeutic [35]
PRKAR1A TTNAHEX Limited Biomarker [36]
S1PR2 TTVSMOH Limited Biomarker [37]
SDC2 TT5H2F0 Limited Biomarker [38]
SIRPA TTBRJS9 Limited Biomarker [39]
SLC1A3 TT8WRDA Limited Biomarker [40]
SLC22A8 TTTQR47 Limited Biomarker [41]
SLC38A4 TTJE54U Limited Genetic Variation [42]
SORD TTLSRBZ Limited Biomarker [43]
SORT1 TTRX9AV Limited Altered Expression [44]
SUV39H1 TTUWQTK Limited Altered Expression [45]
TICAM1 TT2GQT6 Limited Altered Expression [46]
TMPRSS2 TT1GM2Z Limited Biomarker [47]
TRPM5 TT1N8F3 Limited Biomarker [48]
BRD9 TTR7L5Y Disputed Biomarker [49]
CTSA TT5NILS Disputed Biomarker [50]
STAR TTEI40H Disputed Biomarker [51]
TBXA2R TT2O84V Disputed Biomarker [52]
TRPA1 TTELV3W Disputed Biomarker [53]
VEGFB TTPJQHE Disputed Biomarker [54]
ACAT1 TTK3C21 Strong Biomarker [55]
ACE2 TTUI5H7 Strong Biomarker [56]
ADA TTLP57V Strong Biomarker [57]
ADCY5 TTN64VU Strong Biomarker [58]
ADIPOQ TTXKA7D Strong Biomarker [59]
ADK TTL732K Strong Biomarker [60]
ADRB1 TTR6W5O Strong Biomarker [61]
AGER TTMO9HF Strong Biomarker [62]
AGTR1 TT8DBY3 Strong Biomarker [63]
AIMP2 TTXWHGF Strong Biomarker [64]
ALDH2 TTFLN4T Strong Biomarker [65]
AMY2A TTCGSZ4 Strong Altered Expression [66]
AOC3 TT7HC21 Strong Altered Expression [67]
APOB TTN1IE2 Strong Genetic Variation [68]
APOC3 TTXOZQ1 Strong Altered Expression [69]
ARG1 TT7ZQEV Strong Biomarker [64]
ATF3 TTCE793 Strong Biomarker [70]
AVP TTJ8EWH Strong Biomarker [71]
BMP7 TTKOBRA Strong Altered Expression [72]
BRD7 TT07ZS1 Strong Biomarker [73]
CBL TT7QT13 Strong Biomarker [74]
CCL2 TTNAY0P Strong Altered Expression [75]
CD36 TTPJMCU Strong Altered Expression [76]
CD40 TT1ERKL Strong Biomarker [9]
CD59 TTBGTEJ Strong Biomarker [77]
CD86 TT53XHB Strong Altered Expression [78]
CDH5 TTXLCFO Strong Biomarker [79]
CNTF TTGEM5Q Strong Biomarker [80]
CRK TTFEUYR Strong Biomarker [64]
CTDSP1 TTHZAF0 Strong Biomarker [81]
CYBB TT5T8MR Strong Biomarker [82]
CYP11A1 TTSYVO6 Strong Biomarker [83]
DDR2 TTU98HG Strong Altered Expression [84]
DPP4 TTDIGC1 Strong Altered Expression [85]
DRD1 TTZFYLI Strong Biomarker [86]
DUSP9 TT1GV6C Strong Altered Expression [87]
EHMT2 TTS6RZT Strong Altered Expression [88]
ENPP1 TTZTIWS Strong Genetic Variation [89]
EPAS1 TTWPA54 Strong Biomarker [90]
FABP4 TTHWMFZ Strong Biomarker [91]
FFAR1 TTB8FUC Strong Biomarker [92]
FGF1 TTMY81X Strong Biomarker [93]
FGF21 TTQ916P Strong Biomarker [94]
FGR TTPOGS1 Strong Altered Expression [95]
FOXO1 TTLRVIA Strong Biomarker [96]
FST TTDNM9W Strong Altered Expression [97]
FTO TTFW3BT Strong Genetic Variation [98]
G6PC TTBQMJ8 Strong Altered Expression [99]
GAL TTXZAJ5 Strong Biomarker [100]
GCGR TT9O6WS Strong Altered Expression [101]
GCK TTDLNGZ Strong Biomarker [102]
GIP TT40HS5 Strong Altered Expression [103]
GIPR TTYMKBE Strong Biomarker [104]
GLO1 TTV9A7R Strong Biomarker [105]
GPBAR1 TTSDVTR Strong Biomarker [106]
GPX1 TTYAHBP Strong Biomarker [107]
GRK2 TTAZ3MN Strong Biomarker [108]
HBB TTM6HK1 Strong Genetic Variation [109]
HCN2 TT9EUT4 Strong Biomarker [110]
HCN4 TTQP04A Strong Biomarker [110]
HCRT TTU5HJP Strong Biomarker [111]
HCRTR2 TT9N02I Strong Therapeutic [112]
HK2 TTK02H8 Strong Biomarker [113]
HMGB1 TTWQYB7 Strong Biomarker [114]
HNF4A TT2F3CD Strong Biomarker [102]
HRH3 TT9JNIC Strong Biomarker [115]
HSD11B1 TTN7BL9 Strong Altered Expression [116]
HSPB8 TTY0OJN Strong Biomarker [117]
HSPD1 TT9HL5R Strong Altered Expression [118]
HTR2A TTJQOD7 Strong Genetic Variation [119]
HTR2C TTWJBZ5 Strong Genetic Variation [119]
IAPP TTHN8EM Strong Biomarker [120]
IL6 TTT1V78 Strong Biomarker [121]
IRS1 TTAJSQ0 Strong Altered Expression [122]
KCNJ11 TT329V4 Strong Genetic Variation [123]
LDHA TTW76JE Strong Altered Expression [124]
LEP TTBJEZ5 Strong Biomarker [125]
LEPR TT0HD6V Strong Biomarker [126]
LONP1 TTM1VPZ Strong Biomarker [127]
LPL TTOF3WZ Strong Altered Expression [128]
MAPK14 TTQBR95 Strong Biomarker [129]
MBL2 TTMQDZ5 Strong Biomarker [130]
MC4R TTD0CIQ Strong Biomarker [125]
MGAM TTXWASR Strong Biomarker [131]
MTNR1B TT32JK8 Strong Biomarker [132]
NCF1 TTZ4JC3 Strong Biomarker [82]
NFE2L2 TTA6ZN2 Strong Biomarker [127]
NOS3 TTCM4B3 Strong Biomarker [133]
NOX4 TTQRBSJ Strong Altered Expression [134]
NQO1 TT8XK6L Strong Altered Expression [135]
NR3C2 TT26PHO Strong Biomarker [136]
NRG4 TTWAGKJ Strong Biomarker [137]
P2RX1 TTJW7B3 Strong Biomarker [138]
P2RX3 TT2THBD Strong Biomarker [138]
P2RX4 TT1NLOA Strong Biomarker [138]
P2RX7 TT473XN Strong Biomarker [138]
P2RY2 TTOZHQC Strong Biomarker [138]
PCSK1 TTED9LZ Strong Biomarker [139]
PDX1 TT8SGZK Strong Biomarker [140]
PKLR TT31N4S Strong Biomarker [141]
PLA2G1B TT9V5JH Strong Biomarker [142]
PLA2G4A TTT1JVS Strong Biomarker [143]
PPARD TT2JWF6 Strong Biomarker [144]
PPP2CA TTHTKNY Strong Altered Expression [110]
PRKCA TTFJ8Q1 Strong Altered Expression [145]
PRKCB TTYPXQF Strong Altered Expression [146]
PRKCZ TTBSN0L Strong Altered Expression [147]
PRNP TTY5F9C Strong Biomarker [148]
PTGS2 TTVKILB Strong Genetic Variation [149]
PTK2B TTTEFBV Strong Biomarker [150]
PTPN1 TTELIN2 Strong Biomarker [151]
