Details of the Drug Combination

General Information of Drug Combination (ID: DCG6UGG)

Drug Combination Name
Fulvestrant PF-05212384
Indication
Disease Entry Status REF
Breast Cancer Phase 3 [1]
Component Drugs Fulvestrant   DM0YZC6 PF-05212384   DMBL3VD
Small molecular drug Small molecular drug
2D MOL 2D MOL
3D MOL 3D MOL

Molecular Interaction Atlas of This Drug Combination

Molecular Interaction Atlas (MIA)
Indication(s) of Fulvestrant
Disease Entry ICD 11 Status REF
Breast cancer 2C60-2C65 Approved [2]
Fulvestrant Interacts with 1 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Estrogen receptor (ESR) TTZAYWL ESR1_HUMAN Antagonist [12]
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Fulvestrant Interacts with 2 DME Molecule(s)
DME Name DME ID UniProt ID Mode of Action REF
Cytochrome P450 3A4 (CYP3A4) DE4LYSA CP3A4_HUMAN Metabolism [13]
UDP-glucuronosyltransferase 1A1 (UGT1A1) DEYGVN4 UD11_HUMAN Metabolism [14]
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Fulvestrant Interacts with 985 DOT Molecule(s)
DOT Name DOT ID UniProt ID Mode of Action REF
Superoxide dismutase (SOD1) OT39TA1L SODC_HUMAN Increases Expression [5]
Transferrin receptor protein 1 (TFRC) OT8ZPBDL TFR1_HUMAN Increases Expression [5]
Transcription factor Jun (JUN) OTCYBO6X JUN_HUMAN Increases Expression [5]
Integrin beta-1 (ITGB1) OT6G1IAR ITB1_HUMAN Increases Expression [5]
Macrophage colony-stimulating factor 1 (CSF1) OT68M7RD CSF1_HUMAN Increases Expression [5]
DNA topoisomerase 2-alpha (TOP2A) OT6LPS08 TOP2A_HUMAN Increases Expression [5]
C-C motif chemokine 5 (CCL5) OTSCA5CK CCL5_HUMAN Increases Expression [5]
G2/mitotic-specific cyclin-B1 (CCNB1) OT19S7E5 CCNB1_HUMAN Increases Expression [5]
Ephrin type-A receptor 1 (EPHA1) OTGJMRZ0 EPHA1_HUMAN Increases Expression [5]
Proteinase-activated receptor 1 (F2R) OT4WVWBO PAR1_HUMAN Increases Expression [5]
Cyclin-dependent kinase inhibitor 1 (CDKN1A) OTQWHCZE CDN1A_HUMAN Increases Expression [5]
Caspase-4 (CASP4) OTVQTV1L CASP4_HUMAN Increases Expression [5]
Dual specificity protein kinase CLK1 (CLK1) OTG1LACW CLK1_HUMAN Increases Expression [5]
Ras-related protein Rab-2A (RAB2A) OT6SK83U RAB2A_HUMAN Increases Expression [5]
CCHC-type zinc finger nucleic acid binding protein (CNBP) OTTGM9NK CNBP_HUMAN Increases Expression [5]
Dynein light chain 1, cytoplasmic (DYNLL1) OTR69LHT DYL1_HUMAN Increases Expression [5]
Paired box protein Pax-5 (PAX5) OTYBJJWX PAX5_HUMAN Increases Expression [5]
GA-binding protein alpha chain (GABPA) OT9YB2SA GABPA_HUMAN Increases Expression [5]
Mitogen-activated protein kinase kinase kinase 11 (MAP3K11) OT0EYZAY M3K11_HUMAN Increases Expression [5]
ATP-binding cassette sub-family C member 3 (ABCC3) OTC3IJV4 MRP3_HUMAN Increases Expression [4]
ATP-binding cassette sub-family C member 5 (ABCC5) OT34G4US MRP5_HUMAN Decreases Expression [4]
Transforming acidic coiled-coil-containing protein 1 (TACC1) OTGX20TE TACC1_HUMAN Increases Expression [4]
Cystatin-A (CSTA) OT1K68KE CYTA_HUMAN Decreases Expression [4]
Protein c-Fos (FOS) OTJBUVWS FOS_HUMAN Decreases Expression [4]
Myc proto-oncogene protein (MYC) OTPV5LUK MYC_HUMAN Decreases Expression [4]
Receptor tyrosine-protein kinase erbB-2 (ERBB2) OTOAUNCK ERBB2_HUMAN Increases Expression [4]
Proliferating cell nuclear antigen (PCNA) OTHZ1RIA PCNA_HUMAN Decreases Expression [4]
Cyclin-A2 (CCNA2) OTPHHYZJ CCNA2_HUMAN Decreases Expression [4]
Ephrin-A1 (EFNA1) OTU2NUA2 EFNA1_HUMAN Increases Expression [4]
Insulin-like growth factor-binding protein 4 (IGFBP4) OT2HZRBD IBP4_HUMAN Decreases Expression [4]
Insulin receptor substrate 1 (IRS1) OTNO82CU IRS1_HUMAN Decreases Expression [4]
CCN family member 3 (CCN3) OTOW5YL4 CCN3_HUMAN Increases Expression [4]
Matrix metalloproteinase-15 (MMP15) OT1XF517 MMP15_HUMAN Increases Expression [4]
Neprilysin (MME) OT5Q39P8 NEP_HUMAN Increases Expression [15]
Interferon alpha-inducible protein 6 (IFI6) OTWOOAM4 IFI6_HUMAN Increases Expression [15]
Amphiregulin (AREG) OTJFOR67 AREG_HUMAN Decreases Expression [15]
Trefoil factor 3 (TFF3) OTJJDRTU TFF3_HUMAN Decreases Expression [15]
Interferon-related developmental regulator 1 (IFRD1) OT4SQMLQ IFRD1_HUMAN Decreases Expression [6]
26S proteasome non-ATPase regulatory subunit 14 (PSMD14) OTJWHMZ5 PSDE_HUMAN Decreases Expression [6]
Aurora kinase A (AURKA) OTMX0HYT AURKA_HUMAN Decreases Expression [6]
Protein phosphatase 1D (PPM1D) OT8NLZ9D PPM1D_HUMAN Decreases Expression [6]
ATP-dependent RNA helicase DDX3Y (DDX3Y) OTKL1FNX DDX3Y_HUMAN Decreases Expression [6]
Asparagine--tRNA ligase, cytoplasmic (NARS1) OTFS4J1W SYNC_HUMAN Decreases Expression [6]
Trafficking kinesin-binding protein 2 (TRAK2) OTXVA7FN TRAK2_HUMAN Decreases Expression [6]
Calsyntenin-1 (CLSTN1) OTQN35G2 CSTN1_HUMAN Decreases Expression [6]
Kinesin-like protein KIF20A (KIF20A) OTXOQHE0 KI20A_HUMAN Decreases Expression [6]
Apolipoprotein D (APOD) OTT77XW8 APOD_HUMAN Increases Expression [6]
Eukaryotic translation initiation factor 2 subunit 1 (EIF2S1) OTM0GDTP IF2A_HUMAN Decreases Expression [6]
Nucleophosmin (NPM1) OTTBYYT0 NPM_HUMAN Decreases Expression [6]
Heat shock protein HSP 90-beta (HSP90AB1) OTR69EG7 HS90B_HUMAN Decreases Expression [6]
Asparagine synthetase (ASNS) OT8R922G ASNS_HUMAN Decreases Expression [6]
Matrix Gla protein (MGP) OTZWU3FU MGP_HUMAN Decreases Expression [6]
High mobility group protein B1 (HMGB1) OT4B7CPF HMGB1_HUMAN Decreases Expression [6]
Pro-cathepsin H (CTSH) OTLFL0DG CATH_HUMAN Increases Expression [6]
60 kDa heat shock protein, mitochondrial (HSPD1) OTTO1Y11 CH60_HUMAN Decreases Expression [6]
Heat shock cognate 71 kDa protein (HSPA8) OTJI2RCI HSP7C_HUMAN Decreases Expression [6]
DNA topoisomerase 1 (TOP1) OT51O0CF TOP1_HUMAN Decreases Expression [6]
Endoplasmin (HSP90B1) OT02XLBR ENPL_HUMAN Decreases Expression [6]
Stathmin (STMN1) OTDJ4RV0 STMN1_HUMAN Decreases Expression [6]
Protein SON (SON) OT9VWV18 SON_HUMAN Decreases Expression [6]
Nucleolin (NCL) OTBXPKMP NUCL_HUMAN Decreases Expression [6]
Heterogeneous nuclear ribonucleoproteins A2/B1 (HNRNPA2B1) OTBZKX4P ROA2_HUMAN Decreases Expression [6]
Nuclear receptor subfamily 4immunitygroup A member 1 (NR4A1) OTGP6GA4 NR4A1_HUMAN Increases Expression [6]
Splicing factor, proline- and glutamine-rich (SFPQ) OTLCIAPJ SFPQ_HUMAN Decreases Expression [6]
Ribonucleoside-diphosphate reductase large subunit (RRM1) OTXGQOR9 RIR1_HUMAN Decreases Expression [6]
Signal transducer CD24 (CD24) OT7CODJ4 CD24_HUMAN Increases Expression [6]
Threonine--tRNA ligase 1, cytoplasmic (TARS1) OT0PWST5 SYTC_HUMAN Decreases Expression [6]
DNA-directed RNA polymerase II subunit RPB2 (POLR2B) OTS3F0H2 RPB2_HUMAN Decreases Expression [6]
Heterogeneous nuclear ribonucleoprotein H (HNRNPH1) OTFRWOLM HNRH1_HUMAN Decreases Expression [6]
Heat shock 70 kDa protein 4 (HSPA4) OT5HR0AR HSP74_HUMAN Decreases Expression [6]
Thrombospondin-2 (THBS2) OTXET551 TSP2_HUMAN Decreases Expression [6]
Coatomer subunit beta' (COPB2) OT82JIGC COPB2_HUMAN Decreases Expression [6]
Lamina-associated polypeptide 2, isoform alpha (TMPO) OTL68EL4 LAP2A_HUMAN Decreases Expression [6]
Signal transducer and activator of transcription 1-alpha/beta (STAT1) OTLMBUZ6 STAT1_HUMAN Decreases Expression [6]
Matrin-3 (MATR3) OTESJ5S7 MATR3_HUMAN Decreases Expression [6]
Ras GTPase-activating-like protein IQGAP1 (IQGAP1) OTZRWTGA IQGA1_HUMAN Decreases Expression [6]
Histone H3-like centromeric protein A (CENPA) OT0NEJ4X CENPA_HUMAN Decreases Expression [6]
Sulfate transporter (SLC26A2) OTJNHNTO S26A2_HUMAN Decreases Expression [6]
Importin subunit alpha-1 (KPNA2) OTU7FOE6 IMA1_HUMAN Decreases Expression [6]
Eukaryotic translation initiation factor 5 (EIF5) OT79PQUN IF5_HUMAN Decreases Expression [6]
Ras-related protein Rap-1A (RAP1A) OT5RH6TI RAP1A_HUMAN Decreases Expression [6]
DNA-dependent protein kinase catalytic subunit (PRKDC) OTJVS4EG PRKDC_HUMAN Decreases Expression [6]
Chromobox protein homolog 1 (CBX1) OT2L4XZX CBX1_HUMAN Decreases Expression [6]
Heterogeneous nuclear ribonucleoprotein U (HNRNPU) OTLQN1E2 HNRPU_HUMAN Decreases Expression [6]
Large ribosomal subunit protein eL6 (RPL6) OTRU71O4 RL6_HUMAN Decreases Expression [6]
DNA topoisomerase 2-beta (TOP2B) OTDHKQZ8 TOP2B_HUMAN Decreases Expression [6]
Serine/arginine-rich splicing factor 1 (SRSF1) OTF61HOV SRSF1_HUMAN Decreases Expression [6]
ATP-dependent RNA helicase A (DHX9) OT5AAOQI DHX9_HUMAN Decreases Expression [6]
Neuroblast differentiation-associated protein AHNAK (AHNAK) OT6KH1WG AHNK_HUMAN Decreases Expression [6]
Zinc transporter ZIP6 (SLC39A6) OTCYF466 S39A6_HUMAN Decreases Expression [6]
Importin subunit beta-1 (KPNB1) OTBT2HFL IMB1_HUMAN Decreases Expression [6]
Proteasome activator complex subunit 4 (PSME4) OTDGF53O PSME4_HUMAN Decreases Expression [6]
Condensin complex subunit 2 (NCAPH) OTXOS97C CND2_HUMAN Decreases Expression [6]
PCNA-associated factor (PCLAF) OTMVIOUU PAF15_HUMAN Decreases Expression [6]
26S proteasome non-ATPase regulatory subunit 6 (PSMD6) OTX59EGK PSMD6_HUMAN Decreases Expression [6]
Elongin-B (ELOB) OTZ3X84T ELOB_HUMAN Decreases Expression [6]
Histone-binding protein RBBP7 (RBBP7) OTLB56HX RBBP7_HUMAN Decreases Expression [6]
Transcription initiation factor TFIID subunit 9 (TAF9) OTCTH3C6 TAF9_HUMAN Decreases Expression [6]
Golgin subfamily A member 5 (GOLGA5) OTG6HB6U GOGA5_HUMAN Decreases Expression [6]
Transportin-1 (TNPO1) OT7W2CM8 TNPO1_HUMAN Decreases Expression [6]
Dehydrodolichyl diphosphate synthase complex subunit NUS1 (NUS1) OT4DQ82L NGBR_HUMAN Decreases Expression [6]
UAP56-interacting factor (FYTTD1) OTXXKQJR UIF_HUMAN Decreases Expression [6]
Rac GTPase-activating protein 1 (RACGAP1) OTQE8IEH RGAP1_HUMAN Decreases Expression [6]
Protein ILRUN (ILRUN) OTE8FHQD ILRUN_HUMAN Decreases Expression [6]
Aryl hydrocarbon receptor nuclear translocator 2 (ARNT2) OTAQD3YV ARNT2_HUMAN Increases Expression [6]
Nucleolar RNA helicase 2 (DDX21) OTV73GMZ DDX21_HUMAN Decreases Expression [6]
Very long chain fatty acid elongase 5 (ELOVL5) OT375W1Z ELOV5_HUMAN Decreases Expression [6]
Serine/threonine-protein kinase 26 (STK26) OTW4QE0D STK26_HUMAN Decreases Expression [6]
Cytochrome P450 1A1 (CYP1A1) OTE4EFH8 CP1A1_HUMAN Increases Expression [16]
Serine/threonine-protein kinase Sgk1 (SGK1) OT301T1U SGK1_HUMAN Decreases Expression [7]
Prostaglandin E synthase (PTGES) OTB7YQFU PTGES_HUMAN Decreases Expression [7]
E3 ubiquitin-protein ligase SIAH2 (SIAH2) OTKED2XN SIAH2_HUMAN Decreases Expression [7]
Carbonic anhydrase 12 (CA12) OT6WNFU8 CAH12_HUMAN Decreases Expression [7]
Tyrosine-protein kinase JAK2 (JAK2) OTBIDOOR JAK2_HUMAN Decreases Expression [7]
monooxygenase MICAL2 (MICAL2) OT04OQQJ MICA2_HUMAN Decreases Expression [7]
Transcription factor AP-2-alpha (TFAP2A) OTMYT3NK AP2A_HUMAN Increases Expression [7]
Proto-oncogene tyrosine-protein kinase receptor Ret (RET) OTLU040A RET_HUMAN Decreases Expression [7]
Monoacylglycerol lipase ABHD2 (ABHD2) OTCRUOCS ABHD2_HUMAN Decreases Expression [7]