REN TTB2MXP Strong Altered Expression [152]
RIPK2 TTCQ2E5 Strong Biomarker [153]
ROBO4 TT3S9TY Strong Biomarker [154]
ROCK1 TTZN7RP Strong Altered Expression [155]
RORC TTGV6LY Strong Biomarker [156]
ROS1 TTSZ6Y3 Strong Biomarker [24]
S1PR3 TTDYP7I Strong Biomarker [157]
SELP TTE5VG0 Strong Biomarker [158]
SETD2 TTPC3H4 Strong Biomarker [159]
SGK1 TTTV8EJ Strong Altered Expression [160]
SIRT3 TTVZLIJ Strong Biomarker [161]
SIRT5 TTH0IOD Strong Biomarker [161]
SLC11A2 TT2IS7P Strong Altered Expression [145]
SLC17A5 TTFSUIA Strong Altered Expression [162]
SLC2A4 TTP6MT5 Strong Biomarker [163]
SLC30A8 TTXIGT7 Strong Genetic Variation [164]
SLC5A1 TT2UE56 Strong Biomarker [165]
SLC5A2 TTF8JAT Strong Biomarker [166]
SP1 TTZEP6S Strong Altered Expression [167]
TCF7L2 TT80QAL Strong Genetic Variation [98]
TGM2 TT2F4OL Strong Biomarker [24]
THBS1 TTKI0H1 Strong Biomarker [96]
TRPC6 TTRBT3W Strong Biomarker [168]
TTR TTPOYU7 Strong Biomarker [169]
TXN TTZJ5U9 Strong Altered Expression [170]
TXNIP TTTLDZK Strong Biomarker [171]
UCP2 TTSC2YM Strong Altered Expression [172]
UCP3 TT12RJK Strong Altered Expression [173]
USP14 TTVSYP9 Strong Biomarker [174]
UTRN TTNO1VA Strong Biomarker [175]
VCAM1 TTHCEF6 Strong Altered Expression [176]
VDAC1 TTAMKGB Strong Altered Expression [177]
VDAC2 TTM1I7L Strong Biomarker [177]
VWF TT3SZBT Strong Altered Expression [178]
WNK1 TTJ9UMX Strong Biomarker [179]
ABCA1 TTJW1GN Definitive Altered Expression [180]
ADORA2B TTNE7KG Definitive Altered Expression [181]
ADRB3 TTMXGCW Definitive Genetic Variation [182]
ALOX15 TTN9T81 Definitive Altered Expression [183]
AQP7 TTNGCRK Definitive Biomarker [184]
AQP9 TTQEI32 Definitive Altered Expression [185]
ATIC TT9NVXQ Definitive Biomarker [186]
CEBPA TT5LWG1 Definitive Altered Expression [187]
CRTC2 TTFWETR Definitive Altered Expression [188]
CRY1 TT5MLZR Definitive Biomarker [189]
CSF1 TT0IQER Definitive Biomarker [190]
DDIT4 TTVEOY6 Definitive Altered Expression [191]
DLK1 TTF4AVB Definitive Altered Expression [192]
F2RL3 TTD0652 Definitive Altered Expression [193]
G6PC2 TT7EV4P Definitive Genetic Variation [194]
GPRC6A TTI1PRE Definitive Genetic Variation [195]
HIPK2 TTOB49C Definitive Biomarker [196]
HMGCR TTPADOQ Definitive Genetic Variation [197]
HSF1 TTN6STZ Definitive Altered Expression [198]
IDE TT2EDHU Definitive Altered Expression [199]
IL1R1 TTWOTEA Definitive Altered Expression [200]
KDM1A TTNR0UQ Definitive Biomarker [201]
LTBR TTFO0PM Definitive Biomarker [202]
LY96 TT8S9AV Definitive Biomarker [203]
METAP2 TTZL0OI Definitive Biomarker [204]
MMP16 TTNP4CU Definitive Biomarker [203]
MRGPRX1 TTIX6PK Definitive Genetic Variation [195]
NAMPT TTD1WIG Definitive Altered Expression [205]
NRN1 TTS05MJ Definitive Biomarker [206]
OXER1 TT7WBSV Definitive Genetic Variation [195]
PRKCD TT7A1BO Definitive Altered Expression [207]
PRKCI TTWJTHX Definitive Biomarker [208]
PRMT1 TTVOJAI Definitive Altered Expression [209]
PTGDR2 TTQDMX5 Definitive Biomarker [210]
REG3A TTL4H8N Definitive Altered Expression [211]
RENBP TTZCG0Q Definitive Biomarker [62]
SCN10A TT90XZ8 Definitive Altered Expression [212]
SCT TTOBVIN Definitive Biomarker [213]
SETD7 TTJ0FSU Definitive Biomarker [214]
SGPL1 TT618Q2 Definitive Biomarker [215]
SIK1 TT1H6LC Definitive Altered Expression [188]
SMN1 TT8QL6X Definitive Altered Expression [216]
SNAP25 TTYQWA0 Definitive Altered Expression [217]
SREBF1 TTER0UB Definitive Altered Expression [218]
SREBF2 TTRQ4AP Definitive Altered Expression [219]
TKT TT04R7I Definitive Altered Expression [220]
TNFRSF14 TTWGTC1 Definitive Biomarker [202]
TRH TT2Z39D Definitive Genetic Variation [221]
TRPC3 TTNVC34 Definitive Biomarker [222]
UGCG TTPHEX3 Definitive Biomarker [223]
ULK1 TT4D7MJ Definitive Biomarker [65]
UNC13B TT948FC Definitive Biomarker [224]
------------------------------------------------------------------------------------
⏷ Show the Full List of 254 DTT(s)
This Disease Is Related to 11 DTP Molecule(s)
Gene Name DTP ID Evidence Level Mode of Inheritance REF
SLC25A19 DTT82QK Limited Biomarker [225]
SLC25A3 DTCRIWV Limited Biomarker [226]
SLC6A6 DTHWCVA Limited Altered Expression [227]
SLC20A1 DTMULXV Strong Altered Expression [228]
SLC24A3 DTO18LP Strong Biomarker [229]
SLC2A2 DTUJPOL Strong Biomarker [230]
SLC30A10 DTYBI73 Definitive Genetic Variation [164]
SLC30A7 DTQK38X Definitive Biomarker [231]
SLC35A1 DTVZIRG Definitive Biomarker [232]
SLC39A7 DTDQSAM Definitive Biomarker [231]
SLC5A3 DT8ACN1 Definitive Altered Expression [233]
------------------------------------------------------------------------------------
⏷ Show the Full List of 11 DTP(s)
This Disease Is Related to 15 DME Molecule(s)
Gene Name DME ID Evidence Level Mode of Inheritance REF
EGLN3 DEMQTKH Limited Altered Expression [234]
FAAH DEUM1EX Limited Biomarker [235]
FMO3 DEP76YL Limited Biomarker [236]
GFPT2 DERQCJM Limited Altered Expression [237]
GLDC DEIN8FB Limited Genetic Variation [238]
PCK1 DEPLH5Z Limited Altered Expression [239]
PON2 DEHJU7E Limited Biomarker [240]
CRMP1 DE0EUXB Strong Biomarker [175]
GGCT DEKW6PB Strong Genetic Variation [241]