Transcriptional activator Myb (MYB) OTJH64IV MYB_HUMAN Decreases Expression [7]
Myb-related protein A (MYBL1) OTBJMC2P MYBA_HUMAN Decreases Expression [7]
Tissue factor pathway inhibitor (TFPI) OTA0FX16 TFPI1_HUMAN Increases Expression [7]
Delta-aminolevulinic acid dehydratase (ALAD) OTHM9GSH HEM2_HUMAN Increases Expression [7]
CD44 antigen (CD44) OT9TTJ41 CD44_HUMAN Decreases Expression [7]
Stromal cell-derived factor 1 (CXCL12) OT2QX5LL SDF1_HUMAN Decreases Expression [7]
Ephrin type-A receptor 4 (EPHA4) OT3AMK0C EPHA4_HUMAN Increases Expression [7]
Single-stranded DNA-binding protein 2 (SSBP2) OTYG1G80 SSBP2_HUMAN Increases Expression [7]
Large neutral amino acids transporter small subunit 1 (SLC7A5) OT2WPVXD LAT1_HUMAN Decreases Expression [7]
DNA-binding protein inhibitor ID-3 (ID3) OTUULW5Z ID3_HUMAN Increases Expression [7]
Urokinase plasminogen activator surface receptor (PLAUR) OTIRKKEQ UPAR_HUMAN Decreases Expression [7]
Early growth response protein 3 (EGR3) OTGPJIRA EGR3_HUMAN Decreases Expression [7]
Forkhead box protein C1 (FOXC1) OTOWZGYO FOXC1_HUMAN Decreases Expression [7]
Cyclin-G2 (CCNG2) OTII38K2 CCNG2_HUMAN Increases Expression [7]
Kynureninase (KYNU) OTINL2RE KYNU_HUMAN Increases Expression [7]
Na(+)/H(+) exchange regulatory cofactor NHE-RF3 (PDZK1) OTGFK4MH NHRF3_HUMAN Decreases Expression [7]
Phosphatidylinositol 3-kinase regulatory subunit gamma (PIK3R3) OTXGJ8N1 P55G_HUMAN Increases Expression [7]
Dual specificity tyrosine-phosphorylation-regulated kinase 2 (DYRK2) OTMDVWPS DYRK2_HUMAN Increases Expression [7]
Transcription factor AP-2 gamma (TFAP2C) OTUDIW05 AP2C_HUMAN Decreases Expression [7]
Serine/threonine-protein kinase Sgk3 (SGK3) OTQ6QO99 SGK3_HUMAN Decreases Expression [7]
Inactive rhomboid protein 1 (RHBDF1) OTCQ7UDS RHDF1_HUMAN Increases Expression [7]
Calmin (CLMN) OT7U5J3T CLMN_HUMAN Increases Expression [7]
DNA endonuclease RBBP8 (RBBP8) OTRHJ3GI CTIP_HUMAN Decreases Expression [7]
Noelin (OLFM1) OTOYPEWW NOE1_HUMAN Decreases Expression [7]
Pleckstrin homology domain-containing family F member 2 (PLEKHF2) OTBGDG8C PKHF2_HUMAN Increases Expression [7]
Spermine oxidase (SMOX) OT11E62Y SMOX_HUMAN Decreases Expression [7]
Nicotinamide riboside kinase 1 (NMRK1) OT0STQLV NRK1_HUMAN Decreases Expression [7]
Rap guanine nucleotide exchange factor-like 1 (RAPGEFL1) OTYKE9ZM RPGFL_HUMAN Decreases Expression [7]
RNA 3'-terminal phosphate cyclase-like protein (RCL1) OT7O00YX RCL1_HUMAN Decreases Expression [7]
Cytochrome P450 1B1 (CYP1B1) OTYXFLSD CP1B1_HUMAN Increases Expression [17]
Extended synaptotagmin-3 (ESYT3) OTG5H3YF ESYT3_HUMAN Increases Methylation [8]
FERM domain-containing protein 3 (FRMD3) OT0CD2GG FRMD3_HUMAN Increases Methylation [8]
Dystrotelin (DYTN) OTC5QZ6R DYTN_HUMAN Increases Methylation [8]
Coiled-coil domain-containing protein 144A (CCDC144A) OTN9UZHR C144A_HUMAN Decreases Methylation [8]
Transmembrane protein 89 (TMEM89) OTZLX09R TMM89_HUMAN Increases Methylation [8]
Delphilin (GRID2IP) OTNDNC0W GRD2I_HUMAN Increases Methylation [8]
Paralemmin-3 (PALM3) OTB83R61 PALM3_HUMAN Increases Methylation [8]
Rho GTPase-activating protein 42 (ARHGAP42) OTIDSJMK RHG42_HUMAN Increases Methylation [8]
Ciliary microtubule inner protein 2C (CIMIP2C) OTKXQKQ4 CMI2C_HUMAN Increases Methylation [8]
Fidgetin-like protein 2 (FIGNL2) OT0GD7S6 FIGL2_HUMAN Increases Methylation [8]
Dorsal root ganglia homeobox protein (DRGX) OTDLEGNE DRGX_HUMAN Increases Methylation [8]
Uncharacterized protein C12orf71 (C12ORF71) OTUFA24U CL071_HUMAN Increases Methylation [8]
Uncharacterized protein C16orf90 (C16ORF90) OTAYN87M CP090_HUMAN Increases Methylation [8]
Isthmin-1 (ISM1) OTZTK2TV ISM1_HUMAN Increases Methylation [8]
Rab GTPase-activating protein 1-like, isoform 10 (RABGAP1L) OT7QO47I RBG10_HUMAN Increases Methylation [8]
Uncharacterized protein C19orf84 (C19ORF84) OT4MVCU6 CS084_HUMAN Increases Methylation [8]
Golgi-associated olfactory signaling regulator (GFY) OTM64CSN GFY_HUMAN Increases Methylation [8]
ATP-dependent RNA helicase DDX39A (DDX39A) OT0Z6E1K DX39A_HUMAN Increases Methylation [8]
Cytosolic acyl coenzyme A thioester hydrolase (ACOT7) OT7C68YV BACH_HUMAN Increases Methylation [8]
Synaptosomal-associated protein 23 (SNAP23) OTY2MYBX SNP23_HUMAN Increases Methylation [8]
Splicing regulator ARVCF (ARVCF) OT78DKOU ARVC_HUMAN Increases Methylation [8]
AP-3 complex subunit beta-1 (AP3B1) OTYTIH5Q AP3B1_HUMAN Decreases Expression [10]
E3 ubiquitin-protein ligase RNF103 (RNF103) OT9DOB4H RN103_HUMAN Increases Methylation [8]
Tumor necrosis factor receptor superfamily member 11B (TNFRSF11B) OTQ4W7MT TR11B_HUMAN Increases Expression [10]
Importin-5 (IPO5) OTAK40ED IPO5_HUMAN Increases Methylation [8]
Histone deacetylase complex subunit SAP18 (SAP18) OTJAZWOL SAP18_HUMAN Increases Methylation [8]
Nuclear receptor subfamily 5 group A member 2 (NR5A2) OTXAUJAS NR5A2_HUMAN Increases Expression [10]
Serine/threonine-protein kinase 25 (STK25) OT4YPNTF STK25_HUMAN Increases Methylation [8]
Receptor-binding cancer antigen expressed on SiSo cells (EBAG9) OTTQLQCP RCAS1_HUMAN Decreases Expression [10]
Pro-neuregulin-2, membrane-bound isoform (NRG2) OTMDE844 NRG2_HUMAN Increases Methylation [8]
Homeobox protein cut-like 2 (CUX2) OTDJTQAJ CUX2_HUMAN Increases Methylation [8]
Suppressor of cytokine signaling 3 (SOCS3) OTY183WJ SOCS3_HUMAN Decreases Expression [10]
Olfactory receptor 7A17 (OR7A17) OTFYB5NE OR7AH_HUMAN Increases Methylation [8]
Telomerase reverse transcriptase (TERT) OT085VVA TERT_HUMAN Decreases Expression [18]
Guanine nucleotide-binding protein subunit beta-5 (GNB5) OT3ZSAXH GNB5_HUMAN Increases Methylation [8]
Kinetochore protein NDC80 homolog (NDC80) OTS7D306 NDC80_HUMAN Decreases Expression [9]
Neuropilin-1 (NRP1) OTCGULYV NRP1_HUMAN Decreases Expression [10]
Ras-specific guanine nucleotide-releasing factor 2 (RASGRF2) OT67DAGF RGRF2_HUMAN Decreases Methylation [8]
Protocadherin-17 (PCDH17) OTRK0M05 PCD17_HUMAN Decreases Methylation [8]
Regulator of G-protein signaling 12 (RGS12) OTNCIQTH RGS12_HUMAN Increases Methylation [8]
Microtubule-associated serine/threonine-protein kinase 4 (MAST4) OT3LOE2J MAST4_HUMAN Increases Methylation [8]
Guanine nucleotide exchange factor DBS (MCF2L) OTEURA8N MCF2L_HUMAN Affects Methylation [8]
Ephrin type-B receptor 6 (EPHB6) OTKNN6GC EPHB6_HUMAN Increases Methylation [8]
Laminin subunit alpha-5 (LAMA5) OTIIXE4M LAMA5_HUMAN Increases Methylation [8]
Ataxin-7 (ATXN7) OTL3YF1H ATX7_HUMAN Decreases Methylation [8]
Tumor protein p73 (TP73) OT0LUO47 P73_HUMAN Increases Methylation [8]
Baculoviral IAP repeat-containing protein 5 (BIRC5) OTILXZYL BIRC5_HUMAN Decreases Expression [9]
Trinucleotide repeat-containing gene 18 protein (TNRC18) OTREUWWG TNC18_HUMAN Decreases Methylation [8]
Tapasin (TAPBP) OTL81AVZ TPSN_HUMAN Increases Methylation [8]
Rho guanine nucleotide exchange factor 9 (ARHGEF9) OTB1FLIW ARHG9_HUMAN Increases Methylation [8]
ERI1 exoribonuclease 3 (ERI3) OT0HIU61 ERI3_HUMAN Increases Methylation [8]
Histone-lysine N-methyltransferase SUV39H1 (SUV39H1) OTDTF5BU SUV91_HUMAN Increases Methylation [8]
Forkhead box protein O3 (FOXO3) OTHXQG4P FOXO3_HUMAN Affects Localization [19]
Protein sprouty homolog 2 (SPRY2) OTH0CRCZ SPY2_HUMAN Affects Methylation [8]
Pleiotropic regulator 1 (PLRG1) OTIVZ5LL PLRG1_HUMAN Increases Methylation [8]
Protein regulator of cytokinesis 1 (PRC1) OTHD0XS0 PRC1_HUMAN Decreases Expression [10]
Mitotic checkpoint serine/threonine-protein kinase BUB1 (BUB1) OT80DZMT BUB1_HUMAN Decreases Expression [9]
Sialic acid-binding Ig-like lectin 6 (SIGLEC6) OTO4F5C9 SIGL6_HUMAN Increases Methylation [8]
Tolloid-like protein 1 (TLL1) OTK9NM7G TLL1_HUMAN Decreases Methylation [8]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like (BNIP3L) OTJKOMXE BNI3L_HUMAN Increases Methylation [8]
NUAK family SNF1-like kinase 1 (NUAK1) OTLLHJJQ NUAK1_HUMAN Increases Methylation [8]
Phospholipid-transporting ATPase VA (ATP10A) OTYF5A7X AT10A_HUMAN Decreases Methylation [8]
Protein ENTREP2 (ENTREP2) OTEUHFKS EREP2_HUMAN Increases Methylation [8]
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma (PIP5K1C) OT3LPG1R PI51C_HUMAN Decreases Methylation [8]
Gasdermin-E (GSDME) OT1ZWY32 GSDME_HUMAN Increases Methylation [8]
Docking protein 2 (DOK2) OTIJ38UF DOK2_HUMAN Increases Methylation [8]
Mitotic checkpoint serine/threonine-protein kinase BUB1 beta (BUB1B) OT8KME51 BUB1B_HUMAN Decreases Expression [9]
Musculin (MSC) OTBRPZL5 MUSC_HUMAN Increases Methylation [8]
Catenin delta-1 (CTNND1) OTUMPSHR CTND1_HUMAN Decreases Methylation [8]
Low-density lipoprotein receptor-related protein 3 (LRP3) OTXMLT8C LRP3_HUMAN Increases Methylation [8]
Protein CBFA2T3 (CBFA2T3) OTOJ10S1 MTG16_HUMAN Increases Methylation [8]
Multiple epidermal growth factor-like domains protein 6 (MEGF6) OTEUYTP1 MEGF6_HUMAN Increases Methylation [8]
Rho-associated protein kinase 2 (ROCK2) OTVYN14T ROCK2_HUMAN Increases Methylation [8]
TSC22 domain family protein 2 (TSC22D2) OTFXF349 T22D2_HUMAN Increases Methylation [8]
Cadherin-16 (CDH16) OTR0GE9G CAD16_HUMAN Increases Methylation [8]
Nuclear receptor corepressor 1 (NCOR1) OT04XNOU NCOR1_HUMAN Increases Expression [10]
Alpha-tectorin (TECTA) OT5E0NE2 TECTA_HUMAN Decreases Methylation [8]
Nuclear receptor subfamily 1 group I member 2 (NR1I2) OTC5U0N5 NR1I2_HUMAN Increases Activity [20]
PC4 and SFRS1-interacting protein (PSIP1) OT4YAFUS PSIP1_HUMAN Increases Methylation [8]
Carbonic anhydrase-related protein 11 (CA11) OT8RX3AJ CAH11_HUMAN Decreases Methylation [8]
Disabled homolog 1 (DAB1) OTPL9MA3 DAB1_HUMAN Increases Methylation [8]
Serpin B7 (SERPINB7) OTZ95LR2 SPB7_HUMAN Increases Methylation [8]
Cell cycle checkpoint protein RAD17 (RAD17) OT1I93DT RAD17_HUMAN Increases Methylation [8]
CCN family member 5 (CCN5) OTADU8JJ CCN5_HUMAN Increases Expression [10]
Regulator of G-protein signaling 20 (RGS20) OT6CGYHW RGS20_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase 17B (STK17B) OT4NYNO8 ST17B_HUMAN Increases Methylation [8]
Slit homolog 2 protein (SLIT2) OTLS2RJ4 SLIT2_HUMAN Increases Methylation [8]
Dendrin (DDN) OTM52ZF5 DEND_HUMAN Increases Methylation [8]
Protein FAM13A (FAM13A) OTZ6GN0Q FA13A_HUMAN Decreases Methylation [8]
G2/mitotic-specific cyclin-B2 (CCNB2) OTIEXTDK CCNB2_HUMAN Decreases Expression [9]
Serine protease 23 (PRSS23) OT6DQAM1 PRS23_HUMAN Increases Methylation [8]
NADH dehydrogenase 1 beta subcomplex subunit 2, mitochondrial (NDUFB2) OT4717TF NDUB2_HUMAN Increases Methylation [8]
Potassium voltage-gated channel subfamily H member 1 (KCNH1) OTZZXWER KCNH1_HUMAN Decreases Expression [21]
NADH dehydrogenase 1 alpha subcomplex subunit 10, mitochondrial (NDUFA10) OTBURQ3A NDUAA_HUMAN Decreases Methylation [8]
CUGBP Elav-like family member 2 (CELF2) OTLJJ4VT CELF2_HUMAN Increases Methylation [8]
Homeobox protein SIX3 (SIX3) OTP5E3VU SIX3_HUMAN Decreases Methylation [8]
Transforming acidic coiled-coil-containing protein 2 (TACC2) OTW4M7HI TACC2_HUMAN Increases Methylation [8]
Supervillin (SVIL) OTWQQ1WK SVIL_HUMAN Increases Methylation [8]
Sodium-dependent phosphate transport protein 2B (SLC34A2) OTLFMBB0 NPT2B_HUMAN Increases Methylation [8]
Adhesion G protein-coupled receptor L2 (ADGRL2) OTCXD2YR AGRL2_HUMAN Decreases Methylation [8]
Solute carrier family 2, facilitated glucose transporter member 10 (SLC2A10) OTL32QH7 GTR10_HUMAN Decreases Methylation [8]
Apoptosis-inducing factor 1, mitochondrial (AIFM1) OTKPWB7Q AIFM1_HUMAN Decreases Methylation [8]
Zinc finger protein SNAI1 (SNAI1) OTDPYAMC SNAI1_HUMAN Increases Expression [10]
Phosphatidylserine lipase ABHD16A (ABHD16A) OTDS9K1Z ABHGA_HUMAN Increases Methylation [8]
Uncharacterized protein C6orf47 (C6ORF47) OTMKBNDD CF047_HUMAN Increases Methylation [8]
One cut domain family member 2 (ONECUT2) OTHUE5YY ONEC2_HUMAN Increases Methylation [8]
Cholesterol 25-hydroxylase (CH25H) OT9S2BSW CH25H_HUMAN Increases Methylation [8]
Securin (PTTG1) OTIMYS4W PTTG1_HUMAN Decreases Expression [22]
G1/S-specific cyclin-E2 (CCNE2) OTBBUKQQ CCNE2_HUMAN Decreases Expression [9]
Aspartate aminotransferase, mitochondrial (GOT2) OT6XBWN0 AATM_HUMAN Increases Methylation [8]
Adenosine deaminase (ADA) OTOX2872 ADA_HUMAN Decreases Methylation [8]
Complement C3 (C3) OTCH5GS0 CO3_HUMAN Decreases Expression [10]
Pro-epidermal growth factor (EGF) OTANRJ0L EGF_HUMAN Affects Activity [23]
Protransforming growth factor alpha (TGFA) OTPD1LL9 TGFA_HUMAN Increases Expression [10]
Transforming growth factor beta-1 proprotein (TGFB1) OTV5XHVH TGFB1_HUMAN Increases Expression [24]
Prolactin (PRL) OTWFQGX7 PRL_HUMAN Decreases Secretion [25]
Interleukin-1 beta (IL1B) OT0DWXXB IL1B_HUMAN Increases Expression [26]
Complement component C9 (C9) OT7I5FDX CO9_HUMAN Increases Methylation [8]
Lactotransferrin (LTF) OT8JWCZ0 TRFL_HUMAN Increases Expression [10]
Estrogen receptor (ESR1) OTKLU61J ESR1_HUMAN Decreases Expression [27]
Glucocorticoid receptor (NR3C1) OTCI2YDI GCR_HUMAN Increases Expression [10]
Trefoil factor 1 (TFF1) OTCYQH4F TFF1_HUMAN Decreases Expression [28]
Cellular tumor antigen p53 (TP53) OTIE1VH3 P53_HUMAN Decreases Expression [29]
Non-histone chromosomal protein HMG-14 (HMGN1) OTSMGH99 HMGN1_HUMAN Decreases Methylation [8]
Plasminogen activator inhibitor 2 (SERPINB2) OT72QLZB PAI2_HUMAN Increases Expression [26]
Interleukin-6 (IL6) OTUOSCCU IL6_HUMAN Increases Expression [26]
Keratin, type I cytoskeletal 18 (KRT18) OTVLQFIP K1C18_HUMAN Increases Methylation [8]
Tyrosine-protein kinase Lck (LCK) OT883FG9 LCK_HUMAN Increases Methylation [8]
Retinoblastoma-associated protein (RB1) OTQJUJMZ RB_HUMAN Decreases Phosphorylation [30]
Progesterone receptor (PGR) OT0FZ3QE PRGR_HUMAN Decreases Expression [31]
Cyclin-dependent kinase 1 (CDK1) OTW1SC2N CDK1_HUMAN Decreases Expression [9]
ATP synthase subunit beta, mitochondrial (ATP5F1B) OTLFZUQK ATPB_HUMAN Increases Expression [32]
Complement C2 (C2) OTHMF4YM CO2_HUMAN Increases Methylation [8]
Lipoprotein lipase (LPL) OTTW0267 LIPL_HUMAN Decreases Expression [10]
Neurofilament medium polypeptide (NEFM) OT8VCBNF NFM_HUMAN Increases Methylation [8]
Thyroid peroxidase (TPO) OTJJLL20 PERT_HUMAN Increases Methylation [8]
Prostate-specific antigen (KLK3) OTFGSBFJ KLK3_HUMAN Decreases Expression [10]
Cathepsin D (CTSD) OTQZ36F3 CATD_HUMAN Decreases Expression [28]
Heat shock protein HSP 90-alpha (HSP90AA1) OTLG1WPK HS90A_HUMAN Increases Expression [10]
Tyrosine-protein kinase Lyn (LYN) OTP686K2 LYN_HUMAN Increases Methylation [8]
Thrombospondin-1 (THBS1) OT0ECWK3 TSP1_HUMAN Increases Expression [10]
Insulin-like growth factor 1 receptor (IGF1R) OTXJIF13 IGF1R_HUMAN Increases Phosphorylation [33]
ATP-dependent translocase ABCB1 (ABCB1) OTEJROBO MDR1_HUMAN Increases Expression [34]
Insulin-like growth factor-binding protein 1 (IGFBP1) OT6UQV2K IBP1_HUMAN Increases Expression [10]
Galectin-1 (LGALS1) OT8LDFWR LEG1_HUMAN Increases Expression [10]
Heme oxygenase 1 (HMOX1) OTC1W6UX HMOX1_HUMAN Decreases Expression [26]
Granulocyte colony-stimulating factor (CSF3) OT9GC6TP CSF3_HUMAN Decreases Expression [26]
Histone H2A.Z (H2AZ1) OT3KJJNQ H2AZ_HUMAN Decreases Expression [35]
Protein RD3-like (RD3L) OTLV3BU0 RD3L_HUMAN Increases Methylation [8]
Granzyme B (GZMB) OTPPVIRS GRAB_HUMAN Decreases Expression [24]
Interleukin-8 (CXCL8) OTS7T5VH IL8_HUMAN Increases Expression [26]
Lysosomal alpha-glucosidase (GAA) OT03PU29 LYAG_HUMAN Increases Methylation [8]
Androgen receptor (AR) OTUBKAZZ ANDR_HUMAN Decreases Expression [31]
Retinoic acid receptor alpha (RARA) OT192V9V RARA_HUMAN Decreases Expression [10]
Osteopontin (SPP1) OTJGC23Y OSTP_HUMAN Increases Expression [10]
Nuclear receptor subfamily 2 group F member 6 (NR2F6) OTNVO2B6 NR2F6_HUMAN Increases Expression [10]
Transforming growth factor beta-3 proprotein (TGFB3) OT2LOUQ1 TGFB3_HUMAN Decreases Expression [10]
Microtubule-associated protein tau (MAPT) OTMTP2Z7 TAU_HUMAN Decreases Expression [36]
Mast/stem cell growth factor receptor Kit (KIT) OTHUY3VZ KIT_HUMAN Increases Methylation [8]
Ras-related protein Ral-A (RALA) OT734R7X RALA_HUMAN Increases Expression [10]
Spectrin beta chain, erythrocytic (SPTB) OT1Q9ABM SPTB1_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase pim-1 (PIM1) OTWEKXTU PIM1_HUMAN Increases Expression [26]
Glucose-6-phosphate 1-dehydrogenase (G6PD) OT300SMK G6PD_HUMAN Increases Expression [10]
Steroid hormone receptor ERR1 (ESRRA) OTTDTUSP ERR1_HUMAN Increases Expression [32]
Aromatase (CYP19A1) OTZ6XF74 CP19A_HUMAN Increases Expression [10]
Dystrophin (DMD) OTD21T5J DMD_HUMAN Decreases Methylation [8]
Collagen alpha-2(VI) chain (COL6A2) OTQC6PPO CO6A2_HUMAN Increases Methylation [8]
Creatine kinase B-type (CKB) OTUCKOTT KCRB_HUMAN Increases Expression [10]
Bone morphogenetic protein 4 (BMP4) OTPZMDFH BMP4_HUMAN Increases Expression [10]
Nuclear receptor subfamily 2 group C member 1 (NR2C1) OTJEL7WT NR2C1_HUMAN Increases Methylation [8]
Gamma-interferon-inducible lysosomal thiol reductase (IFI30) OT9DERT1 GILT_HUMAN Decreases Methylation [8]
C-C motif chemokine 2 (CCL2) OTAD2HEL CCL2_HUMAN Increases Expression [10]
3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1 (HSD3B1) OTNAZVKB 3BHS1_HUMAN Increases Methylation [8]
Perforin-1 (PRF1) OTFVXD7H PERF_HUMAN Decreases Expression [24]
Interleukin-1 receptor type 1 (IL1R1) OTTU8959 IL1R1_HUMAN Increases Methylation [8]
Matrix metalloproteinase-9 (MMP9) OTB2QDAV MMP9_HUMAN Increases Expression [10]
Junction plakoglobin (JUP) OTUH7VMO PLAK_HUMAN Increases Methylation [8]
Nucleoside diphosphate kinase A (NME1) OT0NELQ1 NDKA_HUMAN Decreases Expression [9]
Transcription factor 4 (TCF4) OTB9ASTK ITF2_HUMAN Increases Methylation [8]
Platelet-derived growth factor receptor alpha (PDGFRA) OTDJXUCN PGFRA_HUMAN Decreases Methylation [8]
Carboxypeptidase E (CPE) OTXNTV79 CBPE_HUMAN Increases Methylation [8]
Transcription factor JunB (JUNB) OTG2JXV5 JUNB_HUMAN Increases Expression [10]
Gap junction alpha-1 protein (GJA1) OTT94MKL CXA1_HUMAN Decreases Expression [37]
Creatine kinase S-type, mitochondrial (CKMT2) OT1KNPI1 KCRS_HUMAN Increases Methylation [8]
Insulin-like growth factor-binding protein 3 (IGFBP3) OTIX63TX IBP3_HUMAN Increases Methylation [8]
Bone morphogenetic protein 7 (BMP7) OTYATP2K BMP7_HUMAN Increases Expression [10]
Inter-alpha-trypsin inhibitor heavy chain H1 (ITIH1) OTSXJGQF ITIH1_HUMAN Increases Methylation [8]
C-X-C motif chemokine 3 (CXCL3) OTSL94KH CXCL3_HUMAN Increases Expression [26]
Follistatin (FST) OTRIVK9Y FST_HUMAN Increases Expression [26]
Gastricsin (PGC) OTQRITKI PEPC_HUMAN Increases Methylation [8]
B-cell receptor CD22 (CD22) OTXDJR9T CD22_HUMAN Increases Methylation [8]
T-cell surface glycoprotein CD3 zeta chain (CD247) OT45FGUX CD3Z_HUMAN Increases Methylation [8]
Cytoplasmic aconitate hydratase (ACO1) OT2VUR7L ACOHC_HUMAN Increases Methylation [8]
Receptor tyrosine-protein kinase erbB-3 (ERBB3) OTRSST0A ERBB3_HUMAN Decreases Expression [10]
Catechol O-methyltransferase (COMT) OTPWKTQG COMT_HUMAN Increases Expression [10]
Tenascin-X (TNXB) OTVBWAV5 TENX_HUMAN Increases Methylation [8]
Fibulin-1 (FBLN1) OT5MHHOP FBLN1_HUMAN Increases Methylation [8]
Transcription elongation factor A protein 1 (TCEA1) OTBFO594 TCEA1_HUMAN Decreases Methylation [8]
Cerebellin-1 (CBLN1) OTIXFRAG CBLN1_HUMAN Increases Methylation [8]
Brain-derived neurotrophic factor (BDNF) OTLGH7EW BDNF_HUMAN Increases Expression [10]
G1/S-specific cyclin-D1 (CCND1) OT8HPTKJ CCND1_HUMAN Decreases Expression [27]
Insulin-like growth factor-binding protein 5 (IGFBP5) OTRE5V0C IBP5_HUMAN Increases Expression [10]
G1/S-specific cyclin-E1 (CCNE1) OTLD7UID CCNE1_HUMAN Decreases Expression [38]
Cyclin-dependent kinase 2 (CDK2) OTB5DYYZ CDK2_HUMAN Increases Expression [38]
Endothelin-1 receptor (EDNRA) OTK9T5O3 EDNRA_HUMAN Increases Methylation [8]
Atypical chemokine receptor 3 (ACKR3) OTA6GA4F ACKR3_HUMAN Decreases Methylation [8]
NF-kappa-B inhibitor alpha (NFKBIA) OTFT924M IKBA_HUMAN Decreases Expression [26]
Integrin beta-7 (ITGB7) OT33UUKU ITB7_HUMAN Increases Methylation [8]
DNA cytosine-5)-methyltransferase 1 (DNMT1) OTM2DGTK DNMT1_HUMAN Decreases Expression [9]
NKG2-C type II integral membrane protein (KLRC2) OTT4N86S NKG2C_HUMAN Increases Methylation [8]
Beta-crystallin B3 (CRYBB3) OTTGTQIQ CRBB3_HUMAN Decreases Methylation [8]
Mitogen-activated protein kinase 3 (MAPK3) OTCYKGKO MK03_HUMAN Increases Phosphorylation [39]
Proteasome subunit beta type-8 (PSMB8) OTW5XGMF PSB8_HUMAN Increases Methylation [8]
Choline O-acetyltransferase (CHAT) OTEJWQ45 CLAT_HUMAN Increases Methylation [8]
Gamma-aminobutyric acid receptor subunit rho-2 (GABRR2) OTLDLU1S GBRR2_HUMAN Increases Methylation [8]
Mitogen-activated protein kinase 1 (MAPK1) OTH85PI5 MK01_HUMAN Increases Phosphorylation [39]
CCN family member 2 (CCN2) OTC39NSU CCN2_HUMAN Increases Expression [10]
Lysine-specific demethylase 5A (KDM5A) OTLYFX8A KDM5A_HUMAN Increases Methylation [8]
Leukocyte tyrosine kinase receptor (LTK) OT4GPX7K LTK_HUMAN Decreases Methylation [8]
Transmembrane 4 L6 family member 1 (TM4SF1) OTY0ECQN T4S1_HUMAN Increases Methylation [8]
Adenosine receptor A1 (ADORA1) OTI7X39E AA1R_HUMAN Decreases Expression [10]
Fibroblast growth factor 9 (FGF9) OT2SKDGM FGF9_HUMAN Decreases Expression [40]
Sodium- and chloride-dependent taurine transporter (SLC6A6) OT67U7G3 SC6A6_HUMAN Increases Methylation [8]
Gamma-aminobutyric acid receptor subunit alpha-5 (GABRA5) OTBIKWQT GBRA5_HUMAN Decreases Methylation [8]
DnaJ homolog subfamily A member 1 (DNAJA1) OT38BZQQ DNJA1_HUMAN Increases Methylation [8]
3-hydroxyisobutyrate dehydrogenase, mitochondrial (HIBADH) OTCMMMIZ 3HIDH_HUMAN Increases Methylation [8]
Neural cell adhesion molecule L1 (L1CAM) OTNWAQ4Y L1CAM_HUMAN Increases Expression [10]
CD70 antigen (CD70) OTHB2AL1 CD70_HUMAN Increases Methylation [8]
Long-chain-fatty-acid--CoA ligase 1 (ACSL1) OTB06ESI ACSL1_HUMAN Increases Methylation [8]
Cytochrome P450 2C18 (CYP2C18) OTY687L9 CP2CI_HUMAN Increases Methylation [8]