GPT DER5HFI Strong Biomarker [242]
NT5C2 DE1DOKJ Strong Biomarker [243]
PNPO DE3Z1RA Strong Biomarker [244]
SI DE5EO4Y Strong Biomarker [131]
SULT1E1 DESTKG6 Strong Biomarker [245]
GLS DE3E0VT Definitive Altered Expression [246]
------------------------------------------------------------------------------------
⏷ Show the Full List of 15 DME(s)
This Disease Is Related to 273 DOT Molecule(s)
Gene Name DOT ID Evidence Level Mode of Inheritance REF
ACSM3 OT0AE1IV Limited Biomarker [247]
AGFG1 OTI8ZKC4 Limited Biomarker [248]
ALX3 OTXZ25PZ Limited Biomarker [249]
AMPD1 OTU17BCI Limited Genetic Variation [250]
ATG4B OTQ4RNRM Limited Biomarker [251]
ATP2A3 OTFYDEES Limited Genetic Variation [252]
BHLHE22 OTZUQY5L Limited Biomarker [253]
CAPN10 OTS9LJW4 Limited Genetic Variation [254]
CCN3 OTOW5YL4 Limited Altered Expression [255]
CCT2 OTW1VV4E Limited Altered Expression [256]
CNBP OTTGM9NK Limited Biomarker [257]
CNDP1 OTOYSQG7 Limited Altered Expression [258]
COL3A1 OTT1EMLM Limited Biomarker [259]
CPT1A OTI862QH Limited Biomarker [260]
CPT2 OTIN6G20 Limited Biomarker [260]
CYBA OT16N9ZO Limited Altered Expression [261]
CYP2W1 OTXSB1AE Limited Genetic Variation [262]
DCAF1 OT3ZDVOE Limited Biomarker [248]
DDAH2 OT8Q40G2 Limited Altered Expression [263]
DEAF1 OTCLX3ZW Limited Altered Expression [264]
DEFB1 OT5SV0E4 Limited Altered Expression [265]
DEGS1 OT4WXPKW Limited Biomarker [266]
DESI1 OTFNIW98 Limited Biomarker [267]
DGKD OTNI8HAH Limited Biomarker [268]
DYNC1H1 OTD1KRKO Limited Genetic Variation [269]
ELOVL5 OT375W1Z Limited Altered Expression [270]
ERRFI1 OT7VZ2IZ Limited Biomarker [271]
FAM3C OTBR6U9G Limited Altered Expression [272]
FBN1 OTYCJT63 Limited Biomarker [259]
FBXO2 OTF3677S Limited Altered Expression [273]
FCGR3B OTSLSPZG Limited Biomarker [9]
FGB OT6RKLI9 Limited Genetic Variation [274]
FLVCR1 OT9XCFOC Limited Altered Expression [275]
FTSJ1 OTNE7W96 Limited Biomarker [276]
FTSJ3 OT3J8P0B Limited Biomarker [276]
GALNT2 OTZZ5386 Limited Biomarker [277]
GFER OTVK43OK Limited Biomarker [11]
HAS2 OTTD3PAL Limited Altered Expression [278]
HCLS1 OTX7WGYN Limited Biomarker [279]
HLA-DMB OT17HGXJ Limited Biomarker [280]
IFI30 OT9DERT1 Limited Genetic Variation [281]
IGF2BP2 OT4ZSEEE Limited Genetic Variation [282]
INPP5F OTPKUY50 Limited Biomarker [283]
KHSRP OTDHZARB Limited Biomarker [279]
KLF10 OT4F4UGS Limited Biomarker [284]
LPCAT3 OTWI96P4 Limited Altered Expression [142]
LRBA OTOUZN9G Limited Biomarker [285]
MAFA OTBCA105 Limited Altered Expression [286]
MARCHF3 OT89V4N5 Limited Altered Expression [287]
NEXN OTKB0B0H Limited Biomarker [288]
NFIL3 OTQH9HM3 Limited Altered Expression [289]
NGDN OTBXTCN5 Limited Altered Expression [290]
NOX5 OTHTH59G Limited Posttranslational Modification [291]
OBP2A OTBIJ5TI Limited Altered Expression [292]
OR10A4 OTYYB8SY Limited Genetic Variation [293]
PES1 OTMZK7XE Limited Biomarker [287]
PICK1 OT8QE6EU Limited Biomarker [294]
PIN4 OT403QC1 Limited Altered Expression [99]
PLXNA1 OTN0BING Limited Altered Expression [255]
PPP1R11 OTSHYPPW Limited Biomarker [295]
PROX1 OT68R6IO Limited Altered Expression [296]
PTBP2 OTF4S7NE Limited Altered Expression [264]
PTPN4 OT6SXU5Y Limited Biomarker [297]
PTPN9 OTNAR1I2 Limited Biomarker [226]
PTPRN OTAP7NOL Limited Biomarker [298]
PTPRU OTHDO0QG Limited Biomarker [226]
PTRH1 OTOAOS93 Limited Genetic Variation [299]
RAB10 OT8ZN26V Limited Biomarker [300]
RAB8A OTPB54Y3 Limited Biomarker [300]
RETSAT OTC3AOPX Limited Biomarker [301]
RHEB OTFLTSEC Limited Biomarker [302]
RHOT1 OTBIRR8Q Limited Biomarker [303]
RPAIN OTBMXAYK Limited Biomarker [248]
RPL10 OTBHOZGC Limited Altered Expression [255]
RPL29 OTUFIBJL Limited Biomarker [304]
RPL36A OT1LYV85 Limited Biomarker [271]
SERP1 OT60XXUP Limited Biomarker [305]
SH2B1 OTJZO2CI Limited Biomarker [306]
SIGLEC7 OTNDLURR Limited Biomarker [279]
SIX2 OTYOVGSC Limited Altered Expression [307]
SIX3 OTP5E3VU Limited Altered Expression [307]
SLC35G1 OTKZUA8O Limited Biomarker [267]
SNED1 OTBQVXY5 Limited Altered Expression [308]
SRSF10 OTY6IJ11 Limited Altered Expression [264]
ST13 OTNML6UP Limited Biomarker [304]
STK24 OTGUHOIL Limited Biomarker [309]
TAS2R13 OTSTOX5G Limited Altered Expression [310]
TFE3 OTM99ZWH Limited Biomarker [311]
THRAP3 OTG25JOG Limited Altered Expression [312]
TRIM69 OTTEGTRD Limited Altered Expression [46]
TSC22D4 OTNMQGZS Limited Biomarker [292]
ADIPOR2 OT2HDTL8 Disputed Altered Expression [313]
AQP5 OT77GBY8 Disputed Biomarker [314]
DACT1 OT19Z704 Disputed Altered Expression [315]
FGL1 OTT0QHQ1 Disputed Biomarker [316]
GPX5 OTQMMNNT Disputed Biomarker [317]
KIFBP OT1XADKG Disputed Biomarker [318]
MCF2L2 OTOGFMIH Disputed Biomarker [53]
MICU1 OTS7N0LE Disputed Altered Expression [319]
NFE2 OTLM94BI Disputed Altered Expression [320]
NPVF OTIMUS0X Disputed Biomarker [321]
NRTN OT4PAKUY Disputed Biomarker [322]
FANCC OTTIDM3P moderate Biomarker [323]
PPARGC1A OTHCDQ22 moderate Altered Expression [324]
A1CF OTJBKFA1 Strong Biomarker [325]
ADIPOR1 OT65ZFZN Strong Biomarker [326]
AGGF1 OTA7U2T8 Strong Biomarker [327]