Protein S100-A5 (S100A5) OTCGGL6K S10A5_HUMAN Increases Expression [10]
Protein S100-A3 (S100A3) OTVIZJ2R S10A3_HUMAN Increases Methylation [8]
Dual specificity protein kinase TTK (TTK) OTBY1Z5H TTK_HUMAN Decreases Expression [9]
Prostaglandin G/H synthase 2 (PTGS2) OT75U9M4 PGH2_HUMAN Increases Expression [10]
Nuclear receptor ROR-alpha (RORA) OTGQT12P RORA_HUMAN Increases Methylation [8]
Sodium channel protein type 1 subunit alpha (SCN1A) OTJ9ZTYI SCN1A_HUMAN Increases Methylation [8]
Hepatocyte nuclear factor 1-beta (HNF1B) OTSYIC3T HNF1B_HUMAN Decreases Expression [41]
Transcription factor SOX-6 (SOX6) OTT0W0LE SOX6_HUMAN Increases Methylation [8]
Aryl hydrocarbon receptor (AHR) OTFE4EYE AHR_HUMAN Increases Expression [10]
Receptor-type tyrosine-protein kinase FLT3 (FLT3) OTMSRYMK FLT3_HUMAN Increases Methylation [8]
Breast cancer type 1 susceptibility protein (BRCA1) OT5BN6VH BRCA1_HUMAN Decreases Expression [27]
Collagen alpha-1(XVIII) chain (COL18A1) OTJFUH6O COIA1_HUMAN Increases Methylation [8]
Pre-B-cell leukemia transcription factor 3 (PBX3) OT8WMVM4 PBX3_HUMAN Increases Methylation [8]
Glutamate receptor 3 (GRIA3) OT34CNBR GRIA3_HUMAN Decreases Methylation [8]
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform (PIK3CB) OTO8JQJA PK3CB_HUMAN Increases Methylation [8]
Phosphatidylinositol 4-kinase alpha (PI4KA) OT2L2G6C PI4KA_HUMAN Increases Methylation [8]
Dipeptidyl aminopeptidase-like protein 6 (DPP6) OTWW3H0K DPP6_HUMAN Decreases Methylation [8]
Tyrosine-protein kinase Tec (TEC) OTU6QJAJ TEC_HUMAN Increases Methylation [8]
Condensin-2 complex subunit D3 (NCAPD3) OTOZY2UL CNDD3_HUMAN Increases Methylation [8]
Cathepsin O (CTSO) OTFL6VRO CATO_HUMAN Increases Expression [10]
Aldehyde dehydrogenase family 3 member B1 (ALDH3B1) OT5NEUQE AL3B1_HUMAN Increases Methylation [8]
Tumor necrosis factor receptor superfamily member 4 (TNFRSF4) OTDK74C0 TNR4_HUMAN Decreases Methylation [8]
Neuronal acetylcholine receptor subunit alpha-4 (CHRNA4) OT1H0ZXC ACHA4_HUMAN Increases Methylation [8]
Cyclin-dependent kinase inhibitor 1B (CDKN1B) OTNY5LLZ CDN1B_HUMAN Increases Expression [30]
5-hydroxytryptamine receptor 5A (HTR5A) OTRKPCQV 5HT5A_HUMAN Increases Methylation [8]
Tumor necrosis factor ligand superfamily member 6 (FASLG) OTZARCHH TNFL6_HUMAN Decreases Methylation [8]
G protein-activated inward rectifier potassium channel 2 (KCNJ6) OTDE1FT0 KCNJ6_HUMAN Increases Methylation [8]
Retinoic acid receptor RXR-gamma (RXRG) OT254B09 RXRG_HUMAN Decreases Methylation [8]
Nuclear receptor-interacting protein 1 (NRIP1) OTIZOJQV NRIP1_HUMAN Decreases Expression [10]
Protein PRRC2A (PRRC2A) OTBX6FM5 PRC2A_HUMAN Increases Methylation [8]
Protein farnesyltransferase subunit beta (CHURC1-FNTB) OT34M7E3 FNTB_HUMAN Increases Methylation [8]
Protein phosphatase 1F (PPM1F) OTU0MVR7 PPM1F_HUMAN Increases Methylation [8]
Casein kinase I isoform epsilon (CSNK1E) OTF0UXX6 KC1E_HUMAN Increases Methylation [8]
CCAAT/enhancer-binding protein delta (CEBPD) OTNBIPMY CEBPD_HUMAN Increases Methylation [8]
Nuclear pore complex protein Nup153 (NUP153) OTCAS0AR NU153_HUMAN Increases Methylation [8]
Protein Tob1 (TOB1) OTNW949D TOB1_HUMAN Increases Methylation [8]
Lipopolysaccharide-responsive and beige-like anchor protein (LRBA) OTOUZN9G LRBA_HUMAN Increases Methylation [8]
Transcription activator BRG1 (SMARCA4) OT68WOPQ SMCA4_HUMAN Decreases Expression [29]
Nuclear receptor subfamily 0 group B member 1 (NR0B1) OTC8P9GN NR0B1_HUMAN Increases Expression [10]
Serine/threonine-protein kinase Nek2 (NEK2) OT1H27HO NEK2_HUMAN Decreases Expression [9]
Beta-chimaerin (CHN2) OTSSDPWN CHIO_HUMAN Increases Methylation [8]
Ephrin-A5 (EFNA5) OTOH4DRR EFNA5_HUMAN Increases Expression [10]
Stanniocalcin-1 (STC1) OTGVVXYF STC1_HUMAN Decreases Methylation [8]
Ataxin-1 (ATXN1) OTQF0HNR ATX1_HUMAN Increases Methylation [8]
Huntingtin-associated protein 1 (HAP1) OT6SG0JQ HAP1_HUMAN Increases Methylation [8]
Myomesin-2 (MYOM2) OTD2UOXW MYOM2_HUMAN Increases Methylation [8]
Tyrosine-protein phosphatase non-receptor type 5 (PTPN5) OT2H1KDK PTN5_HUMAN Increases Methylation [8]
Protein AF-10 (MLLT10) OTURMDV7 AF10_HUMAN Increases Methylation [8]
Adenosine kinase (ADK) OTXR6VDI ADK_HUMAN Increases Methylation [8]
Hepatocyte nuclear factor 3-alpha (FOXA1) OTEBY0TD FOXA1_HUMAN Increases Expression [10]
Galectin-4 (LGALS4) OTKQCG0H LEG4_HUMAN Increases Methylation [8]
Histone deacetylase 4 (HDAC4) OTQNGD32 HDAC4_HUMAN Increases Methylation [8]
Claudin-17 (CLDN17) OTQCEYBY CLD17_HUMAN Decreases Methylation [8]
Breast cancer anti-estrogen resistance protein 1 (BCAR1) OTKT2C2N BCAR1_HUMAN Increases Expression [10]
Pro-neuregulin-3, membrane-bound isoform (NRG3) OTIFZ5CT NRG3_HUMAN Increases Methylation [8]
Claudin-2 (CLDN2) OTRF3D6Y CLD2_HUMAN Decreases Methylation [8]
Neurexin-1-beta (NRXN1) OTJN1JQA NRX1B_HUMAN Decreases Methylation [8]
CD81 antigen (CD81) OTQFXNAZ CD81_HUMAN Increases Methylation [8]
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN (PTEN) OTOWDUNT PTEN_HUMAN Increases Methylation [8]
26S proteasome complex subunit SEM1 (SEM1) OTASLBM1 SEM1_HUMAN Decreases Methylation [8]
Protein max (MAX) OTKZ0YKM MAX_HUMAN Increases Methylation [8]
Small ribosomal subunit protein eS7 (RPS7) OTIK25WI RS7_HUMAN Increases Methylation [8]
Small nuclear ribonucleoprotein G (SNRPG) OTWX4XK1 RUXG_HUMAN Increases Methylation [8]
DNA-directed RNA polymerases I, II, and III subunit RPABC5 (POLR2L) OTSSOMUP RPAB5_HUMAN Decreases Methylation [8]
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform (PPP2R2A) OT9297OG 2ABA_HUMAN Increases Methylation [8]
Inward rectifier potassium channel 2 (KCNJ2) OT2OQEZS KCNJ2_HUMAN Decreases Methylation [8]
Tropomyosin alpha-4 chain (TPM4) OTN4YLYR TPM4_HUMAN Increases Methylation [8]
Actin, alpha skeletal muscle (ACTA1) OTOVGLPG ACTS_HUMAN Increases Methylation [8]
Reelin (RELN) OTLKMW1O RELN_HUMAN Increases Methylation [8]
C-C motif chemokine 20 (CCL20) OTUCJY4N CCL20_HUMAN Increases Expression [26]
Small ribosomal subunit protein uS9m (MRPS9) OTD4XOHS RT09_HUMAN Decreases Methylation [8]
Mothers against decapentaplegic homolog 3 (SMAD3) OTNA96MR SMAD3_HUMAN Increases Methylation [8]
Calcium-transporting ATPase type 2C member 1 (ATP2C1) OTQN51T3 AT2C1_HUMAN Affects Methylation [8]
Phospholipid-transporting ATPase IH (ATP11A) OT7M9ZDK AT11A_HUMAN Increases Methylation [8]
Cytochrome c (CYCS) OTBFALJD CYC_HUMAN Increases Expression [32]
Cyclin-dependent kinase 6 (CDK6) OTR95N0X CDK6_HUMAN Increases Expression [29]
Transcription factor E2F1 (E2F1) OTLKYBBC E2F1_HUMAN Decreases Expression [38]
Runt-related transcription factor 1 (RUNX1) OTU7J84H RUNX1_HUMAN Decreases Methylation [8]
Hydroxymethylglutaryl-CoA synthase, cytoplasmic (HMGCS1) OTCO26FV HMCS1_HUMAN Increases Methylation [8]
ATP-dependent 6-phosphofructokinase, platelet type (PFKP) OTFP7AA8 PFKAP_HUMAN Increases Methylation [8]
DNA-binding protein SATB1 (SATB1) OTT7SUVW SATB1_HUMAN Decreases Methylation [8]
Zinc finger protein basonuclin-1 (BNC1) OTGJ5WUF BNC1_HUMAN Decreases Methylation [8]
Inactive tyrosine-protein kinase transmembrane receptor ROR1 (ROR1) OTEUYEW6 ROR1_HUMAN Increases Methylation [8]
2-oxoglutarate dehydrogenase complex component E1 (OGDH) OTHGTQWF ODO1_HUMAN Increases Methylation [8]
Pro-neuregulin-1, membrane-bound isoform (NRG1) OTZO6F1X NRG1_HUMAN Increases Methylation [8]
Dystonin (DST) OTHZBM4X DYST_HUMAN Increases Methylation [8]
Caveolin-1 (CAV1) OTEZUR1L CAV1_HUMAN Decreases Expression [10]
Trefoil factor 2 (TFF2) OTRXB19X TFF2_HUMAN Decreases Expression [42]
Early growth response protein 4 (EGR4) OT4R3ECK EGR4_HUMAN Increases Methylation [8]
Focal adhesion kinase 1 (PTK2) OT3Q1JDY FAK1_HUMAN Increases Degradation [39]
Homeobox protein engrailed-1 (EN1) OT2DKIDK HME1_HUMAN Decreases Methylation [8]
Recombining binding protein suppressor of hairless (RBPJ) OTD7CUG0 SUH_HUMAN Increases Methylation [8]
DNA repair protein RAD51 homolog 1 (RAD51) OTNVWGC1 RAD51_HUMAN Decreases Expression [9]
Collagen alpha-1(XVI) chain (COL16A1) OTOWKUO2 COGA1_HUMAN Increases Methylation [8]
Trichohyalin (TCHH) OT4J7EFT TRHY_HUMAN Decreases Methylation [8]
Forkhead box protein M1 (FOXM1) OT5887KR FOXM1_HUMAN Decreases Expression [9]
3',5'-cyclic-AMP phosphodiesterase 4D (PDE4D) OT1RWFV0 PDE4D_HUMAN Decreases Methylation [8]
Transmembrane protein 62 (TMEM62) OTJ4SPCM TMM62_HUMAN Increases Methylation [8]
General transcription factor 3C polypeptide 1 (GTF3C1) OT7JK0RG TF3C1_HUMAN Increases Methylation [8]
Calcium-activated potassium channel subunit alpha-1 (KCNMA1) OTNYXOZO KCMA1_HUMAN Increases Methylation [8]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1 (SMARCB1) OT2LP7LJ SNF5_HUMAN Increases Expression [29]
Cell division cycle protein 20 homolog (CDC20) OTCOEZRV CDC20_HUMAN Decreases Expression [9]
Follistatin-related protein 1 (FSTL1) OT6KEZUD FSTL1_HUMAN Increases Methylation [8]
Splicing factor, suppressor of white-apricot homolog (SFSWAP) OT7H3ETA SFSWA_HUMAN Increases Methylation [8]
Heat shock protein 75 kDa, mitochondrial (TRAP1) OTNG0L8J TRAP1_HUMAN Increases Methylation [8]
Ankyrin-3 (ANK3) OTJ3IRBP ANK3_HUMAN Increases Methylation [8]
BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 (BNIP2) OTVZD4H6 BNIP2_HUMAN Increases Methylation [8]
Interleukin-24 (IL24) OT4VUWH1 IL24_HUMAN Increases Expression [26]
Semaphorin-3B (SEMA3B) OTCZCPMS SEM3B_HUMAN Increases Methylation [8]
Mitotic spindle assembly checkpoint protein MAD2A (MAD2L1) OTXNGZCG MD2L1_HUMAN Decreases Expression [9]
Growth factor receptor-bound protein 10 (GRB10) OTCKXGRC GRB10_HUMAN Increases Methylation [8]
Metastasis-associated protein MTA1 (MTA1) OTBHW3S9 MTA1_HUMAN Decreases Expression [10]
C-terminal-binding protein 1 (CTBP1) OTVYH2DH CTBP1_HUMAN Decreases Expression [10]
Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9) OT70Z4II ADAM9_HUMAN Increases Methylation [8]
snRNA-activating protein complex subunit 2 (SNAPC2) OTN0EL6L SNPC2_HUMAN Increases Methylation [8]
Baculoviral IAP repeat-containing protein 3 (BIRC3) OT3E95KB BIRC3_HUMAN Increases Methylation [8]
Phosphatidylinositol-binding clathrin assembly protein (PICALM) OTQVRPMQ PICAL_HUMAN Increases Methylation [8]
Mastermind-like domain-containing protein 1 (MAMLD1) OT9EVMQY MAMD1_HUMAN Decreases Methylation [8]
Solute carrier family 12 member 1 (SLC12A1) OT6YSX0G S12A1_HUMAN Decreases Methylation [8]
Dual specificity tyrosine-phosphorylation-regulated kinase 1A (DYRK1A) OTPLXCDN DYR1A_HUMAN Decreases Methylation [8]
Protein patched homolog 1 (PTCH1) OTMG07H5 PTC1_HUMAN Increases Expression [10]
Nuclear receptor coactivator 4 (NCOA4) OTRVU0UA NCOA4_HUMAN Increases Methylation [8]
ADP-ribosylation factor-related protein 1 (ARFRP1) OTP1OV78 ARFRP_HUMAN Increases Methylation [8]
Protein Shroom2 (SHROOM2) OTZ2FJ7Q SHRM2_HUMAN Increases Methylation [8]
Beta-1-syntrophin (SNTB1) OTSRBECI SNTB1_HUMAN Decreases Methylation [8]
Nuclear nucleic acid-binding protein C1D (C1D) OTI9PMN1 C1D_HUMAN Decreases Methylation [8]
Voltage-dependent L-type calcium channel subunit alpha-1C (CACNA1C) OT6KFNMS CAC1C_HUMAN Increases Methylation [8]
Nidogen-2 (NID2) OTHC33FF NID2_HUMAN Increases Methylation [8]
Protein FAM53B (FAM53B) OTVD7OU6 FA53B_HUMAN Decreases Methylation [8]
Four and a half LIM domains protein 2 (FHL2) OT0OAYWT FHL2_HUMAN Increases Methylation [8]
Dihydropyrimidinase-related protein 3 (DPYSL3) OTINJV20 DPYL3_HUMAN Increases Methylation [8]
Cytoplasmic dynein 1 heavy chain 1 (DYNC1H1) OTD1KRKO DYHC1_HUMAN Increases Methylation [8]
Elongin-A (ELOA) OTOQTF5K ELOA1_HUMAN Increases Methylation [8]
Filamin-C (FLNC) OT3F8J6Y FLNC_HUMAN Decreases Methylation [8]
Histone RNA hairpin-binding protein (SLBP) OTVYYQRT SLBP_HUMAN Decreases Methylation [8]
Inositol 1,4,5-trisphosphate receptor type 2 (ITPR2) OTPHGZ19 ITPR2_HUMAN Increases Methylation [8]
Indian hedgehog protein (IHH) OT1DWGXC IHH_HUMAN Decreases Methylation [8]
Separin (ESPL1) OTMGEVOK ESPL1_HUMAN Decreases Expression [9]
Disco-interacting protein 2 homolog A (DIP2A) OTXPTR8R DIP2A_HUMAN Decreases Methylation [8]
Latent-transforming growth factor beta-binding protein 1 (LTBP1) OTR7Q75L LTBP1_HUMAN Decreases Expression [10]
LIM and SH3 domain protein 1 (LASP1) OT2QIDCL LASP1_HUMAN Increases Methylation [8]
Sodium/hydrogen exchanger 5 (SLC9A5) OTM70CXN SL9A5_HUMAN Decreases Methylation [8]
Protein disulfide-isomerase A6 (PDIA6) OT8YBR17 PDIA6_HUMAN Increases Methylation [8]
Inactive phospholipase C-like protein 1 (PLCL1) OTJL2C79 PLCL1_HUMAN Decreases Methylation [8]
Cyclin-dependent kinase 10 (CDK10) OTKP7TTR CDK10_HUMAN Increases Methylation [8]
Plectin (PLEC) OTU4XDEG PLEC_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase 38 (STK38) OTKMYCYR STK38_HUMAN Increases Methylation [8]
RalA-binding protein 1 (RALBP1) OTBIGB1D RBP1_HUMAN Increases Methylation [8]
Ribosomal protein S6 kinase alpha-2 (RPS6KA2) OTIOYUSU KS6A2_HUMAN Decreases Methylation [8]
Scaffold attachment factor B1 (SAFB) OTGRV2LW SAFB1_HUMAN Increases Methylation [8]
Nuclear receptor subfamily 0 group B member 2 (NR0B2) OT7UVICX NR0B2_HUMAN Decreases Expression [10]
Nuclear receptor coactivator 2 (NCOA2) OTMQFPBB NCOA2_HUMAN Increases Expression [10]
Olfactory receptor 1C1 (OR1C1) OT9WTEX5 OR1C1_HUMAN Decreases Methylation [8]
Mediator of RNA polymerase II transcription subunit 1 (MED1) OTOO24C4 MED1_HUMAN Decreases Expression [10]
ETS-related transcription factor Elf-2 (ELF2) OTEI347F ELF2_HUMAN Increases Methylation [8]
NGFI-A-binding protein 2 (NAB2) OTG4BDF3 NAB2_HUMAN Increases Expression [10]
Nuclear receptor coactivator 1 (NCOA1) OTLIUJQD NCOA1_HUMAN Increases Expression [10]
Glutamate receptor ionotropic, kainate 4 (GRIK4) OTL5EIPA GRIK4_HUMAN Decreases Methylation [8]
NT-3 growth factor receptor (NTRK3) OTII30MY NTRK3_HUMAN Increases Methylation [8]
Meprin A subunit alpha (MEP1A) OTY2Z48T MEP1A_HUMAN Increases Methylation [8]
Receptor-type tyrosine-protein phosphatase O (PTPRO) OTFLKWOY PTPRO_HUMAN Increases Methylation [8]
Cysteine dioxygenase type 1 (CDO1) OTLG1P77 CDO1_HUMAN Decreases Methylation [8]
Protein inscuteable homolog (INSC) OTP16ERR INSC_HUMAN Increases Methylation [8]
Inverted formin-2 (INF2) OT8ZM13C INF2_HUMAN Increases Methylation [8]
Transmembrane protein 266 (TMEM266) OTM17VHD TM266_HUMAN Increases Methylation [8]
ATP-binding cassette sub-family B member 5 (ABCB5) OT8AKP1J ABCB5_HUMAN Increases Methylation [8]
CST complex subunit CTC1 (CTC1) OTRJY7QD CTC1_HUMAN Decreases Methylation [8]
FH1/FH2 domain-containing protein 3 (FHOD3) OT1WUBQX FHOD3_HUMAN Decreases Methylation [8]
Carcinoembryonic antigen-related cell adhesion molecule 16 (CEACAM16) OTUMUSY0 CEA16_HUMAN Increases Methylation [8]
Leucine-rich repeat flightless-interacting protein 1 (LRRFIP1) OTN7XAUD LRRF1_HUMAN Decreases Methylation [8]
Polycomb group RING finger protein 3 (PCGF3) OTY7TPPZ PCGF3_HUMAN Increases Methylation [8]
MAP7 domain-containing protein 1 (MAP7D1) OTMGC8N9 MA7D1_HUMAN Decreases Methylation [8]
Mucin-like protein 3 (MUCL3) OTGAD3I0 MUCL3_HUMAN Increases Methylation [8]
Cilia- and flagella-associated protein 100 (CFAP100) OTHHFM2Z CP100_HUMAN Increases Methylation [8]
Spermatogenesis-associated serine-rich protein 1 (SPATS1) OTPUXCSA SPAS1_HUMAN Decreases Methylation [8]
Cryptochrome-2 (CRY2) OTERZ93T CRY2_HUMAN Increases Methylation [8]
Ceramide kinase-like protein (CERKL) OTG4YGBR CERKL_HUMAN Decreases Methylation [8]
NAD kinase 2, mitochondrial (NADK2) OT1I8GDE NAKD2_HUMAN Decreases Methylation [8]
Glucoside xylosyltransferase 1 (GXYLT1) OTI5MDYW GXLT1_HUMAN Increases Methylation [8]
Protein GREB1 (GREB1) OTU6ZA26 GREB1_HUMAN Decreases Expression [10]
PAN2-PAN3 deadenylation complex catalytic subunit PAN2 (PAN2) OTB65N2I PAN2_HUMAN Increases Methylation [8]
Acylglycerol kinase, mitochondrial (AGK) OTJGWBYT AGK_HUMAN Increases Methylation [8]
Fibulin-7 (FBLN7) OT1XRDP6 FBLN7_HUMAN Increases Methylation [8]
FRAS1-related extracellular matrix protein 1 (FREM1) OTMHRV87 FREM1_HUMAN Increases Methylation [8]
SH3 domain-containing protein 19 (SH3D19) OTVU3VS2 SH319_HUMAN Increases Methylation [8]
Protein crumbs homolog 2 (CRB2) OTG0L2CE CRUM2_HUMAN Increases Expression [10]
NHL repeat-containing protein 3 (NHLRC3) OTBI6YSN NHLC3_HUMAN Increases Methylation [8]
Dedicator of cytokinesis protein 11 (DOCK11) OTFSTN6A DOC11_HUMAN Increases Methylation [8]
Protein FAM78A (FAM78A) OTDZ36V8 FA78A_HUMAN Decreases Methylation [8]
EF-hand domain-containing protein 1 (EFHC1) OTS9IBNE EFHC1_HUMAN Increases Methylation [8]
Calcium homeostasis modulator protein 4 (CALHM4) OTUDL2HG CAHM4_HUMAN Increases Methylation [8]
Tubulin-specific chaperone cofactor E-like protein (TBCEL) OT2PZLLL TBCEL_HUMAN Increases Methylation [8]
Mucin-21 (MUC21) OTQ8GP5L MUC21_HUMAN Increases Methylation [8]
Uncharacterized protein C6orf132 (C6ORF132) OTMH4S7O CF132_HUMAN Increases Methylation [8]
Calmodulin-regulated spectrin-associated protein 1 (CAMSAP1) OT1N2182 CAMP1_HUMAN Increases Methylation [8]
Uncharacterized protein C1orf185 (C1ORF185) OT32C5NW CA185_HUMAN Increases Methylation [8]
Coiled-coil domain-containing protein 18 (CCDC18) OT0S9DA2 CCD18_HUMAN Decreases Methylation [8]
Growth hormone-regulated TBC protein 1 (GRTP1) OT8HORRZ GRTP1_HUMAN Increases Methylation [8]
Protein sel-1 homolog 2 (SEL1L2) OTSBDWIG SE1L2_HUMAN Increases Methylation [8]
E3 ubiquitin-protein ligase RNF220 (RNF220) OT2FIEXO RN220_HUMAN Increases Methylation [8]
Forkhead box protein B2 (FOXB2) OTJE3RRR FOXB2_HUMAN Increases Methylation [8]
Armadillo repeat-containing protein 3 (ARMC3) OTF6M9MM ARMC3_HUMAN Increases Methylation [8]
Anoctamin-1 (ANO1) OTSREUNI ANO1_HUMAN Increases Methylation [8]
Meteorin-like protein (METRNL) OTB0DDL0 METRL_HUMAN Increases Methylation [8]
DDB1- and CUL4-associated factor 15 (DCAF15) OTWBXZ0E DCA15_HUMAN Increases Methylation [8]
Autophagy-related protein 16-1 (ATG16L1) OTEOYC5D A16L1_HUMAN Increases Methylation [8]
Tensin-3 (TNS3) OTPG2D8Z TENS3_HUMAN Increases Methylation [8]
Coiled-coil domain-containing protein 102B (CCDC102B) OTVDZVD0 C102B_HUMAN Decreases Methylation [8]
Cytosolic phospholipase A2 zeta (PLA2G4F) OT8MUO5U PA24F_HUMAN Increases Methylation [8]
NADH-cytochrome b5 reductase 2 (CYB5R2) OTTLM7XN NB5R2_HUMAN Increases Methylation [8]
Bridge-like lipid transfer protein family member 3A (BLTP3A) OTRLMP17 BLT3A_HUMAN Increases Methylation [8]
Capping protein, Arp2/3 and myosin-I linker protein 2 (CARMIL2) OTV5S1J2 CARL2_HUMAN Increases Methylation [8]
Fatty-acid amide hydrolase 2 (FAAH2) OTS6LX01 FAAH2_HUMAN Decreases Methylation [8]
GRAM domain-containing protein 4 (GRAMD4) OT1HXEPM GRAM4_HUMAN Decreases Methylation [8]
Pleckstrin homology domain-containing family A member 7 (PLEKHA7) OTNUMAZ0 PKHA7_HUMAN Increases Methylation [8]
Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GALNT3) OT6BFB22 B4GN3_HUMAN Decreases Methylation [8]
Teneurin-4 (TENM4) OT91K3FC TEN4_HUMAN Increases Methylation [8]
SANT and BTB domain regulator of class switch recombination (SANBR) OTY7ZODH SANBR_HUMAN Decreases Methylation [8]
Homeobox-containing protein 1 (HMBOX1) OTPKTBVI HMBX1_HUMAN Increases Methylation [8]
TELO2-interacting protein 2 (TTI2) OTU7TQCO TTI2_HUMAN Decreases Methylation [8]
Phostensin (PPP1R18) OT0JVGOZ PPR18_HUMAN Decreases Methylation [8]
Phospholipase B1, membrane-associated (PLB1) OTZ6TTYV PLB1_HUMAN Increases Methylation [8]
Enhancer of mRNA-decapping protein 4 (EDC4) OTBBNIUJ EDC4_HUMAN Increases Methylation [8]
Uncharacterized protein C16orf46 (C16ORF46) OT8FDG3A CP046_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase Nek5 (NEK5) OTHDXCYZ NEK5_HUMAN Increases Methylation [8]
Neuroblastoma breakpoint family member 10 (NBPF10) OTGOCELY NBPFA_HUMAN Affects Methylation [8]
NIPA-like protein 3 (NIPAL3) OTI858LL NPAL3_HUMAN Increases Methylation [8]
Cytochrome b5 domain-containing protein 1 (CYB5D1) OTSZWTPT CB5D1_HUMAN Increases Methylation [8]
E3 ubiquitin-protein ligase RFWD3 (RFWD3) OTDUULBQ RFWD3_HUMAN Decreases Methylation [8]
tRNA methyltransferase 10 homolog B (TRMT10B) OT3EJP6J TM10B_HUMAN Increases Methylation [8]
Kv channel-interacting protein 4 (KCNIP4) OTB1BS0X KCIP4_HUMAN Decreases Methylation [8]
Docking protein 6 (DOK6) OTX55OIF DOK6_HUMAN Affects Methylation [8]
Solute carrier family 25 member 47 (SLC25A47) OT5NGRWC S2547_HUMAN Increases Methylation [8]
SCAN domain-containing protein 3 (SCAND3) OTIIMBQL SCND3_HUMAN Decreases Methylation [8]
Opsin-5 (OPN5) OTCYGHDA OPN5_HUMAN Decreases Methylation [8]
CREB-regulated transcription coactivator 3 (CRTC3) OTVIGVUW CRTC3_HUMAN Increases Methylation [8]
Golgi-associated kinase 1B (GASK1B) OT2HPHEI GAK1B_HUMAN Decreases Methylation [8]
Transmembrane and coiled-coil domain-containing protein 3 (TMCO3) OTYW1KP2 TMCO3_HUMAN Increases Methylation [8]
Protein SNORC (SNORC) OTY3IJK5 SNORC_HUMAN Increases Methylation [8]
Inactive serine protease PAMR1 (PAMR1) OT83ZH5U PAMR1_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase LMTK1 (AATK) OTVHAX5N LMTK1_HUMAN Decreases Methylation [8]
Metastasis-associated in colon cancer protein 1 (MACC1) OTV3DLX0 MACC1_HUMAN Decreases Methylation [8]
Ferric-chelate reductase 1 (FRRS1) OTQDEGEB FRRS1_HUMAN Increases Methylation [8]
Neurobeachin-like protein 2 (NBEAL2) OTMCAXWR NBEL2_HUMAN Increases Methylation [8]
Transmembrane protein 182 (TMEM182) OTVDIS2V TM182_HUMAN Increases Methylation [8]
RING finger protein 207 (RNF207) OT9AYVGV RN207_HUMAN Increases Methylation [8]
Protein ITPRID1 (ITPRID1) OT9MH0BX ITPI1_HUMAN Increases Methylation [8]
Colorectal cancer-associated protein 1 (COLCA1) OT8BP6UD COLC1_HUMAN Decreases Methylation [8]
Protein shisa-6 (SHISA6) OTWBCJ8O SHSA6_HUMAN Decreases Methylation [8]
Major facilitator superfamily domain-containing protein 6 (MFSD6) OTQ6KAV1 MFSD6_HUMAN Increases Methylation [8]
BEN domain-containing protein 4 (BEND4) OT7Z1422 BEND4_HUMAN Increases Methylation [8]