AHSA1 OTC7AFHT Strong Biomarker [64]
ANGPTL8 OTQFINCD Strong Biomarker [328]
APPL1 OT8VR95S Strong Biomarker [329]
ARF6 OTVV7KJO Strong Altered Expression [330]
ASAH1 OT1DNGXL Strong Biomarker [331]
ASPG OT5E2EKR Strong Biomarker [332]
ATN1 OTNZFLKY Strong Biomarker [333]
BGLAP OTK1YLWQ Strong Altered Expression [334]
BNIP3 OT4SO7J4 Strong Biomarker [335]
C1QL1 OTNQ0G3E Strong Biomarker [336]
CENPX OTG1RAKJ Strong Biomarker [337]
CHMP2B OTZA7RJB Strong Altered Expression [145]
CORO7 OTG7MEAJ Strong Altered Expression [338]
COX4I1 OTU0FC24 Strong Altered Expression [339]
COX4I2 OTB98B21 Strong Altered Expression [339]
CREM OTJIJ5AL Strong Altered Expression [340]
CRISP2 OT8HLTV5 Strong Altered Expression [341]
CTDSP2 OTT2BOJG Strong Biomarker [81]
CYC1 OT0962IM Strong Genetic Variation [342]
DAPK2 OTWODUQG Strong Biomarker [175]
DBP OTE0W7LN Strong Biomarker [343]
DECR1 OTCDIR6X Strong Biomarker [344]
DENR OTXP9HOY Strong Biomarker [175]
DMRT1 OT5PU9U1 Strong Altered Expression [145]
DNM1L OTXK1Q1G Strong Biomarker [175]
DUOX1 OTQ2AEW0 Strong Biomarker [345]
DUOX2 OTU14HCN Strong Biomarker [345]
DUSP26 OTI7WIYN Strong Biomarker [346]
EEF1A2 OT9Z23K5 Strong Altered Expression [347]
EMCN OTS03CZC Strong Altered Expression [348]
ENHO OT91QASK Strong Biomarker [349]
ENO2 OTRODL0T Strong Altered Expression [350]
FAM3B OTC2S91N Strong Altered Expression [351]
FBRS OTUVH446 Strong Genetic Variation [352]
FBXO8 OTZNGJGW Strong Genetic Variation [352]
FOXK2 OTFXDZ3R Strong Biomarker [353]
FOXO3 OTHXQG4P Strong Altered Expression [354]
GABPA OT9YB2SA Strong Biomarker [127]
GATA6 OTO2BC0F Strong Altered Expression [216]
GCKR OTSIWXGG Strong Genetic Variation [355]
GOLGA6A OTHU9MRX Strong Biomarker [356]
GORASP1 OTQS91S7 Strong Biomarker [179]
GPR142 OT6UFQCL Strong Biomarker [177]
GRAP2 OTS5NIZ3 Strong Biomarker [64]
GYS1 OTJZJRWK Strong Altered Expression [204]
HSPA12A OTFOCDD6 Strong Biomarker [357]
INS-IGF2 OTZR74BO Strong Genetic Variation [358]
INTU OTXB13E6 Strong Biomarker [359]
KLF11 OTKVQDJD Strong Altered Expression [360]
KLF15 OTGMQMVR Strong Biomarker [361]
KLF2 OTIP1UFX Strong Biomarker [133]
KLF9 OTBFEJRQ Strong Biomarker [362]
LECT2 OTSFZ9JD Strong Biomarker [363]
MAP2K6 OTK13JKC Strong Biomarker [364]
MFAP1 OTZN4FT3 Strong Genetic Variation [365]
MLXIPL OTR9MLLW Strong Altered Expression [366]
MOK OTQK7M9V Strong Biomarker [62]
MPG OTAHW80B Strong Genetic Variation [241]
MRAP2 OTCQS7DB Strong Genetic Variation [367]
NCOA1 OTLIUJQD Strong Altered Expression [95]
NCOA2 OTMQFPBB Strong Altered Expression [95]
NEUROD1 OTZQ7QJ2 Strong Biomarker [368]
NFAT5 OTKIE59S Strong Altered Expression [369]
NLRC4 OTAIA3NA Strong Posttranslational Modification [370]
NT5C3A OT67KZJA Strong Biomarker [371]
NUCB2 OTHO6JWN Strong Biomarker [372]
P2RX2 OT0LF34A Strong Biomarker [138]
P2RX6 OT1FNTXA Strong Biomarker [138]
PC OT6O0V51 Strong Biomarker [344]
PDHX OTG7O271 Strong Biomarker [140]
PDK4 OTCMHMBZ Strong Genetic Variation [373]
PFKM OT1QY9JM Strong Altered Expression [218]
PID1 OT5YJ7FI Strong Biomarker [374]
PIK3R1 OT5BZ1J9 Strong Biomarker [375]
PLAGL1 OTZAO900 Strong Altered Expression [376]
PLIN2 OTRXJ9UN Strong Altered Expression [377]
POLDIP2 OT8SZSJ6 Strong Biomarker [64]
POU1F1 OTXT8A5C Strong Altered Expression [228]
PRKAA1 OT7TNF0L Strong Biomarker [378]
PRKAA2 OTU1KZPV Strong Biomarker [379]
PRKAB1 OT1OG4QZ Strong Biomarker [378]
PROK2 OT70IFEZ Strong Genetic Variation [380]
PRRT2 OTCJUBDO Strong Altered Expression [146]
QRFP OTX5FZDJ Strong Biomarker [381]
QRFPR OT31N14I Strong Biomarker [381]
RAPGEF5 OT53VS75 Strong Biomarker [382]
RASGRP1 OTX9WN2E Strong Biomarker [383]
RCBTB1 OTAYELI8 Strong Biomarker [356]
RNF10 OTF7Y6M7 Strong Altered Expression [384]
RNF19A OTKWCV80 Strong Biomarker [64]
RPTOR OT4TQZ9F Strong Genetic Variation [385]
SCP2 OTPAFCPQ Strong Biomarker [81]
SCPEP1 OT43LYEZ Strong Biomarker [81]
SCUBE1 OT4JY1UY Strong Altered Expression [386]
SDC4 OTKUVUGZ Strong Biomarker [387]
SEMA3C OTEGUY7F Strong Biomarker [388]
SHBG OTPWU5IW Strong Biomarker [389]
SNAP47 OT1DE2QT Strong Biomarker [67]
SPZ1 OTQH8HJ5 Strong Altered Expression [341]
SRXN1 OTYDBO4L Strong Biomarker [390]
ST3GAL4 OTNENJZQ Strong Biomarker [391]
STAP2 OTEB1VVI Strong Biomarker [392]
SYCP1 OTWFV4KA Strong Biomarker [81]
SYCP2 OTBH622S Strong Biomarker [81]
SYT1 OTVTPOI6 Strong Biomarker [179]
TBC1D1 OTI9V7B0 Strong Biomarker [393]
TCF21 OT393IMA Strong Altered Expression [338]
TIMM8A OTDX9687 Strong Biomarker [394]
TLX2 OTPFAUM8 Strong Biomarker [229]
TRIB3 OTG5OS7X Strong Altered Expression [395]
ALDOB OT7FR69A Definitive Altered Expression [396]
BTC OTW4B2O0 Definitive Biomarker [397]
CADM2 OT45PVKC Definitive Biomarker [398]
CAV3 OTWSFDB4 Definitive Altered Expression [399]
CERS2 OTRAHYYP Definitive Biomarker [400]
COMP OTS2FPMI Definitive Altered Expression [401]
DAB2 OTRMQTMZ Definitive Altered Expression [402]
DLG1 OTCRZYWT Definitive Altered Expression [403]
DOC2B OTRUMZ8C Definitive Biomarker [404]
EFHD2 OTM9VMN3 Definitive Biomarker [405]
ELOVL1 OTIDTQ8R Definitive Biomarker [400]