Tumor protein p63-regulated gene 1 protein (TPRG1) OTS48DQM TPRG1_HUMAN Increases Methylation [8]
Phosphoinositide 3-kinase adapter protein 1 (PIK3AP1) OTMW1B47 BCAP_HUMAN Increases Methylation [8]
Coiled-coil domain-containing protein 149 (CCDC149) OT7S7MU9 CC149_HUMAN Decreases Methylation [8]
Cytochrome P450 4V2 (CYP4V2) OTQKNK0D CP4V2_HUMAN Decreases Methylation [8]
MOB kinase activator 2 (MOB2) OTMBE0NS MOB2_HUMAN Affects Methylation [8]
RING finger protein 44 (RNF44) OTGWL4U4 RNF44_HUMAN Increases Methylation [8]
DET1 homolog (DET1) OTHYSDX3 DET1_HUMAN Increases Methylation [8]
MOB kinase activator 1B (MOB1B) OTRE19ZS MOB1B_HUMAN Increases Methylation [8]
Keratin, type I cytoskeletal 26 (KRT26) OTLAXIN0 K1C26_HUMAN Increases Methylation [8]
CUB and sushi domain-containing protein 2 (CSMD2) OT541Z3W CSMD2_HUMAN Increases Methylation [8]
Protein lifeguard 1 (GRINA) OTMC1O66 LFG1_HUMAN Increases Methylation [8]
Podocan (PODN) OTV3P7P5 PODN_HUMAN Increases Methylation [8]
Protein sidekick-1 (SDK1) OTX26906 SDK1_HUMAN Increases Methylation [8]
Ankyrin repeat and sterile alpha motif domain-containing protein 1B (ANKS1B) OT26DGM9 ANS1B_HUMAN Increases Methylation [8]
Transcription factor AP-2-delta (TFAP2D) OT71O6YN AP2D_HUMAN Decreases Methylation [8]
Pleckstrin homology domain-containing family H member 3 (PLEKHH3) OTREOQBO PKHH3_HUMAN Increases Methylation [8]
Cytokine-dependent hematopoietic cell linker (CLNK) OTOWK51S CLNK_HUMAN Decreases Methylation [8]
Calcium/calmodulin-dependent protein kinase II inhibitor 1 (CAMK2N1) OTKCR5XL CK2N1_HUMAN Increases Methylation [8]
Uncharacterized protein C11orf96 (C11ORF96) OTEQU0V7 CK096_HUMAN Increases Methylation [8]
Polypeptide N-acetylgalactosaminyltransferase 5 (GALNT5) OTCV61V1 GALT5_HUMAN Increases Methylation [8]
Pleckstrin homology-like domain family B member 2 (PHLDB2) OTDKMB2G PHLB2_HUMAN Increases Methylation [8]
Protein hinderin (KIAA1328) OT2RMGGB K1328_HUMAN Increases Methylation [8]
TBC1 domain family member 1 (TBC1D1) OTI9V7B0 TBCD1_HUMAN Increases Methylation [8]
Store-operated calcium entry regulator STIMATE (STIMATE) OTEDLKEW STIMA_HUMAN Increases Methylation [8]
Armadillo-like helical domain-containing protein 4 (ARMH4) OT25GBJM ARMD4_HUMAN Increases Methylation [8]
Protein polybromo-1 (PBRM1) OT39WUR9 PB1_HUMAN Decreases Methylation [8]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 2 (MAGI2) OTXDDKZS MAGI2_HUMAN Decreases Methylation [8]
Reticulon-4 receptor-like 1 (RTN4RL1) OTDKKOE7 R4RL1_HUMAN Increases Methylation [8]
Telomerase-binding protein EST1A (SMG6) OTRCEJQL EST1A_HUMAN Increases Methylation [8]
Leucine zipper protein 1 (LUZP1) OTQV3VZM LUZP1_HUMAN Increases Methylation [8]
Serine incorporator 5 (SERINC5) OT3COPVF SERC5_HUMAN Increases Methylation [8]
Myotubularin-related protein 13 (SBF2) OTBB8NO8 MTMRD_HUMAN Increases Methylation [8]
Histone-arginine methyltransferase CARM1 (CARM1) OT0IPRVR CARM1_HUMAN Increases Expression [10]
Ankyrin repeat and LEM domain-containing protein 2 (ANKLE2) OTHCYR6Y ANKL2_HUMAN Increases Methylation [8]
Angiopoietin-related protein 5 (ANGPTL5) OTC6AFVO ANGL5_HUMAN Increases Methylation [8]
Cilium assembly protein DZIP1 (DZIP1) OTBVPO66 DZIP1_HUMAN Increases Methylation [8]
Probable guanine nucleotide exchange factor MCF2L2 (MCF2L2) OTOGFMIH MF2L2_HUMAN Increases Methylation [8]
Protein O-mannosyl-transferase TMTC1 (TMTC1) OTZ7NW96 TMTC1_HUMAN Increases Methylation [8]
Neuron navigator 3 (NAV3) OT97M1TR NAV3_HUMAN Decreases Methylation [8]
Glycerate kinase (GLYCTK) OTVTBNSM GLCTK_HUMAN Increases Methylation [8]
Aprataxin and PNK-like factor (APLF) OTYUR3AH APLF_HUMAN Increases Expression [10]
Adhesion G protein-coupled receptor A3 (ADGRA3) OTPJEV0S AGRA3_HUMAN Increases Methylation [8]
Proton-coupled zinc antiporter SLC30A8 (SLC30A8) OTF0FG5K ZNT8_HUMAN Increases Methylation [8]
Sphingosine-1-phosphate phosphatase 2 (SGPP2) OTIDIJCR SGPP2_HUMAN Increases Methylation [8]
Neuronal PAS domain-containing protein 3 (NPAS3) OT8D1ILB NPAS3_HUMAN Increases Methylation [8]
POU domain class 2-associating factor 2 (POU2AF2) OTPBW3NC OCAT1_HUMAN Increases Methylation [8]
Lamin tail domain-containing protein 2 (LMNTD2) OTKGJ1ST LMTD2_HUMAN Increases Methylation [8]
Nucleotidyltransferase MB21D2 (MB21D2) OT5C4VVU M21D2_HUMAN Increases Methylation [8]
PEX5-related protein (PEX5L) OTLR4HSR PEX5R_HUMAN Decreases Methylation [8]
Proline-, glutamic acid- and leucine-rich protein 1 (PELP1) OTVXQNOT PELP1_HUMAN Decreases Expression [10]
Voltage-dependent calcium channel subunit alpha-2/delta-3 (CACNA2D3) OTEH9HGE CA2D3_HUMAN Increases Methylation [8]
Transcription initiation factor TFIID subunit 1-like (TAF1L) OT9Z7EVA TAF1L_HUMAN Increases Methylation [8]
Leucine-rich repeat LGI family member 2 (LGI2) OTFJ2ZSG LGI2_HUMAN Decreases Methylation [8]
Regulatory-associated protein of mTOR (RPTOR) OT4TQZ9F RPTOR_HUMAN Increases Methylation [8]
UPF0462 protein C4orf33 (C4ORF33) OT3O3FC3 CD033_HUMAN Decreases Methylation [8]
Mesoderm induction early response protein 2 (MIER2) OTYURSWD MIER2_HUMAN Increases Methylation [8]
Xylosyl- and glucuronyltransferase LARGE2 (LARGE2) OT5BZS3J LARG2_HUMAN Increases Methylation [8]
Putative transporter SVOPL (SVOPL) OTJ4G2ND SVOPL_HUMAN Increases Methylation [8]
Follistatin-related protein 5 (FSTL5) OT18C29S FSTL5_HUMAN Decreases Methylation [8]
ADAMTS-like protein 1 (ADAMTSL1) OTBNYF3F ATL1_HUMAN Increases Methylation [8]
EF-hand domain-containing family member B (EFHB) OT83HFEP EFHB_HUMAN Increases Methylation [8]
Protein BANP (BANP) OT1JMTBD BANP_HUMAN Increases Methylation [8]
Sodium-dependent lysophosphatidylcholine symporter 1 (MFSD2A) OTVG1VG0 NLS1_HUMAN Increases Methylation [8]
Kyphoscoliosis peptidase (KY) OTK1L8VX KY_HUMAN Increases Methylation [8]
Clarin-3 (CLRN3) OTZDNL65 CLRN3_HUMAN Increases Methylation [8]
Exophilin-5 (EXPH5) OTOMXDUO EXPH5_HUMAN Decreases Methylation [8]
Nesprin-1 (SYNE1) OTSBSLUH SYNE1_HUMAN Increases Methylation [8]
Metalloreductase STEAP2 (STEAP2) OTGE9ETG STEA2_HUMAN Decreases Methylation [8]
Kelch repeat and BTB domain-containing protein 8 (KBTBD8) OTO8X1UF KBTB8_HUMAN Decreases Methylation [8]
Neuroligin-2 (NLGN2) OTHDYL3H NLGN2_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase Nek11 (NEK11) OTMYENTC NEK11_HUMAN Decreases Methylation [8]
Olfactory receptor 5T1 (OR5T1) OTJT8C6S OR5T1_HUMAN Decreases Methylation [8]
Olfactory receptor 2AK2 (OR2AK2) OTNG4ZS1 O2AK2_HUMAN Increases Methylation [8]
Olfactory receptor 8J3 (OR8J3) OTLQYWZG OR8J3_HUMAN Decreases Methylation [8]
Olfactory receptor 8J1 (OR8J1) OTWWGQW0 OR8J1_HUMAN Decreases Methylation [8]
Olfactory receptor 4S2 (OR4S2) OTHEO86H OR4S2_HUMAN Decreases Methylation [8]
LHFPL tetraspan subfamily member 5 protein (LHFPL5) OTNDTO5B LHPL5_HUMAN Decreases Methylation [8]
SWI/SNF complex subunit SMARCC2 (SMARCC2) OTC5SNMZ SMRC2_HUMAN Decreases Expression [29]
Iron-sulfur cluster transfer protein NUBPL (NUBPL) OTQMCSXT NUBPL_HUMAN Increases Methylation [8]
DEP domain-containing mTOR-interacting protein (DEPTOR) OTCBP1BT DPTOR_HUMAN Increases Methylation [8]
T-cell immunomodulatory protein (ITFG1) OTX0PCR3 TIP_HUMAN Decreases Methylation [8]
Glutamate receptor ionotropic, NMDA 3A (GRIN3A) OTQS9GYY NMD3A_HUMAN Increases Methylation [8]
Transmembrane channel-like protein 1 (TMC1) OTHYH8MU TMC1_HUMAN Increases Methylation [8]
Polycystin-1-like protein 1 (PKD1L1) OTLAARJ1 PK1L1_HUMAN Increases Methylation [8]
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 3 (ASAP3) OTQB4H1J ASAP3_HUMAN Increases Methylation [8]
Epidermal growth factor receptor kinase substrate 8-like protein 3 (EPS8L3) OT7XYA2T ES8L3_HUMAN Increases Methylation [8]
Epidermal growth factor receptor kinase substrate 8-like protein 1 (EPS8L1) OT83O8WI ES8L1_HUMAN Decreases Methylation [8]
Importin-4 (IPO4) OT2N5020 IPO4_HUMAN Increases Methylation [8]
Membrane progestin receptor beta (PAQR8) OTGZ8W9F PAQR8_HUMAN Decreases Methylation [8]
Dual specificity protein phosphatase 19 (DUSP19) OT0RRSG9 DUS19_HUMAN Decreases Methylation [8]
Splicing factor Cactin (CACTIN) OTO7UVK7 CATIN_HUMAN Increases Methylation [8]
AFG1-like ATPase (AFG1L) OTQ9VV5T AFG1L_HUMAN Increases Methylation [8]
Ankyrin repeat and SOCS box protein 10 (ASB10) OTYSZ9V6 ASB10_HUMAN Increases Methylation [8]
Autism susceptibility gene 2 protein (AUTS2) OTAEXHSC AUTS2_HUMAN Increases Methylation [8]
Cysteine/serine-rich nuclear protein 3 (CSRNP3) OTOANEHZ CSRN3_HUMAN Increases Methylation [8]
Phosphoinositide 3-kinase regulatory subunit 5 (PIK3R5) OT4LNXJU PI3R5_HUMAN Decreases Methylation [8]
Piezo-type mechanosensitive ion channel component 1 (PIEZO1) OTBG1FU4 PIEZ1_HUMAN Increases Methylation [8]
Phosphatidate phosphatase LPIN2 (LPIN2) OTRRTMXX LPIN2_HUMAN Increases Methylation [8]
Sorting nexin-19 (SNX19) OTGNS3HG SNX19_HUMAN Decreases Methylation [8]
Engulfment and cell motility protein 1 (ELMO1) OTY2ORXK ELMO1_HUMAN Decreases Methylation [8]
Delta-sarcoglycan (SGCD) OTRBL3NQ SGCD_HUMAN Increases Methylation [8]
A-kinase anchor protein 1, mitochondrial (AKAP1) OTIIB2JB AKAP1_HUMAN Increases Expression [10]
Estrogen receptor beta (ESR2) OTXNR2WQ ESR2_HUMAN Increases Expression [10]
Transcription initiation factor TFIID subunit 4B (TAF4B) OTCICY31 TAF4B_HUMAN Increases Methylation [8]
General transcription factor IIH subunit 4 (GTF2H4) OTPD1DIU TF2H4_HUMAN Decreases Methylation [8]
Histone acetyltransferase KAT6A (KAT6A) OT4TSQLG KAT6A_HUMAN Decreases Methylation [8]
Neuronal cell adhesion molecule (NRCAM) OT80HHQ2 NRCAM_HUMAN Increases Methylation [8]
Bcl-2-like protein 2 (BCL2L2) OTMKVO0J B2CL2_HUMAN Increases Expression [10]
Caspase-10 (CASP10) OTE6J88E CASPA_HUMAN Increases Methylation [8]
ATP-binding cassette sub-family C member 2 (ABCC2) OTJSIGV5 MRP2_HUMAN Increases Expression [34]
Fibroblast growth factor 13 (FGF13) OTHNNVSG FGF13_HUMAN Increases Methylation [8]
SWI/SNF complex subunit SMARCC1 (SMARCC1) OTUOMBE7 SMRC1_HUMAN Increases Expression [29]
Receptor-type tyrosine-protein phosphatase N2 (PTPRN2) OTL6SH28 PTPR2_HUMAN Increases Methylation [8]
Lipoma-preferred partner (LPP) OT6TU8SE LPP_HUMAN Increases Methylation [8]
Mediator of RNA polymerase II transcription subunit 12 (MED12) OTQZ4D2X MED12_HUMAN Increases Methylation [8]
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3 (ATP2A3) OTFYDEES AT2A3_HUMAN Increases Methylation [8]
Secretory carrier-associated membrane protein 4 (SCAMP4) OTSCZTJ5 SCAM4_HUMAN Increases Methylation [8]
Endoplasmic reticulum-Golgi intermediate compartment protein 1 (ERGIC1) OT351FKB ERGI1_HUMAN Decreases Methylation [8]
Terminal nucleotidyltransferase 5B (TENT5B) OTO2P28B TET5B_HUMAN Increases Methylation [8]
Collagen alpha-1(XXVI) chain (COL26A1) OTMS7RNF COQA1_HUMAN Decreases Methylation [8]
Isochorismatase domain-containing protein 2 (ISOC2) OT69N6MB ISOC2_HUMAN Increases Methylation [8]
Repulsive guidance molecule A (RGMA) OTZAMDO2 RGMA_HUMAN Increases Methylation [8]
Dedicator of cytokinesis protein 10 (DOCK10) OTI3MBLV DOC10_HUMAN Increases Methylation [8]
EF-hand domain-containing protein D2 (EFHD2) OTM9VMN3 EFHD2_HUMAN Increases Methylation [8]
Netrin-G2 (NTNG2) OTTY88DL NTNG2_HUMAN Increases Methylation [8]
Anaphase-promoting complex subunit 16 (ANAPC16) OTG9MUYS APC16_HUMAN Increases Methylation [8]
Rho guanine nucleotide exchange factor 26 (ARHGEF26) OTX0U8PX ARHGQ_HUMAN Increases Methylation [8]
PHD finger protein 21B (PHF21B) OTU5GLCQ PF21B_HUMAN Increases Methylation [8]
Polypeptide N-acetylgalactosaminyltransferase 14 (GALNT14) OT9BSDDQ GLT14_HUMAN Increases Methylation [8]
CKLF-like MARVEL transmembrane domain-containing protein 7 (CMTM7) OTI7Q2JW CKLF7_HUMAN Decreases Methylation [8]
Aurora kinase B (AURKB) OTIY4VHU AURKB_HUMAN Decreases Expression [9]
Protein FAM163A (FAM163A) OT0MYZ0F F163A_HUMAN Increases Methylation [8]
SH3 domain-containing YSC84-like protein 1 (SH3YL1) OTVXOONW SH3Y1_HUMAN Increases Methylation [8]
ATP-binding cassette sub-family C member 11 (ABCC11) OTVHL7OR MRP8_HUMAN Increases Methylation [8]
Cadherin-related family member 1 (CDHR1) OT1ORXCM CDHR1_HUMAN Decreases Methylation [8]
Membrane-spanning 4-domains subfamily A member 4A (MS4A4A) OTWV82RP M4A4A_HUMAN Decreases Methylation [8]
Protein maelstrom homolog (MAEL) OTZ2VU30 MAEL_HUMAN Decreases Methylation [8]
MAP/microtubule affinity-regulating kinase 4 (MARK4) OT6Z2TGV MARK4_HUMAN Increases Methylation [8]
Zeta-sarcoglycan (SGCZ) OTVGTEOD SGCZ_HUMAN Decreases Methylation [8]
Adenylate kinase 8 (AK8) OT2UF6YM KAD8_HUMAN Decreases Methylation [8]
bMERB domain-containing protein 1 (BMERB1) OT1IH086 MERB1_HUMAN Increases Methylation [8]
Junctional sarcoplasmic reticulum protein 1 (JSRP1) OT1AAYWO JSPR1_HUMAN Increases Methylation [8]
Cytosolic carboxypeptidase 4 (AGBL1) OT8NQLH0 CBPC4_HUMAN Decreases Methylation [8]
Nucleolar protein 4-like (NOL4L) OT14W6UW NOL4L_HUMAN Increases Methylation [8]
Retinol dehydrogenase 12 (RDH12) OTELFRRJ RDH12_HUMAN Increases Methylation [8]
N-terminal EF-hand calcium-binding protein 3 (NECAB3) OTRASC9G NECA3_HUMAN Increases Methylation [8]
Noelin-3 (OLFM3) OTBHPDTL NOE3_HUMAN Decreases Methylation [8]
Erythroid membrane-associated protein (ERMAP) OTKXBB52 ERMAP_HUMAN Decreases Methylation [8]
CUB and sushi domain-containing protein 1 (CSMD1) OTIVDSC4 CSMD1_HUMAN Decreases Methylation [8]
PHD finger protein 12 (PHF12) OTECRO7N PHF12_HUMAN Increases Methylation [8]
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1 (MAGI1) OTMV4ASV MAGI1_HUMAN Decreases Methylation [8]
Olfactory receptor 8B4 (OR8B4) OTT4T35X OR8B4_HUMAN Decreases Methylation [8]
Galactose-3-O-sulfotransferase 4 (GAL3ST4) OTCXGJGO G3ST4_HUMAN Increases Methylation [8]
Erbin (ERBIN) OTNWTUA8 ERBIN_HUMAN Increases Methylation [8]
Intraflagellar transport protein 140 homolog (IFT140) OT6KO5FH IF140_HUMAN Increases Methylation [8]
GPI transamidase component PIG-S (PIGS) OTCC4CEN PIGS_HUMAN Increases Methylation [8]
Tetraspanin-18 (TSPAN18) OTHSGPVB TSN18_HUMAN Decreases Methylation [8]
2-aminoethanethiol dioxygenase (ADO) OTRLGQ7V AEDO_HUMAN Increases Methylation [8]
Eyes absent homolog 1 (EYA1) OTHU807A EYA1_HUMAN Decreases Methylation [8]
G-protein coupled estrogen receptor 1 (GPER1) OTUK0TDC GPER1_HUMAN Increases Expression [43]
Prohibitin-2 (PHB2) OTCAX3AW PHB2_HUMAN Decreases Expression [10]
Ataxin-2 (ATXN2) OT465IGT ATX2_HUMAN Increases Methylation [8]
Tumor susceptibility gene 101 protein (TSG101) OT97UIXC TS101_HUMAN Increases Methylation [8]
Calcium and integrin-binding protein 1 (CIB1) OT4BVCRU CIB1_HUMAN Increases Methylation [8]
Histone H2B type 1-M (H2BC14) OTSDZZZY H2B1M_HUMAN Increases Methylation [8]
Cbp/p300-interacting transactivator 2 (CITED2) OT812TV7 CITE2_HUMAN Increases Expression [10]
Semaphorin-3C (SEMA3C) OTEGUY7F SEM3C_HUMAN Increases Methylation [8]
Testican-3 (SPOCK3) OTYSOOO7 TICN3_HUMAN Decreases Methylation [8]
SH3-containing GRB2-like protein 3-interacting protein 1 (SGIP1) OTQW6R3Z SGIP1_HUMAN Increases Methylation [8]
Uncharacterized protein C7orf50 (C7ORF50) OTDHN459 CG050_HUMAN Increases Methylation [8]
Ferroptosis suppressor protein 1 (AIFM2) OT57XWXO FSP1_HUMAN Increases Methylation [8]
Phagosome assembly factor 1 (PHAF1) OTF7ZOG6 PHAF1_HUMAN Increases Methylation [8]
NEDD4 family-interacting protein 1 (NDFIP1) OTIORSWF NFIP1_HUMAN Increases Methylation [8]
Death-inducer obliterator 1 (DIDO1) OT9PB547 DIDO1_HUMAN Increases Methylation [8]
CDK5 and ABL1 enzyme substrate 2 (CABLES2) OTGD9A2A CABL2_HUMAN Increases Methylation [8]
Tubulin-specific chaperone D (TBCD) OTS4JKNQ TBCD_HUMAN Increases Methylation [8]
E3 ubiquitin-protein ligase TRIM62 (TRIM62) OT15YO6N TRI62_HUMAN Decreases Methylation [8]
PHD finger protein 20 (PHF20) OTCBVH5P PHF20_HUMAN Increases Methylation [8]
Protein TALPID3 (KIAA0586) OTOZRC1U TALD3_HUMAN Increases Methylation [8]
Katanin p60 ATPase-containing subunit A-like 1 (KATNAL1) OTBUZ7KA KATL1_HUMAN Increases Methylation [8]
Chitinase domain-containing protein 1 (CHID1) OT4DIUKC CHID1_HUMAN Decreases Methylation [8]
Brother of CDO (BOC) OTXBCY9W BOC_HUMAN Decreases Methylation [8]
Sal-like protein 3 (SALL3) OTJ2LZKQ SALL3_HUMAN Affects Methylation [8]
Leucine-rich repeat-containing G-protein coupled receptor 4 (LGR4) OTIMWEK5 LGR4_HUMAN Increases Methylation [8]
Hydroxycarboxylic acid receptor 1 (HCAR1) OT5ZSESQ HCAR1_HUMAN Increases Methylation [8]
Caspase recruitment domain-containing protein 11 (CARD11) OTRCTLYC CAR11_HUMAN Increases Methylation [8]
Calcium-binding protein 8 (CALN1) OTN2XE4T CABP8_HUMAN Increases Methylation [8]
R-spondin-3 (RSPO3) OTZK8GDS RSPO3_HUMAN Increases Methylation [8]
Histone deacetylase 8 (HDAC8) OT5L4RYX HDAC8_HUMAN Increases Methylation [8]
Dual specificity protein phosphatase 16 (DUSP16) OTK7S078 DUS16_HUMAN Decreases Methylation [8]
Alpha-(1,6)-fucosyltransferase (FUT8) OTJJCVG1 FUT8_HUMAN Decreases Methylation [8]
Hyccin (HYCC1) OTO65AE3 HYCCI_HUMAN Increases Methylation [8]
Keratin-associated protein 2-1 (KRTAP2-1) OTV1SGF2 KRA21_HUMAN Increases Methylation [8]
F-box-like/WD repeat-containing protein TBL1XR1 (TBL1XR1) OTM3B3OA TBL1R_HUMAN Increases Methylation [8]
Reticulon-4 receptor (RTN4R) OT8J693X RTN4R_HUMAN Increases Methylation [8]
Forkhead box protein P3 (FOXP3) OTA9Z9OC FOXP3_HUMAN Increases Methylation [8]
E3 ubiquitin-protein ligase TRIM4 (TRIM4) OTLKQNKQ TRIM4_HUMAN Increases Methylation [8]
Tripartite motif-containing protein 2 (TRIM2) OT0V1YVC TRIM2_HUMAN Increases Methylation [8]
Cilia- and flagella-associated protein 74 (CFAP74) OTVW2BGR CFA74_HUMAN Increases Methylation [8]
SRC kinase signaling inhibitor 1 (SRCIN1) OTQZNQQ5 SRCN1_HUMAN Decreases Methylation [8]
Eukaryotic translation initiation factor 5A-2 (EIF5A2) OT4SY4KY IF5A2_HUMAN Decreases Methylation [8]
Hyaluronan and proteoglycan link protein 2 (HAPLN2) OT0G3KEQ HPLN2_HUMAN Decreases Methylation [8]
Phospholysine phosphohistidine inorganic pyrophosphate phosphatase (LHPP) OT9AGAIJ LHPP_HUMAN Increases Methylation [8]
Transmembrane protein 168 (TMEM168) OTJKZ6G9 TM168_HUMAN Increases Methylation [8]
B-cell lymphoma/leukemia 11A (BCL11A) OTI6ZBP6 BC11A_HUMAN Increases Methylation [8]
EH domain-containing protein 4 (EHD4) OT7G5JTT EHD4_HUMAN Increases Methylation [8]
Enhancer of polycomb homolog 1 (EPC1) OT3Q25ND EPC1_HUMAN Increases Methylation [8]
Sodium-coupled neutral amino acid symporter 1 (SLC38A1) OTO3VD5E S38A1_HUMAN Increases Methylation [8]
Chordin (CHRD) OTNM60Y1 CHRD_HUMAN Increases Methylation [8]
Cysteine-rich secretory protein LCCL domain-containing 1 (CRISPLD1) OT38HXJP CRLD1_HUMAN Increases Methylation [8]
Polyadenylate-binding protein 3 (PABPC3) OTTR9DPT PABP3_HUMAN Increases Methylation [8]
Tumor protein 63 (TP63) OT0WOOKQ P63_HUMAN Increases Methylation [8]
Thiamin pyrophosphokinase 1 (TPK1) OTCHPUD0 TPK1_HUMAN Increases Methylation [8]
Homeodomain-interacting protein kinase 3 (HIPK3) OT4WYQM2 HIPK3_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase PLK3 (PLK3) OT19CT2Z PLK3_HUMAN Increases Methylation [8]
Alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3-N-acetyl-galactosaminide alpha-2,6-sialyltransferase (ST6GALNAC4) OTJCJQI7 SIA7D_HUMAN Increases Methylation [8]
PR domain zinc finger protein 13 (PRDM13) OTUNAFQW PRD13_HUMAN Increases Methylation [8]
Dual specificity protein phosphatase 21 (DUSP21) OTZAGY5R DUS21_HUMAN Decreases Methylation [8]
Uncharacterized protein C19orf44 (C19ORF44) OTES5EZZ CS044_HUMAN Increases Methylation [8]
Histone-lysine N-methyltransferase SMYD3 (SMYD3) OT9YR20G SMYD3_HUMAN Affects Methylation [8]
Proton-activated chloride channel (PACC1) OTKBS8CC PACC1_HUMAN Increases Methylation [8]
Tetratricopeptide repeat protein 12 (TTC12) OTDB24YV TTC12_HUMAN Increases Methylation [8]
Probable ATP-dependent RNA helicase DDX31 (DDX31) OTNWY581 DDX31_HUMAN Increases Methylation [8]
Protein argonaute-3 (AGO3) OTNQGROH AGO3_HUMAN Affects Methylation [8]
Akirin-1 (AKIRIN1) OTINWTT9 AKIR1_HUMAN Increases Methylation [8]
Homeobox protein NANOG (NANOG) OTUEY1FM NANOG_HUMAN Increases Expression [44]
Adhesion G protein-coupled receptor L3 (ADGRL3) OT81Q8LY AGRL3_HUMAN Decreases Methylation [8]
Protein ERGIC-53-like (LMAN1L) OT2CSBR3 LMA1L_HUMAN Increases Methylation [8]
Histone-lysine N-methyltransferase PRDM16 (PRDM16) OT0BGA27 PRD16_HUMAN Decreases Methylation [8]
Solute carrier family 38 member 10 (SLC38A10) OTXPUL6S S38AA_HUMAN Increases Methylation [8]
Mucin-5B (MUC5B) OTPW6K5C MUC5B_HUMAN Increases Methylation [8]
Transcription factor HES-4 (HES4) OTCGMQDT HES4_HUMAN Increases Methylation [8]
Helicase MOV-10 (MOV10) OT0KAY9G MOV10_HUMAN Increases Methylation [8]
Synaptotagmin-like protein 2 (SYTL2) OTUIOWKL SYTL2_HUMAN Increases Methylation [8]
E3 ubiquitin-protein ligase MSL2 (MSL2) OTVPQYBG MSL2_HUMAN Increases Methylation [8]
Mineralization regulator ANKH (ANKH) OTCN25R5 ANKH_HUMAN Decreases Methylation [8]
Roundabout homolog 2 (ROBO2) OTFJ9FQW ROBO2_HUMAN Decreases Methylation [8]
Fibrosin-1-like protein (FBRSL1) OT4BPXGG FBSL_HUMAN Increases Methylation [8]
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (PDE11A) OT9X261C PDE11_HUMAN Increases Methylation [8]
LYR motif-containing protein 4 (LYRM4) OTK6JCKL LYRM4_HUMAN Increases Methylation [8]
Regulation of nuclear pre-mRNA domain-containing protein 1B (RPRD1B) OTB41D5K RPR1B_HUMAN Increases Methylation [8]
Gephyrin (GPHN) OTAKK1SV GEPH_HUMAN Increases Methylation [8]
Transcriptional and immune response regulator (TCIM) OTARUXQF TCIM_HUMAN Increases Expression [10]
Matrix-remodeling-associated protein 5 (MXRA5) OTXZBWCU MXRA5_HUMAN Decreases Methylation [8]
CTP synthase 2 (CTPS2) OT2X9YO1 PYRG2_HUMAN Increases Methylation [8]
Bromodomain adjacent to zinc finger domain protein 1A (BAZ1A) OTWHOVZS BAZ1A_HUMAN Increases Methylation [8]
Solute carrier family 2, facilitated glucose transporter member 9 (SLC2A9) OTENU71Z GTR9_HUMAN Increases Methylation [8]