FAM3A OTK1X62Z Definitive Biomarker [406]
FGFBP3 OTWM1KCM Definitive Altered Expression [407]
FOXP2 OTVX6A59 Definitive Biomarker [408]
GAL3ST1 OTSFFZRD Definitive Biomarker [232]
GALP OTW25XLK Definitive Altered Expression [409]
GFPT1 OTQBDO45 Definitive Genetic Variation [410]
GLIS3 OTBC960E Definitive Biomarker [411]
GPR151 OT7EACU6 Definitive Genetic Variation [195]
GYS2 OTCKIUYR Definitive Genetic Variation [412]
HBG2 OT4J48JJ Definitive Biomarker [413]
HHIP OT77RQYS Definitive Altered Expression [414]
HMCN1 OTLZAS0P Definitive Biomarker [415]
HOXD13 OTWSC8TF Definitive Biomarker [416]
IARS1 OT9WXH5N Definitive Altered Expression [417]
KCNH6 OTQ52G7V Definitive Genetic Variation [418]
LUC7L3 OTKDED8A Definitive Biomarker [419]
MAP2 OT6UYT3X Definitive Biomarker [204]
MCAT OTH07FIW Definitive Altered Expression [204]
MRGPRX3 OTRKCCDS Definitive Genetic Variation [195]
MRGPRX4 OTOBHZVA Definitive Genetic Variation [195]
MTA2 OTCCYIQJ Definitive Biomarker [420]
MTMR11 OTHL2O08 Definitive Biomarker [419]
NEDD4L OT1B19RU Definitive Altered Expression [403]
NEU1 OTH9BY8Y Definitive Biomarker [50]
NEUROG3 OT6DIPWC Definitive Biomarker [421]
NRK OTGR01FF Definitive Biomarker [422]
NSA2 OTRU5QPO Definitive Biomarker [287]
PCK2 OTJ8LX4N Definitive Altered Expression [99]
PHLPP1 OTIFXW8D Definitive Altered Expression [135]
PLB1 OTZ6TTYV Definitive Biomarker [142]
POLD4 OTG578YH Definitive Biomarker [204]
POLE4 OTCMWUT6 Definitive Biomarker [204]
PRDX6 OTS8KC8A Definitive Altered Expression [423]
PRSS55 OTXXWI5Y Definitive Altered Expression [341]
RBP3 OTIWM4GT Definitive Altered Expression [424]
RCAN1 OT1MVXC7 Definitive Altered Expression [425]
RFC1 OT3L5PK3 Definitive Altered Expression [220]
RPS19 OTBKGP48 Definitive Biomarker [426]
SELENOP OT02B8IR Definitive Biomarker [363]
SLC16A4 OT1YXBKC Definitive Altered Expression [204]
SMIM1 OTWSFC2F Definitive Biomarker [427]
SMN2 OT54RLO1 Definitive Altered Expression [216]
SNAP23 OTY2MYBX Definitive Biomarker [428]
STAM OT6X5RR1 Definitive Biomarker [429]
TFAM OTXXV5V7 Definitive Altered Expression [324]
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⏷ Show the Full List of 273 DOT(s)

References

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23 Potential roles of chromium on inflammatory biomarkers in diabetes: A Systematic.Clin Exp Pharmacol Physiol. 2019 Nov;46(11):975-983. doi: 10.1111/1440-1681.13144. Epub 2019 Aug 16.
24 Proinsulin C-peptide prevents hyperglycemia-induced vascular leakage and metastasis of melanoma cells in the lungs of diabetic mice.FASEB J. 2019 Jan;33(1):750-762. doi: 10.1096/fj.201800723R. Epub 2018 Jul 18.
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28 Correction of MFG-E8 Resolves Inflammation and Promotes Cutaneous Wound Healing in Diabetes.J Immunol. 2016 Jun 15;196(12):5089-100. doi: 10.4049/jimmunol.1502270. Epub 2016 May 18.
29 Differential DNA methylation of MSI2 and its correlation with diabetic traits.PLoS One. 2017 May 24;12(5):e0177406. doi: 10.1371/journal.pone.0177406. eCollection 2017.
30 Adeno-associated virus-mediated expression of myostatin propeptide improves the growth of skeletal muscle and attenuates hyperglycemia in db/db mice.Gene Ther. 2017 Mar;24(3):167-175. doi: 10.1038/gt.2016.85. Epub 2016 Dec 16.
31 A remote cis-acting variant at 3q links glomerular NCK1 to diabetic nephropathy.PLoS One. 2013;8(2):e56414. doi: 10.1371/journal.pone.0056414. Epub 2013 Feb 18.
32 G protein coupled receptor kinase-2 upregulation causes -opioid receptor desensitization in diabetic heart.Biochem Biophys Res Commun. 2017 Jan 22;482(4):658-664. doi: 10.1016/j.bbrc.2016.11.090. Epub 2016 Nov 16.
33 Glucose regulates the transcription of human genes relevant to HDL metabolism: responsive elements for peroxisome proliferator-activated receptor are involved in the regulation of phospholipid transfer protein.Diabetes. 2001 Aug;50(8):1851-6. doi: 10.2337/diabetes.50.8.1851.
34 Synergistic exacerbation of mitochondrial and synaptic dysfunction and resultant learning and memory deficit in a mouse model of diabetic Alzheimer's disease.J Alzheimers Dis. 2015;43(2):451-63. doi: 10.3233/JAD-140972.
35 Overexpression of peroxiredoxin 4 protects against high-dose streptozotocin-induced diabetes by suppressing oxidative stress and cytokines in transgenic mice.Antioxid Redox Signal. 2010 Nov 15;13(10):1477-90. doi: 10.1089/ars.2010.3137.
36 PKA signaling drives reticularis differentiation and sexually dimorphic adrenal cortex renewal.JCI Insight. 2018 Jan 25;3(2):e98394. doi: 10.1172/jci.insight.98394. eCollection 2018 Jan 25.
37 Role of sphingosine-1-phosphate receptor 1 and sphingosine-1-phosphate receptor 2 in hyperglycemia-induced endothelial cell dysfunction.Int J Mol Med. 2015 Apr;35(4):1103-8. doi: 10.3892/ijmm.2015.2100. Epub 2015 Feb 12.
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39 Down-regulation of Insulin Receptor Substrate 1 during Hyperglycemia Induces Vascular Smooth Muscle Cell Dedifferentiation.J Biol Chem. 2017 Feb 3;292(5):2009-2020. doi: 10.1074/jbc.M116.758987. Epub 2016 Dec 21.
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53 STZ causes depletion of immune cells in sciatic nerve and dorsal root ganglion in experimental diabetes.J Neuroimmunol. 2017 May 15;306:76-82. doi: 10.1016/j.jneuroim.2017.03.008. Epub 2017 Mar 11.
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58 Novel mechanism of increasing cerebral vascular constriction in acute hyperglycemia and diabetes through adenylyl cyclase 5-generated cyclic adenosine monophosphate.J Diabetes Investig. 2020 Jul;11(4):783-785. doi: 10.1111/jdi.13186. Epub 2019 Dec 23.
59 Pharmacological Activities of Alisma orientale against Nonalcoholic Fatty Liver Disease and Metabolic Syndrome: Literature Review.Evid Based Complement Alternat Med. 2019 Jun 3;2019:2943162. doi: 10.1155/2019/2943162. eCollection 2019.
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62 Type 2 Diabetes Mellitus Increases The Risk of Late-Onset Alzheimer's Disease: Ultrastructural Remodeling of the Neurovascular Unit and Diabetic Gliopathy.Brain Sci. 2019 Sep 29;9(10):262. doi: 10.3390/brainsci9100262.
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65 ULK1-regulated autophagy: A mechanism in cellular protection for ALDH2 against hyperglycemia.Toxicol Lett. 2018 Feb;283:106-115. doi: 10.1016/j.toxlet.2017.11.008. Epub 2017 Nov 8.
66 Lactucaxanthin - a potential anti-diabetic carotenoid from lettuce (Lactuca sativa) inhibits -amylase and -glucosidase activity in vitro and in diabetic rats.Food Funct. 2017 Mar 22;8(3):1124-1131. doi: 10.1039/c6fo01655c.
67 Serum vascular adhesion protein-1 is up-regulated in hyperglycemia and is associated with incident diabetes negatively.Int J Obes (Lond). 2019 Mar;43(3):512-522. doi: 10.1038/s41366-018-0172-4. Epub 2018 Jul 18.
68 Linagliptin improves endothelial function in patients with type 2 diabetes: A randomized study of linagliptin effectiveness on endothelial function.J Diabetes Investig. 2017 May;8(3):330-340. doi: 10.1111/jdi.12587. Epub 2016 Nov 21.
69 Increased apolipoprotein C3 drives cardiovascular risk in type 1 diabetes.J Clin Invest. 2019 Jul 11;129(10):4165-4179. doi: 10.1172/JCI127308.
70 ATF3 expression in cardiomyocytes preserves homeostasis in the heart and controls peripheral glucose tolerance.Cardiovasc Res. 2017 Feb;113(2):134-146. doi: 10.1093/cvr/cvw228. Epub 2016 Nov 7.
71 SGLT2 inhibition increases serum copeptin in young adults with type 1 diabetes.Diabetes Metab. 2020 Jun;46(3):203-209. doi: 10.1016/j.diabet.2019.11.006. Epub 2019 Dec 6.
72 BMP7 improves insulin signal transduction in the liver via inhibition of mitogen-activated protein kinases.J Endocrinol. 2019 Nov;243(2):97-110. doi: 10.1530/JOE-18-0693.
73 BRD7 deficiency leads to the development of obesity and hyperglycemia.Sci Rep. 2019 Mar 29;9(1):5327. doi: 10.1038/s41598-019-41713-0.
74 Evidence for a role of the ubiquitin-proteasome pathway in pancreatic islets.Diabetes. 2006 May;55(5):1223-31. doi: 10.2337/db05-0450.
75 Effect of stress hyperglycaemia on monocyte chemoattractant protein-1 levels and the short-term prognosis of patients with acute ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention.Exp Ther Med. 2019 May;17(5):3823-3829. doi: 10.3892/etm.2019.7338. Epub 2019 Mar 4.
76 CD36 overexpression: a possible etiopathogenic mechanism of atherosclerosis in patients with prediabetes and diabetes.Diabetol Metab Syndr. 2017 Jul 18;9:55. doi: 10.1186/s13098-017-0253-x. eCollection 2017.
77 A distinctive histidine residue is essential for in vivo glycation-inactivation of human CD59 transgenically expressed in mice erythrocytes: Implications for human diabetes complications.Am J Hematol. 2017 Nov;92(11):1198-1203. doi: 10.1002/ajh.24886. Epub 2017 Sep 8.
78 Brief exposure to hyperglycemia activates dendritic cells in vitro and in vivo.J Cell Physiol. 2020 Jun;235(6):5120-5129. doi: 10.1002/jcp.29380. Epub 2019 Nov 1.
79 NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy.Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4538-4547. doi: 10.1073/pnas.1814711116. Epub 2019 Feb 20.
80 Reduced ciliary neuronotrophic factor-like activity in nerves from diabetic or galactose-fed rats.Brain Res. 1992 Mar 20;575(2):320-4. doi: 10.1016/0006-8993(92)90097-s.
81 Physicochemical properties of polysaccharides separated from Camellia oleifera Abel seed cake and its hypoglycemic activity on streptozotocin-induced diabetic mice.Int J Biol Macromol. 2019 Mar 15;125:1075-1083. doi: 10.1016/j.ijbiomac.2018.12.059. Epub 2018 Dec 5.
82 Inhibition of Hypothalamic Inhibitor B Kinase /Nuclear Transcription Factor B Pathway Attenuates Metabolism and Cardiac Dysfunction in Type 2 Diabetic Rats.Neuroendocrinology. 2020;110(11-12):899-913. doi: 10.1159/000504444. Epub 2019 Oct 31.
83 Effects of high levels of glucose on the steroidogenesis and the expression of adiponectin receptors in rat ovarian cells.Reprod Biol Endocrinol. 2008 Mar 19;6:11. doi: 10.1186/1477-7827-6-11.
84 Discoidin domain Receptor 2: A determinant of metabolic syndrome-associated arterial fibrosis in non-human primates.PLoS One. 2019 Dec 5;14(12):e0225911. doi: 10.1371/journal.pone.0225911. eCollection 2019.
85 Physiology and Pharmacology of DPP-4 in Glucose Homeostasis and the Treatment of Type 2 Diabetes.Front Endocrinol (Lausanne). 2019 Feb 15;10:80. doi: 10.3389/fendo.2019.00080. eCollection 2019.
86 Glycaemic control with insulin prevents the reduced renal dopamine D1 receptor expression and function in streptozotocin-induced diabetes.Nephrol Dial Transplant. 2010 Sep;25(9):2945-53. doi: 10.1093/ndt/gfq150. Epub 2010 Mar 25.
87 Expression of Dual-Specificity Phosphatase 9 in Placenta and Its Relationship with Gestational Diabetes Mellitus.J Diabetes Res. 2019 Oct 20;2019:1963178. doi: 10.1155/2019/1963178. eCollection 2019.
88 High blood sugar levels but not diabetes mellitus significantly enhance oxaliplatin chemoresistance in patients with stage III colorectal cancer receiving adjuvant FOLFOX6 chemotherapy.Ther Adv Med Oncol. 2019 Aug 20;11:1758835919866964. doi: 10.1177/1758835919866964. eCollection 2019.
89 Adipose Tissue Insulin Resistance in Gestational Diabetes.Metab Syndr Relat Disord. 2017 Mar;15(2):86-92. doi: 10.1089/met.2016.0124. Epub 2017 Jan 12.