Interleukin-17 receptor B (IL17RB) OT0KDNSF I17RB_HUMAN Decreases Expression [9]
Double-stranded RNA-specific editase B2 (ADARB2) OTDJKS39 RED2_HUMAN Increases Methylation [8]
Protein DEPP1 (DEPP1) OTB36PHJ DEPP1_HUMAN Decreases Expression [26]
E3 ubiquitin-protein ligase RNF146 (RNF146) OTE4CO7E RN146_HUMAN Decreases Methylation [8]
Double-stranded RNA-binding protein Staufen homolog 2 (STAU2) OTORNUIF STAU2_HUMAN Decreases Methylation [8]
tRNA:m(4)X modification enzyme TRM13 homolog (TRMT13) OT2H0MCE TRM13_HUMAN Increases Methylation [8]
F-box only protein 28 (FBXO28) OTKTMVC4 FBX28_HUMAN Decreases Methylation [8]
Transmembrane protein 51 (TMEM51) OTZCW8XJ TMM51_HUMAN Increases Methylation [8]
Solute carrier family 52, riboflavin transporter, member 1 (SLC52A1) OTQ4D276 S52A1_HUMAN Increases Methylation [8]
CUE domain-containing protein 1 (CUEDC1) OTQ7V4FF CUED1_HUMAN Increases Methylation [8]
Membrane progestin receptor gamma (PAQR5) OTGGWXQE PAQR5_HUMAN Increases Methylation [8]
Rho guanine nucleotide exchange factor 38 (ARHGEF38) OTA6K93F ARH38_HUMAN Increases Methylation [8]
Odorant-binding protein 2a (OBP2A) OTBIJ5TI OBP2A_HUMAN Increases Methylation [8]
Solute carrier family 2, facilitated glucose transporter member 8 (SLC2A8) OTPT2I7B SL2A8_HUMAN Increases Methylation [8]
Sodium channel regulatory subunit beta-3 (SCN3B) OTNTQT9O SCN3B_HUMAN Decreases Methylation [8]
Probable ATP-dependent RNA helicase DDX56 (DDX56) OTGURA53 DDX56_HUMAN Increases Methylation [8]
Cytochrome c oxidase assembly factor 4 homolog, mitochondrial (COA4) OT8319UQ COA4_HUMAN Increases Methylation [8]
24-hydroxycholesterol 7-alpha-hydroxylase (CYP39A1) OTBAJT4I CP39A_HUMAN Increases Methylation [8]
Cadherin EGF LAG seven-pass G-type receptor 1 (CELSR1) OT7PS8O1 CELR1_HUMAN Increases Methylation [8]
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A-like protein 1 (SMARCAL1) OTTKXLUZ SMAL1_HUMAN Decreases Methylation [8]
Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2BP1) OT9G360P IF2B1_HUMAN Increases Methylation [8]
Ral guanine nucleotide dissociation stimulator-like 1 (RGL1) OTY6ZHVA RGL1_HUMAN Increases Methylation [8]
Interleukin-1 receptor accessory protein-like 1 (IL1RAPL1) OTW3T4B2 IRPL1_HUMAN Decreases Methylation [8]
CXXC-type zinc finger protein 1 (CXXC1) OTO10D1N CXXC1_HUMAN Decreases Methylation [8]
Neurotrimin (NTM) OTHF0UQU NTRI_HUMAN Decreases Methylation [8]
Costars family protein ABRACL (ABRACL) OT95T48Q ABRAL_HUMAN Increases Methylation [8]
Coiled-coil domain-containing protein 180 (CCDC180) OT4AL3LW CC180_HUMAN Increases Methylation [8]
Neuronal tyrosine-phosphorylated phosphoinositide-3-kinase adapter 2 (NYAP2) OT80PO4Q NYAP2_HUMAN Increases Methylation [8]
Rho GTPase-activating protein 20 (ARHGAP20) OTG1STV8 RHG20_HUMAN Increases Methylation [8]
KAT8 regulatory NSL complex subunit 3 (KANSL3) OTWXDTLY KANL3_HUMAN Decreases Methylation [8]
Arginine-glutamic acid dipeptide repeats protein (RERE) OT3G4GBZ RERE_HUMAN Increases Methylation [8]
Sperm microtubule associated protein 2 (SPMAP2) OTLJPJ39 SPMA2_HUMAN Increases Methylation [8]
Protein IMPACT (IMPACT) OTQ923OB IMPCT_HUMAN Increases Methylation [8]
Copine-7 (CPNE7) OTR0FJ8A CPNE7_HUMAN Increases Methylation [8]
Dickkopf-related protein 3 (DKK3) OTDU94EY DKK3_HUMAN Increases Methylation [8]
PTB domain-containing engulfment adapter protein 1 (GULP1) OT1WMVDH GULP1_HUMAN Increases Methylation [8]
Gamma-aminobutyric acid type B receptor subunit 1 (GABBR1) OTU5A52J GABR1_HUMAN Increases Methylation [8]
Alpha-catulin (CTNNAL1) OTESJ6JD CTNL1_HUMAN Increases Methylation [8]
Protein CLN8 (CLN8) OT0D4CB5 CLN8_HUMAN Decreases Methylation [8]
Tripartite motif-containing protein 10 (TRIM10) OTEO4UCZ TRI10_HUMAN Increases Methylation [8]
Death domain-associated protein 6 (DAXX) OTX6O7PL DAXX_HUMAN Increases Methylation [8]
tRNA (FTSJ1) OTNE7W96 TRM7_HUMAN Increases Methylation [8]
Dynein axonemal heavy chain 17 (DNAH17) OT4G6E70 DYH17_HUMAN Increases Methylation [8]
Regulator of G-protein signaling 17 (RGS17) OT5RVUDS RGS17_HUMAN Decreases Methylation [8]
Olfactory receptor 12D3 (OR12D3) OTQ9XNBB O12D3_HUMAN Increases Methylation [8]
Deleted in malignant brain tumors 1 protein (DMBT1) OTVNU9D9 DMBT1_HUMAN Increases Expression [45]
Switch-associated protein 70 (SWAP70) OTPHT2QD SWP70_HUMAN Decreases Methylation [8]
Contactin-associated protein-like 2 (CNTNAP2) OT48T2ZP CNTP2_HUMAN Increases Methylation [8]
Interleukin-17B (IL17B) OTS86H50 IL17B_HUMAN Decreases Methylation [8]
Sodium channel protein type 11 subunit alpha (SCN11A) OTY0HJJZ SCNBA_HUMAN Increases Methylation [8]
Cardiolipin synthase (CRLS1) OT7XNL0K CRLS1_HUMAN Decreases Methylation [8]
Ectonucleotide pyrophosphatase/phosphodiesterase family member 5 (ENPP5) OTY807N5 ENPP5_HUMAN Decreases Methylation [8]
Anaphase-promoting complex subunit 2 (ANAPC2) OTAGLIAO ANC2_HUMAN Increases Methylation [8]
ADP-ribosylation factor-binding protein GGA1 (GGA1) OTSEV0JU GGA1_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase tousled-like 1 (TLK1) OTICTXI8 TLK1_HUMAN Increases Methylation [8]
POU domain, class 2, transcription factor 3 (POU2F3) OTIOOJWD PO2F3_HUMAN Increases Methylation [8]
Mucin-12 (MUC12) OTYDC13T MUC12_HUMAN Increases Methylation [8]
F-box only protein 5 (FBXO5) OTTR957W FBX5_HUMAN Decreases Expression [9]
Histone deacetylase 9 (HDAC9) OTO8O0LF HDAC9_HUMAN Decreases Methylation [8]
Protein argonaute-2 (AGO2) OT4JY32Q AGO2_HUMAN Increases Methylation [8]
Bromodomain and PHD finger-containing protein 3 (BRPF3) OTRNO4PR BRPF3_HUMAN Increases Methylation [8]
DENN domain-containing protein 2A (DENND2A) OT01E1PL DEN2A_HUMAN Increases Methylation [8]
Cell cycle progression protein 1 (CCPG1) OT0IHDKL CCPG1_HUMAN Increases Methylation [8]
Myocardin-related transcription factor B (MRTFB) OT9OXGS9 MRTFB_HUMAN Decreases Methylation [8]
Protein HEG homolog 1 (HEG1) OT3CUXA7 HEG1_HUMAN Increases Methylation [8]
Glutamate receptor ionotropic, delta-1 (GRID1) OTJ3WIKC GRID1_HUMAN Increases Methylation [8]
Transcription factor MafF (MAFF) OT9B7MX0 MAFF_HUMAN Increases Expression [10]
Protein ATP1B4 (ATP1B4) OT2YC9GZ AT1B4_HUMAN Decreases Methylation [8]
Dual specificity protein phosphatase CDC14A (CDC14A) OTL10OY6 CC14A_HUMAN Increases Methylation [8]
FAS-associated factor 1 (FAF1) OTGAMLM4 FAF1_HUMAN Increases Methylation [8]
Protein timeless homolog (TIMELESS) OTD8DCBJ TIM_HUMAN Decreases Expression [9]
Microtubule-actin cross-linking factor 1, isoforms 1/2/3/4/5 (MACF1) OTVIHD77 MACF1_HUMAN Increases Methylation [8]
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 1 (AGAP1) OTVX8835 AGAP1_HUMAN Affects Methylation [8]
Trinucleotide repeat-containing gene 6B protein (TNRC6B) OTGVT0SH TNR6B_HUMAN Increases Methylation [8]
Transcription factor 19 (TCF19) OT7NKLF9 TCF19_HUMAN Decreases Expression [9]
Type 2 lactosamine alpha-2,3-sialyltransferase (ST3GAL6) OTB17Q43 SIA10_HUMAN Increases Methylation [8]
UDP-N-acetylglucosamine transporter (SLC35A3) OTG92DK5 S35A3_HUMAN Increases Methylation [8]
Protein strawberry notch homolog 2 (SBNO2) OT1C6J3K SBNO2_HUMAN Increases Methylation [8]
Angiomotin-like protein 2 (AMOTL2) OTRCTKV9 AMOL2_HUMAN Increases Methylation [8]
Serine/threonine-protein kinase SIK3 (SIK3) OTH0V1L5 SIK3_HUMAN Increases Methylation [8]
Peptidyl-prolyl cis-trans isomerase-like 1 (PPIL1) OTS5S837 PPIL1_HUMAN Increases Methylation [8]
Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1) OT8M52QY LMBL1_HUMAN Decreases Methylation [8]
Transformation/transcription domain-associated protein (TRRAP) OT68OI2Y TRRAP_HUMAN Increases Methylation [8]
FERM, ARHGEF and pleckstrin domain-containing protein 1 (FARP1) OTL1EBTM FARP1_HUMAN Increases Methylation [8]
Centrosomal protein of 170 kDa protein B (CEP170B) OTYB0VGH C170B_HUMAN Increases Methylation [8]
Protein PRRC2C (PRRC2C) OTBX3MXM PRC2C_HUMAN Increases Methylation [8]
Ankyrin repeat and SOCS box protein 4 (ASB4) OTI4AFZL ASB4_HUMAN Increases Methylation [8]
Ankyrin repeat and SOCS box protein 3 (ASB3) OTI3TK38 ASB3_HUMAN Decreases Methylation [8]
AP-4 complex subunit sigma-1 (AP4S1) OTM3QBU8 AP4S1_HUMAN Decreases Methylation [8]
Protocadherin gamma-A1 (PCDHGA1) OTR1U1LI PCDG1_HUMAN Increases Methylation [8]
Methyltransferase N6AMT1 (N6AMT1) OTOK0NYQ N6MT1_HUMAN Increases Methylation [8]
Sorting nexin-8 (SNX8) OTMG63Z6 SNX8_HUMAN Increases Methylation [8]
Nuclear receptor corepressor 2 (NCOR2) OTY917X0 NCOR2_HUMAN Increases Methylation [8]
Junctional adhesion molecule A (F11R) OTGHPAV6 JAM1_HUMAN Decreases Methylation [8]
Brefeldin A-inhibited guanine nucleotide-exchange protein 1 (ARFGEF1) OTPAU0L4 BIG1_HUMAN Increases Methylation [8]
Synphilin-1 (SNCAIP) OTH8VNOK SNCAP_HUMAN Increases Methylation [8]
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6L (TAF6L) OTQLO30U TAF6L_HUMAN Increases Methylation [8]
Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2) OT4ZSEEE IF2B2_HUMAN Increases Methylation [8]
Nuclear receptor coactivator 3 (NCOA3) OTBX300Z NCOA3_HUMAN Increases Expression [10]
Calmodulin-binding transcription activator 1 (CAMTA1) OTAN1S5B CMTA1_HUMAN Increases Methylation [8]
Ras-related and estrogen-regulated growth inhibitor (RERG) OTF6MMLV RERG_HUMAN Affects Response To Substance [29]
Serine/threonine-protein kinase mTOR (MTOR) OTHH8KU7 MTOR_HUMAN Decreases Response To Substance [9]
Breast cancer anti-estrogen resistance protein 3 (BCAR3) OTPJ17M8 BCAR3_HUMAN Affects Response To Substance [29]
FK506-binding protein-like (FKBPL) OTR9ND6K FKBPL_HUMAN Increases Response To Substance [46]
Anterior gradient protein 2 homolog (AGR2) OTRRZT7W AGR2_HUMAN Affects Response To Substance [47]
AT-rich interactive domain-containing protein 1A (ARID1A) OTRWDV3P ARI1A_HUMAN Decreases Response To Substance [48]
Broad substrate specificity ATP-binding cassette transporter ABCG2 (ABCG2) OTW8V2V1 ABCG2_HUMAN Affects Response To Substance [29]
Artemin (ARTN) OTWIWGL6 ARTN_HUMAN Decreases Response To Substance [49]
Cyclin-dependent kinase 12 (CDK12) OTZUDGNU CDK12_HUMAN Affects Response To Substance [50]
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⏷ Show the Full List of 985 DOT(s)
Indication(s) of PF-05212384
Disease Entry ICD 11 Status REF
Solid tumour/cancer 2A00-2F9Z Phase 2 [3]
PF-05212384 Interacts with 2 DTT Molecule(s)
DTT Name DTT ID UniProt ID Mode of Action REF
Serine/threonine-protein kinase mTOR (mTOR) TTCJG29 MTOR_HUMAN Modulator [51]
PI3-kinase gamma (PIK3CG) TTHBTOP PK3CG_HUMAN Modulator [51]
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Test Results of This Drug Combination in Other Disease Systems

Indication DrugCom ID Cell Line Status REF
Breast Cancer DCDKVGD N. A. Phase 3 [1]
------------------------------------------------------------------------------------

References

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3 URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7940).
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