90 Adaptation to hypoxia in the diabetic rat kidney.Kidney Int. 2008 Jan;73(1):34-42. doi: 10.1038/sj.ki.5002567. Epub 2007 Oct 3.
91 The short-chain fatty acid propionate increases glucagon and FABP4 production, impairing insulin action in mice and humans.Sci Transl Med. 2019 Apr 24;11(489):eaav0120. doi: 10.1126/scitranslmed.aav0120.
92 Fasiglifam (TAK-875), a G Protein-Coupled Receptor 40 (GPR40) Agonist, May Induce Hepatotoxicity through Reactive Oxygen Species Generation in a GPR40-Dependent Manner.Biomol Ther (Seoul). 2018 Nov 1;26(6):599-607. doi: 10.4062/biomolther.2017.225.
93 The Hypothalamic Arcuate Nucleus-Median Eminence Is a Target for Sustained Diabetes Remission Induced by Fibroblast Growth Factor 1.Diabetes. 2019 May;68(5):1054-1061. doi: 10.2337/db19-0025. Epub 2019 Feb 22.
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346 Adipsin preserves beta cells in diabetic mice and associates with protection from type 2 diabetes in humans.Nat Med. 2019 Nov;25(11):1739-1747. doi: 10.1038/s41591-019-0610-4. Epub 2019 Nov 7.
347 eEF1A2 exacerbated insulin resistance in male skeletal muscle via PKC and ER stress.J Endocrinol. 2020 Jan 1;244(1):25-40. doi: 10.1530/JOE-19-0051.
348 Endomucin restores depleted endothelial glycocalyx in the retinas of streptozotocin-induced diabetic rats.FASEB J. 2019 Dec;33(12):13346-13357. doi: 10.1096/fj.201901161R. Epub 2019 Sep 21.
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364 Inhibition of cyclin-dependent kinase 5 activity alleviates diabetes-related cognitive deficits.FASEB J. 2019 Dec;33(12):14506-14515. doi: 10.1096/fj.201901292R. Epub 2019 Nov 5.
365 Blackcurrant Extract Ameliorates Hyperglycemia in Type 2 Diabetic Mice in Association with Increased Basal Secretion of Glucagon-Like Peptide-1 and Activation of AMP-Activated Protein Kinase.J Nutr Sci Vitaminol (Tokyo). 2018;64(4):258-264. doi: 10.3177/jnsv.64.258.
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367 Loss-of-function mutations in MRAP2 are pathogenic in hyperphagic obesity with hyperglycemia and hypertension.Nat Med. 2019 Nov;25(11):1733-1738. doi: 10.1038/s41591-019-0622-0. Epub 2019 Nov 7.
368 Genetic Dissection and Clinical Features of MODY6 (NEUROD1-MODY).Curr Diab Rep. 2019 Feb 22;19(3):12. doi: 10.1007/s11892-019-1130-9.
369 Transcriptional Regulator TonEBP Mediates Oxidative Damages in Ischemic Kidney Injury.Cells. 2019 Oct 20;8(10):1284. doi: 10.3390/cells8101284.
370 Hyperglycemia-induced inflamm-aging accelerates gingival senescence via NLRC4 phosphorylation.J Biol Chem. 2019 Dec 6;294(49):18807-18819. doi: 10.1074/jbc.RA119.010648. Epub 2019 Nov 1.
371 Effects on the Caco-2 Cells of a Hypoglycemic Protein from Lupin Seeds in a Solution and Adsorbed on Polystyrene Nanoparticles to Mimic a Complex Food Matrix.Biomolecules. 2019 Oct 14;9(10):606. doi: 10.3390/biom9100606.
372 Carbohydrate oxidation and glucose utilisation under hyperglycaemia in aged and young males during exercise at the same relative exercise intensity.Eur J Appl Physiol. 2019 Jan;119(1):235-245. doi: 10.1007/s00421-018-4019-4. Epub 2018 Oct 23.
373 Aberrant PDK4 Promoter Methylation Preceding Hyperglycemia in a Mouse Model.Appl Biochem Biotechnol. 2020 Mar;190(3):1023-1034. doi: 10.1007/s12010-019-03143-6. Epub 2019 Oct 26.
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376 Transient neonatal diabetes mellitus gene Zac1 impairs insulin secretion in mice through Rasgrf1.Mol Cell Biol. 2012 Jul;32(13):2549-60. doi: 10.1128/MCB.06637-11. Epub 2012 Apr 30.
377 Type 2 diabetes is associated with suppression of autophagy and lipid accumulation in -cells.J Cell Mol Med. 2019 Apr;23(4):2890-2900. doi: 10.1111/jcmm.14172. Epub 2019 Feb 1.
378 Pharmacological AMPK activation induces transcriptional responses congruent to exercise in skeletal and cardiac muscle, adipose tissues and liver.PLoS One. 2019 Feb 27;14(2):e0211568. doi: 10.1371/journal.pone.0211568. eCollection 2019.
379 Protective effects of sulforaphane on type 2 diabetes-induced cardiomyopathy via AMPK-mediated activation of lipid metabolic pathways and NRF2 function.Metabolism. 2020 Jan;102:154002. doi: 10.1016/j.metabol.2019.154002. Epub 2019 Nov 9.
380 New roles for prokineticin 2 in feeding behavior, insulin resistance and type 2 diabetes: Studies in mice and humans.Mol Metab. 2019 Nov;29:182-196. doi: 10.1016/j.molmet.2019.08.016. Epub 2019 Aug 28.
381 Neuropeptide 26RFa (QRFP) is a key regulator of glucose homeostasis and its activity is markedly altered in obese/hyperglycemic mice.Am J Physiol Endocrinol Metab. 2019 Jul 1;317(1):E147-E157. doi: 10.1152/ajpendo.00540.2018. Epub 2019 May 14.
382 Macula Densa SGLT1-NOS1-Tubuloglomerular Feedback Pathway, a New Mechanism for Glomerular Hyperfiltration during Hyperglycemia.J Am Soc Nephrol. 2019 Apr;30(4):578-593. doi: 10.1681/ASN.2018080844. Epub 2019 Mar 13.
383 RasGRP1 is a target for VEGF to induce angiogenesis and involved in the endothelial-protective effects of metformin under high glucose in HUVECs.IUBMB Life. 2019 Sep;71(9):1391-1400. doi: 10.1002/iub.2072. Epub 2019 May 23.
384 RING finger protein10 is a potential drug target for diabetic vascular complications.Mol Med Rep. 2019 Aug;20(2):931-938. doi: 10.3892/mmr.2019.10358. Epub 2019 Jun 6.
385 Polymorphisms associated with everolimus pharmacokinetics, toxicity and survival in metastatic breast cancer. PLoS One. 2017 Jul 20;12(7):e0180192.
386 Evaluation of SCUBE-1 levels as a placental dysfunction marker at gestational diabetes mellitus.Gynecol Endocrinol. 2020 May;36(5):417-420. doi: 10.1080/09513590.2019.1683537. Epub 2019 Oct 31.
387 Matrix metalloproteinase-9 mediated shedding of syndecan-4 in glomerular endothelial cells.Microcirculation. 2019 Jan 31:e12534. doi: 10.1111/micc.12534. Online ahead of print.
388 Opposing Effects of Neuropilin-1 and -2 on Sensory Nerve Regeneration in Wounded Corneas: Role of Sema3C in Ameliorating Diabetic Neurotrophic Keratopathy.Diabetes. 2019 Apr;68(4):807-818. doi: 10.2337/db18-1172. Epub 2019 Jan 24.
389 Insulin resistance and sex hormone-binding globulin are independently correlated with low free testosterone levels in obese males.Andrologia. 2018 Sep;50(7):e13035. doi: 10.1111/and.13035. Epub 2018 May 9.
390 Sulfiredoxin-1 alleviates high glucose-induced podocyte injury though promoting Nrf2/ARE signaling via inactivation of GSK-3.Biochem Biophys Res Commun. 2019 Sep 3;516(4):1137-1144. doi: 10.1016/j.bbrc.2019.06.157. Epub 2019 Jul 6.
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392 Highly Selective Protein Tyrosine Phosphatase Inhibitor, 2,2',3,3'-Tetrabromo-4,4',5,5'-tetrahydroxydiphenylmethane, Ameliorates Type 2 Diabetes Mellitus in BKS db Mice.Mol Pharm. 2019 May 6;16(5):1839-1850. doi: 10.1021/acs.molpharmaceut.8b01106. Epub 2019 Apr 18.
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394 Tyrosine kinase inhibitor imatinib modulates the viability and apoptosis of castrate-resistant prostate cancer cells dependently on the glycolytic environment.Life Sci. 2019 Feb 1;218:274-283. doi: 10.1016/j.lfs.2018.12.055. Epub 2018 Dec 31.
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396 The Expression of Aldolase B in Islets Is Negatively Associated With Insulin Secretion in Humans.J Clin Endocrinol Metab. 2018 Dec 1;103(12):4373-4383. doi: 10.1210/jc.2018-00791.
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398 Cadm2 regulates body weight and energy homeostasis in mice.Mol Metab. 2018 Feb;8:180-188. doi: 10.1016/j.molmet.2017.11.010. Epub 2017 Nov 22.
399 Hyperglycemia-Induced Oxidative Stress Abrogates Remifentanil Preconditioning-Mediated Cardioprotection in Diabetic Rats by Impairing Caveolin-3-Modulated PI3K/Akt and JAK2/STAT3 Signaling.Oxid Med Cell Longev. 2019 Sep 5;2019:9836302. doi: 10.1155/2019/9836302. eCollection 2019.
400 Disrupted sphingolipid metabolism following acute clozapine and olanzapine administration.J Biomed Sci. 2018 May 2;25(1):40. doi: 10.1186/s12929-018-0437-1.
401 Cartilage Oligomeric Matrix Protein Levels in Type 2 Diabetes Associated with Primary Knee Osteoarthritis Patients.Genet Test Mol Biomarkers. 2019 Jan;23(1):16-22. doi: 10.1089/gtmb.2018.0184. Epub 2018 Dec 8.
402 MicroRNA-145 regulates disabled-2 and Wnt3a expression in cardiomyocytes under hyperglycaemia.Eur J Clin Invest. 2018 Jan;48(1). doi: 10.1111/eci.12867. Epub 2017 Dec 8.
403 O-GlcNAcylation of cardiac Nav1.5 contributes to the development of arrhythmias in diabetic hearts.Int J Cardiol. 2018 Jun 1;260:74-81. doi: 10.1016/j.ijcard.2018.02.099. Epub 2018 Feb 27.
404 Doc2b Protects -Cells Against Inflammatory Damage and Enhances Function.Diabetes. 2018 Jul;67(7):1332-1344. doi: 10.2337/db17-1352. Epub 2018 Apr 16.
405 Swiprosin-1 Promotes Mitochondria-Dependent Apoptosis of Glomerular Podocytes via P38 MAPK Pathway in Early-Stage Diabetic Nephropathy.Cell Physiol Biochem. 2018;45(3):899-916. doi: 10.1159/000487285. Epub 2018 Feb 2.
406 FAM3 gene family: A promising therapeutical target for NAFLD and type 2 diabetes.Metabolism. 2018 Apr;81:71-82. doi: 10.1016/j.metabol.2017.12.001. Epub 2017 Dec 6.
407 Fibroblast Growth Factor Binding Protein 3 (FGFBP3) impacts carbohydrate and lipid metabolism.Sci Rep. 2018 Oct 29;8(1):15973. doi: 10.1038/s41598-018-34238-5.
408 MiR-34a Regulates Axonal Growth of Dorsal Root Ganglia Neurons by Targeting FOXP2 and VAT1 in Postnatal and Adult Mouse.Mol Neurobiol. 2018 Dec;55(12):9089-9099. doi: 10.1007/s12035-018-1047-3. Epub 2018 Apr 10.
409 High Circulating Alarin Levels Are Associated with Presence of Metabolic Syndrome.Cell Physiol Biochem. 2018;51(5):2041-2051. doi: 10.1159/000495823. Epub 2018 Dec 6.
410 A Genetic Model to Study Increased Hexosamine Biosynthetic Flux.Endocrinology. 2017 Aug 1;158(8):2420-2426. doi: 10.1210/en.2017-00359.
411 GLIS3 binds pancreatic beta cell regulatory regions alongside other islet transcription factors.J Endocrinol. 2019 Jul 1:JOE-19-0182.R2. doi: 10.1530/JOE-19-0182. Online ahead of print.
412 Mutational analysis of the GYS2 gene in patients diagnosed with ketotic hypoglycaemia.J Pediatr Endocrinol Metab. 2012;25(9-10):963-7. doi: 10.1515/jpem-2012-0165.
413 Physical and Chemical Processes and the Morphofunctional Characteristics of Human Erythrocytes in Hyperglycaemia.Front Physiol. 2017 Aug 30;8:606. doi: 10.3389/fphys.2017.00606. eCollection 2017.
414 Hedgehog Interacting Protein Promotes Fibrosis and Apoptosis in Glomerular Endothelial Cells in Murine Diabetes.Sci Rep. 2018 Apr 13;8(1):5958. doi: 10.1038/s41598-018-24220-6.
415 Hemicentin 1 influences podocyte dynamic changes in glomerular diseases.Am J Physiol Renal Physiol. 2018 Jun 1;314(6):F1154-F1165. doi: 10.1152/ajprenal.00198.2017. Epub 2018 Feb 28.
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417 A Lanosteryl triterpene from Protorhus longifolia augments insulin signaling in type 1 diabetic rats.BMC Complement Altern Med. 2018 Oct 1;18(1):265. doi: 10.1186/s12906-018-2337-z.
418 From Hyper- to Hypoinsulinemia and Diabetes: Effect of KCNH6 on Insulin Secretion.Cell Rep. 2018 Dec 26;25(13):3800-3810.e6. doi: 10.1016/j.celrep.2018.12.005.
419 Increase in insulin sensitivity by the association of chicoric acid and chlorogenic acid contained in a natural chicoric acid extract (NCRAE) of chicory (Cichorium intybus L.) for an antidiabetic effect.J Ethnopharmacol. 2018 Apr 6;215:241-248. doi: 10.1016/j.jep.2017.12.035. Epub 2018 Jan 9.
420 Model Free iPID Control for Glycemia Regulation of Type-1 Diabetes.IEEE Trans Biomed Eng. 2018 Jan;65(1):199-206. doi: 10.1109/TBME.2017.2698036. Epub 2017 Apr 25.
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424 Retinol binding protein 3 is increased in the retina of patients with diabetes resistant to diabetic retinopathy.Sci Transl Med. 2019 Jul 3;11(499):eaau6627. doi: 10.1126/scitranslmed.aau6627.
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